Page last updated: 2024-08-26

3,4-epoxy-3-methyl-1-butene and isoprene

3,4-epoxy-3-methyl-1-butene has been researched along with isoprene in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's4 (66.67)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bogaards, JJ; van Bladeren, PJ; Venekamp, JC1
Amato, G; Chiappe, C; De Rubertis, A; Gervasi, PG; Tinagli, V1
Bogaards, JJ; Freidig, AP; van Bladeren, PJ1
Fred, C; Grawé, J; Törnqvist, M1
De Bartolomeo, A; Fabiani, R; Fuccelli, R; Morozzi, G; Rosignoli, P1
Begemann, P; Boysen, G; Georgieva, NI; Gold, A; Golding, BT; Koc, H; Koshlap, KM; Sangaiah, R; Swenberg, JA; Zhang, D1

Other Studies

6 other study(ies) available for 3,4-epoxy-3-methyl-1-butene and isoprene

ArticleYear
The biotransformation of isoprene and the two isoprene monoepoxides by human cytochrome P450 enzymes, compared to mouse and rat liver microsomes.
    Chemico-biological interactions, 1996, Dec-20, Volume: 102, Issue:3

    Topics: Animals; Biotransformation; Butadienes; Cyclohexanes; Cyclohexenes; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Epoxide Hydrolases; Epoxy Compounds; Hemiterpenes; Humans; Hydrolysis; Mice; Microsomes, Liver; Oxidation-Reduction; Pentanes; Rats; Rats, Wistar; Species Specificity

1996
Stereochemical course of the biotransformation of isoprene monoepoxides and of the corresponding diols with liver microsomes from control and induced rats.
    Chemical research in toxicology, 2000, Volume: 13, Issue:9

    Topics: Animals; Biotransformation; Butadienes; Chromatography, Gas; Cytochrome P-450 Enzyme System; Enzyme Induction; Epoxy Compounds; Hemiterpenes; Male; Microsomes, Liver; Pentanes; Phenobarbital; Pyrenes; Rats; Rats, Sprague-Dawley; Stereoisomerism

2000
Prediction of isoprene diepoxide levels in vivo in mouse, rat and man using enzyme kinetic data in vitro and physiologically-based pharmacokinetic modelling.
    Chemico-biological interactions, 2001, Dec-21, Volume: 138, Issue:3

    Topics: Animals; Butadienes; Cytochrome P-450 Enzyme System; Epoxide Hydrolases; Epoxy Compounds; Glutathione Transferase; Hemiterpenes; Humans; Mice; Mice, Inbred Strains; Microsomes, Liver; Models, Biological; Pentanes; Rats; Rats, Wistar; Species Specificity

2001
Hemoglobin adducts and micronuclei in rodents after treatment with isoprene monoxide or butadiene monoxide.
    Mutation research, 2005, Aug-01, Volume: 585, Issue:1-2

    Topics: Animals; Bone Marrow Cells; Butadienes; Cells, Cultured; Dose-Response Relationship, Drug; Epoxy Compounds; Erythrocytes; Hemiterpenes; Hemoglobins; Male; Mice; Mice, Inbred C57BL; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mutagens; Pentanes; Rats; Rats, Sprague-Dawley

2005
DNA-damaging ability of isoprene and isoprene mono-epoxide (EPOX I) in human cells evaluated with the comet assay.
    Mutation research, 2007, Apr-20, Volume: 629, Issue:1

    Topics: Animals; Butadienes; Carcinogens; Cell Survival; Cells, Cultured; Comet Assay; DNA Damage; Dose-Response Relationship, Drug; Epoxy Compounds; Hemiterpenes; HL-60 Cells; Humans; Kinetics; Leukocytes, Mononuclear; Microsomes, Liver; Pentanes; Rats; Structure-Activity Relationship

2007
Identification and characterization of 2'-deoxyadenosine adducts formed by isoprene monoepoxides in vitro.
    Chemical research in toxicology, 2011, Jul-18, Volume: 24, Issue:7

    Topics: Butadienes; Chromatography, High Pressure Liquid; Deoxyadenosines; DNA Adducts; Epoxy Compounds; Hemiterpenes; Magnetic Resonance Spectroscopy; Pentanes; Tandem Mass Spectrometry

2011