3,5-dihydroxyphenylglycine has been researched along with quisqualic acid in 15 studies
| Studies (3,5-dihydroxyphenylglycine) | Trials (3,5-dihydroxyphenylglycine) | Recent Studies (post-2010) (3,5-dihydroxyphenylglycine) | Studies (quisqualic acid) | Trials (quisqualic acid) | Recent Studies (post-2010) (quisqualic acid) |
|---|---|---|---|---|---|
| 301 | 1 | 61 | 1,362 | 0 | 36 |
| 22 | 0 | 10 | 1,362 | 0 | 36 |
| Protein | Taxonomy | 3,5-dihydroxyphenylglycine (IC50) | quisqualic acid (IC50) |
|---|---|---|---|
| Chain A, Glutamate Receptor 2 | Rattus norvegicus (Norway rat) | 0.02 | |
| Chain A, Glutamate Receptor 2 | Rattus norvegicus (Norway rat) | 0.02 | |
| Glutamate receptor 1 | Rattus norvegicus (Norway rat) | 5.1 | |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | 5.1 | |
| Glutamate receptor 3 | Rattus norvegicus (Norway rat) | 5.1 | |
| Glutamate receptor 4 | Rattus norvegicus (Norway rat) | 5.1 | |
| Glutamate receptor ionotropic, kainate 1 | Rattus norvegicus (Norway rat) | 0.15 | |
| Glutamate receptor 1 | Mus musculus (house mouse) | 0.08 | |
| Glutamate receptor 2 | Mus musculus (house mouse) | 0.08 | |
| Glutamate receptor ionotropic, kainate 2 | Rattus norvegicus (Norway rat) | 0.15 | |
| Glutamate receptor ionotropic, kainate 3 | Rattus norvegicus (Norway rat) | 0.15 | |
| Glutamate receptor ionotropic, kainate 4 | Rattus norvegicus (Norway rat) | 0.15 | |
| Glutamate carboxypeptidase 2 | Homo sapiens (human) | 9.5 | |
| Glutamate receptor ionotropic, kainate 5 | Rattus norvegicus (Norway rat) | 0.15 | |
| Cystine/glutamate transporter | Homo sapiens (human) | 5 | |
| Glutamate receptor 4 | Mus musculus (house mouse) | 0.08 | |
| Glutamate receptor 3 | Mus musculus (house mouse) | 0.08 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (33.33) | 18.2507 |
| 2000's | 9 (60.00) | 29.6817 |
| 2010's | 1 (6.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Adam, G; Bleuel, Z; Chaboz, S; Ellis, GJ; Faull, RL; Malherbe, P; Messer, J; Metzler, V; Mutel, V; Nilly, A; Richards, JG; Roughley, BS; Schlaeger, EJ | 1 |
| Bischoff, F; Janssen, C; Langlois, X; Lavreysen, H; Lesage, AS; Leysen, JE | 1 |
| Belagaje, R; Burnett, JP; Johnson, BG; Mayne, NG; Monn, JA; Salhoff, CR; Schoepp, DD; Wright, RA; Wu, S | 1 |
| Chu, Z; Hablitz, JJ | 1 |
| Gao, C; Hu, HZ; Liu, S; Ren, J; Wood, JD; Xia, Y | 1 |
| Copani, A; Fisichella, G; Frati, C; Marchese, C; Nasca, MR; Nicoletti, F; Storto, M | 1 |
| Croucher, MJ; Harris, JR; Jane, DE; Thomas, LS | 1 |
| Battaglia, G; Bruno, V; Ceña, V; Cespédes, VM; Copani, A; Flor, PJ; Galindo, MF; Gasparini, F; Kuhn, R; Nicoletti, F; Sánchez-Prieto, J | 1 |
| Beltramo, M; Brusa, R; Lozza, G; Mancini, I; Petrò, R; Reggiani, A; Scandroglio, P | 1 |
| Acher, FC; Brabet, I; Jullian, N; Pin, JP | 1 |
| Costantino, G; Macchiarulo, A; Pellicciari, R | 1 |
| Bräuner-Osborne, H; Egebjerg, J; Krogsgaard-Larsen, P; Madsen, U; Nielsen, EO | 1 |
| Acher, FC; Bertrand, HO; Bessis, AS; Pin, JP | 1 |
| Acher, F; Bertrand, HO; Brabet, I; Pin, JP; Triballeau, N | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
1 review(s) available for 3,5-dihydroxyphenylglycine and quisqualic acid
| Article | Year |
|---|---|
Ligands for glutamate receptors: design and therapeutic prospects.
Topics: Animals; Drug Design; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Humans; Ligands; N-Methylaspartate; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Synapses | 2000 |
14 other study(ies) available for 3,5-dihydroxyphenylglycine and quisqualic acid
| Article | Year |
|---|---|
Characterization of [(3)H]Quisqualate binding to recombinant rat metabotropic glutamate 1a and 5a receptors and to rat and human brain sections.
Topics: Animals; Binding, Competitive; Brain; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Humans; Imidazoles; Indans; Intracellular Fluid; Kainic Acid; Male; Organ Specificity; Quinazolines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Recombinant Proteins; Spinal Cord; Transfection | 2000 |
[3H]R214127: a novel high-affinity radioligand for the mGlu1 receptor reveals a common binding site shared by multiple allosteric antagonists.
