3,5-bis(acetoxyacetylamino)-4-chlorobenzonitrile has been researched along with histamine in 3 studies
*Histamine: An amine derived by enzymatic decarboxylation of HISTIDINE. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter. [MeSH]
*Histamine: An amine derived by enzymatic decarboxylation of HISTIDINE. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter. [MeSH]
| Studies (3,5-bis(acetoxyacetylamino)-4-chlorobenzonitrile) | Trials (3,5-bis(acetoxyacetylamino)-4-chlorobenzonitrile) | Recent Studies (post-2010) (3,5-bis(acetoxyacetylamino)-4-chlorobenzonitrile) | Studies (histamine) | Trials (histamine) | Recent Studies (post-2010) (histamine) |
|---|---|---|---|---|---|
| 23 | 0 | 8 | 37,718 | 1,372 | 3,457 |
| Protein | Taxonomy | 3,5-bis(acetoxyacetylamino)-4-chlorobenzonitrile (IC50) | histamine (IC50) |
|---|---|---|---|
| Histamine H1 receptor | Rattus norvegicus (Norway rat) | 0.1585 | |
| Histamine H1 receptor | Homo sapiens (human) | 0.1585 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Muraki, M; Nagasaka, Y; Nakajima, S; Sugihara, R; Tohda, Y | 1 |
| Abraham, WM; Ahmed, A; Cortes, A; Sielczak, M; Wantanabe, A | 1 |
| Hayashi, H; Koda, A; Kumazawa, Y; Nagai, H; Shimada, H; Shutoh, H; Tominaga, T; Tsuji, J; Watanabe, A | 1 |
3 other study(ies) available for 3,5-bis(acetoxyacetylamino)-4-chlorobenzonitrile and histamine
| Article | Year |
|---|---|
The effect of TYB-2285 on dual phase bronchoconstriction and airway hypersensitivity in guinea-pigs actively sensitized with ovalbumin.
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Calcimycin; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Luminescent Measurements; Luminol; Male; Nitriles; Ovalbumin; Respiratory Function Tests; Respiratory Hypersensitivity | 1994 |
Effect of TYB-2285 on antigen-induced airway responses in sheep.
Topics: Animals; Asthma; Bronchi; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Cross-Over Studies; Eosinophils; Histamine; Leukotriene D4; Nitriles; Sheep; Trachea | 1996 |
Effect of TYB-2285 on passive cutaneous anaphylaxis in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antigens, Helminth; Ascaris suum; Capillary Permeability; Dinitrobenzenes; Dose-Response Relationship, Drug; Histamine; Male; Nitriles; Ovalbumin; Passive Cutaneous Anaphylaxis; Rats; Time Factors | 1997 |