3,5-dihydroxyphenylglycine has been researched along with n-methylaspartate in 24 studies
| Studies (3,5-dihydroxyphenylglycine) | Trials (3,5-dihydroxyphenylglycine) | Recent Studies (post-2010) (3,5-dihydroxyphenylglycine) | Studies (n-methylaspartate) | Trials (n-methylaspartate) | Recent Studies (post-2010) (n-methylaspartate) |
|---|---|---|---|---|---|
| 301 | 1 | 61 | 10,408 | 59 | 1,902 |
| 22 | 0 | 10 | 10,408 | 59 | 1,902 |
| Protein | Taxonomy | 3,5-dihydroxyphenylglycine (IC50) | n-methylaspartate (IC50) |
|---|---|---|---|
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | 5.175 | |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | 5.175 | |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | 5.175 | |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | 5.175 | |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | 5.175 | |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | 5.175 | |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | 5.175 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (20.83) | 18.2507 |
| 2000's | 16 (66.67) | 29.6817 |
| 2010's | 2 (8.33) | 24.3611 |
| 2020's | 1 (4.17) | 2.80 |
| Authors | Studies |
|---|---|
| Bernardi, G; Calabresi, P; Centonze, D; Pisani, A | 1 |
| Bordi, F; Corsi, M; Ugolini, A | 1 |
| El Manira, A; Grillner, S; Krieger, P | 1 |
| Davidoff, RA; Hackman, JC; Holohean, AM | 1 |
| Hirate, K; Nishikawa, T; Ohnishi, Y; Sato, T; Tanaka, K; Teramoto, T | 1 |
| Mao, L; Wang, JQ | 1 |
| Barbanel, G; Cambonie, G; Kamenka, JM; Laplanche, L | 1 |
| Domenici, MR; Pèzzola, A; Pintor, A; Popoli, P; Potenza, RL; Reggio, R; Tiburzi, F | 1 |
| Collingridge, GL; Irving, AJ; Martin, DJ; Rae, MG | 1 |
| Battaglia, G; Bruno, V; Ceña, V; Cespédes, VM; Copani, A; Flor, PJ; Galindo, MF; Gasparini, F; Kuhn, R; Nicoletti, F; Sánchez-Prieto, J | 1 |
| Barbanel, G; Cambonie, G; Kamenka, JM | 1 |
| Bernardi, G; Bonsi, P; Calabresi, P; Centonze, D; Conquet, F; Gubellini, P; Picconi, B; Pisani, A | 1 |
| Beaver, CJ; Daw, NW; Ji, Q; Jin, XT | 1 |
| Johnson, SW; Zheng, F | 1 |
| Baskys, A; Blaabjerg, M; Fang, L; Zimmer, J | 1 |
| Collett, VJ; Collingridge, GL | 1 |
| Brambilla Bas, M; Luccini, E; Musante, V; Neri, E; Pittaluga, A; Raiteri, M; Severi, P | 1 |
| Ano, M; Hashimotodani, Y; Kano, M; Ohno-Shosaku, T; Takeda, S; Tsubokawa, H | 1 |
| Bashir, ZI; Collett, VJ; Collingridge, GL; Gladding, CM; Jia, Z; Molnár, E | 1 |
| Chiarugi, A; Formentini, L; Gerace, E; Landucci, E; Moroni, F; Pellegrini-Giampietro, DE; Scartabelli, T | 1 |
| Canonico, PL; Genazzani, AA; Lim, D; Mapelli, L; Moccia, F | 1 |
| Berlinguer Palmini, R; Di Luca, M; Gardoni, F; Gerace, E; Iezzi, D; Landucci, E; Mannaioni, G; Moroni, F; Pellegrini-Giampietro, DE; Scartabelli, T; Zianni, E | 1 |
| Bräuner-Osborne, H; Egebjerg, J; Krogsgaard-Larsen, P; Madsen, U; Nielsen, EO | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
1 review(s) available for 3,5-dihydroxyphenylglycine and n-methylaspartate
| Article | Year |
|---|---|
Ligands for glutamate receptors: design and therapeutic prospects.
Topics: Animals; Drug Design; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Humans; Ligands; N-Methylaspartate; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Synapses | 2000 |
23 other study(ies) available for 3,5-dihydroxyphenylglycine and n-methylaspartate
| Article | Year |
|---|---|
Enhancement of NMDA responses by group I metabotropic glutamate receptor activation in striatal neurones.
Topics: Animals; Cycloleucine; Excitatory Amino Acid Agents; Glycine; Male; N-Methylaspartate; Neostriatum; Neurons; Patch-Clamp Techniques; Protein Kinase C; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Resorcinols | 1997 |
Potentiation of NMDA and AMPA responses by group I mGluR in spinal cord motoneurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cycloleucine; Drug Synergism; Excitatory Amino Acid Agonists; Glycine; In Vitro Techniques; Male; Membrane Potentials; Motor Neurons; N-Methylaspartate; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols; Spinal Cord | 1997 |
Endogenous activation of metabotropic glutamate receptors contributes to burst frequency regulation in the lamprey locomotor network.
