3,4-epoxybutane-1,2-diol has been researched along with diepoxybutane in 13 studies
Studies (3,4-epoxybutane-1,2-diol) | Trials (3,4-epoxybutane-1,2-diol) | Recent Studies (post-2010) (3,4-epoxybutane-1,2-diol) | Studies (diepoxybutane) | Trials (diepoxybutane) | Recent Studies (post-2010) (diepoxybutane) |
---|---|---|---|---|---|
26 | 0 | 3 | 382 | 3 | 39 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 6 (46.15) | 18.2507 |
2000's | 6 (46.15) | 29.6817 |
2010's | 1 (7.69) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Lähdetie, J; Sjöblom, T | 1 |
Lähdetie, J; Peltonen, K; Sjöblom, T | 1 |
Grawé, J; Lähdetie, J | 1 |
Kilpeläinen, I; Koivisto, P; Lähdetie, J; Landin, H; Osterman-Golkar, S; Peltonen, K; Pérez, HL | 1 |
Adler, ID; Kliesch, U; Nylund, L; Peltonen, K | 1 |
Adler, ID; Kilpeläinen, I; Koivisto, P; Pacchierotti, F; Peltonen, K; Rasanen, I | 1 |
Jackson, MA; Rice, JM; Stack, HF; Waters, MD | 1 |
Erexson, GL; Tindall, KR | 1 |
Bhowmik, S; Csanády, GA; Faller, TH; Filser, JG; Kessler, W; Pütz, C; Schuster, A | 1 |
Kim, HJ; Kim, TH; Lee, CS; Lee, DH; Lee, SY; Pfeifer, GP; Rhee, SK; Yoon, B | 1 |
Csanády, GA; Filser, JG; Hutzler, C; Meischner, V; Veereshwarayya, V | 1 |
Bois, FY; Brochot, C; Smith, TJ | 1 |
An, J; Wen, Y; Wu, MH; Yu, YX; Zhang, PP; Zhang, XY | 1 |
1 review(s) available for 3,4-epoxybutane-1,2-diol and diepoxybutane
Article | Year |
---|---|
A review of the genetic and related effects of 1,3-butadiene in rodents and humans.
Topics: Air Pollutants, Occupational; Alkylating Agents; Animals; Aryl Hydrocarbon Hydroxylases; Biomarkers; Biotransformation; Butadienes; Carcinogens; Cytochrome P-450 CYP2A6; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; DNA; DNA Adducts; DNA Damage; Epoxy Compounds; Female; Glycols; Hemoglobins; Humans; Inactivation, Metabolic; Male; Mice; Mice, Inbred C57BL; Mixed Function Oxygenases; Mutagenesis; Mutagenicity Tests; Mutagens; Neoplasms, Experimental; Occupational Exposure; Organ Specificity; Oxidation-Reduction; Proteins; Rats; Rats, Sprague-Dawley; Single-Blind Method; Sister Chromatid Exchange; Species Specificity | 2000 |
12 other study(ies) available for 3,4-epoxybutane-1,2-diol and diepoxybutane
Article | Year |
---|---|
Micronuclei are induced in rat spermatids in vitro by 1,2,3,4-diepoxybutane but not by 1,2-epoxy-3-butene and 1,2-dihydroxy-3,4-epoxybutane.
Topics: Animals; Butadienes; Dose-Response Relationship, Drug; Epoxy Compounds; Glycols; Male; Meiosis; Micronucleus Tests; Mutagens; Rats; Rats, Sprague-Dawley; Spermatids | 1996 |
Germ cell mutagenicity of three metabolites of 1,3-butadiene in the rat: induction of spermatid micronuclei by butadiene mono-, di-, and diolepoxides in vivo.
Topics: Animals; Body Weight; Butadienes; Cell Survival; DNA Replication; Epoxy Compounds; Glycols; Male; Micronucleus Tests; Mutagens; Organ Size; Rats; Rats, Sprague-Dawley; Spermatids; Testis | 1997 |
Flow cytometric analysis of micronucleus induction in rat bone marrow polychromatic erythrocytes by 1,2;3,4-diepoxybutane, 3,4-epoxy-1-butene, and 1,2-epoxybutane-3,4-diol.
