Compounds > 3,5-bis(trifluoromethyl)benzyl n-acetyltryptophan
Page last updated: 2024-09-03

3,5-bis(trifluoromethyl)benzyl n-acetyltryptophan and sr 48968

3,5-bis(trifluoromethyl)benzyl n-acetyltryptophan has been researched along with sr 48968 in 5 studies

Compound Research Comparison

Studies
(3,5-bis(trifluoromethyl)benzyl n-acetyltryptophan)		Trials
(3,5-bis(trifluoromethyl)benzyl n-acetyltryptophan)		Recent Studies (post-2010)
(3,5-bis(trifluoromethyl)benzyl n-acetyltryptophan)		Studies
(sr 48968)		Trials
(sr 48968)		Recent Studies (post-2010) (sr 48968)
75024338213

Protein Interaction Comparison

ProteinTaxonomy3,5-bis(trifluoromethyl)benzyl n-acetyltryptophan (IC50)sr 48968 (IC50)
Substance-K receptorHomo sapiens (human)0.0001
Substance-P receptorHomo sapiens (human)0.8

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's2 (40.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cascieri, MA; MaCcoss, M; Qi, H; Sadowski, SJ; Shah, SK1
El-Mahmoudy, A; Khalifa, M; Matsuyama, H; Shimizu, Y; Takewaki, T1
Hayes, D; Lee, LY; Lin, RL1
Hayashi, H; Oh-ishi, T; Onaga, T; Shimoda, T1
Hsu, CC; Lee, LY; Tapia, RJ1

Other Studies

5 other study(ies) available for 3,5-bis(trifluoromethyl)benzyl n-acetyltryptophan and sr 48968

ArticleYear
L-tryptophan urea amides as NK1/NK2 dual antagonists.
    Bioorganic & medicinal chemistry letters, 1998, Aug-18, Volume: 8, Issue:16

    Topics: Amides; Drug Design; Humans; Indicators and Reagents; Kinetics; Molecular Structure; Neurokinin-1 Receptor Antagonists; Receptors, Neurokinin-2; Recombinant Proteins; Structure-Activity Relationship; Tryptophan

1998
Tachykinins mediate non-adrenergic, non-cholinergic excitatory neurotransmission to the hamster ileum via NK1 and NK2 receptors.
    Life sciences, 2003, Aug-29, Volume: 73, Issue:15

    Topics: Animals; Autonomic Agents; Benzamides; Cricetinae; Dose-Response Relationship, Drug; Electric Stimulation; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neurokinin-1 Receptor Antagonists; Neuromuscular Junction; NG-Nitroarginine Methyl Ester; Piperidines; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P; Synaptic Transmission; Tryptophan

2003
Bronchoconstriction induced by hyperventilation with humidified hot air: role of TRPV1-expressing airway afferents.
    Journal of applied physiology (Bethesda, Md. : 1985), 2009, Volume: 106, Issue:6

    Topics: Airway Resistance; Animals; Atropine; Benzamides; Bronchoconstriction; Bronchodilator Agents; Capsaicin; Disease Models, Animal; Drug Combinations; Ethanolamines; Formoterol Fumarate; Guinea Pigs; Hot Temperature; Humidity; Hyperthermia, Induced; Hyperventilation; Male; Neurons, Afferent; Piperidines; Receptors, Tachykinin; Specific Pathogen-Free Organisms; TRPV Cation Channels; Tryptophan

2009
Role of tachykinins and neurokinin receptor subtypes in the regulation of motility of the forestomach and abomasum in conscious sheep.
    Neuropeptides, 2013, Volume: 47, Issue:1

    Topics: Abomasum; Animals; Benzamides; Gastrointestinal Motility; Injections, Intravenous; Kinetics; Male; Muscle Contraction; Neurokinin A; Omasum; Piperidines; Receptors, Neurokinin-2; Rumen; Sheep; Substance P; Tachykinins; Tryptophan

2013
Airway extravasation induced by increasing airway temperature in ovalbumin-sensitized rats.
    Respiratory physiology & neurobiology, 2015, Volume: 212-214

    Topics: Airway Resistance; Analysis of Variance; Animals; Benzamides; Bronchoalveolar Lavage Fluid; Bronchodilator Agents; Evans Blue; Formoterol Fumarate; Hot Temperature; Male; Ovalbumin; Piperidines; Rats; Respiratory Hypersensitivity; Trachea; Tryptophan

2015