3,4-dihydroxyphenylethanol has been researched along with oleuropein in 114 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (2.63) | 18.2507 |
| 2000's | 27 (23.68) | 29.6817 |
| 2010's | 57 (50.00) | 24.3611 |
| 2020's | 27 (23.68) | 2.80 |
| Authors | Studies |
|---|---|
| Deguin, B; Halabalaki, M; Lemus, C; Michel, S; Pergola, C; Skaltsounis, L; Smith, AB; Vougogiannopoulou, K; Werz, O | 1 |
| Aligiannis, N; Argyropoulou, A; Christoforidou, N; Gaboriaud-Kolar, N; Ioannou, K; Lemus, C; Paronis, E; Samara, P; Skaltsounis, AL; Tsitsilonis, O; Vougogiannopoulou, K | 1 |
| Blasevich, M; Galli, C; Montedoro, GF; Papini, N; Petroni, A; Salami, M | 1 |
| de la Puerta, R; Hoult, JR; Ruiz Gutierrez, V | 1 |
| Bisignano, G; Crisafi, G; Lo Cascio, R; Saija, A; Tomaino, A; Uccella, N | 1 |
| Catalá, A; de la Puerta, R; Gutierrez, VR | 1 |
| de la Puerta, R; Flavill, JA; Hoult, JR; Martínez Domínguez, ME; Ruíz-Gutíerrez, V | 1 |
| Briante, R; Febbraio, F; La Cara, F; Nucci, R; Patumi, M | 1 |
| Katan, MB; Leenen, R; Roodenburg, AJ; Vissers, MN; Zock, PL | 1 |
| Hayball, PJ; Kirlich, A; Stupans, I; Tuck, KL | 1 |
| Fregapane, G; Gómez-Alonso, S; Salvador, MD | 1 |
| Celli, N; De Curtis, A; Del Boccio, P; Di Deo, A; Iacoviello, L; Rotilio, D | 1 |
| Hayball, PJ; Stupans, I; Tan, HW; Tuck, KL | 1 |
| Ancora, MA; Carluccio, MA; De Caterina, R; Distante, A; Massaro, M; Scoditti, E; Siculella, L; Storelli, C; Visioli, F | 1 |
| Covas, MI; de la Torre, R; Farre, M; Fito, M; Miro-Casas, E; Ortuño, J; Roset, P; Weinbrenner, T | 1 |
| Caruso, D; Colonnelli, K; Galli, C; Galli, G; Grande, S; Patelli, C; Visioli, F | 1 |
| d'Ischia, M; Giudicianni, I; Napolitano, A; Panzella, L; Paolillo, L; Sacchi, R; Savarese, M | 1 |
| Gordon, MH; Paiva-Martins, F | 1 |
| Alonso, MG; de Pascual-Teresa, S; Etienne, N; Minihane, AM; Rimbach, G; Turner, R; Weinberg, PD | 1 |
| Agalias, A; Aligiannis, N; Bazios, D; Doulias, PT; Galaris, D; Mitakou, S; Nousis, L | 1 |
| Bosisio, E; Caruso, D; Crestani, M; De Fabiani, E; Dell'Agli, M; Fagnani, R; Galli, GV; Masciadri, M; Mitro, N; Mussoni, L; Scurati, S; Tremoli, E | 1 |
| Corsetti, A; Esposto, S; Massitti, O; Montedoro, GF; Servili, M; Settanni, L; Taticchi, A; Urbani, S; Veneziani, G | 1 |
| Bao, J; Chang, YT; Huang, PL; Lee, JW; Lee-Huang, S; Sun, Y; Zhang, D; Zhang, J | 2 |
| Bernini, R; Gambacorta, A; Migliorini, A; Tofani, D | 1 |
| Bao, J; Huang, PL; Lee-Huang, S; Zhang, DW; Zhang, JZ | 1 |
| Brenes, M; de Castro, A; García, A; Medina, E; Romero, C | 1 |
| Bouaziz, M; El Feki, A; Fki, I; Jemai, H; Sayadi, S | 1 |
| Papoti, VT; Tsimidou, MZ | 1 |
| Fregapane, G; Gómez-Rico, A; Inarejos-García, AM; Salvador, MD | 1 |
| Amado, F; Belo, L; Borges, F; Fernandes, J; Nascimento, H; Paiva-Martins, F; Rocha, S; Santos-Silva, A; Vitorino, R | 1 |
| El Feki, A; Jemai, H; Sayadi, S | 1 |
| Gikas, E; Magiatis, P; Melliou, E; Skaltsounis, AL; Tsarbopoulos, A; Zoidou, E | 1 |
| Andò, S; Casaburi, I; Chimento, A; De Luca, A; Iacopetta, D; Maggiolini, M; Onofrio, A; Pezzi, V; Puoci, F; Rizza, P; Sirianni, R | 1 |
| Ortega-García, F; Peragón, J | 1 |
| Calheiros, R; Marques, MP; Paiva-Martins, F; Rodrigues, V | 1 |
| Araki, M; Goto, T; Hagiwara, H; Hagiwara, K; Miyazaki, H | 1 |
| Chen, S; Drira, R; Sakamoto, K | 1 |
| Andújar, I; Cerdá-Nicolás, JM; Giner, E; Giner, RM; Recio, MC; Ríos, JL | 1 |
| Charoenprasert, S; Mitchell, A | 1 |
| Castro, PM; Kalogerakis, N; Piccirillo, C; Pintado, ME; Santos, MM | 1 |
| Giannakoula, A; Koundouras, S; Petridis, A; Samouris, G; Therios, I | 1 |
| Constantinou, AI; Odiatou, EM; Skaltsounis, AL | 1 |
| Alarcón de la Lastra, C; Cárdeno, A; Rosillo, MA; Sánchez-Hidalgo, M | 1 |
| Cutfield, WS; de Bock, M; Derraik, JG; Henderson, HV; Hofman, PL; Thorstensen, EB | 1 |
| Avena, P; Campana, C; Casaburi, I; Chimento, A; De Luca, A; Maggiolini, M; Martire, E; Pezzi, V; Rosano, C; Santolla, MF; Sirianni, R | 1 |
| Gnoni, GV; Priore, P; Siculella, L | 1 |
| Catalán, Ú; Farràs, M; Macià, A; Martín-Peláez, S; Mosele, JI; Motilva, MJ; Valls, RM | 1 |
| Fogal, TH; Mariani, ML; Penissi, AB; Persia, FA | 1 |
| Bulotta, S; Celano, M; Lepore, SM; Montalcini, T; Pujia, A; Russo, D | 1 |
| Bali, EB; Bayraktar, O; Ergin, V; Karasu, Ç; Küçükboyaci, N; Rackova, L | 1 |
| Tao, R; Wang, CZ; Ye, JZ; Yuan, JJ; Zhang, YS | 1 |
| Castañeda-Saucedo, MC; de la Serrana, HL; Ramírez-Anaya, Jdel P; Samaniego-Sánchez, C; Villalón-Mir, M | 1 |
| Golan-Goldhirsh, A; Gopas, J; Osheroff, N; Sedgeman, CA; Vann, KR | 1 |
| Koike, T; Matsuo, T; Murotomi, K; Nakajima, Y; Takashima, M; Umeno, A; Yoshida, Y | 1 |
| Bouallagui, Z; Hadrich, F; Isoda, H; Junkyu, H; Sayadi, S | 1 |
| Gikas, E; Lemonakis, N; Skaltsounis, AL; Tsarbopoulos, A | 1 |
| Jazayeri, JA; John, G; Lim, A; Obied, HK; Subhan, N; Vanniasinkam, T | 1 |
| Brenes, M; García, P; Medina, E; Ramírez, E; Romero, C | 1 |
| Amiot, MJ; Coxam, V; Georgé, S; Goncalves, A; Lebecque, P; Margier, M; Reboul, E; Tagliaferri, C; Wittrant, Y | 1 |
| Kopjar, N; Kosalec, I; Kraljić, K; Oršolić, N; Tomić, S; Zorić, N | 1 |
| Cicerale, S; Parkinson, L | 1 |
| Morales, FJ; Navarro, M; Ramos, S | 1 |
| Bauduin, P; Diat, O; Fadel, O; Girard, L; Gomes Rodrigues, D; L'Hermitte, A; Le Goff, X; Rossignol-Castera, A | 1 |
| Hauser, C; Kohnen, S; Thielmann, J | 1 |
| Frost, B; Liu, J; Sun, W | 1 |
| Finamore, A; Monteleone, JI; Palmeri, R; Restuccia, C; Serafini, M; Siracusa, L; Spagna, G; Sperlinga, E | 1 |
| Bedouhene, S; Dang, PM; El-Benna, J; Moulti-Mati, F | 1 |
| Fuentes, E; Jimenez, P; Ortiz, J; Paucar, F; Romero, N; Tapia, F | 1 |
| Bonacci, S; Cariati, L; Costanzo, P; Nardi, M; Oliverio, M; Procopio, A | 1 |
| Chen, A; Feng, Q; Wu, L; Xu, C; Xu, Y | 1 |
| Liu, M; Yong, Q; Yu, S | 1 |
| Aponte, M; Blaiotta, G; Calignano, A; d'Angelo, I; Dal Piaz, F; De Caro, C; Miro, A; Russo, R; Ungaro, F | 1 |
| Ayadi, L; Bouallagui, Z; Feki, I; Ghorbel, H; Guermazi, F; Mahmoudi, A; Sayadi, S | 1 |
| Argiriou, A; Makris, A; Mougiou, N; Trantas, E; Trikka, F; Ververidis, F; Vlachonasios, KE | 1 |
| Bouallagui, Z; Feki, I; Fourati, H; Ghorbel, H; Hadrich, F; Mahmoudi, A; Marrekchi, R; Sayadi, S | 1 |
| Amir, RM; Gilani, SA; Imran, M; Khan, S; Nadeem, M; Sajid, MW | 1 |
| Bonofiglio, M; Bonofiglio, R; Giordano, F; La Russa, A; Lofaro, D; Lupinacci, S; Parisi, OI; Perri, A; Puoci, F; Toteda, G; Vizza, D | 1 |
| Alkhatib, A; Tsang, C; Tuomilehto, J | 1 |
| Bond, DR; Goldsmith, CD; Jankowski, H; Roach, PD; Scarlett, CJ; Stathopoulos, CE; Weidenhofer, J | 1 |
| Aree, T; Jongrungruangchok, S | 1 |
| Ali Ahmed, S; Boumendjel, M; Houali, K; Lahcene, S; Mestar, N; Ouafi, S; Taibi, F | 1 |
| Leal-Hernandez, O; Moran, JM; Pedrera-Zamorano, JD; Roncero-Martin, R | 1 |
| Cabrera-Bañegil, M; Delgado-Adámez, J; Fernández, A; Lodolini, EM; Martín-Vertedor, D; Ramírez, R | 1 |
| Chehab, H; Hammami, M; Mechri, B; Tekaya, M | 1 |
| Huang, C; Lian, Z; Liu, M; Yong, Q; Yu, S | 1 |
| Ding, T; Huan, F; Jiang, S; Long, YF; Lu, HY; Shen, WJ; Wang, SL; Wu, B; Zhang, Z; Zhu, JS | 1 |
| Guodong, R; Jianguo, Z; Xiaoxia, L; Ying, L | 1 |
| Tian, M; Wen, M; Zhang, L; Zhang, Y; Zhou, J; Zhou, P | 1 |
| Daoued, I; Fki, I; Ghorbel, H; Mahmoudi, A; Marrekchi, R; Sayadi, S | 1 |
| Ding, T; Jiang, S; Lu, HY; Shen, WJ; Wang, SL; Wu, B; Xie, J; Zhang, Z; Zhu, J; Zhu, JS | 1 |
| Chaari, A | 1 |
| Buiatti, S; Guglielmotti, M; Passaghe, P | 1 |
| Kopjar, N; Kosalec, I; Rodriguez, JV; Tomić, S; Zorić, N | 1 |
| Breakspear, I; Guillaume, C | 1 |
| Kalogiouri, NP; Kolyvira, L; Kritikou, E; Thomaidis, NS | 1 |
| Bonacci, S; Costanzo, P; Di Gioia, ML; Mancuso, S; Nardi, M; Oliverio, M; Procopio, A | 1 |
| Augello, G; Azzolina, A; Cervello, M; Cusimano, A; Di Stefano, V; Emma, MR; Giannitrapani, L; Montalto, G | 1 |
| Carrera-González, MP; Martínez-Martos, JM; Mayas, MD; Ramírez-Expósito, MJ | 1 |
| Díez-Pascual, AM; Sainz-Urruela, C; San Andrés, MP; Vera-López, S | 1 |
| Hioki, T; Iida, H; Kim, W; Kozawa, O; Kuroyanagi, G; Matsushima-Nishiwaki, R; Tachi, J; Tokuda, H | 1 |
| Akanji, T; Gutkowski, J; He, H; Li, D; Li, H; Li, R; Liu, C; Ma, H; Seeram, NP; Wan, Y; Wu, P | 1 |
| Chung, JS; Kwon, SM; Lee, DH; Ly, TTG; Yun, J | 1 |
| Ishimaru, K; Kotoda, N; Matsuo, Y; Nakayama, H; Nishi, N; Tanaka, T | 1 |
| Caggia, C; Cattivelli, A; Martini, S; Pino, A; Randazzo, CL; Solieri, L; Tagliazucchi, D; Vaccalluzzo, A | 1 |
| Angelis, A; Antoniadi, L; Chountoulesi, M; Demetzos, C; Halabalaki, M; Lei, J; Li, W; Mitakou, S; Skaltsounis, LA; Wang, C | 1 |
| Chatzikonstantinou, AV; Chochos, CL; Giannakopoulou, A; Houhoula, D; Stamatis, H; Tsakni, A | 1 |
| Di Mattia, CD; Gonzalez-Ortega, R; Natasa, PU; Pittia, P | 1 |
| Brocchini, S; Nardi, M; Procopio, A; Somavarapu, S | 1 |
| Accardi, G; Aiello, A; Allegra, M; Calabrò, A; Candore, G; Caruso, C; Gervasi, F; Ligotti, ME; Pojero, F; Procopio, A | 1 |
| Bissoli, I; Borzì, RM; Cetrullo, S; D'Adamo, S; Flamigni, F; Panichi, V | 1 |
| Bernini, R; Bertini, L; Bonato, A; Caruso, C; Caruso, M; Micheli, L; Tirone, F; Villanova, N | 1 |
| Ayadi, L; Bouallagui, Z; Chamkha, M; Feki, I; Ghorbel, H; Hadrich, F; Mahmoudi, A; Sayadi, S | 1 |
| Accardi, G; Aiello, A; Allegra, M; Attanzio, A; Bonacci, S; Caldarella, R; Candore, G; Caruso, C; Fiore, SD; Gervasi, F; Ligotti, ME; Pojero, F; Procopio, A; Restivo, I; Tesoriere, L | 1 |
13 review(s) available for 3,4-dihydroxyphenylethanol and oleuropein
| Article | Year |
|---|---|
Factors influencing phenolic compounds in table olives (Olea europaea).
Topics: Antioxidants; Diet, Mediterranean; Drug Stability; Flavonoids; Food Handling; Fruit; Health Promotion; Hot Temperature; Humans; Iridoid Glucosides; Iridoids; Olea; Phenol; Phenylethyl Alcohol; Pyrans; Seeds; Species Specificity | 2012 |
Beneficial effects of the olive oil phenolic components oleuropein and hydroxytyrosol: focus on protection against cardiovascular and metabolic diseases.
Topics: Animals; Cardiovascular Diseases; Diabetes Mellitus; Humans; Iridoid Glucosides; Iridoids; Metabolic Diseases; Olive Oil; Phenylethyl Alcohol; Plant Oils | 2014 |
The Health Benefiting Mechanisms of Virgin Olive Oil Phenolic Compounds.
Topics: Aldehydes; Animals; Anti-Inflammatory Agents; Biological Availability; Cyclopentane Monoterpenes; Dietary Supplements; Humans; Iridoid Glucosides; Iridoids; Olive Oil; Phenols; Phenylethyl Alcohol | 2016 |
Antimicrobial activity of Olea europaea Linné extracts and their applicability as natural food preservative agents.
Topics: Aldehydes; Anti-Infective Agents; Food Preservatives; Fruit; Iridoid Glucosides; Iridoids; Olea; Phenols; Phenylethyl Alcohol; Plant Extracts; Plant Leaves; Pyrans | 2017 |
Antitumor Perspectives of Oleuropein and Its Metabolite Hydroxytyrosol: Recent Updates.
Topics: Animals; Antineoplastic Agents; Cell Movement; Cell Proliferation; Coronary Disease; DNA Damage; Humans; Iridoid Glucosides; Iridoids; Neoplasm Invasiveness; Neoplasms; Neovascularization, Pathologic; Olea; Olive Oil; Phenylethyl Alcohol; Pyrans | 2018 |
Olive Oil Nutraceuticals in the Prevention and Management of Diabetes: From Molecules to Lifestyle.
Topics: Diabetes Mellitus, Type 2; Dietary Fats; Dietary Supplements; Humans; Iridoid Glucosides; Iridoids; Life Style; Olive Oil; Phenylethyl Alcohol | 2018 |
Semi-synthesis as a tool for broadening the health applications of bioactive olive secoiridoids: a critical review.
Topics: Aldehydes; Cyclopentane Monoterpenes; Iridoid Glucosides; Iridoids; Olea; Olive Oil; Phenols; Phenylethyl Alcohol | 2021 |
Potential Uses of Olive Oil Secoiridoids for the Prevention and Treatment of Cancer: A Narrative Review of Preclinical Studies.
Topics: Aldehydes; Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Antioxidants; Cyclopentane Monoterpenes; Diet, Mediterranean; Glucosides; Humans; Iridoid Glucosides; Iridoids; Neoplasms; Olive Oil; Phenols; Phenylethyl Alcohol; Pyrans | 2021 |
Graphene-Based Sensors for the Detection of Bioactive Compounds: A Review.
Topics: Antioxidants; Ascorbic Acid; Biosensing Techniques; Curcumin; Electric Conductivity; Electrodes; Free Radicals; Gallic Acid; Graphite; Humans; Iridoid Glucosides; Melatonin; Metals; Nanocomposites; Nanostructures; Oxides; Phenylethyl Alcohol; Quantum Dots; Resveratrol; Tannins; Tocopherols | 2021 |
Protective Effects and Benefits of Olive Oil and Its Extracts on Women's Health.
Topics: Animals; Diet, Healthy; Diet, Mediterranean; Female; Humans; Iridoid Glucosides; Olea; Olive Oil; Phenylethyl Alcohol; Plant Oils; Polyphenols; Protective Agents; Women's Health | 2021 |
Hydroxytyrosol oleate: A promising neuroprotective nanocarrier delivery system of oleuropein and derivatives.
