3,4-methylenedioxyamphetamine has been researched along with alpha-methylepinine in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (26.67) | 18.2507 |
| 2000's | 8 (53.33) | 29.6817 |
| 2010's | 3 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brewster, WK; Johnson, MP; Nichols, DE; Steele, TD; Yim, GK | 1 |
| Cho, AK; Chu, TY; Ellis, SW; Hiratsuka, A; Lennard, MS; Lin, LY; Schmitz, DA; Tucker, GT; Woods, HF | 1 |
| Bourquin, D; Bracher, K; Brenneisen, R; Helmlin, HJ; Vonlanthen, D | 1 |
| Atterwill, CK; Davenport-Jones, JE; Fox, RM; Walker, TM | 1 |
| Brenneisen, R; Camí, J; de la Torre, R; Farré, M; Mas, M; Ortuño, J; Roset, PN; Segura, J | 1 |
| Camí, J; de la Torre, R; Farré, M; Hernández-López, C; Joglar, J; Llebaria, A; Mas, M; Ortuño, J; Pizarro, N; Pujadas, M; Roset, PN; Segura, J | 1 |
| de la Torre, R; Farré, M; Joglar, J; Peiró, AM; Pizarro, N; Pujadas, M; Roset, PN | 1 |
| Banks, ML; Czoty, PW; Kisor, DF; Nader, MA; Nichols, DE; Sprague, JE | 1 |
| Maurer, HH; Mueller, M; Peters, FT; Ricaurte, GA | 2 |
| Huestis, MA; Maurer, HH; Mueller, M; Peters, FT; Ricaurte, GA | 1 |
| Felim, A; Largeron, M; Maurer, HH; McCann, UD; Mueller, M; Neudörffer, A; Peters, FT; Ricaurte, GA; Yuan, J | 1 |
| Maldonado Adrian, C; McCann, UD; Mueller, M; Ricaurte, GA; Yuan, J | 1 |
| Almeida, B; Barenys, M; Boix, N; Flick, B; Joglar, J; Klug, S; Llobet, JM | 1 |
| Baumann, MH; Blough, BE; Goldberg, SR; Schindler, CW; Tella, SR; Thorndike, EB | 1 |
3 trial(s) available for 3,4-methylenedioxyamphetamine and alpha-methylepinine
| Article | Year |
|---|---|
Analysis of 3,4-methylenedioxymethamphetamine (MDMA) and its metabolites in plasma and urine by HPLC-DAD and GC-MS.
Topics: 3,4-Methylenedioxyamphetamine; Administration, Oral; Adolescent; Adult; Chromatography, High Pressure Liquid; Deoxyepinephrine; Female; Fluorocarbons; Gas Chromatography-Mass Spectrometry; Hallucinogens; Humans; Hydrolysis; Ion Exchange Resins; Male; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Reference Standards | 1996 |
Non-linear pharmacokinetics of MDMA ('ecstasy') in humans.
Topics: 3,4-Methylenedioxyamphetamine; Adult; Area Under Curve; Blood Pressure; Cross-Over Studies; Deoxyepinephrine; Diastole; Dose-Response Relationship, Drug; Double-Blind Method; Hallucinogens; Humans; Hydrogen-Ion Concentration; Male; Metabolic Clearance Rate; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Pilot Projects; Time Factors | 2000 |
Determination of MDMA and its metabolites in blood and urine by gas chromatography-mass spectrometry and analysis of enantiomers by capillary electrophoresis.
Topics: 3,4-Methylenedioxyamphetamine; Deoxyepinephrine; Electrophoresis, Capillary; Gas Chromatography-Mass Spectrometry; Hallucinogens; Humans; Male; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Reproducibility of Results; Sensitivity and Specificity; Stereoisomerism; Substance Abuse Detection | 2002 |
12 other study(ies) available for 3,4-methylenedioxyamphetamine and alpha-methylepinine
| Article | Year |
|---|---|
Assessment of the role of alpha-methylepinine in the neurotoxicity of MDMA.
Topics: 3,4-Methylenedioxyamphetamine; Animals; Biogenic Amines; Brain Chemistry; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Deoxyepinephrine; Electrochemistry; Injections, Intraventricular; Male; Mice; Microsomes, Liver; N-Methyl-3,4-methylenedioxyamphetamine; Nervous System Diseases; Phenobarbital; Proadifen; Rats; Rats, Inbred Strains; Species Specificity | 1991 |
The demethylenation of methylenedioxymethamphetamine ("ecstasy") by debrisoquine hydroxylase (CYP2D6).
Topics: 3,4-Methylenedioxyamphetamine; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme System; Deoxyepinephrine; Humans; Kinetics; Male; Microsomes, Liver; Middle Aged; Mixed Function Oxygenases; N-Methyl-3,4-methylenedioxyamphetamine; NADP; Saccharomyces cerevisiae; Transfection | 1994 |
The neurotoxic effects of methylenedioxymethamphetamine (MDMA) and its metabolites on rat brain spheroids in culture.
