3,4-methylenedioxyamphetamine and n-methyl-1-(1,3-benzodioxol-5-yl)-2-butanamine

3,4-methylenedioxyamphetamine has been researched along with n-methyl-1-(1,3-benzodioxol-5-yl)-2-butanamine in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19904 (12.90)18.7374
1990's12 (38.71)18.2507
2000's13 (41.94)29.6817
2010's2 (6.45)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hoffman, AJ; Jacob, P; Nichols, DE; Oberlender, RA; Shulgin, AT1
Cozzi, NV; Marona-Lewicka, D; Monte, AP; Nichols, DE1
Kurrasch, D; Marona-Lewicka, D; Nichols, DE; Parker, MA; Shulgin, AT1
Clare, BW1
Callaway, CW; Geyer, MA1
Callaway, CW; Geyer, MA; Gold, LH; Johnson, MP; Nichols, DE1
Nichols, DE; Oberlender, R1
Johnson, MP; Nichols, DE1
Dimpfel, W; Nichols, DE; Spüler, M1
Nichols, DE; Steele, TD; Yim, GK1
Marona-Lewicka, D; Nichols, DE2
Marona-Lewicka, D; Nichols, DE; Rhee, GS; Sprague, JE1
Kronstrand, R1
Brownfield, MS; Levy, AD; Li, Q; Murakami, I; Nichols, DE; Stall, S; Van de Kar, LD1
Sadeghipour, F; Veuthey, JL1
Dulawa, SC; Geyer, MA; Hen, R; Scearce-Levie, KA1
Carter, N; Forrest, AR; Milroy, CM; Rutty, GN1
Kurosu, A; Kuroyanagi, K; Matsushima, K; Nagai, T; Nihei, H; Saotome, A; Suzuki, A; Tokudome, S1
Kovar, KA; Mayerhofer, A; Meyer, A; Schmidt, WJ1
Kovar, KA; Lebsanft, HB; Mayerhofer, A; Schmidt, WJ1
Concheiro, M; Cruz, A; de Castro, A; López-Rivadulla, M; Quintela, O1
Corkery, J; Deluca, P; Ghodse, AH; Oyefeso, A; Schifano, F1
Goda, Y; Kawamura, M; Kikura-Hanajiri, R; Kodama, Y; Saisho, K1
Chèze, M; Deveaux, M; Lhermitte, M; Martin, C; Pépin, G1
Ishii, H; Nakagawa, Y; Ogata, A; Suzuki, T; Tayama, S1
Kamata, HT; Kamata, T; Katagi, M; Miki, A; Mori, Y; Shima, N; Tsuchihashi, H; Zaitsu, K1
Maurer, HH; Meyer, MR; Peters, FT2
Awad, T; Belal, T; Clark, CR; DeRuiter, J; Maher, HM1
Covaci, A; Erratico, C; Kinyua, J; Lai, FY; Mueller, JF; van Nuijs, AL1

Other Studies

31 other study(ies) available for 3,4-methylenedioxyamphetamine and n-methyl-1-(1,3-benzodioxol-5-yl)-2-butanamine

ArticleYear
Derivatives of 1-(1,3-benzodioxol-5-yl)-2-butanamine: representatives of a novel therapeutic class.
    Journal of medicinal chemistry, 1986, Volume: 29, Issue:10

    Topics: Adult; Animals; Butylamines; Dioxoles; Discrimination Learning; Female; Generalization, Stimulus; Hallucinogens; Humans; Lysergic Acid Diethylamide; Male; Middle Aged; Psychotropic Drugs; Rats; Rats, Inbred Strains; Structure-Activity Relationship

1986
Synthesis and pharmacological examination of benzofuran, indan, and tetralin analogues of 3,4-(methylenedioxy)amphetamine.
    Journal of medicinal chemistry, 1993, Nov-12, Volume: 36, Issue:23

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Benzofurans; Brain; Discrimination Learning; Dopamine; Indenes; Male; Molecular Structure; Norepinephrine; Rats; Rats, Sprague-Dawley; Serotonin; Structure-Activity Relationship; Synaptosomes; Tetrahydronaphthalenes

