Page last updated: 2024-08-25

3,4-dihydroxyphenylethanol and oleuropein

3,4-dihydroxyphenylethanol has been researched along with oleuropein in 114 studies

Research

Studies (114)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (2.63)18.2507
2000's27 (23.68)29.6817
2010's57 (50.00)24.3611
2020's27 (23.68)2.80

Authors

AuthorsStudies
Deguin, B; Halabalaki, M; Lemus, C; Michel, S; Pergola, C; Skaltsounis, L; Smith, AB; Vougogiannopoulou, K; Werz, O1
Aligiannis, N; Argyropoulou, A; Christoforidou, N; Gaboriaud-Kolar, N; Ioannou, K; Lemus, C; Paronis, E; Samara, P; Skaltsounis, AL; Tsitsilonis, O; Vougogiannopoulou, K1
Blasevich, M; Galli, C; Montedoro, GF; Papini, N; Petroni, A; Salami, M1
de la Puerta, R; Hoult, JR; Ruiz Gutierrez, V1
Bisignano, G; Crisafi, G; Lo Cascio, R; Saija, A; Tomaino, A; Uccella, N1
Catalá, A; de la Puerta, R; Gutierrez, VR1
de la Puerta, R; Flavill, JA; Hoult, JR; Martínez Domínguez, ME; Ruíz-Gutíerrez, V1
Briante, R; Febbraio, F; La Cara, F; Nucci, R; Patumi, M1
Katan, MB; Leenen, R; Roodenburg, AJ; Vissers, MN; Zock, PL1
Hayball, PJ; Kirlich, A; Stupans, I; Tuck, KL1
Fregapane, G; Gómez-Alonso, S; Salvador, MD1
Celli, N; De Curtis, A; Del Boccio, P; Di Deo, A; Iacoviello, L; Rotilio, D1
Hayball, PJ; Stupans, I; Tan, HW; Tuck, KL1
Ancora, MA; Carluccio, MA; De Caterina, R; Distante, A; Massaro, M; Scoditti, E; Siculella, L; Storelli, C; Visioli, F1
Covas, MI; de la Torre, R; Farre, M; Fito, M; Miro-Casas, E; Ortuño, J; Roset, P; Weinbrenner, T1
Caruso, D; Colonnelli, K; Galli, C; Galli, G; Grande, S; Patelli, C; Visioli, F1
d'Ischia, M; Giudicianni, I; Napolitano, A; Panzella, L; Paolillo, L; Sacchi, R; Savarese, M1
Gordon, MH; Paiva-Martins, F1
Alonso, MG; de Pascual-Teresa, S; Etienne, N; Minihane, AM; Rimbach, G; Turner, R; Weinberg, PD1
Agalias, A; Aligiannis, N; Bazios, D; Doulias, PT; Galaris, D; Mitakou, S; Nousis, L1
Bosisio, E; Caruso, D; Crestani, M; De Fabiani, E; Dell'Agli, M; Fagnani, R; Galli, GV; Masciadri, M; Mitro, N; Mussoni, L; Scurati, S; Tremoli, E1
Corsetti, A; Esposto, S; Massitti, O; Montedoro, GF; Servili, M; Settanni, L; Taticchi, A; Urbani, S; Veneziani, G1
Bao, J; Chang, YT; Huang, PL; Lee, JW; Lee-Huang, S; Sun, Y; Zhang, D; Zhang, J2
Bernini, R; Gambacorta, A; Migliorini, A; Tofani, D1
Bao, J; Huang, PL; Lee-Huang, S; Zhang, DW; Zhang, JZ1
Brenes, M; de Castro, A; García, A; Medina, E; Romero, C1
Bouaziz, M; El Feki, A; Fki, I; Jemai, H; Sayadi, S1
Papoti, VT; Tsimidou, MZ1
Fregapane, G; Gómez-Rico, A; Inarejos-García, AM; Salvador, MD1
Amado, F; Belo, L; Borges, F; Fernandes, J; Nascimento, H; Paiva-Martins, F; Rocha, S; Santos-Silva, A; Vitorino, R1
El Feki, A; Jemai, H; Sayadi, S1
Gikas, E; Magiatis, P; Melliou, E; Skaltsounis, AL; Tsarbopoulos, A; Zoidou, E1
Andò, S; Casaburi, I; Chimento, A; De Luca, A; Iacopetta, D; Maggiolini, M; Onofrio, A; Pezzi, V; Puoci, F; Rizza, P; Sirianni, R1
Ortega-García, F; Peragón, J1
Calheiros, R; Marques, MP; Paiva-Martins, F; Rodrigues, V1
Araki, M; Goto, T; Hagiwara, H; Hagiwara, K; Miyazaki, H1
Chen, S; Drira, R; Sakamoto, K1
Andújar, I; Cerdá-Nicolás, JM; Giner, E; Giner, RM; Recio, MC; Ríos, JL1
Charoenprasert, S; Mitchell, A1
Castro, PM; Kalogerakis, N; Piccirillo, C; Pintado, ME; Santos, MM1
Giannakoula, A; Koundouras, S; Petridis, A; Samouris, G; Therios, I1
Constantinou, AI; Odiatou, EM; Skaltsounis, AL1
Alarcón de la Lastra, C; Cárdeno, A; Rosillo, MA; Sánchez-Hidalgo, M1
Cutfield, WS; de Bock, M; Derraik, JG; Henderson, HV; Hofman, PL; Thorstensen, EB1
Avena, P; Campana, C; Casaburi, I; Chimento, A; De Luca, A; Maggiolini, M; Martire, E; Pezzi, V; Rosano, C; Santolla, MF; Sirianni, R1
Gnoni, GV; Priore, P; Siculella, L1
Catalán, Ú; Farràs, M; Macià, A; Martín-Peláez, S; Mosele, JI; Motilva, MJ; Valls, RM1
Fogal, TH; Mariani, ML; Penissi, AB; Persia, FA1
Bulotta, S; Celano, M; Lepore, SM; Montalcini, T; Pujia, A; Russo, D1
Bali, EB; Bayraktar, O; Ergin, V; Karasu, Ç; Küçükboyaci, N; Rackova, L1
Tao, R; Wang, CZ; Ye, JZ; Yuan, JJ; Zhang, YS1
Castañeda-Saucedo, MC; de la Serrana, HL; Ramírez-Anaya, Jdel P; Samaniego-Sánchez, C; Villalón-Mir, M1
Golan-Goldhirsh, A; Gopas, J; Osheroff, N; Sedgeman, CA; Vann, KR1
Koike, T; Matsuo, T; Murotomi, K; Nakajima, Y; Takashima, M; Umeno, A; Yoshida, Y1
Bouallagui, Z; Hadrich, F; Isoda, H; Junkyu, H; Sayadi, S1
Gikas, E; Lemonakis, N; Skaltsounis, AL; Tsarbopoulos, A1
Jazayeri, JA; John, G; Lim, A; Obied, HK; Subhan, N; Vanniasinkam, T1
Brenes, M; García, P; Medina, E; Ramírez, E; Romero, C1
Amiot, MJ; Coxam, V; Georgé, S; Goncalves, A; Lebecque, P; Margier, M; Reboul, E; Tagliaferri, C; Wittrant, Y1
Kopjar, N; Kosalec, I; Kraljić, K; Oršolić, N; Tomić, S; Zorić, N1
Cicerale, S; Parkinson, L1
Morales, FJ; Navarro, M; Ramos, S1
Bauduin, P; Diat, O; Fadel, O; Girard, L; Gomes Rodrigues, D; L'Hermitte, A; Le Goff, X; Rossignol-Castera, A1
Hauser, C; Kohnen, S; Thielmann, J1
Frost, B; Liu, J; Sun, W1
Finamore, A; Monteleone, JI; Palmeri, R; Restuccia, C; Serafini, M; Siracusa, L; Spagna, G; Sperlinga, E1
Bedouhene, S; Dang, PM; El-Benna, J; Moulti-Mati, F1
Fuentes, E; Jimenez, P; Ortiz, J; Paucar, F; Romero, N; Tapia, F1
Bonacci, S; Cariati, L; Costanzo, P; Nardi, M; Oliverio, M; Procopio, A1
Chen, A; Feng, Q; Wu, L; Xu, C; Xu, Y1
Liu, M; Yong, Q; Yu, S1
Aponte, M; Blaiotta, G; Calignano, A; d'Angelo, I; Dal Piaz, F; De Caro, C; Miro, A; Russo, R; Ungaro, F1
Ayadi, L; Bouallagui, Z; Feki, I; Ghorbel, H; Guermazi, F; Mahmoudi, A; Sayadi, S1
Argiriou, A; Makris, A; Mougiou, N; Trantas, E; Trikka, F; Ververidis, F; Vlachonasios, KE1
Bouallagui, Z; Feki, I; Fourati, H; Ghorbel, H; Hadrich, F; Mahmoudi, A; Marrekchi, R; Sayadi, S1
Amir, RM; Gilani, SA; Imran, M; Khan, S; Nadeem, M; Sajid, MW1
Bonofiglio, M; Bonofiglio, R; Giordano, F; La Russa, A; Lofaro, D; Lupinacci, S; Parisi, OI; Perri, A; Puoci, F; Toteda, G; Vizza, D1
Alkhatib, A; Tsang, C; Tuomilehto, J1
Bond, DR; Goldsmith, CD; Jankowski, H; Roach, PD; Scarlett, CJ; Stathopoulos, CE; Weidenhofer, J1
Aree, T; Jongrungruangchok, S1
Ali Ahmed, S; Boumendjel, M; Houali, K; Lahcene, S; Mestar, N; Ouafi, S; Taibi, F1
Leal-Hernandez, O; Moran, JM; Pedrera-Zamorano, JD; Roncero-Martin, R1
Cabrera-Bañegil, M; Delgado-Adámez, J; Fernández, A; Lodolini, EM; Martín-Vertedor, D; Ramírez, R1
Chehab, H; Hammami, M; Mechri, B; Tekaya, M1
Huang, C; Lian, Z; Liu, M; Yong, Q; Yu, S1
Ding, T; Huan, F; Jiang, S; Long, YF; Lu, HY; Shen, WJ; Wang, SL; Wu, B; Zhang, Z; Zhu, JS1
Guodong, R; Jianguo, Z; Xiaoxia, L; Ying, L1
Tian, M; Wen, M; Zhang, L; Zhang, Y; Zhou, J; Zhou, P1
Daoued, I; Fki, I; Ghorbel, H; Mahmoudi, A; Marrekchi, R; Sayadi, S1
Ding, T; Jiang, S; Lu, HY; Shen, WJ; Wang, SL; Wu, B; Xie, J; Zhang, Z; Zhu, J; Zhu, JS1
Chaari, A1
Buiatti, S; Guglielmotti, M; Passaghe, P1
Kopjar, N; Kosalec, I; Rodriguez, JV; Tomić, S; Zorić, N1
Breakspear, I; Guillaume, C1
Kalogiouri, NP; Kolyvira, L; Kritikou, E; Thomaidis, NS1
Bonacci, S; Costanzo, P; Di Gioia, ML; Mancuso, S; Nardi, M; Oliverio, M; Procopio, A1
Augello, G; Azzolina, A; Cervello, M; Cusimano, A; Di Stefano, V; Emma, MR; Giannitrapani, L; Montalto, G1
Carrera-González, MP; Martínez-Martos, JM; Mayas, MD; Ramírez-Expósito, MJ1
Díez-Pascual, AM; Sainz-Urruela, C; San Andrés, MP; Vera-López, S1
Hioki, T; Iida, H; Kim, W; Kozawa, O; Kuroyanagi, G; Matsushima-Nishiwaki, R; Tachi, J; Tokuda, H1
Akanji, T; Gutkowski, J; He, H; Li, D; Li, H; Li, R; Liu, C; Ma, H; Seeram, NP; Wan, Y; Wu, P1
Chung, JS; Kwon, SM; Lee, DH; Ly, TTG; Yun, J1
Ishimaru, K; Kotoda, N; Matsuo, Y; Nakayama, H; Nishi, N; Tanaka, T1
Caggia, C; Cattivelli, A; Martini, S; Pino, A; Randazzo, CL; Solieri, L; Tagliazucchi, D; Vaccalluzzo, A1
Angelis, A; Antoniadi, L; Chountoulesi, M; Demetzos, C; Halabalaki, M; Lei, J; Li, W; Mitakou, S; Skaltsounis, LA; Wang, C1
Chatzikonstantinou, AV; Chochos, CL; Giannakopoulou, A; Houhoula, D; Stamatis, H; Tsakni, A1
Di Mattia, CD; Gonzalez-Ortega, R; Natasa, PU; Pittia, P1
Brocchini, S; Nardi, M; Procopio, A; Somavarapu, S1
Accardi, G; Aiello, A; Allegra, M; Calabrò, A; Candore, G; Caruso, C; Gervasi, F; Ligotti, ME; Pojero, F; Procopio, A1
Bissoli, I; Borzì, RM; Cetrullo, S; D'Adamo, S; Flamigni, F; Panichi, V1
Bernini, R; Bertini, L; Bonato, A; Caruso, C; Caruso, M; Micheli, L; Tirone, F; Villanova, N1
Ayadi, L; Bouallagui, Z; Chamkha, M; Feki, I; Ghorbel, H; Hadrich, F; Mahmoudi, A; Sayadi, S1
Accardi, G; Aiello, A; Allegra, M; Attanzio, A; Bonacci, S; Caldarella, R; Candore, G; Caruso, C; Fiore, SD; Gervasi, F; Ligotti, ME; Pojero, F; Procopio, A; Restivo, I; Tesoriere, L1

