Page last updated: 2024-08-26

3,7-dihydroxy-12-oxocholanoic acid and chenodeoxycholic acid

3,7-dihydroxy-12-oxocholanoic acid has been researched along with chenodeoxycholic acid in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19905 (33.33)18.7374
1990's0 (0.00)18.2507
2000's3 (20.00)29.6817
2010's5 (33.33)24.3611
2020's2 (13.33)2.80

Authors

AuthorsStudies
Goto, J; Makino, I; Nambara, T; Sakuraba, K; Takebe, K; Tamasawa, N; Yoneda, M1
Akao, T; Hattori, M; Kobashi, K; Namba, T1
Codoceo, R; Diaz, C; Hernanz, A; Jara, P1
Gordon, SJ; Haeffner, LJ; Kowlessar, OD; Magen, JS1
Amuro, Y; Endo, T; Higashino, K; Uchida, K; Yamamura, Y1
Carrea, G; Fossati, E; Polentini, F; Riva, S1
Chen, G; Fawcett, JP; Mikov, M; Tucker, IG1
Csanádi, J; Guzsvány, V; Posa, M1
Al-Salami, H; Butt, G; Golocorbin-Kon, S; Mikov, M; Tucker, I1
Fawcett, JP; Tucker, IG; Yang, L; Zhang, H; Østergaard, J1
Hinow, P; Radunskaya, A; Tucker, I; Yang, L1
Fawcett, JP; Tucker, IG; Yang, L; Zhang, H1
Bojic, G; Djanic, M; Golocorbin-Kon, S; Mikov, M; Pavlovic, N; Stanimirov, B; Stojancevic, T1
Dan, J; Habuchi, H; Habuchi, O; Ikeuchi, M; Izumi, M; Takeuchi, K; Ushida, T1
Al-Salami, H; Golocorbin-Kon, S; Grujic-Letic, N; Mikov, M; Mooranian, A; Raškovic, A; Stilinovic, N; Teofilovic, B1

Other Studies

15 other study(ies) available for 3,7-dihydroxy-12-oxocholanoic acid and chenodeoxycholic acid

ArticleYear
The biotransformed metabolite profiles in blood after intravenous administration of dehydrocholic acid.
    The American journal of gastroenterology, 1989, Volume: 84, Issue:3

    Topics: Aged; Aged, 80 and over; Bile; Bile Acids and Salts; Chenodeoxycholic Acid; Common Bile Duct Neoplasms; Dehydrocholic Acid; Drainage; Humans; Injections, Intravenous; Male; Middle Aged

1989
Enzymes involved in the formation of 3 beta, 7 beta-dihydroxy-12-oxo-5 beta-cholanic acid from dehydrocholic acid by Ruminococcus sp. obtained from human intestine.
    Biochimica et biophysica acta, 1987, Sep-25, Volume: 921, Issue:2

    Topics: 3-Hydroxysteroid Dehydrogenases; Chenodeoxycholic Acid; Cholic Acids; Chromatography; Dehydrocholic Acid; Humans; Hydroxysteroid Dehydrogenases; Intestines; NADP; Peptococcaceae

1987
Unusual serum bile acid pattern in children with the syndrome of hepatic ductular hypoplasia.
    Clinica chimica acta; international journal of clinical chemistry, 1985, Feb-15, Volume: 145, Issue:3

    Topics: Bile Acids and Salts; Bile Ducts; Chenodeoxycholic Acid; Child; Child, Preschool; Cholestasis, Intrahepatic; Cholic Acid; Cholic Acids; Female; Humans; Infant; Male; Syndrome

1985
Evaluation of the 3 alpha-hydroxysteroid dehydrogenase assay for ursodeoxycholic acid, and 7 oxo- and 12 oxo- bile acids.
    Journal of lipid research, 1980, Volume: 21, Issue:4

    Topics: 3-Hydroxysteroid Dehydrogenases; Bile; Bile Acids and Salts; Chenodeoxycholic Acid; Cholic Acids; Chromatography, Gas; Deoxycholic Acid; Glycine; Humans; Intestines; Lithocholic Acid; Taurine; Ursodeoxycholic Acid

1980
Urinary and fecal keto bile acids in liver cirrhosis.
    Clinica chimica acta; international journal of clinical chemistry, 1981, Aug-10, Volume: 114, Issue:2-3

    Topics: Adult; Ascites; Bile Acids and Salts; Chenodeoxycholic Acid; Deoxycholic Acid; Esophageal and Gastric Varices; Feces; Hepatic Encephalopathy; Humans; Lithocholic Acid; Liver Cirrhosis; Male; Middle Aged

1981
Exploitation of the alcohol dehydrogenase-acetone NADP-regeneration system for the enzymatic preparative-scale production of 12-ketochenodeoxycholic acid.
    Biotechnology and bioengineering, 2006, Apr-20, Volume: 93, Issue:6

    Topics: Acetone; Alcohol Oxidoreductases; Bacteria; Biotechnology; Catalysis; Chenodeoxycholic Acid; Cholic Acid; Enzyme Stability; Hydroxysteroid Dehydrogenases; NADP; Substrate Specificity