Topics: Antioxidants; Humans; Male; Neuroblastoma; Olea; Oleic Acid; Olive Oil; Phenols; Phenylethyl Alcohol; Plant Oils | 2023 |
Effects of Oleuropein and Hydroxytyrosol on Inflammatory Mediators: Consequences on Inflammaging.
Topics: Antioxidants; Humans; Inflammation; Inflammation Mediators; Iridoid Glucosides; Iridoids; Olive Oil; Phenylethyl Alcohol | 2022 |
Role of Hydroxytyrosol and Oleuropein in the Prevention of Aging and Related Disorders: Focus on Neurodegeneration, Skeletal Muscle Dysfunction and Gut Microbiota.
Topics: Gastrointestinal Microbiome; Muscle, Skeletal; Olive Oil | 2023 |
1 trial(s) available for 3,4-dihydroxyphenylethanol and oleuropein
| Article | Year |
|---|---|
Human absorption and metabolism of oleuropein and hydroxytyrosol ingested as olive (Olea europaea L.) leaf extract.
Topics: Absorption; Adult; Antioxidants; Chromatography, Liquid; Dose-Response Relationship, Drug; Female; Humans; Iridoid Glucosides; Iridoids; Male; Middle Aged; Olea; Phenylethyl Alcohol; Plant Extracts; Plant Leaves; Polyphenols; Pyrans; Tandem Mass Spectrometry | 2013 |
100 other study(ies) available for 3,4-dihydroxyphenylethanol and oleuropein
| Article | Year |
|---|---|
One-step semisynthesis of oleacein and the determination as a 5-lipoxygenase inhibitor.
Topics: Aldehydes; Anti-Inflammatory Agents; Arachidonate 5-Lipoxygenase; Cyclopentane Monoterpenes; Glucosides; Humans; Iridoid Glucosides; Iridoids; Lipoxygenase Inhibitors; Molecular Structure; Olea; Phenols; Plant Extracts; Plant Leaves; Pyrans | 2014 |
New semi-synthetic analogs of oleuropein show improved anticancer activity in vitro and in vivo.
Topics: Animals; Antineoplastic Agents; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Iridoid Glucosides; Iridoids; Male; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Molecular Structure; Structure-Activity Relationship; Tumor Cells, Cultured | 2017 |
Inhibition of platelet aggregation and eicosanoid production by phenolic components of olive oil.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Adenosine Diphosphate; Antioxidants; Collagen; Eicosanoids; Flavonoids; Humans; Hydroxyeicosatetraenoic Acids; Iridoid Glucosides; Iridoids; Olive Oil; Phenylethyl Alcohol; Plant Extracts; Plant Oils; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyrans; Thromboxane B2 | 1995 |
Inhibition of leukocyte 5-lipoxygenase by phenolics from virgin olive oil.
Topics: Animals; Antioxidants; Caffeic Acids; Dietary Fats, Unsaturated; Eicosanoids; Iridoid Glucosides; Iridoids; Leukocytes; Lipoxygenase Inhibitors; Male; Olive Oil; Phenylethyl Alcohol; Plant Oils; Pyrans; Rats; Rats, Wistar; Reactive Oxygen Species | 1999 |
On the in-vitro antimicrobial activity of oleuropein and hydroxytyrosol.
Topics: Anti-Bacterial Agents; Bacteria; Dose-Response Relationship, Drug; In Vitro Techniques; Iridoid Glucosides; Iridoids; Microbial Sensitivity Tests; Phenylethyl Alcohol; Pyrans | 1999 |
The effect of tyrosol, hydroxytyrosol and oleuropein on the non-enzymatic lipid peroxidation of rat liver microsomes.
Topics: Animals; Cholesterol; Fatty Acids; Iridoid Glucosides; Iridoids; Lipid Peroxidation; Microsomes, Liver; Oxidation-Reduction; Phenylethyl Alcohol; Phospholipids; Pyrans; Rats; Rats, Wistar | 2001 |
Effects of virgin olive oil phenolics on scavenging of reactive nitrogen species and upon nitrergic neurotransmission.
Topics: Animals; Antioxidants; Caffeic Acids; Dose-Response Relationship, Drug; Free Radical Scavengers; Iridoid Glucosides; Iridoids; Male; Muscle Relaxation; Muscle, Smooth; Neural Conduction; Nitrates; Nitric Oxide; Nitroprusside; Olive Oil; Phenols; Phenylethyl Alcohol; Plant Oils; Pyrans; Rats; Rats, Wistar | 2001 |
Bioactive derivatives from oleuropein by a biotransformation on Olea europaea leaf extracts.
Topics: Antioxidants; Bioreactors; Biotransformation; Chromatography, Gas; Chromatography, High Pressure Liquid; Colorimetry; Iridoid Glucosides; Iridoids; Lipid Peroxidation; Oleaceae; Phenylethyl Alcohol; Plant Extracts; Plant Leaves; Pyrans | 2002 |
Olive oil phenols are absorbed in humans.
Topics: Absorption; Adult; Colon; Dietary Supplements; Drug Stability; Female; Humans; Ileostomy; Iridoid Glucosides; Iridoids; Male; Olive Oil; Phenols; Phenylethyl Alcohol; Placebos; Plant Oils; Pyrans | 2002 |
Comparison of radical scavenging effect, inhibition of microsomal oxygen free radical generation, and serum lipoprotein oxidation of several natural antioxidants.
Topics: Animals; Antioxidants; Aryl Hydrocarbon Hydroxylases; Bepridil; Biphenyl Compounds; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Free Radical Scavengers; Gallic Acid; Humans; Iridoid Glucosides; Iridoids; Lipid Peroxidation; Lipoproteins, LDL; Male; Microsomes, Liver; Olive Oil; Oxidoreductases, N-Demethylating; Phenylethyl Alcohol; Picrates; Plant Oils; Pyrans; Rats; Rats, Wistar; Reactive Oxygen Species; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases | 2002 |
Phenolic compounds profile of cornicabra virgin olive oil.
Topics: Chromatography, High Pressure Liquid; Colorimetry; Drug Stability; Flavonoids; Iridoid Glucosides; Iridoids; Olive Oil; Oxidation-Reduction; Phenols; Phenylethyl Alcohol; Plant Oils; Polymers; Polyphenols; Pyrans; Seasons | 2002 |
Liquid chromatography-tandem mass spectrometry analysis of oleuropein and its metabolite hydroxytyrosol in rat plasma and urine after oral administration.