Reviews

13 review(s) available for 3,4-dihydroxyphenylethanol and oleuropein

ArticleYear
Factors influencing phenolic compounds in table olives (Olea europaea).
    Journal of agricultural and food chemistry, 2012, Jul-25, Volume: 60, Issue:29

    Topics: Antioxidants; Diet, Mediterranean; Drug Stability; Flavonoids; Food Handling; Fruit; Health Promotion; Hot Temperature; Humans; Iridoid Glucosides; Iridoids; Olea; Phenol; Phenylethyl Alcohol; Pyrans; Seeds; Species Specificity

2012
Beneficial effects of the olive oil phenolic components oleuropein and hydroxytyrosol: focus on protection against cardiovascular and metabolic diseases.
    Journal of translational medicine, 2014, Aug-03, Volume: 12

    Topics: Animals; Cardiovascular Diseases; Diabetes Mellitus; Humans; Iridoid Glucosides; Iridoids; Metabolic Diseases; Olive Oil; Phenylethyl Alcohol; Plant Oils

2014
The Health Benefiting Mechanisms of Virgin Olive Oil Phenolic Compounds.
    Molecules (Basel, Switzerland), 2016, Dec-16, Volume: 21, Issue:12

    Topics: Aldehydes; Animals; Anti-Inflammatory Agents; Biological Availability; Cyclopentane Monoterpenes; Dietary Supplements; Humans; Iridoid Glucosides; Iridoids; Olive Oil; Phenols; Phenylethyl Alcohol

2016
Antimicrobial activity of Olea europaea Linné extracts and their applicability as natural food preservative agents.
    International journal of food microbiology, 2017, Jun-19, Volume: 251

    Topics: Aldehydes; Anti-Infective Agents; Food Preservatives; Fruit; Iridoid Glucosides; Iridoids; Olea; Phenols; Phenylethyl Alcohol; Plant Extracts; Plant Leaves; Pyrans

2017
Antitumor Perspectives of Oleuropein and Its Metabolite Hydroxytyrosol: Recent Updates.
    Journal of food science, 2018, Volume: 83, Issue:7

    Topics: Animals; Antineoplastic Agents; Cell Movement; Cell Proliferation; Coronary Disease; DNA Damage; Humans; Iridoid Glucosides; Iridoids; Neoplasm Invasiveness; Neoplasms; Neovascularization, Pathologic; Olea; Olive Oil; Phenylethyl Alcohol; Pyrans

2018
Olive Oil Nutraceuticals in the Prevention and Management of Diabetes: From Molecules to Lifestyle.
    International journal of molecular sciences, 2018, Jul-12, Volume: 19, Issue:7

    Topics: Diabetes Mellitus, Type 2; Dietary Fats; Dietary Supplements; Humans; Iridoid Glucosides; Iridoids; Life Style; Olive Oil; Phenylethyl Alcohol

2018
Semi-synthesis as a tool for broadening the health applications of bioactive olive secoiridoids: a critical review.
    Natural product reports, 2021, 03-01, Volume: 38, Issue:3

    Topics: Aldehydes; Cyclopentane Monoterpenes; Iridoid Glucosides; Iridoids; Olea; Olive Oil; Phenols; Phenylethyl Alcohol

2021
Potential Uses of Olive Oil Secoiridoids for the Prevention and Treatment of Cancer: A Narrative Review of Preclinical Studies.
    International journal of molecular sciences, 2021, Jan-27, Volume: 22, Issue:3

    Topics: Aldehydes; Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Antioxidants; Cyclopentane Monoterpenes; Diet, Mediterranean; Glucosides; Humans; Iridoid Glucosides; Iridoids; Neoplasms; Olive Oil; Phenols; Phenylethyl Alcohol; Pyrans

