Page last updated: 2024-08-26

3,7-dihydroxy-12-oxocholanoic acid and methotrexate

3,7-dihydroxy-12-oxocholanoic acid has been researched along with methotrexate in 1 studies

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, G; Fawcett, JP; Mikov, M; Tucker, IG1

Other Studies

1 other study(ies) available for 3,7-dihydroxy-12-oxocholanoic acid and methotrexate

ArticleYear
Monoketocholate can decrease transcellular permeation of methotrexate across Caco-2 cell monolayers and reduce its intestinal absorption in rat.
    The Journal of pharmacy and pharmacology, 2009, Volume: 61, Issue:7

    Topics: Adjuvants, Pharmaceutic; Administration, Oral; Animals; Area Under Curve; Biological Transport; Caco-2 Cells; Cell Membrane Permeability; Chenodeoxycholic Acid; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Humans; Immunosuppressive Agents; Intestinal Absorption; Male; Methotrexate; Rats; Rats, Wistar; Sodium Cholate

2009