Topics: Adamantane; Allosteric Regulation; Animals; Binding Sites; Binding, Competitive; Brain; Cell Line; Cell Membrane; CHO Cells; Chromones; Cricetinae; Humans; Naphthalenes; Pyrans; Quinolines; Quinoxalines; Quisqualic Acid; Radioligand Assay; Rats; Receptors, Metabotropic Glutamate; Transfection; Tritium | 2003 |
The novel metabotropic glutamate receptor agonist 2R,4R-APDC potentiates stimulation of phosphoinositide hydrolysis in the rat hippocampus by 3,5-dihydroxyphenylglycine: evidence for a synergistic interaction between group 1 and group 2 receptors.
Topics: Aging; Animals; Animals, Newborn; Brain; Cloning, Molecular; Colforsin; Cyclic AMP; Cycloleucine; Drug Synergism; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Humans; Inositol; Kinetics; Neuroprotective Agents; Phosphatidylinositols; Proline; Quisqualic Acid; Rats; Receptors, Metabotropic Glutamate; Recombinant Proteins; Resorcinols; Second Messenger Systems | 1996 |
Activation of group I mGluRs increases spontaneous IPSC frequency in rat frontal cortex.
Topics: Amino Acids, Dicarboxylic; Aminobutyrates; Animals; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Frontal Lobe; Glycine; Neural Inhibition; Neuroprotective Agents; Patch-Clamp Techniques; Pyramidal Cells; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols; Synaptic Transmission; Tetrodotoxin | 1998 |
Functional group I metabotropic glutamate receptors in submucous plexus of guinea-pig ileum.
Topics: Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Guinea Pigs; Ileum; Male; Membrane Potentials; Quisqualic Acid; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Submucous Plexus | 1999 |
Expression of functional mGlu5 metabotropic glutamate receptors in human melanocytes.
Topics: Amino Acid Sequence; Animals; Cell Death; Cells, Cultured; Cerebral Cortex; DNA; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Glycine; Humans; Immunohistochemistry; Infant, Newborn; Male; Melanocytes; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Phosphatidylinositol Phosphates; Pigmentation Disorders; Quisqualic Acid; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Skin; Sodium Glutamate; Tissue Extracts | 2000 |
Metabotropic glutamate autoreceptors of the mGlu(5) subtype positively modulate neuronal glutamate release in the rat forebrain in vitro.
Topics: Animals; Aspartic Acid; Autoreceptors; Benzoates; Calcium; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; In Vitro Techniques; Indans; Male; Neurons; Phenylacetates; Prosencephalon; Quisqualic Acid; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Tetrodotoxin; Tritium | 2000 |
An activity-dependent switch from facilitation to inhibition in the control of excitotoxicity by group I metabotropic glutamate receptors.
Topics: Animals; Cells, Cultured; Cerebral Cortex; Enzyme Activation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Mice; N-Methylaspartate; Nerve Degeneration; Neural Inhibition; Neuroprotective Agents; Neurotoxins; Protein Kinase C; Quisqualic Acid; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Time Factors | 2001 |
Evaluation of cannabinoid receptor 2 and metabotropic glutamate receptor 1 functional responses using a cell impedance-based technology.
Topics: Analgesics; Animals; Benzimidazoles; Biological Assay; Calcium; Cannabinoids; CHO Cells; Chromones; Cricetinae; Cricetulus; Cyclic AMP; Cyclohexanols; Cycloleucine; Electric Impedance; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Indoles; Naphthalenes; Neuroprotective Agents; Quinolines; Quisqualic Acid; Receptor, Cannabinoid, CB2; Receptors, Metabotropic Glutamate; Resorcinols; Signal Transduction; Thiazoles | 2010 |
Agonist selectivity of mGluR1 and mGluR2 metabotropic receptors: a different environment but similar recognition of an extended glutamate conformation.
Topics: Animals; Binding Sites; Cell Line; CHO Cells; Cricetinae; Glutamates; Ligands; Models, Molecular; Molecular Conformation; Receptors, Metabotropic Glutamate; Structure-Activity Relationship | 1999 |
Pharmacophore models of group I and group II metabotropic glutamate receptor agonists. Analysis of conformational, steric, and topological parameters affecting potency and selectivity.
Topics: Excitatory Amino Acid Agonists; Ligands; Molecular Conformation; Receptors, Metabotropic Glutamate; Structure-Activity Relationship | 1999 |
Common and selective molecular determinants involved in metabotopic glutamate receptor agonist activity.
Topics: Binding Sites; Crystallography, X-Ray; Excitatory Amino Acid Agonists; Glutamic Acid; Ligands; Models, Molecular; Receptors, Metabotropic Glutamate; Sequence Homology, Amino Acid; Structure-Activity Relationship | 2002 |
Virtual screening workflow development guided by the "receiver operating characteristic" curve approach. Application to high-throughput docking on metabotropic glutamate receptor subtype 4.
Topics: Binding Sites; Databases, Factual; Drug Design; Models, Molecular; Quantitative Structure-Activity Relationship; Receptors, Metabotropic Glutamate; ROC Curve | 2005 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |