3,5-diiodothyronine has been researched along with triiodothyronine in 55 studies
| Studies (3,5-diiodothyronine) | Trials (3,5-diiodothyronine) | Recent Studies (post-2010) (3,5-diiodothyronine) | Studies (triiodothyronine) | Trials (triiodothyronine) | Recent Studies (post-2010) (triiodothyronine) |
|---|---|---|---|---|---|
| 126 | 1 | 58 | 26,247 | 861 | 3,473 |
| Protein | Taxonomy | 3,5-diiodothyronine (IC50) | triiodothyronine (IC50) |
|---|---|---|---|
| Thyroid hormone receptor alpha | Homo sapiens (human) | 0.0006 | |
| Thyroid hormone receptor beta | Homo sapiens (human) | 0.0006 | |
| Proliferating cell nuclear antigen | Homo sapiens (human) | 3.6 | |
| Thyroid hormone receptor beta | Rattus norvegicus (Norway rat) | 0.0031 | |
| Adenosine receptor A1 | Homo sapiens (human) | 0.4109 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (18.18) | 18.7374 |
| 1990's | 10 (18.18) | 18.2507 |
| 2000's | 8 (14.55) | 29.6817 |
| 2010's | 25 (45.45) | 24.3611 |
| 2020's | 2 (3.64) | 2.80 |
| Authors | Studies |
|---|---|
| Bolger, MB; Dietrich, SW; Jorgensen, EC; Kollman, PA | 1 |
| Kvetny, J | 1 |
| Földes, O; Gschendtová, K; Langer, P | 1 |
| Ong, RL; Pittman, CS | 1 |
| Burger, AG; Engler, D | 1 |
| Faber, J; Friis, T; Heaf, J; Kirkegaard, C; Kølendorf, K; Lumholtz, IB; Siersbaek-Nielsen, K | 1 |
| Imura, H; Inada, M; Ishii, H; Mashio, Y; Naito, K; Nishikawa, M; Tanaka, K | 1 |
| Burger, AG; Engler, D; Merkelbach, U; Steiger, G | 1 |
| Chopra, IJ; Huang, TS; Hurd, RE; Solomon, DH | 2 |
| Brozmanová, H; Földes, O; Gschwendtová, K; Langer, P; Straussová, K | 1 |
| Barth, J; Goglia, F; Kadenbach, B; Lanni, A | 1 |
| Goglia, F; Lanni, A; Lombardi, A; Moreno, M | 2 |
| Davis, FB; Davis, PJ; Lin, HY; Thacore, HR | 1 |
| Craik, DJ; Duggan, BM | 1 |
| Brzezińska-Slebodzińska, E; Krysin, E | 1 |
| Baumgartner, A; Brödel, O; Eravci, M; Finke, R; Gräf, KJ; Hiedra, L; Hoell, T; Meinhold, H; Pinna, G; Prengel, H; Stoltenburg-Didinger, G; Thoma, R | 1 |
| Davis, FB; Davis, PJ; Gordinier, JK; Lin, HY; Martino, LJ; Wilcox, BD | 1 |
| Oommen, OV; Varghese, S | 1 |
| Beneduce, L; Colantuoni, V; Diano, S; Goglia, F; Lanni, A; Lombardi, A; Moreno, M; Ursini, MV | 1 |
| Oommen, OV; Shameena, B; Sudhakaran, PR; Varghese, S | 1 |
| Beneduce, L; Goglia, F; Lanni, A; Lombardi, A; Moreno, M; Pinna, G; Silvestri, E | 1 |
| Folkers, G; Hagenbuch, B; Klenk, U; Meier, PJ; Pizzagalli, F; Stieger, B | 1 |
| García-G, C; Jeziorski, MC; Orozco, A; Valverde-R, C | 1 |
| Demori, I; Fugassa, E; Gerdoni, E; Voci, A | 1 |
| Kabadi, UM | 1 |
| Alvarez, RM; Marti, MA; Petruk, AA | 1 |
