3-amino-1-4-dimethyl-5h-pyrido(4-3-b)indole has been researched along with baicalein* in 1 studies
1 other study(ies) available for 3-amino-1-4-dimethyl-5h-pyrido(4-3-b)indole and baicalein
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Antimutagenic activity against trp-P-1 of the edible Thai plant, Oroxylum indicum vent.
A methanolic extract of Oroxylum indicum strongly inhibited the mutagenicity of Trp-P-1 in an Ames test. The major antimutagenic constituent was identified as baicalein with an IC50 value of 2.78+/-0.15 microM. The potent antimutagenicity of the extract was correlated with the high content (3.95+/-0.43%, dry weight) of baicalein. Baicalein acted as a desmutagen since it inhibited the N-hydroxylation of Trp-P-2. Topics: Antimutagenic Agents; Carbolines; Chromatography, High Pressure Liquid; Flavanones; Flavonoids; Fruit; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Mutagenicity Tests; Mutagens; Plant Extracts; Plants, Edible; Spectrophotometry, Ultraviolet; Thailand | 2001 |