Page last updated: 2024-09-03

3,7,12-trihydroxycoprostanic acid and cholic acid

3,7,12-trihydroxycoprostanic acid has been researched along with cholic acid in 6 studies

Compound Research Comparison

Studies
(3,7,12-trihydroxycoprostanic acid)
Trials
(3,7,12-trihydroxycoprostanic acid)
Recent Studies (post-2010)
(3,7,12-trihydroxycoprostanic acid)
Studies
(cholic acid)
Trials
(cholic acid)
Recent Studies (post-2010) (cholic acid)
31001,92537530

Protein Interaction Comparison

ProteinTaxonomy3,7,12-trihydroxycoprostanic acid (IC50)cholic acid (IC50)
G-protein coupled bile acid receptor 1Mus musculus (house mouse)5.3
G-protein coupled bile acid receptor 1Homo sapiens (human)6

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19902 (33.33)18.7374
1990's4 (66.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hoshita, T; Imanaka, T; Izumi, N; Une, M1
Andersen, GI; Byström, SE; Farrants, AK1
Björkhem, I; Hågå, P; Kase, BF; Pedersen, JI1
Björkhem, I; Kase, BF; Pedersen, JI; Strandvik, B1
Busson, RH; Eyssen, HJ; Janssen, GA; Mannaerts, GP; Parmentier, GG1
Hoshita, T; Izumi, N; Une, M1

Other Studies

6 other study(ies) available for 3,7,12-trihydroxycoprostanic acid and cholic acid

ArticleYear
Formation of cholic acid from 3 alpha, 7 alpha, 12 alpha-trihydroxy-5 beta-cholestanoic acid in human skin fibroblasts.
    Journal of biochemistry, 1992, Volume: 112, Issue:5

    Topics: Catalase; Cells, Cultured; Cholic Acid; Cholic Acids; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Fibroblasts; Humans; Isomerism; Mitochondria; Skin

1992
Configuration of the 3 alpha,7 alpha,12 alpha-trihydroxy-5 beta-cholest-24-enoic acid, an intermediate in the peroxisomal conversion of 3 alpha,7 alpha,12-trihydroxy-5 beta-cholestanoic acid to cholic acid in rat liver.
    Biochemistry international, 1992, Volume: 26, Issue:4

    Topics: Animals; Cholesterol; Cholic Acid; Cholic Acids; In Vitro Techniques; Liver; Male; Microbodies; Molecular Conformation; Oxidoreductases; Rats; Rats, Inbred Strains

1992
Defective peroxisomal cleavage of the C27-steroid side chain in the cerebro-hepato-renal syndrome of Zellweger.
    The Journal of clinical investigation, 1985, Volume: 75, Issue:2

    Topics: Bile; Bile Acids and Salts; Cholic Acid; Cholic Acids; Female; Humans; Infant, Newborn; Kidney Diseases; Liver; Liver Diseases; Microbodies; Syndrome

1985
In vivo and vitro studies on formation of bile acids in patients with Zellweger syndrome. Evidence that peroxisomes are of importance in the normal biosynthesis of both cholic and chenodeoxycholic acid.
    The Journal of clinical investigation, 1985, Volume: 76, Issue:6

    Topics: Bile Acids and Salts; Chenodeoxycholic Acid; Cholestenones; Cholic Acid; Cholic Acids; Humans; Kinetics; Liver Diseases; Metabolic Clearance Rate; Microbodies; Subcellular Fractions; Syndrome

1985
Synthesis and 29-14C-labeling of 3 alpha, 7 alpha, 12 alpha-trihydroxy-27-carboxymethyl-5 beta-cholestan-26-oic acid. A bile acid occurring in peroxisomal diseases.
    Steroids, 1993, Volume: 58, Issue:8

    Topics: Aldehydes; Carbon Radioisotopes; Cholic Acid; Cholic Acids; Esterification; Humans; Hydrolysis; Isotope Labeling; Magnetic Resonance Spectroscopy; Malonates; Mesylates; Microbodies; Molecular Structure; Zellweger Syndrome

1993
Stereochemistry of intermediates in the conversion of 3 alpha,7 alpha,12 alpha-trihydroxy-5 beta-cholestanoic acid to cholic acid by rat liver peroxisomes.
    Journal of biochemistry, 1993, Volume: 113, Issue:2

    Topics: Animals; Cholic Acid; Cholic Acids; In Vitro Techniques; Liver; Male; Microbodies; Rats; Rats, Wistar; Stereoisomerism

1993