3,7-dimethyl-1-propargylxanthine and caffeine

3,7-dimethyl-1-propargylxanthine has been researched along with caffeine in 24 studies

Research

Studies (24)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (8.33)	18.7374
1990's	12 (50.00)	18.2507
2000's	8 (33.33)	29.6817
2010's	2 (8.33)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Jacobson, KA; van Galen, PJ; Williams, M	1
Daly, JW; Padgett, WL; Shamim, MT	1
Frobenius, W; Geis, U; Hipp, J; Müller, CE; Pawłowski, M; Sandoval-Ramírez, J; Schobert, U; Suzuki, F	1
Jacobson, KA; Kim, HS; Kim, SA; Linden, J; Marshall, MA; Melman, N; Müller, CE	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Akkari, R; Borrmann, T; Brunschweiger, A; Drabczyńska, A; Hockemeyer, J; Kieć-Kononowicz, K; Koch, P; Köse, M; Küppers, P; Müller, CE; Radjainia, H; Schlenk, M	1
Abla, KA; Carney, JM; Daly, JW; Seale, TW; Shamim, MT	1
Fochtmann, L; Francis, A	1
Fink, JS; Pollack, AE	1
Shaban, M; Smith, RA; Stone, TW	1
Kaneko, S; Mizuno, K; Okada, M	1
Hespel, P; Richter, EA; Vergauwen, L	1
Kaneko, S; Okada, M	1
Kaneko, S; Kawata, Y; Kondo, T; Mizuno, K; Murakami, T; Okada, M; Wada, K	1
Daly, JW; Shi, D	1
Baldo, BA; Koob, GF; Markou, A	1
Poon, A; Sawynok, J	1
Capasso, A	1
Beilstein, M; Castagnoli, K; Castagnoli, N; Chen, JF; Petzer, JP; Schwarzschild, MA; Sonsalla, PK; Staal, R; Xu, K; Xu, YH	1
Hamann, M; Richter, A	1
Cheng, H; Ouyang, K; Qin, X; Wang, X; Wu, C; Yang, D; Zhang, C; Zheng, H; Zhou, Z	1
Coskun, C; Mutlu, D; Savci, V; Suzer, O; Yalcin, M; Yilmaz, MS	1
Capasso, A; Gallo, C	1
Chatterjee, D; Chiu, GS; Darmody, PT; Freund, GG; Johnson, RW; Meling, DD; Walsh, JP	1

Reviews

1 review(s) available for 3,7-dimethyl-1-propargylxanthine and caffeine

Article	Year
Adenosine receptors: pharmacology, structure-activity relationships, and therapeutic potential. Journal of medicinal chemistry, 1992, Feb-07, Volume: 35, Issue:3 Topics: Adenosine; Animals; Humans; Models, Chemical; Receptors, Purinergic; Second Messenger Systems; Structure-Activity Relationship	1992

