3,4-methylenedioxyamphetamine and piperidines

3,4-methylenedioxyamphetamine has been researched along with piperidines in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19905 (20.00)18.7374
1990's17 (68.00)18.2507
2000's2 (8.00)29.6817
2010's1 (4.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fadayel, GM; Schmidt, CJ; Sullivan, CK; Taylor, VL1
Katz, JL; Martello, AL; Martello, MB; Ricaurte, GA1
Culp, S; DeSouza, EB; Lehmann, J; Zaczek, R1
Black, CK; Fadayel, GM; Humphreys, TM; Nieduzak, TR; Schmidt, CJ; Sorensen, SM; Taylor, VL1
Colpaert, FC; Millan, MJ1
Battaglia, G; de Souza, EB; Kuhar, MJ; Sharkey, J1
Kelly, PA; McBean, DE; Sharkey, J1
Goromaru, T; Hashimoto, K1
Arora, RC; Meltzer, HY; Nash, JF; Schreiber, MA1
Guan, XM; McKenna, DJ; Shulgin, AT1
Abbate, GM; Nieduzak, TR; Schmidt, CJ; Taylor, VL1
Brewster, WK; Johnson, MP; Nichols, DE; Oberlender, R; Riggs, RM1
Hekmatpanah, CR; Peroutka, SJ1
Peroutka, SJ; Wagner, J1
Ricaurte, GA; Scheffel, U1
Abbate, GM; Black, CK; Schmidt, CJ; Taylor, VL1
Battaglia, G; De Souza, EB; Kuhar, MJ; Molliver, ME; O'Hearn, E; Yeh, SY1
Johnson, MP; Nichols, DE1
Hekmatpanah, CR; McKenna, DJ; Peroutka, SJ1
Glennon, RA; Rosecrans, JA1
Gibb, JW; Hanson, GR; Johnson, M1
Fadayel, GM; Schmidt, CJ; Sullivan, CK1
Colado, MI; Elliott, JM; Esteban, B; Green, AR; Mechan, AO; O'Shea, E1
Baker, GB; Fletcher, PJ; Korth, KM; Robinson, SR1
Dinger, J; Maurer, HH; Meyer, MR1

Other Studies

25 other study(ies) available for 3,4-methylenedioxyamphetamine and piperidines

ArticleYear
5-HT2 receptors exert a state-dependent regulation of dopaminergic function: studies with MDL 100,907 and the amphetamine analogue, 3,4-methylenedioxymethamphetamine.
    European journal of pharmacology, 1992, Nov-13, Volume: 223, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; 3,4-Methylenedioxyamphetamine; Animals; Brain Chemistry; Dialysis; Dopamine; Fluorobenzenes; Haloperidol; Homovanillic Acid; Male; N-Methyl-3,4-methylenedioxyamphetamine; Piperidines; Rats; Rats, Sprague-Dawley; Reserpine; Serotonin Antagonists

1992
Lasting effects of (+-)-3,4-methylenedioxymethamphetamine (MDMA) on central serotonergic neurons in nonhuman primates: neurochemical observations.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 261, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; 3,4-Methylenedioxyamphetamine; Animals; Brain; Cell Membrane; Chromatography, High Pressure Liquid; Dopamine; Female; Hydroxyindoleacetic Acid; Injections, Subcutaneous; Male; N-Methyl-3,4-methylenedioxyamphetamine; Neurons; Norepinephrine; Paroxetine; Piperidines; Saimiri; Serotonin; Serotonin Antagonists

1992
Regional distribution to recovery of 5-HT levels after administration of "atrophins" MDMA and D,L-fenfluramine. Stereospecificity and comparison with 5,7-dihydroxytryptamine.
    Annals of the New York Academy of Sciences, 1992, May-11, Volume: 648

    Topics: 3,4-Dihydroxyphenylacetic Acid; 3,4-Methylenedioxyamphetamine; 5,7-Dihydroxytryptamine; Animals; Atrophy; Brain; Cerebral Ventricles; Designer Drugs; Dopamine; Fenfluramine; Homovanillic Acid; Hydroxyindoleacetic Acid; Injections, Intraventricular; Male; N-Methyl-3,4-methylenedioxyamphetamine; Norepinephrine; Organ Specificity; Paroxetine; Piperidines; Rats; Rats, Inbred Strains; Serotonin; Stereoisomerism

1992
The 5-HT2 receptor antagonist, MDL 28,133A, disrupts the serotonergic-dopaminergic interaction mediating the neurochemical effects of 3,4-methylenedioxymethamphetamine.
    European journal of pharmacology, 1992, Sep-22, Volume: 220, Issue:2-3

    Topics: 3,4-Methylenedioxyamphetamine; alpha-Methyltyrosine; Animals; Brain; Corpus Striatum; Dopamine; Electrophysiology; Levodopa; Male; Methyltyrosines; Neurons; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Serotonin Antagonists