Topics: Administration, Oral; Animals; Calibration; Iridoid Glucosides; Iridoids; Phenylethyl Alcohol; Pyrans; Rats; Sensitivity and Specificity | 2003 |
Simultaneous determination of oleuropein and hydroxytyrosol in rat plasma using liquid chromatography with fluorescence detection.
Topics: Animals; Calibration; Chromatography, High Pressure Liquid; Iridoid Glucosides; Iridoids; Phenylethyl Alcohol; Pyrans; Rats; Sensitivity and Specificity; Spectrometry, Fluorescence | 2003 |
Olive oil and red wine antioxidant polyphenols inhibit endothelial activation: antiatherogenic properties of Mediterranean diet phytochemicals.
Topics: Animals; Antioxidants; Arteriosclerosis; Cattle; Cell Adhesion; Cells, Cultured; Diet; Endothelium, Vascular; Flavonoids; Gene Expression Regulation; Humans; Iridoid Glucosides; Iridoids; NF-kappa B; Olive Oil; Phenols; Phenylethyl Alcohol; Plant Oils; Polyphenols; Pyrans; Resveratrol; RNA, Messenger; Stilbenes; Transcription Factor AP-1; Transcription, Genetic; U937 Cells; Vascular Cell Adhesion Molecule-1; Wine | 2003 |
Hydroxytyrosol disposition in humans.
Topics: Adult; Antioxidants; Female; Gas Chromatography-Mass Spectrometry; Humans; Iridoid Glucosides; Iridoids; Male; Middle Aged; Olive Oil; Phenylethyl Alcohol; Plant Oils; Pyrans | 2003 |
Hydroxytyrosol excretion differs between rats and humans and depends on the vehicle of administration.
Topics: Animals; Antioxidants; Drug Combinations; Humans; Hydrolysis; Iridoid Glucosides; Iridoids; Olive Oil; Pharmaceutical Vehicles; Phenylethyl Alcohol; Plant Oils; Pyrans; Rats; Species Specificity; Yogurt | 2003 |
Acid-induced structural modifications of unsaturated Fatty acids and phenolic olive oil constituents by nitrite ions: a chemical assessment.
Topics: Acids; Alkenes; Antineoplastic Agents; Fatty Acids, Unsaturated; Gas Chromatography-Mass Spectrometry; Hydrogen-Ion Concentration; Ions; Iridoid Glucosides; Iridoids; Isomerism; Magnetic Resonance Spectroscopy; Nitrites; Nitrosation; Olive Oil; Phenols; Phenylethyl Alcohol; Plant Oils; Pyrans | 2004 |
Interactions of ferric ions with olive oil phenolic compounds.
Topics: Drug Stability; Ferric Compounds; Hydrogen-Ion Concentration; Iridoid Glucosides; Iridoids; Olive Oil; Phenols; Phenylethyl Alcohol; Plant Oils; Pyrans | 2005 |
Antioxidant and anti-atherogenic activities of olive oil phenolics.
Topics: Antioxidants; Arteriosclerosis; Cell Adhesion Molecules; Cells, Cultured; Chemokine CCL2; Endothelium; Homovanillic Acid; Hydrogen Peroxide; In Vitro Techniques; Intercellular Adhesion Molecule-1; Iridoid Glucosides; Iridoids; Lipoproteins, LDL; Macrophages; Nitric Oxide; Olive Oil; Phenols; Phenylethyl Alcohol; Plant Oils; Platelet Aggregation; Pyrans; Vascular Cell Adhesion Molecule-1 | 2005 |
DNA protecting and genotoxic effects of olive oil related components in cells exposed to hydrogen peroxide.
Topics: Caffeic Acids; Chromatography, High Pressure Liquid; Comet Assay; DNA; DNA Damage; Humans; Hydrogen Peroxide; Iridoid Glucosides; Iridoids; Jurkat Cells; Nuclear Magnetic Resonance, Biomolecular; Olea; Olive Oil; Phenylethyl Alcohol; Plant Extracts; Plant Oils; Pyrans | 2005 |
Minor components of olive oil modulate proatherogenic adhesion molecules involved in endothelial activation.
Topics: Cell Adhesion Molecules; E-Selectin; Endothelium, Vascular; Gene Expression; Humans; Intercellular Adhesion Molecule-1; Iridoid Glucosides; Iridoids; Olive Oil; Phenylethyl Alcohol; Plant Oils; Pyrans; RNA, Messenger; Umbilical Veins; Vascular Cell Adhesion Molecule-1 | 2006 |
The use of Lactobacillus pentosus 1MO to shorten the debittering process time of black table olives (Cv. Itrana and Leccino): a pilot-scale application.
Topics: Fermentation; Food Handling; Fruit; Hydrogen-Ion Concentration; Iridoid Glucosides; Iridoids; Lactobacillus; Olea; Phenols; Phenylethyl Alcohol; Pyrans; Taste | 2006 |
Discovery of small-molecule HIV-1 fusion and integrase inhibitors oleuropein and hydroxytyrosol: part II. integrase inhibition.
Topics: Catalytic Domain; HIV Integrase; HIV Integrase Inhibitors; Iridoid Glucosides; Iridoids; Models, Molecular; Phenylethyl Alcohol; Pyrans; Structure-Activity Relationship | 2007 |
Discovery of small-molecule HIV-1 fusion and integrase inhibitors oleuropein and hydroxytyrosol: Part I. fusion [corrected] inhibition.
Topics: Chromatography, Liquid; Circular Dichroism; Electrophoresis, Polyacrylamide Gel; HIV Envelope Protein gp41; HIV Integrase Inhibitors; HIV-1; Iridoid Glucosides; Iridoids; Mass Spectrometry; Models, Molecular; Phenylethyl Alcohol; Pyrans | 2007 |
High-yielding preparation of a stable precursor of hydroxytyrosol by total synthesis and from the natural glycoside oleuropein.
Topics: Antioxidants; Drug Stability; Food Additives; Iridoid Glucosides; Iridoids; Phenylethyl Alcohol; Pyrans | 2007 |
Computational study of bindings of olive leaf extract (OLE) to HIV-1 fusion protein gp41.
Topics: Antiviral Agents; Computer Simulation; HIV Envelope Protein gp41; HIV-1; Humans; Hydrogen Bonding; Iridoid Glucosides; Iridoids; Models, Molecular; Molecular Structure; Olea; Phenylethyl Alcohol; Plant Extracts; Plant Leaves; Protein Binding; Pyrans; Thermodynamics | 2007 |
Main antimicrobial compounds in table olives.