Other Studies

23 other study(ies) available for 3,7-dimethyl-1-propargylxanthine and caffeine

Article	Year
Analogues of caffeine and theophylline: effect of structural alterations on affinity at adenosine receptors. Journal of medicinal chemistry, 1986, Volume: 29, Issue:7 Topics: Animals; Caffeine; Cell Membrane; Cerebral Cortex; Indicators and Reagents; Mass Spectrometry; Rats; Receptors, Purinergic; Structure-Activity Relationship; Theophylline; Xanthines	1986
Synthesis and structure-activity relationships of 3,7-dimethyl-1-propargylxanthine derivatives, A2A-selective adenosine receptor antagonists. Journal of medicinal chemistry, 1997, Dec-19, Volume: 40, Issue:26 Topics: Adenosine; Animals; Binding, Competitive; Brain; Caffeine; Molecular Structure; Phenethylamines; Protein Binding; Purinergic P1 Receptor Antagonists; Rats; Receptors, Purinergic P1; Structure-Activity Relationship; Theobromine; Xanthines	1997
Structure-activity relationships at human and rat A2B adenosine receptors of xanthine derivatives substituted at the 1-, 3-, 7-, and 8-positions. Journal of medicinal chemistry, 2002, May-23, Volume: 45, Issue:11 Topics: Animals; Binding, Competitive; Cell Line; Cloning, Molecular; Humans; Ligands; Purinergic P1 Receptor Antagonists; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2B; Receptors, Purinergic P1; Recombinant Proteins; Structure-Activity Relationship; Xanthines	2002
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
1,3-Dialkyl-substituted tetrahydropyrimido[1,2-f]purine-2,4-diones as multiple target drugs for the potential treatment of neurodegenerative diseases. Bioorganic & medicinal chemistry, 2013, Dec-01, Volume: 21, Issue:23 Topics: Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Caffeine; CHO Cells; Cricetulus; Humans; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neurodegenerative Diseases; Purinergic P1 Receptor Antagonists; Purines; Xanthines	2013
3,7-Dimethyl-1-propargylxanthine: a potent and selective in vivo antagonist of adenosine analogs. Life sciences, 1988, Volume: 43, Issue:21 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Body Temperature; Caffeine; Male; Mice; Mice, Inbred DBA; Motor Activity; Reference Values; Theobromine; Theophylline	1988
Reduced proconvulsant activity of caffeine in rats after a series of electroconvulsive seizures. Psychopharmacology, 1995, Volume: 119, Issue:1 Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Caffeine; Dose-Response Relationship, Drug; Electroconvulsive Therapy; Electroshock; Male; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Seizures; Theobromine; Time Factors	1995
Adenosine antagonists potentiate D2 dopamine-dependent activation of Fos in the striatopallidal pathway. Neuroscience, 1995, Volume: 68, Issue:3 Topics: Adenosine; Adrenergic Uptake Inhibitors; Animals; Caffeine; Dopamine Agonists; Ergolines; Genes, fos; Globus Pallidus; Immunohistochemistry; Male; Neostriatum; Neural Pathways; Phosphodiesterase Inhibitors; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Reserpine; Theobromine; Theophylline	1995
Purine suppression of proliferation of Sertoli-like TM4 cells in culture. Cell proliferation, 1995, Volume: 28, Issue:12 Topics: Adenosine; Animals; Caffeine; Cell Division; Cells, Cultured; Male; Mice; Purinergic P1 Receptor Antagonists; Purines; Receptors, Purinergic P1; Sertoli Cells; Theobromine; Theophylline	1995
Adenosine A1 and A2 receptors modulate extracellular dopamine levels in rat striatum. Neuroscience letters, 1996, Jul-05, Volume: 212, Issue:1 Topics: Adenosine; Animals; Antihypertensive Agents; Caffeine; Camptothecin; Dopamine; Enzyme Inhibitors; Extracellular Space; Irinotecan; Male; Microdialysis; Neostriatum; Phenethylamines; Phosphodiesterase Inhibitors; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Theobromine; Vasodilator Agents	1996
Adenosine exerts a glycogen-sparing action in contracting rat skeletal muscle. The American journal of physiology, 1997, Volume: 272, Issue:5 Pt 1 Topics: Adenosine; Animals; Caffeine; Cyclic AMP; Drug Combinations; Glycogen; Glycogen Synthase; Male; Muscle Contraction; Muscle, Skeletal; Phosphorylase a; Rats; Rats, Wistar; Theobromine; Xanthines	1997
Pharmacological interactions between magnesium ion and adenosine on monoaminergic system in the central nervous system. Magnesium research, 1998, Volume: 11, Issue:4 Topics: Adenosine; Animals; Biogenic Monoamines; Caffeine; Carbamazepine; Central Nervous System; Central Nervous System Stimulants; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Hippocampus; Magnesium; Male; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Serotonin; Theobromine; Theophylline; Visual Cortex	1998
Differential effects of adenosine receptor subtypes on release and reuptake of hippocampal serotonin. The European journal of neuroscience, 1999, Volume: 11, Issue:1 Topics: Adenosine; Animals; Antihypertensive Agents; Biological Transport; Caffeine; Central Nervous System Stimulants; Fluoxetine; Hippocampus; Male; Microdialysis; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quipazine; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptor, Adenosine A3; Receptors, Purinergic P1; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Theobromine; Theophylline; Vasodilator Agents	1999