1992
Methylenedioxymethamphetamine induces spontaneous tail-flicks in the rat via 5-HT1A receptors.
    European journal of pharmacology, 1991, Feb-07, Volume: 193, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Dopamine Antagonists; Dose-Response Relationship, Drug; Male; N-Methyl-3,4-methylenedioxyamphetamine; Paroxetine; Piperidines; Rats; Rats, Inbred Strains; Reflex; Serotonin; Serotonin Antagonists; Tail

1991
Neuroanatomic specificity and time course of alterations in rat brain serotonergic pathways induced by MDMA (3,4-methylenedioxymethamphetamine): assessment using quantitative autoradiography.
    Synapse (New York, N.Y.), 1991, Volume: 8, Issue:4

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Autoradiography; Brain; Dopamine; Male; Mazindol; N-Methyl-3,4-methylenedioxyamphetamine; Neural Pathways; Norepinephrine; Paroxetine; Piperidines; Rats; Rats, Inbred Strains; Reference Values; Serotonin; Time Factors

1991
Alterations in hippocampal function following repeated exposure to the amphetamine derivative methylenedioxymethamphetamine ("Ecstasy").
    Psychopharmacology, 1991, Volume: 105, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Autoradiography; Brain Chemistry; Cerebral Cortex; Deoxyglucose; Glucose; Hippocampus; Male; N-Methyl-3,4-methylenedioxyamphetamine; Paroxetine; Piperidines; Pyramidal Tracts; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists

1991
Reduction of in vivo binding of [3H]paroxetine in mouse brain by 3,4-methylenedioxymethamphetamine.
    Neuropharmacology, 1990, Volume: 29, Issue:7

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Analysis of Variance; Animals; Brain; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Hydroxyindoleacetic Acid; Injections, Intravenous; Male; Mice; N-Methyl-3,4-methylenedioxyamphetamine; Paroxetine; Piperidines; Serotonin; Serotonin Antagonists

1990
Effect of 3,4-methylenedioxymethamphetamine on [3H]paroxetine binding in the frontal cortex and blood platelets of rats.
    Biochemical pharmacology, 1991, Jan-01, Volume: 41, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Blood Platelets; Frontal Lobe; Hydroxyindoleacetic Acid; Ketanserin; Kinetics; Male; N-Methyl-3,4-methylenedioxyamphetamine; Paroxetine; Piperidines; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists; Time Factors; Tritium

1991
3,4-Methylenedioxyamphetamine (MDA) analogues exhibit differential effects on synaptosomal release of 3H-dopamine and 3H-5-hydroxytryptamine.
    Pharmacology, biochemistry, and behavior, 1991, Volume: 38, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Dopamine; In Vitro Techniques; Male; Molecular Structure; Nervous System; Paroxetine; Piperidines; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists; Structure-Activity Relationship; Synaptosomes; Tritium

1991
5-HT2 antagonists stereoselectively prevent the neurotoxicity of 3,4-methylenedioxymethamphetamine by blocking the acute stimulation of dopamine synthesis: reversal by L-dopa.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 256, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; 3,4-Methylenedioxyamphetamine; Animals; Anti-Arrhythmia Agents; Brain; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Drug Synergism; Haloperidol; Homovanillic Acid; Levodopa; Male; Nomifensine; Piperidines; Rats; Rats, Inbred Strains; Ritanserin; Serotonin Antagonists; Stereoisomerism; Time Factors

1991
Nonneurotoxic tetralin and indan analogues of 3,4-(methylenedioxy)amphetamine (MDA).
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Behavior, Animal; Catecholamines; Cerebral Cortex; Hippocampus; Indans; Lysergic Acid Diethylamide; N-Methyl-3,4-methylenedioxyamphetamine; Paroxetine; Piperidines; Psychotropic Drugs; Rats; Serotonin; Structure-Activity Relationship; Tetrahydronaphthalenes

1990
5-hydroxytryptamine uptake blockers attenuate the 5-hydroxytryptamine-releasing effect of 3,4-methylenedioxymethamphetamine and related agents.
    European journal of pharmacology, 1990, Feb-20, Volume: 177, Issue:1-2

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Brain Chemistry; In Vitro Techniques; Male; N-Methyl-3,4-methylenedioxyamphetamine; Paroxetine; Piperidines; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists; Synaptosomes

1990
Neurochemistry and neurotoxicity of substituted amphetamines.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1990, Volume: 3, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Designer Drugs; Fenfluramine; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Endings; Paroxetine; Piperidines; Rats; Receptors, Serotonin; Serotonin