Topics: Animals; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Lampreys; Locomotion; Membrane Potentials; N-Methylaspartate; Nerve Net; Periodicity; Propionates; Receptors, Metabotropic Glutamate; Resorcinols; Spinal Cord; Synaptic Transmission | 1998 |
Mechanisms involved in the metabotropic glutamate receptor-enhancement of NMDA-mediated motoneurone responses in frog spinal cord.
Topics: Amino Acids, Dicarboxylic; Aminobutyrates; Animals; Benzoates; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Chlorpromazine; Cycloleucine; Dose-Response Relationship, Drug; Drug Synergism; Egtazic Acid; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; GTP-Binding Proteins; In Vitro Techniques; Kynurenic Acid; Magnesium; Membrane Potentials; Motor Neurons; N-Methylaspartate; Neuroprotective Agents; Pertussis Toxin; Rana pipiens; Receptors, Metabotropic Glutamate; Reflex; Resorcinols; Second Messenger Systems; Spinal Cord; Sulfonamides; Tetrodotoxin; Thapsigargin; Virulence Factors, Bordetella | 1999 |
[The ameliorating effects of a novel NC-1900 on impairments of learning/memory caused by glutamic acid].
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Arginine Vasopressin; Avoidance Learning; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Kainic Acid; Learning Disabilities; Male; Memory Disorders; Mice; Mice, Inbred Strains; N-Methylaspartate; Neuromuscular Depolarizing Agents; Oligopeptides; Pyrrolidonecarboxylic Acid; Rats; Rats, Sprague-Dawley; Resorcinols | 1999 |
Motor stimulation following bilateral injection of the group-I metabotropic glutamate receptor agonist into the dorsal striatum of rats: evidence against dependence on ionotropic glutamate receptors.
Topics: Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Kainic Acid; Male; Microinjections; Motor Activity; N-Methylaspartate; Neostriatum; Neurons; Piperazines; Quinoxalines; Rats; Rats, Wistar; Receptors, Glutamate; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Resorcinols; Stimulation, Chemical | 2000 |
N-methyl-D-aspartate but not glutamate induces the release of hydroxyl radicals in the neonatal rat: modulation by group I metabotropic glutamate receptors.
Topics: Animals; Animals, Newborn; Corpus Striatum; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Hydroxybenzoates; Hydroxyl Radical; Hypoxia-Ischemia, Brain; Ibotenic Acid; Indans; Microdialysis; N-Methylaspartate; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Resorcinols | 2000 |
Age-related decline in the functional response of striatal group I mGlu receptors.
Topics: Aging; Animals; Dopamine; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glycine; Hydrolysis; Male; Microdialysis; N-Methylaspartate; Neostriatum; Neurons; Phosphatidylinositols; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols | 2000 |
Role of Ca2+ stores in metabotropic L-glutamate receptor-mediated supralinear Ca2+ signaling in rat hippocampal neurons.
Topics: Action Potentials; Animals; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Signaling; Cells, Cultured; Contraindications; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Extracellular Space; Glycine; Hippocampus; N-Methylaspartate; Neuroglia; Neurons; Patch-Clamp Techniques; Potassium; Rats; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Resorcinols | 2000 |
An activity-dependent switch from facilitation to inhibition in the control of excitotoxicity by group I metabotropic glutamate receptors.
Topics: Animals; Cells, Cultured; Cerebral Cortex; Enzyme Activation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Mice; N-Methylaspartate; Nerve Degeneration; Neural Inhibition; Neuroprotective Agents; Neurotoxins; Protein Kinase C; Quisqualic Acid; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Time Factors | 2001 |
Glutamate inhibition of NMDA-induced hydroxyl radical release: an ontogenic study in rat.
Topics: Aging; Animals; Animals, Newborn; Brain; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Hydroxyl Radical; Microdialysis; N-Methylaspartate; Neurons; Neurotoxins; Oxidative Stress; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Resorcinols; Salicylates | 2001 |
Metabotropic glutamate receptor 5 mediates the potentiation of N-methyl-D-aspartate responses in medium spiny striatal neurons.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Action Potentials; Animals; Anticonvulsants; Benzoates; Cyclopropanes; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Mice; Mice, Knockout; Muscarine; Muscarinic Agonists; N-Methylaspartate; Neostriatum; Neurons; Phenylacetates; Pyridines; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Resorcinols; Synaptic Transmission | 2001 |
Effect of the group I metabotropic glutamate agonist DHPG on the visual cortex.
