3,5-dihydroxyphenylglycine has been researched along with eglumetad in 8 studies
| Studies (3,5-dihydroxyphenylglycine) | Trials (3,5-dihydroxyphenylglycine) | Recent Studies (post-2010) (3,5-dihydroxyphenylglycine) | Studies (eglumetad) | Trials (eglumetad) | Recent Studies (post-2010) (eglumetad) |
|---|---|---|---|---|---|
| 301 | 1 | 61 | 190 | 5 | 48 |
| 22 | 0 | 10 | 190 | 5 | 48 |
| Protein | Taxonomy | 3,5-dihydroxyphenylglycine (IC50) | eglumetad (IC50) |
|---|---|---|---|
| Metabotropic glutamate receptor 2 | Homo sapiens (human) | 0.0063 | |
| Metabotropic glutamate receptor 3 | Homo sapiens (human) | 0.0279 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (50.00) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Johnson, BG; Monn, JA; Salhoff, CR; Schoepp, DD; Wright, RA | 1 |
| Mathis, C; Ungerer, A | 1 |
| Chamberlain, M; Johnson, MP; Kelly, G | 1 |
| Acher, FC; Brabet, I; Jullian, N; Pin, JP | 1 |
| Costantino, G; Macchiarulo, A; Pellicciari, R | 1 |
| Bräuner-Osborne, H; Egebjerg, J; Krogsgaard-Larsen, P; Madsen, U; Nielsen, EO | 1 |
| Acher, FC; Bertrand, HO; Bessis, AS; Pin, JP | 1 |
| Acher, F; Bertrand, HO; Brabet, I; Pin, JP; Triballeau, N | 1 |
1 review(s) available for 3,5-dihydroxyphenylglycine and eglumetad
| Article | Year |
|---|---|
Ligands for glutamate receptors: design and therapeutic prospects.
Topics: Animals; Drug Design; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Humans; Ligands; N-Methylaspartate; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Synapses | 2000 |
7 other study(ies) available for 3,5-dihydroxyphenylglycine and eglumetad
| Article | Year |
|---|---|
Potent, stereoselective, and brain region selective modulation of second messengers in the rat brain by (+)LY354740, a novel group II metabotropic glutamate receptor agonist.
Topics: Adenosine-5'-(N-ethylcarboxamide); Animals; Brain; Bridged Bicyclo Compounds; Cyclic AMP; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Hydrolysis; Male; Phosphatidylinositols; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols; Second Messenger Systems; Stereoisomerism; Vasodilator Agents | 1998 |
The retention deficit induced by (RS)-alpha-methyl-4-carboxyphenylglycine in a lever-press learning task is blocked by selective agonists of either group I or group II metabotropic glutamate receptors.
Topics: Animals; Benzoates; Bridged Bicyclo Compounds; Cycloleucine; Dose-Response Relationship, Drug; Eating; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Learning; Male; Memory Disorders; Mice; Mice, Inbred Strains; Neuroprotective Agents; Protein Isoforms; Receptors, Metabotropic Glutamate; Resorcinols; Retention, Psychology; Time Factors | 1999 |
Changes in rat serum corticosterone after treatment with metabotropic glutamate receptor agonists or antagonists.
Topics: Adrenalectomy; Adrenocorticotropic Hormone; Amino Acids; Animals; Benzoates; Bridged Bicyclo Compounds; Corticosterone; Cycloleucine; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Male; Neuroprotective Agents; Paraventricular Hypothalamic Nucleus; Phenylacetates; Propionates; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Xanthenes | 2001 |
Agonist selectivity of mGluR1 and mGluR2 metabotropic receptors: a different environment but similar recognition of an extended glutamate conformation.
Topics: Animals; Binding Sites; Cell Line; CHO Cells; Cricetinae; Glutamates; Ligands; Models, Molecular; Molecular Conformation; Receptors, Metabotropic Glutamate; Structure-Activity Relationship | 1999 |
Pharmacophore models of group I and group II metabotropic glutamate receptor agonists. Analysis of conformational, steric, and topological parameters affecting potency and selectivity.
Topics: Excitatory Amino Acid Agonists; Ligands; Molecular Conformation; Receptors, Metabotropic Glutamate; Structure-Activity Relationship | 1999 |
Common and selective molecular determinants involved in metabotopic glutamate receptor agonist activity.
Topics: Binding Sites; Crystallography, X-Ray; Excitatory Amino Acid Agonists; Glutamic Acid; Ligands; Models, Molecular; Receptors, Metabotropic Glutamate; Sequence Homology, Amino Acid; Structure-Activity Relationship | 2002 |
Virtual screening workflow development guided by the "receiver operating characteristic" curve approach. Application to high-throughput docking on metabotropic glutamate receptor subtype 4.
Topics: Binding Sites; Databases, Factual; Drug Design; Models, Molecular; Quantitative Structure-Activity Relationship; Receptors, Metabotropic Glutamate; ROC Curve | 2005 |