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3,6-bis(2-(diethylamino)ethoxy)acridine and tilorone

3,6-bis(2-(diethylamino)ethoxy)acridine has been researched along with tilorone in 5 studies

*Tilorone: An antiviral agent used as its hydrochloride. It is the first recognized synthetic, low-molecular-weight compound that is an orally active interferon inducer, and is also reported to have antineoplastic and anti-inflammatory actions. [MeSH]

*Tilorone: An antiviral agent used as its hydrochloride. It is the first recognized synthetic, low-molecular-weight compound that is an orally active interferon inducer, and is also reported to have antineoplastic and anti-inflammatory actions. [MeSH]

Compound Research Comparison

Studies
(3,6-bis(2-(diethylamino)ethoxy)acridine)
Trials
(3,6-bis(2-(diethylamino)ethoxy)acridine)
Recent Studies (post-2010)
(3,6-bis(2-(diethylamino)ethoxy)acridine)
Studies
(tilorone)
Trials
(tilorone)
Recent Studies (post-2010) (tilorone)
6003691250

Protein Interaction Comparison

ProteinTaxonomy3,6-bis(2-(diethylamino)ethoxy)acridine (IC50)tilorone (IC50)
cystic fibrosis transmembrane conductance regulatorHomo sapiens (human)30.25
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 24.09
DNA primaseMycobacterium tuberculosis CDC15517.1

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Handrock, K; Laschke, A; Lüllmann-Rauch, R; Vogt, RD; Ziegenhagen, M1
Grave, S; Lüllmann, H; Lüllmann-Rauch, R; Osterkamp, G; Prokopek, M1
Lüllmann-Rauch, R1
Fischer, J1
Bispinck, F; Fischer, J; Lüllmann-Rauch, R; von Witzendorff, B1

Other Studies

5 other study(ies) available for 3,6-bis(2-(diethylamino)ethoxy)acridine and tilorone

ArticleYear
Lysosomal storage of sulfated glycosaminoglycans in cultured fibroblasts exposed to immunostimulatory acridine derivatives.
    Toxicology and applied pharmacology, 1992, Volume: 114, Issue:2

    Topics: Acridines; Adjuvants, Immunologic; Animals; Cattle; Cells, Cultured; Cornea; Fibroblasts; Glycosaminoglycans; Intracellular Fluid; Kinetics; Lysosomes; Microscopy, Electron; Rats; Species Specificity; Sulfur Radioisotopes; Tilorone

1992
Induction of mucopolysaccharidosis in rats by treatment with immunostimulatory acridine derivatives.
    Toxicology and applied pharmacology, 1992, Volume: 114, Issue:2

    Topics: Acridines; Adjuvants, Immunologic; Animals; Female; Glycosaminoglycans; Liver; Lysosomes; Mucopolysaccharidoses; Rats; Rats, Inbred Strains; Spleen; Tilorone

1992
Drug-induced intralysosomal storage of sulfated glycosaminoglycans (GAGs): a methodical pitfall occurring with acridine derivatives.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 1994, Volume: 46, Issue:4-5

    Topics: Acridines; Adjuvants, Immunologic; Animals; Cells, Cultured; Fibroblasts; Glycosaminoglycans; Histocytochemistry; Liver; Lymph Nodes; Lysosomal Storage Diseases; Lysosomes; Microscopy, Electron; Microscopy, Fluorescence; Rats; Spleen; Tilorone; Tissue Fixation

1994
Drug-induced glycosaminoglycan storage: dose-dependent changes in the pattern of accumulated glycosaminoglycans in cultured bovine and human fibroblasts.
    Biochemical pharmacology, 1996, Nov-08, Volume: 52, Issue:9

    Topics: Acridines; Adjuvants, Immunologic; Animals; Anthraquinones; Cattle; Cells, Cultured; Dermatan Sulfate; Dose-Response Relationship, Drug; Extracellular Space; Fibroblasts; Fluorenes; Glycosaminoglycans; Humans; Intracellular Fluid; Tilorone

1996
Lysosomal glycosaminoglycan storage as induced by dicationic amphiphilic drugs: investigation into the mechanisms underlying the slow reversibility.
    Toxicology, 1998, Jul-03, Volume: 128, Issue:2

    Topics: Acridines; Adjuvants, Immunologic; Animals; beta-N-Acetylhexosaminidases; Cattle; Cells, Cultured; Dermatan Sulfate; Dose-Response Relationship, Drug; Fibroblasts; Glycosaminoglycans; Heparitin Sulfate; Immunohistochemistry; Lysosomes; Tilorone

1998