Compounds > 3,5-diiodothyropropionic acid
Page last updated: 2024-09-04

3,5-diiodothyropropionic acid and thyroxine

3,5-diiodothyropropionic acid has been researched along with thyroxine in 10 studies

Compound Research Comparison

Studies
(3,5-diiodothyropropionic acid)		Trials
(3,5-diiodothyropropionic acid)		Recent Studies (post-2010)
(3,5-diiodothyropropionic acid)		Studies
(thyroxine)		Trials
(thyroxine)		Recent Studies (post-2010) (thyroxine)
4741238,9891,4106,550

Protein Interaction Comparison

ProteinTaxonomy3,5-diiodothyropropionic acid (IC50)thyroxine (IC50)
TransthyretinHomo sapiens (human)2.1939
UDP-glucuronosyltransferase 1A1 Homo sapiens (human)5.25
Solute carrier organic anion transporter family member 4C1Homo sapiens (human)8
Bile acid receptorHomo sapiens (human)7.86

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (40.00)29.6817
2010's6 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Actis, M; Evison, B; Fujii, N; Inoue, A; Perry, S; Punchihewa, C1
Davis, FB; Davis, PJ; Mousa, SA; O'Connor, L1
Gerdes, AM; Hora, M; Liu, Y; Morkin, E; Redetzke, RA; Schlenker, EH1
Gerdes, AM; Liu, Y; Redetzke, RA; Sherer, BA; Wang, D1
Di Cosmo, C; Dumitrescu, AM; Liao, XH; Refetoff, S; Weiss, RE1
Davis, FB; Davis, PJ; Mousa, SA; Mousa, SS1
Anand, I; Barnhill, JG; Churby, L; Dunlap, M; Edson, RG; Erikson, J; Goldman, S; Hattler, B; Ladenson, PW; McCarren, M; Morkin, E; O'Brien, T; Shih, MC; Thai, H; Warner, A; Warren, SR1
Gerdes, AM; Iervasi, G1
Bonagura, JD; Chen, CA; Kalyanasundaram, A; Mahamud, SD; Nishijima, Y; Periasamy, M; Talukder, MA; Xie, L; Yang, F; Zweier, JL1
Bernal, J; Dumitrescu, AM; Ferrara, AM; Gil-Ibáñez, P; Liao, XH; Refetoff, S; Weiss, RE1

Reviews

1 review(s) available for 3,5-diiodothyropropionic acid and thyroxine

ArticleYear
Thyroid replacement therapy and heart failure.
    Circulation, 2010, Jul-27, Volume: 122, Issue:4

    Topics: Animals; Cardiovascular Diseases; Diiodothyronines; Disease Models, Animal; Glomerular Filtration Rate; Heart Failure; Homeostasis; Humans; Hyperthyroidism; Hypothyroidism; Kidney Tubules; Muscle Cells; Myocardial Contraction; Myocardial Infarction; Natriuretic Peptides; Propionates; Thyroid Hormones; Thyroxine; Triiodothyronine; Vasodilation

2010

Trials

1 trial(s) available for 3,5-diiodothyropropionic acid and thyroxine

ArticleYear
Effects of the thyromimetic agent diiodothyropropionic acid on body weight, body mass index, and serum lipoproteins: a pilot prospective, randomized, controlled study.
    The Journal of clinical endocrinology and metabolism, 2010, Volume: 95, Issue:3

    Topics: Aged; Body Mass Index; Body Weight; Chronic Disease; Diiodothyronines; Dose-Response Relationship, Drug; Double-Blind Method; Heart Failure; Humans; Lipoproteins; Middle Aged; Osteogenesis; Patient Selection; Pilot Projects; Propionates; Prospective Studies; Thyrotropin; Thyroxine; Time Factors; Treatment Outcome; Triiodothyronine

2010

Other Studies

8 other study(ies) available for 3,5-diiodothyropropionic acid and thyroxine

ArticleYear
Small molecule inhibitors of PCNA/PIP-box interaction suppress translesion DNA synthesis.
    Bioorganic & medicinal chemistry, 2013, Apr-01, Volume: 21, Issue:7

    Topics: Amino Acid Sequence; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cisplatin; DNA; DNA Damage; DNA Replication; HeLa Cells; Humans; Neoplasms; Proliferating Cell Nuclear Antigen; Protein Interaction Maps; Small Molecule Libraries; Structure-Activity Relationship

2013
Proangiogenesis action of the thyroid hormone analog 3,5-diiodothyropropionic acid (DITPA) is initiated at the cell surface and is integrin mediated.
    Endocrinology, 2006, Volume: 147, Issue:4

    Topics: Animals; Cell Membrane; Chick Embryo; Diiodothyronines; Fibroblast Growth Factor 2; Humans; Integrin alphaVbeta3; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neovascularization, Physiologic; Propionates; Thyroxine

2006
Effects of thyroidectomy, T4, and DITPA replacement on brain blood vessel density in adult rats.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2008, Volume: 294, Issue:5

    Topics: Animals; Blood Vessels; Body Temperature; Body Weight; Cerebrovascular Circulation; Diiodothyronines; Echocardiography; Heart Function Tests; Immunohistochemistry; Male; Platelet Endothelial Cell Adhesion Molecule-1; Propionates; Rats; Rats, Sprague-Dawley; Thyroidectomy; Thyroxine; Triiodothyronine

2008
Thyroid hormone analog 3,5-diiodothyropropionic acid promotes healthy vasculature in the adult myocardium independent of thyroid effects on cardiac function.
    American journal of physiology. Heart and circulatory physiology, 2009, Volume: 296, Issue:5

    Topics: Angiogenesis Inducing Agents; Animals; Body Temperature; Coronary Vessels; Diiodothyronines; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Implants; Heart Diseases; Hemodynamics; Hypothyroidism; Male; Neovascularization, Physiologic; Propionates; Rats; Rats, Sprague-Dawley; Thyroidectomy; Thyroxine; Triiodothyronine; Ultrasonography; Ventricular Function, Left

2009
A thyroid hormone analog with reduced dependence on the monocarboxylate transporter 8 for tissue transport.
    Endocrinology, 2009, Volume: 150, Issue:9

    Topics: Animals; Brain; Diiodothyronines; Iodide Peroxidase; Iodothyronine Deiodinase Type II; Liver; Male; Membrane Transport Proteins; Mice; Mice, Knockout; Monocarboxylic Acid Transporters; Propionates; Receptors, Thyroid Hormone; Symporters; Thyrotropin; Thyroxine

2009
Human platelet aggregation and degranulation is induced in vitro by L-thyroxine, but not by 3,5,3'-triiodo-L-thyronine or diiodothyropropionic acid (DITPA).
    Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 2010, Volume: 16, Issue:3

    Topics: Acetates; Adenosine Triphosphate; Adolescent; Blood Platelets; Collagen; Cytoplasmic Granules; Diiodothyronines; Female; Humans; Imidazoles; Male; Phenols; Platelet Activation; Platelet Aggregation; Propionates; Receptors, Thyroid Hormone; Substrate Specificity; Thyroxine; Triiodothyronine; Young Adult

2010
Detrimental effects of thyroid hormone analog DITPA in the mouse heart: increased mortality with in vivo acute myocardial ischemia-reperfusion.
    American journal of physiology. Heart and circulatory physiology, 2011, Volume: 300, Issue:2

    Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Blotting, Western; Cardiotonic Agents; Data Interpretation, Statistical; Diiodothyronines; Dose-Response Relationship, Drug; Echocardiography; Electrocardiography; Heart; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Myocardial Infarction; Myocardial Reperfusion Injury; Propionates; Sympathomimetics; Thyroxine; Triiodothyronine; Ventricular Function, Left

2011
Placenta passage of the thyroid hormone analog DITPA to male wild-type and Mct8-deficient mice.
    Endocrinology, 2014, Volume: 155, Issue:10

    Topics: Animals; Animals, Newborn; Biological Transport; Diiodothyronines; Embryo, Mammalian; Female; Male; Maternal-Fetal Exchange; Membrane Transport Proteins; Mice; Mice, Knockout; Monocarboxylic Acid Transporters; Placenta; Pregnancy; Propionates; Symporters; Thyroid Hormones; Thyroxine; Tissue Distribution

2014