1993
Synthesis and pharmacological evaluation of ring-methylated derivatives of 3,4-(methylenedioxy)amphetamine (MDA).
    Journal of medicinal chemistry, 1998, Mar-12, Volume: 41, Issue:6

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Antidepressive Agents; Behavior, Animal; Brain; Dioxoles; In Vitro Techniques; Male; Rats; Rats, Sprague-Dawley; Serotonin Agents; Synaptosomes

1998
The frontier orbital phase angles: novel QSAR descriptors for benzene derivatives, applied to phenylalkylamine hallucinogens.
    Journal of medicinal chemistry, 1998, Sep-24, Volume: 41, Issue:20

    Topics: Hallucinogens; Humans; Models, Molecular; Molecular Conformation; Phenethylamines; Quantum Theory

1998
Stimulant effects of 3,4-methylenedioxymethamphetamine in the nucleus accumbens of rat.
    European journal of pharmacology, 1992, Apr-07, Volume: 214, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamine; Animals; Behavior, Animal; Corpus Striatum; Fluoxetine; Male; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Nucleus Accumbens; Rats; Rats, Inbred Strains

1992
Amphetamine derivatives induce locomotor hyperactivity by acting as indirect serotonin agonists.
    Psychopharmacology, 1991, Volume: 104, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Biogenic Amines; Brain Chemistry; Dose-Response Relationship, Drug; Exploratory Behavior; Fluoxetine; Male; Motor Activity; p-Chloroamphetamine; Rats; Rats, Inbred Strains; Serotonin

1991
(+)-N-methyl-1-(1,3-benzodioxol-5-yl)-2-butanamine as a discriminative stimulus in studies of 3,4-methylenedioxy-methamphetamine-like behavioral activity.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 255, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Hallucinogens; Indans; Learning; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Stereoisomerism

1990
Neurotoxic effects of the alpha-ethyl homologue of MDMA following subacute administration.
    Pharmacology, biochemistry, and behavior, 1989, Volume: 33, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Biogenic Monoamines; Brain Chemistry; Hydroxyindoleacetic Acid; Male; N-Methyl-3,4-methylenedioxyamphetamine; Nervous System Diseases; Norepinephrine; Paroxetine; Piperidines; Rats; Rats, Inbred Strains; Serotonin

1989
Hallucinogenic and stimulatory amphetamine derivatives: fingerprinting DOM, DOI, DOB, MDMA, and MBDB by spectral analysis of brain field potentials in the freely moving rat (Tele-Stereo-EEG).
    Psychopharmacology, 1989, Volume: 98, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Brain; Central Nervous System Stimulants; DOM 2,5-Dimethoxy-4-Methylamphetamine; Electroencephalography; Evoked Potentials; Hallucinogens; Injections, Intraperitoneal; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred F344; Telemetry

1989
Stereochemical effects of 3,4-methylenedioxymethamphetamine (MDMA) and related amphetamine derivatives on inhibition of uptake of [3H]monoamines into synaptosomes from different regions of rat brain.
    Biochemical pharmacology, 1987, Jul-15, Volume: 36, Issue:14

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamine; Amphetamines; Animals; Biological Transport; Corpus Striatum; Depression, Chemical; DOM 2,5-Dimethoxy-4-Methylamphetamine; Dopamine; Hippocampus; Hypothalamus; Male; N-Methyl-3,4-methylenedioxyamphetamine; Norepinephrine; Rats; Rats, Inbred Strains; Serotonin; Stereoisomerism; Synaptosomes

1987
Behavioral effects of the highly selective serotonin releasing agent 5-methoxy-6-methyl-2-aminoindan.
    European journal of pharmacology, 1994, Jun-02, Volume: 258, Issue:1-2

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamine; Animals; Behavior, Animal; Discrimination Learning; Dose-Response Relationship, Drug; Indans; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Stereoisomerism

1994
Psychostimulant-like effects of p-fluoroamphetamine in the rat.
    European journal of pharmacology, 1995, Dec-12, Volume: 287, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; 3,4-Methylenedioxyamphetamine; Amphetamine; Amphetamines; Animals; Behavior, Animal; Discrimination, Psychological; Dose-Response Relationship, Drug; Male; Microdialysis; Rats; Rats, Sprague-Dawley; Time Factors