Topics: Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Fermentation; Iridoid Glucosides; Iridoids; Lactobacillus; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Olea; Phenylethyl Alcohol; Pyrans; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet | 2007 |
Hypolipidimic and antioxidant activities of oleuropein and its hydrolysis derivative-rich extracts from Chemlali olive leaves.
Topics: Animals; Antioxidants; beta-Glucosidase; Catalase; Cholesterol, Dietary; Enzyme Activation; Heart; Hydrochloric Acid; Hydrolysis; Hypercholesterolemia; Iridoid Glucosides; Iridoids; Lipid Peroxidation; Lipids; Liver; Male; Molecular Structure; Olea; Organ Size; Phenylethyl Alcohol; Plant Extracts; Plant Leaves; Pyrans; Rats; Rats, Wistar; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances | 2008 |
Impact of sampling parameters on the radical scavenging potential of olive (Olea europaea L.) leaves.
Topics: Flavonoids; Free Radical Scavengers; Iridoid Glucosides; Iridoids; Olea; Phenols; Phenylethyl Alcohol; Plant Extracts; Plant Leaves; Pyrans; Species Specificity; Time Factors | 2009 |
Effect of malaxation conditions on phenol and volatile profiles in olive paste and the corresponding virgin olive oils (Olea europaea L. Cv. Cornicabra).
Topics: Aldehydes; Consumer Behavior; Food Handling; Fruit; Iridoid Glucosides; Iridoids; Olea; Olive Oil; Phenols; Phenylethyl Alcohol; Plant Oils; Pyrans; Temperature; Volatilization | 2009 |
Effects of olive oil polyphenols on erythrocyte oxidative damage.
Topics: Adult; Amino Acid Sequence; Erythrocytes; Female; Flavonoids; Humans; Iridoid Glucosides; Iridoids; Male; Membrane Proteins; Middle Aged; Molecular Sequence Data; Olive Oil; Phenols; Phenylethyl Alcohol; Plant Oils; Polyphenols; Pyrans | 2009 |
Antidiabetic and antioxidant effects of hydroxytyrosol and oleuropein from olive leaves in alloxan-diabetic rats.
Topics: Animals; Antioxidants; Blood Glucose; Diabetes Mellitus, Experimental; Hypoglycemic Agents; Iridoid Glucosides; Iridoids; Liver; Male; Olea; Oxidative Stress; Phenylethyl Alcohol; Phytotherapy; Plant Extracts; Plant Leaves; Pyrans; Rats; Rats, Wistar | 2009 |
Identification of Throuba Thassos, a traditional Greek table olive variety, as a nutritional rich source of oleuropein.
Topics: Food Handling; Greece; Humans; Iridoid Glucosides; Iridoids; Nutritive Value; Olea; Phenylethyl Alcohol; Pyrans | 2010 |
Oleuropein and hydroxytyrosol inhibit MCF-7 breast cancer cell proliferation interfering with ERK1/2 activation.
Topics: Anticarcinogenic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Enzyme Activation; Estradiol; Estrogen Receptor alpha; Female; Humans; Iridoid Glucosides; Iridoids; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phenylethyl Alcohol; Protein Kinase Inhibitors; Pyrans; Transcriptional Activation | 2010 |
HPLC analysis of oleuropein, hydroxytyrosol, and tyrosol in stems and roots of Olea europaea L. cv. Picual during ripening.
Topics: Antioxidants; Chromatography, High Pressure Liquid; Fruit; Iridoid Glucosides; Iridoids; Olea; Phenylethyl Alcohol; Plant Leaves; Plant Roots; Plant Stems; Pyrans; Seasons; Spain; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2010 |
Characterization of antioxidant olive oil biophenols by spectroscopic methods.
Topics: Antioxidants; Iridoid Glucosides; Iridoids; Olea; Olive Oil; Phenols; Phenylethyl Alcohol; Plant Oils; Pyrans; Spectrum Analysis, Raman | 2011 |
Olive polyphenol hydroxytyrosol prevents bone loss.
Topics: 3T3 Cells; Animals; Female; Flavonoids; Humans; Iridoid Glucosides; Iridoids; Male; Mice; Olea; Osteoblasts; Osteoclasts; Osteogenesis; Osteoporosis; Ovariectomy; Phenols; Phenylethyl Alcohol; Polyphenols; Pyrans | 2011 |
Oleuropein and hydroxytyrosol inhibit adipocyte differentiation in 3 T3-L1 cells.
Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Animals; Antioxidants; Cell Differentiation; Cell Survival; Dose-Response Relationship, Drug; Down-Regulation; Flow Cytometry; Iridoid Glucosides; Iridoids; Mice; Mitosis; Phenylethyl Alcohol; Pyrans; Reverse Transcriptase Polymerase Chain Reaction; Triglycerides | 2011 |
Oleuropein ameliorates acute colitis in mice.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Colitis; Cytokines; Dextran Sulfate; Female; Iridoid Glucosides; Iridoids; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; Nitric Oxide; Phenylethyl Alcohol; Pyrans | 2011 |
Bioconversion of oleuropein to hydroxytyrosol by lactic acid bacteria.
Topics: Iridoid Glucosides; Iridoids; Lactobacillus; Olea; Phenylethyl Alcohol; Pyrans | 2012 |
Effect of water deficit on leaf phenolic composition, gas exchange, oxidative damage and antioxidant activity of four Greek olive (Olea europaea L.) cultivars.
Topics: Agricultural Irrigation; Antioxidants; Chlorophyll; Chlorophyll A; Dehydration; Genotype; Iridoid Glucosides; Iridoids; Lipid Peroxidation; Malondialdehyde; Olea; Oxidative Stress; Phenols; Phenylethyl Alcohol; Photosynthesis; Plant Leaves; Plant Roots; Plant Transpiration; Pyrans; Stress, Physiological | 2012 |
Identification of the factors responsible for the in vitro pro-oxidant and cytotoxic activities of the olive polyphenols oleuropein and hydroxytyrosol.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Culture Media; Female; Humans; Hydrogen Peroxide; Iridoid Glucosides; Iridoids; Mice; Olea; Oxidants; Oxidative Stress; Phenylethyl Alcohol; Plant Extracts; Plant Oils; Pyrans; Reactive Oxygen Species | 2013 |
Oleuropein, a secoiridoid derived from olive tree, inhibits the proliferation of human colorectal cancer cell through downregulation of HIF-1α.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Cycle; Cell Proliferation; Colorectal Neoplasms; Down-Regulation; HT29 Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; I-kappa B Proteins; Iridoid Glucosides; Iridoids; NF-kappa B; NF-KappaB Inhibitor alpha; Olea; p38 Mitogen-Activated Protein Kinases; Phenylethyl Alcohol; PPAR gamma; Pyrans; Tumor Suppressor Protein p53 | 2013 |
Oleuropein and hydroxytyrosol activate GPER/ GPR30-dependent pathways leading to apoptosis of ER-negative SKBR3 breast cancer cells.