Topics: Animals; Benzimidazoles; Bone Marrow Cells; Cell Separation; Epoxy Compounds; Erythrocyte Aging; Erythrocytes; Flow Cytometry; Fluorescent Dyes; Glycols; Male; Mice; Micronucleus Tests; Mutagens; Rats; Rats, Sprague-Dawley | 1997 |
Haemoglobin adducts of epoxybutanediol from exposure to 1,3-butadiene or butadiene epoxides.
Topics: Air Pollutants, Occupational; Animals; Butadienes; Epoxy Compounds; Gas Chromatography-Mass Spectrometry; Glycols; Hemoglobins; Humans; Magnetic Resonance Spectroscopy; Male; Micronucleus Tests; Rats; Rats, Sprague-Dawley; Rats, Wistar; Valine | 1997 |
In vitro and in vivo mutagenicity of the butadiene metabolites butadiene diolepoxide, butadiene monoepoxide and diepoxybutane.
Topics: Animals; Bone Marrow Cells; Butadienes; Crosses, Genetic; Epoxy Compounds; Female; Fetal Death; Genes, Lethal; Glycols; Litter Size; Male; Mice; Mice, Inbred C3H; Mice, Inbred Strains; Micronucleus Tests; Mutagenicity Tests; Mutagens; Pregnancy; Salmonella typhimurium; Structure-Activity Relationship | 1997 |
Butadiene diolepoxide- and diepoxybutane-derived DNA adducts at N7-guanine: a high occurrence of diolepoxide-derived adducts in mouse lung after 1,3-butadiene exposure.
Topics: Animals; Butadienes; Cell Line; Chromatography, High Pressure Liquid; DNA Adducts; Dose-Response Relationship, Drug; Epoxy Compounds; Glycols; Guanine; Humans; Inhalation Exposure; Lung; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mice; Molecular Conformation; Molecular Structure; Phosphorus Radioisotopes | 1999 |
Micronuclei and gene mutations in transgenic big Blue((R)) mouse and rat fibroblasts after exposure to the epoxide metabolites of 1, 3-butadiene.
Topics: Analysis of Variance; Animals; Animals, Genetically Modified; Apoptosis; Biotransformation; Butadienes; Cell Survival; Cells, Cultured; Epoxy Compounds; Fibroblasts; Glycols; Humans; Mice; Mice, Transgenic; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mutagenicity Tests; Rats; Rats, Mutant Strains | 2000 |
First-pass metabolism of 1,3-butadiene in once-through perfused livers of rats and mice.
Topics: Aldehydes; Animals; Biotransformation; Butadienes; Epoxy Compounds; Glycols; Kinetics; Liver; Male; Mice; Perfusion; Rats; Rats, Sprague-Dawley; Species Specificity | 2001 |
Mutations induced by 1,3-butadiene metabolites, butadiene diolepoxide, and 1,2,3,4-diepoxybutane at the Hprt locus in CHO-K1 cells.
Topics: Animals; Butadienes; Carcinogens; Cell Survival; CHO Cells; Cricetinae; DNA Adducts; DNA Damage; DNA Mutational Analysis; DNA Primers; Epoxy Compounds; Exons; Formazans; Glycols; Hypoxanthine Phosphoribosyltransferase; Mutagenesis; Mutagens; Mutation; Polymerase Chain Reaction; Sequence Deletion; Tetrazolium Salts | 2002 |
Metabolism of 1,3-butadiene to toxicologically relevant metabolites in single-exposed mice and rats.
Topics: Animals; Biotransformation; Butadienes; Epoxy Compounds; Glycols; Inhalation Exposure; Male; Mice; Rats; Rats, Sprague-Dawley; Time Factors | 2007 |
Development of a physiologically based toxicokinetic model for butadiene and four major metabolites in humans: global sensitivity analysis for experimental design issues.
Topics: Administration, Inhalation; Adult; Biotransformation; Body Fluid Compartments; Breath Tests; Butadienes; Butylene Glycols; Epoxy Compounds; Glycols; Humans; Kinetics; Male; Models, Biological; Reference Values; Sensitivity and Specificity; Software; Time Factors | 2007 |
DNA damage induced by three major metabolites of 1,3-butadiene in human hepatocyte L02 cells.
Topics: Butadienes; Butylene Glycols; Carcinogens; Cell Line, Transformed; Comet Assay; DNA Breaks, Single-Stranded; DNA Damage; Epoxy Compounds; Hepatocytes; Humans; Mutagens | 2012 |