3,4-methylenedioxyamphetamine and 3,4-methylenedioxyethamphetamine

3,4-methylenedioxyamphetamine has been researched along with 3,4-methylenedioxyethamphetamine in 150 studies

Research

Studies (150)

TimeframeStudies, this research(%)All Research%
pre-199015 (10.00)18.7374
1990's64 (42.67)18.2507
2000's49 (32.67)29.6817
2010's20 (13.33)24.3611
2020's2 (1.33)2.80

Authors

AuthorsStudies
Clare, BW1
Chei, DM; Foltz, RL; Lim, HK; Zeng, S1
Ensslin, M; Gouzoulis, E; Hermle, L; Kovar, A; Steiger, A1
Axt, KJ; Molliver, ME; Mullen, CA1
Battaglia, G; de Souza, EB; Kuhar, MJ; Sharkey, J1
Boja, JW; Schechter, MD2
Blanke, RV; Fitzgerald, RL; Glennon, RA; Narasimhachari, N; Rosecrans, JA; Yousif, MY1
Blanke, RV; Fitzgerald, RL; Poklis, A1
Gibb, JW; Hanson, GR; Johnson, M2
Barrett, JE; Hoffmann, SM; Nader, MA1
Glennon, RA; Misenheimer, BR1
Braff, DL; Geyer, MA; Mansbach, RS1
Bost, RO; Dowling, GP; McDonough, ET1
Gibb, JW; Hanson, GR; Johnson, M; Stone, DM1
Schmidt, CJ1
DeLanney, LE; Finnegan, KF; Irwin, I; Langston, JW; Nichols, DE; Ricaurte, GA1
Glennon, RA; Patrick, G; Yousif, M1
Geyer, MA; Gold, LH; Koob, GF1
Laverty, R; Logan, BJ; Sanderson, WD; Yee, YB1
Peroutka, SJ; Pierce, PA1
Schechter, MD1
Hardern, R; Tehan, B1
Harvey, JA; McMaster, SE; Romano, AG1
Kelly, PA; McBean, DE; Olverman, HJ; Ritchie, IM; Sharkey, J1
George, WJ; Michel, RE; Rege, AB1
Nakahara, Y; Shimamine, M; Takahashi, K1
Molliver, ME; Series, HG1
Borchardt, D; Gouzoulis, E; Hermle, L1
De Man, RA; Ijzermans, JN; Metselaar, HJ; Tilanus, HW1
Bodenham, A; Hardern, R; Tehan, B1
Berger, M; Borchardt, D; Fünfgeld, M; Gouzoulis, E; Hermle, L; Kovar, KA; Oepen, G; Spitzer, M1
Borchardt, D; Gouzoulis, E; Hermle, L; Kovar, KA; Spitzer, M1
Gouzoulis, E; Hermle, L; Kovar, KA; Rupp, A; von Bardeleben, U1
Iwersen, S; Schmoldt, A1
Korten, JJ; Roebroek, RM1
Clark, JC; Forrest, AR; Milroy, CM1
Cox, DE; Williams, KR1
Brown, ER; Jarvie, DR; Simpson, D1
Fineschi, V; Masti, A1
Tucker, G1
Merrill, J1
Saunders, N1
King, LA; Winstock, AR1
Dalgarno, P; Shewan, D1
Ryan, JM; Stell, JM1
Kauert, G; Röhrich, J1
Andries, S; Bossaert, L; Demey, HE; Heytens, L; Jorens, PG; Ricaurte, GA; Schepens, PJ1
Balanzó, X; Camí, J; de la Torre, R; Rafel, J1
Ensslin, HK; Gouzoulis, E; Hermle, L; Kovar, KA; Maurer, HH1
Keogh, G; Trenerry, VC; Vandepeer, J1
Ensslin, HK; Kovar, KA; Maurer, HH1
Burroughs, A; Dhillon, A; Fidler, H; Gertner, D1
Gouzoulis-Mayfrank, E; Hermle, L; Kovar, KA; Sass, H1
Barni Comparini, I; Centini, F; Masti, A1
Assion, HJ; Heinemann, F1
Kikura, R; Mieczkowski, T; Nakahara, Y; Tagliaro, F1
Barrio Anta, G; de la Fuente de Hoz, L; Rodríguez Arenas, MA; Sánchez Payá, J; Vicente Orta, J1
Michalodimitrakis, MN; Patsalis, AN; Tsatsakis, AM1
Hall, AP1
Sadeghipour, F; Veuthey, JL1
Bogusz, MJ1
Bollani, T; Favretto, D; Garofano, L; Guidugli, F; Patri, P; Santoro, M; Traldi, P1
Arimany, J; Borondo, JC; Medallo, J; Pujol, A; Valverde, JL; Vingut, A1
Dirnhofer, R; Keller, T; Miki, A; Regenscheit, P; Schneider, A; Tsuchihashi, H1
Kovar, KA1
Brunnenberg, M; Gouzoulis-Mayfrank, E; Kovar, KA; Lindenblatt, H1
Baker, GB; Bourin, M; Hegadoren, KM1
Gouzoulis-Mayfrank, E; Habermeyer, E; Hermle, L; Kovar, KA; Kunert, HJ; Lindenblatt, H; Sass, H; Spitzer, M; Thelen, B1
Arning, C; Büll, U; Gouzoulis-Mayfrank, E; Hermle, L; Kovar, KA; Sabri, O; Sass, H; Schreckenberger, M; Spitzer, M; Thelen, B1
Colado, MI; Esteban, B; Granados, R; Green, AR; O'Shea, E1
Felgenhauer, N; Zilker, T1
Cody, JT; Hensley, D1
Centini, F; Fineschi, V; Mazzeo, E; Turillazzi, E1
Arning, C; Buell, U; Gouzoulis-Mayfrank, E; Kaiser, HJ; Sabri, O; Sass, H; Schreckenberger, M; Wagenknecht, G; Zeggel, T; Zimny, M1
Aguirre, N; Barrionuevo, M; Del Río, JD; Lasheras, B1
Allen, DL; Oliver, JS1
Krogh, M; Rasmussen, KE; Ugland, HG1
Dawson, M; Kannangara, GS; Lee, GS; Taylor, RC; Wilson, MA1
Clauwaert, KM; De Leenheer, AP; De Letter, EA; Lambert, WE; Van Bocxlaer, JF; Van Calenbergh, S1
Gresham, GL; Groenewold, GS; Olson, JE1
Brunnenberg, M; Kovar, KA1
Gudelsky, GA; Vorhees, CV; Wallace, TL1
Mirken, B1
Boland, G; Kelly, JP; O'Boyle, KM; O'Loinsigh, ED1
Campíns-Falcó, P; Herráez-Hernández, R; Verdú-Andrés, J1
Buechler, J; Franke, B; Grön, G; Hermle, L; Kovar, KA; Schwab, M; Spitzer, M; Walter, H; Wunderlich, AP1
Clauwaert, KM; De Leenheer, AP; Van Bocxlaer, JF1
Brehm, G; Sägmüller, B; Schneider, S; Schwarze, B1
Gouzoulis-Mayfrank, E; Heekeren, K; Kovar, KA; Maier, S; Sass, H; Spitzer, M; Thelen, B1
Barnett, DA; Ells, B; Guevremont, R; McCooeye, MA; Mester, Z; Purves, RW1
Kovar, KA; Mayerhofer, A; Meyer, A; Schmidt, WJ1
Broening, HW; Fukumura, M; McCrea, AE; Moran, MS; Morford, LL; Rock, SL; Vorhees, CV; Wallace, TL; Williams, MT; Wood, SL1
Cole, JC; Sumnall, HR1
Cooper, DP; De Boeck, G; De Bruijn, EA; Maes, RA; Morris, M; Samyn, N; Wood, M1
Kovar, KA; Lebsanft, HB; Mayerhofer, A; Schmidt, WJ1
Buechler, J; Fischer, B; Grön, G; Hermle, L; Kovar, KA; Marx, C; Mikus, G; Schwab, M; Spitzer, M1
Cleary, L; Docherty, JR1
Parrott, AC1
Katagi, M; Miki, A; Shima, N; Tsuchihashi, H1
Freudenmann, RW; Spitzer, M1
da Costa, JL; da Matta Chasin, AA1
Jacobs, A; Jemionek, J; Lesser, D; Paul, BD; Searles, DA1
Belzung, C; Bodard, S; Chalon, S; Galineau, L; Guilloteau, D; Kodas, E1
Bronselaer, K; De Feyter, K; De Munnynck, K; Sabbe, M; Smets, G; Van de Voorde, W1
de Boeck, G; Kraemer, T; Lamers, CT; Maurer, HH; Peters, FT; Riedel, WJ; Samyn, N1
Grubwieser, P; Libiseller, K; Pavlic, M; Rabl, W1
Bouche, MP; Casteele, SR; Van Bocxlaer, JF1
Carney, B; Gillespie, J; Mc Fadden, K; O'Driscoll, D1
Bexis, S; Docherty, JR1
Corkery, J; Deluca, P; Ghodse, AH; Oyefeso, A; Schifano, F1
Johansen, SS; Olsen, KH; Rasmussen, LB1
Blessing, WW; Ootsuka, Y; Zilm, A1
Abraham, TT; Huestis, MA; Pirnay, SO1
Martins, LF; Ramaekers, JG; Samyn, N; Wennig, R; Yegles, M1
Cody, JT; Phelix, CF; Valtier, S1
Chèze, M; Deveaux, M; Lhermitte, M; Martin, C; Pépin, G1
Maurer, HH; Mueller, M; Peters, FT; Ricaurte, GA1
Huestis, MA; Kolbrich, EA; Lowe, RH1
Irvine, RJ; Jaehne, EJ; Salem, A1
de Ruiter, A; Hritz, J; Oostenbrink, C1
Cheong, JC; In, MK; Jin, C; Kim, JY; Ko, BJ; Lee, SK; Yoo, HH1
Maurer, HH; Meyer, MR; Peters, FT1
Kamata, HT; Kamata, T; Katagi, M; Miki, A; Mori, Y; Shima, N; Tsuchihashi, H; Zaitsu, K1
Maurer, HH; Meyer, MR1
Abraham, TT; Barnes, AJ; Goodwin, RS; Gorelick, DA; Huestis, MA; Kolbrich Spargo, EA; Lowe, RH; Milman, G; Pirnay, SO1
Hritz, J; Oostenbrink, C; Santos, R1
Awad, T; Belal, T; Clark, CR; DeRuiter, J; Maher, HM1
Buchanan, T; Gates, J; Heffernan, T; Ling, J; Owen, L; Parrott, AC; Rodgers, J; Scholey, AB; Stough, C; Swan, P1
Blacik, LJ; Kazarian, CM; Ntamack, AG; Romberg, RW; Snyder, JJ; Welsh, ER1
Maldonado Adrian, C; McCann, UD; Mueller, M; Ricaurte, GA; Yuan, J1
Chen, BH; Chen, PH; Lee, HH; Lee, JF; Lin, SY1
Baylor, MR; Bynum, ND; Lewallen, CM; Mitchell, JM; Ropero-Miller, JD; Stout, PR1
Hara, K; Hasegawa, C; Kumazawa, T; Lee, XP; Sato, K; Seno, H; Suzuki, O; Uchigasaki, S1
Galceran, MT; Huerta-Fontela, M; Pineda, O; Ventura, F1
Maurer, HH; Meyer, MR; Schwaninger, AE; Zapp, J1
Gudelsky, GA; Johnson, BN; Weber, GF; Yamamoto, BK1
Borrell, JI; Camarasa, J; Cristóbal-Lecina, E; Escubedo, E; García-Ratés, S; Llabrés, S; Luque, FJ; Pubill, D; Riera, A1
Baritussio, A; Bigler, L; Calistri, A; Fabris, F; Ha, HR; Mirazimi, A; Munegato, D; Palù, G; Parolin, C; Salata, C1
Covaci, A; Kinyua, J; Mardal, M; Meyer, MR; Miserez, B; Ramin, P; Van Nuijs, AL1
Datye, A; Jiang, Y; Kauffman, AC; Nakazawa, KH; Piotrowski-Daspit, AS; Saltzman, WM1
Blanes, L; Bordin, DM; de Campos, EG; De Martinis, BS; Doble, P; Ishikawa, AA1
Murnane, KS1
Fatehi, M; Haw, CS; Heran, MKS; Nugent, JP1
Browne, G; McGettigan, S; Ronan, GP; Ronan, N1
Burgueño, MJ; Castro, MÁ; Mateos-Campos, R; Sánchez, S1
Angenoorth, TJF; Brandt, SD; Holy, M; Maier, J; Niello, M; Sitte, HH; Stankovic, S1
Mafi, M; Mortaheb, HR; Nozaeim, AA; Tavasoli, A1