Chronic effects of xanthines on levels of central receptors in mice. Cellular and molecular neurobiology, 1999, Volume: 19, Issue:6 Topics: 1-Methyl-3-isobutylxanthine; Animals; Brain Chemistry; Caffeine; Calcium Channels; Central Nervous System Stimulants; Cerebral Cortex; Corpus Striatum; Drug Interactions; Gene Expression Regulation; Male; Mice; Nerve Tissue Proteins; Pentoxifylline; Radioligand Assay; Receptors, Cholinergic; Receptors, Drug; Receptors, GABA; Receptors, Purinergic P1; Receptors, Serotonin; Theobromine; Theophylline; Xanthines	1999
Role of adenosine A2 receptors in brain stimulation reward under baseline conditions and during cocaine withdrawal in rats. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1999, Dec-15, Volume: 19, Issue:24 Topics: Adenosine; Animals; Brain; Caffeine; Cocaine; Differential Threshold; Dopamine Uptake Inhibitors; Drug Interactions; Electric Stimulation; Male; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Reaction Time; Receptors, Purinergic P1; Reference Values; Reward; Substance Withdrawal Syndrome; Theobromine	1999
Antinociceptive and anti-inflammatory properties of an adenosine kinase inhibitor and an adenosine deaminase inhibitor. European journal of pharmacology, 1999, Nov-19, Volume: 384, Issue:2-3 Topics: Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adenosine Kinase; Analgesics; Animals; Anti-Inflammatory Agents; Caffeine; Carrageenan; Central Nervous System Stimulants; Deoxyadenosines; Dose-Response Relationship, Drug; Drug Synergism; Edema; Enzyme Inhibitors; Hindlimb; Hyperalgesia; Injections, Spinal; Male; Nociceptors; Pain; Pentostatin; Proto-Oncogene Proteins c-fos; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Spinal Cord; Theobromine; Time Factors	1999
Adenosine receptors are involved in the control of acute naloxone-precipitated withdrawal: in vitro evidence. Life sciences, 2000, Volume: 66, Issue:10 Topics: Adenosine; Animals; Caffeine; Dipyridamole; Guinea Pigs; Ileum; In Vitro Techniques; Male; Naloxone; Narcotic Antagonists; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Substance Withdrawal Syndrome; Theobromine; Theophylline	2000
Neuroprotection by caffeine and A(2A) adenosine receptor inactivation in a model of Parkinson's disease. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, May-15, Volume: 21, Issue:10 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Caffeine; Catechols; Corpus Striatum; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Immunity, Innate; Injections, Intraperitoneal; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neuroprotective Agents; Parkinsonian Disorders; Purinergic P1 Receptor Antagonists; Purines; Pyrimidines; Receptor, Adenosine A2A; Receptors, Purinergic P1; Theobromine; Triazoles; Xanthines	2001
Effects of adenosine receptor agonists and antagonists in a genetic animal model of primary paroxysmal dystonia. British journal of pharmacology, 2001, Volume: 134, Issue:2 Topics: Adenosine; Animals; Caffeine; Cricetinae; Disease Models, Animal; Dose-Response Relationship, Drug; Dystonia; Female; Male; Mesocricetus; Muscle Contraction; Mutation; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinazolines; Theobromine; Theophylline; Triazines; Triazoles; Xanthines	2001
Ca2+ sparks and secretion in dorsal root ganglion neurons. Proceedings of the National Academy of Sciences of the United States of America, 2005, Aug-23, Volume: 102, Issue:34 Topics: Animals; Caffeine; Calcitonin Gene-Related Peptide; Calcium; Endoplasmic Reticulum; Exocytosis; Ganglia, Spinal; Neurons, Afferent; Patch-Clamp Techniques; Rats; Ryanodine Receptor Calcium Release Channel; Signal Transduction; Theobromine	2005
Hypotensive effects of intravenously administered uridine and cytidine in conscious rats: involvement of adenosine receptors. European journal of pharmacology, 2008, Apr-14, Volume: 584, Issue:1 Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A2 Receptor Agonists; Animals; Antihypertensive Agents; Blood Pressure; Caffeine; Carotid Arteries; Consciousness; Cytidine; Dose-Response Relationship, Drug; Heart Rate; Hypotension; Injections, Intravenous; Injections, Intraventricular; Male; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptor, Adenosine A2A; Theobromine; Theophylline; Time Factors; Triazines; Triazoles; Uridine; Ventricular Function, Left; Ventricular Pressure; Xanthines	2008
Functional interaction between purinergic system and opioid withdrawal: in vitro evidence. Current drug safety, 2009, Volume: 4, Issue:2 Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenosine Triphosphate; Analgesics, Opioid; Animals; Caffeine; Dipyridamole; Dose-Response Relationship, Drug; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine; Morphine Dependence; Muscle, Smooth; Naloxone; Narcotic Antagonists; Narcotics; Phenethylamines; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Quinidine; Receptor, Adenosine A1; Receptors, Adenosine A2; Receptors, Purinergic P2; Substance Withdrawal Syndrome; Theobromine; Theophylline	2009
Hypoxia/reoxygenation impairs memory formation via adenosine-dependent activation of caspase 1. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012, Oct-03, Volume: 32, Issue:40 Topics: Adenosine; Amino Acid Chloromethyl Ketones; Amnesia, Anterograde; Amygdala; Animals; Caffeine; Caspase 1; Caspase Inhibitors; Conditioning, Classical; Cues; Enzyme Activation; Fear; Hypoxia, Brain; Interleukin 1 Receptor Antagonist Protein; Male; MAP Kinase Signaling System; Maze Learning; Mental Recall; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxygen; Receptors, Interleukin-1 Type I; Receptors, Purinergic P1; Recognition, Psychology; Theobromine; Xanthines	2012