1995
Identification of N-methyl-1-(3,4-methylenedioxyphenyl)-2-butanamine (MBDB) in urine from drug users.
    Journal of analytical toxicology, 1996, Volume: 20, Issue:6

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Calibration; Gas Chromatography-Mass Spectrometry; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Reference Standards; Serotonin; Substance-Related Disorders; Sweden

1996
Neuroendocrine pharmacology of three serotonin releasers: 1-(1,3-benzodioxol-5-yl)-2-(methylamino)butane (MBDB), 5-methoxy-6-methyl-2-aminoindan (MMAi) and p-methylthioamphetamine (MTA).
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 279, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Fluoxetine; Indans; Male; Oxytocin; Prolactin; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Vasopressins

1996
Sensitive and selective determination of methylenedioxylated amphetamines by high-performance liquid chromatography with fluorimetric detection.
    Journal of chromatography. A, 1997, Nov-07, Volume: 787, Issue:1-2

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Chromatography, High Pressure Liquid; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Substance Abuse Detection; Tablets

1997
Drug discrimination studies of the interoceptive cues produced by selective serotonin uptake inhibitors and selective serotonin releasing agents.
    Psychopharmacology, 1998, Volume: 138, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Antidepressive Agents, Second-Generation; Citalopram; Conditioning, Operant; Discrimination, Psychological; Fluoxetine; Indans; Male; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists

1998
Serotonin releasers increase prepulse inhibition in serotonin 1B knockout mice.
    Psychopharmacology, 2000, Volume: 149, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Mice; Mice, Knockout; N-Methyl-3,4-methylenedioxyamphetamine; Oxadiazoles; Piperazines; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Reflex, Startle; Serotonin; Serotonin Agents; Serotonin Antagonists

2000
Deaths associated with MBDB misuse.
    International journal of legal medicine, 2000, Volume: 113, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Autopsy; Cause of Death; Dancing; Female; Humans; Male; Substance-Related Disorders; Suicide; United Kingdom

2000
Enantiomer analysis of a new street drug, 3,4-methylenedioxy-N-methyl-butanamine, in rat urine.
    Journal of analytical toxicology, 2002, Volume: 26, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Chromatography, High Pressure Liquid; Illicit Drugs; Male; Rats; Rats, Wistar; Stereoisomerism; Substance Abuse Detection

2002
Ecstasy counteracts catalepsy in rats, an anti-parkinsonian effect?
    Neuroscience letters, 2002, Sep-27, Volume: 330, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Adrenergic Uptake Inhibitors; Animals; Catalepsy; Dopamine Antagonists; Dose-Response Relationship, Drug; Haloperidol; Male; N-Methyl-3,4-methylenedioxyamphetamine; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley

2002
Is the Ecstasy-induced ipsilateral rotation in 6-hydroxydopamine unilaterally lesioned rats dopamine independent?
    Journal of neural transmission (Vienna, Austria : 1996), 2003, Volume: 110, Issue:7

    Topics: 3,4-Methylenedioxyamphetamine; Adrenergic Agents; Animals; Apomorphine; Behavior, Animal; Citalopram; Dopamine; Fenclonine; Functional Laterality; Hallucinogens; Male; Medial Forebrain Bundle; Models, Animal; N-Methyl-3,4-methylenedioxyamphetamine; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Rotation; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists

2003
Determination of MDMA, MDA, MDEA and MBDB in oral fluid using high performance liquid chromatography with native fluorescence detection.
    Forensic science international, 2005, Jun-10, Volume: 150, Issue:2-3

    Topics: 3,4-Methylenedioxyamphetamine; Chromatography, High Pressure Liquid; Forensic Medicine; Hallucinogens; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Saliva; Spectrometry, Fluorescence; Substance Abuse Detection

2005
Ecstasy (MDMA, MDA, MDEA, MBDB) consumption, seizures, related offences, prices, dosage levels and deaths in the UK (1994-2003).
    Journal of psychopharmacology (Oxford, England), 2006, Volume: 20, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamine-Related Disorders; Cause of Death; Crime; Cross-Sectional Studies; Dose-Response Relationship, Drug; Drug and Narcotic Control; Humans; Illicit Drugs; N-Methyl-3,4-methylenedioxyamphetamine; Statistics as Topic; United Kingdom

