3,5-dihydroxyphenylglycine has been researched along with glycine in 288 studies
| Studies (3,5-dihydroxyphenylglycine) | Trials (3,5-dihydroxyphenylglycine) | Recent Studies (post-2010) (3,5-dihydroxyphenylglycine) | Studies (glycine) | Trials (glycine) | Recent Studies (post-2010) (glycine) |
|---|---|---|---|---|---|
| 301 | 1 | 61 | 35,163 | 756 | 8,415 |
| 22 | 0 | 10 | 35,163 | 756 | 8,415 |
| Protein | Taxonomy | 3,5-dihydroxyphenylglycine (IC50) | glycine (IC50) |
|---|---|---|---|
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | 1.4852 | |
| Sodium- and chloride-dependent glycine transporter 1 | Homo sapiens (human) | 106 | |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | 0.3253 | |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | 0.3253 | |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | 0.3253 | |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | 0.3253 | |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | 0.3253 | |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | 0.3253 | |
| Sodium- and chloride-dependent glycine transporter 2 | Homo sapiens (human) | 128 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 75 (26.04) | 18.2507 |
| 2000's | 145 (50.35) | 29.6817 |
| 2010's | 63 (21.88) | 24.3611 |
| 2020's | 5 (1.74) | 2.80 |
| Authors | Studies |
|---|---|
| Hayashi, M; Hirose, E; Ito, I; Kohda, A; Mitsunaga, S; Sugiyama, H; Tanabe, S | 1 |
| Baker, SR; Goldsworthy, JS; Johnson, BG; Salhoff, CR; Schoepp, DD; Wright, RA | 1 |
| Conn, PJ; Gereau, RW; Winder, DG | 1 |
| Conn, PJ; Winder, DG | 1 |
| Armstrong, PW; Forster, C; Naik, G | 1 |
| Baker, SR; Goldsworthy, J; Johnson, BG; Salhoff, CR; Schoepp, DD | 1 |
| Dakak, NA; Eisenhofer, G; Elam, M; Friberg, P; Rundquist, B; Waagstein, F | 1 |
| Headley, PM; Jones, MW | 1 |
| Berlin, I; Launay, JM; Olivares, R; Puech, AJ; Said, S; Spreux-Varoquaux, O | 1 |
| Alexander, SP; Kendall, DA; Neil, KE | 1 |
| Johnson, BG; Monn, JA; Schoepp, DD | 1 |
| Brown, RE; Reymann, KG | 1 |
| Faden, AI; Fan, L; Mukhin, A | 1 |
| Manahan-Vaughan, D; Reymann, KG | 1 |
| DiMicco, J; Monroe, AJ | 1 |
| Burnett, JP; Desai, MA; Mayne, NG; Schoepp, DD | 1 |
| Belagaje, R; Burnett, JP; Johnson, BG; Mayne, NG; Monn, JA; Salhoff, CR; Schoepp, DD; Wright, RA; Wu, S | 1 |
| Coderre, TJ; Fisher, K | 1 |
| Bernardi, G; Calabresi, P; Centonze, D; Pisani, A | 2 |
| Brazelton, AD; Comery, TA; Eberwine, J; Greenough, WT; Irwin, SA; Klintsova, AY; Miyashiro, K; Patel, B; Spencer, CM; Weiler, IJ | 1 |
| Albin, RL; Frey, KA; Kearney, JA | 1 |
| O'Connor, JJ; O'Leary, DM | 2 |
| Blanc, EM; Kelly, JF; Mark, RJ; Mattson, MP; Waeg, G | 1 |
| Faden, AI; Ivanova, SA; Mukhin, AG | 1 |
| de Mendonça, A; Ribeiro, JA | 1 |
| Bordi, F; Corsi, M; Ugolini, A | 1 |
| Balcar, VJ; Ong, WY | 1 |
| Abbott, A; Lacey, MG; Wigmore, MA | 1 |
| DiJulio, N; Gruol, DL; Parsons, KL | 1 |
| Caciagli, F; Caruso, A; Casabona, G; Ciccarelli, R; Condorelli, DF; Di Iorio, P; Nicoletti, F; Spinella, F; Sureda, FX | 1 |
| Hounsgaard, J; Svirskis, G | 1 |
| Herrero, I; Miras-Portugal, MT; Sánchez-Prieto, J | 1 |
| Birch, PJ; Blackburn-Munro, G; Bountra, C; Dickinson, T; Fleetwood-Walker, SM; Sparrow, H; Young, MR | 1 |
| Camón, L; de Vera, N; Martínez, E; Vives, P | 1 |
| Cassidy, EM; O'Connor, JJ; O'Leary, DM | 1 |
| Coderre, TJ; Dray, A; Fisher, K; Fundytus, ME; Henry, JL | 1 |
| Abraham, WC; Cohen, AS; Raymond, CR | 1 |
| Bleuel, Z; Cartmell, J; Goepfert, F; Kemp, JA; Knoflach, F; Mutel, V; Pink, JR; Richards, JG; Schaffhauser, H; Wichmann, J | 1 |
| Balázs, R; Chun, Y; Cotman, CW; Miller, S; O'Toole, J | 1 |
| Alford, S; Cochilla, AJ | 1 |
| Dickenson, AH; Stanfa, LC | 1 |
| Carfì, M; Cozzi, A; Leonardi, P; Lombardi, G; Moroni, F; Pellicciari, R; Sourtcheva, S | 1 |
| Bijak, M; Brański, P; Pałucha, A; Pilc, A; Tokarski, K | 1 |
| Conn, PJ; Peavy, RD | 1 |
| Chu, Z; Hablitz, JJ | 1 |
| Bergold, PJ; Merlin, LR; Wong, RK | 1 |
| Narita, S | 1 |
| Johnson, BG; Monn, JA; Salhoff, CR; Schoepp, DD; Wright, RA | 1 |
| Albin, RL; Becker, JB; Frey, KA; Kearney, JA | 1 |
| Anderson, H; Blackburn-Munro, G; Dickinson, T; Fleetwood-Walker, SM; Johnson, MJ; Nakalembe, I; Young, MR | 1 |
| El Manira, A; Grillner, S; Krieger, P | 1 |
| Bernardi, G; Spadoni, F; Stefani, A | 1 |
| Agrawal, SK; Fehlings, MG; Theriault, E | 1 |
| Lerma, J; Rodríguez-Moreno, A; Sánchez-Prieto, J; Sistiaga, A | 1 |
| Bortolotto, ZA; Collingridge, GL; Doherty, AJ; Fitzjohn, SM; Kingston, AE; Lodge, D; Ornstein, PL; Palmer, MJ; Schoepp, DD | 1 |
| Dalby, NO; Thomsen, C | 1 |
| Conquet, F; Herrero, I; Sánchez-Prieto, J; Sistiaga, A | 1 |
| Collingridge, GL; Doherty, AJ; Jane, DE | 1 |
| Davidoff, RA; Hackman, JC; Holohean, AM | 1 |
| Chamberlain, M; Johnson, MP; Kelly, GM | 1 |
| Pèzzola, A; Popoli, P; Reggio, R; Tiburzi, F | 1 |
| Bortolotto, ZA; Collingridge, GL | 1 |
| Albani-Torregrossa, S; Attucci, S; Marinozzi, M; Moroni, F; Pellegrini-Giampietro, DE; Pellicciari, R | 1 |
| Keele, NB; Neugebauer, V; Shinnick-Gallagher, P | 1 |
| Aggleton, JP; Bashir, ZI; Bortolotto, ZA; Brown, MW; Cho, K; Collingridge, GL; Conquet, F; McCaffery, B | 1 |
| Beart, PM; Jones, NM; Monn, JA; Widdop, RE | 1 |
| Bernardi, G; Guatteo, E; Knöpfel, T; Mercuri, NB | 1 |
| Mathis, C; Ungerer, A | 1 |
| Cozzi, A; Leonardi, P; Meli, E; Moroni, F; Pellegrini-Giampietro, DE; Pellicciari, R; Peruginelli, F | 1 |
| Gao, C; Hu, HZ; Liu, S; Ren, J; Wood, JD; Xia, Y | 1 |
| Herrero, I; Manahan-Vaughan, D; Reymann, KG; Sánchez-Prieto, J | 1 |
| Bijak, M; Zahorodna, A | 1 |
| Hirate, K; Nishikawa, T; Ohnishi, Y; Sato, T; Tanaka, K; Teramoto, T | 1 |
| Kaasik, A; Kalda, A; Pokk, P; Vassiljev, V; Zharkovsky, A | 1 |
| Bacon, G; Chen, Y; Clark, BP; Johnson, BG; Kallman, MJ; Kingston, AE; Schoepp, DD; Sher, E; Wright, RA | 1 |
| Dolan, S; Nolan, AM | 1 |
| Boxall, AR | 1 |
| Copani, A; Fisichella, G; Frati, C; Marchese, C; Nasca, MR; Nicoletti, F; Storto, M | 1 |
| Bianchi, R; Chuang, SC; Wong, RK | 1 |
| Sánchez-Prieto, J; Sistiaga, A | 2 |
| Croucher, MJ; Harris, JR; Jane, DE; Thomas, LS | 1 |
| Chapman, AG; Meldrum, BS; Nanan, K; Williams, M | 1 |
| Alojado, ME; Anchisi, D; Knöpfel, T; Strata, P; Tempia, F | 1 |
| Mao, L; Wang, JQ | 2 |
| Wiśniewski, K; Zalewska-Wińska, A | 1 |
| Barbanel, G; Cambonie, G; Kamenka, JM; Laplanche, L | 1 |
| Domenici, MR; Pèzzola, A; Pintor, A; Popoli, P; Potenza, RL; Reggio, R; Tiburzi, F | 1 |
| Cassidy, J; Davies, SN; Ross, FM; Wilson, M | 1 |
| Bernardi, G; Bonsi, P; Calabresi, P; Centonze, D; Giacomini, P; Pisani, A | 1 |
| Collingridge, GL; Irving, AJ; Martin, DJ; Rae, MG | 1 |
| Nagy, F; Voisin, DL | 1 |
| Bernardi, G; Bonsi, P; Calabresi, P; Centonze, D; Pisani, A | 1 |
| Hermans, E; Maloteaux, JM; Najimi, M; Page, G; Peeters, M | 1 |
| Gleason, EL; Kreimborg, KM; Lester, ML; Medler, KF | 1 |
| Karnup, S; Stelzer, A | 1 |
| Battaglia, G; Bruno, V; Ceña, V; Cespédes, VM; Copani, A; Flor, PJ; Galindo, MF; Gasparini, F; Kuhn, R; Nicoletti, F; Sánchez-Prieto, J | 1 |
| Gereau, RW; Karim, F; Wang, CC | 1 |
| Bernardi, G; Caputi, L; Guatteo, E; Mercuri, NB; Tozzi, A | 1 |
| Haworth, RA; Schomberg, SL; Su, G; Sun, D | 1 |
| Bear, MF; Huber, KM; Roder, JC | 1 |
| Barbanel, G; Cambonie, G; Kamenka, JM | 1 |
| Morsette, DJ; Sidorowicz, H; Sladek, CD | 1 |
| Ahmadi, H; Croucher, MJ; Harris, JR; Lawrence, V; Thomas, LS | 1 |
| Chapman, AG; Meldrum, BS; Talebi, A; Yip, PK | 1 |
| Conn, PJ; Mannaioni, G; Marino, MJ; Traynelis, SF; Valenti, O | 1 |
| Bianchi, R; Chuang, SC; Kim, D; Shin, HS; Wong, RK | 1 |
| Chamberlain, M; Johnson, MP; Kelly, G | 1 |
| Nicholson, GJ; Pelzer, S; Pfeifer, V; Recktenwald, J; Ries, J; Schefer, AB; Schröder, J; Shawky, RM; Wohlleben, W | 1 |
| Carlton, SM; Du, J; Komak, S; Zhou, S | 1 |
| Alojado, ME; Knöpfel, T; Strata, P; Tempia, F | 1 |
| Croucher, MJ; Gasparini, F; Jane, DE; Thomas, LS | 1 |
| Bernardi, G; Berretta, N; Mercuri, NB; Paolucci, E | 1 |
| Angehagen, M; Björklund, U; Hansson, E; Muyderman, H; Nilsson, M; Olsson, T; Sandberg, M | 1 |
| Bernardi, G; Bonsi, P; Calabresi, P; Centonze, D; Conquet, F; Gubellini, P; Picconi, B; Pisani, A | 1 |
| Beaver, CJ; Daw, NW; Ji, Q; Jin, XT | 1 |
| Nicoll, RA; Xiao, MY; Zhou, Q | 1 |
| Kelland, EE; Toms, NJ | 1 |
| Choe, ES; Wang, JQ | 1 |
| Bear, MF; Dong, X; Fallon, JR; Huber, KM; Philpot, BD; Snyder, EM | 1 |
| Baker, DA; Carson, D; Kalivas, PW; Swanson, CJ; Worley, PF | 1 |
| Bibbig, A; Buhl, EH; Kopell, N; LeBeau, FE; Traub, RD; Whittington, MA | 1 |
| Collingridge, GL; Fitzjohn, SM; May, JE; Morris, SA; Neeson, A; Palmer, MJ | 1 |
| Chen, H; Hubbard, BK; Tseng, CC; Walsh, CT | 1 |
| Merlin, LR | 1 |
| Bianchi, R; Chuang, SC; Conquet, F; Wong, RK; Young, SR; Zhao, W | 1 |
| Aiba, A; Kano, M; Tabata, T | 1 |
| Car, H; Wiśniewski, K | 1 |
| Abraham, WC; Ireland, DR | 1 |
| Behrens, MM; Choi, DW; Heidinger, V; Manzerra, P; Strasser, U; Wang, XQ; Yu, SP | 1 |
| Anderson, J; Correa, L; Lorrain, DS; Varney, M | 1 |
| Amalric, M; Breysse, N; Risterucci, C | 1 |
| Hadar, E; Rutecki, PA; Sayin, U; Yang, Y | 1 |
| Adwanikar, H; Faas, GC; Gereau, RW; Saggau, P | 1 |
| Bashir, ZI; Collingridge, GL; Kilpatrick, IC; Moult, PR; Schnabel, R | 1 |
| Greengard, P; Liu, F; Nairn, AC; Virshup, DM | 1 |
| Baker, RS; Chamberlain, MJ; Clark, BP; Griffey, K; Harris, JR; Johnson, BG; Johnson, MP; Kelly, G; Kingston, AE; Schoepp, DD; Tizzano, JT; Tomlinson, R; Wright, RA | 1 |
| Frondaroli, A; Grassi, S; Pettorossi, VE | 1 |
| Choroba, OW; Hong, H; Li, TL; Spencer, JB; Williams, DH | 1 |
| Charles, EH; Choroba, OW; Li, TL; Sandercock, AM; Spencer, JB; Williams, DH | 1 |
| Conn, PJ; Peavy, RD; Sorensen, SD | 1 |
| Johnson, SW; Zheng, F | 1 |
| Hsu, KS; Huang, CC; You, JL; Zho, WM | 1 |
| Conn, PJ; Mannaioni, G; Poisik, OV; Smith, Y; Traynelis, S | 1 |
| Berrino, L; Bianchi, R; de Novellis, V; Maione, S; Marabese, I; Palazzo, E; Rodella, L; Rossi, F | 1 |
| Hirano, T; Kengaku, M; Minami, I; Shigemoto, R; Smitt, PS | 1 |
| Brackmann, M; Braunewell, KH; Manahan-Vaughan, D | 1 |
| El Manira, A; Hess, D; Kettunen, P | 1 |
| Croucher, MJ; Fazal, A; Palmer, AM; Parker, F | 1 |
| Alreja, M; Hajszan, T; Leranth, C; Wu, M | 1 |
| Baskys, A; Blaabjerg, M; Fang, L; Zimmer, J | 1 |
| Mack, KJ; Malter, JS; Todd, PK | 1 |
| Kim, SJ; Kim, YS; Linden, DJ; Petralia, RS; Worley, PF; Yuan, JP | 1 |
| Christie, LA; Irving, AJ; Kylänpää, RA; McIntosh, SJ; Platt, B; White, AM | 1 |
| Sulzer, D; Zhang, H | 1 |
| Canales, JJ; Cauli, O; Elayadi, A; Errami, M; Felipo, V; Llansola, M | 1 |
| Chang, RS; Chen, TB; Conn, PJ; Duggan, ME; Ha, SN; Jacobson, MA; Lemaire, W; Lindsley, CW; O'Brien, JA; Pettibone, DJ; Sur, C; Williams, DL; Wisnoski, DD | 1 |
| Hsu, KS; Huang, CC; Wu, MY; You, JL | 1 |
| Artola, A; de Graan, PN; Gispen, WH; Kamal, A; Ramakers, GM; van Dam, EJ | 1 |
| Alreja, M; Hajszan, T; Leranth, C; Wu, M; Xu, C | 1 |
| Cho, HW; Choe, ES; Kang, HS; Kim, JY; Mao, L; Parelkar, NK; Wang, JQ | 1 |
| Aridor, M; Bielli, A; Fish, KN; Guzik, AK | 1 |
| Bischoff, D; Bister, B; Kittel, C; Nicholson, GJ; Pfeifer, V; Süssmuth, RD; Weist, S; Wohlleben, W | 1 |
| Karakossian, MH; Otis, TS | 1 |
| Bear, MF; Daly, CA; Gallagher, SM; Huber, KM | 1 |
| Collett, VJ; Collingridge, GL | 1 |
| Duvoisin, RM; Grandes, P; Kushmerick, C; Price, GD; Puente, N; Renden, R; Taschenberger, H; von Gersdorff, H; Wadiche, JI | 1 |
| Hou, L; Klann, E | 1 |
| Hashimoto, K; Kano, M; Katsuki, M; Kitano, J; Moriyoshi, K; Nakamura, K; Nakanishi, S; Nakao, K; Sato, M; Tabata, T | 1 |
| Nistri, A; Ostroumov, K; Sharifullina, E | 1 |
| Gruol, DL; Nelson, TE; Netzeband, JG | 1 |
| Base, CK; Bertaina-Anglade, V; de Vries, FE; Greenough, WT; Grossman, AW; Hatia, F; Khaliq, H; Kim, SH; Klintsova, AY; Lambers, FA; Spangler, CC; Weiler, IJ | 1 |
| Berman, Y; Carr, KD; Pan, Y | 1 |
| Arora, A; Choe, ES; Fibuch, EE; Liu, Z; Mao, L; Wang, JQ; Yang, L; Zhang, G | 1 |
| Aronica, E; Gorter, JA; Rozemuller, AJ; Troost, D; Yankaya, B | 1 |
| Barton, ME; Shannon, HE | 1 |
| Dianzani, C; Fantozzi, R; Lombardi, G; Miglio, G; Varsaldi, F | 1 |
| de Hemptinne, I; Hermans, E; Maloteaux, JM; Najimi, M; Tilleux, S; Vanhoutte, N; Vermeiren, C | 1 |
| Heinke, B; Sandkühler, J | 2 |
| Antion, MD | 1 |
| Andree, TH; Gong, X; Liu, F; Marquis, K; Reinhart, P; Zhang, G | 1 |
| Andree, TH; Bowlby, M; Gilbert, A; Hornby, G; Liu, F; Marquis, K; Park, K; Vasylyev, D; Zhang, G | 1 |
| Farinelli, F; Fesce, R; Gioglio, L; Martini, M; Prigioni, I; Rispoli, G; Rossi, ML; Rubbini, G; Russo, G | 1 |
| Azzi, M; Kougioumoutzakis, A; Lacaille, JC; Morin, F; Topolnik, L | 1 |
| Elvers, M; Horejschi, V; Kaltschmidt, B; Kaltschmidt, C; Korte, M; Lindecke, A; Pfeiffer, J; Prüllage, M; Widera, D; Zagrebelsky, M | 1 |
| Ambrosini, SS; Coderre, TJ | 1 |
| Ballanyi, K; Funk, GD; Ma, Y; Poon, BY; Ruangkittisakul, A; Schwarzacher, SW; Secchia, L | 1 |
| Lu, Y | 1 |
| Chen, Y; Conn, PJ; de Paulis, T; Goudet, C; Hemstapat, K; Nong, Y; Pin, JP | 1 |
| Dewey, WL; Gabra, BH; Kessler, FK; Ritter, JK; Smith, FL | 1 |
| Cauli, O; Felipo, V; Llansola, M; Mlili, N | 1 |
| Cauli, O; Felipo, V; Mlili, N; Rodrigo, R | 1 |
| Brambilla Bas, M; Luccini, E; Musante, V; Neri, E; Pittaluga, A; Raiteri, M; Severi, P | 1 |
| Ano, M; Hashimotodani, Y; Kano, M; Ohno-Shosaku, T; Takeda, S; Tsubokawa, H | 1 |
| Coderre, TJ; Scotland, PE | 1 |
| Bayliss, DA; Berg, AP; Sen, N | 1 |
| Carroll, FI; Dewey, WL; Gabra, BH; Navarro, HA; Smith, FL | 1 |
| Baker, S; Brioni, JD; Chang, R; EI-Kouhen, O; Gauvin, DM; Hernandez, G; Hollingsworth, PR; Honore, P; Lehto, SG; Moreland, RB; Stewart, AO; Zheng, G; Zhu, CZ | 1 |
| Hikichi, H; Iwahori, Y; Maehara, S; Murai, T; Ohta, H; Satow, A | 1 |
| Battaglia, G; Conti, V; Diaspro, A; Feligioni, M; Henley, JM; Musante, V; Neri, E; Pedrazzi, M; Pittaluga, A; Puliti, A; Ravazzolo, R; Usai, C | 1 |
| Bondar, G; Christensen, A; Dewing, P; Micevych, P | 1 |
| Dodt, HU; Eder, M; Rammes, G; Zieglgänsberger, W | 1 |
| Kalivas, PW; Pacchioni, AM; Vallone, J; Worley, PF | 1 |