| Canesi, L; Cioffi, F; De Matteis, R; Fugassa, E; Gallo, G; Goglia, F; Grasselli, E; Vergani, L; Voci, A | 1 |
| Hrabia, A; Pawlowska, K; Sechman, A | 1 |
| Canzoniero, LM; Del Viscovo, A; Esposito, A; Goglia, F; Moreno, M; Secondo, A | 1 |
| Ehrenkranz, JR; Goldberg, IJ; Huang, LS; Huggins, LA; Nagareddy, PR; Scanlan, TS; Yu, S | 1 |
| Busiello, RA; de Lange, P; De Matteis, R; Goglia, F; Lanni, A; Lombardi, A; Moreno, M; Napolitano, L; Senese, R | 1 |
| Kannan, K; Kunisue, T; Little, AG; Seebacher, F | 1 |
| Hernández-Puga, G; Holzer, G; Laudet, V; Mendoza, A; Navarrete-Ramírez, P; Orozco, A; Renaud, JP; Villalobos, P | 1 |
| Damiano, F; Gnoni, GV; Marsigliante, S; Rochira, A; Siculella, L | 1 |
| Luna, M; Navarrete-Ramírez, P; Orozco, A; Valverde-R, C | 1 |
| Little, AG; Seebacher, F | 1 |
| Bachurin, S; Chernopiatko, A; Costa-Nunes, J; Kubatiev, A; Malin, D; Markova, N; Schroeter, CA; Steinbusch, HM; Strekalova, T | 1 |
| Cioffi, F; de Lange, P; Goglia, F; Lanni, A; Senese, R | 1 |
| Araujo, RL; da Silva Leandro, M; de Andrade, BM; de Carvalho, DP; de Castro, JP; de Souza dos Santos, MC; Ferreira, AC; Neto, RA; Padron, AS; Pantaleão, TU | 1 |
| Brabant, G; Dörr, M; Friedrich, N; Homuth, G; Ittermann, T; Köhrle, J; Laqua, R; Lehmphul, I; Nauck, M; Pietzner, M; Schurmann, C; Völker, U; Völzke, H; Wallaschofski, H | 1 |
| Burke, J; Coughlin, L; Mdzinarishvili, A; Sadana, P; Woods, R | 1 |
| Cioffi, F; Coppola, M; Goglia, F; Moreno, M; Silvestri, E | 1 |
| Benod, C; da Silva Teixeira, S; Filgueira, C; Minze, LJ; Nunes, MT; Sieglaff, DH; Villagomez, R; Webb, P; Zhang, A | 1 |
| Hernández-Puga, G; Lazcano, I; Olvera, A; Orozco, A | 1 |
| Damiano, F; Gnoni, A; Rochira, A; Siculella, L | 1 |
| Buisine, N; Jiménez-Jacinto, V; Martyniuk, CJ; Olvera, A; Orozco, A; Sachs, LM; Sanchez-Flores, A | 1 |
| De Angelis, M; Feldt-Rasmussen, U; Giesert, F; Kiviranta, H; Li, ZM; Main, KM; Schramm, KW; Shen, H; Skakkebæk, NE; Toppari, J; Vogt-Weisenhorn, D | 1 |
| Cioffi, F; Coppola, M; de Lange, P; Gentile, A; Goglia, F; Lanni, A; Lombardi, A; Moreno, M; Senese, R; Silvestri, E | 1 |
| Hernández-Linares, Y; Lozano-Flores, C; Luna, M; Olvera, A; Orozco, A; Varela-Echavarría, A; Villalobos, P | 1 |
| Hernández-Puga, G; Lazcano, I; Orozco, A; Robles, JP | 1 |
| Rutigliano, G; Saponaro, F; Zucchi, R | 1 |
| Zucchi, R | 1 |
| Fröhlich, E; Wahl, R | 1 |
10 review(s) available for 3,5-diiodothyronine and triiodothyronine
| Article | Year |
|---|---|
Thyroxine analogues. 23. Quantitative structure-activity correlation studies of in vivo and in vitro thyromimetic activities.
