Page last updated: 2024-09-04

3,5-dimethoxy-4'-hydroxystilbene and pterostilbene

3,5-dimethoxy-4'-hydroxystilbene has been researched along with pterostilbene in 24 studies

Compound Research Comparison

Studies
(3,5-dimethoxy-4'-hydroxystilbene)
Trials
(3,5-dimethoxy-4'-hydroxystilbene)
Recent Studies (post-2010)
(3,5-dimethoxy-4'-hydroxystilbene)
Studies
(pterostilbene)
Trials
(pterostilbene)
Recent Studies (post-2010) (pterostilbene)
250245498480

Protein Interaction Comparison

ProteinTaxonomy3,5-dimethoxy-4'-hydroxystilbene (IC50)pterostilbene (IC50)
Tyrosine-protein kinase ABL1Homo sapiens (human)10
Neuronal acetylcholine receptor subunit alpha-4Rattus norvegicus (Norway rat)0.82
Polyunsaturated fatty acid 5-lipoxygenaseHomo sapiens (human)4.5867
Breakpoint cluster region proteinHomo sapiens (human)10
Neuronal acetylcholine receptor subunit beta-2Rattus norvegicus (Norway rat)0.82
Ribosyldihydronicotinamide dehydrogenase [quinone]Homo sapiens (human)5.1
Prostaglandin G/H synthase 1Homo sapiens (human)0.7
Prostaglandin G/H synthase 2Homo sapiens (human)0.82
Transient receptor potential cation channel subfamily A member 1Rattus norvegicus (Norway rat)7.5

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's24 (100.00)2.80

Authors

AuthorsStudies
Capcarova, M; Fernandez-Cruz, ML; Greifova, H; Spevakova, I; Tokarova, K1
Chen, H; Chen, J; Chen, X; Han, L; Huang, H; Li, Y; Sun, C; Zhang, Y1
Li, S; Wang, H; Zhou, Y1
Gu, Q; Han, JR; Li, P; Wang, Q; Wu, HT; Xiao, H; Yi, LX; Zhu, BW1
An, X; Lv, J; Wang, F1
Cao, Q; Li, M; Liu, L; Wang, C; Wu, X; Yuan, Z; Zhou, L1
Abbas, G; Akhtar, MF; Amin, A; Anwar, F; Khan, MI; Saleem, A; Shah, S; Sharif, A; Sohail, MF; Zubair, HM1
Ashcroft, SP; Damgaard, MV; Holst, JJ; Jepsen, SL; Treebak, JT1
Chen, Y; Ji, S; Jia, P; Li, Y; Wang, T; Zhang, H1
Ganesan, K; Mohandas, S; Nagarajan, S; Ramkumar, KM; Xu, B1
Cao, J; Chen, Y; Hou, X; Li, Y; Tu, F; Yan, J; Zhang, H1
Chen, J; Deng, C; He, J; He, S; Hu, Y; Qu, H; Zhang, H; Zhang, L; Zhong, H1
Ding, F; Fang, J; Lu, Y; Zhang, Z; Zhao, X; Zhou, G; Zhou, J; Zhuang, Z1
Chen, X; Han, L; Huang, H; Li, Y; Sun, C; Xing, H; Zhang, Y; Zhao, D1
Fernández-Quintela, A; Hernández, F; Izquierdo-Sandoval, D; Lacalle-Bergeron, L; Portillo, MP; Portolés, T; Sancho, JV1
Hou, P; Jing, J; Mi, M; Wang, L; Wu, L; Yi, L; Zheng, L; Zhou, M; Zhu, J1
Gołąbek-Grenda, A; Juzwa, W; Kaczmarek, M; Olejnik, A1
Ban, W; Huang, J; Jiang, X; Jiao, Y; Lv, L; Yang, Z; You, Y1
Ban, WK; Chen, X; Hou, ZY; Liu, AL; Liu, HB; Liu, YJ; Lu, J; Lv, LJ; Yang, ZH; You, YY; Zhang, BY1
Cheng, H; Hu, Q; Li, Y; Luo, J; Wang, X; Wu, J; Wu, Y; Yu, J; Zhang, G; Zhang, Q1
Gao, Y; Gu, C; Jin, Q; Li, J; Ma, W; Wang, C; Wu, X1
Li, L; Liu, Q; Wei, G; Yu, Y1
Qu, X; Wang, L; Zhang, L1
Chen, Y; Duan, Y; Fang, M; Jiang, M; Li, Q; Lv, Z; Ma, C; Shen, Z; Wang, S; Wei, X; Yang, X; Zhang, B; Zhang, T; Zhu, M1

Reviews

2 review(s) available for 3,5-dimethoxy-4'-hydroxystilbene and pterostilbene

ArticleYear
New Insights into Dietary Pterostilbene: Sources, Metabolism, and Health Promotion Effects.
    Molecules (Basel, Switzerland), 2022, Sep-25, Volume: 27, Issue:19

