Compounds > 3-amino-1-4-dimethyl-5h-pyrido(4-3-b)indole

3-amino-1-4-dimethyl-5h-pyrido(4-3-b)indole and cobaltous-chloride

3-amino-1-4-dimethyl-5h-pyrido(4-3-b)indole has been researched along with cobaltous-chloride* in 2 studies

Other Studies

2 other study(ies) available for 3-amino-1-4-dimethyl-5h-pyrido(4-3-b)indole and cobaltous-chloride

Article	Year
Mutagenicity of various chemicals including nickel and cobalt compounds in cultured mouse FM3A cells. Mutation research, 1991, Volume: 261, Issue:2 Employing a suspension culture of FM3A cells, we examined the cytotoxic and mutagenic effects of various chemical compounds. Mutagenicity of various types of mutagens (MNNG, ENNG, sterigmatocystin, mitomycin C, Trp-P-1, and X-rays) was sensitively detected by this assay. Mutagenicity of Trp-P-2 was detected in the presence of an activating enzyme system. Nickel(II) and cobalt(II) compounds (NiCl2, Ni(CH3COO)2, nickel complex [(C2H5)4N]2 [NiCl4], CoCl2, and a cobalt complex [(C2H5)4N]2-[CoCl4]) were cytotoxic to FM3A cells at concentrations of over 1 X 10(-4) M, and produced 2-6-fold increases of the control in the average number of 6-thioguanine-resistant (6TGr) colonies over a very narrow concentration range of 2-4 X 10(-4) M. Comparison of the mutagenicity of various chemical compounds suggested that some of the nickel(II) and cobalt(II) compounds were very weak mutagens. Topics: Acetates; Acetic Acid; Animals; Carbolines; Cell Line; Cell Survival; Cobalt; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; In Vitro Techniques; Mice; Mice, Inbred C3H; Mitomycin; Mutagenicity Tests; Mutagens; Nickel; Sterigmatocystin; X-Rays	1991
Antimutagenic action of cobaltous chloride on Trp-P-1-induced mutations in Salmonella typhimurium TA98 and TA1538. Mutation research, 1982, Volume: 95, Issue:2-3 Topics: Carbolines; Cobalt; Genetic Code; Mutagenicity Tests; Mutagens; Mutation; Salmonella typhimurium; Transcription, Genetic	1982

Article

Year

Mutagenicity of various chemicals including nickel and cobalt compounds in cultured mouse FM3A cells.

Mutation research, 1991, Volume: 261, Issue:2

Employing a suspension culture of FM3A cells, we examined the cytotoxic and mutagenic effects of various chemical compounds. Mutagenicity of various types of mutagens (MNNG, ENNG, sterigmatocystin, mitomycin C, Trp-P-1, and X-rays) was sensitively detected by this assay. Mutagenicity of Trp-P-2 was detected in the presence of an activating enzyme system. Nickel(II) and cobalt(II) compounds (NiCl2, Ni(CH3COO)2, nickel complex [(C2H5)4N]2 [NiCl4], CoCl2, and a cobalt complex [(C2H5)4N]2-[CoCl4]) were cytotoxic to FM3A cells at concentrations of over 1 X 10(-4) M, and produced 2-6-fold increases of the control in the average number of 6-thioguanine-resistant (6TGr) colonies over a very narrow concentration range of 2-4 X 10(-4) M. Comparison of the mutagenicity of various chemical compounds suggested that some of the nickel(II) and cobalt(II) compounds were very weak mutagens.

Topics: Acetates; Acetic Acid; Animals; Carbolines; Cell Line; Cell Survival; Cobalt; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; In Vitro Techniques; Mice; Mice, Inbred C3H; Mitomycin; Mutagenicity Tests; Mutagens; Nickel; Sterigmatocystin; X-Rays

1991

Antimutagenic action of cobaltous chloride on Trp-P-1-induced mutations in Salmonella typhimurium TA98 and TA1538.

Mutation research, 1982, Volume: 95, Issue:2-3

Topics: Carbolines; Cobalt; Genetic Code; Mutagenicity Tests; Mutagens; Mutation; Salmonella typhimurium; Transcription, Genetic

1982