2021
Graphene-Based Sensors for the Detection of Bioactive Compounds: A Review.
    International journal of molecular sciences, 2021, Mar-24, Volume: 22, Issue:7

    Topics: Antioxidants; Ascorbic Acid; Biosensing Techniques; Curcumin; Electric Conductivity; Electrodes; Free Radicals; Gallic Acid; Graphite; Humans; Iridoid Glucosides; Melatonin; Metals; Nanocomposites; Nanostructures; Oxides; Phenylethyl Alcohol; Quantum Dots; Resveratrol; Tannins; Tocopherols

2021
Protective Effects and Benefits of Olive Oil and Its Extracts on Women's Health.
    Nutrients, 2021, Nov-27, Volume: 13, Issue:12

    Topics: Animals; Diet, Healthy; Diet, Mediterranean; Female; Humans; Iridoid Glucosides; Olea; Olive Oil; Phenylethyl Alcohol; Plant Oils; Polyphenols; Protective Agents; Women's Health

2021
Hydroxytyrosol oleate: A promising neuroprotective nanocarrier delivery system of oleuropein and derivatives.
    International journal of pharmaceutics, 2023, Jan-25, Volume: 631

    Topics: Antioxidants; Humans; Male; Neuroblastoma; Olea; Oleic Acid; Olive Oil; Phenols; Phenylethyl Alcohol; Plant Oils

2023
Effects of Oleuropein and Hydroxytyrosol on Inflammatory Mediators: Consequences on Inflammaging.
    International journal of molecular sciences, 2022, Dec-26, Volume: 24, Issue:1

    Topics: Antioxidants; Humans; Inflammation; Inflammation Mediators; Iridoid Glucosides; Iridoids; Olive Oil; Phenylethyl Alcohol

2022
Role of Hydroxytyrosol and Oleuropein in the Prevention of Aging and Related Disorders: Focus on Neurodegeneration, Skeletal Muscle Dysfunction and Gut Microbiota.
    Nutrients, 2023, Apr-04, Volume: 15, Issue:7

    Topics: Gastrointestinal Microbiome; Muscle, Skeletal; Olive Oil

2023

Trials

1 trial(s) available for 3,4-dihydroxyphenylethanol and oleuropein

ArticleYear
Human absorption and metabolism of oleuropein and hydroxytyrosol ingested as olive (Olea europaea L.) leaf extract.
    Molecular nutrition & food research, 2013, Volume: 57, Issue:11

    Topics: Absorption; Adult; Antioxidants; Chromatography, Liquid; Dose-Response Relationship, Drug; Female; Humans; Iridoid Glucosides; Iridoids; Male; Middle Aged; Olea; Phenylethyl Alcohol; Plant Extracts; Plant Leaves; Polyphenols; Pyrans; Tandem Mass Spectrometry

2013

Other Studies

100 other study(ies) available for 3,4-dihydroxyphenylethanol and oleuropein

ArticleYear
One-step semisynthesis of oleacein and the determination as a 5-lipoxygenase inhibitor.
    Journal of natural products, 2014, Mar-28, Volume: 77, Issue:3

    Topics: Aldehydes; Anti-Inflammatory Agents; Arachidonate 5-Lipoxygenase; Cyclopentane Monoterpenes; Glucosides; Humans; Iridoid Glucosides; Iridoids; Lipoxygenase Inhibitors; Molecular Structure; Olea; Phenols; Plant Extracts; Plant Leaves; Pyrans

2014
New semi-synthetic analogs of oleuropein show improved anticancer activity in vitro and in vivo.
    European journal of medicinal chemistry, 2017, Sep-08, Volume: 137

    Topics: Animals; Antineoplastic Agents; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Iridoid Glucosides; Iridoids; Male; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Molecular Structure; Structure-Activity Relationship; Tumor Cells, Cultured

2017
Inhibition of platelet aggregation and eicosanoid production by phenolic components of olive oil.
    Thrombosis research, 1995, Apr-15, Volume: 78, Issue:2

    Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Adenosine Diphosphate; Antioxidants; Collagen; Eicosanoids; Flavonoids; Humans; Hydroxyeicosatetraenoic Acids; Iridoid Glucosides; Iridoids; Olive Oil; Phenylethyl Alcohol; Plant Extracts; Plant Oils; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyrans; Thromboxane B2

1995
Inhibition of leukocyte 5-lipoxygenase by phenolics from virgin olive oil.
    Biochemical pharmacology, 1999, Feb-15, Volume: 57, Issue:4

    Topics: Animals; Antioxidants; Caffeic Acids; Dietary Fats, Unsaturated; Eicosanoids; Iridoid Glucosides; Iridoids; Leukocytes; Lipoxygenase Inhibitors; Male; Olive Oil; Phenylethyl Alcohol; Plant Oils; Pyrans; Rats; Rats, Wistar; Reactive Oxygen Species

1999
On the in-vitro antimicrobial activity of oleuropein and hydroxytyrosol.
    The Journal of pharmacy and pharmacology, 1999, Volume: 51, Issue:8

    Topics: Anti-Bacterial Agents; Bacteria; Dose-Response Relationship, Drug; In Vitro Techniques; Iridoid Glucosides; Iridoids; Microbial Sensitivity Tests; Phenylethyl Alcohol; Pyrans

1999
The effect of tyrosol, hydroxytyrosol and oleuropein on the non-enzymatic lipid peroxidation of rat liver microsomes.
    Molecular and cellular biochemistry, 2001, Volume: 217, Issue:1-2

    Topics: Animals; Cholesterol; Fatty Acids; Iridoid Glucosides; Iridoids; Lipid Peroxidation; Microsomes, Liver; Oxidation-Reduction; Phenylethyl Alcohol; Phospholipids; Pyrans; Rats; Rats, Wistar

2001
Effects of virgin olive oil phenolics on scavenging of reactive nitrogen species and upon nitrergic neurotransmission.
    Life sciences, 2001, Jul-27, Volume: 69, Issue:10

    Topics: Animals; Antioxidants; Caffeic Acids; Dose-Response Relationship, Drug; Free Radical Scavengers; Iridoid Glucosides; Iridoids; Male; Muscle Relaxation; Muscle, Smooth; Neural Conduction; Nitrates; Nitric Oxide; Nitroprusside; Olive Oil; Phenols; Phenylethyl Alcohol; Plant Oils; Pyrans; Rats; Rats, Wistar

2001
Bioactive derivatives from oleuropein by a biotransformation on Olea europaea leaf extracts.
    Journal of biotechnology, 2002, Feb-14, Volume: 93, Issue:2

    Topics: Antioxidants; Bioreactors; Biotransformation; Chromatography, Gas; Chromatography, High Pressure Liquid; Colorimetry; Iridoid Glucosides; Iridoids; Lipid Peroxidation; Oleaceae; Phenylethyl Alcohol; Plant Extracts; Plant Leaves; Pyrans

2002
Olive oil phenols are absorbed in humans.
    The Journal of nutrition, 2002, Volume: 132, Issue:3

    Topics: Absorption; Adult; Colon; Dietary Supplements; Drug Stability; Female; Humans; Ileostomy; Iridoid Glucosides; Iridoids; Male; Olive Oil; Phenols; Phenylethyl Alcohol; Placebos; Plant Oils; Pyrans

2002
Comparison of radical scavenging effect, inhibition of microsomal oxygen free radical generation, and serum lipoprotein oxidation of several natural antioxidants.
    Journal of agricultural and food chemistry, 2002, Apr-10, Volume: 50, Issue:8

    Topics: Animals; Antioxidants; Aryl Hydrocarbon Hydroxylases; Bepridil; Biphenyl Compounds; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Free Radical Scavengers; Gallic Acid; Humans; Iridoid Glucosides; Iridoids; Lipid Peroxidation; Lipoproteins, LDL; Male; Microsomes, Liver; Olive Oil; Oxidoreductases, N-Demethylating; Phenylethyl Alcohol; Picrates; Plant Oils; Pyrans; Rats; Rats, Wistar; Reactive Oxygen Species; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases

2002
Phenolic compounds profile of cornicabra virgin olive oil.
    Journal of agricultural and food chemistry, 2002, Nov-06, Volume: 50, Issue:23

    Topics: Chromatography, High Pressure Liquid; Colorimetry; Drug Stability; Flavonoids; Iridoid Glucosides; Iridoids; Olive Oil; Oxidation-Reduction; Phenols; Phenylethyl Alcohol; Plant Oils; Polymers; Polyphenols; Pyrans; Seasons

2002
Liquid chromatography-tandem mass spectrometry analysis of oleuropein and its metabolite hydroxytyrosol in rat plasma and urine after oral administration.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2003, Feb-25, Volume: 785, Issue:1