    Topics: Antioxidants; Health Promotion; Humans; NF-E2-Related Factor 2; Resveratrol; Stilbenes

2022
Pterostilbene as a Therapeutic Alternative for Central Nervous System Disorders: A Review of the Current Status and Perspectives.
    Journal of agricultural and food chemistry, 2023, Oct-11, Volume: 71, Issue:40

    Topics: Animals; Central Nervous System Diseases; Glioma; Humans; NF-kappa B; Signal Transduction; Stilbenes

2023

Other Studies

22 other study(ies) available for 3,5-dimethoxy-4'-hydroxystilbene and pterostilbene

ArticleYear
The protective effect of stilbenes resveratrol and pterostilbene individually and combined with mycotoxin citrinin in human adenocarcinoma HT-29 cell line
    Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering, 2021, Volume: 56, Issue:1

    Topics: Antioxidants; Apoptosis; Cell Membrane; Cell Survival; Citrinin; Dose-Response Relationship, Drug; Drug Interactions; HT29 Cells; Humans; Oxidative Stress; Resveratrol; Stilbenes

2021
Subacute oral toxicology and toxicokinetics of pterostilbene, a novel Top1/Tdp1 inhibiting anti-tumor reagent.
    Drug and chemical toxicology, 2023, Volume: 46, Issue:2

    Topics: Animals; Chromatography, Liquid; Female; Male; Neoplasms; Rats; Tandem Mass Spectrometry; Toxicokinetics

2023
JAK2/STAT3 pathway mediates beneficial effects of pterostilbene on cardiac contractile and electrical function in the setting of myocardial reperfusion injury.
    Physiological research, 2022, Aug-31, Volume: 71, Issue:4

    Topics: Animals; Apoptosis; Cytokines; Glutathione; Inflammation Mediators; Interleukin-1; Janus Kinase 2; Male; Manganese; Myocardial Infarction; Myocardial Reperfusion Injury; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Reperfusion Injury; Stilbenes; Superoxide Dismutase

2022
Improving the
    Food & function, 2022, Sep-22, Volume: 13, Issue:18

    Topics: Animals; Biological Availability; Caco-2 Cells; Catechin; Corn Oil; Delayed-Action Preparations; Emulsions; Excipients; Gonads; Humans; Mice; Micelles; Oils; Pectinidae; Proteins; Stilbenes

2022
Pterostilbene inhibits melanogenesis, melanocyte dendricity and melanosome transport through cAMP/PKA/CREB pathway.
    European journal of pharmacology, 2022, Oct-15, Volume: 932

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Cell Line, Tumor; Humans; Melanins; Melanocytes; Melanosomes; Microphthalmia-Associated Transcription Factor; Monophenol Monooxygenase; Stilbenes; Zebrafish

2022
Novel pterostilbene-loaded pro-phytomicelles: preclinical pharmacokinetics, distribution, and treatment efficacy against acetaminophen-induced liver injury.
    Food & function, 2022, Oct-03, Volume: 13, Issue:19

    Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury, Chronic; Cytokines; HMGB1 Protein; Liver; Mice; Rats; Stilbenes; Treatment Outcome

2022
Pterostilbene improves CFA-induced arthritis and peripheral neuropathy through modulation of oxidative stress, inflammatory cytokines and neurotransmitters in Wistar rats.
    Inflammopharmacology, 2022, Volume: 30, Issue:6

    Topics: Analgesics; Animals; Arthritis, Experimental; Cytokines; Freund's Adjuvant; Neurotransmitter Agents; Nitrites; Oxidative Stress; Peripheral Nervous System Diseases; Rats; Rats, Wistar; Stilbenes; Superoxide Dismutase

2022
Pterostilbene Fails to Rescue Insulin Secretion and Sensitivity in Multiple Murine Models of Diabetes.
    Nutrients, 2022, Sep-10, Volume: 14, Issue:18

    Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Disease Models, Animal; Glucose; Insulin; Insulin Secretion; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Rats; Stilbenes; Streptozocin

2022
Pterostilbene Prevents Tunicamycin-Induced Intestinal Barrier Damage by Targeting Endoplasmic Reticulum Stress, Oxidative Stress, Autophagy, and Gut Microbiota.
    Journal of agricultural and food chemistry, 2022, Oct-26, Volume: 70, Issue:42

    Topics: Animals; Apoptosis; Autophagy; Endoplasmic Reticulum Stress; Gastrointestinal Microbiome; Oxidative Stress; Sirtuin 1; Swine; Tunicamycin

2022
Effects of resveratrol and its derivative pterostilbene on hepatic injury and immunological stress of weaned piglets challenged with lipopolysaccharide.
    Journal of animal science, 2022, Dec-01, Volume: 100, Issue:12