Reviews

10 review(s) available for 3,4-methylenedioxyamphetamine and 3,4-methylenedioxyethamphetamine

ArticleYear
Hyperthermia associated with 3,4-methylenedioxyethamphetamine ('Eve').
    Anaesthesia, 1993, Volume: 48, Issue:6

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Designer Drugs; Fever; Humans; Male; Poisoning; Substance-Related Disorders

1993
[Significance of historical and current hallucinogenic research in psychiatry].
    Der Nervenarzt, 1993, Volume: 64, Issue:9

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Arousal; Designer Drugs; Dose-Response Relationship, Drug; Forecasting; Hallucinations; Hallucinogens; Humans; Mescaline; Middle Aged; Psychiatric Status Rating Scales; Psychoses, Substance-Induced

1993
[Entactogenic drugs "ecstasy" (MDMA), "eve" (MDE) and other ring-substituted methamphetamine derivatives. A new class of substances among illegal designer drugs?].
    Der Nervenarzt, 1996, Volume: 67, Issue:5

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Designer Drugs; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Risk Factors; Substance Withdrawal Syndrome; Substance-Related Disorders

1996
MDEA related death in Crete: a case report and literature review.
    Veterinary and human toxicology, 1997, Volume: 39, Issue:4

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Designer Drugs; Fatal Outcome; Greece; Humans; Male

1997
Chemistry and pharmacology of hallucinogens, entactogens and stimulants.
    Pharmacopsychiatry, 1998, Volume: 31 Suppl 2

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Brain; Central Nervous System Stimulants; Hallucinogens; Humans; Mescaline; N-Methyl-3,4-methylenedioxyamphetamine; Structure-Activity Relationship

1998
3,4-Methylenedioxy analogues of amphetamine: defining the risks to humans.
    Neuroscience and biobehavioral reviews, 1999, Volume: 23, Issue:4

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Designer Drugs; Dopamine Uptake Inhibitors; Hallucinogens; Humans

1999
[Poisoning with amphetamines and designer drugs].
    Der Internist, 1999, Volume: 40, Issue:6

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Designer Drugs; Drug Overdose; Humans; Illicit Drugs; Internal Medicine; N-Methyl-3,4-methylenedioxyamphetamine; Serotonin Syndrome; Substance-Related Disorders

1999
Altered states: the clinical effects of Ecstasy.
    Pharmacology & therapeutics, 2003, Volume: 98, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Brain; Clinical Trials as Topic; Cognition Disorders; Hallucinogens; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Substance-Related Disorders

2003
The Neuropsychopharmacology and Toxicology of 3,4-methylenedioxy-N-ethyl-amphetamine (MDEA).
    CNS drug reviews, 2004,Summer, Volume: 10, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Drug Administration Schedule; Drug Interactions; Europe; Hallucinogens; Humans; Illicit Drugs; Mental Disorders; N-Methyl-3,4-methylenedioxyamphetamine; Nervous System Diseases; Neurotoxins; North America

2004
Serotonin 2A receptors are a stress response system: implications for post-traumatic stress disorder.
    Behavioural pharmacology, 2019, Volume: 30, Issue:2 and 3-Sp

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Brain; Cues; Gene Expression; Gene Expression Regulation; Humans; Learning; Receptor, Serotonin, 5-HT2A; Serotonin; Stress Disorders, Post-Traumatic; Stress, Physiological

2019

Trials

10 trial(s) available for 3,4-methylenedioxyamphetamine and 3,4-methylenedioxyethamphetamine

ArticleYear
Sleep EEG effects of 3,4-methylenedioxyethamphetamine (MDE; "eve") in healthy volunteers.
    Biological psychiatry, 1992, Dec-15, Volume: 32, Issue:12

    Topics: 3,4-Methylenedioxyamphetamine; Administration, Oral; Adult; Double-Blind Method; Electroencephalography; Female; Humans; Male; Polysomnography; Sleep Stages; Sleep, REM

1992
Psychological effects of MDE in normal subjects. Are entactogens a new class of psychoactive agents?
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1993, Volume: 8, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Double-Blind Method; Female; Humans; Male; Mental Disorders; Middle Aged; Psychiatric Status Rating Scales; Psychological Tests; Reference Values

1993
Neuroendocrine and cardiovascular effects of MDE in healthy volunteers.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1993, Volume: 8, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Blood Pressure; Designer Drugs; Double-Blind Method; Heart Rate; Hemodynamics; Hormones; Humans; Male; Middle Aged; Polysomnography

1993
Quantitation of N-ethyl-3,4-methylenedioxyamphetamine and its major metabolites in human plasma by high-performance liquid chromatography and fluorescence detection.
    Journal of chromatography. B, Biomedical sciences and applications, 1998, Nov-20, Volume: 719, Issue:1-2

    Topics: 3,4-Methylenedioxyamphetamine; Chromatography, High Pressure Liquid; Designer Drugs; Humans; Reference Values; Spectrometry, Fluorescence

1998
Psychopathological, neuroendocrine and autonomic effects of 3,4-methylenedioxyethylamphetamine (MDE), psilocybin and d-methamphetamine in healthy volunteers. Results of an experimental double-blind placebo-controlled study.
    Psychopharmacology, 1999, Volume: 142, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Acute-Phase Reaction; Adult; Aged; Autonomic Agents; Central Nervous System Stimulants; Double-Blind Method; Female; Hallucinogens; Humans; Male; Methamphetamine; Middle Aged; Neurosecretory Systems; Psilocybin; Psychopathology

1999
Neurometabolic effects of psilocybin, 3,4-methylenedioxyethylamphetamine (MDE) and d-methamphetamine in healthy volunteers. A double-blind, placebo-controlled PET study with [18F]FDG.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1999, Volume: 20, Issue:6

    Topics: 3,4-Methylenedioxyamphetamine; Adrenergic Agents; Adult; Cerebellum; Cognition; Double-Blind Method; Female; Glucose; Hallucinogens; Humans; Magnetic Resonance Imaging; Male; Methamphetamine; Middle Aged; Nootropic Agents; Psilocybin; Psychopathology; Radionuclide Imaging

1999
"Ecstasy"-induced changes of cerebral glucose metabolism and their correlation to acute psychopathology. An 18-FDG PET study.
    European journal of nuclear medicine, 1999, Volume: 26, Issue:12