| Del Negro, CA; Pace, RW | 1 |
| Bashir, ZI; Collett, VJ; Collingridge, GL; Gladding, CM; Jia, Z; Molnár, E | 1 |
| Couette, B; Dantec, C; Journot, L; Le Digarcher, A; Mangoni, ME; Moore-Morris, T; Nargeot, J; Negre, V; Varrault, A | 1 |
| Araneda, RC; Smith, RS; Weitz, CJ | 1 |
| Beart, PM; Farso, MC; O'Shea, RD | 1 |
| Hata, M; Hikichi, H; Inoue, T; Ito, S; Kawagoe-Takaki, H; Kawamoto, H; Kimura, T; Maehara, S; Murai, T; Ohta, H; Ozaki, S; Satow, A; Suzuki, G | 1 |
| Alger, BE; Lafourcade, CA; Zhang, L | 1 |
| Bezprozvanny, I; Herndon, E; Huynh, DP; Liu, J; Nelson, O; Pulst, SM; Tang, TS; Tu, H | 1 |
| Matsuda, H; Taketo, M | 1 |
| Chepkova, AN; Doreulee, N; Fleischer, W; Haas, HL; Kazmierczak, T; Sergeeva, OA | 1 |
| Kirschstein, T; Köhling, R; Rohde, M; Tokay, T | 1 |
| Hariri, OR; Kuo, J; Micevych, P | 1 |
| Chongthammakun, S; Viwatpinyo, K | 1 |
| Pertovaara, A; Viisanen, H | 1 |
| Fujita, Y; Fukurotani, K; Hosoguchi, M; Kano, M; Shimomura, T; Tabata, T | 1 |
| Kamei, C; Masuoka, T; Mikami, A | 1 |
| Feng, DD; Han, JZ; Li, C; Li, JF; Liu, HJ; Liu, XY; Liu, Y; Luo, ZQ; Shen, L; Xu, JP; Yue, SJ | 1 |
| Choi, S; Eom, JY; Hong, I; Kim, J; Lee, CJ; Lee, J; Lee, S; Park, S; Song, B | 1 |
| Beltramo, M; Brusa, R; Lozza, G; Mancini, I; Petrò, R; Reggiani, A; Scandroglio, P | 1 |
| Kim, SY; Park, ES; Youn, DH | 1 |
| Araque, A; Navarrete, M | 1 |
| Bennett, MV; Francesconi, A; Kumari, R; Takayasu, Y; Takeuchi, K; Zukin, RS | 1 |
| Holden, T; Kullmann, DM; Le Duigou, C | 1 |
| Kullmann, DM; Le Duigou, C | 1 |
| Aerts, JM; Ahmed, T; Balschun, D; Berckmans, D; Tambuyzer, T | 1 |
| Falck, JR; Gebremedhin, D; Hammock, BD; Harder, DR; Hwang, SH; Koehler, RC; Li, C; Liu, X; Roman, RJ | 1 |
| Raman, IM; Zheng, N | 1 |
| Cohen, MB; Ding, C; Gong, R; Hu, J; Liu, F; Lu, Y; Luo, M; Mann, E; Xu, F | 1 |
| An, B; Choi, S; Eom, KD; Hong, I; Kim, H; Kim, J; Lee, HW; Lee, J; Lee, S; Park, K; Park, S; Park, SH; Song, B | 1 |
| Addae, JI; Darlington, LG; Forrest, CM; Morris, BJ; Murthy, S; Stone, TW | 1 |
| Steketee, JD; Timmer, KM | 1 |
| Chen, X; Dai, H; Gao, J; Gu, L; Liang, X; Mou, S; Ni, Z; Qian, J; Wang, L; Wang, Q; Yan, Y | 1 |
| Huang, JQ; Lou, YJ; Pan, X; Zhang, YY; Zhou, LM; Zhu, DY | 1 |
| McGinty, JF; Schwendt, M; Sigmon, SA | 1 |
| Barbarese, E; Carson, JH; Ifrim, MF; Korza, G; Levin, M; Tatavarty, V; Yu, J | 1 |
| Lan, JQ; Lusardi, TA; MacDonald, IC; Saugstad, JA; Theofilas, P; Thompson, SJ | 1 |
| De Jesús-Burgos, M; Pérez-Acevedo, NL; Torres-Llenza, V | 1 |
| Belyakov, AV; Samoilov, MO; Semenov, DG; Tyul'kova, EI; Vataeva, LA | 1 |
| Arizono, M; Bannai, H; Enomoto, M; Matsu-Ura, T; Mikoshiba, K; Miyamoto, A; Nakamura, K; Nakamura, T; Niwa, F; Sherwood, MW | 1 |
| Dell'anno, MT; Fisone, G; Pallottino, S | 1 |
| Diana, M; Dieudonné, S; Dugué, GP; Rothman, JS; Rousseau, C; Schwartz, EJ; Silver, RA | 1 |
| Anna Rossi, PI; Bonanno, G; Bonifacino, T; Di Prisco, S; Giribaldi, F; Milanese, M; Pittaluga, A; Puliti, A; Tacchetti, C; Usai, C | 1 |
| Chiarugi, A; Formentini, L; Gerace, E; Landucci, E; Moroni, F; Pellegrini-Giampietro, DE; Scartabelli, T | 1 |
| Boccella, S; De Chiaro, M; de Novellis, V; Gatta, L; Giordano, C; Guida, F; Luongo, L; Maione, S; Marabese, I; Palazzo, E; Rossi, F; Siniscalco, D; Vita, D | 1 |
| Chen, Q; Cheng, HP; Guo, C; Sun, Q; Tang, TS; Wang, JQ; Wang, QC; Wang, X; Wang, Y | 1 |
| Johnson, SW; Shen, KZ | 1 |
| Davis, KN; Deadwyler, SA; Hampson, RE; Howlett, AC; McQuail, JA; Miller, F; Nicolle, MM | 1 |
| Gao, HQ; Liu, QS; Liu, X; Sun, D; Yu, F; Zhong, P | 1 |
| Lam, YW; Sherman, SM | 1 |
| Israely, I; Ramiro-Cortés, Y | 1 |
| Flockerzi, V; Freichel, M; Lu, Y; Thakur, DP; Tian, J; Zhu, MX; Zhu, Y | 1 |
| Charles, JR; Duva, MA; Lara, RL; Ramirez, GJ; Stanley, BG; Yang, CR | 1 |
| Ady, V; Chen, X; Dadak, S; Dusart, I; Fagni, L; Lambolez, B; Levenes, C; Perroy, J; Piochon, C; Tricoire, L | 1 |
| Copeland, CS; Jones, HE; Salt, TE; Sillito, AM | 1 |
| Foster, TC; Kumar, A | 1 |
| Liu, MG; Zhuo, M | 1 |
| Arreola, AC; Kimmey, BA; Pierce, RC; Schmidt, HD | 1 |
| Pan, YZ; Rutecki, PA | 1 |
| Youn, DH | 1 |
| Hsu, KS; Huang, CC; Lee, CC; Liang, YC | 1 |
| Charles, JR; Hernandez, E; Stanley, BG; Winter, A; Yang, CR | 1 |
| Chung, MK; Joseph, J; Lee, J; Ro, JY; Saloman, J | 1 |
| Dong, LD; Gao, F; Li, F; Miao, Y; Sun, XH; Wang, Z; Wu, J; Zhang, SH | 1 |
| Husin, A; Ismail, Z; Nik Ramli, NN; Omar, N; Siran, R | 1 |
| Chergui, K; Feng, ZJ; Zhang, X | 1 |
| Han, YE; Ho, WK; Kim, HH; Lee, D; Lee, KH; Lee, SH; Sohn, JW | 1 |
| Chen, X; Wang, YL; Wang, ZP | 1 |
| Battaglia, G; Bruno, V; Di Menna, L; Madonna, M; Mascio, G; Nicoletti, F; Notartomaso, S; Puliti, A; Romano, MR; Scarselli, P | 1 |
| Colavita, M; Drago, F; Lemercier, CE; Marsicano, G; Massa, F; Terral, G | 1 |
| Aiba, A; Harada, T; Hashimoto, K; Kano, M; Miyata, M; Nagumo, Y; Narushima, M; Uchigashima, M; Uesaka, N; Watanabe, M; Yagasaki, Y | 1 |
| Deng, S; Ding, J; Hsu, TT; Jiang, Q; Li, F; Li, WG; Li, Y; Liu, MG; Liu, YM; Shang, L; Xu, TL; Zhu, MX | 1 |
| Chen, A; Hu, WW; Jiang, XL; Li, H; Potegal, M | 1 |
| Seki, K; Yashiro, S | 1 |
| Chen, SR; Pan, HL; Xie, JD | 1 |
| Canonico, PL; Genazzani, AA; Lim, D; Mapelli, L; Moccia, F | 1 |
| Gerace, E; Landucci, E; Pellegrini-Giampietro, DE; Scartabelli, T | 1 |
| Berlinguer Palmini, R; Di Luca, M; Gardoni, F; Gerace, E; Iezzi, D; Landucci, E; Mannaioni, G; Moroni, F; Pellegrini-Giampietro, DE; Scartabelli, T; Zianni, E | 1 |
| Huang, H; Li, D; Lu, Y; Peng, K; Wang, X; Wang, Y | 1 |
| Berardo, C; Cagna, M; Di Pasqua, LG; Ferrigno, A; Richelmi, P; Siciliano, V; Vairetti, M | 1 |
| Barry, RL; Byun, NE; Conn, PJ; Gore, JC; Joffe, ME; Li, B; Lindsley, CW; Luessen, DJ; Maksymetz, J; Niswender, CM | 1 |
| Bräuner-Osborne, H; Egebjerg, J; Krogsgaard-Larsen, P; Madsen, U; Nielsen, EO | 1 |
2 review(s) available for 3,5-dihydroxyphenylglycine and glycine
| Article | Year |
|---|---|
(S)-3,5-DHPG: a review.
Topics: Action Potentials; Alzheimer Disease; Animals; Behavior, Animal; Cognition Disorders; Cyclic AMP; Excitatory Amino Acid Agonists; Glycine; Models, Animal; Neurotransmitter Agents; Receptors, Metabotropic Glutamate; Resorcinols; Second Messenger Systems; Stereoisomerism | 2002 |
Ligands for glutamate receptors: design and therapeutic prospects.
Topics: Animals; Drug Design; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Humans; Ligands; N-Methylaspartate; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Synapses | 2000 |
1 trial(s) available for 3,5-dihydroxyphenylglycine and glycine
| Article | Year |
|---|---|
Monoamine oxidase A and B activities in heavy smokers.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Aged; Blood Platelets; Blood Pressure; Cotinine; Depression; Female; Glycine; Humans; Levodopa; Male; Middle Aged; Monoamine Oxidase; Norepinephrine; Resorcinols; Smoking | 1995 |
285 other study(ies) available for 3,5-dihydroxyphenylglycine and glycine
| Article | Year |
|---|---|
3,5-Dihydroxyphenyl-glycine: a potent agonist of metabotropic glutamate receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; Animals; Cycloleucine; Egtazic Acid; Glycine; Hippocampus; In Vitro Techniques; Male; Oocytes; Potassium Channels; Quinoxalines; Rats; Rats, Wistar; Receptors, Glutamate; Resorcinols; RNA, Messenger; Xenopus | 1992 |
Second-messenger responses in brain slices to elucidate novel glutamate receptors.
Topics: Animals; Cycloleucine; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glycine; Guinea Pigs; Hippocampus; Rats; Receptors, Glutamate; Receptors, Metabotropic Glutamate; Resorcinols; Second Messenger Systems | 1995 |
Pharmacological differentiation of the effects of co-activation of beta-adrenergic and metabotropic glutamate receptors in rat hippocampus.
Topics: Adrenergic beta-Agonists; Animals; Cyclopropanes; Evoked Potentials; Glycine; Hippocampus; In Vitro Techniques; Isoproterenol; Male; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Receptors, Metabotropic Glutamate; Resorcinols; Synapses; Synaptic Transmission | 1995 |
Metabotropic glutamate receptor (mGluR)-mediated potentiation of cyclic AMP responses does not require phosphoinositide hydrolysis: mediation by a group II-like mGluR.
Topics: Animals; Brain; Calcium; Calcium-Transporting ATPases; Cyclic AMP; Cycloleucine; Glycine; Hydrolysis; In Vitro Techniques; Intracellular Membranes; Neurotoxins; Phosphatidylinositols; Protein Kinase C; Rats; Receptors, Metabotropic Glutamate; Resorcinols; Terpenes; Thapsigargin | 1995 |
Noradrenaline biosynthesis and metabolism during development and recovery from pacing-induced heart failure in the dog.
Topics: Animals; Cardiac Output, Low; Cardiac Pacing, Artificial; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Dogs; Electrochemistry; Glycine; Heart Ventricles; Male; Myocardium; Norepinephrine; Resorcinols | 1994 |
3,5-dihydroxyphenylglycine is a highly selective agonist for phosphoinositide-linked metabotropic glutamate receptors in the rat hippocampus.
Topics: Aging; Amino Acids, Dicarboxylic; Animals; Animals, Newborn; Colforsin; Cyclic AMP; Cycloleucine; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; In Vitro Techniques; Kinetics; Male; Neurotoxins; Phosphatidylinositols; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Resorcinols; Second Messenger Systems | 1994 |
Cardiac noradrenergic function one year following cardiac transplantation.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Aged; Angina Pectoris; Blood Pressure; Cardiac Catheterization; Dihydroxyphenylalanine; Exercise Test; Glycine; Heart; Heart Rate; Heart Transplantation; Humans; Male; Middle Aged; Myocardium; Norepinephrine; Resorcinols; Sympathetic Nervous System | 1993 |
Interactions between metabotropic and ionotropic glutamate receptor agonists in the rat spinal cord in vivo.
Topics: Action Potentials; Animals; Blood Pressure; Cycloleucine; Electrophoresis; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Male; Neurons; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols; Spinal Cord | 1995 |
Coupling of metabotropic glutamate receptors to phosphoinositide mobilisation and inhibition of cyclic AMP generation in the guinea-pig cerebellum.
Topics: 2-Chloroadenosine; Animals; Cerebellum; Colforsin; Cyclic AMP; Cycloleucine; Female; Glutamic Acid; Glycine; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Phosphatidylinositols; Receptors, Metabotropic Glutamate; Resorcinols | 1996 |
(1 S,3 R)-1-aminocyclopentane-1,3-dicarboxylic acid-induced increases in cyclic AMP formation in the neonatal rat hippocampus are mediated by a synergistic interaction between phosphoinositide- and inhibitory cyclic AMP-coupled mGluRs.
Topics: Animals; Animals, Newborn; Cyclic AMP; Cycloleucine; Excitatory Amino Acid Antagonists; Female; Glycine; Hippocampus; In Vitro Techniques; Male; Phosphatidylinositols; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols | 1996 |
Class I metabotropic glutamate receptor agonists do not facilitate the induction of long-term potentiation in the dentate gyrus of the rat in vitro.
Topics: Animals; Azetidinecarboxylic Acid; Dentate Gyrus; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Long-Term Potentiation; Male; Picrotoxin; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols | 1995 |
Activation of metabotropic glutamate receptor subtype mGluR1 contributes to post-traumatic neuronal injury.
Topics: Animals; Benzoates; Cell Death; Coculture Techniques; Excitatory Amino Acid Antagonists; Glycine; Immunoblotting; Nerve Tissue; Neuroglia; Neurons; Neuroprotective Agents; Oligonucleotides, Antisense; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols | 1996 |
Metabotropic glutamate receptor subtype agonists facilitate long-term potentiation within a distinct time window in the dentate gyrus in vivo.
Topics: Animals; Azetidinecarboxylic Acid; Dentate Gyrus; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Agonists; Glycine; Long-Term Potentiation; Male; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols; Time Factors | 1996 |
Stimulation of metabotropic glutamate receptors in the dorsomedial hypothalamus elevates heart rate in rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cycloleucine; Dose-Response Relationship, Drug; Glycine; Heart Rate; Hypothalamus, Middle; Male; Microinjections; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Resorcinols; Tachycardia | 1996 |
Pharmacological characterization of desensitization in a human mGlu1 alpha-expressing non-neuronal cell line co-transfected with a glutamate transporter.
Topics: Amino Acid Transport System X-AG; Animals; Carrier Proteins; Cell Line; Cycloleucine; Excitatory Amino Acid Antagonists; Glycine; Glycoproteins; Humans; Hydrolysis; Inosine Triphosphate; Inositol; Neurotoxins; Phosphatidylinositols; Rats; Receptors, Metabotropic Glutamate; Resorcinols | 1996 |
The novel metabotropic glutamate receptor agonist 2R,4R-APDC potentiates stimulation of phosphoinositide hydrolysis in the rat hippocampus by 3,5-dihydroxyphenylglycine: evidence for a synergistic interaction between group 1 and group 2 receptors.
Topics: Aging; Animals; Animals, Newborn; Brain; Cloning, Molecular; Colforsin; Cyclic AMP; Cycloleucine; Drug Synergism; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Humans; Inositol; Kinetics; Neuroprotective Agents; Phosphatidylinositols; Proline; Quisqualic Acid; Rats; Receptors, Metabotropic Glutamate; Recombinant Proteins; Resorcinols; Second Messenger Systems | 1996 |
The contribution of metabotropic glutamate receptors (mGluRs) to formalin-induced nociception.
Topics: Aminobutyrates; Analysis of Variance; Animals; Benzoates; Cycloleucine; Cyclopropanes; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Formaldehyde; Glycine; Male; Pain; Rats; Receptors, Metabotropic Glutamate; Resorcinols | 1996 |
Enhancement of NMDA responses by group I metabotropic glutamate receptor activation in striatal neurones.