Topics: Animals; Cell Nucleus; Goiter; In Vitro Techniques; Liver; Mathematics; Molecular Conformation; Protein Binding; Rats; Receptors, Cell Surface; Structure-Activity Relationship; Thyroxine; Thyroxine-Binding Proteins | 1977 |
The deiodination of the iodothyronines and of their derivatives in man.
Topics: Chemical Phenomena; Chemistry; Diiodothyronines; Diiodotyrosine; Glucuronates; Humans; Hyperthyroidism; Iodine; Kinetics; Phenyl Ethers; Radioimmunoassay; Sulfates; Thyronines; Thyroxine; Triiodothyronine; Triiodothyronine, Reverse | 1984 |
Thyroid: biological actions of 'nonclassical' thyroid hormones.
Topics: Animals; Diiodothyronines; Humans; Signal Transduction; Thyroid Gland; Thyroid Hormones; Thyronines; Thyroxine; Triiodothyronine; Triiodothyronine, Reverse | 2014 |
3,5-diiodo-L-thyronine: A Possible Pharmacological Agent?
Topics: Animals; Anti-Obesity Agents; Diiodothyronines; Humans; Hypolipidemic Agents; Hypothalamo-Hypophyseal System; Thyroid Gland; Triiodothyronine | 2016 |
Non-mammalian models reveal the role of alternative ligands for thyroid hormone receptors.
Topics: Animals; Biological Evolution; Diiodothyronines; Fishes; Gene Expression Regulation; Invertebrates; Iodide Peroxidase; Ligands; Phylogeny; Receptors, Thyroid Hormone; Signal Transduction; Species Specificity; Thyroid Epithelial Cells; Thyroxine; Triiodothyronine | 2017 |
Action of Thyroid Hormones, T3 and T2, on Hepatic Fatty Acids: Differences in Metabolic Effects and Molecular Mechanisms.
Topics: Animals; Diiodothyronines; Fatty Acids; Humans; Lipid Metabolism; Liver; Mitochondria; Models, Biological; Thyroxine; Triiodothyronine | 2017 |
Alternative ligands for thyroid hormone receptors.
Topics: Animals; Biological Mimicry; Diiodothyronines; Drug Design; Gene Expression Regulation; Humans; Ligands; Organ Specificity; Receptors, Thyroid Hormone; Signal Transduction; Thyronines; Triiodothyronine | 2019 |
Novel thyroid hormones.
Topics: Animals; Diiodothyronines; Humans; Thyronines; Thyroxine; Triiodothyronine | 2019 |
Thyroid Hormone Analogues: An Update.
Topics: Acetates; Anilides; Animals; Central Nervous System Diseases; Clinical Trials as Topic; Diiodothyronines; Drug Design; Dyslipidemias; Humans; Liver Diseases; Male; Mice; Mutation; Non-alcoholic Fatty Liver Disease; Phenols; Pyridazines; Rats; Signal Transduction; Thyroid Hormone Receptors alpha; Thyroid Hormone Receptors beta; Thyroid Hormones; Thyronines; Triiodothyronine; Uracil | 2020 |
Physiological Role and Use of Thyroid Hormone Metabolites - Potential Utility in COVID-19 Patients.
Topics: Comorbidity; COVID-19; Diiodothyronines; Humans; Iodide Peroxidase; SARS-CoV-2; Thyroid Diseases; Thyroid Hormones; Thyroxine; Triiodothyronine; Triiodothyronine, Reverse | 2021 |
45 other study(ies) available for 3,5-diiodothyronine and triiodothyronine
| Article | Year |
|---|---|
3,5-T2 stimulates oxygen consumption, but not glucose uptake in human mononuclear blood cells.
Topics: Adult; Blood Glucose; Diiodothyronines; DNA; Humans; In Vitro Techniques; Middle Aged; Neutrophils; Oxygen Consumption; Thyroxine; Triiodothyronine | 1992 |
Effect of ethanol and linoleic acid on changes in biliary excretion of iodothyronines possibly related to thyroxine deiodination in rat liver.
Topics: Animals; Bile; Diiodothyronines; Ethanol; Linoleic Acids; Liver; Male; Rats; Rats, Inbred Strains; Thyroxine; Triiodothyronine | 1988 |
Proton nuclear magnetic resonance assignments of thyroid hormone and its analogues.
Topics: Diiodothyronines; Magnetic Resonance Spectroscopy; Thyroid Hormones; Thyronines; Thyroxine; Triiodothyronine; Triiodothyronine, Reverse | 1985 |
Simultaneous turnover studies of thyroxine, 3,5,3' and 3,3',5'-triiodothyronine, 3,5-, 3,3'-, and 3',5'- diiodothyronine, and 3'-monoiodothyronine in chronic renal failure.
Topics: Adult; Aged; Diiodothyronines; Female; Humans; Iodine Radioisotopes; Kidney Failure, Chronic; Kinetics; Male; Middle Aged; Serum Albumin; Thyroid Hormones; Thyronines; Thyrotropin; Thyrotropin-Releasing Hormone; Thyroxine; Triiodothyronine; Triiodothyronine, Reverse | 1983 |
Serum concentrations of 3, 3'-diiodothyronine, 3', 5'-diiodothyronine, and 3, 5-diiodothyronine in altered thyroid states.
Topics: Adult; Diiodothyronines; Humans; Hyperthyroidism; Hypothyroidism; Middle Aged; Thyronines; Thyroxine; Triiodothyronine | 1983 |
The monodeiodination of triiodothyronine and reverse triiodothyronine in man: a quantitative evaluation of the pathway by the use of turnover rate techniques.
Topics: Chemical Precipitation; Chromatography, Ion Exchange; Chromatography, Paper; Diiodothyronines; Humans; Hypothyroidism; Immunochemistry; Iodine; Metabolic Clearance Rate; Radioimmunoassay; Triiodothyronine; Triiodothyronine, Reverse | 1984 |
Effect of 3,5,3'-triiodothyronine-induced hyperthyroidism on iodothyronine metabolism in the rat: evidence for tissue differences in metabolic responses.
Topics: Animals; Diiodothyronines; Hyperthyroidism; Kinetics; Male; Rats; Rats, Inbred Strains; Thyronines; Thyroxine; Triiodothyronine | 1984 |
Thyromimetic effects of 3,5-dimethyl,3'-isopropyl thyronine (DIMIT) and 3,5-diethyl,3'-isopropyl thyronine (DIET) in various tissues of the rat.
Topics: Animals; Biotransformation; Cerebral Cortex; Diiodothyronines; Liver; Male; Myocardium; Rats; Thyroid Hormones; Thyronines; Thyrotropin; Thyroxine; Triiodothyronine | 1984 |
In vivo study of iodothyronine deiodination in rat liver: effect of salicylate on biliary excretion of several iodothyronines.
Topics: Animals; Bile; Biliary Tract; Diiodothyronines; Iodide Peroxidase; Liver; Male; Rats; Rats, Inbred Strains; Salicylates; Thyroid Hormones; Thyroxine; Triiodothyronine | 1983 |
Interaction of diiodothyronines with isolated cytochrome c oxidase.
Topics: Animals; Cattle; Diiodothyronines; Electron Transport Complex IV; Hydrogen-Ion Concentration; Mitochondria, Heart; Oxygen Consumption; Protein Conformation; Spectrophotometry; Triiodothyronine | 1994 |
Rapid stimulation in vitro of rat liver cytochrome oxidase activity by 3,5-diiodo-L-thyronine and by 3,3'-diiodo-L-thyronine.