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Cerebral Cortex; Double-Blind Method; Female; Fluorodeoxyglucose F18; Glucose; Humans; Male; Mental Disorders; Middle Aged; Psychological Tests; Radionuclide Imaging; Radiopharmaceuticals

1999
Enantio-selective cognitive and brain activation effects of N-ethyl-3,4-methylenedioxyamphetamine in humans.
    Neuropharmacology, 2001, Volume: 41, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Analysis of Variance; Brain; Cognition; Double-Blind Method; Humans; Magnetic Resonance Imaging; Male; Neuropsychological Tests; Psychometrics; Statistics, Nonparametric; Stereoisomerism

2001
Effects of the hallucinogen psilocybin on covert orienting of visual attention in humans.
    Neuropsychobiology, 2002, Volume: 45, Issue:4

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Attention; Central Nervous System Stimulants; Double-Blind Method; Female; Hallucinogens; Humans; Male; Methamphetamine; Middle Aged; Psilocybin; Reaction Time; Space Perception; Visual Perception

2002
Enantioselective quantitation of the ecstasy compound (R)- and (S)-N-ethyl-3,4-methylenedioxyamphetamine and its major metabolites in human plasma and urine.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2003, Aug-15, Volume: 793, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Chromatography, High Pressure Liquid; Cross-Over Studies; Double-Blind Method; Humans; Male; Middle Aged; Pilot Projects; Reproducibility of Results; Spectrometry, Fluorescence; Stereoisomerism

2003

Other Studies

130 other study(ies) available for 3,4-methylenedioxyamphetamine and 3,4-methylenedioxyethamphetamine

ArticleYear
The frontier orbital phase angles: novel QSAR descriptors for benzene derivatives, applied to phenylalkylamine hallucinogens.
    Journal of medicinal chemistry, 1998, Sep-24, Volume: 41, Issue:20

    Topics: Hallucinogens; Humans; Models, Molecular; Molecular Conformation; Phenethylamines; Quantum Theory

1998
Comparative investigation of disposition of 3,4-(methylenedioxy)methamphetamine (MDMA) in the rat and the mouse by a capillary gas chromatography-mass spectrometry assay based on perfluorotributylamine-enhanced ammonia positive ion chemical ionization.
    Journal of pharmaceutical and biomedical analysis, 1992, Volume: 10, Issue:9

    Topics: 3,4-Methylenedioxyamphetamine; Ammonia; Animals; Dopamine; Fluorocarbons; Gas Chromatography-Mass Spectrometry; Male; Methamphetamine; Mice; Mice, Inbred Strains; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Sprague-Dawley; Species Specificity

1992
Cytopathologic features indicative of 5-hydroxytryptamine axon degeneration are observed in rat brain after administration of d- and l-methylenedioxyamphetamine.
    Annals of the New York Academy of Sciences, 1992, May-11, Volume: 648

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Axons; Brain; Designer Drugs; Isomerism; Neurotoxins; Prosencephalon; Rats; Serotonin

1992
Neuroanatomic specificity and time course of alterations in rat brain serotonergic pathways induced by MDMA (3,4-methylenedioxymethamphetamine): assessment using quantitative autoradiography.
    Synapse (New York, N.Y.), 1991, Volume: 8, Issue:4

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Autoradiography; Brain; Dopamine; Male; Mazindol; N-Methyl-3,4-methylenedioxyamphetamine; Neural Pathways; Norepinephrine; Paroxetine; Piperidines; Rats; Rats, Inbred Strains; Reference Values; Serotonin; Time Factors

1991
Possible serotonergic and dopaminergic mediation of the N-ethyl-3,4-methylenedioxyamphetamine discriminative stimulus.
    European journal of pharmacology, 1991, Sep-24, Volume: 202, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Designer Drugs; Discrimination Learning; Fenclonine; Male; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Serotonin; Serotonin; Serotonin Antagonists

1991
Identification of metabolites of 3,4-methylenedioxymethamphetamine in rats.
    Drug and alcohol dependence, 1990, Volume: 26, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Chromatography, High Pressure Liquid; Designer Drugs; Gas Chromatography-Mass Spectrometry; Inactivation, Metabolic; Injections, Subcutaneous; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains

1990
Stereoselective pharmacokinetics of 3,4-methylenedioxymethamphetamine in the rat.
    Chirality, 1990, Volume: 2, Issue:4

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Hematocrit; Metabolic Clearance Rate; Rats; Rats, Inbred Strains; Stereoisomerism; Structure-Activity Relationship

1990
Effects of N-ethyl-3,4-methylenedioxyamphetamine (MDE) on central serotonergic and dopaminergic systems of the rat.
    Biochemical pharmacology, 1987, Dec-01, Volume: 36, Issue:23

    Topics: 3,4-Dihydroxyphenylacetic Acid; 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Brain; Corpus Striatum; Dopamine; Frontal Lobe; Hippocampus; Homovanillic Acid; Hydroxyindoleacetic Acid; Hypothalamus; Male; Rats; Rats, Inbred Strains; Serotonin; Tryptophan Hydroxylase; Tyrosine 3-Monooxygenase

1987
Characterization of acute N-ethyl-3,4-methylenedioxyamphetamine (MDE) action on the central serotonergic system.
    Biochemical pharmacology, 1989, Dec-01, Volume: 38, Issue:23

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Analysis of Variance; Animals; Drug Interactions; Fluoxetine; Frontal Lobe; Hippocampus; Hydroxyindoleacetic Acid; Male; Monoamine Oxidase; Pargyline; Rats; Rats, Inbred Strains; Serotonin; Tryptophan Hydroxylase

1989
Behavioral effects of (+-) 3,4-methylenedioxyamphetamine (MDA) and (+-) 3,4-methylenedioxymethamphetamine (MDMA) in the pigeon: interactions with noradrenergic and serotonergic systems.
    Psychopharmacology, 1989, Volume: 98, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Behavior, Animal; Columbidae; Conditioning, Operant; Dose-Response Relationship, Drug; Female; Ketanserin; Male; Metergoline; N-Methyl-3,4-methylenedioxyamphetamine; Norepinephrine; Prazosin; Reinforcement Schedule; Serotonin; Sympathetic Nervous System

1989
Stimulus effects of N-monoethyl-1-(3,4-methylenedioxyphenyl)-2-aminopropane (MDE) and N-hydroxy-1-(3,4-methylenedioxyphenyl)-2-aminopropane (N-OH MDA) in rats trained to discriminate MDMA from saline.
    Pharmacology, biochemistry, and behavior, 1989, Volume: 33, Issue:4

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamine; Amphetamines; Animals; Discrimination, Psychological; Dose-Response Relationship, Drug; Generalization, Stimulus; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains

1989
Prepulse inhibition of the acoustic startle response is disrupted by N-ethyl-3,4-methylenedioxyamphetamine (MDEA) in the rat.
    European journal of pharmacology, 1989, Aug-11, Volume: 167, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Acoustic Stimulation; Amphetamines; Analysis of Variance; Animals; Chemical Phenomena; Chemistry; Isomerism; Male; Rats; Rats, Inbred Strains; Reflex, Startle

1989
'Eve' and 'Ecstasy'. A report of five deaths associated with the use of MDEA and MDMA.
    JAMA, 1987, Mar-27, Volume: 257, Issue:12

    Topics: 3,4-Methylenedioxyamphetamine; Accidents; Adolescent; Adult; Amphetamines; Arrhythmias, Cardiac; Asthma; Chromatography, Gas; Female; Gas Chromatography-Mass Spectrometry; Heart Diseases; Humans; Male; N-Methyl-3,4-methylenedioxyamphetamine

1987
A comparison of the neurotoxic potential of methylenedioxyamphetamine (MDA) and its N-methylated and N-ethylated derivatives.
    European journal of pharmacology, 1987, Feb-10, Volume: 134, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Brain; Corpus Striatum; Dopamine; Homovanillic Acid; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Tryptophan Hydroxylase; Tyrosine 3-Monooxygenase

1987
Acute administration of methylenedioxymethamphetamine: comparison with the neurochemical effects of its N-desmethyl and N-ethyl analogs.
    European journal of pharmacology, 1987, Apr-07, Volume: 136, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Brain Chemistry; Cerebral Cortex; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Serotonin; Stereoisomerism; Synaptosomes

1987
3,4-Methylenedioxyethylamphetamine (MDE), a novel analogue of MDMA, produces long-lasting depletion of serotonin in the rat brain.
    European journal of pharmacology, 1987, Jun-04, Volume: 137, Issue:2-3

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Brain; Dopamine; Dose-Response Relationship, Drug; Male; N-Methyl-3,4-methylenedioxyamphetamine; Norepinephrine; Rats; Rats, Inbred Strains; Serotonin

1987
Behavioral effects of N-ethyl-3,4-methylenedioxyamphetamine (MDE; "EVE").
    Pharmacology, biochemistry, and behavior, 1987, Volume: 28, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Discrimination, Psychological; Dose-Response Relationship, Drug; Legislation, Drug; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Time Factors; United States

1987
Stimulus properties of 1-(3,4-methylenedioxyphenyl)-2-aminopropane (MDA) analogs.
    Pharmacology, biochemistry, and behavior, 1988, Volume: 29, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Dextroamphetamine; Discrimination Learning; DOM 2,5-Dimethoxy-4-Methylamphetamine; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Stereoisomerism

1988
Stimulant and hallucinogenic behavioral profiles of 3,4-methylenedioxymethamphetamine and N-ethyl-3,4-methylenedioxyamphetamine in rats.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 247, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Behavior, Animal; Hallucinogens; Male; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Time Factors

