Page last updated: 2024-09-02

3,5-dihydroxyphenylglycine and sirolimus

3,5-dihydroxyphenylglycine has been researched along with sirolimus in 3 studies

Compound Research Comparison

Studies
(3,5-dihydroxyphenylglycine)
Trials
(3,5-dihydroxyphenylglycine)
Recent Studies (post-2010)
(3,5-dihydroxyphenylglycine)
Studies
(sirolimus)
Trials
(sirolimus)
Recent Studies (post-2010) (sirolimus)
30116120,7112,36811,516

Protein Interaction Comparison

ProteinTaxonomy3,5-dihydroxyphenylglycine (IC50)sirolimus (IC50)
Bile salt export pumpHomo sapiens (human)10
ATP-dependent translocase ABCB1Homo sapiens (human)1.25
Cytochrome P450 3A4Homo sapiens (human)2
Cytochrome P450 2C9 Homo sapiens (human)2
Peptidyl-prolyl cis-trans isomerase FKBP1AMus musculus (house mouse)0.001
Cytochrome P450 2C19Homo sapiens (human)4
Serine/threonine-protein kinase mTORHomo sapiens (human)0.0897
Peptidyl-prolyl cis-trans isomerase FKBP1AHomo sapiens (human)0.0042
Regulatory-associated protein of mTORHomo sapiens (human)0.225
Target of rapamycin complex subunit LST8Homo sapiens (human)0.225
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)1.9
Solute carrier organic anion transporter family member 1B1Homo sapiens (human)1.1

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hsu, KS; Huang, CC; You, JL; Zho, WM1
Hou, L; Klann, E1
Bennett, MV; Francesconi, A; Kumari, R; Takayasu, Y; Takeuchi, K; Zukin, RS1

Other Studies

3 other study(ies) available for 3,5-dihydroxyphenylglycine and sirolimus

ArticleYear
The group I metabotropic glutamate receptor agonist (S)-3,5-dihydroxyphenylglycine induces a novel form of depotentiation in the CA1 region of the hippocampus.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002, Oct-15, Volume: 22, Issue:20

    Topics: Animals; Anti-Bacterial Agents; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Glycine; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; Neural Inhibition; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, AMPA; Receptors, Metabotropic Glutamate; Resorcinols; Sirolimus; Synaptic Transmission

2002
Activation of the phosphoinositide 3-kinase-Akt-mammalian target of rapamycin signaling pathway is required for metabotropic glutamate receptor-dependent long-term depression.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004, Jul-14, Volume: 24, Issue:28

    Topics: 3-Phosphoinositide-Dependent Protein Kinases; Androstadienes; Animals; Benzoates; Chromones; Dendrites; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Glycine; Hippocampus; Long-Term Synaptic Depression; Male; Mice; Mice, Inbred C57BL; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinases; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyramidal Cells; Pyridines; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Signal Transduction; Sirolimus; Synaptosomes; Tacrolimus; TOR Serine-Threonine Kinases; Wortmannin

2004
Caveolin-1 knockout mice exhibit impaired induction of mGluR-dependent long-term depression at CA3-CA1 synapses.
    Proceedings of the National Academy of Sciences of the United States of America, 2010, Dec-14, Volume: 107, Issue:50

    Topics: Animals; Antibiotics, Antineoplastic; Butadienes; Caveolin 1; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Extracellular Signal-Regulated MAP Kinases; Glycine; Hippocampus; Long-Term Synaptic Depression; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitriles; Patch-Clamp Techniques; Receptors, Metabotropic Glutamate; Resorcinols; Signal Transduction; Sirolimus; Synapses; TOR Serine-Threonine Kinases

2010