3-5-dibromo-2-pyrone and pancratistatin

3-5-dibromo-2-pyrone has been researched along with pancratistatin* in 2 studies

Other Studies

2 other study(ies) available for 3-5-dibromo-2-pyrone and pancratistatin

ArticleYear
(E)-β-borylstyrene in the Diels-Alder reaction with 3,5-dibromo-2-pyrone for the syntheses of (±)-1-epi-pancratistatin and (±)- pancratistatin.
    Organic letters, 2013, Nov-15, Volume: 15, Issue:22

    New synthetic routes to (±)-1-epi-pancratistatin and (±)-pancratistatin were devised using (E)-β-borylstyrene as a dienophile for the key Diels-Alder reaction with 3,5-dibromo-2-pyrone. The boronate in the cycloadduct was oxidized to provide the pivotal C1-hydroxyl group of the titled compounds.

    Topics: Amaryllidaceae Alkaloids; Cycloaddition Reaction; Isoquinolines; Molecular Structure; Oxidation-Reduction; Pyrones

2013
β-Silyl styrene as a dienophile in the cycloaddition with 3,5-dibromo-2-pyrone for the total synthesis of (±)-pancratistatin.
    Organic letters, 2011, Nov-04, Volume: 13, Issue:21

    A new synthetic route to (±)-pancratistatin was devised utilizing β-silyl styrene as a dienophile in the cycloaddition with 3,5-dibromo-2-pyrone. The TMS group incorporated in the cycloadduct permitted a facile elimination process for the eventual installation of the C(1)-OH function. Subsequent transformations including Curtius rearrangement and Bischler-Napieralski reactions completed the total synthesis of (±)-pancratistatin.

    Topics: Amaryllidaceae Alkaloids; Cyclization; Isoquinolines; Molecular Structure; Pyrones; Silicon; Styrene

2011