Page last updated: 2024-09-03

3,7,12-trihydroxycholestan-26-oic acid and 3,7-dihydroxycholestan-26-oic acid

3,7,12-trihydroxycholestan-26-oic acid has been researched along with 3,7-dihydroxycholestan-26-oic acid in 14 studies

Compound Research Comparison

Studies
(3,7,12-trihydroxycholestan-26-oic acid)
Trials
(3,7,12-trihydroxycholestan-26-oic acid)
Recent Studies (post-2010)
(3,7,12-trihydroxycholestan-26-oic acid)
Studies
(3,7-dihydroxycholestan-26-oic acid)
Trials
(3,7-dihydroxycholestan-26-oic acid)
Recent Studies (post-2010) (3,7-dihydroxycholestan-26-oic acid)
31002100

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19904 (28.57)18.7374
1990's7 (50.00)18.2507
2000's3 (21.43)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Batta, AK; Mirchandani, R; Salen, G; Shefer, S1
Jakobs, C; Kleijer, WJ; Schutgens, RB; Stellaard, F; Wanders, RJ1
Casteels, M; Hyanek, J; Kozich, V; Mannaerts, GP; Schutgens, RB; van Roermund, CW; Wanders, RJ; Zeman, J1
Arora, R; Batta, AK; Batta, M; Salen, G; Shefer, S1
Goto, J; Miura, H; Nambara, T1
Everson, GT; Polokoff, MA1
Björkhem, I; Kase, BF; Pedersen, JI; Prydz, K1
Cass, OW; Hanson, RF; Williams, GC1
Kurosawa, T; Nakano, H; Sato, M; Tohma, M1
Brandt, NJ; Christensen, E; Jakobs, C; ten Brink, HJ; Wanders, RJ1
Farrants, AK; Nilsson, A; Pedersen, JI1
Jas, G; Kalvinsh, I; Kauss, V; Starchenkov, I; Trapencieris, P1
Jakobs, C; Johnson, DW; Schuit, RC; ten Brink, HJ1
Denis, S; Ferdinandusse, S; Overmars, H; Vreken, P; Wanders, RJ; Waterham, HR1

Other Studies

14 other study(ies) available for 3,7,12-trihydroxycholestan-26-oic acid and 3,7-dihydroxycholestan-26-oic acid

ArticleYear
Synthesis of 3 alpha, 7 alpha-dihydroxy-5 beta-cholestan-26-oic acid from 3 alpha,7 alpha,12 alpha-trihydroxy-5 beta-cholestan-26-oic acid: configuration in the bile of Alligator mississippiensis.
    Steroids, 1992, Volume: 57, Issue:4

    Topics: Acetylation; Alligators and Crocodiles; Animals; Bile; Cholestanols; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Gas Chromatography-Mass Spectrometry; Magnetic Resonance Spectroscopy; Stereoisomerism

1992
Bile acids in amniotic fluid: promising metabolites for the prenatal diagnosis of peroxisomal disorders.
    Journal of inherited metabolic disease, 1991, Volume: 14, Issue:3

    Topics: Amniotic Fluid; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestanols; Cholic Acids; Female; Fetus; Humans; Metabolism, Inborn Errors; Microbodies; Pregnancy; Prenatal Diagnosis

1991
Accumulation and impaired in vivo metabolism of di- and trihydroxycholestanoic acid in two patients.
    Clinica chimica acta; international journal of clinical chemistry, 1991, Oct-31, Volume: 202, Issue:3

    Topics: Abnormalities, Multiple; Acyl Coenzyme A; Bile Acids and Salts; Cells, Cultured; Cholestanols; Coenzyme A Ligases; Dicarboxylic Acids; Diseases in Twins; Fatty Acids, Nonesterified; Female; Fibroblasts; Humans; Infant; Liver; Microbodies; Palmitoyl Coenzyme A; Phenotype; Repressor Proteins; Saccharomyces cerevisiae Proteins; Skin; Twins, Dizygotic; Zellweger Syndrome

1991
High-performance liquid chromatographic separation of bile acids and bile alcohols diastereoisomeric at C-25.
    Journal of chromatography, 1991, Mar-29, Volume: 542, Issue:1

    Topics: Alligators and Crocodiles; Animals; Bile; Bile Acids and Salts; Cholestanols; Chromatography, High Pressure Liquid; Stereoisomerism

1991
Studies on steroids. CCXXXXV. Determination of 5 beta-cholestanoic acids in human urine by gas chromatography-mass spectrometry with negative ion chemical ionization detection.
    Journal of chromatography, 1989, Sep-01, Volume: 493, Issue:2

    Topics: Bile Acids and Salts; Cholestanols; Gas Chromatography-Mass Spectrometry; Humans; Hydrolysis; Steroids

1989
HepG2. A human hepatoblastoma cell line exhibiting defects in bile acid synthesis and conjugation.
    The Journal of biological chemistry, 1986, Feb-15, Volume: 261, Issue:5

    Topics: Bile Acids and Salts; Carcinoma, Hepatocellular; Cell Line; Chenodeoxycholic Acid; Cholestanols; Cholic Acid; Cholic Acids; Gas Chromatography-Mass Spectrometry; Humans; Liver Neoplasms

1986
Formation of chenodeoxycholic acid from 3 alpha, 7 alpha-dihydroxy-5 beta-cholestanoic acid by rat liver peroxisomes.
    Journal of lipid research, 1986, Volume: 27, Issue:6

    Topics: Animals; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestanols; Cholic Acid; Cholic Acids; In Vitro Techniques; Liver; Male; Microbodies; Oxidation-Reduction; Rats; Rats, Inbred Strains; Subcellular Fractions

1986
Competitive inhibition of side chain oxidation of 3 alpha, 7 alpha-dihydroxy-5 beta-cholestan-26-oic acid by 3 alpha, 7 alpha, 12 alpha-trihydroxy-5 beta-cholestan-26-oic acid in the hamster.
    Journal of lipid research, 1980, Volume: 21, Issue:2

    Topics: Animals; Bile; Binding, Competitive; Chenodeoxycholic Acid; Cholestanols; Cholic Acids; Cricetinae; Isotope Labeling; Male; Mesocricetus; Tritium

1980
Synthesis of 3 alpha, 7 alpha, 12 alpha-trihydroxy- and 3 alpha, 7 alpha-dihydroxy-5 beta-cholestan-26-oic acids by the use of beta-ketosulfoxide.
    Steroids, 1995, Volume: 60, Issue:7

    Topics: Chenodeoxycholic Acid; Cholates; Cholestanols; Cholic Acids; Indicators and Reagents; Ketones; Magnetic Resonance Spectroscopy; Sulfoxides

1995
Heterogeneity in di/trihydroxycholestanoic acidaemia.
    Annals of clinical biochemistry, 1994, Volume: 31 ( Pt 2)

    Topics: Cholestanols; Fatty Acids; Humans; Oxidoreductases; Phytanic Acid

1994
Human hepatoblastoma cells (HepG2) and rat hepatoma cells are defective in important enzyme activities in the oxidation of the C27 steroid side chain in bile acid formation.
    Journal of lipid research, 1993, Volume: 34, Issue:12

    Topics: Animals; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestanols; Cholesterol 7-alpha-Hydroxylase; Cholic Acid; Cholic Acids; Clofibric Acid; Dexamethasone; Fatty Acids; Hepatoblastoma; Humans; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Oxidation-Reduction; Rats; Rats, Wistar; Retinoids; Tumor Cells, Cultured

1993
A convenient synthesis of 5beta-cholestan-26-oic and 5beta-cholestan-26,27-dioic acids.
    Steroids, 2000, Volume: 65, Issue:3

    Topics: Cholestanols

2000
Rapid and quantitative analysis of unconjugated C(27) bile acids in plasma and blood samples by tandem mass spectrometry.
    Journal of lipid research, 2001, Volume: 42, Issue:1

    Topics: Age Factors; Bile Acids and Salts; Child; Child, Preschool; Cholestanols; Deuterium; Fatty Acids; Humans; Infant; Infant, Newborn; Matched-Pair Analysis; Peroxisomal Disorders; Spectrometry, Mass, Electrospray Ionization

2001
Plasma analysis of di- and trihydroxycholestanoic acid diastereoisomers in peroxisomal alpha-methylacyl-CoA racemase deficiency.
    Journal of lipid research, 2001, Volume: 42, Issue:1

    Topics: Bile Acids and Salts; Child, Preschool; Cholestanols; Cholestasis, Intrahepatic; Diagnosis, Differential; Female; Humans; Infant; Male; Oxidation-Reduction; Peroxisomal Disorders; Peroxisomes; Racemases and Epimerases; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism; Zellweger Syndrome

2001