Topics: 3,4-Methylenedioxyamphetamine; Animals; Biomarkers; Brain; Brain Diseases; Cytosol; Deoxyepinephrine; Dose-Response Relationship, Drug; Fetus; Glial Fibrillary Acidic Protein; Glutathione; L-Lactate Dehydrogenase; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Serotonin; Serotonin Agents; Spheroids, Cellular | 1999 |
Stereochemical analysis of 3,4-methylenedioxymethamphetamine and its main metabolites in human samples including the catechol-type metabolite (3,4-dihydroxymethamphetamine).
Topics: 3,4-Methylenedioxyamphetamine; Administration, Oral; Area Under Curve; Catechol O-Methyltransferase; Cytochrome P-450 CYP2D6; Deoxyepinephrine; Half-Life; Humans; Male; Methamphetamine; Methods; Phenotype; Polymorphism, Genetic; Stereoisomerism | 2004 |
Ambient temperature effects on 3,4-methylenedioxymethamphetamine-induced thermodysregulation and pharmacokinetics in male monkeys.
Topics: 3,4-Methylenedioxyamphetamine; Animals; Body Temperature; Deoxyepinephrine; Fever; Hallucinogens; Macaca fascicularis; Male; Serotonin Agents; Temperature | 2007 |
Validated liquid chromatographic-electrospray ionization mass spectrometric assay for simultaneous determination of 3,4-methylenedioxymethamphetamine and its metabolites 3,4-methylenedioxyamphetamine, 3,4-dihydroxymethamphetamine, and 4-hydroxy-3-methoxym
Topics: 3,4-Methylenedioxyamphetamine; Animals; Calibration; Chromatography, Liquid; Deoxyepinephrine; Hallucinogens; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Saimiri; Spectrometry, Mass, Electrospray Ionization | 2007 |
Liquid chromatographic-electrospray ionization mass spectrometric assay for simultaneous determination of 3,4-methylenedioxymethamphetamine and its metabolites 3,4-methylenedioxyamphetamine, 3,4-dihydroxymethamphetamine, and 4-hydroxy-3-methoxymethampheta
Topics: 3,4-Methylenedioxyamphetamine; Animals; Brain; Brain Chemistry; Chromatography, Liquid; Deoxyepinephrine; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization | 2008 |
Simultaneous liquid chromatographic-electrospray ionization mass spectrometric quantification of 3,4-methylenedioxymethamphetamine (MDMA, Ecstasy) and its metabolites 3,4-dihydroxymethamphetamine, 4-hydroxy-3-methoxymethamphetamine and 3,4-methylenedioxya
Topics: 3,4-Methylenedioxyamphetamine; Animals; Chromatography, Liquid; Deoxyepinephrine; Forensic Toxicology; Hallucinogens; Humans; Hydrolysis; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Saimiri; Spectrometry, Mass, Electrospray Ionization | 2009 |
Further studies on the role of metabolites in (+/-)-3,4-methylenedioxymethamphetamine-induced serotonergic neurotoxicity.
Topics: 3,4-Methylenedioxyamphetamine; Animals; Deoxyepinephrine; Disease Models, Animal; Male; N-Methyl-3,4-methylenedioxyamphetamine; Neurotoxicity Syndromes; Rats; Rats, Sprague-Dawley; Serotonin | 2009 |
Inhibition of 3,4-methylenedioxymethamphetamine metabolism leads to marked decrease in 3,4-dihydroxymethamphetamine formation but no change in serotonin neurotoxicity: implications for mechanisms of neurotoxicity.
Topics: 3,4-Methylenedioxyamphetamine; Animals; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Deoxyepinephrine; Dextromethorphan; Excitatory Amino Acid Antagonists; Hydroxyindoleacetic Acid; Male; Neurotoxicity Syndromes; Neurotoxins; Rats; Rats, Sprague-Dawley; Serotonin; Sulfides | 2011 |
Effects of MDMA (ecstasy) and two of its metabolites on rat embryos in vitro.
Topics: 3,4-Methylenedioxyamphetamine; Animals; Deoxyepinephrine; Embryo, Mammalian; Embryonic Development; Female; Hallucinogens; In Vitro Techniques; N-Methyl-3,4-methylenedioxyamphetamine; Pregnancy; Rats; Rats, Sprague-Dawley | 2012 |
Effects of 3,4-methylenedioxymethamphetamine (MDMA) and its main metabolites on cardiovascular function in conscious rats.
Topics: 3,4-Methylenedioxyamphetamine; Adrenergic beta-Antagonists; Animals; Blood Pressure; Cardiovascular System; Consciousness; Deoxyepinephrine; Dopamine; Dose-Response Relationship, Drug; Hallucinogens; Heart Rate; Male; Metabolic Detoxication, Phase I; Methamphetamine; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Sprague-Dawley; Telemetry; Time Factors | 2014 |