1988
Differences between rats and mice in MDMA (methylenedioxymethylamphetamine) neurotoxicity.
    European journal of pharmacology, 1988, Aug-02, Volume: 152, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Biogenic Monoamines; Dopamine; Male; Methoxyhydroxyphenylglycol; Mice; N-Methyl-3,4-methylenedioxyamphetamine; Nervous System Diseases; Norepinephrine; Rats; Species Specificity

1988
Ring-substituted amphetamine interactions with neurotransmitter receptor binding sites in human cortex.
    Neuroscience letters, 1988, Dec-19, Volume: 95, Issue:1-3

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Cerebral Cortex; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Receptors, Neurotransmitter

1988
Serotonergic-dopaminergic mediation of 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy").
    Pharmacology, biochemistry, and behavior, 1988, Volume: 31, Issue:4

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Discrimination, Psychological; Dopamine Agents; Dopamine Antagonists; Dose-Response Relationship, Drug; Generalization, Stimulus; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists; Time Factors

1988
Ecstasy toxicity.
    Journal of accident & emergency medicine, 1995, Volume: 12, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Charcoal; Designer Drugs; Drug Overdose; Humans; Tablets

1995
Methylenedioxyamphetamine: neurotoxic effects on serotonergic projections to brainstem nuclei in the rat.
    Brain research, 1993, Aug-13, Volume: 619, Issue:1-2

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Axonal Transport; Axons; Brain Stem; Designer Drugs; Fluoxetine; Immunohistochemistry; Male; Nerve Fibers; Neurotoxins; Prosencephalon; Rats; Rats, Sprague-Dawley; Serotonin

1993
Enhanced cerebrovascular responsiveness to hypercapnia following depletion of central serotonergic terminals.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1995, Volume: 15, Issue:4

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Antipyrine; Autoradiography; Brain; Cerebrovascular Circulation; Deoxyglucose; Hypercapnia; Male; Nerve Endings; Paroxetine; Rats; Rats, Sprague-Dawley; Serotonin; Tritium

1995
High-pressure liquid chromatography/electrochemical detection method for monitoring MDA and MDMA in whole blood and other biological tissues.
    Journal of neuroscience methods, 1993, Volume: 50, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Chromatography, High Pressure Liquid; Designer Drugs; Electrochemistry; Evaluation Studies as Topic; N-Methyl-3,4-methylenedioxyamphetamine

1993
[Studies on the identification of psychotropic substances. IX. Preparation and various analytical data of reference standard of new psychotropic substances, N-ethyl methylenedioxyamphetamine, N-hydroxy methylenedioxyamphetamine, mecloqualone, 4-methylamin
    Eisei Shikenjo hokoku. Bulletin of National Institute of Hygienic Sciences, 1993, Issue:111

    Topics: 3,4-Methylenedioxyamphetamine; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Gas Chromatography-Mass Spectrometry; Morpholines; Oxazoles; Phenmetrazine; Psychotropic Drugs; Quinazolines; Spectrophotometry

1993
Immunocytochemical evidence for serotonergic neurotoxicity of N-ethyl-methylenedioxyamphetamine (MDE).
    Experimental neurology, 1994, Volume: 128, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Brain; Cell Survival; Immunohistochemistry; Male; Neurons; p-Chloroamphetamine; Rats; Rats, Sprague-Dawley; Serotonin; Time Factors

1994
A case of toxic psychosis induced by 'eve' (3,4-methylene-dioxyethylam-phetamine)
    Archives of general psychiatry, 1993, Volume: 50, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Administration, Oral; Adult; Humans; Male; N-Methyl-3,4-methylenedioxyamphetamine; Psychoses, Substance-Induced; Substance-Related Disorders

1993
"Ecstasy" and liver transplantation.
    Annales de medecine interne, 1993, Volume: 144, Issue:8

    Topics: 3,4-Methylenedioxyamphetamine; Adolescent; Adult; Female; Hallucinogens; Humans; Liver Failure, Acute; Liver Transplantation; Male

1993
Two very different fatal cases associated with the use of methylenedioxyethylamphetamine (MDEA): Eve as deadly as Adam.
    Journal of toxicology. Clinical toxicology, 1996, Volume: 34, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Designer Drugs; Fatal Outcome; Fever; Humans; Male; Psychoses, Substance-Induced; Suicide

1996
[Epileptic insults, cerebral infarction and rhabdomyolysis as complications of amphetamine use].
    Nederlands tijdschrift voor geneeskunde, 1996, Jan-27, Volume: 140, Issue:4

    Topics: 3,4-Methylenedioxyamphetamine; Adolescent; Cerebral Infarction; Designer Drugs; Epilepsy, Generalized; Humans; Male; Rhabdomyolysis; Substance-Related Disorders

1996
Pathology of deaths associated with "ecstasy" and "eve" misuse.
    Journal of clinical pathology, 1996, Volume: 49, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Brain; Humans; Liver; Male; Myocardium; N-Methyl-3,4-methylenedioxyamphetamine; Substance-Related Disorders

1996
"ADAM' or "EVE'?--a toxicological conundrum.
    Forensic science international, 1996, Jan-12, Volume: 77, Issue:1-2

    Topics: 3,4-Methylenedioxyamphetamine; Adolescent; Adult; Amphetamine; Female; Homicide; Humans; Male; N-Methyl-3,4-methylenedioxyamphetamine

1996
Use of drugs at 'raves'.
    Scottish medical journal, 1995, Volume: 40, Issue:6

    Topics: 3,4-Methylenedioxyamphetamine; Adolescent; Adult; Catha; Central Nervous System Stimulants; Dancing; Designer Drugs; Female; Hallucinogens; Humans; Lysergic Acid Diethylamide; Male; N-Methyl-3,4-methylenedioxyamphetamine; Plant Extracts; Scotland; Substance-Related Disorders; Surveys and Questionnaires

1995
Fatal poisoning by MDMA (ecstasy) and MDEA: a case report.
    International journal of legal medicine, 1996, Volume: 108, Issue:5

    Topics: 3,4-Methylenedioxyamphetamine; Capillaries; Designer Drugs; Drug Overdose; Fluorescent Antibody Technique; Gas Chromatography-Mass Spectrometry; Hallucinogens; Humans; Kidney Tubules; Lung; Myoglobinuria; N-Methyl-3,4-methylenedioxyamphetamine; Poisoning; Pulmonary Embolism

1996
Adam and Eve make love. Analysis of the enantiomers of 3,4-methylenedioxy-N-ethylamphetamine (MDE, "Eve") and its metabolite 3,4-methylenedioxyamphetamine (MDA) in rat brain.
    Human & experimental toxicology, 1996, Volume: 15, Issue:5

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Brain; Designer Drugs; Hallucinogens; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Stereoisomerism

1996
Ecstasy and neurodegeneration. Advice is that "less is more".
    BMJ (Clinical research ed.), 1996, Aug-17, Volume: 313, Issue:7054

    Topics: 3,4-Methylenedioxyamphetamine; Chronic Disease; Designer Drugs; Humans; Nervous System Diseases; Risk Factors

1996
Ecstasy and neurodegeneration. No evidence of neurotoxicity exists.
    BMJ (Clinical research ed.), 1996, Aug-17, Volume: 313, Issue:7054

    Topics: 3,4-Methylenedioxyamphetamine; Brain Diseases; Chronic Disease; Designer Drugs; Humans; Nervous System Diseases

1996
Ecstasy and neurodegeneration. Tablets often contain substances in addition to, or instead of, ecstasy...
    BMJ (Clinical research ed.), 1996, Aug-17, Volume: 313, Issue:7054

    Topics: 3,4-Methylenedioxyamphetamine; Designer Drugs; Drug Contamination; Humans; Nervous System Diseases; Tablets

1996
Ecstasy and neurodegeneration. ...such as ketamine.
    BMJ (Clinical research ed.), 1996, Aug-17, Volume: 313, Issue:7054

    Topics: 3,4-Methylenedioxyamphetamine; Designer Drugs; Drug Contamination; Ephedrine; Hallucinogens; Humans; Ketamine; Substance-Related Disorders; Tablets

1996
Ecstasy and neurodegeneration. gamma-Hydroxybutyrate is a new recreational drug that may lead to loss of consciousness.
    BMJ (Clinical research ed.), 1996, Aug-17, Volume: 313, Issue:7054

    Topics: 3,4-Methylenedioxyamphetamine; Designer Drugs; Diagnosis, Differential; Humans; Seizures; Sodium Oxybate; Substance-Related Disorders; Unconsciousness

1996
Concentrations of delta 9-tetrahydrocannabinol, cocaine and 6-monoacetylmorphine in hair of drug abusers.
    International journal of legal medicine, 1996, Volume: 108, Issue:6

    Topics: 3,4-Methylenedioxyamphetamine; Accidents, Traffic; Amphetamine; Cocaine; Crime; Designer Drugs; Dronabinol; Expert Testimony; Gas Chromatography-Mass Spectrometry; Hair; Heroin Dependence; Humans; Illicit Drugs; Marijuana Abuse; Morphine Derivatives; N-Methyl-3,4-methylenedioxyamphetamine; Opioid-Related Disorders; Psychotropic Drugs; Sensitivity and Specificity

1996
Acute poisoning with amphetamines (MDEA) and heroin: antagonistic effects between the two drugs.
    Intensive care medicine, 1996, Volume: 22, Issue:5