Topics: Animals; Body Weight; Diiodothyronines; Electron Transport Complex IV; Energy Metabolism; Enzyme Activation; Hypothyroidism; Iodide Peroxidase; Liver; Male; Mitochondria, Liver; Organ Size; Rats; Rats, Wistar; Triiodothyronine | 1994 |
Thyroid hormone analogues potentiate the antiviral action of interferon-gamma by two mechanisms.
Topics: Antiviral Agents; Cycloheximide; Diiodothyronines; Drug Synergism; HeLa Cells; Humans; Interferon-gamma; Protein Biosynthesis; Sensitivity and Specificity; Thyroid Hormones; Thyroxine; Triiodothyronine | 1996 |
1H and 13C NMR relaxation studies of molecular dynamics of the thyroid hormones thyroxine, 3,5,3'-triiodothyronine, and 3,5-diiodothyronine.
Topics: Alanine; Chemical Phenomena; Chemistry, Physical; Diiodothyronines; Fourier Analysis; Magnetic Resonance Spectroscopy; Mathematics; Molecular Conformation; Molecular Structure; Protons; Thyroxine; Triiodothyronine | 1996 |
Ontogeny of the generation of diiodothyronines (3,3'-T2 and 3',5'-T2) from triiodothyronines in the liver and kidney during the fetal life of the pig.
Topics: Animals; Diiodothyronines; Embryonic and Fetal Development; Female; Gestational Age; Kidney; Liver; Pregnancy; Swine; Triiodothyronine; Triiodothyronine, Reverse | 1996 |
Elevated 3,5-diiodothyronine concentrations in the sera of patients with nonthyroidal illnesses and brain tumors.
Topics: Astrocytoma; Brain Injuries; Brain Neoplasms; Craniocerebral Trauma; Diiodothyronines; Glioblastoma; Humans; Liver Diseases; Radioimmunoassay; Reference Values; Sensitivity and Specificity; Sepsis; Thyroxine; Triiodothyronine | 1997 |
3,5-Diiodo-L-thyronine and 3,5,3'-triiodo-L-thyronine both improve the cold tolerance of hypothyroid rats, but possibly via different mechanisms.
Topics: Adaptation, Physiological; Adipose Tissue, Brown; Animals; Body Weight; Cold Temperature; Diiodothyronines; Energy Metabolism; Hypothyroidism; Liver; Male; Muscle, Skeletal; Myocardium; Organ Size; Oxygen Consumption; Rats; Rats, Wistar; Triiodothyronine | 1998 |
Potentiation by thyroid hormone of human IFN-gamma-induced HLA-DR expression.
Topics: Biological Transport; Cell Nucleus; Dextrothyroxine; Diiodothyronines; Drug Synergism; Genistein; HeLa Cells; HLA-DR Antigens; Humans; Interferon-gamma; Interferon-Stimulated Gene Factor 3; Nuclear Proteins; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; RNA, Messenger; Thyroxine; Time Factors; Trans-Activators; Transcription Factors; Triiodothyronine; Triiodothyronine, Reverse; Tyrosine | 1998 |
Thyroid hormones regulate lipid metabolism in a teleost Anabas testudineus (Bloch).
Topics: Animals; Antithyroid Agents; Cholesterol; Diiodothyronines; Fatty Acids; Female; Glucosephosphate Dehydrogenase; Isocitrate Dehydrogenase; Lipid Metabolism; Lipids; Lipoproteins; Liver; Muscles; Perches; Phospholipids; Propylthiouracil; Triglycerides; Triiodothyronine | 1999 |
3,5-diiodo-L-thyronine regulates glucose-6-phosphate dehydrogenase activity in the rat.
Topics: Animals; Diiodothyronines; Glucosephosphate Dehydrogenase; Glycerolphosphate Dehydrogenase; Humans; Malate Dehydrogenase; Male; Rats; Rats, Wistar; Triiodothyronine | 2000 |
Short-term effects of thyroid hormones on lipogenic enzymes and 14C-acetate incorporation into various lipid classes: in vivo and in vitro studies.
