3,5-bis(trifluoromethyl)benzyl n-acetyltryptophan has been researched along with morphine in 3 studies
| Studies (3,5-bis(trifluoromethyl)benzyl n-acetyltryptophan) | Trials (3,5-bis(trifluoromethyl)benzyl n-acetyltryptophan) | Recent Studies (post-2010) (3,5-bis(trifluoromethyl)benzyl n-acetyltryptophan) | Studies (morphine) | Trials (morphine) | Recent Studies (post-2010) (morphine) |
|---|---|---|---|---|---|
| 75 | 0 | 24 | 44,270 | 5,200 | 8,695 |
| Protein | Taxonomy | 3,5-bis(trifluoromethyl)benzyl n-acetyltryptophan (IC50) | morphine (IC50) |
|---|---|---|---|
| Delta-type opioid receptor | Mus musculus (house mouse) | 0.2939 | |
| Delta-type opioid receptor | Rattus norvegicus (Norway rat) | 0.2278 | |
| Kappa-type opioid receptor | Mus musculus (house mouse) | 0.0828 | |
| Mu-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0385 | |
| Kappa-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0545 | |
| Mu-type opioid receptor | Homo sapiens (human) | 0.122 | |
| Delta-type opioid receptor | Homo sapiens (human) | 0.1199 | |
| Kappa-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.9308 | |
| Kappa-type opioid receptor | Homo sapiens (human) | 0.655 | |
| Mu-type opioid receptor | Mus musculus (house mouse) | 0.3305 | |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.202 | |
| Beta-2 adrenergic receptor | Cavia porcellus (domestic guinea pig) | 0.25 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Davis, P; Hruby, VJ; Jacobsen, NE; Lai, J; Largent-Milnes, TM; Ma, SW; Nair, P; Porreca, F; Vanderah, TW; Yamamoto, T; Yamamura, HI | 1 |
| Gardell, LR; Hruby, VJ; Hunt, SP; King, T; Lai, J; Malan, PT; Ossipov, MH; Porreca, F; Vanderah, TW; Vardanyan, A; Wang, R | 1 |
| Hruby, VJ; Keresztes, AI; Largent-Milnes, TM; Roeske, WR; Tumati, S; Vanderah, TW; Varga, EV; Yamamoto, T | 1 |
3 other study(ies) available for 3,5-bis(trifluoromethyl)benzyl n-acetyltryptophan and morphine
| Article | Year |
|---|---|
Discovery of a potent and efficacious peptide derivative for δ/μ opioid agonist/neurokinin 1 antagonist activity with a 2',6'-dimethyl-L-tyrosine: in vitro, in vivo, and NMR-based structural studies.
Topics: Amino Acid Sequence; Analgesics; Animals; Drug Discovery; Drug Stability; Guanosine 5'-O-(3-Thiotriphosphate); Guinea Pigs; Humans; Ileum; Magnetic Resonance Spectroscopy; Male; Mice; Micelles; Molecular Conformation; Neurokinin-1 Receptor Antagonists; Peptides; Rats; Receptors, Neurokinin-1; Receptors, Opioid, mu; Receptors, sigma; Structure-Activity Relationship; Tyrosine; Vas Deferens | 2011 |
Role of NK-1 neurotransmission in opioid-induced hyperalgesia.
Topics: Animals; Cell Count; Drug Interactions; Hot Temperature; Hyperalgesia; Immunohistochemistry; Male; Mice; Mice, Knockout; Morphine; Narcotics; Neurokinin-1 Receptor Antagonists; Pain Measurement; Protein Transport; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Neurokinin-1; Spinal Cord; Substance P; Synaptic Transmission; Time Factors; Touch; Tryptophan | 2005 |
Tachykinin NK₁ receptor antagonist co-administration attenuates opioid withdrawal-mediated spinal microglia and astrocyte activation.
Topics: Analgesics, Opioid; Animals; Astrocytes; Biomarkers; CD11b Antigen; Hyperalgesia; Male; Microglia; Morphine; Nerve Tissue Proteins; Neurokinin-1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance Withdrawal Syndrome; Tryptophan; Tumor Necrosis Factor-alpha; Up-Regulation | 2012 |