    Topics: 3,4-Methylenedioxyamphetamine; Acute Disease; Adult; Confusion; Critical Care; Designer Drugs; Drug Antagonism; Drug Monitoring; Heroin; Humans; Male; Narcotics; Suicide, Attempted; Time Factors

1996
[Acute fatal poisoning caused by methylenedioxyamphetamine].
    Medicina clinica, 1996, May-11, Volume: 106, Issue:18

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Designer Drugs; Fatal Outcome; Humans; Male

1996
Metabolism of racemic 3,4-methylenedioxyethylamphetamine in humans. Isolation, identification, quantification, and synthesis of urinary metabolites.
    Drug metabolism and disposition: the biological fate of chemicals, 1996, Volume: 24, Issue:8

    Topics: 3,4-Methylenedioxyamphetamine; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Humans; Magnetic Resonance Spectroscopy; Reference Values; Reproducibility of Results; Spectrophotometry, Infrared; Stereoisomerism

1996
Some examples of the analysis of complex samples by micellar electrokinetic capillary chromatography with photodiode array detection.
    Electrophoresis, 1996, Volume: 17, Issue:8

    Topics: 3,4-Methylenedioxyamphetamine; Alkaloids; Buffers; Chromatography, Liquid; Coloring Agents; Electrophoresis, Capillary; Micelles; Morphine; Spectrophotometry, Ultraviolet

1996
Toxicological detection of the designer drug 3,4-methylenedioxyethylamphetamine (MDE, "Eve") and its metabolites in urine by gas chromatography-mass spectrometry and fluorescence polarization immunoassay.
    Journal of chromatography. B, Biomedical applications, 1996, Aug-30, Volume: 683, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Administration, Oral; Amphetamines; Deoxyepinephrine; Designer Drugs; Dopamine; Fluorescence Polarization Immunoassay; Gas Chromatography-Mass Spectrometry; Hallucinogens; Humans; Time Factors

1996
Chronic ecstasy (3,4-methylenedioxymetamphetamine) abuse: a recurrent and unpredictable cause of severe acute hepatitis.
    Journal of hepatology, 1996, Volume: 25, Issue:4

    Topics: 3,4-Methylenedioxyamphetamine; Acute Disease; Adolescent; Adult; Biopsy; Chemical and Drug Induced Liver Injury; Female; Humans; Male; Recurrence; Substance-Related Disorders

1996
Quantitative and qualitative analysis of MDMA, MDEA, MA and amphetamine in urine by headspace/solid phase micro-extraction (SPME) and GC/MS.
    Forensic science international, 1996, Dec-27, Volume: 83, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Gas Chromatography-Mass Spectrometry; Hallucinogens; Humans; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine

1996
[Psychiatric disorders after a single 3,4-methylenedioxyethamphetamine (MDE, "Eve") and tetrahydrocannabinol (cannabis) use].
    Psychiatrische Praxis, 1996, Volume: 23, Issue:6

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Designer Drugs; Dronabinol; Drug Synergism; Female; Humans; Psychoses, Substance-Induced

1996
Hair analysis for drug abuse. XV. Disposition of 3, 4-methylenedioxymethamphetamine (MDMA) and its related compounds into rat hair and application to hair analysis for MDMA abuse.
    Forensic science international, 1997, Jan-17, Volume: 84, Issue:1-3

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Gas Chromatography-Mass Spectrometry; Hair; Hallucinogens; Humans; Lactates; Male; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Substance Abuse Detection; Substance-Related Disorders

1997
[Epidemiology of designer drug use in Spain].
    Medicina clinica, 1997, Jan-18, Volume: 108, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Adolescent; Adult; Cocaine; Designer Drugs; Female; Heroin; Humans; Male; N-Methyl-3,4-methylenedioxyamphetamine; Prevalence; Spain; Substance-Related Disorders

1997
Ecstasy: creatinine kinase.
    Anaesthesia and intensive care, 1997, Volume: 25, Issue:5

    Topics: 3,4-Methylenedioxyamphetamine; Creatine Kinase; Dantrolene; Designer Drugs; Fever; Humans; Multiple Organ Failure; Muscle Relaxants, Central; Muscle, Skeletal; N-Methyl-3,4-methylenedioxyamphetamine; Paraplegia

1997
Sensitive and selective determination of methylenedioxylated amphetamines by high-performance liquid chromatography with fluorimetric detection.
    Journal of chromatography. A, 1997, Nov-07, Volume: 787, Issue:1-2

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Chromatography, High Pressure Liquid; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Substance Abuse Detection; Tablets

1997
On acute poisoning with amphetamines.
    Intensive care medicine, 1998, Volume: 24, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Acute Disease; Designer Drugs; Heroin; Humans; Narcotic Antagonists; Narcotics; Substance-Related Disorders

1998
Ion trap mass spectrometry for the characterization of N-methyl-1- (3,4-methylene-dioxyphenyl)-2-butanamine and N-ethyl-3,4- methylenedioxyamphetamine, two widely distributed street drugs.
    Rapid communications in mass spectrometry : RCM, 1998, Volume: 12, Issue:12

    Topics: 3,4-Methylenedioxyamphetamine; Designer Drugs; Gas Chromatography-Mass Spectrometry; Illicit Drugs

1998
Intentional overdose and death with 3,4-methylenedioxyethamphetamine (MDEA; "Eve"): case report.
    The American journal of forensic medicine and pathology, 1998, Volume: 19, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Chromatography, Gas; Designer Drugs; Drug Overdose; Fatal Outcome; Female; Gas Chromatography-Mass Spectrometry; Humans; Suicide

1998
Detection of designer drugs in human hair by ion mobility spectrometry (IMS).
    Forensic science international, 1998, Jun-08, Volume: 94, Issue:1-2

    Topics: 3,4-Methylenedioxyamphetamine; Designer Drugs; Forensic Medicine; Hair; Hallucinogens; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Sensitivity and Specificity; Spectrometry, Mass, Secondary Ion; Substance-Related Disorders

1998
The acute effect in rats of 3,4-methylenedioxyethamphetamine (MDEA, "eve") on body temperature and long term degeneration of 5-HT neurones in brain: a comparison with MDMA ("ecstasy").
    Pharmacology & toxicology, 1999, Volume: 84, Issue:6

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Brain; Cerebral Cortex; Dose-Response Relationship, Drug; Fever; Hippocampus; Male; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Endings; Paroxetine; Rats; Serotonin; Time Factors; Visual Cortex

1999
Simultaneous determination of amphetamine, methamphetamine, methylenedioxyamphetamine (MDA), methylenedioxymethamphetamine (MDMA), and methylenedioxyethylamphetamine (MDEA) enantiomers by GC-MS.
    Journal of analytical toxicology, 1999, Volume: 23, Issue:6

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Central Nervous System Stimulants; Gas Chromatography-Mass Spectrometry; Humans; In Vitro Techniques; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Sensitivity and Specificity; Stereoisomerism; Substance Abuse Detection; Time Factors; Urine

1999
Adam (MDMA) and Eve (MDEA) misuse: an immunohistochemical study on three fatal cases.
    Forensic science international, 1999, Sep-30, Volume: 104, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Disseminated Intravascular Coagulation; Fatal Outcome; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Hallucinogens; Humans; Male; Myoglobinuria; N-Methyl-3,4-methylenedioxyamphetamine; Rhabdomyolysis

1999
Serotonergic deficits and impaired passive-avoidance learning in rats by MDEA: a comparison with MDMA.
    Pharmacology, biochemistry, and behavior, 2000, Volume: 65, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Avoidance Learning; Carrier Proteins; Designer Drugs; Frontal Lobe; Hippocampus; Male; Membrane Glycoproteins; Membrane Transport Proteins; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Tissue Proteins; Paroxetine; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Agents; Serotonin Plasma Membrane Transport Proteins

2000
The use of supercritical fluid extraction for the determination of amphetamines in hair.
    Forensic science international, 2000, Jan-10, Volume: 107, Issue:1-3

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Designer Drugs; Gas Chromatography-Mass Spectrometry; Hair; Humans; Illicit Drugs; N-Methyl-3,4-methylenedioxyamphetamine; Reference Values; Reproducibility of Results; Substance Abuse Detection; Substance-Related Disorders

2000
Automated determination of 'Ecstasy' and amphetamines in urine by SPME and capillary gas chromatography after propylchloroformate derivatisation.
    Journal of pharmaceutical and biomedical analysis, 1999, Volume: 19, Issue:3-4

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Designer Drugs; Esters; Evaluation Studies as Topic; Formates; Gas Chromatography-Mass Spectrometry; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Reproducibility of Results; Sensitivity and Specificity; Substance Abuse Detection

1999
High-resolution solid state 13C nuclear magnetic resonance spectra of 3,4-methylenedioxyamphetamine hydrochloride and related compounds and their mixtures with lactose.
    Solid state nuclear magnetic resonance, 2000, Volume: 16, Issue:4

    Topics: 3,4-Methylenedioxyamphetamine; Carbon Isotopes; Crystallization; Ephedrine; Hydrogen Bonding; Lactose; Magnetic Resonance Spectroscopy; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Solutions; Stereoisomerism

2000
Determination of the designer drugs 3, 4-methylenedioxymethamphetamine, 3,4-methylenedioxyethylamphetamine, and 3,4-methylenedioxyamphetamine with HPLC and fluorescence detection in whole blood, serum, vitreous humor, and urine.
    Clinical chemistry, 2000, Volume: 46, Issue:12

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Chromatography, High Pressure Liquid; Designer Drugs; Humans; Mass Spectrometry; N-Methyl-3,4-methylenedioxyamphetamine; Rabbits; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence; Substance Abuse Detection; Vitreous Body

2000
Identification of the nitrogen-based blister agents bis(2-chloroethyl)methylamine (HN-2) and tris(2-chloroethyl)amine (HN-3) and their hydrolysis products on soil using ion trap secondary ion mass spectrometry.
    Journal of mass spectrometry : JMS, 2000, Volume: 35, Issue:12

    Topics: 3,4-Methylenedioxyamphetamine; Chemical Warfare Agents; Ethanolamines; Hydrolysis; Irritants; Mechlorethamine; Nitrogen Mustard Compounds; Soil; Spectrometry, Mass, Secondary Ion

2000
Stereospecific analysis of ecstasy-like N-ethyl-3,4-methylenedioxyamphetamine and its metabolites in humans.
    Journal of chromatography. B, Biomedical sciences and applications, 2001, Feb-10, Volume: 751, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Chromatography, High Pressure Liquid; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Sensitivity and Specificity

2001
Alterations in diurnal and nocturnal locomotor activity in rats treated with a monoamine-depleting regimen of methamphetamine or 3,4-methylenedioxymethamphetamine.
    Psychopharmacology, 2001, Volume: 153, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Biogenic Monoamines; Circadian Rhythm; Dopamine Agents; Male; Methamphetamine; Motor Activity; Rats; Rats, Sprague-Dawley

2001
Danger: possibly fatal interactions between ritonavir and "ecstasy," some other psychoactive drugs.
    AIDS treatment news, 1997, Feb-21, Issue:No 265

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamine; Cocaine; Drug Interactions; Fatal Outcome; Hallucinogens; Heroin; HIV Protease Inhibitors; Humans; Illicit Drugs; Male; Methadone; Ritonavir

1997
Ecstasy and ritonavir.
    Treatment review, 1997, Issue:No 24

    Topics: 3,4-Methylenedioxyamphetamine; Analgesics, Opioid; Drug Interactions; Hallucinogens; HIV Protease Inhibitors; Humans; Male; Methadone; Ritonavir

1997
Behavioural, hyperthermic and neurotoxic effects of 3,4-methylenedioxymethamphetamine analogues in the Wistar rat.
    Progress in neuro-psychopharmacology & biological psychiatry, 2001, Volume: 25, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Biogenic Monoamines; Brain; Dopamine; Fever; Locomotion; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Wistar; Serotonin; Serotonin Agents

2001
Sensitive determination of methylenedioxylated amphetamines by liquid chromatography.
    The Analyst, 2001, Volume: 126, Issue:5

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Chromatography, Liquid; Hallucinogens; Humans; N-Methyl-3,4-methylenedioxyamphetamine

2001
Stability study of the designer drugs "MDA, MDMA and MDEA" in water, serum, whole blood, and urine under various storage temperatures.
    Forensic science international, 2001, Dec-15, Volume: 124, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Chromatography, High Pressure Liquid; Designer Drugs; Drug Stability; Drug Storage; Forensic Medicine; N-Methyl-3,4-methylenedioxyamphetamine; Reproducibility of Results; Water

2001
Application of SERS spectroscopy to the identification of (3,4-methylenedioxy)amphetamine in forensic samples utilizing matrix stabilized silver halides.
    The Analyst, 2001, Volume: 126, Issue:11

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamine; Illicit Drugs; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Spectrum Analysis, Raman

2001
Quantitation of amphetamine, methamphetamine, and their methylenedioxy derivatives in urine by solid-phase microextraction coupled with electrospray ionization-high-field asymmetric waveform ion mobility spectrometry-mass spectrometry.
    Analytical chemistry, 2002, Jul-01, Volume: 74, Issue:13

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamine; Central Nervous System Stimulants; Hallucinogens; Humans; Indicators and Reagents; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Spectrometry, Mass, Electrospray Ionization; Substance Abuse Detection

2002
Ecstasy counteracts catalepsy in rats, an anti-parkinsonian effect?
    Neuroscience letters, 2002, Sep-27, Volume: 330, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Adrenergic Uptake Inhibitors; Animals; Catalepsy; Dopamine Antagonists; Dose-Response Relationship, Drug; Haloperidol; Male; N-Methyl-3,4-methylenedioxyamphetamine; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley

2002
Developmental 3,4-methylenedioxymethamphetamine (MDMA) impairs sequential and spatial but not cued learning independent of growth, litter effects or injection stress.
    Brain research, 2003, Apr-04, Volume: 968, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Adrenocorticotropic Hormone; Aging; Animals; Animals, Newborn; Behavior, Animal; Body Constitution; Body Weight; Case-Control Studies; Corticosterone; Cues; Excitatory Amino Acid Agonists; Female; Learning Disabilities; Litter Size; Male; Maze Learning; Parity; Random Allocation; Rats; Rats, Sprague-Dawley; Reaction Time; Serial Learning; Sex Factors; Spatial Behavior; Stress, Physiological; Swimming; Time Factors

2003
Development of a rapid and sensitive method for the quantitation of amphetamines in human plasma and oral fluid by LC-MS-MS.
    Journal of analytical toxicology, 2003, Volume: 27, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamine; Amphetamines; Central Nervous System Stimulants; Chromatography, High Pressure Liquid; Chromatography, Liquid; Ephedrine; Humans; Mass Spectrometry; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Reproducibility of Results; Saliva; Substance Abuse Detection

2003
Is the Ecstasy-induced ipsilateral rotation in 6-hydroxydopamine unilaterally lesioned rats dopamine independent?
    Journal of neural transmission (Vienna, Austria : 1996), 2003, Volume: 110, Issue:7

    Topics: 3,4-Methylenedioxyamphetamine; Adrenergic Agents; Animals; Apomorphine; Behavior, Animal; Citalopram; Dopamine; Fenclonine; Functional Laterality; Hallucinogens; Male; Medial Forebrain Bundle; Models, Animal; N-Methyl-3,4-methylenedioxyamphetamine; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Rotation; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists

2003
Actions of amphetamine derivatives and cathinone at the noradrenaline transporter.
    European journal of pharmacology, 2003, Aug-22, Volume: 476, Issue:1-2

    Topics: 3,4-Methylenedioxyamphetamine; Adrenergic Uptake Inhibitors; Alkaloids; Amphetamines; Animals; Cerebral Cortex; Cocaine; Competitive Bidding; Fluoxetine; In Vitro Techniques; Male; Myocardium; N-Methyl-3,4-methylenedioxyamphetamine; Norepinephrine Plasma Membrane Transport Proteins; Rats; Rats, Wistar; Symporters

2003
Is ecstasy MDMA? A review of the proportion of ecstasy tablets containing MDMA, their dosage levels, and the changing perceptions of purity.
    Psychopharmacology, 2004, Volume: 173, Issue:3-4

    Topics: 3,4-Methylenedioxyamphetamine; Drug Combinations; Drug Contamination; Hallucinogens; History, 20th Century; History, 21st Century; Illicit Drugs; N-Methyl-3,4-methylenedioxyamphetamine; Tablets

2004
Application of ORAL.screen saliva drug test for the screening of methamphetamine, MDMA, and MDEA incorporated in hair.
    Journal of analytical toxicology, 2004, Volume: 28, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Forensic Medicine; Hair; Humans; Immunoassay; Immunochemistry; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Reagent Kits, Diagnostic; Saliva; Substance Abuse Detection

2004
Determination of MDMA, MDEA and MDA in urine by high performance liquid chromatography with fluorescence detection.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2004, Nov-05, Volume: 811, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Chromatography, High Pressure Liquid; Forensic Medicine; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence

2004
Enantiomeric separation and quantitation of (+/-)-amphetamine, (+/-)-methamphetamine, (+/-)-MDA, (+/-)-MDMA, and (+/-)-MDEA in urine specimens by GC-EI-MS after derivatization with (R)-(-)- or (S)-(+)-alpha-methoxy-alpha-(trifluoromethy)phenylacetyl chlor
    Journal of analytical toxicology, 2004, Volume: 28, Issue:6

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Chromatography, Gas; Chromatography, Ion Exchange; Humans; Indicators and Reagents; Methamphetamine; Military Personnel; N-Methyl-3,4-methylenedioxyamphetamine; Quaternary Ammonium Compounds; Reference Standards; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism; Substance Abuse Detection

2004
Prenatal 3,4-methylenedioxymethamphetamine (ecstasy) exposure induces long-term alterations in the dopaminergic and serotonergic functions in the rat.
    Brain research. Developmental brain research, 2005, Feb-08, Volume: 154, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; 3,4-Methylenedioxyamphetamine; Adrenergic Uptake Inhibitors; Age Factors; Analysis of Variance; Animals; Animals, Newborn; Autoradiography; Brain; Brain Chemistry; Dopamine; Embryo, Mammalian; Female; Fenfluramine; Hallucinogens; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Membrane Transport Proteins; Microdialysis; Nortropanes; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin; Sex Factors; Time Factors; Tyramine

2005
Amphetamine toxicity in the emergency department.
    European journal of emergency medicine : official journal of the European Society for Emergency Medicine, 2005, Volume: 12, Issue:4

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Amphetamines; Emergency Service, Hospital; Fatal Outcome; Female; Humans; Male; Substance-Related Disorders

2005
Drug testing in blood: validated negative-ion chemical ionization gas chromatographic-mass spectrometric assay for enantioselective measurement of the designer drugs MDEA, MDMA, and MDA and its application to samples from a controlled study with MDMA.
    Clinical chemistry, 2005, Volume: 51, Issue:10