2006
Monoketocholate can decrease transcellular permeation of methotrexate across Caco-2 cell monolayers and reduce its intestinal absorption in rat.
    The Journal of pharmacy and pharmacology, 2009, Volume: 61, Issue:7

    Topics: Adjuvants, Pharmaceutic; Administration, Oral; Animals; Area Under Curve; Biological Transport; Caco-2 Cells; Cell Membrane Permeability; Chenodeoxycholic Acid; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Humans; Immunosuppressive Agents; Intestinal Absorption; Male; Methotrexate; Rats; Rats, Wistar; Sodium Cholate

2009
Determination of critical micellar concentrations of two monoketo derivatives of cholic acid.
    Colloids and surfaces. B, Biointerfaces, 2009, Nov-01, Volume: 74, Issue:1

    Topics: Absorption; Bile Acids and Salts; Chenodeoxycholic Acid; Cholic Acid; Cholic Acids; Conductometry; Electric Conductivity; Hydrogen Bonding; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Micelles; Nitrazepam; Rhodamines; Sodium Chloride; Spectrophotometry; Urea

2009
Probiotics decreased the bioavailability of the bile acid analog, monoketocholic acid, when coadministered with gliclazide, in healthy but not diabetic rats.
    European journal of drug metabolism and pharmacokinetics, 2012, Volume: 37, Issue:2

    Topics: Administration, Oral; Animals; Biological Availability; Blood Glucose; Chenodeoxycholic Acid; Cholic Acids; Chromatography, High Pressure Liquid; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Drug Therapy, Combination; Food-Drug Interactions; Gliclazide; Hypoglycemic Agents; Injections, Intravenous; Male; Probiotics; Random Allocation; Rats; Rats, Wistar

2012
Mechanistic studies of the effect of bile salts on rhodamine 123 uptake into RBE4 cells.
    Molecular pharmaceutics, 2012, Jan-01, Volume: 9, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; Bile Acids and Salts; Biological Transport; Blood-Brain Barrier; Cell Line; Cell Membrane Permeability; Chenodeoxycholic Acid; Drug Compounding; Fluorescent Dyes; Kinetics; Liposomes; Membrane Fluidity; Membrane Transport Modulators; Models, Biological; Osmolar Concentration; Pharmaceutical Vehicles; Rats; Rhodamine 123; Surface Properties

2012
Kinetics of bile salt binding to liposomes revealed by carboxyfluorescein release and mathematical modeling.
    Journal of liposome research, 2012, Volume: 22, Issue:3

    Topics: Bile Acids and Salts; Biological Transport; Chenodeoxycholic Acid; Cholic Acids; Deoxycholic Acid; Fluoresceins; Kinetics; Lipid Bilayers; Liposomes; Models, Theoretical; Permeability; Time Factors

2012
Effect of 12-oxochenodeoxycholate on the pharmacokinetics and pharmacodynamics of morphine 6-glucuronide in Wistar rats.
    The Journal of pharmacy and pharmacology, 2013, Volume: 65, Issue:4

    Topics: Analgesics, Opioid; Animals; Blood-Brain Barrier; Brain; Chenodeoxycholic Acid; Dose-Response Relationship, Drug; Drug Synergism; Injections, Subcutaneous; Male; Membrane Transport Modulators; Metabolic Clearance Rate; Morphine Derivatives; Neurons; Pain Measurement; Permeability; Random Allocation; Rats; Rats, Wistar; Tissue Distribution

2013
Docking-based preliminary study on the interactions of bile acids with drugs at the transporter level in intestinal bacteria.
    European review for medical and pharmacological sciences, 2016, Volume: 20, Issue:3

    Topics: Bifidobacterium; Bile Acids and Salts; Carrier Proteins; Chenodeoxycholic Acid; Cholic Acid; Deoxycholic Acid; Lactobacillus acidophilus; Molecular Docking Simulation; Probiotics

2016
Bone marrow derived mast cells injected into the osteoarthritic knee joints of mice induced by sodium monoiodoacetate enhanced spontaneous pain through activation of PAR2 and action of extracellular ATP.
    PloS one, 2021, Volume: 16, Issue:6

    Topics: Adenosine Triphosphate; Animals; Arthritis, Experimental; Bone Marrow Cells; Chemokine CXCL2; Chenodeoxycholic Acid; Chronic Pain; Disease Models, Animal; Knee Joint; Male; Mast Cells; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Transgenic; Oligopeptides; Receptor, PAR-2; Receptors, Purinergic; Synovial Fluid

2021
Pharmacological effects of novel microvesicles of basil, on blood glucose and the lipid profile: a preclinical study.
    Scientific reports, 2021, 11-11, Volume: 11, Issue:1

    Topics: Alloxan; Animals; Blood Glucose; Chenodeoxycholic Acid; Diabetes Mellitus, Experimental; Hypoglycemic Agents; Lipids; Male; Microvessels; Ocimum basilicum; Plant Extracts; Rats; Rats, Wistar

2021