Topics: Action Potentials; Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cats; Drug Synergism; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; N-Methylaspartate; Organ Culture Techniques; Phenylacetates; Presynaptic Terminals; Rats; Receptors, Metabotropic Glutamate; Resorcinols; Visual Cortex | 2001 |
Group I metabotropic glutamate receptor-mediated enhancement of dopamine cell burst firing in rat ventral tegmental area in vitro.
Topics: Action Potentials; Animals; Apamin; Benzoates; Biological Clocks; Cycloleucine; Dopamine; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Male; Membrane Potentials; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Rats; Receptors, Metabotropic Glutamate; Resorcinols; Ventral Tegmental Area | 2002 |
Neuroprotection against NMDA excitotoxicity by group I metabotropic glutamate receptors is associated with reduction of NMDA stimulated currents.
Topics: Animals; Cells, Cultured; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; In Vitro Techniques; N-Methylaspartate; Neurons; Neurotoxins; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols | 2003 |
Interactions between NMDA receptors and mGlu5 receptors expressed in HEK293 cells.
Topics: Animals; Arsenicals; Cell Line; Drug Synergism; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Gene Expression; Genistein; Glycine; Humans; N-Methylaspartate; Phosphorylation; Protein-Tyrosine Kinases; Rats; Receptor Cross-Talk; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Recombinant Fusion Proteins; Resorcinols; Staurosporine; Thapsigargin; Transfection; Tyrosine; Vanadates | 2004 |
Functional interactions between presynaptic NMDA receptors and metabotropic glutamate receptors co-expressed on rat and human noradrenergic terminals.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Chromones; Female; Glycine; Hippocampus; Humans; Male; N-Methylaspartate; Norepinephrine; Presynaptic Terminals; Protein Binding; Rats; Rats, Sprague-Dawley; Receptor Cross-Talk; Receptor, Metabotropic Glutamate 5; Receptors, AMPA; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Presynaptic; Resorcinols; Synaptosomes; Tritium | 2007 |
Endocannabinoid signalling triggered by NMDA receptor-mediated calcium entry into rat hippocampal neurons.
Topics: Animals; Animals, Newborn; Calcium Channels; Calcium Signaling; Cannabinoid Receptor Modulators; Cells, Cultured; Chelating Agents; Dose-Response Relationship, Drug; Egtazic Acid; Endocannabinoids; Excitatory Amino Acid Agonists; Glycine; GTP-Binding Protein alpha Subunits, Gq-G11; Hippocampus; Inhibitory Postsynaptic Potentials; Lipoprotein Lipase; Morpholines; Muscarinic Agonists; N-Methylaspartate; Neurons; Oxotremorine; Phospholipase C beta; Pyrazoles; Rats; Receptor, Cannabinoid, CB1; Receptors, Metabotropic Glutamate; Receptors, Muscarinic; Receptors, N-Methyl-D-Aspartate; Resorcinols | 2007 |
Tyrosine dephosphorylation regulates AMPAR internalisation in mGluR-LTD.
Topics: Amino Acid Sequence; Animals; Endocytosis; Excitatory Amino Acid Agonists; Female; Glycine; Hippocampus; Long-Term Synaptic Depression; Molecular Sequence Data; N-Methylaspartate; Phosphorylation; Protein Subunits; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Metabotropic Glutamate; Resorcinols; Sequence Alignment; Synapses; Tyrosine | 2009 |
Mild activation of poly(ADP-ribose) polymerase (PARP) is neuroprotective in rat hippocampal slice models of ischemic tolerance.
Topics: Amino Acid Chloromethyl Ketones; Animals; Caspase 3; Caspase 7; Caspase Inhibitors; Cell Death; Cell Hypoxia; Cells, Cultured; Glucose; Glycine; Hippocampus; Ischemic Preconditioning; Isoquinolines; MAP Kinase Signaling System; N-Methylaspartate; Neurons; Neuroprotective Agents; Phenanthrenes; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Rats; Rats, Wistar; Resorcinols; Thiophenes | 2012 |
Neuronal Activity-Dependent Activation of Astroglial Calcineurin in Mouse Primary Hippocampal Cultures.
Topics: Animals; Astrocytes; Calcineurin; Calcium; Cell Nucleus; Cells, Cultured; Cytosol; Genetic Vectors; Glycine; Hippocampus; Long-Term Potentiation; Mice, Inbred C57BL; Models, Biological; N-Methylaspartate; Neuroglia; Neurons; Receptor, Metabotropic Glutamate 5; Reproducibility of Results; Resorcinols | 2018 |
Differential mechanisms of tolerance induced by NMDA and 3,5-dihydroxyphenylglycine (DHPG) preconditioning.
Topics: Animals; Cell Hypoxia; Drug Tolerance; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glucose; Glycine; Hippocampus; Ischemic Preconditioning; Male; N-Methylaspartate; Neuroprotection; Organ Culture Techniques; Rats; Rats, Wistar; Receptors, AMPA; Resorcinols | 2020 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |