Compounds > 3,6-bis(5-chloro-2-piperidyl)-2,5-piperazinedione
Page last updated: 2024-09-02

3,6-bis(5-chloro-2-piperidyl)-2,5-piperazinedione and dacarbazine

3,6-bis(5-chloro-2-piperidyl)-2,5-piperazinedione has been researched along with dacarbazine in 3 studies

Compound Research Comparison

Studies
(3,6-bis(5-chloro-2-piperidyl)-2,5-piperazinedione)		Trials
(3,6-bis(5-chloro-2-piperidyl)-2,5-piperazinedione)		Recent Studies (post-2010)
(3,6-bis(5-chloro-2-piperidyl)-2,5-piperazinedione)		Studies
(dacarbazine)		Trials
(dacarbazine)		Recent Studies (post-2010) (dacarbazine)
49787,5561,4633,429

Protein Interaction Comparison

ProteinTaxonomy3,6-bis(5-chloro-2-piperidyl)-2,5-piperazinedione (IC50)dacarbazine (IC50)
Matrix metalloproteinase-9Homo sapiens (human)0.556

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19902 (66.67)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Klahr, C; Presant, CA1
Balch, C; Bartolucci, AA; Presant, CA; Troner, M1

Trials

1 trial(s) available for 3,6-bis(5-chloro-2-piperidyl)-2,5-piperazinedione and dacarbazine

ArticleYear
A randomized comparison of cyclophosphamide, DTIC with or without piperazinedione in metastatic malignant melanoma.
    Cancer, 1982, Apr-01, Volume: 49, Issue:7

    Topics: Antibiotics, Antineoplastic; Clinical Trials as Topic; Cyclophosphamide; Dacarbazine; Drug Therapy, Combination; Female; Humans; Male; Melanoma; Piperazines; Random Allocation; Skin Neoplasms

1982

Other Studies

2 other study(ies) available for 3,6-bis(5-chloro-2-piperidyl)-2,5-piperazinedione and dacarbazine

ArticleYear
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Severe myelosuppression from piperazinedione, (NSC No. 135758), cyclophosphamide plus dimethyl-triazeno-imidazole carboxamide (DTIC).
    Cancer, 1977, Volume: 40, Issue:4

    Topics: Bone Marrow; Cyclophosphamide; Dacarbazine; Drug Therapy, Combination; Humans; Neoplasms; Piperazines; Piperidines; Triazenes

1977