    Topics: 3,4-Methylenedioxyamphetamine; Dose-Response Relationship, Drug; Gas Chromatography-Mass Spectrometry; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Sensitivity and Specificity; Stereoisomerism; Substance Abuse Detection; Time Factors

2005
An announced suicide with ecstasy.
    International journal of legal medicine, 2007, Volume: 121, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Austria; Autopsy; Drug Combinations; Drug Overdose; Forensic Toxicology; Humans; Male; N-Methyl-3,4-methylenedioxyamphetamine; Suicide

2007
LC-MS/MS in the elucidation of an isomer of the recreational drug methylenedioxy ethylamphetamine: methylenedioxy dimethylamphetamine.
    Journal of separation science, 2005, Volume: 28, Issue:14

    Topics: 3,4-Methylenedioxyamphetamine; Calibration; Chromatography, Liquid; Illicit Drugs; Indicators and Reagents; Isomerism; Mass Spectrometry; Models, Molecular; Molecular Structure; Spectrometry, Fluorescence

2005
Development and application of a high-performance liquid chromatography method using monolithic columns for the analysis of ecstasy tablets.
    Journal of chromatography. A, 2006, Jul-07, Volume: 1120, Issue:1-2

    Topics: 3,4-Methylenedioxyamphetamine; Chromatography, High Pressure Liquid; Hallucinogens; N-Methyl-3,4-methylenedioxyamphetamine; Reference Standards; Reproducibility of Results; Spectrophotometry, Ultraviolet; Tablets; Technology, Pharmaceutical

2006
Effects of MDMA, MDA and MDEA on blood pressure, heart rate, locomotor activity and body temperature in the rat involve alpha-adrenoceptors.
    British journal of pharmacology, 2006, Volume: 147, Issue:8

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Aorta; Blood Pressure; Body Temperature; Heart Rate; Imidazoles; Indoles; Isoindoles; Male; Motor Activity; Muscle Contraction; Muscle, Smooth; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Time Factors; Vas Deferens

2006
Ecstasy (MDMA, MDA, MDEA, MBDB) consumption, seizures, related offences, prices, dosage levels and deaths in the UK (1994-2003).
    Journal of psychopharmacology (Oxford, England), 2006, Volume: 20, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamine-Related Disorders; Cause of Death; Crime; Cross-Sectional Studies; Dose-Response Relationship, Drug; Drug and Narcotic Control; Humans; Illicit Drugs; N-Methyl-3,4-methylenedioxyamphetamine; Statistics as Topic; United Kingdom

2006
Chiral separation and quantification of R/S-amphetamine, R/S-methamphetamine, R/S-MDA, R/S-MDMA, and R/S-MDEA in whole blood by GC-EI-MS.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2006, Oct-02, Volume: 842, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamine; Chromatography, Gas; Humans; Methamphetamine; Molecular Structure; N-Methyl-3,4-methylenedioxyamphetamine; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism; Substance Abuse Detection

2006
Clozapine reverses increased brown adipose tissue thermogenesis induced by 3,4-methylenedioxymethamphetamine and by cold exposure in conscious rats.
    Neuroscience, 2006, Sep-15, Volume: 141, Issue:4

    Topics: 3,4-Methylenedioxyamphetamine; Adipose Tissue, Brown; Animals; Body Temperature; Clozapine; Cold Temperature; Consciousness; GABA Antagonists; Intestines; Male; Rats; Rats, Sprague-Dawley; Thermogenesis; Time Factors

2006
Sensitive gas chromatography-mass spectrometry method for simultaneous measurement of MDEA, MDMA, and metabolites HMA, MDA, and HMMA in human urine.
    Clinical chemistry, 2006, Volume: 52, Issue:9

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Calibration; Central Nervous System Stimulants; Dopamine; Gas Chromatography-Mass Spectrometry; Humans; Hydrolysis; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Sensitivity and Specificity; Substance Abuse Detection

2006
Time-resolved hair analysis of MDMA enantiomers by GC/MS-NCI.
    Forensic science international, 2007, Oct-25, Volume: 172, Issue:2-3

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamine; Biomarkers; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Gas Chromatography-Mass Spectrometry; Hair; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Substance Abuse Detection; Time Factors

2007
Analysis of MDMA and its metabolites in urine and plasma following a neurotoxic dose of MDMA.
    Journal of analytical toxicology, 2007, Volume: 31, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Biotransformation; Calibration; Dopamine; Gas Chromatography-Mass Spectrometry; Male; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Psychotropic Drugs; Rats; Reproducibility of Results; Toxicology

2007
Simultaneous analysis of six amphetamines and analogues in hair, blood and urine by LC-ESI-MS/MS. Application to the determination of MDMA after low ecstasy intake.
    Forensic science international, 2007, Aug-06, Volume: 170, Issue:2-3

    Topics: 3,4-Methylenedioxyamphetamine; Adolescent; Amphetamines; Chromatography, Liquid; Female; Forensic Toxicology; Hair; Hallucinogens; Humans; Spectrometry, Mass, Electrospray Ionization; Substance Abuse Detection

2007
Validated liquid chromatographic-electrospray ionization mass spectrometric assay for simultaneous determination of 3,4-methylenedioxymethamphetamine and its metabolites 3,4-methylenedioxyamphetamine, 3,4-dihydroxymethamphetamine, and 4-hydroxy-3-methoxym
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2007, Aug-15, Volume: 855, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Calibration; Chromatography, Liquid; Deoxyepinephrine; Hallucinogens; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Saimiri; Spectrometry, Mass, Electrospray Ionization

2007
Two-dimensional gas chromatography/electron-impact mass spectrometry with cryofocusing for simultaneous quantification of MDMA, MDA, HMMA, HMA, and MDEA in human plasma.
    Clinical chemistry, 2008, Volume: 54, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Calibration; Central Nervous System Stimulants; Dopamine; Gas Chromatography-Mass Spectrometry; Humans; Hydrolysis; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Reproducibility of Results; Substance Abuse Detection

2008
The effect of long-term repeated exposure to 3,4-methylenedioxymethamphetamine on cardiovascular and thermoregulatory changes.
    Psychopharmacology, 2008, Volume: 201, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; 3,4-Methylenedioxyamphetamine; Animals; Behavior, Animal; Body Temperature Regulation; Cerebral Cortex; Dopamine; Dose-Response Relationship, Drug; Drug Administration Schedule; Heart Rate; Hot Temperature; Humans; Hydroxyindoleacetic Acid; Hyperthermia, Induced; Injections, Intraperitoneal; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Serotonin; Telemetry; Time Factors

2008
Impact of plasticity and flexibility on docking results for cytochrome P450 2D6: a combined approach of molecular dynamics and ligand docking.
    Journal of medicinal chemistry, 2008, Dec-11, Volume: 51, Issue:23

    Topics: 3,4-Methylenedioxyamphetamine; Catalytic Domain; Chlorpromazine; Computer Simulation; Coumarins; Cytochrome P-450 CYP2D6; Ligands; Models, Chemical; Molecular Structure; Propranolol; Stereoisomerism; Tamoxifen

2008
Simultaneous determination of methamphetamine, 3,4-methylenedioxy-N-methylamphetamine, 3,4-methylenedioxy-N-ethylamphetamine, N,N-dimethylamphetamine, and their metabolites in urine by liquid chromatography-electrospray ionization-tandem mass spectrometry
    Archives of pharmacal research, 2008, Volume: 31, Issue:12

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Chromatography, High Pressure Liquid; Humans; Hydrogen-Ion Concentration; Indicators and Reagents; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization

2008
The role of human hepatic cytochrome P450 isozymes in the metabolism of racemic 3,4-methylenedioxyethylamphetamine and its single enantiomers.
    Drug metabolism and disposition: the biological fate of chemicals, 2009, Volume: 37, Issue:6

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamine; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Designer Drugs; Gas Chromatography-Mass Spectrometry; Humans; Isoenzymes; Microsomes, Liver; Stereoisomerism; Substrate Specificity

2009
Determination of the metabolites of the new designer drugs bk-MBDB and bk-MDEA in human urine.
    Forensic science international, 2009, Jul-01, Volume: 188, Issue:1-3

    Topics: 3,4-Methylenedioxyamphetamine; Designer Drugs; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Hallucinogens; Humans; Hydrolysis; Methylation

2009
Enantioselectivity in the methylation of the catecholic phase I metabolites of methylenedioxy designer drugs and their capability to inhibit catechol-O-methyltransferase-catalyzed dopamine 3-methylation.
    Chemical research in toxicology, 2009, Volume: 22, Issue:6

    Topics: 3,4-Methylenedioxyamphetamine; Biocatalysis; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Catechols; Cytochrome P-450 Enzyme System; Designer Drugs; Dopamine; Enzyme Inhibitors; Gas Chromatography-Mass Spectrometry; Humans; Kinetics; Methylation; Microsomes, Liver; N-Methyl-3,4-methylenedioxyamphetamine; Stereoisomerism

2009
Urinary MDMA, MDA, HMMA, and HMA excretion following controlled MDMA administration to humans.
    Journal of analytical toxicology, 2009, Volume: 33, Issue:8

    Topics: 3,4-Methylenedioxyamphetamine; Adolescent; Adult; Female; Gas Chromatography-Mass Spectrometry; Hallucinogens; Humans; Male; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Substance Abuse Detection; Young Adult

2009
Role of water in molecular docking simulations of cytochrome P450 2D6.
    Journal of chemical information and modeling, 2010, Volume: 50, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Catalytic Domain; Cytochrome P-450 CYP2D6; Molecular Dynamics Simulation; Reproducibility of Results; Water

