3,4-dihydroxyphenylglycol and 6-methyl-2-(phenylethynyl)pyridine

Topics: Animals; Animals, Newborn; Brain; Cell Line; Cyclic AMP; Excitatory Amino Acid Antagonists; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Lithium Chloride; Male; Methoxyhydroxyphenylglycol; Oocytes; Phosphatidylinositols; Pyridines; Quisqualic Acid; Radioligand Assay; Rats; Rats, Inbred Strains; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Recombinant Proteins; Sulfur Radioisotopes; Transfection; Xenopus laevis

Topics: Animals; Behavior, Animal; Cold Temperature; Constriction, Pathologic; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Injections, Spinal; Male; Methoxyhydroxyphenylglycol; Pain; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Sciatic Nerve; Spinal Cord

Topics: Action Potentials; Amygdala; Animals; Arthritis; Chromones; Dose-Response Relationship, Drug; Glycine; Kaolin; Male; Methoxyhydroxyphenylglycol; Neurons; Phenylacetates; Physical Stimulation; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate

Topics: Animals; Aspartic Acid; Benzoates; Colforsin; Cyclic AMP; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Glycine; Hippocampus; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Male; Methoxyhydroxyphenylglycol; Pyridines; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate

Topics: Amino Acids, Dicarboxylic; Ammonia; Animals; Azetidinecarboxylic Acid; Cells, Cultured; Cerebellum; Excitatory Amino Acid Agonists; Immunoprecipitation; Methoxyhydroxyphenylglycol; Microtubule-Associated Proteins; Neurons; Phosphorylation; Pyridines; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate

Topics: Analysis of Variance; Animals; Animals, Newborn; Dicarboxylic Acids; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamates; In Vitro Techniques; Membrane Potentials; Methoxyhydroxyphenylglycol; Motor Neurons; Neural Inhibition; Patch-Clamp Techniques; Pyridines; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Spinal Cord; Synaptic Transmission

Topics: Analgesics, Opioid; Animals; Calcium; Coculture Techniques; Drug Tolerance; Excitatory Amino Acid Antagonists; Intracellular Membranes; Male; Methoxyhydroxyphenylglycol; Mice; Mice, Inbred ICR; Morphine; Neuroglia; Neurons; Nociceptors; Osmolar Concentration; Pyridines; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Spinal Cord

Topics: Animals; Animals, Newborn; Blotting, Western; Cells, Cultured; Cerebral Cortex; Cricetinae; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Fluorescent Antibody Technique; Gene Expression Regulation, Enzymologic; Glial Fibrillary Acidic Protein; Glucose; Hydrogen Peroxide; Hypoxia; Isoquinolines; Methoxyhydroxyphenylglycol; Mice; Neuroglia; Neurons; Piperidines; Poly(ADP-ribose) Polymerases; Pyridines; Receptors, Metabotropic Glutamate; Thiophenes; Time Factors; Transfection

Topics: Amyloid beta-Peptides; Animals; Benzoates; Cells, Cultured; Chromones; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hippocampus; In Vitro Techniques; Indoles; Methoxyhydroxyphenylglycol; Mice; Mice, Inbred C57BL; Microtubule-Associated Proteins; Morpholines; Neurons; Oncogene Protein v-akt; Peptide Fragments; Phosphorylation; Pyridines; Rats; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Serine; Signal Transduction

Topics: Animals; Benzopyrans; Blotting, Western; Electrophoresis, Polyacrylamide Gel; Immunohistochemistry; Male; Methoxyhydroxyphenylglycol; Neostriatum; Phosphorylation; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Serine

Topics: Amyotrophic Lateral Sclerosis; Animals; Animals, Genetically Modified; Aspartic Acid; Astrocytes; Blotting, Northern; Calcium; Carbachol; Cholinergic Agonists; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 2; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Glutamic Acid; Humans; Immunohistochemistry; Male; Methoxyhydroxyphenylglycol; Protein Kinase C; Pyridines; Rats; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium; Superoxide Dismutase; Tritium

Topics: Action Potentials; Amino Acids; Animals; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Extracellular Signal-Regulated MAP Kinases; Hippocampus; Long-Term Synaptic Depression; Methoxyhydroxyphenylglycol; Mice; Mice, Knockout; Neuronal Plasticity; Neurons; Neurotransmitter Agents; Phosphorylation; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, AMPA; Receptors, Metabotropic Glutamate; Synapses; Xanthenes

Topics: Anesthetics, Dissociative; Anesthetics, Intravenous; Animals; Chromones; Dose-Response Relationship, Drug; Glycine; Ketamine; Male; Methoxyhydroxyphenylglycol; Mice; Phenylacetates; Propofol; Pyridines; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Reflex