Topics: Acetic Acid; Animals; Cholesterol; Diiodothyronines; Female; Glucosephosphate Dehydrogenase; In Vitro Techniques; Isocitrate Dehydrogenase; Lipid Metabolism; Malate Dehydrogenase; Malate Dehydrogenase (NADP+); Perciformes; Phosphogluconate Dehydrogenase; Thyroid Hormones; Triiodothyronine | 2001 |
Are the effects of T3 on resting metabolic rate in euthyroid rats entirely caused by T3 itself?
Topics: Animals; Antithyroid Agents; Basal Metabolism; Dactinomycin; Diiodothyronines; Enzyme Inhibitors; Hypothyroidism; Iodide Peroxidase; Iopanoic Acid; Liver; Male; Propylthiouracil; Protein Synthesis Inhibitors; Radioimmunoassay; Rats; Rats, Wistar; Thyroid Gland; Triiodothyronine | 2002 |
Identification of a novel human organic anion transporting polypeptide as a high affinity thyroxine transporter.
Topics: Amino Acid Sequence; Animals; Brain; CHO Cells; Chromosomes, Human, Pair 12; Cloning, Molecular; Cricetinae; Diiodothyronines; Estradiol; Estrone; Female; Humans; Leydig Cells; Male; Membrane Proteins; Molecular Sequence Data; Oocytes; Organ Specificity; Organic Anion Transporters; Sequence Homology, Amino Acid; Sulfobromophthalein; Testis; Thyroxine; Triiodothyronine; Xenopus | 2002 |
Effects of iodothyronines on the hepatic outer-ring deiodinating pathway in killifish.
Topics: Animals; Diiodothyronines; Enzyme Activation; Fundulidae; Gene Expression Regulation, Enzymologic; Iodide Peroxidase; Iodothyronine Deiodinase Type II; Liver; Male; Polymerase Chain Reaction; RNA, Messenger; Thyroid Gland; Thyroxine; Triiodothyronine | 2004 |
3,5-diiodothyronine mimics the effect of triiodothyronine on insulin-like growth factor binding protein-4 expression in cultured rat hepatocytes.
Topics: Animals; Cells, Cultured; Diiodothyronines; Dose-Response Relationship, Drug; Gene Expression Regulation; Hepatocytes; Insulin-Like Growth Factor Binding Protein 4; Male; Rats; Rats, Wistar; RNA, Messenger; Triiodothyronine | 2004 |
Role of thyrotropin in metabolism of thyroid hormones in nonthyroidal tissues.
Topics: Animals; Diiodothyronines; Dogs; Female; Kinetics; Thyroid Hormones; Thyrotropin; Thyroxine; Triiodothyronine | 2006 |
Thyroid hormone interactions with DMPC bilayers. A molecular dynamics study.
Topics: Computer Simulation; Diiodothyronines; Dimyristoylphosphatidylcholine; Lipid Bilayers; Lipids; Models, Molecular; Molecular Structure; Static Electricity; Thyroxine; Triiodothyronine; Water | 2009 |
Direct effects of iodothyronines on excess fat storage in rat hepatocytes.
Topics: Acyl-CoA Oxidase; Animals; Catalase; Cells, Cultured; Diiodothyronines; Fatty Liver; Gene Expression; Hepatocytes; Lipid Metabolism; Non-alcoholic Fatty Liver Disease; Oleic Acid; Palmitates; PPAR alpha; PPAR delta; PPAR gamma; Rats; RNA, Messenger; Superoxide Dismutase; Triiodothyronine | 2011 |
Effect of 3,3',5-triiodothyronine and 3,5-diiodothyronine on progesterone production, cAMP synthesis, and mRNA expression of STAR, CYP11A1, and HSD3B genes in granulosa layer of chicken preovulatory follicles.
