Page last updated: 2024-08-26

3,4-dihydroxypyridine and deferiprone

3,4-dihydroxypyridine has been researched along with deferiprone in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (33.33)18.2507
2000's3 (50.00)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
el-Jammal, A; Howell, PL; Li, N; Templeton, DM; Turner, MA1
Dobbin, PS; Hall, AD; Hider, RC; Porter, JB; Sarpong, P; Taylor, PD; van der Helm, D; Xiao, G1
Hider, RC; Khodr, HH; Liu, ZD; Lu, SL1
Chaves, S; Gano, L; Gil, M; Santos, MA1
Balzarini, J; Barral, K; Camplo, M; De Clercq, E; Hider, RC; Neyts, J1
Bansal, S; Hider, R; Kong, XL; Lu, Z; Xie, YY; Zhou, T1

Other Studies

6 other study(ies) available for 3,4-dihydroxypyridine and deferiprone

ArticleYear
Copper complexation by 3-hydroxypyridin-4-one iron chelators: structural and iron competition studies.
    Journal of medicinal chemistry, 1994, Feb-18, Volume: 37, Issue:4

    Topics: Antithyroid Agents; Copper; Deferiprone; Iron Chelating Agents; Ligands; Potentiometry; Pyridones; Spectrophotometry

1994
Synthesis, physicochemical properties, and biological evaluation of N-substituted 2-alkyl-3-hydroxy-4(1H)-pyridinones: orally active iron chelators with clinical potential.
    Journal of medicinal chemistry, 1993, Aug-20, Volume: 36, Issue:17

    Topics: Administration, Oral; Animals; Crystallography; Deferoxamine; Horses; Humans; Iron; Iron Chelating Agents; Liver; Mice; Pyridones; Rats; Stereoisomerism; Structure-Activity Relationship

1993
Design, synthesis and evaluation of N-basic substituted 3-hydroxypyridin-4-ones: orally active iron chelators with lysosomotrophic potential.
    The Journal of pharmacy and pharmacology, 2000, Volume: 52, Issue:3

    Topics: Alkalies; Animals; Biological Transport; Chemical Phenomena; Chemistry, Physical; Deferiprone; Dose-Response Relationship, Drug; Drug Design; Drug Evaluation; Ferritins; Hydrogen-Ion Concentration; Iron Chelating Agents; Iron Radioisotopes; Ligands; Liver; Lysosomes; Male; Pyridones; Rats; Rats, Wistar

2000
Bifunctional 3-hydroxy-4-pyridinone derivatives as potential pharmaceuticals: synthesis, complexation with Fe(III), Al(III) and Ga(III) and in vivo evaluation with 67Ga.
    Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 2005, Volume: 10, Issue:5

    Topics: Aluminum; Animals; Deferiprone; Drug Design; Gallium; Gallium Radioisotopes; Iron; Mice; Molecular Structure; Pyridones; Tissue Distribution

2005
Synthesis and antiviral evaluation of cyclic and acyclic 2-methyl-3-hydroxy-4-pyridinone nucleoside derivatives.
    Journal of medicinal chemistry, 2006, Jan-12, Volume: 49, Issue:1

    Topics: Animals; Antiviral Agents; Cell Line; Cell Proliferation; Chlorocebus aethiops; Deferiprone; HeLa Cells; Herpesvirus 1, Human; Herpesvirus 2, Human; HIV-1; HIV-2; Humans; Ligands; Microbial Sensitivity Tests; Molecular Structure; Nucleosides; Pyridones; Structure-Activity Relationship; Vero Cells

2006
Systematic comparison of the mono-, dimethyl- and trimethyl 3-hydroxy-4(1H)-pyridones - Attempted optimization of the orally active iron chelator, deferiprone.
    European journal of medicinal chemistry, 2016, Jun-10, Volume: 115

    Topics: Administration, Oral; Deferiprone; Humans; Hydrogen-Ion Concentration; Iron Chelating Agents; Microsomes, Liver; Pyridones

2016