Topics: Animals; Animals, Newborn; Avoidance Learning; Behavior, Animal; Blotting, Western; Dose-Response Relationship, Radiation; Electric Stimulation; Enzyme Activation; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Excitatory Postsynaptic Potentials; Gene Expression; Glycine; Hippocampus; In Vitro Techniques; Long-Term Synaptic Depression; Methoxyhydroxyphenylglycol; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-kappa B; Patch-Clamp Techniques; Phenylacetates; Protein Binding; Protein Subunits; Proto-Oncogene Proteins c-rel; Pyridines; Receptors, Metabotropic Glutamate; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Synaptic Transmission; Time Factors

Topics: Animals; Animals, Newborn; Anisomycin; Benzoates; Blotting, Western; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Fluorescent Antibody Technique; Fragile X Mental Retardation Protein; Glycine; In Vitro Techniques; Leupeptins; Long-Term Synaptic Depression; Male; Methoxyhydroxyphenylglycol; Mice; Mice, Knockout; Microtubule-Associated Proteins; Models, Biological; Proteasome Endopeptidase Complex; Protein Biosynthesis; Protein Synthesis Inhibitors; Pyridines; Receptors, Metabotropic Glutamate; RNA, Messenger; Signal Transduction

Topics: Animals; Chromatography, High Pressure Liquid; Chromones; Dopamine; Drug Interactions; Electrochemistry; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Fluid; Male; Methoxyhydroxyphenylglycol; Microdialysis; Prefrontal Cortex; Pyridines; Rats; Receptors, Metabotropic Glutamate; Ventral Tegmental Area

Topics: Animals; Animals, Newborn; Astrocytes; Cell Count; Cell Proliferation; Cells, Cultured; Cerebral Cortex; Cycloleucine; Cyclopropanes; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycerophospholipids; Glycine; Indoles; Maleimides; Methoxyhydroxyphenylglycol; Phospholipase D; Pyridines; Rats; Rats, Wistar; Receptors, Glutamate; Tritium

Topics: Analysis of Variance; Animals; Area Under Curve; Behavior, Animal; Chromones; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Hyperalgesia; Male; Masseter Muscle; Methoxyhydroxyphenylglycol; Pain Threshold; Physical Stimulation; Protein Kinase C; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate

Topics: Animals; Benzoates; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; Hippocampus; Interneurons; Long-Term Potentiation; Methoxyhydroxyphenylglycol; Mice; Mice, Knockout; Patch-Clamp Techniques; Pyridines; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Synapses

Topics: Animals; Cells, Cultured; Embryo, Mammalian; Enzyme Activation; Excitatory Amino Acid Agents; Fragile X Mental Retardation Protein; Hippocampus; Immunoprecipitation; Methoxyhydroxyphenylglycol; Mutation; Neurons; Phosphorylation; Protein Phosphatase 2; Pyridines; Rats; Receptors, Metabotropic Glutamate; Signal Transduction; Time Factors; Transfection

Topics: Animals; Animals, Newborn; Arachidonic Acids; Benzoxazines; Cannabinoid Receptor Modulators; Drug Interactions; Endocannabinoids; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glycerides; Hippocampus; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Methoxyhydroxyphenylglycol; Morpholines; Naphthalenes; Neurons; Patch-Clamp Techniques; Piperidines; Pyrazoles; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Rimonabant; Synapses; Synapsins

Topics: Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Male; Methoxyhydroxyphenylglycol; Organ Culture Techniques; Patch-Clamp Techniques; Prefrontal Cortex; Pyramidal Cells; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Synapses; Synaptic Transmission

Topics: Animals; Cells, Cultured; Cerebral Cortex; CREB-Binding Protein; Cytoskeletal Proteins; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Extracellular Signal-Regulated MAP Kinases; Methoxyhydroxyphenylglycol; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Neurons; Proto-Oncogene Proteins c-fos; Pyridines; Receptors, Metabotropic Glutamate; RNA, Messenger; Signal Transduction; Time Factors; Up-Regulation

Topics: Allosteric Regulation; Animals; Calcium; Cognition; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Hippocampus; Injections, Intraperitoneal; Male; Methoxyhydroxyphenylglycol; Neurons; Oxadiazoles; Phosphorylation; Piperidines; Pyridines; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; src-Family Kinases

Topics: Amygdala; Analysis of Variance; Animals; Butadienes; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Formaldehyde; Functional Laterality; Gene Expression Regulation; Green Fluorescent Proteins; Hyperalgesia; Methoxyhydroxyphenylglycol; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinase 3; Nitriles; Pain; Pain Measurement; Pyridines; Receptors, Glucocorticoid; Receptors, Kainic Acid

Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Benzopyrans; Cells, Cultured; Dendritic Spines; Disease Models, Animal; Fragile X Mental Retardation Protein; Fragile X Syndrome; Hippocampus; Methoxyhydroxyphenylglycol; Mice; Mice, Inbred C57BL; Mice, Knockout; Neural Inhibition; Neurons; Pyridines; Receptors, Metabotropic Glutamate; Signal Transduction; Silver Staining

