3,4-dimethyl-2,5-hexanedione has been researched along with 2,5-hexanedione in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (76.92) | 18.7374 |
| 1990's | 3 (23.08) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sabri, MI | 1 |
| Amarnath, V; Anthony, DC; Graham, DG; St Clair, MB | 1 |
| Autilio-Gambetti, L; Gambetti, P; Monaco, S; Patton, A; Sayre, LM; Schaetzle, B; Shearson, CM; Wongmongkolrit, T | 1 |
| Autilio-Gambetti, L; Gambetti, P; Sayre, LM | 1 |
| Sickles, DW | 1 |
| Anthony, DC; Graham, DG; St Clair, MB; Wikstrand, CJ | 1 |
| Anderson, CW; Anthony, DC; Genter, MB; Graham, DG; Szakál-Quin, G | 1 |
| Boekelheide, K | 2 |
| Anthony, DC; Boekelheide, K; Gottfried, MR; Graham, DG; Szakál-Quin, G | 1 |
| Anthony, DC; Graham, DG; Priest, JW; Szakál-Quin, G | 1 |
| Anderson, CW; Anthony, DC; Boekelheide, K; Graham, DG | 1 |
| Anthony, DC; Boekelheide, K; Graham, DG | 1 |
2 review(s) available for 3,4-dimethyl-2,5-hexanedione and 2,5-hexanedione
| Article | Year |
|---|---|
Molecular mechanisms of gamma-diketone neuropathy.
Topics: Animals; Axons; Biotransformation; Hexanes; Hexanones; Humans; Methyl n-Butyl Ketone; Peripheral Nervous System Diseases; Structure-Activity Relationship | 1991 |
Pathogenesis of experimental giant neurofilamentous axonopathies: a unified hypothesis based on chemical modification of neurofilaments.
Topics: Animals; Axonal Transport; Axons; Chickens; Cytoskeleton; Disease Models, Animal; Glyceraldehyde-3-Phosphate Dehydrogenases; Hexanones; Humans; In Vitro Techniques; Intermediate Filament Proteins; Intermediate Filaments; Mice; Nervous System Diseases; Neurofilament Proteins; Nitriles; Phosphorylation; Pyrroles; Rats | 1985 |
11 other study(ies) available for 3,4-dimethyl-2,5-hexanedione and 2,5-hexanedione
| Article | Year |
|---|---|
Effect of 2,5-hexanedione and 3,4-dimethyl-2,5-hexanedione on retrograde axonal transport in sciatic nerve.
Topics: Animals; Axons; Biological Transport; Hexanones; Iodine Radioisotopes; Male; Mice; Rats; Rats, Sprague-Dawley; Sciatic Nerve | 1992 |
Giant axonopathy characterized by intermediate location of axonal enlargements and acceleration of neurofilament transport.
Topics: Actins; Animals; Axons; Cytoskeleton; Hexanones; Intermediate Filament Proteins; Intermediate Filaments; Ketones; Macromolecular Substances; Male; Microscopy, Electron; Molecular Weight; Neurofilament Proteins; Neurotoxins; Optic Nerve; Rats; Rats, Inbred Strains; Reference Values; Sciatic Nerve; Tubulin; Visual Pathways | 1990 |
Toxic neurofilamentous axonopathies and fast anterograde axonal transport. II. The effects of single doses of neurotoxic and non-neurotoxic diketones and beta, beta'-iminodipropionitrile (IDPN) on the rate and capacity of transport.
Topics: Animals; Axonal Transport; Axons; Cytoskeleton; Hexanones; Intermediate Filaments; Male; Nerve Tissue Proteins; Nitriles; Peripheral Nervous System Diseases; Rats; Rats, Inbred Strains | 1989 |
Neurofilament protein crosslinking in gamma-diketone neuropathy: in vitro and in vivo studies using the seaworm myxicola infundibulum.
Topics: Alkylation; Animals; Axons; Cross-Linking Reagents; Cytoskeleton; Hexanones; Immunohistochemistry; Intermediate Filaments; Ketones; Nerve Tissue Proteins; Nervous System Diseases; Polychaeta | 1989 |
Evidence that pyrrole formation is a pathogenetic step in gamma-diketone neuropathy.
Topics: Animals; Hexanones; Intermediate Filaments; Isomerism; Ketones; Kinetics; Microscopy, Electron; Nervous System; Pepsin A; Rats | 1987 |
2,5-Hexanedione alters microtubule assembly. I. Testicular atrophy, not nervous system toxicity, correlates with enhanced tubulin polymerization.
Topics: Animals; Atrophy; Brain; Hexanones; Ketones; Male; Microtubules; Polymers; Rats; Testis; Tubulin | 1987 |
2,5-Hexanedione alters microtubule assembly. II. Enhanced polymerization of crosslinked tubulin.
Topics: Animals; Brain; Cattle; Dose-Response Relationship, Drug; Guanosine Triphosphate; Hexanones; Ketones; Kinetics; Microtubules; Polymers; Rats; Temperature; Tubulin | 1987 |
Covalent crosslinking of neurofilaments in the pathogenesis of n-hexane neuropathy.
Topics: Acrylamide; Acrylamides; Animals; Axons; Carbon Disulfide; Chemical Phenomena; Chemistry; Hexanones; Intermediate Filament Proteins; Intermediate Filaments; Ketones; Nervous System Diseases; Neurofilament Proteins; Nitriles; Rats | 1985 |
In vitro evidence that covalent crosslinking of neurofilaments occurs in gamma-diketone neuropathy.
Topics: Animals; Cross-Linking Reagents; Culture Techniques; Cytoskeleton; Hexanones; Ketones; Molecular Weight; Neurons; Rats | 1984 |
The effect of 3,4-dimethyl substitution on the neurotoxicity of 2,5-hexanedione. II. Dimethyl substitution accelerates pyrrole formation and protein crosslinking.
Topics: Animals; Brain; Chemical Phenomena; Chemistry; Electrophoresis, Polyacrylamide Gel; Erythrocyte Membrane; Hexanones; Ketones; Proteins; Pyrroles; Rats; Rats, Inbred Strains; Spectrophotometry, Ultraviolet | 1983 |
The effect of 3,4-dimethyl substitution on the neurotoxicity of 2,5-hexanedione. I. Accelerated clinical neuropathy is accompanied by more proximal axonal swellings.
Topics: Animals; Anterior Horn Cells; Axons; Body Weight; Brain; Cytoskeleton; Dose-Response Relationship, Drug; Hexanones; Ketones; Male; Organ Size; Rats; Rats, Inbred Strains; Testis | 1983 |