    Topics: Administration, Oral; Animals; Calibration; Iridoid Glucosides; Iridoids; Phenylethyl Alcohol; Pyrans; Rats; Sensitivity and Specificity

2003
Simultaneous determination of oleuropein and hydroxytyrosol in rat plasma using liquid chromatography with fluorescence detection.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2003, Feb-25, Volume: 785, Issue:1

    Topics: Animals; Calibration; Chromatography, High Pressure Liquid; Iridoid Glucosides; Iridoids; Phenylethyl Alcohol; Pyrans; Rats; Sensitivity and Specificity; Spectrometry, Fluorescence

2003
Olive oil and red wine antioxidant polyphenols inhibit endothelial activation: antiatherogenic properties of Mediterranean diet phytochemicals.
    Arteriosclerosis, thrombosis, and vascular biology, 2003, Apr-01, Volume: 23, Issue:4

    Topics: Animals; Antioxidants; Arteriosclerosis; Cattle; Cell Adhesion; Cells, Cultured; Diet; Endothelium, Vascular; Flavonoids; Gene Expression Regulation; Humans; Iridoid Glucosides; Iridoids; NF-kappa B; Olive Oil; Phenols; Phenylethyl Alcohol; Plant Oils; Polyphenols; Pyrans; Resveratrol; RNA, Messenger; Stilbenes; Transcription Factor AP-1; Transcription, Genetic; U937 Cells; Vascular Cell Adhesion Molecule-1; Wine

2003
Hydroxytyrosol disposition in humans.
    Clinical chemistry, 2003, Volume: 49, Issue:6 Pt 1

    Topics: Adult; Antioxidants; Female; Gas Chromatography-Mass Spectrometry; Humans; Iridoid Glucosides; Iridoids; Male; Middle Aged; Olive Oil; Phenylethyl Alcohol; Plant Oils; Pyrans

2003
Hydroxytyrosol excretion differs between rats and humans and depends on the vehicle of administration.
    The Journal of nutrition, 2003, Volume: 133, Issue:8

    Topics: Animals; Antioxidants; Drug Combinations; Humans; Hydrolysis; Iridoid Glucosides; Iridoids; Olive Oil; Pharmaceutical Vehicles; Phenylethyl Alcohol; Plant Oils; Pyrans; Rats; Species Specificity; Yogurt

2003
Acid-induced structural modifications of unsaturated Fatty acids and phenolic olive oil constituents by nitrite ions: a chemical assessment.
    Chemical research in toxicology, 2004, Volume: 17, Issue:10

    Topics: Acids; Alkenes; Antineoplastic Agents; Fatty Acids, Unsaturated; Gas Chromatography-Mass Spectrometry; Hydrogen-Ion Concentration; Ions; Iridoid Glucosides; Iridoids; Isomerism; Magnetic Resonance Spectroscopy; Nitrites; Nitrosation; Olive Oil; Phenols; Phenylethyl Alcohol; Plant Oils; Pyrans

2004
Interactions of ferric ions with olive oil phenolic compounds.
    Journal of agricultural and food chemistry, 2005, Apr-06, Volume: 53, Issue:7

    Topics: Drug Stability; Ferric Compounds; Hydrogen-Ion Concentration; Iridoid Glucosides; Iridoids; Olive Oil; Phenols; Phenylethyl Alcohol; Plant Oils; Pyrans

2005
Antioxidant and anti-atherogenic activities of olive oil phenolics.
    International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 2005, Volume: 75, Issue:1

    Topics: Antioxidants; Arteriosclerosis; Cell Adhesion Molecules; Cells, Cultured; Chemokine CCL2; Endothelium; Homovanillic Acid; Hydrogen Peroxide; In Vitro Techniques; Intercellular Adhesion Molecule-1; Iridoid Glucosides; Iridoids; Lipoproteins, LDL; Macrophages; Nitric Oxide; Olive Oil; Phenols; Phenylethyl Alcohol; Plant Oils; Platelet Aggregation; Pyrans; Vascular Cell Adhesion Molecule-1

2005
DNA protecting and genotoxic effects of olive oil related components in cells exposed to hydrogen peroxide.
    Free radical research, 2005, Volume: 39, Issue:7

    Topics: Caffeic Acids; Chromatography, High Pressure Liquid; Comet Assay; DNA; DNA Damage; Humans; Hydrogen Peroxide; Iridoid Glucosides; Iridoids; Jurkat Cells; Nuclear Magnetic Resonance, Biomolecular; Olea; Olive Oil; Phenylethyl Alcohol; Plant Extracts; Plant Oils; Pyrans

2005
Minor components of olive oil modulate proatherogenic adhesion molecules involved in endothelial activation.
    Journal of agricultural and food chemistry, 2006, May-03, Volume: 54, Issue:9

    Topics: Cell Adhesion Molecules; E-Selectin; Endothelium, Vascular; Gene Expression; Humans; Intercellular Adhesion Molecule-1; Iridoid Glucosides; Iridoids; Olive Oil; Phenylethyl Alcohol; Plant Oils; Pyrans; RNA, Messenger; Umbilical Veins; Vascular Cell Adhesion Molecule-1

2006
The use of Lactobacillus pentosus 1MO to shorten the debittering process time of black table olives (Cv. Itrana and Leccino): a pilot-scale application.
    Journal of agricultural and food chemistry, 2006, May-31, Volume: 54, Issue:11

    Topics: Fermentation; Food Handling; Fruit; Hydrogen-Ion Concentration; Iridoid Glucosides; Iridoids; Lactobacillus; Olea; Phenols; Phenylethyl Alcohol; Pyrans; Taste

2006
Discovery of small-molecule HIV-1 fusion and integrase inhibitors oleuropein and hydroxytyrosol: part II. integrase inhibition.
    Biochemical and biophysical research communications, 2007, Mar-23, Volume: 354, Issue:4

    Topics: Catalytic Domain; HIV Integrase; HIV Integrase Inhibitors; Iridoid Glucosides; Iridoids; Models, Molecular; Phenylethyl Alcohol; Pyrans; Structure-Activity Relationship

2007
Discovery of small-molecule HIV-1 fusion and integrase inhibitors oleuropein and hydroxytyrosol: Part I. fusion [corrected] inhibition.
    Biochemical and biophysical research communications, 2007, Mar-23, Volume: 354, Issue:4

    Topics: Chromatography, Liquid; Circular Dichroism; Electrophoresis, Polyacrylamide Gel; HIV Envelope Protein gp41; HIV Integrase Inhibitors; HIV-1; Iridoid Glucosides; Iridoids; Mass Spectrometry; Models, Molecular; Phenylethyl Alcohol; Pyrans

2007
High-yielding preparation of a stable precursor of hydroxytyrosol by total synthesis and from the natural glycoside oleuropein.
    Journal of agricultural and food chemistry, 2007, May-02, Volume: 55, Issue:9

    Topics: Antioxidants; Drug Stability; Food Additives; Iridoid Glucosides; Iridoids; Phenylethyl Alcohol; Pyrans

2007
Computational study of bindings of olive leaf extract (OLE) to HIV-1 fusion protein gp41.
    FEBS letters, 2007, Jun-12, Volume: 581, Issue:14

    Topics: Antiviral Agents; Computer Simulation; HIV Envelope Protein gp41; HIV-1; Humans; Hydrogen Bonding; Iridoid Glucosides; Iridoids; Models, Molecular; Molecular Structure; Olea; Phenylethyl Alcohol; Plant Extracts; Plant Leaves; Protein Binding; Pyrans; Thermodynamics

2007
Main antimicrobial compounds in table olives.
    Journal of agricultural and food chemistry, 2007, Nov-28, Volume: 55, Issue:24

    Topics: Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Fermentation; Iridoid Glucosides; Iridoids; Lactobacillus; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Olea; Phenylethyl Alcohol; Pyrans; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet

2007
Hypolipidimic and antioxidant activities of oleuropein and its hydrolysis derivative-rich extracts from Chemlali olive leaves.
    Chemico-biological interactions, 2008, Nov-25, Volume: 176, Issue:2-3

    Topics: Animals; Antioxidants; beta-Glucosidase; Catalase; Cholesterol, Dietary; Enzyme Activation; Heart; Hydrochloric Acid; Hydrolysis; Hypercholesterolemia; Iridoid Glucosides; Iridoids; Lipid Peroxidation; Lipids; Liver; Male; Molecular Structure; Olea; Organ Size; Phenylethyl Alcohol; Plant Extracts; Plant Leaves; Pyrans; Rats; Rats, Wistar; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances

2008
Impact of sampling parameters on the radical scavenging potential of olive (Olea europaea L.) leaves.
    Journal of agricultural and food chemistry, 2009, May-13, Volume: 57, Issue:9