Topics: Apoptosis; Breast Neoplasms; Cell Proliferation; Extracellular Signal-Regulated MAP Kinases; Female; Humans; Iridoid Glucosides; Iridoids; Phenylethyl Alcohol; Receptors, Estrogen; Receptors, G-Protein-Coupled; Signal Transduction; Tumor Cells, Cultured | 2014 |
Extra virgin olive oil phenols down-regulate lipid synthesis in primary-cultured rat-hepatocytes.
Topics: Acetyl-CoA Carboxylase; AMP-Activated Protein Kinases; Animals; Cells, Cultured; Cholesterol; Diacylglycerol O-Acyltransferase; Down-Regulation; Fatty Acids; Hepatocytes; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Iridoid Glucosides; Iridoids; Lipids; Lipogenesis; Male; Olive Oil; Phenylethyl Alcohol; Phosphorylation; Plant Oils; Rats, Wistar | 2014 |
Faecal microbial metabolism of olive oil phenolic compounds: in vitro and in vivo approaches.
Topics: Acetates; Catechols; Colon; Feces; Fermentation; Humans; In Vitro Techniques; Iridoid Glucosides; Iridoids; Kinetics; Microbiota; Nontherapeutic Human Experimentation; Olive Oil; Phenols; Phenylethyl Alcohol; Plant Oils | 2014 |
Hydroxytyrosol and oleuropein of olive oil inhibit mast cell degranulation induced by immune and non-immune pathways.
Topics: Animals; beta-N-Acetylhexosaminidases; Cell Degranulation; Dose-Response Relationship, Drug; Iridoid Glucosides; Iridoids; Male; Mast Cells; Olive Oil; Phenylethyl Alcohol; Plant Oils; Rats, Wistar | 2014 |
Olive leaf extracts protect cardiomyocytes against 4-hydroxynonenal-induced toxicity in vitro: comparison with oleuropein, hydroxytyrosol, and quercetin.
Topics: Aldehydes; Animals; Antioxidants; Caspase 3; Cell Survival; In Vitro Techniques; Iridoid Glucosides; Iridoids; Mitochondria; Myocytes, Cardiac; Olea; Oxidative Stress; Phenylethyl Alcohol; Plant Extracts; Plant Leaves; Polyphenols; Protective Agents; Protein Serine-Threonine Kinases; Quercetin; Rats; Transcription Factors | 2014 |
Enzymatic hydrolysis of oleuropein from Olea europea (olive) leaf extract and antioxidant activities.
Topics: Antioxidants; Biotransformation; Hydrolysis; Iridoid Glucosides; Iridoids; Olea; Phenylethyl Alcohol; Plant Extracts; Plant Leaves; Pyrans | 2015 |
Phenols and the antioxidant capacity of Mediterranean vegetables prepared with extra virgin olive oil using different domestic cooking techniques.
Topics: Antioxidants; Benzothiazoles; Chlorogenic Acid; Chromatography, High Pressure Liquid; Cluster Analysis; Cooking; Cucurbita; Dietary Fats; Furans; Iridoid Glucosides; Iridoids; Lignans; Multivariate Analysis; Olive Oil; Phenols; Phenylethyl Alcohol; Rutin; Solanum lycopersicum; Solanum melongena; Solanum tuberosum; Sulfonic Acids; Vegetables | 2015 |
Effects of Olive Metabolites on DNA Cleavage Mediated by Human Type II Topoisomerases.
Topics: DNA Cleavage; DNA Topoisomerases, Type II; Drug Screening Assays, Antitumor; Fruit; Glucosides; Humans; Iridoid Glucosides; Iridoids; Olea; Phenols; Phenylethyl Alcohol; Plant Bark; Plant Extracts; Plant Leaves; Plasmids; Topoisomerase II Inhibitors | 2015 |
Radical-scavenging Activity and Antioxidative Effects of Olive Leaf Components Oleuropein and Hydroxytyrosol in Comparison with Homovanillic Alcohol.
Topics: Antioxidants; Chromans; Free Radical Scavengers; Homovanillic Acid; Iridoid Glucosides; Iridoids; Linoleic Acids; Lipid Peroxidation; Micelles; Olea; Oxidation-Reduction; Phenylethyl Alcohol; Plant Leaves | 2015 |
The α-Glucosidase and α-Amylase Enzyme Inhibitory of Hydroxytyrosol and Oleuropein.
Topics: alpha-Amylases; alpha-Glucosidases; Caco-2 Cells; Cell Survival; Dose-Response Relationship, Drug; Glycoside Hydrolase Inhibitors; Humans; Hyperglycemia; Iridoid Glucosides; Iridoids; Olea; Phenylethyl Alcohol; Phytotherapy; Plant Leaves | 2015 |
Optimization of parameters affecting signal intensity in an LTQ-orbitrap in negative ion mode: A design of experiments approach.
Topics: Iridoid Glucosides; Iridoids; Phenylethyl Alcohol; Spectrometry, Mass, Electrospray Ionization; Syringes | 2016 |
Plant Phenols as Antibiotic Boosters: In Vitro Interaction of Olive Leaf Phenols with Ampicillin.
Topics: Ampicillin; Anti-Bacterial Agents; Bacteria; Caffeic Acids; Drug Synergism; Escherichia coli; Flavones; Glucosides; Herb-Drug Interactions; Iridoid Glucosides; Iridoids; Medicine, Traditional; Olea; Phenols; Phenylethyl Alcohol; Plant Extracts; Plant Leaves; Staphylococcus aureus | 2016 |
Oleuropein hydrolysis in natural green olives: Importance of the endogenous enzymes.
Topics: beta-Glucosidase; Esterases; Food Handling; Food Storage; Hot Temperature; Hydrogen-Ion Concentration; Hydrolysis; Iridoid Glucosides; Iridoids; Olea; Phenols; Phenylethyl Alcohol; Pyrans; Salts; Taste | 2016 |
Pinoresinol of olive oil decreases vitamin D intestinal absorption.
