3-amino-2-hydroxy-4-phenylbutanoic acid has been researched along with darunavir in 1 studies
| Studies (3-amino-2-hydroxy-4-phenylbutanoic acid) | Trials (3-amino-2-hydroxy-4-phenylbutanoic acid) | Recent Studies (post-2010) (3-amino-2-hydroxy-4-phenylbutanoic acid) | Studies (darunavir) | Trials (darunavir) | Recent Studies (post-2010) (darunavir) |
|---|---|---|---|---|---|
| 42 | 0 | 3 | 1,148 | 224 | 780 |
| Protein | Taxonomy | 3-amino-2-hydroxy-4-phenylbutanoic acid (IC50) | darunavir (IC50) |
|---|---|---|---|
| Chain A, HIV-1 protease | Human immunodeficiency virus 1 | 0.0028 | |
| Chain B, HIV-1 protease | Human immunodeficiency virus 1 | 0.0028 | |
| Chain A, HIV-1 protease | Human immunodeficiency virus 1 | 0.0028 | |
| Chain B, HIV-1 protease | Human immunodeficiency virus 1 | 0.0028 | |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | 6.6 | |
| Protease | Human immunodeficiency virus 1 | 0.063 | |
| Protease | Human immunodeficiency virus 1 | 0.0014 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Adachi, M; Hayashi, Y; Hidaka, K; Kameoka, M; Kempf, DJ; Kimura, T; Kiso, Y; Kuroki, R; McDaniel, KF; Nguyen, JT; Sankaranarayanan, R; Wang, J | 1 |
1 other study(ies) available for 3-amino-2-hydroxy-4-phenylbutanoic acid and darunavir
| Article | Year |
|---|---|
Identification of Highly Potent Human Immunodeficiency Virus Type-1 Protease Inhibitors against Lopinavir and Darunavir Resistant Viruses from Allophenylnorstatine-Based Peptidomimetics with P2 Tetrahydrofuranylglycine.
Topics: Crystallography, X-Ray; Darunavir; Drug Resistance, Viral; Glycine; HIV Protease; HIV Protease Inhibitors; HIV-1; Humans; Lopinavir; Peptidomimetics; Phenylbutyrates; Serum; Structure-Activity Relationship | 2018 |