    Topics: Animals; Lipopolysaccharides; Liver; NF-kappa B; Resveratrol; Swine; Weaning

2022
Self-assembled micelle derived from pterostilbene ameliorate acute inflammatory bowel disease.
    International journal of pharmaceutics, 2023, Jan-05, Volume: 630

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Inflammatory Bowel Diseases; Mice; Micelles; NF-kappa B; Signal Transduction; Toll-Like Receptor 4

2023
Pterostilbene Attenuates Subarachnoid Hemorrhage-Induced Brain Injury through the SIRT1-Dependent Nrf2 Signaling Pathway.
    Oxidative medicine and cellular longevity, 2022, Volume: 2022

    Topics: Apoptosis; Brain Injuries; Humans; NF-E2-Related Factor 2; Oxidative Stress; Signal Transduction; Sirtuin 1; Subarachnoid Hemorrhage

2022
Phase I Metabolism of Pterostilbene, a Dietary Resveratrol Derivative: Metabolite Identification, Species Differences, Isozyme Contribution, and Further Bioactivation.
    Journal of agricultural and food chemistry, 2023, Jan-11, Volume: 71, Issue:1

    Topics: Glutathione; Humans; Isoenzymes; Quinones; Resveratrol; Species Specificity

2023
LC-IMS-HRMS for identification of biomarkers in untargeted metabolomics: The effects of pterostilbene and resveratrol consumption in liver steatosis, animal model.
    Food research international (Ottawa, Ont.), 2023, Volume: 165

    Topics: Animals; Biomarkers; Fatty Liver; Models, Animal; Rats; Rats, Wistar; Resveratrol

2023
Pterostilbene Attenuates High-Intensity Swimming Exercise-Induced Glucose Absorption Dysfunction Associated with the Inhibition of NLRP3 Inflammasome-Induced IECs Pyroptosis.
    Nutrients, 2023, Apr-23, Volume: 15, Issue:9

    Topics: Animals; Glucose; Inflammasomes; Intestines; Male; Mice; Mice, Inbred C57BL; NLR Family, Pyrin Domain-Containing 3 Protein; Pyroptosis; Reactive Oxygen Species; Swimming

2023
Natural resveratrol analogs differentially target endometriotic cells into apoptosis pathways.
    Scientific reports, 2023, 07-15, Volume: 13, Issue:1

    Topics: Apoptosis; Endometriosis; Endometrium; Female; Humans; Resveratrol; Stromal Cells

2023
Illustrate the distribution and metabolic regulatory effects of pterostilbene in cerebral ischemia-reperfusion rat brain by mass spectrometry imaging and spatial metabolomics.
    Talanta, 2024, Jan-01, Volume: 266, Issue:Pt 2

    Topics: Animals; Brain; Brain Ischemia; Ischemic Stroke; Metabolomics; Rats; Reperfusion; Spectrometry, Mass, Electrospray Ionization

2024
Pterostilbene alleviated cerebral ischemia/reperfusion-induced blood-brain barrier dysfunction
    Food & function, 2023, Sep-19, Volume: 14, Issue:18

    Topics: Basement Membrane; Blood-Brain Barrier; Cerebral Infarction; Humans; Ischemia; Matrix Metalloproteinase 9; Molecular Docking Simulation; Reperfusion; Reperfusion Injury; Stroke

2023
Pterostilbene attenuates microglial inflammation and brain injury after intracerebral hemorrhage in an OPA1-dependent manner.
    Frontiers in immunology, 2023, Volume: 14

    Topics: Animals; Brain Edema; Brain Injuries; Cerebral Hemorrhage; Inflammation; Mice; Microglia; Neuroinflammatory Diseases

2023
Drug-Loaded Konjac Glucomannan/Metal-Organic Framework Composite Hydrogels as Antibacterial and Anti-Inflammatory Cell Scaffolds.
    ACS applied materials & interfaces, 2023, Sep-06, Volume: 15, Issue:35

    Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents; Humans; Hydrogels; Metal-Organic Frameworks

2023
Elucidating the Mechanisms of R248Q Mutation-Enhanced p53 Aggregation and Its Inhibition by Resveratrol.
    The journal of physical chemistry. B, 2023, 09-14, Volume: 127, Issue:36

    Topics: Mutation; Resveratrol; Tumor Suppressor Protein p53

2023
The pterostilbene-dihydropyrazole derivative Ptd-1 ameliorates vascular calcification by regulating inflammation.
    International immunopharmacology, 2023, Volume: 125, Issue:Pt B

    Topics: Animals; Atherosclerosis; beta Catenin; Humans; Inflammation; Interleukin-6; Mice; Osteogenesis; Vascular Calcification

2023