2010
GC-MS studies on side chain regioisomers related to substituted methylenedioxyphenethylamines: MDEA, MDMMA, and MBDB.
    Journal of chromatographic science, 2010, Volume: 48, Issue:9

    Topics: 3,4-Methylenedioxyamphetamine; Gas Chromatography-Mass Spectrometry; Illicit Drugs; Molecular Conformation; Molecular Weight; Stereoisomerism

2010
Hair MDMA samples are consistent with reported ecstasy use: findings from a study investigating effects of ecstasy on mood and memory.
    Neuropsychobiology, 2011, Volume: 63, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Adolescent; Adult; Affect; Female; Hair; Humans; Illicit Drugs; Internet; Male; Marijuana Smoking; Memory; Self Medication; Self Report; Substance Abuse Detection; Surveys and Questionnaires

2011
Differences in binding affinities of MDA, MDMA, MDEA, Amphetamine, Methamphetamine, and their deuterated analogues to solid-phase extraction cartridges.
    Journal of analytical toxicology, 2011, Volume: 35, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamine; Deuterium; Gas Chromatography-Mass Spectrometry; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Solid Phase Extraction; Substance Abuse Detection

2011
Inhibition of 3,4-methylenedioxymethamphetamine metabolism leads to marked decrease in 3,4-dihydroxymethamphetamine formation but no change in serotonin neurotoxicity: implications for mechanisms of neurotoxicity.
    Synapse (New York, N.Y.), 2011, Volume: 65, Issue:10

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Deoxyepinephrine; Dextromethorphan; Excitatory Amino Acid Antagonists; Hydroxyindoleacetic Acid; Male; Neurotoxicity Syndromes; Neurotoxins; Rats; Rats, Sprague-Dawley; Serotonin; Sulfides

2011
Simultaneous determination of HFBA-derivatized amphetamines and ketamines in urine by gas chromatography-mass spectrometry.
    Journal of analytical toxicology, 2011, Volume: 35, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Fluorocarbons; Gas Chromatography-Mass Spectrometry; Humans; Illicit Drugs; Ketamine; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Solid Phase Extraction; Substance Abuse Detection

2011
A comparison of the validity of gas chromatography-mass spectrometry and liquid chromatography-tandem mass spectrometry analysis of urine samples II: amphetamine, methamphetamine, (±)-3,4-methylenedioxyamphetamine, (±)-3,4-methylenedioxymethamphetamine, (
    Journal of analytical toxicology, 2010, Volume: 34, Issue:8

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamine; Chromatography, High Pressure Liquid; Dronabinol; Gas Chromatography-Mass Spectrometry; Illicit Drugs; Methamphetamine; Phencyclidine; Reproducibility of Results; Substance Abuse Detection; Tandem Mass Spectrometry

2010
Molecularly imprinted solid-phase extraction for the selective determination of methamphetamine, amphetamine, and methylenedioxyphenylalkylamine designer drugs in human whole blood by gas chromatography-mass spectrometry.
    Journal of separation science, 2012, Volume: 35, Issue:5-6

    Topics: 3,4-Methylenedioxyamphetamine; Adsorption; Amphetamine; Amphetamines; Designer Drugs; Gas Chromatography-Mass Spectrometry; Humans; Molecular Imprinting; Polymers; Solid Phase Extraction

2012
New chlorinated amphetamine-type-stimulants disinfection-by-products formed during drinking water treatment.
    Water research, 2012, Jun-15, Volume: 46, Issue:10

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Central Nervous System Stimulants; Disinfection; Drinking Water; Halogenation; N-Methyl-3,4-methylenedioxyamphetamine; Spain; Spectrometry, Mass, Electrospray Ionization; Water Purification; Water Quality

2012
Investigations on the stereoselectivity of the phase II metabolism of the 3,4-methylenedioxyethylamphetamine (MDEA) metabolites 3,4-dihydroxyethylamphetamine (DHEA) and 4-hydroxy-3-methoxyethylamphetamine (HMEA).
    Toxicology letters, 2012, Jul-07, Volume: 212, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Designer Drugs; Gas Chromatography-Mass Spectrometry; Humans; Liver; Microsomes, Liver; Rats; Stereoisomerism; Sulfotransferases

2012
Effects of stress and MDMA on hippocampal gene expression.
    BioMed research international, 2014, Volume: 2014

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Gene Expression Regulation; Hippocampus; Neurotoxicity Syndromes; Protein Biosynthesis; Protein Folding; Rats; Serotonin; Serotonin Agents; Stress Disorders, Post-Traumatic

2014
Molecular basis of the selective binding of MDMA enantiomers to the alpha4beta2 nicotinic receptor subtype: synthesis, pharmacological evaluation and mechanistic studies.
    European journal of medicinal chemistry, 2014, Jun-23, Volume: 81

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Binding Sites; Dose-Response Relationship, Drug; Molecular Structure; PC12 Cells; Rats; Receptors, Nicotinic; Stereoisomerism; Structure-Activity Relationship

2014
Amiodarone and metabolite MDEA inhibit Ebola virus infection by interfering with the viral entry process.
    Pathogens and disease, 2015, Volume: 73, Issue:5

    Topics: 3,4-Methylenedioxyamphetamine; Amiodarone; Animals; Antiviral Agents; Cell Line; Ebolavirus; Humans; Microbial Sensitivity Tests; Virus Internalization

2015
Screening for illicit drugs in pooled human urine and urinated soil samples and studies on the stability of urinary excretion products of cocaine, MDMA, and MDEA in wastewater by hyphenated mass spectrometry techniques.
    Drug testing and analysis, 2017, Volume: 9, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Adrenergic Uptake Inhibitors; Cocaine; Dopamine Uptake Inhibitors; Environmental Pollutants; Humans; Illicit Drugs; Limit of Detection; N-Methyl-3,4-methylenedioxyamphetamine; Soil; Substance Abuse Detection; Wastewater

2017
Tunability of Biodegradable Poly(amine- co-ester) Polymers for Customized Nucleic Acid Delivery and Other Biomedical Applications.
    Biomacromolecules, 2018, 09-10, Volume: 19, Issue:9

    Topics: 3,4-Methylenedioxyamphetamine; 3T3 Cells; Animals; Decanoic Acids; Dicarboxylic Acids; Esters; Gene Transfer Techniques; HEK293 Cells; Humans; Macrolides; Mice; Nanoparticles; Polyamines; Polymerization

2018
A Gas Chromatography-Mass Spectrometry Method for Toxicological Analysis of MDA, MDEA and MDMA in Vitreous Humor Samples from Victims of Car Accidents.
    Journal of analytical toxicology, 2018, Nov-01, Volume: 42, Issue:9

    Topics: 3,4-Methylenedioxyamphetamine; Accidents, Traffic; Driving Under the Influence; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; Limit of Detection; N-Methyl-3,4-methylenedioxyamphetamine; Postmortem Changes; Reproducibility of Results; Vitreous Body

2018
Emergency Embolization of Artery of Adamkiewicz Pseudoaneurysm Following Methylenedioxymethamphetamine Abuse.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2019, Volume: 46, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Aneurysm, False; Arteries; Computed Tomography Angiography; Embolization, Therapeutic; Humans; Magnetic Resonance Imaging; Male; Subarachnoid Hemorrhage; Substance-Related Disorders; Tomography Scanners, X-Ray Computed

2019
Serotonin syndrome unmasking thyrotoxicosis.
    BMJ case reports, 2019, Mar-07, Volume: 12, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Aftercare; Anti-Arrhythmia Agents; Antithyroid Agents; Carbimazole; Delirium; Diagnosis, Differential; Humans; Intensive Care Units; Male; Propranolol; Serotonin Syndrome; Substance-Related Disorders; Thyrotoxicosis; Thyrotropin; Treatment Outcome; Tremor

2019
[High-risk drug use: epidemiological pattern through hair testing in the forensic context].
    Revista espanola de salud publica, 2019, Nov-26, Volume: 93

    Topics: 3,4-Methylenedioxyamphetamine; Adolescent; Adult; Amphetamine; Cannabinoids; Cocaine; Cross-Sectional Studies; Female; Forensic Sciences; Gas Chromatography-Mass Spectrometry; Hair; Heroin; Humans; Illicit Drugs; Ketamine; Male; Methadone; Methamphetamine; Middle Aged; N-Methyl-3,4-methylenedioxyamphetamine; Prevalence; Spain; Substance Abuse Detection; Substance-Related Disorders; Young Adult

2019
Interaction Profiles of Central Nervous System Active Drugs at Human Organic Cation Transporters 1-3 and Human Plasma Membrane Monoamine Transporter.
    International journal of molecular sciences, 2021, Nov-30, Volume: 22, Issue:23

    Topics: 3,4-Methylenedioxyamphetamine; Cell Line; Central Nervous System; Citalopram; Dopamine Plasma Membrane Transport Proteins; Equilibrative Nucleoside Transport Proteins; GABA Plasma Membrane Transport Proteins; HEK293 Cells; Humans; Octamer Transcription Factors; Organic Cation Transporter 1; Organic Cation Transporter 2; Psychotropic Drugs; Pyrrolidines; Serotonin Plasma Membrane Transport Proteins; Vesicular Monoamine Transport Proteins

2021
CO
    Environmental science and pollution research international, 2022, Volume: 29, Issue:25

    Topics: 3,4-Methylenedioxyamphetamine; Carbon Dioxide; Ethanolamines; Thiophenes; Water

2022