2006
The disposition into hair of new designer drugs; methylone, MBDB and methcathinone.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2007, Aug-15, Volume: 855, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Gas Chromatography-Mass Spectrometry; Hair; Methamphetamine; Models, Animal; Propiophenones; Rats

2007
Simultaneous analysis of six amphetamines and analogues in hair, blood and urine by LC-ESI-MS/MS. Application to the determination of MDMA after low ecstasy intake.
    Forensic science international, 2007, Aug-06, Volume: 170, Issue:2-3

    Topics: 3,4-Methylenedioxyamphetamine; Adolescent; Amphetamines; Chromatography, Liquid; Female; Forensic Toxicology; Hair; Hallucinogens; Humans; Spectrometry, Mass, Electrospray Ionization; Substance Abuse Detection

2007
Cytotoxic effects of 3,4-methylenedioxy-N-alkylamphetamines, MDMA and its analogues, on isolated rat hepatocytes.
    Archives of toxicology, 2009, Volume: 83, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Adenosine Triphosphate; Animals; Cell Death; DNA Damage; Hallucinogens; Hepatocytes; Male; Methamphetamine; Mitochondria, Liver; N-Methyl-3,4-methylenedioxyamphetamine; Oxidative Phosphorylation; Rats; Rats, Inbred F344; Time Factors

2009
Determination of the metabolites of the new designer drugs bk-MBDB and bk-MDEA in human urine.
    Forensic science international, 2009, Jul-01, Volume: 188, Issue:1-3

    Topics: 3,4-Methylenedioxyamphetamine; Designer Drugs; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Hallucinogens; Humans; Hydrolysis; Methylation

2009
Stereoselective differences in the cytochrome P450-dependent dealkylation and demethylenation of N-methyl-benzodioxolyl-butanamine (MBDB, Eden) enantiomers.
    Biochemical pharmacology, 2009, Jun-01, Volume: 77, Issue:11

    Topics: 3,4-Methylenedioxyamphetamine; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dealkylation; Gas Chromatography-Mass Spectrometry; Humans; Kinetics; Oxidation-Reduction; Oxidoreductases, N-Demethylating; Stereoisomerism; Substrate Specificity

2009
Investigations on the human hepatic cytochrome P450 isozymes involved in the metabolism of 3,4-methylenedioxy-amphetamine (MDA) and benzodioxolyl-butanamine (BDB) enantiomers.
    Toxicology letters, 2009, Oct-08, Volume: 190, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Antibodies, Monoclonal; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Gas Chromatography-Mass Spectrometry; Humans; Illicit Drugs; In Vitro Techniques; Kinetics; Microsomes, Liver; N-Methyl-3,4-methylenedioxyamphetamine; Stereoisomerism

2009
GC-MS studies on side chain regioisomers related to substituted methylenedioxyphenethylamines: MDEA, MDMMA, and MBDB.
    Journal of chromatographic science, 2010, Volume: 48, Issue:9

    Topics: 3,4-Methylenedioxyamphetamine; Gas Chromatography-Mass Spectrometry; Illicit Drugs; Molecular Conformation; Molecular Weight; Stereoisomerism

2010
Liquid chromatography-quadrupole time-of-flight mass spectrometry for screening in vitro drug metabolites in humans: investigation on seven phenethylamine-based designer drugs.
    Journal of pharmaceutical and biomedical analysis, 2015, Oct-10, Volume: 114

    Topics: 3,4-Methylenedioxyamphetamine; Amines; Amphetamines; Benzodioxoles; Benzofurans; Butylamines; Catalysis; Chromatography, Liquid; Cytochrome P-450 Enzyme System; Cytosol; Designer Drugs; Dose-Response Relationship, Drug; Female; Humans; Likelihood Functions; Liver; Male; Mass Spectrometry; Methamphetamine; Microsomes, Liver; Models, Chemical; Phenethylamines; Propylamines; Reproducibility of Results; Substance Abuse Detection; Wastewater; Water Purification

2015