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3,4-epoxy-1-butene and guanine

3,4-epoxy-1-butene has been researched along with guanine in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19901 (9.09)18.7374
1990's6 (54.55)18.2507
2000's4 (36.36)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bellucci, G; Bianchini, R; Citti, L; Gervasi, PG; Turchi, G1
Kaltia, S; Koivisto, P; Kostiainen, R; Neagu, C; Neagu, I; Peltonen, K1
Adler, ID; Koivisto, P; Peltonen, K; Sorsa, M1
Lin, YP; Sangaiah, R; Swenberg, JA; Upton, PB1
Lin, Y; Sangaiah, R; Swenberg, JA; Tretyakova, N; Upton, PB1
Adler, ID; Koivisto, P; Pacchierotti, F; Peltonen, K1
Elfarra, AA; Selzer, RR1
Carmical, JR; Harris, CM; Harris, TM; Lloyd, RS; Nechev, L; Zhang, M1
Harris, CM; Harris, TM; Nechev, LV; Tamura, PJ; Tsarouhtsis, D; Wilkinson, AS; Zhang, M1
Booth, ED; Kilgour, JD; Robinson, SA; Watson, WP1
Boogaard, PJ; Booth, ED; de Kloe, KP; Watson, WP1

Other Studies

11 other study(ies) available for 3,4-epoxy-1-butene and guanine

ArticleYear
The reaction of 3,4-epoxy-1-butene with deoxyguanosine and DNA in vitro: synthesis and characterization of the main adducts.
    Carcinogenesis, 1984, Volume: 5, Issue:1

    Topics: Apurinic Acid; Chemical Phenomena; Chemistry; Deoxyguanosine; DNA; Epoxy Compounds; Ethers, Cyclic; Guanine; Mass Spectrometry

1984
Alkylation of purine bases with 3,4-epoxy-1-butene, a reactive metabolite of 1,3-butadiene.
    IARC scientific publications, 1994, Issue:125

    Topics: Adenine; Alkylation; Butadienes; Chromatography, High Pressure Liquid; DNA; DNA Adducts; Electrochemistry; Epoxy Compounds; Guanine; Heating; Hydrolysis; Magnetic Resonance Spectroscopy; Mutagens; Purines; Sensitivity and Specificity

1994
Inhalation exposure of rats and mice to 1,3-butadiene induces N6-adenine adducts of epoxybutene detected by 32P-postlabeling and HPLC.
    Environmental health perspectives, 1996, Volume: 104 Suppl 3

    Topics: Adenine; Administration, Inhalation; Alkylation; Animals; Butadienes; Cattle; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; DNA Adducts; Epoxy Compounds; Guanine; In Vitro Techniques; Mice; Phosphorus Radioisotopes; Rats

1996
Macromolecular adducts of butadiene.
    Toxicology, 1996, Oct-28, Volume: 113, Issue:1-3

    Topics: Adenine; Animals; Butadienes; DNA; Epoxy Compounds; Female; Globins; Guanine; Guanosine; Humans; Male; Mice; Rats; Species Specificity

1996
Identification and quantitation of DNA adducts from calf thymus DNA exposed to 3,4-epoxy-1-butene.
    Carcinogenesis, 1997, Volume: 18, Issue:1

    Topics: Adenine; Animals; Cattle; DNA Adducts; Epoxy Compounds; Guanine; Guanosine; Mutagens

1997
DNA adducts in mouse testis and lung after inhalation exposure to 1,3-butadiene.
    Mutation research, 1998, Jan-16, Volume: 397, Issue:1

    Topics: Alkylation; Animals; Biomarkers; Butadienes; Chromatography, High Pressure Liquid; DNA Adducts; DNA Repair; Environmental Pollution; Epoxy Compounds; Germ Cells; Guanine; Lung; Male; Mice; Molecular Structure; Mutagens; Stereoisomerism; Testis

1998
In vitro reactions of butadiene monoxide with single- and double-stranded DNA: characterization and quantitation of several purine and pyrimidine adducts.
    Carcinogenesis, 1999, Volume: 20, Issue:2

    Topics: Adenine; Alkylation; Deoxyadenosines; Deoxyguanosine; Deoxyuridine; DNA; DNA Adducts; DNA, Single-Stranded; Dose-Response Relationship, Drug; Epoxy Compounds; Guanine; Mutagens; Purines; Pyrimidines

1999
Mutagenic potential of guanine N2 adducts of butadiene mono- and diolepoxide.
    Chemical research in toxicology, 2000, Volume: 13, Issue:1

    Topics: Base Sequence; Butadienes; Codon; DNA Adducts; DNA Replication; DNA-Directed DNA Polymerase; DNA, Circular; Epoxy Compounds; Escherichia coli; Genes, ras; Glycols; Guanine; Molecular Sequence Data; Mutagens; Oligonucleotides; Stereoisomerism; Templates, Genetic; Transfection

2000
Synthesis and characterization of nucleosides and oligonucleotides bearing adducts of butadiene epoxides on adenine n(6) and guanine n(2).
    Chemical research in toxicology, 2001, Volume: 14, Issue:4

    Topics: Adenine; Base Sequence; Circular Dichroism; Epoxy Compounds; Guanine; Mass Spectrometry; Nuclear Magnetic Resonance, Biomolecular; Nucleosides; Oligonucleotides

2001
Dose responses for DNA adduct formation in tissues of rats and mice exposed by inhalation to low concentrations of 1,3-[2,3-[(14)C]-butadiene.
    Chemico-biological interactions, 2004, Mar-15, Volume: 147, Issue:2

    Topics: Administration, Inhalation; Animals; Butadienes; Carbon Radioisotopes; Carcinogens, Environmental; Chromatography, High Pressure Liquid; DNA Adducts; DNA Damage; Dose-Response Relationship, Drug; Epoxy Compounds; Guanine; Liver; Lung; Male; Mice; Mice, Inbred Strains; Rats; Rats, Sprague-Dawley; Scintillation Counting; Species Specificity; Testis

2004
DNA adducts in rats and mice following exposure to [4-14C]-1,2-epoxy-3-butene and to [2,3-14C]-1,3-butadiene.
    Chemico-biological interactions, 2004, Jun-30, Volume: 148, Issue:1-2

    Topics: Animals; Butadienes; Carbon Radioisotopes; Carcinogens; Chromatography, High Pressure Liquid; DNA Adducts; Dose-Response Relationship, Drug; Epoxy Compounds; Guanine; Injections, Intraperitoneal; Liver; Lung; Male; Mice; Mice, Inbred Strains; Rats; Rats, Sprague-Dawley

2004