    Topics: Flavonoids; Free Radical Scavengers; Iridoid Glucosides; Iridoids; Olea; Phenols; Phenylethyl Alcohol; Plant Extracts; Plant Leaves; Pyrans; Species Specificity; Time Factors

2009
Effect of malaxation conditions on phenol and volatile profiles in olive paste and the corresponding virgin olive oils (Olea europaea L. Cv. Cornicabra).
    Journal of agricultural and food chemistry, 2009, May-13, Volume: 57, Issue:9

    Topics: Aldehydes; Consumer Behavior; Food Handling; Fruit; Iridoid Glucosides; Iridoids; Olea; Olive Oil; Phenols; Phenylethyl Alcohol; Plant Oils; Pyrans; Temperature; Volatilization

2009
Effects of olive oil polyphenols on erythrocyte oxidative damage.
    Molecular nutrition & food research, 2009, Volume: 53, Issue:5

    Topics: Adult; Amino Acid Sequence; Erythrocytes; Female; Flavonoids; Humans; Iridoid Glucosides; Iridoids; Male; Membrane Proteins; Middle Aged; Molecular Sequence Data; Olive Oil; Phenols; Phenylethyl Alcohol; Plant Oils; Polyphenols; Pyrans

2009
Antidiabetic and antioxidant effects of hydroxytyrosol and oleuropein from olive leaves in alloxan-diabetic rats.
    Journal of agricultural and food chemistry, 2009, Oct-14, Volume: 57, Issue:19

    Topics: Animals; Antioxidants; Blood Glucose; Diabetes Mellitus, Experimental; Hypoglycemic Agents; Iridoid Glucosides; Iridoids; Liver; Male; Olea; Oxidative Stress; Phenylethyl Alcohol; Phytotherapy; Plant Extracts; Plant Leaves; Pyrans; Rats; Rats, Wistar

2009
Identification of Throuba Thassos, a traditional Greek table olive variety, as a nutritional rich source of oleuropein.
    Journal of agricultural and food chemistry, 2010, Jan-13, Volume: 58, Issue:1

    Topics: Food Handling; Greece; Humans; Iridoid Glucosides; Iridoids; Nutritive Value; Olea; Phenylethyl Alcohol; Pyrans

2010
Oleuropein and hydroxytyrosol inhibit MCF-7 breast cancer cell proliferation interfering with ERK1/2 activation.
    Molecular nutrition & food research, 2010, Volume: 54, Issue:6

    Topics: Anticarcinogenic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Enzyme Activation; Estradiol; Estrogen Receptor alpha; Female; Humans; Iridoid Glucosides; Iridoids; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phenylethyl Alcohol; Protein Kinase Inhibitors; Pyrans; Transcriptional Activation

2010
HPLC analysis of oleuropein, hydroxytyrosol, and tyrosol in stems and roots of Olea europaea L. cv. Picual during ripening.
    Journal of the science of food and agriculture, 2010, Volume: 90, Issue:13

    Topics: Antioxidants; Chromatography, High Pressure Liquid; Fruit; Iridoid Glucosides; Iridoids; Olea; Phenylethyl Alcohol; Plant Leaves; Plant Roots; Plant Stems; Pyrans; Seasons; Spain; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2010
Characterization of antioxidant olive oil biophenols by spectroscopic methods.
    Journal of the science of food and agriculture, 2011, Jan-30, Volume: 91, Issue:2

    Topics: Antioxidants; Iridoid Glucosides; Iridoids; Olea; Olive Oil; Phenols; Phenylethyl Alcohol; Plant Oils; Pyrans; Spectrum Analysis, Raman

2011
Olive polyphenol hydroxytyrosol prevents bone loss.
    European journal of pharmacology, 2011, Jul-15, Volume: 662, Issue:1-3

    Topics: 3T3 Cells; Animals; Female; Flavonoids; Humans; Iridoid Glucosides; Iridoids; Male; Mice; Olea; Osteoblasts; Osteoclasts; Osteogenesis; Osteoporosis; Ovariectomy; Phenols; Phenylethyl Alcohol; Polyphenols; Pyrans

2011
Oleuropein and hydroxytyrosol inhibit adipocyte differentiation in 3 T3-L1 cells.
    Life sciences, 2011, Nov-07, Volume: 89, Issue:19-20

    Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Animals; Antioxidants; Cell Differentiation; Cell Survival; Dose-Response Relationship, Drug; Down-Regulation; Flow Cytometry; Iridoid Glucosides; Iridoids; Mice; Mitosis; Phenylethyl Alcohol; Pyrans; Reverse Transcriptase Polymerase Chain Reaction; Triglycerides

2011
Oleuropein ameliorates acute colitis in mice.
    Journal of agricultural and food chemistry, 2011, Dec-28, Volume: 59, Issue:24

    Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Colitis; Cytokines; Dextran Sulfate; Female; Iridoid Glucosides; Iridoids; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; Nitric Oxide; Phenylethyl Alcohol; Pyrans

2011
Bioconversion of oleuropein to hydroxytyrosol by lactic acid bacteria.
    World journal of microbiology & biotechnology, 2012, Volume: 28, Issue:6

    Topics: Iridoid Glucosides; Iridoids; Lactobacillus; Olea; Phenylethyl Alcohol; Pyrans

2012
Effect of water deficit on leaf phenolic composition, gas exchange, oxidative damage and antioxidant activity of four Greek olive (Olea europaea L.) cultivars.
    Plant physiology and biochemistry : PPB, 2012, Volume: 60

    Topics: Agricultural Irrigation; Antioxidants; Chlorophyll; Chlorophyll A; Dehydration; Genotype; Iridoid Glucosides; Iridoids; Lipid Peroxidation; Malondialdehyde; Olea; Oxidative Stress; Phenols; Phenylethyl Alcohol; Photosynthesis; Plant Leaves; Plant Roots; Plant Transpiration; Pyrans; Stress, Physiological

2012
Identification of the factors responsible for the in vitro pro-oxidant and cytotoxic activities of the olive polyphenols oleuropein and hydroxytyrosol.
    Cancer letters, 2013, Mar-01, Volume: 330, Issue:1

    Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Culture Media; Female; Humans; Hydrogen Peroxide; Iridoid Glucosides; Iridoids; Mice; Olea; Oxidants; Oxidative Stress; Phenylethyl Alcohol; Plant Extracts; Plant Oils; Pyrans; Reactive Oxygen Species

2013
Oleuropein, a secoiridoid derived from olive tree, inhibits the proliferation of human colorectal cancer cell through downregulation of HIF-1α.
    Nutrition and cancer, 2013, Volume: 65, Issue:1

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Cycle; Cell Proliferation; Colorectal Neoplasms; Down-Regulation; HT29 Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; I-kappa B Proteins; Iridoid Glucosides; Iridoids; NF-kappa B; NF-KappaB Inhibitor alpha; Olea; p38 Mitogen-Activated Protein Kinases; Phenylethyl Alcohol; PPAR gamma; Pyrans; Tumor Suppressor Protein p53

2013
Oleuropein and hydroxytyrosol activate GPER/ GPR30-dependent pathways leading to apoptosis of ER-negative SKBR3 breast cancer cells.
    Molecular nutrition & food research, 2014, Volume: 58, Issue:3

    Topics: Apoptosis; Breast Neoplasms; Cell Proliferation; Extracellular Signal-Regulated MAP Kinases; Female; Humans; Iridoid Glucosides; Iridoids; Phenylethyl Alcohol; Receptors, Estrogen; Receptors, G-Protein-Coupled; Signal Transduction; Tumor Cells, Cultured

2014
Extra virgin olive oil phenols down-regulate lipid synthesis in primary-cultured rat-hepatocytes.
    The Journal of nutritional biochemistry, 2014, Volume: 25, Issue:7

    Topics: Acetyl-CoA Carboxylase; AMP-Activated Protein Kinases; Animals; Cells, Cultured; Cholesterol; Diacylglycerol O-Acyltransferase; Down-Regulation; Fatty Acids; Hepatocytes; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Iridoid Glucosides; Iridoids; Lipids; Lipogenesis; Male; Olive Oil; Phenylethyl Alcohol; Phosphorylation; Plant Oils; Rats, Wistar

2014
Faecal microbial metabolism of olive oil phenolic compounds: in vitro and in vivo approaches.
    Molecular nutrition & food research, 2014, Volume: 58, Issue:9

    Topics: Acetates; Catechols; Colon; Feces; Fermentation; Humans; In Vitro Techniques; Iridoid Glucosides; Iridoids; Kinetics; Microbiota; Nontherapeutic Human Experimentation; Olive Oil; Phenols; Phenylethyl Alcohol; Plant Oils

2014
Hydroxytyrosol and oleuropein of olive oil inhibit mast cell degranulation induced by immune and non-immune pathways.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2014, Sep-25, Volume: 21, Issue:11