Topics: Animals; Blotting, Western; Convulsants; Dendrites; Dose-Response Relationship, Drug; Excitatory Amino Acid Transporter 3; Extracellular Signal-Regulated MAP Kinases; Fluorescent Antibody Technique; Hippocampus; Male; Methoxyhydroxyphenylglycol; Neurons; Pilocarpine; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; RNA, Messenger; Status Epilepticus; Synaptosomes; TOR Serine-Threonine Kinases

Topics: Action Potentials; Analysis of Variance; Animals; Animals, Newborn; Aspartic Acid; Astrocytes; Bacterial Proteins; Benzoates; Benzoxazines; Calcium; Calcium Channel Blockers; Carbenoxolone; Channelrhodopsins; Electric Stimulation; Excitatory Amino Acid Antagonists; Female; Glial Fibrillary Acidic Protein; Glycine; Green Fluorescent Proteins; Hippocampus; In Vitro Techniques; Luminescent Proteins; Male; Methoxyhydroxyphenylglycol; Mice; Mice, Inbred C57BL; Models, Biological; Morpholines; Naphthalenes; Neurons; Patch-Clamp Techniques; Peptide Fragments; Phosphopyruvate Hydratase; Photic Stimulation; Piperidines; Pyrazoles; Pyridines; Sodium Channel Blockers; Statistics, Nonparametric; Tetanus Toxin; Tetrodotoxin; Transduction, Genetic

Topics: Animals; CA1 Region, Hippocampal; CA3 Region, Hippocampal; Dendritic Spines; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Helplessness, Learned; Hydrolysis; Long-Term Synaptic Depression; Male; Methoxyhydroxyphenylglycol; Phosphatidylinositol Phosphates; Pyramidal Cells; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Synapses

Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aminobutyrates; Animals; Aspartic Acid; Chromones; Cyclopropanes; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Glycine; Male; Membrane Potentials; Methoxyhydroxyphenylglycol; Neurons; Periaqueductal Gray; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate

Topics: Analgesia; Analysis of Variance; Animals; Arachidonic Acids; Cannabinoid Receptor Modulators; Cyclohexanones; Dose-Response Relationship, Drug; Electroconvulsive Therapy; Endocannabinoids; Excitatory Amino Acid Antagonists; Glycerides; Lipoprotein Lipase; Male; Methoxyhydroxyphenylglycol; Mice; Microscopy, Immunoelectron; Pain; Periaqueductal Gray; Piperidines; Protease Inhibitors; Pyrazoles; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Rimonabant; RNA, Messenger; RNA, Small Interfering; Synapses; Tandem Mass Spectrometry

Topics: Action Potentials; Animals; Benzoates; Dopamine Antagonists; Drug Interactions; Excitatory Amino Acid Antagonists; Globus Pallidus; Glycine; Haloperidol; Male; Methoxyhydroxyphenylglycol; Movement; Neurons; Pyridines; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate

Topics: Animals; Blotting, Western; Cocaine-Related Disorders; Conditioning, Operant; Cues; Excitatory Amino Acid Antagonists; Extinction, Psychological; Injections; Male; Methoxyhydroxyphenylglycol; Prefrontal Cortex; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Recurrence; Self Administration; Substance Withdrawal Syndrome

Topics: Angelman Syndrome; Animals; Carrier Proteins; Disease Models, Animal; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Hemizygote; Hippocampus; Homer Scaffolding Proteins; Immunosuppressive Agents; In Vitro Techniques; Long-Term Synaptic Depression; Methoxyhydroxyphenylglycol; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mitogen-Activated Protein Kinase Kinases; Pyridines; Receptor, Metabotropic Glutamate 5; Signal Transduction; Sirolimus; Ubiquitin-Protein Ligases

Topics: Animals; Cell Differentiation; Cerebral Cortex; Disease Models, Animal; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Fragile X Syndrome; Humans; Male; Methoxyhydroxyphenylglycol; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Neural Stem Cells; Pyridines; Receptor, Metabotropic Glutamate 5

Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anhedonia; Animals; Glycine; Male; Mesencephalon; Methoxyhydroxyphenylglycol; Mice; Prefrontal Cortex; Pyridines; Receptors, AMPA; Receptors, Metabotropic Glutamate; Resorcinols; Social Dominance; Stress, Psychological

Topics: Aged; Fatigue; Genome-Wide Association Study; Humans; Jurkat Cells; Machine Learning; Male; Methoxyhydroxyphenylglycol; Middle Aged; NF-kappa B; Prostatic Neoplasms; Pyridines; Radiotherapy; Radiotherapy Dosage; Receptor, Metabotropic Glutamate 5; T-Lymphocytes; Transcriptome