1990
Paroxetine as an in vivo indicator of 3,4-methylenedioxymethamphetamine neurotoxicity: a presynaptic serotonergic positron emission tomography ligand?
    Brain research, 1990, Sep-10, Volume: 527, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; 5,7-Dihydroxytryptamine; Animals; Ligands; Male; N-Methyl-3,4-methylenedioxyamphetamine; Nervous System; Paroxetine; Piperidines; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists; Synapses; Tomography, Emission-Computed; Tritium

1990
Methylenedioxymethamphetamine-induced hyperthermia and neurotoxicity are independently mediated by 5-HT2 receptors.
    Brain research, 1990, Oct-08, Volume: 529, Issue:1-2

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Body Temperature; Cerebral Cortex; Corpus Striatum; Haloperidol; Hippocampus; Male; N-Methyl-3,4-methylenedioxyamphetamine; Neurotoxins; Piperidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Reference Values; Serotonin; Serotonin Antagonists

1990
3,4-Methylenedioxymethamphetamine and 3,4-methylenedioxyamphetamine destroy serotonin terminals in rat brain: quantification of neurodegeneration by measurement of [3H]paroxetine-labeled serotonin uptake sites.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 242, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Brain; Brain Chemistry; Dopamine; Hydroxyindoleacetic Acid; Male; N-Methyl-3,4-methylenedioxyamphetamine; Paroxetine; Piperidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Tritium

1987
Neurotoxic effects of the alpha-ethyl homologue of MDMA following subacute administration.
    Pharmacology, biochemistry, and behavior, 1989, Volume: 33, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Biogenic Monoamines; Brain Chemistry; Hydroxyindoleacetic Acid; Male; N-Methyl-3,4-methylenedioxyamphetamine; Nervous System Diseases; Norepinephrine; Paroxetine; Piperidines; Rats; Rats, Inbred Strains; Serotonin

1989
Reserpine does not prevent 3,4-methylenedioxymethamphetamine-induced neurotoxicity in the rat.
    Neuroscience letters, 1989, Sep-25, Volume: 104, Issue:1-2

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Cerebral Cortex; Corpus Striatum; Designer Drugs; Dopamine; Male; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Endings; Nervous System Diseases; Paroxetine; Piperidines; Rats; Rats, Inbred Strains; Reserpine; Serotonin

1989
The effect of MDA and MDMA ("Ecstasy") isomers in combination with pirenpirone on operant responding in mice.
    Pharmacology, biochemistry, and behavior, 1987, Volume: 28, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Conditioning, Operant; Drug Combinations; Isomerism; Mice; N-Methyl-3,4-methylenedioxyamphetamine; Piperidines; Serotonin Antagonists

1987
Effects of dopaminergic and serotonergic receptor blockade on neurochemical changes induced by acute administration of methamphetamine and 3,4-methylenedioxymethamphetamine.
    Neuropharmacology, 1988, Volume: 27, Issue:11

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Haloperidol; Male; Methamphetamine; Methiothepin; Piperidines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Serotonin; Ritanserin; Serotonin Antagonists

1988
Blockade of striatal 5-hydroxytryptamine2 receptors reduces the increase in extracellular concentrations of dopamine produced by the amphetamine analogue 3,4-methylenedioxymethamphetamine.
    Journal of neurochemistry, 1994, Volume: 62, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; 3,4-Methylenedioxyamphetamine; Animals; Corpus Striatum; Dialysis; Dopamine; Extracellular Space; Fluorobenzenes; Homovanillic Acid; Kinetics; N-Methyl-3,4-methylenedioxyamphetamine; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Antagonists; Tetrodotoxin

1994
The pharmacology of the acute hyperthermic response that follows administration of 3,4-methylenedioxymethamphetamine (MDMA, 'ecstasy') to rats.
    British journal of pharmacology, 2002, Volume: 135, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Acute Disease; Animals; Benzazepines; Body Temperature; Corpus Striatum; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Fever; Hallucinogens; Hippocampus; Male; Methysergide; N-Methyl-3,4-methylenedioxyamphetamine; Neuroprotective Agents; Piperazines; Piperidines; Rats; Rats, Inbred Strains; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Remoxipride; Ritanserin; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists

2002
Multiple 5-HT receptors are involved in the effects of acute MDMA treatment: studies on locomotor activity and responding for conditioned reinforcement.
    Psychopharmacology, 2002, Volume: 162, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Conditioning, Operant; Dose-Response Relationship, Drug; Ethylamines; Indoles; Ketanserin; Male; Motor Activity; Oxadiazoles; Piperazines; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Reinforcement, Psychology; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists; Time Factors

2002
In vitro cytochrome P450 inhibition potential of methylenedioxy-derived designer drugs studied with a two-cocktail approach.
    Archives of toxicology, 2016, Volume: 90, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Designer Drugs; Drug Interactions; Humans; Inhibitory Concentration 50; Microsomes, Liver; Piperidines; Toxicity Tests

2016