    Topics: Animals; beta-N-Acetylhexosaminidases; Cell Degranulation; Dose-Response Relationship, Drug; Iridoid Glucosides; Iridoids; Male; Mast Cells; Olive Oil; Phenylethyl Alcohol; Plant Oils; Rats, Wistar

2014
Olive leaf extracts protect cardiomyocytes against 4-hydroxynonenal-induced toxicity in vitro: comparison with oleuropein, hydroxytyrosol, and quercetin.
    Planta medica, 2014, Volume: 80, Issue:12

    Topics: Aldehydes; Animals; Antioxidants; Caspase 3; Cell Survival; In Vitro Techniques; Iridoid Glucosides; Iridoids; Mitochondria; Myocytes, Cardiac; Olea; Oxidative Stress; Phenylethyl Alcohol; Plant Extracts; Plant Leaves; Polyphenols; Protective Agents; Protein Serine-Threonine Kinases; Quercetin; Rats; Transcription Factors

2014
Enzymatic hydrolysis of oleuropein from Olea europea (olive) leaf extract and antioxidant activities.
    Molecules (Basel, Switzerland), 2015, Feb-11, Volume: 20, Issue:2

    Topics: Antioxidants; Biotransformation; Hydrolysis; Iridoid Glucosides; Iridoids; Olea; Phenylethyl Alcohol; Plant Extracts; Plant Leaves; Pyrans

2015
Phenols and the antioxidant capacity of Mediterranean vegetables prepared with extra virgin olive oil using different domestic cooking techniques.
    Food chemistry, 2015, Dec-01, Volume: 188

    Topics: Antioxidants; Benzothiazoles; Chlorogenic Acid; Chromatography, High Pressure Liquid; Cluster Analysis; Cooking; Cucurbita; Dietary Fats; Furans; Iridoid Glucosides; Iridoids; Lignans; Multivariate Analysis; Olive Oil; Phenols; Phenylethyl Alcohol; Rutin; Solanum lycopersicum; Solanum melongena; Solanum tuberosum; Sulfonic Acids; Vegetables

2015
Effects of Olive Metabolites on DNA Cleavage Mediated by Human Type II Topoisomerases.
    Biochemistry, 2015, Jul-28, Volume: 54, Issue:29

    Topics: DNA Cleavage; DNA Topoisomerases, Type II; Drug Screening Assays, Antitumor; Fruit; Glucosides; Humans; Iridoid Glucosides; Iridoids; Olea; Phenols; Phenylethyl Alcohol; Plant Bark; Plant Extracts; Plant Leaves; Plasmids; Topoisomerase II Inhibitors

2015
Radical-scavenging Activity and Antioxidative Effects of Olive Leaf Components Oleuropein and Hydroxytyrosol in Comparison with Homovanillic Alcohol.
    Journal of oleo science, 2015, Volume: 64, Issue:7

    Topics: Antioxidants; Chromans; Free Radical Scavengers; Homovanillic Acid; Iridoid Glucosides; Iridoids; Linoleic Acids; Lipid Peroxidation; Micelles; Olea; Oxidation-Reduction; Phenylethyl Alcohol; Plant Leaves

2015
The α-Glucosidase and α-Amylase Enzyme Inhibitory of Hydroxytyrosol and Oleuropein.
    Journal of oleo science, 2015, Volume: 64, Issue:8

    Topics: alpha-Amylases; alpha-Glucosidases; Caco-2 Cells; Cell Survival; Dose-Response Relationship, Drug; Glycoside Hydrolase Inhibitors; Humans; Hyperglycemia; Iridoid Glucosides; Iridoids; Olea; Phenylethyl Alcohol; Phytotherapy; Plant Leaves

2015
Optimization of parameters affecting signal intensity in an LTQ-orbitrap in negative ion mode: A design of experiments approach.
    Talanta, 2016, Jan-15, Volume: 147

    Topics: Iridoid Glucosides; Iridoids; Phenylethyl Alcohol; Spectrometry, Mass, Electrospray Ionization; Syringes

2016
Plant Phenols as Antibiotic Boosters: In Vitro Interaction of Olive Leaf Phenols with Ampicillin.
    Phytotherapy research : PTR, 2016, Volume: 30, Issue:3

    Topics: Ampicillin; Anti-Bacterial Agents; Bacteria; Caffeic Acids; Drug Synergism; Escherichia coli; Flavones; Glucosides; Herb-Drug Interactions; Iridoid Glucosides; Iridoids; Medicine, Traditional; Olea; Phenols; Phenylethyl Alcohol; Plant Extracts; Plant Leaves; Staphylococcus aureus

2016
Oleuropein hydrolysis in natural green olives: Importance of the endogenous enzymes.
    Food chemistry, 2016, Sep-01, Volume: 206

    Topics: beta-Glucosidase; Esterases; Food Handling; Food Storage; Hot Temperature; Hydrogen-Ion Concentration; Hydrolysis; Iridoid Glucosides; Iridoids; Olea; Phenols; Phenylethyl Alcohol; Pyrans; Salts; Taste

2016
Pinoresinol of olive oil decreases vitamin D intestinal absorption.
    Food chemistry, 2016, Sep-01, Volume: 206

    Topics: Animals; Caco-2 Cells; Docosahexaenoic Acids; Female; Furans; Humans; Intestinal Absorption; Iridoid Glucosides; Iridoids; Lignans; Olive Oil; Phenylethyl Alcohol; Polyphenols; Rats; Rats, Wistar; Vitamin D

2016
Olive leaf extract activity against Candida albicans and C. dubliniensis - the in vitro viability study.
    Acta pharmaceutica (Zagreb, Croatia), 2016, Sep-01, Volume: 66, Issue:3

    Topics: Anti-Bacterial Agents; Antifungal Agents; Antioxidants; Candida; Candida albicans; Cell Nucleus; Cell Nucleus Shape; Chromatography, High Pressure Liquid; Coloring Agents; Fluorescent Dyes; Iridoid Glucosides; Iridoids; Microbial Sensitivity Tests; Olea; Phenylethyl Alcohol; Plant Extracts; Plant Leaves; Trypan Blue

2016
Olive leaf extract concentrated in hydroxytyrosol attenuates protein carbonylation and the formation of advanced glycation end products in a hepatic cell line (HepG2).
    Food & function, 2017, Mar-22, Volume: 8, Issue:3

    Topics: Antioxidants; Glycation End Products, Advanced; Hep G2 Cells; Hepatocytes; Humans; Iridoid Glucosides; Iridoids; Olea; Phenylethyl Alcohol; Plant Extracts; Plant Leaves; Protein Carbonylation

2017
Micellization in vegetable oils: A structural characterisation.
    Colloids and surfaces. B, Biointerfaces, 2017, Jun-01, Volume: 154

    Topics: Antioxidants; Benzhydryl Compounds; Cosmetics; Emulsifying Agents; Flavones; Glucosides; Glycerol; Humans; Iridoid Glucosides; Iridoids; Micelles; Phenylethyl Alcohol; Plant Oils; Solubility; Stearic Acids; Waxes

2017
Oleuropein, unexpected benefits!
    Oncotarget, 2017, Mar-14, Volume: 8, Issue:11

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Blood Pressure; Diet, Mediterranean; Humans; Hypertension; Iridoid Glucosides; Iridoids; Mice; Olea; Oxidative Stress; Parkinson Disease; Phenylethyl Alcohol; Rats

2017
Bioactivity Improvement of Olea europaea Leaf Extract Biotransformed by Wickerhamomyces anomalus Enzymes.
    Plant foods for human nutrition (Dordrecht, Netherlands), 2017, Volume: 72, Issue:2

    Topics: beta-Glucosidase; Biotransformation; Caco-2 Cells; Coumaric Acids; Esterases; Humans; Hydrolysis; Iridoid Glucosides; Iridoids; Olea; Phenols; Phenylethyl Alcohol; Plant Leaves; Polyphenols; Saccharomycetales

2017
Oleuropein and hydroxytyrosol inhibit the N-formyl-methionyl-leucyl-phenylalanine-induced neutrophil degranulation and chemotaxis via AKT, p38, and ERK1/2 MAP-Kinase inhibition.
    Inflammopharmacology, 2017, Volume: 25, Issue:6

    Topics: Anti-Inflammatory Agents; Chemotaxis; Humans; Iridoid Glucosides; Iridoids; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phenylethyl Alcohol; Phosphorylation; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Signal Transduction

2017
Effect of the composition of extra virgin olive oils on the differentiation and antioxidant capacities of twelve monovarietals.
    Food chemistry, 2018, Mar-15, Volume: 243

