3,7-dihydroxy-12-oxocholanoic acid has been researched along with methotrexate in 1 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (100.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Chen, G; Fawcett, JP; Mikov, M; Tucker, IG | 1 |
1 other study(ies) available for 3,7-dihydroxy-12-oxocholanoic acid and methotrexate
Article | Year |
---|---|
Monoketocholate can decrease transcellular permeation of methotrexate across Caco-2 cell monolayers and reduce its intestinal absorption in rat.
Topics: Adjuvants, Pharmaceutic; Administration, Oral; Animals; Area Under Curve; Biological Transport; Caco-2 Cells; Cell Membrane Permeability; Chenodeoxycholic Acid; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Humans; Immunosuppressive Agents; Intestinal Absorption; Male; Methotrexate; Rats; Rats, Wistar; Sodium Cholate | 2009 |