3-5-dibromo-2-pyrone has been researched along with pancratistatin* in 2 studies
2 other study(ies) available for 3-5-dibromo-2-pyrone and pancratistatin
Article | Year |
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(E)-β-borylstyrene in the Diels-Alder reaction with 3,5-dibromo-2-pyrone for the syntheses of (±)-1-epi-pancratistatin and (±)- pancratistatin.
New synthetic routes to (±)-1-epi-pancratistatin and (±)-pancratistatin were devised using (E)-β-borylstyrene as a dienophile for the key Diels-Alder reaction with 3,5-dibromo-2-pyrone. The boronate in the cycloadduct was oxidized to provide the pivotal C1-hydroxyl group of the titled compounds. Topics: Amaryllidaceae Alkaloids; Cycloaddition Reaction; Isoquinolines; Molecular Structure; Oxidation-Reduction; Pyrones | 2013 |
β-Silyl styrene as a dienophile in the cycloaddition with 3,5-dibromo-2-pyrone for the total synthesis of (±)-pancratistatin.
A new synthetic route to (±)-pancratistatin was devised utilizing β-silyl styrene as a dienophile in the cycloaddition with 3,5-dibromo-2-pyrone. The TMS group incorporated in the cycloadduct permitted a facile elimination process for the eventual installation of the C(1)-OH function. Subsequent transformations including Curtius rearrangement and Bischler-Napieralski reactions completed the total synthesis of (±)-pancratistatin. Topics: Amaryllidaceae Alkaloids; Cyclization; Isoquinolines; Molecular Structure; Pyrones; Silicon; Styrene | 2011 |