    Topics: Agriculture; Antioxidants; Chile; Food Analysis; Furans; Glucosides; Iridoid Glucosides; Iridoids; Least-Squares Analysis; Lignans; Olive Oil; Phenylethyl Alcohol; Principal Component Analysis; Pyrans

2018
Simple and efficient sustainable semi-synthesis of oleacein [2-(3,4-hydroxyphenyl) ethyl (3S,4E)-4-formyl-3-(2-oxoethyl)hex-4-enoate] as potential additive for edible oils.
    Food chemistry, 2018, Apr-15, Volume: 245

    Topics: Aldehydes; Food Additives; Humans; Iridoid Glucosides; Iridoids; Phenols; Phenylethyl Alcohol; Plant Oils

2018
Protective Effects of Olive Leaf Extract on Acrolein-Exacerbated Myocardial Infarction via an Endoplasmic Reticulum Stress Pathway.
    International journal of molecular sciences, 2018, Feb-07, Volume: 19, Issue:2

    Topics: Acrolein; Animals; Apoptosis; Biological Products; Biomarkers; Cell Line; Cytoprotection; Disease Progression; Endoplasmic Reticulum Stress; Iridoid Glucosides; Iridoids; Isoproterenol; Male; Myocardial Infarction; Myocytes, Cardiac; Particulate Matter; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley

2018
Efficient bioconversion of oleuropein from olive leaf extract to antioxidant hydroxytyrosol by enzymatic hydrolysis and high-temperature degradation.
    Biotechnology and applied biochemistry, 2018, Volume: 65, Issue:5

    Topics: Antioxidants; Enzymes; Esters; Hot Temperature; Hydrolysis; Iridoid Glucosides; Iridoids; Olea; Phenylethyl Alcohol; Plant Extracts; Plant Leaves

2018
Improving in vivo conversion of oleuropein into hydroxytyrosol by oral granules containing probiotic Lactobacillus plantarum 299v and an Olea europaea standardized extract.
    International journal of pharmaceutics, 2018, May-30, Volume: 543, Issue:1-2

    Topics: Administration, Oral; Animals; Bile; Drug Carriers; Drug Liberation; Feces; Gastric Juice; Iridoid Glucosides; Iridoids; Lactobacillus plantarum; Male; Mice; Olea; Phenylethyl Alcohol; Plant Extracts; Plant Leaves; Probiotics

2018
Oleuropein and hydroxytyrosol protect rats' pups against bisphenol A induced hypothyroidism.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 103

    Topics: Animals; Animals, Suckling; Benzhydryl Compounds; Endocrine Disruptors; Female; Hypothyroidism; Iridoid Glucosides; Iridoids; Lactation; Olea; Phenols; Phenylethyl Alcohol; Plant Leaves; Protective Agents; Rats; Thyroid Hormones

2018
Expression of hydroxytyrosol and oleuropein biosynthetic genes are correlated with metabolite accumulation during fruit development in olive, Olea europaea, cv. Koroneiki.
    Plant physiology and biochemistry : PPB, 2018, Volume: 128

    Topics: Fruit; Gene Expression Regulation, Plant; Genes, Plant; Iridoid Glucosides; Iridoids; Olea; Phenylethyl Alcohol

2018
Oleuropein and hydroxytyrosol rich extracts from olive leaves attenuate liver injury and lipid metabolism disturbance in bisphenol A-treated rats.
    Food & function, 2018, Jun-20, Volume: 9, Issue:6

    Topics: Animals; Antioxidants; Benzhydryl Compounds; Humans; Iridoid Glucosides; Iridoids; Lipid Metabolism; Liver Diseases; Male; Olea; Phenols; Phenylethyl Alcohol; Plant Extracts; Plant Leaves; Rats

2018
Olive leaf extract counteracts epithelial to mesenchymal transition process induced by peritoneal dialysis, through the inhibition of TGFβ1 signaling.
    Cell biology and toxicology, 2019, Volume: 35, Issue:2

    Topics: Antigens, Differentiation; Cadherins; Cell Line; Cell Membrane; Epithelial-Mesenchymal Transition; Glucosides; Humans; Iridoid Glucosides; Iridoids; Olea; Peritoneal Dialysis; Phenols; Phenylethyl Alcohol; Plant Extracts; Signal Transduction; Smad Proteins, Receptor-Regulated; Transforming Growth Factor beta1

2019
The Olive Biophenols Oleuropein and Hydroxytyrosol Selectively Reduce Proliferation, Influence the Cell Cycle, and Induce Apoptosis in Pancreatic Cancer Cells.
    International journal of molecular sciences, 2018, Jul-02, Volume: 19, Issue:7

    Topics: Apoptosis; Apoptosis Regulatory Proteins; Cell Cycle; Cell Line, Tumor; Humans; Iridoid Glucosides; Iridoids; Neoplasm Proteins; Olea; Pancreatic Neoplasms; Phenylethyl Alcohol

2018
Structure-antioxidant activity relationship of β-cyclodextrin inclusion complexes with olive tyrosol, hydroxytyrosol and oleuropein: Deep insights from X-ray analysis, DFT calculation and DPPH assay.
    Carbohydrate polymers, 2018, Nov-01, Volume: 199

    Topics: beta-Cyclodextrins; Crystallography, X-Ray; Free Radical Scavengers; Hydrogen Bonding; Iridoid Glucosides; Iridoids; Models, Chemical; Molecular Structure; Phenylethyl Alcohol; Quantum Theory; Structure-Activity Relationship; Thermodynamics

2018
Insecticidal effects of the Olea europaea subsp. laperrinei extracts on the flour Pyralid Ephestia kuehniella.
    Cellular and molecular biology (Noisy-le-Grand, France), 2018, Aug-30, Volume: 64, Issue:11

    Topics: Animals; Chromatography, High Pressure Liquid; Female; Hesperidin; Insecticides; Iridoid Glucosides; Iridoids; Larva; Moths; Olea; Phenylethyl Alcohol; Plant Extracts; Plant Leaves; Quercetin

2018
Antitumor Perspectives of Oleuropein.
    Journal of food science, 2019, Volume: 84, Issue:3

    Topics: Iridoid Glucosides; Iridoids; Phenylethyl Alcohol

2019
Monitoring of acrylamide and phenolic compounds in table olive after high hydrostatic pressure and cooking treatments.
    Food chemistry, 2019, Jul-15, Volume: 286

    Topics: Acrylamide; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Cooking; Hydrostatic Pressure; Iridoid Glucosides; Iridoids; Olea; Olive Oil; Phenols; Phenylethyl Alcohol; Tandem Mass Spectrometry

2019
Root verbascoside and oleuropein are potential indicators of drought resistance in olive trees (Olea europaea L.).
    Plant physiology and biochemistry : PPB, 2019, Volume: 141

    Topics: Antioxidants; Apigenin; Droughts; Flavonoids; Glucosides; Iridoid Glucosides; Iridoids; Olea; Phenol; Phenols; Phenylethyl Alcohol; Plant Extracts; Plant Leaves; Plant Roots; Polyphenols; Spectrophotometry, Ultraviolet; Stress, Physiological; Water

2019
Continuous Bioconversion of Oleuropein from Olive Leaf Extract to Produce the Bioactive Product Hydroxytyrosol Using Carrier-Immobilized Enzyme.
    Applied biochemistry and biotechnology, 2020, Volume: 190, Issue:1

    Topics: Alginates; Biomass; Bioreactors; Cellulase; Ceramics; Chitosan; Enzymes, Immobilized; Hydrolysis; Iridoid Glucosides; Iridoids; Microscopy, Electron, Scanning; Olea; Phenylethyl Alcohol; Plant Leaves; Substrate Specificity; Thermogravimetry

2020
Hydroxytyrosol and Oleuropein Inhibit Migration and Invasion of MDA-MB-231 Triple-Negative Breast Cancer Cell via Induction of Autophagy.
    Anti-cancer agents in medicinal chemistry, 2019, Volume: 19, Issue:16

    Topics: Antineoplastic Agents; Autophagy; Autophagy-Related Proteins; Cell Line, Tumor; Cell Movement; Cell Survival; Gene Expression; Humans; Iridoid Glucosides; Iridoids; Neoplasm Invasiveness; Phenylethyl Alcohol; Triple Negative Breast Neoplasms

2019
Identification of putative genes for polyphenol biosynthesis in olive fruits and leaves using full-length transcriptome sequencing.
    Food chemistry, 2019, Dec-01, Volume: 300

    Topics: Alternative Splicing; Biosynthetic Pathways; Flavonoids; Fruit; Gene Expression Regulation, Plant; Iridoid Glucosides; Iridoids; Olea; Phenylethyl Alcohol; Plant Leaves; Polyphenols; Sequence Analysis, DNA; Transcriptome

2019
Analysis of chemical composition in Chinese olive leaf tea by UHPLC-DAD-Q-TOF-MS/MS and GC-MS and its lipid-lowering effects on the obese mice induced by high-fat diet.
    Food research international (Ottawa, Ont.), 2020, Volume: 128

    Topics: Animals; Beverages; Chromatography, Liquid; Diet, High-Fat; Gas Chromatography-Mass Spectrometry; Hyperlipidemias; Iridoid Glucosides; Iridoids; Male; Mice; Mice, Inbred ICR; Obesity; Olea; Phenylethyl Alcohol; Plant Leaves; Tandem Mass Spectrometry

2020
Comparative Study on Beneficial Effects of Hydroxytyrosol- and Oleuropein-Rich Olive Leaf Extracts on High-Fat Diet-Induced Lipid Metabolism Disturbance and Liver Injury in Rats.
    BioMed research international, 2020, Volume: 2020

    Topics: Animals; Dietary Fats; Iridoid Glucosides; Iridoids; Lipid Metabolism; Liver; Liver Diseases; Male; Olea; Phenylethyl Alcohol; Plant Extracts; Plant Leaves; Rats

2020
Hydroxytyrosol and Oleuropein Inhibit Migration and Invasion via Induction of Autophagy in ER-Positive Breast Cancer Cell Lines (MCF7 and T47D).
    Nutrition and cancer, 2021, Volume: 73, Issue:2

    Topics: Autophagy; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Female; Humans; Iridoid Glucosides; MCF-7 Cells; Phenylethyl Alcohol

2021
Inhibition of human islet amyloid polypeptide aggregation and cellular toxicity by oleuropein and derivatives from olive oil.
    International journal of biological macromolecules, 2020, Nov-01, Volume: 162

    Topics: Acetates; Cell Survival; Cyclopentane Monoterpenes; Diabetes Mellitus, Type 2; Diet, Mediterranean; Fluorescence; Humans; Inhibitory Concentration 50; Iridoid Glucosides; Iridoids; Islet Amyloid Polypeptide; Islets of Langerhans; Microscopy, Atomic Force; Olive Oil; Phenylethyl Alcohol; Phospholipids; Pyrans; Structure-Activity Relationship

2020
Use of olive (Olea europaea L.) leaves as beer ingredient, and their influence on beer chemical composition and antioxidant activity.
    Journal of food science, 2020, Volume: 85, Issue:8

    Topics: Antioxidants; Beer; Female; Food Handling; Humans; Humulus; Iridoid Glucosides; Iridoids; Male; Olea; Phenols; Phenylethyl Alcohol; Plant Extracts; Plant Leaves; Polyphenols; Taste

2020
Protective effects of olive oil phenolics oleuropein and hydroxytyrosol against hydrogen peroxide-induced DNA damage in human peripheral lymphocytes.
    Acta pharmaceutica (Zagreb, Croatia), 2021, Mar-01, Volume: 71, Issue:1

    Topics: Antioxidants; DNA Damage; Dose-Response Relationship, Drug; Free Radical Scavengers; Humans; Hydrogen Peroxide; Iridoid Glucosides; Iridoids; Lymphocytes; Olive Oil; Phenylethyl Alcohol

2021
A Quantitative Phytochemical Comparison of Olive Leaf Extracts on the Australian Market.
    Molecules (Basel, Switzerland), 2020, Sep-08, Volume: 25, Issue:18

    Topics: Antioxidants; Iridoid Glucosides; Iridoids; Olea; Phenylethyl Alcohol; Phytochemicals; Plant Extracts; Plant Leaves; Plants, Medicinal; Polyphenols

2020
Target and Suspect HRMS Metabolomics for the Determination of Functional Ingredients in 13 Varieties of Olive Leaves and Drupes from Greece.
    Molecules (Basel, Switzerland), 2020, Oct-22, Volume: 25, Issue:21

    Topics: Chromatography, High Pressure Liquid; Geography; Greece; Hot Temperature; Iridoid Glucosides; Iridoids; Limit of Detection; Metabolomics; Olea; Phenylethyl Alcohol; Plant Extracts; Plant Leaves; Reproducibility of Results; Seasons; Seeds; Tandem Mass Spectrometry; Time Factors

2020
Gender differences in the antioxidant response of oral administration of hydroxytyrosol and oleuropein against N-ethyl-N-nitrosourea (ENU)-induced glioma.
    Food research international (Ottawa, Ont.), 2021, Volume: 140

    Topics: Administration, Oral; Animals; Antioxidants; Ethylnitrosourea; Glioma; Iridoid Glucosides; Phenylethyl Alcohol; Rats; Sex Characteristics

2021
Olive polyphenols attenuate TNF-α-stimulated M-CSF and IL-6 synthesis in osteoblasts: Suppression of Akt and p44/p42 MAP kinase signaling pathways.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021, Volume: 141

    Topics: 3T3 Cells; Animals; Culture Media, Conditioned; Interleukin-6; Iridoid Glucosides; Macrophage Colony-Stimulating Factor; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinase 1; Olea; Oncogene Protein v-akt; Phenylethyl Alcohol; Polyphenols; Rotenone; Signal Transduction; Tumor Necrosis Factor-alpha

2021
Dietary polyphenol oleuropein and its metabolite hydroxytyrosol are moderate skin permeable elastase and collagenase inhibitors with synergistic cellular antioxidant effects in human skin fibroblasts.
    International journal of food sciences and nutrition, 2022, Volume: 73, Issue:4

    Topics: Antioxidants; Fibroblasts; Humans; Hydrogen Peroxide; Iridoid Glucosides; Iridoids; Matrix Metalloproteinase Inhibitors; Pancreatic Elastase; Phenylethyl Alcohol; Polyphenols; Reactive Oxygen Species

2022
A new secoiridoid glucoside from
    Journal of Asian natural products research, 2022, Volume: 24, Issue:11

    Topics: Esters; Glucosides; Iridoid Glucosides; Iridoids; Molecular Structure; Olea

2022
Metabolomic and Transcriptional Profiling of Oleuropein Bioconversion into Hydroxytyrosol during Table Olive Fermentation by
    Applied and environmental microbiology, 2022, 03-22, Volume: 88, Issue:6

    Topics: Fermentation; Iridoid Glucosides; Olea; Phenylethyl Alcohol

2022
Development and physicochemical characterization of nanoliposomes with incorporated oleocanthal, oleacein, oleuropein and hydroxytyrosol.
    Food chemistry, 2022, Aug-01, Volume: 384

    Topics: Aldehydes; Cyclopentane Monoterpenes; Humans; Iridoid Glucosides; Olea; Phenols; Phenylethyl Alcohol

2022
A Bi-enzymatic Immobilized Nanobiocatalyst for the Biotransformation of Oleuropein to Hydroxytyrosol.
    Methods in molecular biology (Clifton, N.J.), 2022, Volume: 2487

    Topics: Biotransformation; Candida; Enzymes, Immobilized; Iridoid Glucosides; Phenylethyl Alcohol

2022
Effect of heat treatment on phenolic composition and radical scavenging activity of olive leaf extract at different pH conditions: a spectroscopic and kinetic study.
    Journal of the science of food and agriculture, 2023, Mar-15, Volume: 103, Issue:4

    Topics: Antioxidants; Hot Temperature; Hydrogen-Ion Concentration; Iridoids; Olea; Phenols; Plant Extracts; Plant Leaves

2023
NOTCH1: A Novel Player in the Molecular Crosstalk Underlying Articular Chondrocyte Protection by Oleuropein and Hydroxytyrosol.
    International journal of molecular sciences, 2023, Mar-18, Volume: 24, Issue:6

    Topics: Cartilage, Articular; Cells, Cultured; Chondrocytes; Humans; Lipopolysaccharides; Osteoarthritis; Receptor, Notch1

2023
Comparative study of the effect of oleuropein and hydroxytyrosol rich extracts on the reproductive toxicity induced by bisphenol A in male rats: biochemical, histopathological, and molecular analyses.
    Environmental science and pollution research international, 2023, Volume: 30, Issue:32

    Topics: Animals; bcl-2-Associated X Protein; Iridoids; Male; Plant Extracts; Rats; Rats, Wistar; Tumor Suppressor Protein p53

2023
Anti-Inflammatory Effects of Nutritionally Relevant Concentrations of Oleuropein and Hydroxytyrosol on Peripheral Blood Mononuclear Cells: An Age-Related Analysis.
    International journal of molecular sciences, 2023, Jul-03, Volume: 24, Issue:13

    Topics: Adolescent; Adult; Aged; Humans; Leukocytes, Mononuclear; Lipopolysaccharides; Middle Aged; Phenylethyl Alcohol; Polyphenols; Young Adult

2023