Topics: Animals; Chickens; Cholesterol Side-Chain Cleavage Enzyme; Cyclic AMP; Diiodothyronines; Female; Ovarian Follicle; Phosphoproteins; Progesterone; Progesterone Reductase; RNA, Messenger; Triiodothyronine | 2011 |
Intracellular and plasma membrane-initiated pathways involved in the [Ca2+]i elevations induced by iodothyronines (T3 and T2) in pituitary GH3 cells.
Topics: Calcium; Calcium Signaling; Carrier Proteins; Cell Membrane; Cells, Cultured; Diiodothyronines; Fluorescein; Fluorescent Dyes; Homeostasis; Humans; Inositol 1,4,5-Trisphosphate; Intracellular Membranes; Ion Channels; Mitochondria; Nitric Oxide; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Pituitary Gland; Signal Transduction; Sodium; Transfection; Triiodothyronine | 2012 |
Thyroid hormone reduces cholesterol via a non-LDL receptor-mediated pathway.
Topics: Animals; Apolipoproteins B; Cholesterol; Diiodothyronines; Liver; Mice; Mice, Knockout; Receptors, LDL; Scavenger Receptors, Class B; Thyroxine; Triiodothyronine | 2012 |
Responses of skeletal muscle lipid metabolism in rat gastrocnemius to hypothyroidism and iodothyronine administration: a putative role for FAT/CD36.
Topics: Animals; Blotting, Western; Calorimetry, Indirect; CD36 Antigens; Cell Line; Diiodothyronines; Fatty Acids, Nonesterified; Hypothyroidism; Immunohistochemistry; Lipid Metabolism; Male; Mice; Mitochondria, Muscle; Muscle, Skeletal; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; RNA, Messenger; Triiodothyronine | 2012 |
Thyroid hormone actions are temperature-specific and regulate thermal acclimation in zebrafish (Danio rerio).
Topics: Acclimatization; Animals; Body Temperature Regulation; Dietary Supplements; Diiodothyronines; Hypothyroidism; Multivariate Analysis; Muscles; Organ Specificity; RNA, Messenger; Temperature; Thyroid Hormones; Triiodothyronine; Zebrafish | 2013 |
3,5-T2 is an alternative ligand for the thyroid hormone receptor β1.
Topics: Animals; Binding Sites; Binding, Competitive; Cell Line; Cell Line, Tumor; Diiodothyronines; Dose-Response Relationship, Drug; Fish Proteins; Gene Expression; HEK293 Cells; Humans; Kinetics; Ligands; Protein Isoforms; Recombinant Fusion Proteins; Reverse Transcriptase Polymerase Chain Reaction; Thyroid Hormone Receptors beta; Tilapia; Transcriptional Activation; Transfection; Triiodothyronine | 2013 |
3,5-Diiodo-l-thyronine induces SREBP-1 proteolytic cleavage block and apoptosis in human hepatoma (Hepg2) cells.
Topics: Apoptosis; Diiodothyronines; Fatty Acid Synthase, Type I; Gene Expression Regulation; Hep G2 Cells; Humans; Mitogen-Activated Protein Kinase Kinases; p38 Mitogen-Activated Protein Kinases; Protein Kinase C-delta; Proteolysis; Proto-Oncogene Proteins c-akt; Signal Transduction; Sterol Regulatory Element Binding Protein 1; Triiodothyronine | 2013 |
3,5-di-iodothyronine stimulates tilapia growth through an alternate isoform of thyroid hormone receptor β1.
Topics: Animals; Body Weight; Diiodothyronines; Gene Expression Regulation; Insulin-Like Growth Factor I; Iodide Peroxidase; Iodothyronine Deiodinase Type II; Liver; Protein Isoforms; Thyroid Hormone Receptors beta; Tilapia; Triiodothyronine | 2014 |
Thyroid hormone regulates cardiac performance during cold acclimation in zebrafish (Danio rerio).
