Compounds > 3,5-dicarbethoxy-2,6-dimethyl-4-ethyl-1,4-dihydropyridine
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3,5-dicarbethoxy-2,6-dimethyl-4-ethyl-1,4-dihydropyridine and phenobarbital

3,5-dicarbethoxy-2,6-dimethyl-4-ethyl-1,4-dihydropyridine has been researched along with phenobarbital in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19906 (66.67)18.7374
1990's3 (33.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gelboin, HV; Marks, GS; Park, SS; Riddick, DS1
Correia, MA; Lunetta, JM1
De Matteis, F; Lock, EA; Reed, CJ1
Marks, GS; McCluskey, SA; Racz, WJ; Sutherland, EP1
Bornheim, L; Caldera, P; Correia, MA; Decker, C; Rettie, AE; Sugiyama, K; Trager, WF; Wrighton, SA1
Black, KA; Coffman, BL; Dannan, GA; Green, MD; Guengerich, FP; Tephly, TR1
De Matteis, F; Harvey, C; Martin, SR1
Kimmett, SM; Marks, GS; McNamee, JP2

Other Studies

9 other study(ies) available for 3,5-dicarbethoxy-2,6-dimethyl-4-ethyl-1,4-dihydropyridine and phenobarbital

ArticleYear
Effects of 4-alkyl analogues of 3,5-diethoxycarbonyl-1,4-dihydro-2,4,6-trimethylpyridine on hepatic cytochrome P-450 heme, apoproteins, and catalytic activities following in vivo administration to rats.
    Molecular pharmacology, 1990, Volume: 37, Issue:1

    Topics: Animals; Apoproteins; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 Enzyme System; Dexamethasone; Dicarbethoxydihydrocollidine; Dihydropyridines; Enzyme Induction; Heme; Immunologic Techniques; Male; Microsomes, Liver; Phenobarbital; Rats; Structure-Activity Relationship; Time Factors

1990
Acute hepatic heme depletion: impaired gluconeogenesis in rats.
    Seminars in hematology, 1989, Volume: 26, Issue:2

    Topics: Animals; Brain; Dicarbethoxydihydrocollidine; Gluconeogenesis; Glutathione; Glycerol; Heme; Hydroxyindoleacetic Acid; Liver; Phenobarbital; Porphyrias; Rats; Serotonin; Tryptophan; Tryptophan Oxygenase

1989
Olfactory cytochrome P-450. Studies with suicide substrates of the haemoprotein.
    The Biochemical journal, 1988, Jul-15, Volume: 253, Issue:2

    Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Benzoflavones; beta-Naphthoflavone; Cricetinae; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Dicarbethoxydihydrocollidine; Epithelium; Liver; Male; Mesocricetus; NADH Dehydrogenase; Olfactory Mucosa; Oxidoreductases; Oxygenases; Peroxidases; Phenobarbital

1988
Isolation of an N-alkylprotoporphyrin IX from chick embryo livers following the administration of 3,5-diethoxycarbonyl-1,4-dihydro-4-ethyl-2,6-dimethylpyridine.
    Canadian journal of physiology and pharmacology, 1987, Volume: 65, Issue:7

    Topics: Animals; Cells, Cultured; Chick Embryo; Dicarbethoxydihydrocollidine; Dihydropyridines; Ferrochelatase; Kinetics; Liver; Lyases; Phenobarbital; Porphyrins; Protoporphyrins; Spectrophotometry

1987
Degradation of rat hepatic cytochrome P-450 heme by 3,5-dicarbethoxy-2,6-dimethyl-4-ethyl-1,4-dihydropyridine to irreversibly bound protein adducts.
    Archives of biochemistry and biophysics, 1987, Nov-01, Volume: 258, Issue:2

    Topics: Animals; Cytochrome P-450 Enzyme System; Dexamethasone; Dicarbethoxydihydrocollidine; Dihydropyridines; Heme; Kinetics; Male; Microsomes, Liver; Phenobarbital; Protein Binding; Rats; Rats, Inbred Strains

1987
Effect of suicide substrate on the metabolism of steroids and xenobiotics and on cytochrome P-450 apoproteins.
    Advances in experimental medicine and biology, 1986, Volume: 197

    Topics: Aminopyrine; Animals; Apoproteins; Carbon Radioisotopes; Cytochrome P-450 Enzyme System; Dicarbethoxydihydrocollidine; Formaldehyde; Formates; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Morphine; Phenobarbital; Pyridines; Rats; Rats, Inbred Strains; Testosterone

1986
N-alkylation of exogenous haem analogues caused by drugs in isolated hepatocytes. Structural isomerism and chirality of the resulting porphyrins.
    The Biochemical journal, 1986, Aug-15, Volume: 238, Issue:1

    Topics: Acetamides; Allylisopropylacetamide; Animals; Benzoflavones; beta-Naphthoflavone; Chromatography, High Pressure Liquid; Deuteroporphyrins; Dicarbethoxydihydrocollidine; In Vitro Techniques; Liver; Male; Mesoporphyrins; Phenobarbital; Porphyrins; Pyridines; Rats; Rats, Inbred Strains; Stereoisomerism

1986
Inactivation of chick embryo hepatic cytochrome P450 1A, 2H and 3A following in ovo administration of 3,5-diethoxycarbonyl-1,4-dihydro-2,6-dimethyl-4-ethylpyridine and 3-[2-(2,4,6-trimethylphenyl)thioethyl]-4-methylsydnone.
    Biochemical pharmacology, 1995, May-17, Volume: 49, Issue:10

    Topics: Alkylation; Animals; Aryl Hydrocarbon Hydroxylases; Chick Embryo; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dexamethasone; Dicarbethoxydihydrocollidine; Glutethimide; In Vitro Techniques; Liver; Microsomes, Liver; Oxidoreductases; Oxidoreductases, N-Demethylating; Phenobarbital; Rats; Sydnones

1995
Mechanism-based inactivation of hepatic cytochrome P450 2C6 and P450 3A1 following in vivo administration of 3,5-diethoxycarbonyl-1,4-dihydro-2,6-dimethyl-4-ethylpyridine to rats: differences from previously observed in vitro results.
    Canadian journal of physiology and pharmacology, 1994, Volume: 72, Issue:4

    Topics: Animals; Chromatography, Thin Layer; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P450 Family 2; Dexamethasone; Dicarbethoxydihydrocollidine; Female; In Vitro Techniques; Liver; Male; Microsomes, Liver; Phenobarbital; Rats; Steroid 21-Hydroxylase; Steroid Hydroxylases

1994