Topics: Animals; Cycloleucine; Excitatory Amino Acid Agents; Glycine; Male; N-Methylaspartate; Neostriatum; Neurons; Patch-Clamp Techniques; Protein Kinase C; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Resorcinols | 1997 |
Fragile X mental retardation protein is translated near synapses in response to neurotransmitter activation.
Topics: Amino Acid Sequence; Animals; Antibodies; Antisense Elements (Genetics); Brain; Dendrites; DNA, Complementary; Excitatory Amino Acid Antagonists; Fragile X Mental Retardation Protein; Gene Library; Glycine; Humans; Kinetics; Molecular Sequence Data; Nerve Tissue Proteins; Neurons; Neurotransmitter Agents; Oligonucleotide Probes; Organ Specificity; Polyribosomes; Protein Biosynthesis; Rats; Receptors, Metabotropic Glutamate; Resorcinols; RNA-Binding Proteins; RNA, Messenger; Sequence Homology, Amino Acid; Synapses | 1997 |
Metabotropic glutamate agonist-induced rotation: a pharmacological, FOS immunohistochemical, and [14C]-2-deoxyglucose autoradiographic study.
Topics: Animals; Autoradiography; Basal Ganglia; Behavior, Animal; Caffeine; Carbon Radioisotopes; Cycloleucine; Deoxyglucose; Dopamine; Dopamine Agonists; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Glucose; Glycine; Immunohistochemistry; Male; Neuroprotective Agents; Proto-Oncogene Proteins c-fos; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Receptors, Muscarinic; Receptors, Purinergic P1; Resorcinols; Rotation; Salicylamides; Thalamic Nuclei; Xanthines | 1997 |
Potentiation of synaptic transmission in the rat dentate gyrus in vitro by (S)-3,5-dihydroxyphenylglycine ((S)-DHPG).
Topics: 2-Amino-5-phosphonovalerate; Animals; Benzoates; Dentate Gyrus; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Male; Rats; Resorcinols; Stimulation, Chemical; Synaptic Transmission | 1997 |
4-Hydroxynonenal, an aldehydic product of lipid peroxidation, impairs signal transduction associated with muscarinic acetylcholine and metabotropic glutamate receptors: possible action on G alpha(q/11).
Topics: Aldehydes; Animals; Antioxidants; Carbachol; Cerebral Cortex; Glycine; GTP Phosphohydrolases; GTP-Binding Proteins; Lipid Peroxidation; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Receptors, Muscarinic; Resorcinols; Signal Transduction; Sodium Fluoride | 1997 |
mGluR modulation of post-traumatic neuronal death: role of NMDA receptors.
Topics: Animals; Animals, Newborn; Brain Injuries; Cell Death; Cells, Cultured; Cerebral Cortex; Coculture Techniques; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glycine; Indans; L-Lactate Dehydrogenase; Models, Neurological; Neuroglia; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Resorcinols | 1997 |
Influence of metabotropic glutamate receptor agonists on the inhibitory effects of adenosine A1 receptor activation in the rat hippocampus.
Topics: Adenosine; Animals; Cycloleucine; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Glycine; Hippocampus; Protein Kinase C; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, Purinergic P1; Resorcinols | 1997 |
Potentiation of NMDA and AMPA responses by group I mGluR in spinal cord motoneurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cycloleucine; Drug Synergism; Excitatory Amino Acid Agonists; Glycine; In Vitro Techniques; Male; Membrane Potentials; Motor Neurons; N-Methylaspartate; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols; Spinal Cord | 1997 |
Group I metabotropic glutamate receptor agonist causes neurodegeneration in rat hippocampus.
Topics: Animals; Cerebral Ventricles; Dentate Gyrus; Glycine; Hippocampus; Injections, Intraventricular; Male; Pyramidal Cells; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols | 1997 |
Excitation of rat subthalamic nucleus neurones in vitro by activation of a group I metabotropic glutamate receptor.
Topics: Adenine Nucleotides; Affinity Labels; Animals; Benzoates; Cycloleucine; Cyclopropanes; Electrophysiology; Excitatory Amino Acid Antagonists; Glycine; Male; Neurons; Neuroprotective Agents; Pyridoxal; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols; Thalamic Nuclei | 1997 |
Acute ethanol alters calcium signals elicited by glutamate receptor agonists and K+ depolarization in cultured cerebellar Purkinje neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cells, Cultured; Cerebellar Cortex; Cycloleucine; Embryo, Mammalian; Ethanol; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Kainic Acid; Membrane Potentials; Potassium; Purkinje Cells; Rats; Receptors, Glutamate; Receptors, Metabotropic Glutamate; Resorcinols | 1997 |
Opposite influence of the metabotropic glutamate receptor subtypes mGlu3 and -5 on astrocyte proliferation in culture.
Topics: Animals; Astrocytes; Blotting, Western; Calcium; Cell Division; Cells, Cultured; Cyclopropanes; DNA; Excitatory Amino Acid Antagonists; Glycine; Polymerase Chain Reaction; Rats; Receptors, Metabotropic Glutamate; Resorcinols | 1997 |
Transmitter regulation of plateau properties in turtle motoneurons.
Topics: Animals; Atropine; Baclofen; Benzoates; Calcium Channels; Calcium Channels, L-Type; Cycloleucine; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Membrane Potentials; Motor Neurons; Muscarine; Nifedipine; Patch-Clamp Techniques; Receptors, Metabotropic Glutamate; Resorcinols; Spinal Cord; Tetraethylammonium; Tetrodotoxin; Turtles | 1998 |
Functional switch from facilitation to inhibition in the control of glutamate release by metabotropic glutamate receptors.
Topics: Animals; Calcium; Cerebral Cortex; Diglycerides; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Male; Potassium Channels; Protein Kinase C; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols; Staurosporine | 1998 |
Behavioural and electrophysiological evidence supporting a role for group I metabotropic glutamate receptors in the mediation of nociceptive inputs to the rat spinal cord.
Topics: Alanine; Animals; Antihypertensive Agents; Behavior, Animal; Benzothiadiazines; Cycloleucine; Electrophysiology; Excitatory Amino Acid Antagonists; Female; Glycine; Male; Mustard Plant; Neuroprotective Agents; Nociceptors; Pain; Phenylacetates; Plant Extracts; Plant Oils; Plants, Medicinal; Rats; Rats, Inbred Strains; Receptors, Metabotropic Glutamate; Resorcinols; Spinal Cord | 1997 |
Seizures and neuronal damage induced in the rat by activation of group I metabotropic glutamate receptors with their selective agonist 3,5-dihydroxyphenylglycine.
Topics: Analysis of Variance; Animals; Cerebral Ventricles; Cycloleucine; Excitatory Amino Acid Agonists; Glycine; Infusions, Parenteral; Male; Motor Activity; Neurons; Neuroprotective Agents; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols; Seizures | 1998 |
Group II and III metabotropic glutamate receptors modulate paired pulse depression in the rat dentate gyrus in vitro.
Topics: Amino Acids, Dicarboxylic; Aminobutyrates; Animals; Benzoates; Cycloleucine; Cyclopropanes; Dentate Gyrus; Evoked Potentials, Somatosensory; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; In Vitro Techniques; Neuroprotective Agents; Rats; Receptors, Metabotropic Glutamate; Resorcinols | 1997 |
In vivo antinociceptive activity of anti-rat mGluR1 and mGluR5 antibodies in rats.
Topics: Analgesics; Animals; Excitatory Amino Acid Antagonists; Glycine; Immunoglobulin G; Injections, Spinal; Male; Pain; Rats; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Spinal Cord | 1998 |
Priming of long-term potentiation induced by activation of metabotropic glutamate receptors coupled to phospholipase C.
Topics: Animals; Cycloleucine; Electric Stimulation; Estrenes; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; Neuroprotective Agents; Pyramidal Cells; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols; Synapses; Type C Phospholipases | 1998 |
Effect of metabotropic glutamate receptor activation on receptor-mediated cyclic AMP responses in primary cultures of rat striatal neurones.
Topics: Adenosine-5'-(N-ethylcarboxamide); Animals; Autoradiography; Cells, Cultured; Corpus Striatum; Cyclic AMP; Excitatory Amino Acid Agonists; Fluorescent Antibody Technique; Glutamic Acid; Glycine; Hydrolysis; In Situ Hybridization; Neurons; Phosphatidylinositols; Rats; Receptors, Metabotropic Glutamate; Resorcinols | 1998 |
Metabotropic glutamate receptor agonists potentiate cyclic AMP formation induced by forskolin or beta-adrenergic receptor activation in cerebral cortical astrocytes in culture.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Animals, Newborn; Astrocytes; Cells, Cultured; Colforsin; Cyclic AMP; Cycloleucine; Drug Synergism; Estrenes; Excitatory Amino Acid Agonists; Glycine; Neocortex; Phosphodiesterase Inhibitors; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Adrenergic, beta; Receptors, Metabotropic Glutamate; Resorcinols; Signal Transduction; Type C Phospholipases; Up-Regulation | 1998 |
Metabotropic glutamate receptor-mediated control of neurotransmitter release.
Topics: 4-Aminopyridine; Animals; Calcium; Cycloleucine; Electrophysiology; Excitatory Amino Acid Antagonists; Glycine; Lampreys; Membrane Potentials; Motor Neurons; Neuroprotective Agents; Neurotransmitter Agents; Potassium; Presynaptic Terminals; Receptors, Metabotropic Glutamate; Resorcinols; Ryanodine; Spinal Cord; Synaptic Transmission | 1998 |
Inflammation alters the effects of mGlu receptor agonists on spinal nociceptive neurones.
Topics: Animals; Carrageenan; Cycloleucine; Excitatory Amino Acid Antagonists; Glycine; Inflammation; Male; Neurons; Pain; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols; Spinal Cord; Supine Position | 1998 |
Presynaptic mGlu1 type receptors potentiate transmitter output in the rat cortex.
Topics: Animals; Benzoates; Bridged Bicyclo Compounds; Cycloleucine; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Indans; Microdialysis; Parietal Lobe; Rats; Receptors, Metabotropic Glutamate; Receptors, Presynaptic; Resorcinols | 1998 |
Antidepressant treatment influences group I of glutamate metabotropic receptors in slices from hippocampal CA1 region.
Topics: Action Potentials; Animals; Antidepressive Agents, Tricyclic; Cycloleucine; Electroshock; Excitatory Amino Acid Agonists; Glycine; Hippocampus; Imipramine; Inositol Phosphates; Male; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols | 1998 |
Phosphorylation of mitogen-activated protein kinase in cultured rat cortical glia by stimulation of metabotropic glutamate receptors.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Cerebral Cortex; Cycloleucine; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Flavonoids; Glycine; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase Kinases; Neuroglia; Neuroprotective Agents; Phosphorylation; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols; Tyrosine | 1998 |
Activation of group I mGluRs increases spontaneous IPSC frequency in rat frontal cortex.
Topics: Amino Acids, Dicarboxylic; Aminobutyrates; Animals; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Frontal Lobe; Glycine; Neural Inhibition; Neuroprotective Agents; Patch-Clamp Techniques; Pyramidal Cells; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols; Synaptic Transmission; Tetrodotoxin | 1998 |
Requirement of protein synthesis for group I mGluR-mediated induction of epileptiform discharges.
Topics: Action Potentials; Animals; Anisomycin; Brain Chemistry; Convulsants; Epilepsy; Excitatory Amino Acid Antagonists; Glycine; Guinea Pigs; Neurons; Periodicity; Picrotoxin; Protein Synthesis Inhibitors; Receptors, Metabotropic Glutamate; Resorcinols | 1998 |
[Pharmacological study on metabotropic glutamate receptors on trigeminal neurons].
Topics: Action Potentials; Animals; Cyclopropanes; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Motor Neurons; Neurons, Afferent; Propionates; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols; Trigeminal Nerve | 1998 |
Potent, stereoselective, and brain region selective modulation of second messengers in the rat brain by (+)LY354740, a novel group II metabotropic glutamate receptor agonist.
Topics: Adenosine-5'-(N-ethylcarboxamide); Animals; Brain; Bridged Bicyclo Compounds; Cyclic AMP; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Hydrolysis; Male; Phosphatidylinositols; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols; Second Messenger Systems; Stereoisomerism; Vasodilator Agents | 1998 |
The role of nigrostriatal dopamine in metabotropic glutamate agonist-induced rotation.
Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Methyltyrosine; Aminobutyrates; Animals; Corpus Striatum; Deoxyglucose; Desipramine; Dominance, Cerebral; Dopamine; Excitatory Amino Acid Agonists; Gene Expression Regulation; Genes, fos; Glycine; Indans; Male; Motor Activity; Nerve Tissue Proteins; Oxidopamine; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Reserpine; Resorcinols; Substantia Nigra; Superior Colliculi | 1998 |
Antisense ablation of type I metabotropic glutamate receptor mGluR1 inhibits spinal nociceptive transmission.
Topics: Animals; Antisense Elements (Genetics); Azetidinecarboxylic Acid; Behavior, Animal; Electrophysiology; Excitatory Amino Acid Agonists; Gene Deletion; Glycine; Male; Membrane Potentials; Mutagenesis; Nociceptors; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Spinal Cord; Synaptic Transmission | 1998 |
Endogenous activation of metabotropic glutamate receptors contributes to burst frequency regulation in the lamprey locomotor network.
Topics: Animals; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Lampreys; Locomotion; Membrane Potentials; N-Methylaspartate; Nerve Net; Periodicity; Propionates; Receptors, Metabotropic Glutamate; Resorcinols; Spinal Cord; Synaptic Transmission | 1998 |
Group I mGluRs modulate calcium currents in rat GP: functional implications.
Topics: Animals; Benzoates; Calcium Channel Blockers; Calcium Channels; Cycloleucine; Electric Conductivity; Excitatory Amino Acid Antagonists; Globus Pallidus; Glycine; Male; Neuroprotective Agents; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols | 1998 |
Role of group I metabotropic glutamate receptors in traumatic spinal cord white matter injury.
Topics: Age Factors; Animals; Astrocytes; Benzoates; Cycloleucine; Electrophysiology; Estrenes; Excitatory Amino Acid Antagonists; Glial Fibrillary Acidic Protein; Glycine; Immunohistochemistry; Male; Membrane Potentials; Nerve Fibers; Neuroprotective Agents; Phosphodiesterase Inhibitors; Pyrrolidinones; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols; Spinal Cord; Spinal Cord Injuries; Type C Phospholipases | 1998 |
Switch from facilitation to inhibition of excitatory synaptic transmission by group I mGluR desensitization.
Topics: Animals; Evoked Potentials; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; GTP-Binding Proteins; Hippocampus; In Vitro Techniques; Male; Models, Neurological; Nerve Endings; Neurons; Protein Kinase C; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols; Synaptic Transmission; Synaptosomes | 1998 |
The potent mGlu receptor antagonist LY341495 identifies roles for both cloned and novel mGlu receptors in hippocampal synaptic plasticity.
Topics: Aging; Amino Acids; Animals; Binding, Competitive; Cell Line; CHO Cells; Cloning, Molecular; Cricetinae; Cycloleucine; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Hippocampus; Humans; In Vitro Techniques; Long-Term Potentiation; Neuronal Plasticity; Rats; Receptors, Metabotropic Glutamate; Recombinant Proteins; Resorcinols; Transfection; Xanthenes | 1998 |
Roles of metabotropic glutamate receptor subtypes in modulation of pentylenetetrazole-induced seizure activity in mice.
Topics: Animals; Cerebral Ventricles; Cycloleucine; Excitatory Amino Acid Antagonists; Glycine; Indans; Infusions, Parenteral; Male; Mice; Mice, Inbred Strains; Pentylenetetrazole; Reaction Time; Resorcinols; Seizures | 1998 |
The metabotropic glutamate receptor 1 is not involved in the facilitation of glutamate release in cerebrocortical nerve terminals.
Topics: Adenosine; Animals; Cerebral Cortex; Diglycerides; Glutamic Acid; Glycine; Mice; Mice, Knockout; Nerve Endings; Phosphatidylinositols; Purinergic P1 Receptor Agonists; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Reference Values; Resorcinols; Synaptosomes; Time Factors | 1998 |
Antagonist activity of alpha-substituted 4-carboxyphenylglycine analogues at group I metabotropic glutamate receptors expressed in CHO cells.
Topics: Animals; Benzoates; Binding, Competitive; Calcium; CHO Cells; Cricetinae; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Phenylacetates; Receptors, Metabotropic Glutamate; Resorcinols | 1999 |
Mechanisms involved in the metabotropic glutamate receptor-enhancement of NMDA-mediated motoneurone responses in frog spinal cord.
Topics: Amino Acids, Dicarboxylic; Aminobutyrates; Animals; Benzoates; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Chlorpromazine; Cycloleucine; Dose-Response Relationship, Drug; Drug Synergism; Egtazic Acid; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; GTP-Binding Proteins; In Vitro Techniques; Kynurenic Acid; Magnesium; Membrane Potentials; Motor Neurons; N-Methylaspartate; Neuroprotective Agents; Pertussis Toxin; Rana pipiens; Receptors, Metabotropic Glutamate; Reflex; Resorcinols; Second Messenger Systems; Spinal Cord; Sulfonamides; Tetrodotoxin; Thapsigargin; Virulence Factors, Bordetella | 1999 |
Phosphoinositide hydrolysis in vivo with group I metabotropic glutamate receptor agonists.
Topics: Amino Acids; Animals; Brain Chemistry; Cerebellum; Cycloleucine; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Hydrolysis; Injections, Intraventricular; Male; Neuroprotective Agents; Phenylacetates; Phosphatidylinositols; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols; Tritium; Type C Phospholipases; Xanthenes | 1999 |
Selective agonists of metabotropic glutamate receptors elicit significant EEG effects when infused in the nucleus accumbens of rats.
Topics: Amino Acids, Dicarboxylic; Animals; Behavior, Animal; Electroencephalography; Excitatory Amino Acid Agonists; Glycine; Male; Nucleus Accumbens; Propionates; Rats; Rats, Wistar; Receptors, Glutamate; Resorcinols; Seizures | 1999 |
Evidence that a novel metabotropic glutamate receptor mediates the induction of long-term potentiation at CA1 synapses in the hippocampus.
Topics: Animals; Benzoates; Cycloleucine; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Rats; Receptors, Metabotropic Glutamate; Resorcinols; Synapses | 1999 |
Antagonist pharmacology of metabotropic glutamate receptors coupled to phospholipase D activation in adult rat hippocampus: focus on (2R,1'S,2'R,3'S)-2-(2'-carboxy-3'-phenylcyclopropyl)glycine versus 3, 5-dihydroxyphenylglycine.
Topics: Animals; Cyclopropanes; Enzyme Activation; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; In Vitro Techniques; Phospholipase D; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols; Stereoisomerism | 1999 |
Differential effects of metabotropic glutamate receptor antagonists on bursting activity in the amygdala.
Topics: Amygdala; Animals; Benzoates; Cycloleucine; Electrophysiology; Epilepsy; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Kindling, Neurologic; Male; Neurons; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols; Synapses | 1999 |
Potentiation of synaptic transmission by (S)-3,5-dihydroxy phenylglycine in the rat dentate gyrus in vitro: a role for voltage dependent calcium channels and protein kinase C.
Topics: Animals; Calcium Channel Blockers; Dentate Gyrus; Excitatory Amino Acid Antagonists; Glycine; Phenylacetates; Protein Kinase C; Rats; Receptors, Metabotropic Glutamate; Resorcinols; Synaptic Transmission | 1999 |
Metabotropic glutamate receptors and cell-type-specific vulnerability in the striatum: implication for ischemia and Huntington's disease.
Topics: Animals; Brain Ischemia; Calcium Channels; Cell Communication; Cells, Cultured; Cerebral Cortex; Cholinergic Fibers; Corpus Striatum; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Glycine; Huntington Disease; Interneurons; Male; Membrane Potentials; Protein Kinase C; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Glutamate; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Resorcinols | 1999 |
Synaptic depression induced by pharmacological activation of metabotropic glutamate receptors in the perirhinal cortex in vitro.
Topics: Animals; Cycloleucine; Cyclopropanes; Electric Stimulation; Entorhinal Cortex; Excitatory Amino Acid Agonists; Female; Glutamic Acid; Glycine; Hippocampus; Male; Neocortex; Neuronal Plasticity; Organ Culture Techniques; Propionates; Rats; Rats, Inbred Strains; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols; Synaptic Transmission; Temporal Lobe | 1999 |
Type I and II metabotropic glutamate receptors mediate depressor and bradycardic actions in the nucleus of the solitary tract of anaesthetized rats.
Topics: Anesthesia; Animals; Blood Pressure; Bradycardia; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Heart Rate; Indans; Male; Microinjections; Proline; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols; Solitary Nucleus | 1999 |
Group I metabotropic glutamate receptors mediate an inward current in rat substantia nigra dopamine neurons that is independent from calcium mobilization.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium; Chromones; Cycloleucine; Egtazic Acid; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Microscopy, Fluorescence; Neurons; Patch-Clamp Techniques; Rats; Receptors, Metabotropic Glutamate; Resorcinols; Substantia Nigra; Tetrodotoxin; Thapsigargin | 1999 |
The retention deficit induced by (RS)-alpha-methyl-4-carboxyphenylglycine in a lever-press learning task is blocked by selective agonists of either group I or group II metabotropic glutamate receptors.
Topics: Animals; Benzoates; Bridged Bicyclo Compounds; Cycloleucine; Dose-Response Relationship, Drug; Eating; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Learning; Male; Memory Disorders; Mice; Mice, Inbred Strains; Neuroprotective Agents; Protein Isoforms; Receptors, Metabotropic Glutamate; Resorcinols; Retention, Psychology; Time Factors | 1999 |
1-Aminoindan-1,5-dicarboxylic acid and (S)-(+)-2-(3'-carboxybicyclo[1.1.1] pentyl)-glycine, two mGlu1 receptor-preferring antagonists, reduce neuronal death in in vitro and in vivo models of cerebral ischaemia.
Topics: Animals; Animals, Newborn; Astrocytes; Benzoates; Bridged Bicyclo Compounds; Cell Death; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Gerbillinae; Glycine; Indans; Ischemic Attack, Transient; Mice; Neuroprotective Agents; Neurotoxins; Organ Culture Techniques; Pyramidal Cells; Quinoxalines; Receptors, Metabotropic Glutamate; Resorcinols | 1999 |
Functional group I metabotropic glutamate receptors in submucous plexus of guinea-pig ileum.
Topics: Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Guinea Pigs; Ileum; Male; Membrane Potentials; Quisqualic Acid; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Submucous Plexus | 1999 |
Presynaptic group 1 metabotropic glutamate receptors may contribute to the expression of long-term potentiation in the hippocampal CA1 region.
Topics: Animals; Azetidinecarboxylic Acid; Calcium; Cycloleucine; Dicarboxylic Acids; Diglycerides; Electric Stimulation; Electroencephalography; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Glycine; Hippocampus; Long-Term Potentiation; Male; Neuroprotective Agents; Neurotransmitter Uptake Inhibitors; Presynaptic Terminals; Pyrrolidines; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols; Synaptosomes | 1999 |
An antidepressant-induced decrease in the responsiveness of hippocampal neurons to group I metabotropic glutamate receptor activation.
Topics: Animals; Antidepressive Agents; Glycine; Hippocampus; Imipramine; Male; Membrane Potentials; Neurons; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols | 1999 |
[The ameliorating effects of a novel NC-1900 on impairments of learning/memory caused by glutamic acid].
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Arginine Vasopressin; Avoidance Learning; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Kainic Acid; Learning Disabilities; Male; Memory Disorders; Mice; Mice, Inbred Strains; N-Methylaspartate; Neuromuscular Depolarizing Agents; Oligopeptides; Pyrrolidonecarboxylic Acid; Rats; Rats, Sprague-Dawley; Resorcinols | 1999 |
Neuroprotective action of group I metabotropic glutamate receptor agonists against oxygen-glucose deprivation-induced neuronal death.
Topics: Animals; Cell Death; Cell Hypoxia; Cells, Cultured; Cerebellum; Cycloleucine; Electrophoresis, Agar Gel; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glucose; Glycine; In Situ Nick-End Labeling; Indans; Indoles; Maleimides; Neurons; Neuroprotective Agents; Protein Kinase C; Rats; Receptors, Metabotropic Glutamate; Resorcinols | 2000 |
Evaluation of the activity of a novel metabotropic glutamate receptor antagonist (+/-)-2-amino-2-(3-cis and trans-carboxycyclobutyl-3-(9-thioxanthyl)propionic acid) in the in vitro neonatal spinal cord and in an in vivo pain model.
Topics: Acetic Acid; Animals; Animals, Newborn; Cycloleucine; Electrophysiology; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Mice; Motor Neurons; Neuroprotective Agents; Nociceptors; Pain; Propionates; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols; Spinal Cord; Spinal Nerve Roots; Stereoisomerism | 2000 |
Behavioural evidence supporting a differential role for group I and II metabotropic glutamate receptors in spinal nociceptive transmission.
Topics: Amino Acids, Dicarboxylic; Animals; Behavior, Animal; Chronic Disease; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamates; Glycine; Indans; Injections, Spinal; Nociceptors; Pain Threshold; Physical Stimulation; Receptors, Metabotropic Glutamate; Resorcinols; Sheep; Spinal Cord; Synaptic Transmission | 2000 |
GABAergic mIPSCs in rat cerebellar Purkinje cells are modulated by TrkB and mGluR1-mediated stimulation of Src.
Topics: Animals; Bicuculline; Brain-Derived Neurotrophic Factor; Enzyme Inhibitors; Evoked Potentials; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Neural Inhibition; Oligopeptides; Organ Culture Techniques; Phenols; Purkinje Cells; Rats; Receptor, trkB; Receptors, GABA-A; Receptors, Metabotropic Glutamate; Resorcinols; Staurosporine; Synapses; Vanadates | 2000 |
Expression of functional mGlu5 metabotropic glutamate receptors in human melanocytes.
Topics: Amino Acid Sequence; Animals; Cell Death; Cells, Cultured; Cerebral Cortex; DNA; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Glycine; Humans; Immunohistochemistry; Infant, Newborn; Male; Melanocytes; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Phosphatidylinositol Phosphates; Pigmentation Disorders; Quisqualic Acid; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Skin; Sodium Glutamate; Tissue Extracts | 2000 |
Group I mGluR activation turns on a voltage-gated inward current in hippocampal pyramidal cells.
Topics: Animals; Calcium; Calcium Channel Blockers; Enzyme Inhibitors; Glycine; Guinea Pigs; Hippocampus; In Vitro Techniques; Ion Channels; Manganese; Membrane Potentials; Nimodipine; Patch-Clamp Techniques; Potassium; Pyramidal Cells; Receptors, Metabotropic Glutamate; Resorcinols; Sodium | 2000 |
Protein phosphatase 2B inhibitors mimic the action of arachidonic acid and prolong the facilitation of glutamate release by group I mGlu receptors.
Topics: 4-Aminopyridine; Animals; Arachidonic Acid; Calcineurin; Calcineurin Inhibitors; Calcium; Cyclosporine; Diglycerides; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Male; Membrane Potentials; Protein Phosphatase 1; Pyrethrins; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols; Synaptosomes; Time Factors | 2000 |
Metabotropic glutamate autoreceptors of the mGlu(5) subtype positively modulate neuronal glutamate release in the rat forebrain in vitro.
Topics: Animals; Aspartic Acid; Autoreceptors; Benzoates; Calcium; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; In Vitro Techniques; Indans; Male; Neurons; Phenylacetates; Prosencephalon; Quisqualic Acid; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Tetrodotoxin; Tritium | 2000 |
Anticonvulsant activity of two metabotropic glutamate group I antagonists selective for the mGlu5 receptor: 2-methyl-6-(phenylethynyl)-pyridine (MPEP), and (E)-6-methyl-2-styryl-pyridine (SIB 1893).
Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Female; Glycine; Injections, Intraperitoneal; Injections, Intraventricular; Male; Mice; Mice, Inbred DBA; Pyridines; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Seizures; Sound; Time Factors | 2000 |
Elevation of intradendritic sodium concentration mediated by synaptic activation of metabotropic glutamate receptors in cerebellar Purkinje cells.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dendrites; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Glycine; Image Processing, Computer-Assisted; Membrane Potentials; Mice; Mice, Inbred Strains; Microscopy, Fluorescence; Patch-Clamp Techniques; Picrotoxin; Purkinje Cells; Quinoxalines; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols; Sodium; Synapses; Synaptic Transmission; Tetrodotoxin | 2000 |
Motor stimulation following bilateral injection of the group-I metabotropic glutamate receptor agonist into the dorsal striatum of rats: evidence against dependence on ionotropic glutamate receptors.
Topics: Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Kainic Acid; Male; Microinjections; Motor Activity; N-Methylaspartate; Neostriatum; Neurons; Piperazines; Quinoxalines; Rats; Rats, Wistar; Receptors, Glutamate; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Resorcinols; Stimulation, Chemical | 2000 |
Behavioural activity of (S)-3,5-DHPG, a selective agonist of group I metabotropic glutamate receptors.
Topics: Animals; Apomorphine; Avoidance Learning; Behavior, Animal; Cycloleucine; Exploratory Behavior; Glycine; Long-Term Potentiation; Male; Motor Activity; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols | 2000 |
Protein phosphatase 1 and 2A inhibitors prolong the switch in the control of glutamate release by group I metabotropic glutamate receptors: characterization of the inhibitory pathway.
Topics: 4-Aminopyridine; Animals; Brain Chemistry; Calcium Channels, N-Type; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; GTP-Binding Proteins; Male; Pertussis Toxin; Phorbol 12,13-Dibutyrate; Phosphoprotein Phosphatases; Potassium; Potassium Channel Blockers; Protein Kinase C; Protein Phosphatase 1; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols; Signal Transduction; Synaptosomes; Virulence Factors, Bordetella | 2000 |
N-methyl-D-aspartate but not glutamate induces the release of hydroxyl radicals in the neonatal rat: modulation by group I metabotropic glutamate receptors.
Topics: Animals; Animals, Newborn; Corpus Striatum; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Hydroxybenzoates; Hydroxyl Radical; Hypoxia-Ischemia, Brain; Ibotenic Acid; Indans; Microdialysis; N-Methylaspartate; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Resorcinols | 2000 |
Age-related decline in the functional response of striatal group I mGlu receptors.
Topics: Aging; Animals; Dopamine; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glycine; Hydrolysis; Male; Microdialysis; N-Methylaspartate; Neostriatum; Neurons; Phosphatidylinositols; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols | 2000 |
Developmental regulation of hippocampal excitatory synaptic transmission by metabotropic glutamate receptors.
Topics: Animals; Cyclopropanes; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glycine; Hippocampus; Propionates; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Resorcinols; Synaptic Transmission | 2000 |
Cell-type specificity of mGluR activation in striatal neuronal subtypes.
Topics: Animals; Corpus Striatum; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Glycine; Male; Neurons; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols | 2000 |
Selective activation of group I metabotropic glutamate receptors upregulates preprodynorphin, substance P, and preproenkephalin mRNA expression in rat dorsal striatum.
Topics: Animals; Behavior, Animal; Dose-Response Relationship, Drug; Dynorphins; Enkephalins; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Male; Neostriatum; Neurons; Nucleus Accumbens; Protein Precursors; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols; RNA, Messenger; Substance P; Time Factors | 2001 |
Role of Ca2+ stores in metabotropic L-glutamate receptor-mediated supralinear Ca2+ signaling in rat hippocampal neurons.
Topics: Action Potentials; Animals; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Signaling; Cells, Cultured; Contraindications; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Extracellular Space; Glycine; Hippocampus; N-Methylaspartate; Neuroglia; Neurons; Patch-Clamp Techniques; Potassium; Rats; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Resorcinols | 2000 |
Sustained L-type calcium currents in dissociated deep dorsal horn neurons of the rat: characteristics and modulation.
Topics: Animals; Baclofen; Barium; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cycloleucine; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; GABA Agonists; Glycine; In Vitro Techniques; Male; Membrane Potentials; Nifedipine; Patch-Clamp Techniques; Posterior Horn Cells; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols | 2001 |
Functional coexpression of excitatory mGluR1 and mGluR5 on striatal cholinergic interneurons.
Topics: Animals; Cholinergic Fibers; Corpus Striatum; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Interneurons; Male; Membrane Potentials; Phenylacetates; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols | 2001 |
Modulation of the neuronal dopamine transporter activity by the metabotropic glutamate receptor mGluR5 in rat striatal synaptosomes through phosphorylation mediated processes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Carrier Proteins; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glycine; Indoles; Isoquinolines; Kinetics; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Neurons; Phosphorylation; Pyridines; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Staurosporine; Sulfonamides; Synaptosomes; Tetradecanoylphorbol Acetate | 2001 |
Group I metabotropic glutamate receptors are expressed in the chicken retina and by cultured retinal amacrine cells.
Topics: Amino Acid Sequence; Animals; Antibody Specificity; Blotting, Western; Calcium Signaling; Cells, Cultured; Chickens; Cycloleucine; Excitatory Amino Acid Agonists; Eye Proteins; Fluorescent Antibody Technique, Indirect; gamma-Aminobutyric Acid; Glycine; Molecular Sequence Data; Molecular Weight; Rats; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Retina | 2001 |
Seizure-like activity in the disinhibited CA1 minislice of adult guinea-pigs.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Age Factors; Animals; Bicuculline; Epilepsy; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Glycine; Guinea Pigs; Hippocampus; Neural Inhibition; Neurons, Afferent; Organ Culture Techniques; Picrotoxin; Pyridazines; Receptors, AMPA; Receptors, GABA-A; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Resorcinols | 2001 |
An activity-dependent switch from facilitation to inhibition in the control of excitotoxicity by group I metabotropic glutamate receptors.
Topics: Animals; Cells, Cultured; Cerebral Cortex; Enzyme Activation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Mice; N-Methylaspartate; Nerve Degeneration; Neural Inhibition; Neuroprotective Agents; Neurotoxins; Protein Kinase C; Quisqualic Acid; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Time Factors | 2001 |
Metabotropic glutamate receptor subtypes 1 and 5 are activators of extracellular signal-regulated kinase signaling required for inflammatory pain in mice.
Topics: Alternative Splicing; Animals; Behavior, Animal; Enzyme Activation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Formaldehyde; Glycine; Hindlimb; Immunohistochemistry; Inflammation; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neuronal Plasticity; Pain Measurement; Posterior Horn Cells; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Signal Transduction | 2001 |
Group I mGluRs coupled to G proteins are regulated by tyrosine kinase in dopamine neurons of the rat midbrain.
Topics: Animals; Dopamine; Enzyme Activation; Enzyme Inhibitors; Estrenes; Excitatory Amino Acid Antagonists; Female; Genistein; Glycine; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Male; Membrane Potentials; Mesencephalon; Neurons; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Protein Kinase C; Protein-Tyrosine Kinases; Pyrrolidinones; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols; Thionucleotides; Type C Phospholipases; Tyrphostins | 2001 |
Stimulation of Na-K-2Cl cotransporter in neurons by activation of Non-NMDA ionotropic receptor and group-I mGluRs.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Calcium; Carrier Proteins; Cells, Cultured; Chromones; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Fetus; Glycine; Neurons; Neuroprotective Agents; Phosphorylation; Potassium; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Resorcinols; Rubidium Radioisotopes; Sodium-Potassium-Chloride Symporters | 2001 |
Chemical induction of mGluR5- and protein synthesis--dependent long-term depression in hippocampal area CA1.
Topics: 2-Amino-5-phosphonovalerate; Animals; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; Hippocampus; Long-Term Potentiation; Mice; Mice, Knockout; Neural Inhibition; Organ Culture Techniques; Rats; Rats, Long-Evans; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; RNA, Messenger; Stimulation, Chemical | 2001 |
Glutamate inhibition of NMDA-induced hydroxyl radical release: an ontogenic study in rat.
Topics: Aging; Animals; Animals, Newborn; Brain; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Hydroxyl Radical; Microdialysis; N-Methylaspartate; Neurons; Neurotoxins; Oxidative Stress; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Resorcinols; Salicylates | 2001 |
Role of metabotropic glutamate receptors in vasopressin and oxytocin release.
Topics: Aminobutyrates; Animals; Cycloleucine; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Hypothalamo-Hypophyseal System; In Vitro Techniques; Indans; Male; Neurons; Neuroprotective Agents; Osmolar Concentration; Oxytocin; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols; Vasopressins | 2001 |
Endogenous sulphur-containing amino acids: potent agonists at presynaptic metabotropic glutamate autoreceptors in the rat central nervous system.
Topics: Amino Acids, Sulfur; Animals; Aspartic Acid; Autoreceptors; Calcium; Central Nervous System; Cysteic Acid; Cysteine; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glycine; Male; Neurotransmitter Agents; Presynaptic Terminals; Prosencephalon; Pyridines; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols; Tetrodotoxin; Tritium | 2001 |
Anticonvulsant activity of a mGlu(4alpha) receptor selective agonist, (1S,3R,4S)-1-aminocyclopentane-1,2,4-tricarboxylic acid.
Topics: Acoustic Stimulation; Alanine; Aminobutyrates; Animals; Anticonvulsants; Behavior, Animal; Cyclopentanes; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glycine; Injections, Intraventricular; Male; Mice; Mice, Inbred DBA; Phosphoserine; Psychomotor Performance; Rats; Receptors, Metabotropic Glutamate; Resorcinols; Seizures; Tricarboxylic Acids | 2001 |
Metabotropic glutamate receptors 1 and 5 differentially regulate CA1 pyramidal cell function.
Topics: Animals; Benzoates; Calcium; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Fluorescent Dyes; Glycine; Hippocampus; In Vitro Techniques; Interneurons; Neural Inhibition; Patch-Clamp Techniques; Potassium Channels; Pyramidal Cells; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Resorcinols; Synaptic Transmission | 2001 |
Group I metabotropic glutamate receptors elicit epileptiform discharges in the hippocampus through PLCbeta1 signaling.
Topics: Animals; Biological Clocks; Cell Membrane; Crosses, Genetic; Enzyme Inhibitors; Epilepsy; Excitatory Amino Acid Agonists; Glycine; Hippocampus; Homozygote; In Vitro Techniques; Isoenzymes; Mice; Mice, Inbred Strains; Mice, Knockout; Nerve Net; Neurons; Patch-Clamp Techniques; Periodicity; Phospholipase C beta; Potassium; Receptors, Metabotropic Glutamate; Resorcinols; Sensory Thresholds; Signal Transduction; Type C Phospholipases | 2001 |
Changes in rat serum corticosterone after treatment with metabotropic glutamate receptor agonists or antagonists.
Topics: Adrenalectomy; Adrenocorticotropic Hormone; Amino Acids; Animals; Benzoates; Bridged Bicyclo Compounds; Corticosterone; Cycloleucine; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Male; Neuroprotective Agents; Paraventricular Hypothalamic Nucleus; Phenylacetates; Propionates; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Xanthenes | 2001 |
A polyketide synthase in glycopeptide biosynthesis: the biosynthesis of the non-proteinogenic amino acid (S)-3,5-dihydroxyphenylglycine.
Topics: Amino Acids; Bacterial Proteins; Chromatography, High Pressure Liquid; Coenzyme A Ligases; Excitatory Amino Acid Antagonists; Gene Deletion; Glycine; Glycopeptides; Models, Chemical; Models, Genetic; Molecular Sequence Data; Multienzyme Complexes; Mutagenesis, Site-Directed; Plasmids; Resorcinols; Sequence Analysis, DNA; Streptomyces; Vancomycin | 2001 |
Metabotropic glutamate 1alpha receptors on peripheral primary afferent fibers: their role in nociception.
Topics: Animals; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Ganglia, Spinal; Glycine; Immunohistochemistry; Indans; Inflammation; Male; Microscopy, Electron; Nerve Fibers; Neurons, Afferent; Nociceptors; Pain; Pain Measurement; Physical Stimulation; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols; Signal Transduction; Skin; Thermosensing | 2001 |
Characterization of the mGluR(1)-mediated electrical and calcium signaling in Purkinje cells of mouse cerebellar slices.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Signaling; Calcium-Transporting ATPases; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; Imidazoles; Indoles; Mice; Mice, Inbred ICR; Nimodipine; Organ Culture Techniques; Patch-Clamp Techniques; Purkinje Cells; Receptors, Metabotropic Glutamate; Resorcinols; Sarcoplasmic Reticulum; Sodium; Thapsigargin | 2001 |
Glutamate release inhibiting properties of the novel mGlu(5) receptor antagonist 2-methyl-6-(phenylethynyl)-pyridine (MPEP): complementary in vitro and in vivo evidence.
Topics: Animals; Brain Chemistry; Electric Stimulation; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; In Vitro Techniques; Male; Microdialysis; Pyridines; Rats; Rats, Wistar; Receptors, Kainic Acid; Resorcinols | 2001 |
Glutamate receptor stimulation induces a persistent rhythmicity of the GABAergic inputs to rat midbrain dopaminergic neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Benzoates; Dopamine; Electrophysiology; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Gap Junctions; Glycine; Membrane Potentials; Neural Pathways; Neurons; Periodicity; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Resorcinols; Substantia Nigra | 2001 |
Alpha 1-adrenergic modulation of metabotropic glutamate receptor-induced calcium oscillations and glutamate release in astrocytes.
Topics: Animals; Astrocytes; Calcium; Calcium Signaling; Cells, Cultured; Chromatography, High Pressure Liquid; Glutamic Acid; Glycine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, Metabotropic Glutamate; Resorcinols | 2001 |
Metabotropic glutamate receptor 5 mediates the potentiation of N-methyl-D-aspartate responses in medium spiny striatal neurons.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Action Potentials; Animals; Anticonvulsants; Benzoates; Cyclopropanes; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Mice; Mice, Knockout; Muscarine; Muscarinic Agonists; N-Methylaspartate; Neostriatum; Neurons; Phenylacetates; Pyridines; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Resorcinols; Synaptic Transmission | 2001 |
Effect of the group I metabotropic glutamate agonist DHPG on the visual cortex.
Topics: Action Potentials; Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cats; Drug Synergism; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; N-Methylaspartate; Organ Culture Techniques; Phenylacetates; Presynaptic Terminals; Rats; Receptors, Metabotropic Glutamate; Resorcinols; Visual Cortex | 2001 |
Metabotropic glutamate receptor activation causes a rapid redistribution of AMPA receptors.
Topics: Animals; Cells, Cultured; Depsipeptides; Dynamins; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Glycine; GTP Phosphohydrolases; Hippocampus; In Vitro Techniques; Nerve Tissue Proteins; Neural Inhibition; Neurons; Patch-Clamp Techniques; Peptides; Peptides, Cyclic; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Metabotropic Glutamate; Resorcinols; Synaptic Transmission | 2001 |
Group I metabotropic glutamate receptors limit AMPA receptor-mediated oligodendrocyte progenitor cell death.
Topics: Animals; Anti-Anxiety Agents; Benzoates; Benzodiazepines; Cell Death; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Kainic Acid; Oligodendroglia; Rats; Receptors, AMPA; Receptors, Metabotropic Glutamate; Resorcinols; Stem Cells | 2001 |
Group I metabotropic glutamate receptors control phosphorylation of CREB, Elk-1 and ERK via a CaMKII-dependent pathway in rat striatum.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Corpus Striatum; Cyclic AMP Response Element-Binding Protein; DNA-Binding Proteins; Enzyme Inhibitors; ets-Domain Protein Elk-1; Excitatory Amino Acid Agonists; Glycine; Immunohistochemistry; Male; Microinjections; Mitogen-Activated Protein Kinases; Phosphorylation; Proto-Oncogene Proteins; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols; Signal Transduction; Transcription Factors | 2001 |
Internalization of ionotropic glutamate receptors in response to mGluR activation.
Topics: Amino Acids; Animals; Cells, Cultured; Cycloheximide; Dendrites; Electrophysiology; Endocytosis; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; Hippocampus; Immunohistochemistry; In Vitro Techniques; Methoxyhydroxyphenylglycol; Neurons; Protein Synthesis Inhibitors; Rats; Rats, Long-Evans; Receptors, AMPA; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Resorcinols; Synapses; Synapsins; Synaptic Transmission; Xanthenes | 2001 |
Repeated cocaine administration attenuates group I metabotropic glutamate receptor-mediated glutamate release and behavioral activation: a potential role for Homer.
Topics: Animals; Brain Chemistry; Calcium Channel Blockers; Carrier Proteins; Cocaine; Drug Administration Schedule; Drug Tolerance; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Space; Glutamic Acid; Glycine; Homer Scaffolding Proteins; Male; Microdialysis; Motor Activity; Neuropeptides; Nucleus Accumbens; Rats; Rats, Inbred Strains; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, AMPA; Receptors, Metabotropic Glutamate; Resorcinols; Tetrodotoxin | 2001 |
Gap junctions between interneuron dendrites can enhance synchrony of gamma oscillations in distributed networks.
Topics: Animals; Biological Clocks; Carbenoxolone; Computer Simulation; Dendrites; Electric Stimulation; Gap Junctions; Glutamic Acid; Glycine; Hippocampus; In Vitro Techniques; Interneurons; Male; Models, Neurological; Nerve Net; Neural Networks, Computer; Potassium; Rats; Rats, Wistar; Receptors, GABA-A; Resorcinols; Sensory Thresholds; Stimulation, Chemical | 2001 |
A characterisation of long-term depression induced by metabotropic glutamate receptor activation in the rat hippocampus in vitro.
Topics: Animals; Cells, Cultured; Dendrites; Electrophysiology; Excitatory Postsynaptic Potentials; Glycine; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Neurons; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols | 2001 |
Glycopeptide antibiotic biosynthesis: enzymatic assembly of the dedicated amino acid monomer (S)-3,5-dihydroxyphenylglycine.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Base Sequence; Coenzyme A Ligases; DNA Primers; Glycine; Glycopeptides; Kinetics; Oxidation-Reduction; Resorcinols | 2001 |
Differential roles for mGluR1 and mGluR5 in the persistent prolongation of epileptiform bursts.
Topics: Animals; Benzoates; Convulsants; Dose-Response Relationship, Drug; Epilepsy; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; Glycine; Guinea Pigs; Hippocampus; In Vitro Techniques; Membrane Potentials; Picrotoxin; Pyridines; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Time Factors | 2002 |
Activation of group I mGluRs elicits different responses in murine CA1 and CA3 pyramidal cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; In Vitro Techniques; Membrane Potentials; Mice; Mice, Knockout; Neural Conduction; Patch-Clamp Techniques; Pyramidal Cells; Receptors, Metabotropic Glutamate; Resorcinols; Tetrodotoxin | 2002 |
Extracellular calcium controls the dynamic range of neuronal metabotropic glutamate receptor responses.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Signaling; Cells, Cultured; Chelating Agents; Dioxolanes; Dose-Response Relationship, Drug; Egtazic Acid; Excitatory Amino Acid Agonists; Extracellular Space; Female; Fetus; Glycine; Imidazoles; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Knockout; Purines; Purkinje Cells; Receptors, Metabotropic Glutamate; Resorcinols; Synapses; Synaptic Transmission; Up-Regulation | 2002 |
Group I mGluRs increase excitability of hippocampal CA1 pyramidal neurons by a PLC-independent mechanism.
Topics: Animals; Electrophysiology; Excitatory Amino Acid Agonists; Glycine; Hippocampus; Hydrolysis; Male; Phosphatidylinositols; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols; Signal Transduction; Type C Phospholipases | 2002 |
Metabotropic glutamate receptor 1-induced upregulation of NMDA receptor current: mediation through the Pyk2/Src-family kinase pathway in cortical neurons.
Topics: Animals; Cell Line; Cells, Cultured; Cerebral Cortex; Electric Conductivity; Excitatory Amino Acid Agonists; Focal Adhesion Kinase 2; Glycine; Humans; Mice; Neurons; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fyn; Proto-Oncogene Proteins pp60(c-src); Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Resorcinols; Signal Transduction; src-Family Kinases; Up-Regulation | 2002 |
Activation of spinal group I metabotropic glutamate receptors in rats evokes local glutamate release and spontaneous nociceptive behaviors: effects of 2-methyl-6-(phenylethynyl)-pyridine pretreatment.
Topics: Animals; Behavior, Animal; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Space; Glutamic Acid; Glycine; Male; Microdialysis; Pain; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols; Spinal Cord; Time Factors | 2002 |
D1 and D2 dopamine receptors contribute to the locomotor response induced by Group II mGluRs activation in the rat nucleus accumbens.
Topics: Amino Acids, Dicarboxylic; Animals; Benzazepines; Dopamine Antagonists; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Male; Microinjections; Motor Activity; Nucleus Accumbens; Raclopride; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Metabotropic Glutamate; Resorcinols; Stimulation, Chemical | 2002 |
Determinants of ictal epileptiform patterns in the hippocampal slice.
Topics: Animals; Calcium; Calcium Channels, L-Type; Dantrolene; Electrophysiology; Enzyme Inhibitors; Epilepsy; Excitatory Amino Acid Agonists; Glycine; Hippocampus; In Vitro Techniques; Male; Muscarinic Agonists; Neural Inhibition; Pilocarpine; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Glutamate; Resorcinols; Thapsigargin | 2002 |
Modulation of presynaptic calcium transients by metabotropic glutamate receptor activation: a differential role in acute depression of synaptic transmission and long-term depression.
Topics: Animals; Calcium; Calcium Signaling; Electric Stimulation; Excitatory Postsynaptic Potentials; Fluorescent Dyes; Fura-2; Glycine; Hippocampus; In Vitro Techniques; Microelectrodes; Microinjections; Neural Inhibition; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Synaptic Transmission; Time | 2002 |
Tyrosine dephosphorylation underlies DHPG-induced LTD.
Topics: Animals; Female; Glycine; Hippocampus; In Vitro Techniques; Long-Term Synaptic Depression; Phosphorylation; Protein Tyrosine Phosphatases; Rats; Rats, Wistar; Resorcinols; Synaptic Transmission; Tyrosine | 2002 |
Mechanism of regulation of casein kinase I activity by group I metabotropic glutamate receptors.
Topics: Animals; Calcineurin; Casein Kinases; Chelating Agents; Cyclin-Dependent Kinase 5; Cyclin-Dependent Kinases; Cyclosporine; Dopamine and cAMP-Regulated Phosphoprotein 32; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Estrenes; Excitatory Amino Acid Agonists; Glycine; In Vitro Techniques; Male; Mice; Neostriatum; Nerve Tissue Proteins; Peptide Mapping; Phosphoproteins; Phosphorylation; Protein Kinases; Pyrrolidinones; Receptors, Metabotropic Glutamate; Resorcinols; Serine; Signal Transduction; Threonine; Tumor Cells, Cultured; Type C Phospholipases | 2002 |
Inhibition of group I metabotropic glutamate receptor responses in vivo in rats by a new generation of carboxyphenylglycine-like amino acid antagonists.
Topics: Alanine; Animals; Benzoates; Cerebellum; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Inhibitory Concentration 50; Mice; Propionates; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols; Seizures; Structure-Activity Relationship; Thiophenes; Xanthenes | 2002 |
Different metabotropic glutamate receptors play opposite roles in synaptic plasticity of the rat medial vestibular nuclei.
Topics: Amino Acids; Animals; Chromones; Excitatory Amino Acid Antagonists; Glycine; Membrane Potentials; Neuronal Plasticity; Organ Culture Techniques; Phenylacetates; Pyridines; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Vestibular Nuclei; Xanthenes | 2002 |
Biosynthesis of the vancomycin group of antibiotics: characterisation of a type III polyketide synthase in the pathway to (S)-3,5-dihydroxyphenylglycine.
Topics: Actinomycetales; Chromatography, Gas; Gene Expression Regulation, Bacterial; Genes, Bacterial; Glycine; Mass Spectrometry; Molecular Structure; Multienzyme Complexes; Polymerase Chain Reaction; Resorcinols; Sequence Homology, Amino Acid; Vancomycin | 2001 |
Characterisation of a hydroxymandelate oxidase involved in the biosynthesis of two unusual amino acids occurring in the vancomycin group of antibiotics.
Topics: Alcohol Oxidoreductases; Amino Acids; Bacterial Proteins; Chromatography, Gas; Gene Expression Regulation, Bacterial; Glycine; Membrane Proteins; Molecular Structure; Oxidoreductases; Resorcinols; Spectrophotometry; Vancomycin | 2001 |
Differential regulation of metabotropic glutamate receptor 5-mediated phosphoinositide hydrolysis and extracellular signal-regulated kinase responses by protein kinase C in cultured astrocytes.
Topics: Animals; Astrocytes; Calcium Signaling; Cells, Cultured; Enzyme Activation; Enzyme Activators; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Glycine; Hydrolysis; Isoenzymes; Mitogen-Activated Protein Kinase 1; Phosphatidylinositols; Phospholipase C beta; Phosphorylation; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Signal Transduction; Type C Phospholipases | 2002 |
Group I metabotropic glutamate receptor-mediated enhancement of dopamine cell burst firing in rat ventral tegmental area in vitro.
Topics: Action Potentials; Animals; Apamin; Benzoates; Biological Clocks; Cycloleucine; Dopamine; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Male; Membrane Potentials; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Rats; Receptors, Metabotropic Glutamate; Resorcinols; Ventral Tegmental Area | 2002 |
The group I metabotropic glutamate receptor agonist (S)-3,5-dihydroxyphenylglycine induces a novel form of depotentiation in the CA1 region of the hippocampus.
Topics: Animals; Anti-Bacterial Agents; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Glycine; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; Neural Inhibition; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, AMPA; Receptors, Metabotropic Glutamate; Resorcinols; Sirolimus; Synaptic Transmission | 2002 |
Distinct functional roles of the metabotropic glutamate receptors 1 and 5 in the rat globus pallidus.
Topics: Animals; Cells, Cultured; Central Nervous System; Electric Conductivity; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Globus Pallidus; Glycine; Neurons; Parkinson Disease; Patch-Clamp Techniques; Phenotype; Protein Kinase C; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols | 2003 |
Group I metabotropic glutamate receptors modulate glutamate and gamma-aminobutyric acid release in the periaqueductal grey of rats.
Topics: Animals; Chromones; Dendrites; Excitatory Amino Acid Agonists; gamma-Aminobutyric Acid; Glutamates; Glycine; Male; Microdialysis; Microscopy, Electron; Periaqueductal Gray; Phenylacetates; Piperazines; Pyridines; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Resorcinols; Tetrodotoxin | 2003 |
Long-term potentiation of mGluR1 activity by depolarization-induced Homer1a in mouse cerebellar Purkinje neurons.
Topics: Animals; Calcium; Carrier Proteins; Cells, Cultured; Excitatory Amino Acid Agonists; Glycine; Homer Scaffolding Proteins; Humans; Immunohistochemistry; Kidney; Long-Term Potentiation; Membrane Potentials; Mice; Mice, Inbred ICR; Mitogen-Activated Protein Kinases; Neuronal Plasticity; Neuropeptides; Patch-Clamp Techniques; Purkinje Cells; Receptors, Metabotropic Glutamate; Resorcinols; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction | 2003 |
Group I mGlu receptors regulate the expression of the neuronal calcium sensor protein VILIP-1 in vitro and in vivo: implications for mGlu receptor-dependent hippocampal plasticity?
Topics: Animals; Benzoates; Calcium-Binding Proteins; Cells, Cultured; Dentate Gyrus; Dioxolanes; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; In Vitro Techniques; Male; Nerve Tissue Proteins; Neurocalcin; Neuronal Plasticity; Purines; Pyramidal Cells; Rats; Rats, Wistar; Receptors, Calcium-Sensing; Receptors, Metabotropic Glutamate; Resorcinols; RNA, Messenger; Synaptic Transmission; Up-Regulation | 2003 |
mGluR1, but not mGluR5, mediates depolarization of spinal cord neurons by blocking a leak current.
Topics: Animals; Excitatory Amino Acid Agonists; Glycine; In Vitro Techniques; Lampreys; Membrane Potentials; Neuromuscular Depolarizing Agents; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Spinal Cord | 2003 |
Characterisation of the actions of group I metabotropic glutamate receptor subtype selective ligands on excitatory amino acid release and sodium-dependent re-uptake in rat cerebrocortical minislices.
Topics: Animals; Binding, Competitive; Biological Transport; Cerebral Cortex; D-Aspartic Acid; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Glycine; In Vitro Techniques; Ligands; Male; Potassium; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Sodium; Tritium | 2003 |
Nicotine recruits a local glutamatergic circuit to excite septohippocampal GABAergic neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aconitine; Acyclovir; Animals; Animals, Newborn; Atropine; Bicuculline; Bungarotoxins; Carrier Proteins; Cell Count; Choline; Chromones; Cycloleucine; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Interactions; Electric Conductivity; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Hippocampus; Immunohistochemistry; In Vitro Techniques; Male; Membrane Potentials; Membrane Transport Proteins; Microscopy, Electron; Muscarine; Muscarinic Agonists; Muscarinic Antagonists; Neurons; Neuroprotective Agents; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Parvalbumins; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Resorcinols; Septum of Brain; Synapses; Tetrodotoxin; Tubocurarine; Valine; Vesicular Glutamate Transport Protein 2; Vesicular Transport Proteins | 2003 |
Neuroprotection against NMDA excitotoxicity by group I metabotropic glutamate receptors is associated with reduction of NMDA stimulated currents.
Topics: Animals; Cells, Cultured; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; In Vitro Techniques; N-Methylaspartate; Neurons; Neurotoxins; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols | 2003 |
The fragile X mental retardation protein is required for type-I metabotropic glutamate receptor-dependent translation of PSD-95.
Topics: Animals; Base Sequence; Binding Sites; Conserved Sequence; Disks Large Homolog 4 Protein; Fragile X Mental Retardation Protein; Fragile X Syndrome; Glycine; Guanylate Kinases; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Tissue Proteins; Protein Biosynthesis; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols; RNA-Binding Proteins; RNA, Messenger; Sequence Homology, Nucleic Acid | 2003 |
Activation of the TRPC1 cation channel by metabotropic glutamate receptor mGluR1.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium; Calcium Channels; CHO Cells; Cricetinae; Culture Techniques; Excitatory Postsynaptic Potentials; Glycine; Humans; Ion Channel Gating; Precipitin Tests; Purkinje Cells; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Resorcinols; Synapses; Transfection; TRPC Cation Channels | 2003 |
Presynaptic group I metabotropic glutamate receptors modulate synaptic transmission in the rat superior colliculus via 4-AP sensitive K(+) channels.
Topics: 4-Aminopyridine; Action Potentials; Animals; Calcium Channel Blockers; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Glycine; In Vitro Techniques; Ion Channel Gating; Patch-Clamp Techniques; Potassium Channel Blockers; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, Presynaptic; Resorcinols; Superior Colliculi; Synaptic Transmission | 2003 |
Glutamate spillover in the striatum depresses dopaminergic transmission by activating group I metabotropic glutamate receptors.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Corpus Striatum; Dopamine; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Glycine; In Vitro Techniques; Ligands; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Symporters; Synaptic Transmission | 2003 |
Chronic hyperammonemia alters motor and neurochemical responses to activation of group I metabotropic glutamate receptors in the nucleus accumbens in rats in vivo.
Topics: Animals; Chromones; Chronic Disease; Dopamine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Fluid; Glutamic Acid; Glycine; Hepatic Encephalopathy; Hyperammonemia; Immunohistochemistry; Microdialysis; Microinjections; Motor Activity; Nucleus Accumbens; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols | 2003 |
Difference in mGluR5 interaction between positive allosteric modulators from two structural classes.
Topics: Animals; Benzamides; Binding Sites; CHO Cells; Cricetinae; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Humans; Hydrazines; Phthalimides; Rats; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Structure-Activity Relationship | 2003 |
Rap1-induced p38 mitogen-activated protein kinase activation facilitates AMPA receptor trafficking via the GDI.Rab5 complex. Potential role in (S)-3,5-dihydroxyphenylglycene-induced long term depression.
Topics: Animals; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Cell Membrane; Electrophysiology; Endocytosis; Glycine; GTP-Binding Protein beta Subunits; GTP-Binding Protein gamma Subunits; Guanine Nucleotide Dissociation Inhibitors; Hippocampus; Male; MAP Kinase Kinase 3; MAP Kinase Kinase 6; MAP Kinase Signaling System; Methoxyhydroxyphenylglycol; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Models, Biological; p38 Mitogen-Activated Protein Kinases; Protein Binding; Protein Structure, Tertiary; Protein Transport; Protein-Tyrosine Kinases; rab5 GTP-Binding Proteins; rap1 GTP-Binding Proteins; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Resorcinols; Signal Transduction; Synapses; Time Factors | 2004 |
Group I metabotropic glutamate receptors regulate the frequency-response function of hippocampal CA1 synapses for the induction of LTP and LTD.
Topics: Animals; Electric Stimulation; Excitatory Amino Acid Agonists; Glutamic Acid; Glycine; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Long-Term Synaptic Depression; Male; Neural Pathways; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols; Synapses; Synaptic Transmission | 2004 |
Group I metabotropic glutamate receptor activation produces a direct excitation of identified septohippocampal cholinergic neurons.
Topics: Animals; Carrier Proteins; Cholinergic Fibers; Dose-Response Relationship, Drug; Electrophysiology; Excitatory Amino Acid Agonists; Frontal Lobe; Glycine; Hippocampus; Immunologic Techniques; In Vitro Techniques; Male; Membrane Transport Proteins; Neurons; Osmolar Concentration; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Septum of Brain; Synapses; Tissue Distribution; Vesicular Glutamate Transport Protein 2; Vesicular Transport Proteins | 2004 |
The protein phosphatase 1/2A inhibitor okadaic acid increases CREB and Elk-1 phosphorylation and c-fos expression in the rat striatum in vivo.
Topics: Animals; Corpus Striatum; Cyclic AMP Response Element-Binding Protein; DNA-Binding Proteins; Enzyme Inhibitors; ets-Domain Protein Elk-1; Excitatory Amino Acid Agonists; Glycine; Male; Microinjections; Mitogen-Activated Protein Kinases; Neurons; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Protein Phosphatase 1; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Resorcinols; RNA, Messenger; Transcription Factors | 2004 |
Endoplasmic reticulum export site formation and function in dendrites.
Topics: Animals; Cell Membrane Permeability; Cells, Cultured; COP-Coated Vesicles; Dendrites; Endoplasmic Reticulum; Excitatory Amino Acid Agents; Glycine; Macromolecular Substances; Membrane Proteins; Monomeric GTP-Binding Proteins; Nuclear Pore Complex Proteins; Protein Transport; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Resorcinols; Saccharomyces cerevisiae Proteins | 2004 |
Mutasynthesis of glycopeptide antibiotics: variations of vancomycin's AB-ring amino acid 3,5-dihydroxyphenylglycine.
Topics: Actinobacteria; Anti-Bacterial Agents; Culture Media; Glycine; Glycopeptides; Molecular Conformation; Mutation; Resorcinols; Spectrometry, Mass, Electrospray Ionization; Vancomycin | 2004 |
Excitation of cerebellar interneurons by group I metabotropic glutamate receptors.
Topics: Action Potentials; Animals; Benzoates; Cerebellum; Glycine; In Vitro Techniques; Interneurons; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols | 2004 |
Extracellular signal-regulated protein kinase activation is required for metabotropic glutamate receptor-dependent long-term depression in hippocampal area CA1.
Topics: Animals; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Glycine; Hippocampus; In Vitro Techniques; Long-Term Synaptic Depression; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Rats; Rats, Long-Evans; Receptors, Metabotropic Glutamate; Resorcinols; Signal Transduction | 2004 |
Interactions between NMDA receptors and mGlu5 receptors expressed in HEK293 cells.
Topics: Animals; Arsenicals; Cell Line; Drug Synergism; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Gene Expression; Genistein; Glycine; Humans; N-Methylaspartate; Phosphorylation; Protein-Tyrosine Kinases; Rats; Receptor Cross-Talk; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Recombinant Fusion Proteins; Resorcinols; Staurosporine; Thapsigargin; Transfection; Tyrosine; Vanadates | 2004 |
Retroinhibition of presynaptic Ca2+ currents by endocannabinoids released via postsynaptic mGluR activation at a calyx synapse.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Benzoxazines; Brain Stem; Calcium Signaling; Cannabinoid Receptor Modulators; Endocannabinoids; Evoked Potentials, Auditory, Brain Stem; Glycine; Ion Transport; Morpholines; Naphthalenes; Nerve Endings; Patch-Clamp Techniques; Picrotoxin; Piperidines; Pyrazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptors, Metabotropic Glutamate; Receptors, Presynaptic; Resorcinols; Scopolamine; Synaptic Transmission; Xanthenes | 2004 |
Activation of the phosphoinositide 3-kinase-Akt-mammalian target of rapamycin signaling pathway is required for metabotropic glutamate receptor-dependent long-term depression.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Androstadienes; Animals; Benzoates; Chromones; Dendrites; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Glycine; Hippocampus; Long-Term Synaptic Depression; Male; Mice; Mice, Inbred C57BL; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinases; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyramidal Cells; Pyridines; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Signal Transduction; Sirolimus; Synaptosomes; Tacrolimus; TOR Serine-Threonine Kinases; Wortmannin | 2004 |
Altered agonist sensitivity and desensitization of neuronal mGluR1 responses in knock-in mice by a single amino acid substitution at the PKC phosphorylation site.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Chimera; Excitatory Amino Acid Agonists; Female; Glycine; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Molecular Sequence Data; Phosphorylation; Protein Kinase C; Receptors, Metabotropic Glutamate; Resorcinols | 2004 |
Activation of group I metabotropic glutamate receptors enhances efficacy of glutamatergic inputs to neonatal rat hypoglossal motoneurons in vitro.
Topics: Action Potentials; Animals; Animals, Newborn; Glutamic Acid; Glycine; Hypoglossal Nerve; In Vitro Techniques; Motor Neurons; Neural Pathways; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols | 2004 |
Chronic interleukin-6 exposure alters metabotropic glutamate receptor-activated calcium signalling in cerebellar Purkinje neurons.
Topics: Adenosine Triphosphatases; Animals; Brain Diseases; Calcium; Calcium Channel Blockers; Calcium Signaling; Cells, Cultured; Drug Administration Schedule; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Glycine; Interleukin-6; Intracellular Fluid; Membrane Potentials; Potassium; Purkinje Cells; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols; Ryanodine Receptor Calcium Release Channel; Up-Regulation | 2004 |
Fragile X mental retardation protein is necessary for neurotransmitter-activated protein translation at synapses.
Topics: Animals; Fragile X Mental Retardation Protein; Gene Deletion; Glycine; Methionine; Mice; Mice, Knockout; Microscopy, Electron; Nerve Tissue Proteins; Neurotransmitter Agents; Potassium; Protein Biosynthesis; Resorcinols; Ribosomes; RNA-Binding Proteins; Synapses | 2004 |
Effects of the group I metabotropic glutamate receptor agonist, DHPG, and injection stress on striatal cell signaling in food-restricted and ad libitum fed rats.
Topics: Animals; Cyclic AMP Response Element-Binding Protein; Excitatory Amino Acid Agonists; Extracellular Signal-Regulated MAP Kinases; Food Deprivation; Glycine; Injections, Intraventricular; Male; MAP Kinase Signaling System; Neostriatum; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols | 2004 |
Role of protein phosphatase 2A in mGluR5-regulated MEK/ERK phosphorylation in neurons.
Topics: Animals; Blotting, Western; Brain; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Glycine; Immunoprecipitation; MAP Kinase Kinase 1; Marine Toxins; Microscopy, Confocal; Microscopy, Fluorescence; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neurons; Okadaic Acid; Oxazoles; Peptides; Phenylacetates; Phosphoprotein Phosphatases; Phosphorylation; Protein Phosphatase 2; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Rats; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Serine; Signal Transduction; Threonine; Time Factors; Up-Regulation | 2005 |
Interleukin-1 beta down-regulates the expression of metabotropic glutamate receptor 5 in cultured human astrocytes.
Topics: Astrocytes; Cells, Cultured; Down-Regulation; Excitatory Amino Acid Agonists; Glycine; Humans; Hydrolysis; Inositol Phosphates; Interleukin-1; Receptor, Metabotropic Glutamate 5; Receptors, Interleukin-1; Receptors, Metabotropic Glutamate; Recombinant Proteins; Resorcinols | 2005 |
Behavioral and convulsant effects of the (S) enantiomer of the group I metabotropic glutamate receptor agonist 3,5-DHPG in mice.
Topics: Animals; Behavior, Animal; Behavioral Symptoms; Convulsants; Dose-Response Relationship, Drug; Drug Interactions; Electroencephalography; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Male; Mice; Mice, Inbred ICR; Regression Analysis; Resorcinols | 2005 |
Stimulation of group I metabotropic glutamate receptors evokes calcium signals and c-jun and c-fos gene expression in human T cells.
Topics: Calcium Signaling; Cells, Cultured; Dose-Response Relationship, Drug; Gene Expression Regulation; Genes, fos; Genes, jun; Glycine; Humans; Jurkat Cells; Receptors, Metabotropic Glutamate; Resorcinols; T-Lymphocytes | 2005 |
Acute up-regulation of glutamate uptake mediated by mGluR5a in reactive astrocytes.
Topics: Amino Acid Transport System X-AG; Analysis of Variance; Animals; Animals, Newborn; Aspartic Acid; Astrocytes; Biotinylation; Blotting, Western; Calcium; Carbachol; Cells, Cultured; Cholinergic Agonists; Chromones; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 2; Glutamic Acid; Glycine; Immunohistochemistry; Methoxyhydroxyphenylglycol; Phorbol Esters; Protein Kinase C; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium; Tritium; Type C Phospholipases | 2005 |
Signal transduction pathways of group I metabotropic glutamate receptor-induced long-term depression at sensory spinal synapses.
Topics: Animals; Benzoates; Calcium; Disease Models, Animal; Excitatory Amino Acid Antagonists; Female; Glycine; Intracellular Space; Long-Term Synaptic Depression; Male; Neurons, Afferent; Nociceptors; Patch-Clamp Techniques; Posterior Horn Cells; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols; Signal Transduction; Spinal Cord; Synapses; Thapsigargin | 2005 |
A TOP at the Synapse.
Topics: Animals; Dentate Gyrus; Electrodes, Implanted; Excitatory Amino Acid Agonists; Glycine; Long-Term Potentiation; Long-Term Synaptic Depression; Neuronal Plasticity; Peptide Elongation Factor 1; Rats; Resorcinols; RNA, Messenger; Synapses | 2005 |
The inhibition of glycogen synthase kinase 3beta by a metabotropic glutamate receptor 5 mediated pathway confers neuroprotection to Abeta peptides.
Topics: Amyloid beta-Peptides; Animals; Benzoates; Cells, Cultured; Chromones; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hippocampus; In Vitro Techniques; Indoles; Methoxyhydroxyphenylglycol; Mice; Mice, Inbred C57BL; Microtubule-Associated Proteins; Morpholines; Neurons; Oncogene Protein v-akt; Peptide Fragments; Phosphorylation; Pyridines; Rats; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Serine; Signal Transduction | 2005 |
The effect of mGlu5 receptor positive allosteric modulators on signaling molecules in brain slices.
Topics: Action Potentials; Animals; Benzamides; Brain; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Antagonists; Extracellular Signal-Regulated MAP Kinases; Glycine; Hippocampus; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Phosphorylation; Phthalimides; Pyramidal Cells; Rabbits; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Resorcinols; Signal Transduction | 2006 |
IP3 receptor in the hair cells of frog semicircular canal and its possible functional role.
Topics: Action Potentials; Animals; Boron Compounds; Calcium; Calcium Channels; Calcium-Transporting ATPases; Excitatory Postsynaptic Potentials; Glycine; Hair Cells, Vestibular; Immunohistochemistry; Indoles; Inositol 1,4,5-Trisphosphate Receptors; Intracellular Space; Rana esculenta; Receptors, Cytoplasmic and Nuclear; Receptors, Metabotropic Glutamate; Resorcinols; Sarcoplasmic Reticulum; Semicircular Canals | 2006 |
mGluR1/5 subtype-specific calcium signalling and induction of long-term potentiation in rat hippocampal oriens/alveus interneurones.
Topics: Animals; Benzoates; Calcium; Calcium Signaling; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; In Vitro Techniques; Interneurons; Long-Term Potentiation; Membrane Potentials; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; src-Family Kinases; Synapses; Synaptic Transmission; TRPC Cation Channels | 2006 |
Long-term depression activates transcription of immediate early transcription factor genes: involvement of serum response factor/Elk-1.
Topics: Animals; Binding Sites; ets-Domain Protein Elk-1; Excitatory Amino Acid Agonists; Gene Expression Regulation; Genes, Immediate-Early; Glycine; Hippocampus; Long-Term Synaptic Depression; Mice; Mice, Inbred C57BL; Organ Culture Techniques; Promoter Regions, Genetic; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Resorcinols; Serum Response Factor; Transcriptional Activation | 2006 |
Intracellular messengers involved in spontaneous pain, heat hyperalgesia, and mechanical allodynia induced by intrathecal dihydroxyphenylglycine.
Topics: Animals; Extracellular Signal-Regulated MAP Kinases; Glycine; Hot Temperature; Hyperalgesia; Hyperesthesia; Injections, Spinal; Male; Pain; Protein Kinase C; Rats; Rats, Long-Evans; Resorcinols; Touch | 2006 |
High sensitivity to neuromodulator-activated signaling pathways at physiological [K+] of confocally imaged respiratory center neurons in on-line-calibrated newborn rat brainstem slices.
Topics: Action Potentials; Analgesics, Opioid; Animals; Animals, Newborn; Brain Mapping; Calibration; Glycine; Inhalation; Medulla Oblongata; Microscopy, Confocal; Narcotic Antagonists; Neurons; Neurotransmitter Agents; Organ Culture Techniques; Potassium; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Opioid, mu; Resorcinols; Respiration; Respiratory Center; Rolipram; Signal Transduction; Synaptic Transmission; Thyrotropin-Releasing Hormone | 2006 |
Endogenous mGluR activity suppresses GABAergic transmission in avian cochlear nucleus magnocellularis neurons.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Chickens; Cochlear Nucleus; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Kinetics; Membrane Potentials; Models, Neurological; Neurons; Patch-Clamp Techniques; Receptors, GABA-B; Receptors, Metabotropic Glutamate; Resorcinols; Synapses; Synaptic Transmission; Xanthenes | 2007 |
Group I metabotropic glutamate receptor-induced Ca(2+)-gradients in rat superficial spinal dorsal horn neurons.
Topics: Analysis of Variance; Animals; Animals, Newborn; Calcium; Calcium Channel Blockers; Calcium-Transporting ATPases; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Indoles; Membrane Potentials; Patch-Clamp Techniques; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols; Spinal Cord | 2007 |
Interaction of novel positive allosteric modulators of metabotropic glutamate receptor 5 with the negative allosteric antagonist site is required for potentiation of receptor responses.
Topics: Allosteric Regulation; Allosteric Site; Animals; Benzamides; Binding, Competitive; Cell Line; Drug Synergism; Glycine; Humans; Male; Mutation; Neurons; Pyrazoles; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Substantia Nigra; Substrate Specificity; Subthalamic Nucleus | 2007 |
Decrease in N-methyl-D-aspartic acid receptor-NR2B subunit levels by intrathecal short-hairpin RNA blocks group I metabotropic glutamate receptor-mediated hyperalgesia.
Topics: Animals; Excitatory Amino Acid Antagonists; Gene Silencing; Glycine; Hyperalgesia; Male; Mice; Pain; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Resorcinols; RNA, Small Interfering; Signal Transduction | 2007 |
Motor activity is modulated via different neuronal circuits in rats with chronic liver failure than in normal rats.
Topics: Animals; Behavior, Animal; Brain; Chronic Disease; Dopamine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Humans; Liver Failure; Male; Microdialysis; Motor Activity; Neural Pathways; Neurons; Portacaval Shunt, Surgical; Rats; Rats, Wistar; Resorcinols | 2007 |
Hyperammonaemia alters the mechanisms by which metabotropic glutamate receptors in nucleus accumbens modulate motor function.
Topics: Animals; Disease Models, Animal; Excitatory Amino Acid Agonists; Glycine; Hyperammonemia; Male; Microdialysis; Motor Activity; Neural Pathways; Nucleus Accumbens; Prefrontal Cortex; Quaternary Ammonium Compounds; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols; Substantia Nigra; Thalamus | 2007 |
Functional interactions between presynaptic NMDA receptors and metabotropic glutamate receptors co-expressed on rat and human noradrenergic terminals.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Chromones; Female; Glycine; Hippocampus; Humans; Male; N-Methylaspartate; Norepinephrine; Presynaptic Terminals; Protein Binding; Rats; Rats, Sprague-Dawley; Receptor Cross-Talk; Receptor, Metabotropic Glutamate 5; Receptors, AMPA; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Presynaptic; Resorcinols; Synaptosomes; Tritium | 2007 |
Endocannabinoid signalling triggered by NMDA receptor-mediated calcium entry into rat hippocampal neurons.
Topics: Animals; Animals, Newborn; Calcium Channels; Calcium Signaling; Cannabinoid Receptor Modulators; Cells, Cultured; Chelating Agents; Dose-Response Relationship, Drug; Egtazic Acid; Endocannabinoids; Excitatory Amino Acid Agonists; Glycine; GTP-Binding Protein alpha Subunits, Gq-G11; Hippocampus; Inhibitory Postsynaptic Potentials; Lipoprotein Lipase; Morpholines; Muscarinic Agonists; N-Methylaspartate; Neurons; Oxotremorine; Phospholipase C beta; Pyrazoles; Rats; Receptor, Cannabinoid, CB1; Receptors, Metabotropic Glutamate; Receptors, Muscarinic; Receptors, N-Methyl-D-Aspartate; Resorcinols | 2007 |
Enhanced 3,5-dihydroxyphenylglycine-induced sustained nociceptive behaviors in rats with neuropathy or chronic inflammation.
Topics: Analysis of Variance; Animals; Behavior, Animal; Disease Models, Animal; Excitatory Amino Acid Agonists; Freund's Adjuvant; Functional Laterality; Glycine; Inflammation; Injections, Spinal; Male; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Long-Evans; Resorcinols; Sciatic Neuropathy; Time Factors | 2007 |
TrpC3/C7 and Slo2.1 are molecular targets for metabotropic glutamate receptor signaling in rat striatal cholinergic interneurons.
Topics: Acetylcholine; Analysis of Variance; Animals; Animals, Newborn; Cell Line, Transformed; Corpus Striatum; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Agents; Gene Expression Regulation; Glycine; Humans; In Vitro Techniques; Interneurons; Membrane Potentials; Patch-Clamp Techniques; Potassium Channels; Potassium Channels, Sodium-Activated; Potassium Chloride; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols; Signal Transduction; Transfection; TRPC Cation Channels | 2007 |
mGluR5 antagonists that block calcium mobilization in vitro also reverse (S)-3,5-DHPG-induced hyperalgesia and morphine antinociceptive tolerance in vivo.
Topics: Analgesics, Opioid; Animals; Calcium Signaling; Central Nervous System; Dose-Response Relationship, Drug; Drug Tolerance; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Hyperalgesia; Male; Mice; Morphine; Nociceptors; Pain; Placebo Effect; Pyridines; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Synaptic Transmission | 2008 |
Analgesic activity of metabotropic glutamate receptor 1 antagonists on spontaneous post-operative pain in rats.
Topics: Analgesics, Non-Narcotic; Animals; Calcium; Cell Membrane; Cerebellum; Dimethylamines; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Exploratory Behavior; Fluorometry; Glycine; Heterocyclic Compounds, 3-Ring; Hindlimb; Male; Molecular Structure; Morphine; Pain, Postoperative; Pyridines; Pyrimidinones; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols; Rotarod Performance Test; Thiophenes; Tritium | 2008 |
Face-washing behavior induced by the group I metabotropic glutamate receptor agonist (S)-3,5-DHPG in mice is mediated by mGlu1 receptor.
Topics: Animals; Behavior, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Glycine; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Receptors, Metabotropic Glutamate; Resorcinols; Seizures | 2008 |
Presynaptic mGlu1 and mGlu5 autoreceptors facilitate glutamate exocytosis from mouse cortical nerve endings.
Topics: Animals; Aspartic Acid; Cerebral Cortex; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agents; Exocytosis; Gene Expression; Glutamic Acid; Glycine; Male; Mice; Mice, Inbred BALB C; Mice, Knockout; Potassium Chloride; Presynaptic Terminals; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Synaptosomes; Syntaxin 1; Tritium; Vesicular Glutamate Transport Protein 1 | 2008 |
Protein kinase C signaling in the hypothalamic arcuate nucleus regulates sexual receptivity in female rats.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Biological Transport; Estradiol; Estrogen Receptor alpha; Female; Glycine; Hypothalamus; Immunoblotting; Immunohistochemistry; Immunoprecipitation; Male; Phorbol 12,13-Dibutyrate; Phosphoproteins; Protein Kinase C; Rats; Rats, Long-Evans; Receptors, Metabotropic Glutamate; Receptors, Opioid, mu; Resorcinols; Sexual Behavior, Animal; Signal Transduction | 2008 |
Infrared-guided laser stimulation as a tool for elucidating the synaptic site of expression of long-term synaptic plasticity.
Topics: Animals; Electrophysiology; Excitatory Postsynaptic Potentials; Glutamates; Glycine; Infrared Rays; Lasers; Long-Term Synaptic Depression; Resorcinols; Synapses | 2007 |
Neuronal pentraxins modulate cocaine-induced neuroadaptations.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; C-Reactive Protein; Cocaine; Conditioning, Psychological; Crosses, Genetic; Extracellular Matrix; Gene Deletion; Glutamic Acid; Glycine; Locomotion; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Knockout; Motor Activity; Nerve Tissue Proteins; Neurons; Receptors, AMPA; Resorcinols; Synapses | 2009 |
AMPA and metabotropic glutamate receptors cooperatively generate inspiratory-like depolarization in mouse respiratory neurons in vitro.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Calcium Channels; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Inositol 1,4,5-Trisphosphate Receptors; Membrane Potentials; Mice; Mice, Inbred C57BL; Neurons; Receptors, AMPA; Receptors, Metabotropic Glutamate; Resorcinols; Respiratory Center; Sodium Channel Blockers; Tetrodotoxin | 2008 |
Tyrosine dephosphorylation regulates AMPAR internalisation in mGluR-LTD.
Topics: Amino Acid Sequence; Animals; Endocytosis; Excitatory Amino Acid Agonists; Female; Glycine; Hippocampus; Long-Term Synaptic Depression; Molecular Sequence Data; N-Methylaspartate; Phosphorylation; Protein Subunits; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Metabotropic Glutamate; Resorcinols; Sequence Alignment; Synapses; Tyrosine | 2009 |
Identification of potential pharmacological targets by analysis of the comprehensive G protein-coupled receptor repertoire in the four cardiac chambers.
Topics: Animals; Blotting, Western; Calcium; Gene Expression Profiling; Glycine; Male; Mice; Mice, Inbred C57BL; Myocardium; Receptors, G-Protein-Coupled; Receptors, Metabotropic Glutamate; Resorcinols; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2009 |
Excitatory actions of noradrenaline and metabotropic glutamate receptor activation in granule cells of the accessory olfactory bulb.
Topics: Action Potentials; Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Benzoates; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glycine; In Vitro Techniques; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Neurons; Norepinephrine; Olfactory Bulb; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha-1; Receptors, Metabotropic Glutamate; Resorcinols | 2009 |
Evidence group I mGluR drugs modulate the activation profile of lipopolysaccharide-exposed microglia in culture.
Topics: Animals; Animals, Newborn; Cells, Cultured; Drug Synergism; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Ligands; Lipopolysaccharides; Microglia; Nitrites; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols; Tumor Necrosis Factor-alpha | 2009 |
Correlation of receptor occupancy of metabotropic glutamate receptor subtype 1 (mGluR1) in mouse brain with in vivo activity of allosteric mGluR1 antagonists.
Topics: Allosteric Regulation; Animals; Behavior, Animal; Brain; CHO Cells; Cricetinae; Cricetulus; Glycine; In Vitro Techniques; Male; Mice; Mice, Inbred ICR; Mice, Knockout; Protein Binding; Receptors, Metabotropic Glutamate; Recombinant Proteins; Resorcinols; Triazoles | 2009 |
Novel mGluR- and CB1R-independent suppression of GABA release caused by a contaminant of the group I metabotropic glutamate receptor agonist, DHPG.
Topics: Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glycine; Hippocampus; In Vitro Techniques; Rats; Receptor, Cannabinoid, CB1; Receptors, Metabotropic Glutamate; Resorcinols; Synaptic Transmission | 2009 |
Deranged calcium signaling and neurodegeneration in spinocerebellar ataxia type 2.
Topics: Animals; Ataxins; Calcium; Calcium Channel Blockers; Calcium Signaling; Cell Death; Cells, Cultured; Chlorocebus aethiops; COS Cells; Dantrolene; Excitatory Amino Acid Agents; Glutamic Acid; Glycine; Inositol 1,4,5-Trisphosphate Receptors; Mice; Mice, Transgenic; Motor Activity; Nerve Degeneration; Nerve Tissue Proteins; Purkinje Cells; Resorcinols; Ryanodine; Spinocerebellar Ataxias | 2009 |
Modulation of intracellular calcium mobilization and GABAergic currents through subtype-specific metabotropic glutamate receptors in neonatal rat hippocampus.
Topics: Animals; Animals, Newborn; CA1 Region, Hippocampal; CA3 Region, Hippocampal; Calcium; Chromones; Excitatory Amino Acid Agents; gamma-Aminobutyric Acid; Glycine; Hippocampus; In Vitro Techniques; Interneurons; Intracellular Space; Phenylacetates; Pyramidal Cells; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, GABA-A; Receptors, Metabotropic Glutamate; Resorcinols | 2010 |
Developmental alterations of DHPG-induced long-term depression of corticostriatal synaptic transmission: switch from NMDA receptor-dependent towards CB1 receptor-dependent plasticity.
Topics: Animals; Corpus Striatum; Electrophysiology; Excitatory Amino Acid Agents; Glycine; Long-Term Synaptic Depression; Mice; Mice, Inbred C57BL; Neuronal Plasticity; Receptor, Cannabinoid, CB1; Receptors, N-Methyl-D-Aspartate; Resorcinols; Reverse Transcriptase Polymerase Chain Reaction; Synaptic Transmission | 2009 |
GABA(A) receptor inhibition does not affect mGluR-dependent LTD at hippocampal Schaffer collateral-CA1 synapses.
Topics: Animals; CA1 Region, Hippocampal; Electric Stimulation; Excitatory Amino Acid Agonists; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glycine; Hippocampus; In Vitro Techniques; Interneurons; Long-Term Synaptic Depression; Male; Neural Inhibition; Pyramidal Cells; Pyridazines; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, Metabotropic Glutamate; Resorcinols; Synapses | 2009 |
An interaction of oxytocin receptors with metabotropic glutamate receptors in hypothalamic astrocytes.
Topics: Animals; Astrocytes; Benzoates; Calcium; Cells, Cultured; Estradiol; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glycine; Hypothalamus; Oxytocin; Rats; Rats, Long-Evans; Receptors, Metabotropic Glutamate; Receptors, Oxytocin; Resorcinols; Signal Transduction; Time Factors | 2009 |
Activation of group I metabotropic glutamate receptors leads to brain-derived neurotrophic factor expression in rat C6 cells.
Topics: Animals; Brain-Derived Neurotrophic Factor; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Line, Tumor; Chromones; Glycine; Protein Kinase C; Pyridines; Rats; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; RNA, Messenger; Signal Transduction | 2009 |
Antinociception by motor cortex stimulation in the neuropathic rat: does the locus coeruleus play a role?
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Anesthetics, Local; Animals; Autonomic Pathways; Electric Stimulation Therapy; Electrophysiology; Excitatory Amino Acid Agonists; Glycine; Hot Temperature; Injections, Spinal; Lidocaine; Ligation; Locus Coeruleus; Male; Microinjections; Motor Cortex; Pain; Pain Management; Peripheral Nervous System Diseases; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Reflex; Resorcinols; Spinal Cord; Spinal Nerves | 2010 |
A new multiple-drug applicator with minimal drug cross-talk, leakage, and consumption.
Topics: Animals; Cells, Cultured; Drug Evaluation, Preclinical; Eosine Yellowish-(YS); Equipment Failure; Fluorescent Dyes; Glycine; In Vitro Techniques; Isoquinolines; Mice; Patch-Clamp Techniques; Pharmaceutical Preparations; Pharmacology; Purkinje Cells; Receptors, Metabotropic Glutamate; Resorcinols | 2010 |
Ameliorative effect of a hippocampal metabotropic glutamate- receptor agonist on histamine H1 receptor antagonist-induced memory deficit in rats.
Topics: Aminobutyrates; Animals; Drug Interactions; Excitatory Amino Acid Agonists; Glycine; Hippocampus; Histamine H1 Antagonists; Male; Maze Learning; Memory Disorders; Memory, Short-Term; Proline; Pyrilamine; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols; Theta Rhythm | 2010 |
[Activation of mGluRI in neutrophils promotes the adherence of neutrophils to endothelial cells].
Topics: Benzoates; CD11a Antigen; Cell Adhesion; Endothelial Cells; Glycine; Human Umbilical Vein Endothelial Cells; Humans; Neutrophils; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols | 2010 |
Reactivation of fear memory renders consolidated amygdala synapses labile.
Topics: Amygdala; Analysis of Variance; Animals; Conditioning, Classical; Excitatory Amino Acid Agonists; Fear; Glycine; Long-Term Synaptic Depression; Male; Memory; Neural Pathways; Neurons; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols; Synapses; Synaptic Transmission; Thalamus | 2010 |
Evaluation of cannabinoid receptor 2 and metabotropic glutamate receptor 1 functional responses using a cell impedance-based technology.
Topics: Analgesics; Animals; Benzimidazoles; Biological Assay; Calcium; Cannabinoids; CHO Cells; Chromones; Cricetinae; Cricetulus; Cyclic AMP; Cyclohexanols; Cycloleucine; Electric Impedance; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Indoles; Naphthalenes; Neuroprotective Agents; Quinolines; Quisqualic Acid; Receptor, Cannabinoid, CB2; Receptors, Metabotropic Glutamate; Resorcinols; Signal Transduction; Thiazoles | 2010 |
NMDA receptor, PKC and ERK prevent fos expression induced by the activation of group I metabotropic glutamate receptors in the spinal trigeminal subnucleus oralis.
Topics: Animals; Benzoates; Extracellular Signal-Regulated MAP Kinases; Female; Flavonoids; Glycine; Indoles; Male; Maleimides; Neurons; Protein Kinase C; Proto-Oncogene Proteins c-fos; Rats; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Resorcinols; Trigeminal Nucleus, Spinal | 2010 |
Endocannabinoids potentiate synaptic transmission through stimulation of astrocytes.
Topics: Animals; Animals, Newborn; Astrocytes; Benzoates; Biophysics; Calcium; Cannabinoid Receptor Modulators; Chelating Agents; Drug Interactions; Egtazic Acid; Electric Stimulation; Endocannabinoids; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; Hippocampus; In Vitro Techniques; Mice; Mice, Inbred C57BL; Mice, Knockout; Patch-Clamp Techniques; Photolysis; Piperidines; Pyramidal Cells; Pyrazoles; Pyridines; Receptor, Cannabinoid, CB1; Resorcinols; Synaptic Transmission; Thapsigargin | 2010 |
Caveolin-1 knockout mice exhibit impaired induction of mGluR-dependent long-term depression at CA3-CA1 synapses.
Topics: Animals; Antibiotics, Antineoplastic; Butadienes; Caveolin 1; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Extracellular Signal-Regulated MAP Kinases; Glycine; Hippocampus; Long-Term Synaptic Depression; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitriles; Patch-Clamp Techniques; Receptors, Metabotropic Glutamate; Resorcinols; Signal Transduction; Sirolimus; Synapses; TOR Serine-Threonine Kinases | 2010 |
Short- and long-term depression at glutamatergic synapses on hippocampal interneurons by group I mGluR activation.
Topics: Animals; Calcium Channels; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Glycine; Hippocampus; Interneurons; Methoxyhydroxyphenylglycol; Neuronal Plasticity; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols; Signal Transduction; Synapses; Synaptic Transmission | 2011 |
Group I mGluR agonist-evoked long-term potentiation in hippocampal oriens interneurons.
Topics: Animals; Benzoates; Electric Stimulation; Electrodes, Implanted; Electrophysiological Phenomena; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Glycine; Hippocampus; Interneurons; Long-Term Potentiation; Male; Phenylacetates; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Metabotropic Glutamate; Resorcinols | 2011 |
Reverse engineering of synaptic plasticity in the hippocampus.
Topics: Animals; Glycine; Hippocampus; Long-Term Synaptic Depression; Neuronal Plasticity; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols | 2011 |
Epoxyeicosatrienoic acid-dependent cerebral vasodilation evoked by metabotropic glutamate receptor activation in vivo.
Topics: 8,11,14-Eicosatrienoic Acid; Adenosine A2 Receptor Antagonists; Analysis of Variance; Animals; Arterioles; Blood Flow Velocity; Cerebral Arteries; Cerebral Cortex; Cerebrovascular Circulation; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Epoxide Hydrolases; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Heme Oxygenase (Decyclizing); Hydroxyeicosatetraenoic Acids; Laser-Doppler Flowmetry; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Rats; Rats, Wistar; Receptor, Adenosine A2B; Receptors, Metabotropic Glutamate; Regional Blood Flow; Resorcinols; Signal Transduction; Time Factors; Vasodilation; Vasodilator Agents | 2011 |
Prolonged postinhibitory rebound firing in the cerebellar nuclei mediated by group I metabotropic glutamate receptor potentiation of L-type calcium currents.
Topics: Action Potentials; Animals; Calcium Channels, L-Type; Cerebellar Nuclei; gamma-Aminobutyric Acid; Glycine; Inhibitory Postsynaptic Potentials; Membrane Potentials; Methoxyhydroxyphenylglycol; Mice; Neural Inhibition; Neurons; Patch-Clamp Techniques; Receptors, Metabotropic Glutamate; Resorcinols; Synapses; Synaptic Transmission; Thiophenes | 2011 |
Role for the membrane receptor guanylyl cyclase-C in attention deficiency and hyperactive behavior.
Topics: Amphetamine; Animals; Attention; Attention Deficit Disorder with Hyperactivity; Behavior, Animal; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Disease Models, Animal; Dopamine; Enzyme Activation; Gastrointestinal Hormones; Glycine; Impulsive Behavior; Ligands; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Natriuretic Peptides; Neurons; Patch-Clamp Techniques; Receptors, Enterotoxin; Receptors, Glutamate; Receptors, Guanylate Cyclase-Coupled; Receptors, Muscarinic; Receptors, Peptide; Resorcinols; Signal Transduction; Substantia Nigra; Ventral Tegmental Area | 2011 |
Reversible plasticity of fear memory-encoding amygdala synaptic circuits even after fear memory consolidation.
Topics: Amygdala; Animals; Conditioning, Classical; Excitatory Amino Acid Agents; Excitatory Postsynaptic Potentials; Extinction, Psychological; Fear; Glycine; Long-Term Potentiation; Male; Memory; Neural Pathways; Neuronal Plasticity; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Resorcinols; Synaptic Potentials; Synaptic Transmission; Thalamus | 2011 |
Molecular changes associated with hippocampal long-lasting depression induced by the serine protease subtilisin-A.
Topics: Animals; Anisomycin; Benzoates; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; Hippocampus; Long-Term Synaptic Depression; Male; Mice; Phosphoprotein Phosphatases; Protein Synthesis Inhibitors; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols; rhoB GTP-Binding Protein; Subtilisins | 2011 |
Examination of a role for metabotropic glutamate receptor 5 in the medial prefrontal cortex in cocaine sensitization in rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Benzimidazoles; Central Nervous System Sensitization; Cocaine; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Male; Microinjections; Motor Activity; Prefrontal Cortex; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, AMPA; Receptors, Metabotropic Glutamate; Resorcinols; Thiazoles; Ventral Tegmental Area | 2012 |
Functional metabotropic glutamate receptors 1 and 5 are expressed in murine podocytes.
Topics: Animals; Apoptosis; Cells, Cultured; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Doxorubicin; Glycine; In Vitro Techniques; Male; Mice; Mice, Inbred BALB C; Models, Animal; Podocytes; Proteinuria; Puromycin Aminonucleoside; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols | 2012 |
Involvement of metabotropic glutamate receptor 5 in cardiomyocyte differentiation from mouse embryonic stem cells.
Topics: Animals; Calcium Channels, L-Type; Calcium Channels, T-Type; Calcium Signaling; Carrier Proteins; Cell Differentiation; Cell Line; Cell Survival; Coculture Techniques; Embryoid Bodies; Female; Gene Expression; Gene Knockdown Techniques; Glycine; GTP Phosphohydrolases; Homer Scaffolding Proteins; Male; Mice; Mice, Inbred ICR; Myocytes, Cardiac; Nerve Tissue Proteins; Phosphatidylinositol 3-Kinases; Pyridines; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; RNA Interference | 2012 |
RGS4 overexpression in the rat dorsal striatum modulates mGluR5- and amphetamine-mediated behavior and signaling.
Topics: Amphetamine; Animals; Behavior, Animal; Central Nervous System Stimulants; Corpus Striatum; Excitatory Amino Acid Agonists; Glycine; Male; MAP Kinase Signaling System; Proto-Oncogene Proteins c-akt; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; RGS Proteins; Thiazoles | 2012 |
Single-molecule imaging of translational output from individual RNA granules in neurons.
Topics: Animals; Bacterial Proteins; Cells, Cultured; Cytoskeletal Proteins; Fragile X Mental Retardation Protein; Glycine; Hippocampus; Luminescent Proteins; Molecular Imaging; Nerve Tissue Proteins; Neurons; Protein Biosynthesis; Rats; Resorcinols; RNA | 2012 |
Effect of (S)-3,5-DHPG on microRNA expression in mouse brain.
Topics: Animals; Brain; Excitatory Amino Acid Agonists; Gene Expression Regulation; Glycine; Injections, Intraventricular; Male; Mice; Mice, Inbred C57BL; MicroRNAs; Receptors, Metabotropic Glutamate; Resorcinols | 2012 |
Activation of amygdalar metabotropic glutamate receptors modulates anxiety, and risk assessment behaviors in ovariectomized estradiol-treated female rats.
Topics: Amygdala; Animals; Anxiety; Behavior, Animal; Estradiol; Female; Glycine; Indans; Male; Maze Learning; Ovariectomy; Ovary; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Receptors, Metabotropic Glutamate; Resorcinols | 2012 |
Effect of prenatal hypobaric hypoxia on glutamatergic signal transduction in rat brain.
Topics: Animals; Brain; Calcium; Diglycerides; Excitatory Amino Acid Agents; Female; Fetal Hypoxia; Glycine; Inosine Triphosphate; Male; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols; Signal Transduction; Tissue Culture Techniques | 2011 |
Receptor-selective diffusion barrier enhances sensitivity of astrocytic processes to metabotropic glutamate receptor stimulation.
Topics: Algorithms; Animals; Astrocytes; Calcium; Calcium Signaling; Calmodulin; Cells, Cultured; Coculture Techniques; Diffusion; Excitatory Amino Acid Agonists; Fluorescence Recovery After Photobleaching; Glycine; Green Fluorescent Proteins; Hippocampus; Immunohistochemistry; Kinetics; Neurons; Quantum Dots; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Recombinant Fusion Proteins; Resorcinols; Transfection | 2012 |
mGlu5R promotes glutamate AMPA receptor phosphorylation via activation of PKA/DARPP-32 signaling in striatopallidal medium spiny neurons.
Topics: Animals; Corpus Striatum; Cyclic AMP-Dependent Protein Kinases; Dopamine and cAMP-Regulated Phosphoprotein 32; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Phosphorylation; Purinergic P1 Receptor Antagonists; Pyridines; Receptor, Adenosine A2A; Receptor, Metabotropic Glutamate 5; Receptors, AMPA; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Metabotropic Glutamate; Resorcinols; Signal Transduction; Triazines; Triazoles | 2013 |
NMDA receptors with incomplete Mg²⁺ block enable low-frequency transmission through the cerebellar cortex.
Topics: Action Potentials; Animals; Cerebellar Cortex; Excitatory Postsynaptic Potentials; Glycine; In Vitro Techniques; Magnesium; Male; Nerve Fibers; Neurons; Purkinje Cells; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Resorcinols; Synaptic Transmission | 2012 |
Group I metabotropic glutamate autoreceptors induce abnormal glutamate exocytosis in a mouse model of amyotrophic lateral sclerosis.
Topics: Amyotrophic Lateral Sclerosis; Animals; Aspartic Acid; Autoreceptors; Calcium; Disease Models, Animal; Excitatory Amino Acid Antagonists; Exocytosis; Female; Glutamic Acid; Glycine; Humans; Inositol Phosphates; Lumbar Vertebrae; Male; Mice; Mice, Neurologic Mutants; Mice, Transgenic; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Spinal Cord; Superoxide Dismutase; Superoxide Dismutase-1; Synaptosomes | 2013 |
Mild activation of poly(ADP-ribose) polymerase (PARP) is neuroprotective in rat hippocampal slice models of ischemic tolerance.
Topics: Amino Acid Chloromethyl Ketones; Animals; Caspase 3; Caspase 7; Caspase Inhibitors; Cell Death; Cell Hypoxia; Cells, Cultured; Glucose; Glycine; Hippocampus; Ischemic Preconditioning; Isoquinolines; MAP Kinase Signaling System; N-Methylaspartate; Neurons; Neuroprotective Agents; Phenanthrenes; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Rats; Rats, Wistar; Resorcinols; Thiophenes | 2012 |
Role of metabotropic glutamate receptor 1 in the basolateral amygdala-driven prefrontal cortical deactivation in inflammatory pain in the rat.
Topics: Action Potentials; Amygdala; Animals; Bicuculline; Carrageenan; Chromones; Disease Models, Animal; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Formaldehyde; GABA Antagonists; Gene Expression; Glycine; Male; Neural Inhibition; Neural Pathways; Neuronal Plasticity; Pain; Physical Stimulation; Prefrontal Cortex; Pyramidal Cells; Pyridines; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols | 2013 |
Dysregulation of mitochondrial calcium signaling and superoxide flashes cause mitochondrial genomic DNA damage in Huntington disease.
Topics: Animals; Bradykinin; Calcium; Calcium Channels; Calcium Signaling; DNA Damage; DNA, Mitochondrial; Embryo, Mammalian; Female; Fibroblasts; Genome, Mitochondrial; Glycine; Humans; Huntington Disease; Inositol 1,4,5-Trisphosphate Receptors; Mice; Mice, Transgenic; Mitochondria; Neostriatum; Neurons; Resorcinols; Superoxides | 2013 |
Group I mGluRs evoke K-ATP current by intracellular Ca2+ mobilization in rat subthalamus neurons.
Topics: Animals; Calcium; Glutamic Acid; Glycine; In Vitro Techniques; Ion Channel Gating; KATP Channels; Male; Membrane Potentials; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols; Subthalamic Nucleus | 2013 |
Hippocampal Gαq/₁₁ but not Gαo-coupled receptors are altered in aging.
Topics: Aging; Animals; Baclofen; CA1 Region, Hippocampal; Calcium; Excitatory Amino Acid Agonists; GABA-B Receptor Agonists; Glycine; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gq-G11; Hippocampus; Learning; Male; Muscarinic Agonists; Oxotremorine; Rats; Resorcinols; Spatial Behavior | 2013 |
Metabotropic glutamate receptor I (mGluR1) antagonism impairs cocaine-induced conditioned place preference via inhibition of protein synthesis.
Topics: Animals; Cocaine; Conditioning, Psychological; Cycloheximide; Dopaminergic Neurons; Drug Interactions; Extracellular Signal-Regulated MAP Kinases; Glycine; Inhibitory Postsynaptic Potentials; Long-Term Synaptic Depression; Male; Microinjections; Nerve Tissue Proteins; Peptide Chain Elongation, Translational; Protein Synthesis Inhibitors; Quinolines; Rats; Receptor, Cannabinoid, CB1; Receptors, Metabotropic Glutamate; Resorcinols; Signal Transduction; Synapses; TOR Serine-Threonine Kinases; Ventral Tegmental Area | 2013 |
Activation of both Group I and Group II metabotropic glutamatergic receptors suppress retinogeniculate transmission.
Topics: Animals; Cerebral Cortex; Cyclopropanes; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Geniculate Bodies; Glycine; Mice; Neural Inhibition; Neural Pathways; Photic Stimulation; Receptors, Metabotropic Glutamate; Resorcinols; Retina; Synaptic Transmission; Thalamus; Visual Pathways | 2013 |
Long lasting protein synthesis- and activity-dependent spine shrinkage and elimination after synaptic depression.
Topics: Animals; Animals, Newborn; Cycloheximide; Dendritic Spines; Excitatory Postsynaptic Potentials; Glycine; Long-Term Synaptic Depression; Mice; Mice, Inbred C57BL; Molecular Imaging; Patch-Clamp Techniques; Protein Biosynthesis; Pyramidal Cells; Receptors, Metabotropic Glutamate; Resorcinols; Synapses; Synaptic Transmission; Tissue Culture Techniques | 2013 |
Dual depolarization responses generated within the same lateral septal neurons by TRPC4-containing channels.
Topics: Action Potentials; Animals; Calcium; Calcium Signaling; Excitatory Amino Acid Agonists; Glycine; Mice; Mice, Inbred C57BL; Neurons; Receptor, Metabotropic Glutamate 5; Resorcinols; Septal Nuclei; Sodium; TRPC Cation Channels | 2014 |
Activation of lateral hypothalamic mGlu1 and mGlu5 receptors elicits feeding in rats.
Topics: Animals; Benzimidazoles; Benzopyrans; Cycloleucine; Dose-Response Relationship, Drug; Eating; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Hypothalamus; Male; Phenylacetates; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Thiazoles; Time Factors | 2014 |
Type 1 metabotropic glutamate receptors (mGlu1) trigger the gating of GluD2 delta glutamate receptors.
Topics: Animals; Calcium Signaling; Cerebellum; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Glycine; HEK293 Cells; Humans; Ion Channel Gating; Male; Mice; Mice, Inbred C57BL; Purkinje Fibers; Receptors, Glutamate; Receptors, Metabotropic Glutamate; Resorcinols | 2014 |
Function of mGlu1 receptors in the modulation of nociceptive processing in the thalamus.
Topics: Action Potentials; Animals; Benzoates; Carbamates; Cold Temperature; Excitatory Amino Acid Agents; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Hot Temperature; Male; Neural Pathways; Neurons; Nociception; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols; Somatosensory Cortex; Thalamus; Xanthenes | 2014 |
Interaction of DHPG-LTD and synaptic-LTD at senescent CA3-CA1 hippocampal synapses.
Topics: Aging; Animals; CA1 Region, Hippocampal; CA3 Region, Hippocampal; Calcium Channel Blockers; Calcium Channels, L-Type; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Indans; Long-Term Synaptic Depression; Male; Nifedipine; Rats; Rats, Inbred F344; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Resorcinols; Synapses | 2014 |
Loss of long-term depression in the insular cortex after tail amputation in adult mice.
Topics: Amputation, Surgical; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cerebral Cortex; Cyclic AMP-Dependent Protein Kinases; Electric Stimulation; Glycine; Long-Term Synaptic Depression; Male; Mice; Mice, Inbred C57BL; Protein Kinase C; Receptors, Metabotropic Glutamate; Resorcinols; Synaptic Transmission; Tail | 2014 |
Group I metabotropic glutamate receptor-mediated activation of PKC gamma in the nucleus accumbens core promotes the reinstatement of cocaine seeking.
Topics: Animals; Benzimidazoles; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Nucleus Accumbens; Phosphorylation; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-alpha; Pyridines; Rats; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Thiazoles | 2015 |
Enhanced excitatory synaptic network activity following transient group I metabotropic glutamate activation.
Topics: Animals; CA3 Region, Hippocampal; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Glycine; Miniature Postsynaptic Potentials; Nerve Net; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols; Synapses | 2014 |
Differential roles of signal transduction mechanisms in long-term potentiation of excitatory synaptic transmission induced by activation of group I mGluRs in the spinal trigeminal subnucleus oralis.
Topics: Animals; Calcium Signaling; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Female; Glycine; Intracellular Signaling Peptides and Proteins; Long-Term Potentiation; Male; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Signal Transduction; Trigeminal Nucleus, Spinal | 2014 |
Cocaine Withdrawal Impairs mGluR5-Dependent Long-Term Depression in Nucleus Accumbens Shell Neurons of Both Direct and Indirect Pathways.
Topics: Animals; Benzamides; Chromones; Cocaine; Cocaine-Related Disorders; Dopaminergic Neurons; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Genes, Reporter; Glycine; Imidazoles; Long-Term Synaptic Depression; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nerve Tissue Proteins; Nucleus Accumbens; Pyrazoles; Pyridazines; Pyridines; Receptor, Metabotropic Glutamate 5; Receptors, Dopamine D1; Receptors, Dopamine D2; Resorcinols; Substance Withdrawal Syndrome | 2015 |
Site selective activation of lateral hypothalamic mGluR1 and R5 receptors elicits feeding in rats.
Topics: Amygdala; Animals; Dose-Response Relationship, Drug; Eating; Excitatory Amino Acid Agonists; Glycine; Hypothalamic Area, Lateral; Male; Mediodorsal Thalamic Nucleus; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Satiation; Substantia Nigra; Thalamus | 2015 |
Peripheral group I metabotropic glutamate receptor activation leads to muscle mechanical hyperalgesia through TRPV1 phosphorylation in the rat.
Topics: A Kinase Anchor Proteins; Animals; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; Glycine; Hyperalgesia; Male; Masseter Muscle; Myalgia; Neurons; Phosphorylation; Protein Kinase C; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Touch; Trigeminal Ganglion; TRPV Cation Channels | 2015 |
Group I metabotropic glutamate receptor agonist DHPG modulates Kir4.1 protein and mRNA in cultured rat retinal Müller cells.
Topics: Animals; Animals, Newborn; Cell Membrane; Cells, Cultured; Ependymoglial Cells; Glial Fibrillary Acidic Protein; Gliosis; Glycine; Potassium Channels, Inwardly Rectifying; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols; RNA, Messenger | 2015 |
Preconditioning effect of (S)-3,5-dihydroxyphenylglycine on ischemic injury in middle cerebral artery occluded Sprague-Dawley rats.
Topics: Animals; Brain Infarction; Brain Ischemia; Glycine; Infarction, Middle Cerebral Artery; Injections, Spinal; Male; Neuroprotective Agents; Phosphopyruvate Hydratase; Rats, Sprague-Dawley; Resorcinols; Stereoisomerism | 2015 |
Induction of cannabinoid- and N-methyl-D-aspartate receptor-mediated long-term depression in the nucleus accumbens and dorsolateral striatum is region and age dependent.
Topics: Animals; Benzoxazines; Cannabinoid Receptor Agonists; Corpus Striatum; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Glycine; Long-Term Synaptic Depression; Male; Mice, Inbred C57BL; Morpholines; Naphthalenes; Nerve Tissue Proteins; Nucleus Accumbens; Receptor, Cannabinoid, CB1; Receptors, N-Methyl-D-Aspartate; Resorcinols; Tissue Culture Techniques | 2015 |
Costimulation of AMPA and metabotropic glutamate receptors underlies phospholipase C activation by glutamate in hippocampus.
Topics: Animals; Calcium; Calcium Channels, L-Type; Enzyme Activation; Glutamic Acid; Glycine; Hippocampus; Long-Term Synaptic Depression; Male; Rats; Receptor, Metabotropic Glutamate 5; Receptors, AMPA; Receptors, Metabotropic Glutamate; Resorcinols; Signal Transduction; Type C Phospholipases | 2015 |
Detrimental effects of postnatal exposure to propofol on memory and hippocampal LTP in mice.
Topics: Anesthetics, Intravenous; Animals; Animals, Newborn; Chromones; Conditioning, Psychological; Disks Large Homolog 4 Protein; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Agents; Excitatory Postsynaptic Potentials; Female; Glycine; Guanylate Kinases; Hippocampus; Long-Term Potentiation; Male; Membrane Proteins; Memory; Mice, Inbred C57BL; Morpholines; Phosphorylation; Propofol; Proto-Oncogene Proteins c-akt; Resorcinols; Synaptic Transmission; Tissue Culture Techniques | 2015 |
Type-1, but Not Type-5, Metabotropic Glutamate Receptors are Coupled to Polyphosphoinositide Hydrolysis in the Retina.
Topics: Animals; Cattle; Glycine; Hydrolysis; Inositol Phosphates; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Transgenic; Phosphatidylinositol Phosphates; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Retina; Signal Transduction | 2016 |
Layer-specific potentiation of network GABAergic inhibition in the CA1 area of the hippocampus.
Topics: Animals; Glycine; Hippocampus; In Vitro Techniques; Inositol 1,4,5-Trisphosphate Receptors; Male; Mice; Mice, Inbred C57BL; Patch-Clamp Techniques; Receptors, GABA-A; Receptors, Metabotropic Glutamate; Resorcinols; Synaptic Potentials | 2016 |
The Metabotropic Glutamate Receptor Subtype 1 Mediates Experience-Dependent Maintenance of Mature Synaptic Connectivity in the Visual Thalamus.
Topics: Animals; Carbamates; Geniculate Bodies; Glycine; Mice; Mice, Knockout; Receptors, Metabotropic Glutamate; Resorcinols; Retina; Sensory Deprivation; Synapses; Thalamus; Visual Pathways; Xanthenes | 2016 |
ASIC1a regulates insular long-term depression and is required for the extinction of conditioned taste aversion.
Topics: Acid Sensing Ion Channels; Amino Acid Sequence; Animals; Avoidance Learning; Cerebral Cortex; Conditioning, Classical; Electric Stimulation; Extinction, Psychological; Glutamates; Glycine; Glycogen Synthase Kinase 3 beta; Long-Term Potentiation; Male; Memory; Mice, Inbred C57BL; Peptides; Resorcinols; Signal Transduction; Synaptic Transmission; Taste | 2016 |
Molecular mechanisms of group I metabotropic glutamate receptor mediated LTP and LTD in basolateral amygdala in vitro.
Topics: Animals; Basolateral Nuclear Complex; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; Long-Term Potentiation; Long-Term Synaptic Depression; Male; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols | 2017 |
Association of social defeat stress-induced anhedonia-like symptoms with mGluR1-dependent decrease in membrane-bound AMPA-GluR1 in the mouse ventral midbrain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anhedonia; Animals; Glycine; Male; Mesencephalon; Methoxyhydroxyphenylglycol; Mice; Prefrontal Cortex; Pyridines; Receptors, AMPA; Receptors, Metabotropic Glutamate; Resorcinols; Social Dominance; Stress, Psychological | 2017 |
Presynaptic mGluR5 receptor controls glutamatergic input through protein kinase C-NMDA receptors in paclitaxel-induced neuropathic pain.
Topics: Animals; Antineoplastic Agents, Phytogenic; Behavior, Animal; Cells, Cultured; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Injections, Spinal; Male; Nerve Tissue Proteins; Neuralgia; Neurons, Afferent; Paclitaxel; Protein Kinase C; Protein Kinase Inhibitors; Pyridines; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, N-Methyl-D-Aspartate; Resorcinols; Spinal Cord Dorsal Horn; Synaptosomes | 2017 |
Neuronal Activity-Dependent Activation of Astroglial Calcineurin in Mouse Primary Hippocampal Cultures.
Topics: Animals; Astrocytes; Calcineurin; Calcium; Cell Nucleus; Cells, Cultured; Cytosol; Genetic Vectors; Glycine; Hippocampus; Long-Term Potentiation; Mice, Inbred C57BL; Models, Biological; N-Methylaspartate; Neuroglia; Neurons; Receptor, Metabotropic Glutamate 5; Reproducibility of Results; Resorcinols | 2018 |
Tolerance Induced by (S)-3,5-Dihydroxyphenylglycine Postconditioning is Mediated by the PI3K/Akt/GSK3β Signalling Pathway in an In Vitro Model of Cerebral Ischemia.
Topics: Brain Ischemia; Glycine; Glycogen Synthase Kinase 3 beta; Humans; Methoxyhydroxyphenylglycol; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Resorcinols | 2020 |
Differential mechanisms of tolerance induced by NMDA and 3,5-dihydroxyphenylglycine (DHPG) preconditioning.
Topics: Animals; Cell Hypoxia; Drug Tolerance; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glucose; Glycine; Hippocampus; Ischemic Preconditioning; Male; N-Methylaspartate; Neuroprotection; Organ Culture Techniques; Rats; Rats, Wistar; Receptors, AMPA; Resorcinols | 2020 |
Mechanisms Underlying Enhancement of Spontaneous Glutamate Release by Group I mGluRs at a Central Auditory Synapse.
Topics: Animals; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; Glycine; Male; Mice; Mice, Inbred C57BL; Receptors, Metabotropic Glutamate; Resorcinols; Sodium Channel Blockers; Sound Localization; Synapses; Tetrodotoxin; Trapezoid Body | 2020 |
The selective blockade of metabotropic glutamate receptor-5 attenuates fat accumulation in an in vitro model of benign steatosis.
Topics: Fatty Liver; Glycine; Hep G2 Cells; Humans; PPAR alpha; Pyridines; Receptor, Metabotropic Glutamate 5; Resorcinols; Sterol Regulatory Element Binding Protein 1; Triglycerides | 2020 |
mGlu
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Cognition; Cognitive Dysfunction; Disease Models, Animal; Excitatory Amino Acid Agonists; Female; GABAergic Neurons; Glycine; Interneurons; Male; Memory, Short-Term; Mice, Inbred C57BL; Mice, Transgenic; Neural Inhibition; Prefrontal Cortex; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols; Schizophrenia; Schizophrenic Psychology; Somatostatin | 2021 |