Topics: Acclimatization; Animals; Autonomic Nervous System; Cardiac Output; Cold Temperature; Diiodothyronines; Female; Heart; Heart Rate; Male; Real-Time Polymerase Chain Reaction; RNA, Messenger; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Stroke Volume; Triiodothyronine; Zebrafish | 2014 |
Hippocampal gene expression of deiodinases 2 and 3 and effects of 3,5-diiodo-L-thyronine T2 in mouse depression paradigms.
Topics: Animals; Depressive Disorder; Diiodothyronines; Gene Expression Regulation, Enzymologic; Hippocampus; Iodide Peroxidase; Iodothyronine Deiodinase Type II; Mice; Mitochondria; Signal Transduction; Triiodothyronine | 2013 |
Administration of 3,5-diiodothyronine (3,5-T2) causes central hypothyroidism and stimulates thyroid-sensitive tissues.
Topics: Animals; Basal Metabolism; Diiodothyronines; Dual Oxidases; Flavoproteins; Hypothalamo-Hypophyseal System; Hypothyroidism; Immunoblotting; Iodide Peroxidase; Iodides; Iodothyronine Deiodinase Type II; Kidney; Liver; Male; NADPH Oxidase 4; NADPH Oxidases; Oxygen Consumption; Rats; Rats, Wistar; Receptors, Thyrotropin; Reverse Transcriptase Polymerase Chain Reaction; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine | 2014 |
Translating pharmacological findings from hypothyroid rodents to euthyroid humans: is there a functional role of endogenous 3,5-T2?
Topics: Adult; Aged; Diiodothyronines; Female; Humans; Hypothyroidism; Leptin; Male; Middle Aged; Thyrotropin; Thyroxine; Triiodothyronine; Young Adult | 2015 |
Anti-edema action of thyroid hormone in MCAO model of ischemic brain stroke: Possible association with AQP4 modulation.
Topics: Animals; Aquaporin 4; Brain Edema; Cerebrovascular Circulation; Diiodothyronines; Infarction, Middle Cerebral Artery; Injections, Intravenous; Male; Mice; Stroke; Triiodothyronine | 2015 |
3,5-diiodothyronine (3,5-T2) reduces blood glucose independently of insulin sensitization in obese mice.
Topics: Animals; Blood Glucose; Diet, High-Fat; Diiodothyronines; Energy Metabolism; Hep G2 Cells; Humans; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Obesity; Triiodothyronine | 2017 |
Differential transcriptome regulation by 3,5-T2 and 3',3,5-T3 in brain and liver uncovers novel roles for thyroid hormones in tilapia.
Topics: Animals; Brain; Cluster Analysis; Diiodothyronines; Fish Proteins; Gene Expression Regulation; Liver; Organ Specificity; Signal Transduction; Tilapia; Transcriptome; Triiodothyronine | 2017 |
Determination of thyroid hormones in placenta using isotope-dilution liquid chromatography quadrupole time-of-flight mass spectrometry.
Topics: Animals; Chromatography, Liquid; Diiodothyronines; Female; Humans; Isotope Labeling; Isotopes; Limit of Detection; Liquid-Liquid Extraction; Mass Spectrometry; Mice; Placenta; Pregnancy; Reference Standards; Solid Phase Extraction; Thyroid Hormones; Thyroxine; Triiodothyronine | 2018 |
Differential Effects of 3,5-Diiodo-L-Thyronine and 3,5,3'-Triiodo-L-Thyronine On Mitochondrial Respiratory Pathways in Liver from Hypothyroid Rats.
Topics: Animals; Diiodothyronines; Electron Transport; Hypothyroidism; Male; Mitochondria, Liver; Rats; Rats, Wistar; Triiodothyronine | 2018 |
3,5-T2 and 3,3',5-T3 Regulate Cerebellar Thyroid Hormone Signalling and Myelin Molecular Dynamics in Tilapia.
Topics: Animals; Cell Culture Techniques; Cerebellum; Cichlids; Diiodothyronines; Gene Expression Regulation; Male; Models, Animal; Myelin Sheath; Signal Transduction; Thyroid Gland; Triiodothyronine | 2019 |