3,7,12-trihydroxycholestan-26-oic acid has been researched along with cholic acid in 7 studies
| Studies (3,7,12-trihydroxycholestan-26-oic acid) | Trials (3,7,12-trihydroxycholestan-26-oic acid) | Recent Studies (post-2010) (3,7,12-trihydroxycholestan-26-oic acid) | Studies (cholic acid) | Trials (cholic acid) | Recent Studies (post-2010) (cholic acid) |
|---|---|---|---|---|---|
| 31 | 0 | 0 | 1,925 | 37 | 530 |
| Protein | Taxonomy | 3,7,12-trihydroxycholestan-26-oic acid (IC50) | cholic acid (IC50) |
|---|---|---|---|
| G-protein coupled bile acid receptor 1 | Mus musculus (house mouse) | 5.3 | |
| G-protein coupled bile acid receptor 1 | Homo sapiens (human) | 6 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (57.14) | 18.7374 |
| 1990's | 3 (42.86) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Björkhem, I; Ostlund Farrants, AK; Pedersen, JI | 2 |
| Poulos, A; Whiting, MJ | 1 |
| Everson, GT; Polokoff, MA | 1 |
| Björkhem, I; Kase, BF; Pedersen, JI; Prydz, K | 1 |
| Fujimoto, Y; Hagiwara, C; Kobayashi, N; Morisaki, M; Oya, I; Yuri, M | 1 |
| Farrants, AK; Nilsson, A; Pedersen, JI | 1 |
7 other study(ies) available for 3,7,12-trihydroxycholestan-26-oic acid and cholic acid
| Article | Year |
|---|---|
Differential induction of peroxisomal oxidation of palmitic acid and 3 alpha,7 alpha,12 alpha-trihydroxy-5 beta-cholestanoic acid in rat liver.
Topics: Acyl-CoA Oxidase; Animals; Cholestanols; Cholic Acid; Cholic Acids; Clofibrate; Dietary Fats; Fish Oils; Male; Microbodies; Mitochondria, Liver; Oxidation-Reduction; Oxidoreductases; Palmitic Acid; Palmitic Acids; Rats; Rats, Inbred Strains; Soybean Oil | 1990 |
Identification of 3 alpha,7 alpha,12 alpha-trihydroxy-5 beta-cholestan-26-oic acid, an intermediate in cholic acid synthesis, in the plasma of patients with infantile Refsum's disease.
Topics: Bile Acids and Salts; Cholestanols; Cholic Acid; Cholic Acids; Chromatography, Gas; Fatty Acids; Humans; Mass Spectrometry; Metabolism, Inborn Errors; Pipecolic Acids; Refsum Disease | 1985 |
Identification of 3 alpha, 7 alpha, 12 alpha-trihydroxy-5 beta-cholest-24-enoic acid as an intermediate in the peroxisomal conversion of 3 alpha,7 alpha,12 alpha-trihydroxy-5 beta-cholestanoic acid to cholic acid.
Topics: Adenosine Triphosphate; Animals; Cholestanols; Cholesterol; Cholic Acid; Cholic Acids; Chromatography, High Pressure Liquid; Coenzyme A; Gas Chromatography-Mass Spectrometry; Liver; Magnesium; Male; Microbodies; NAD; Rats; Rats, Inbred Strains | 1989 |
HepG2. A human hepatoblastoma cell line exhibiting defects in bile acid synthesis and conjugation.
Topics: Bile Acids and Salts; Carcinoma, Hepatocellular; Cell Line; Chenodeoxycholic Acid; Cholestanols; Cholic Acid; Cholic Acids; Gas Chromatography-Mass Spectrometry; Humans; Liver Neoplasms | 1986 |
Formation of chenodeoxycholic acid from 3 alpha, 7 alpha-dihydroxy-5 beta-cholestanoic acid by rat liver peroxisomes.
Topics: Animals; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestanols; Cholic Acid; Cholic Acids; In Vitro Techniques; Liver; Male; Microbodies; Oxidation-Reduction; Rats; Rats, Inbred Strains; Subcellular Fractions | 1986 |
Non-stereoselective formation of 3 alpha,7 alpha,12 alpha,24-tetrahydroxy-5 beta-cholestan-26-oic acid during cholic acid biosynthesis.
Topics: Animals; Cholestanols; Cholesterol; Cholic Acid; Cholic Acids; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Male; Mitochondria, Liver; Rats; Rats, Wistar; Stereoisomerism | 1994 |
Human hepatoblastoma cells (HepG2) and rat hepatoma cells are defective in important enzyme activities in the oxidation of the C27 steroid side chain in bile acid formation.
Topics: Animals; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestanols; Cholesterol 7-alpha-Hydroxylase; Cholic Acid; Cholic Acids; Clofibric Acid; Dexamethasone; Fatty Acids; Hepatoblastoma; Humans; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Oxidation-Reduction; Rats; Rats, Wistar; Retinoids; Tumor Cells, Cultured | 1993 |