Topics: Animals; Caco-2 Cells; Docosahexaenoic Acids; Female; Furans; Humans; Intestinal Absorption; Iridoid Glucosides; Iridoids; Lignans; Olive Oil; Phenylethyl Alcohol; Polyphenols; Rats; Rats, Wistar; Vitamin D | 2016 |
Olive leaf extract activity against Candida albicans and C. dubliniensis - the in vitro viability study.
Topics: Anti-Bacterial Agents; Antifungal Agents; Antioxidants; Candida; Candida albicans; Cell Nucleus; Cell Nucleus Shape; Chromatography, High Pressure Liquid; Coloring Agents; Fluorescent Dyes; Iridoid Glucosides; Iridoids; Microbial Sensitivity Tests; Olea; Phenylethyl Alcohol; Plant Extracts; Plant Leaves; Trypan Blue | 2016 |
Olive leaf extract concentrated in hydroxytyrosol attenuates protein carbonylation and the formation of advanced glycation end products in a hepatic cell line (HepG2).
Topics: Antioxidants; Glycation End Products, Advanced; Hep G2 Cells; Hepatocytes; Humans; Iridoid Glucosides; Iridoids; Olea; Phenylethyl Alcohol; Plant Extracts; Plant Leaves; Protein Carbonylation | 2017 |
Micellization in vegetable oils: A structural characterisation.
Topics: Antioxidants; Benzhydryl Compounds; Cosmetics; Emulsifying Agents; Flavones; Glucosides; Glycerol; Humans; Iridoid Glucosides; Iridoids; Micelles; Phenylethyl Alcohol; Plant Oils; Solubility; Stearic Acids; Waxes | 2017 |
Oleuropein, unexpected benefits!
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Blood Pressure; Diet, Mediterranean; Humans; Hypertension; Iridoid Glucosides; Iridoids; Mice; Olea; Oxidative Stress; Parkinson Disease; Phenylethyl Alcohol; Rats | 2017 |
Bioactivity Improvement of Olea europaea Leaf Extract Biotransformed by Wickerhamomyces anomalus Enzymes.
Topics: beta-Glucosidase; Biotransformation; Caco-2 Cells; Coumaric Acids; Esterases; Humans; Hydrolysis; Iridoid Glucosides; Iridoids; Olea; Phenols; Phenylethyl Alcohol; Plant Leaves; Polyphenols; Saccharomycetales | 2017 |
Oleuropein and hydroxytyrosol inhibit the N-formyl-methionyl-leucyl-phenylalanine-induced neutrophil degranulation and chemotaxis via AKT, p38, and ERK1/2 MAP-Kinase inhibition.
Topics: Anti-Inflammatory Agents; Chemotaxis; Humans; Iridoid Glucosides; Iridoids; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phenylethyl Alcohol; Phosphorylation; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Signal Transduction | 2017 |
Effect of the composition of extra virgin olive oils on the differentiation and antioxidant capacities of twelve monovarietals.
Topics: Agriculture; Antioxidants; Chile; Food Analysis; Furans; Glucosides; Iridoid Glucosides; Iridoids; Least-Squares Analysis; Lignans; Olive Oil; Phenylethyl Alcohol; Principal Component Analysis; Pyrans | 2018 |
Simple and efficient sustainable semi-synthesis of oleacein [2-(3,4-hydroxyphenyl) ethyl (3S,4E)-4-formyl-3-(2-oxoethyl)hex-4-enoate] as potential additive for edible oils.
Topics: Aldehydes; Food Additives; Humans; Iridoid Glucosides; Iridoids; Phenols; Phenylethyl Alcohol; Plant Oils | 2018 |
Protective Effects of Olive Leaf Extract on Acrolein-Exacerbated Myocardial Infarction via an Endoplasmic Reticulum Stress Pathway.
Topics: Acrolein; Animals; Apoptosis; Biological Products; Biomarkers; Cell Line; Cytoprotection; Disease Progression; Endoplasmic Reticulum Stress; Iridoid Glucosides; Iridoids; Isoproterenol; Male; Myocardial Infarction; Myocytes, Cardiac; Particulate Matter; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley | 2018 |
Efficient bioconversion of oleuropein from olive leaf extract to antioxidant hydroxytyrosol by enzymatic hydrolysis and high-temperature degradation.
Topics: Antioxidants; Enzymes; Esters; Hot Temperature; Hydrolysis; Iridoid Glucosides; Iridoids; Olea; Phenylethyl Alcohol; Plant Extracts; Plant Leaves | 2018 |
Improving in vivo conversion of oleuropein into hydroxytyrosol by oral granules containing probiotic Lactobacillus plantarum 299v and an Olea europaea standardized extract.
Topics: Administration, Oral; Animals; Bile; Drug Carriers; Drug Liberation; Feces; Gastric Juice; Iridoid Glucosides; Iridoids; Lactobacillus plantarum; Male; Mice; Olea; Phenylethyl Alcohol; Plant Extracts; Plant Leaves; Probiotics | 2018 |
Oleuropein and hydroxytyrosol protect rats' pups against bisphenol A induced hypothyroidism.
Topics: Animals; Animals, Suckling; Benzhydryl Compounds; Endocrine Disruptors; Female; Hypothyroidism; Iridoid Glucosides; Iridoids; Lactation; Olea; Phenols; Phenylethyl Alcohol; Plant Leaves; Protective Agents; Rats; Thyroid Hormones | 2018 |
Expression of hydroxytyrosol and oleuropein biosynthetic genes are correlated with metabolite accumulation during fruit development in olive, Olea europaea, cv. Koroneiki.
Topics: Fruit; Gene Expression Regulation, Plant; Genes, Plant; Iridoid Glucosides; Iridoids; Olea; Phenylethyl Alcohol | 2018 |
Oleuropein and hydroxytyrosol rich extracts from olive leaves attenuate liver injury and lipid metabolism disturbance in bisphenol A-treated rats.
Topics: Animals; Antioxidants; Benzhydryl Compounds; Humans; Iridoid Glucosides; Iridoids; Lipid Metabolism; Liver Diseases; Male; Olea; Phenols; Phenylethyl Alcohol; Plant Extracts; Plant Leaves; Rats | 2018 |
Olive leaf extract counteracts epithelial to mesenchymal transition process induced by peritoneal dialysis, through the inhibition of TGFβ1 signaling.
Topics: Antigens, Differentiation; Cadherins; Cell Line; Cell Membrane; Epithelial-Mesenchymal Transition; Glucosides; Humans; Iridoid Glucosides; Iridoids; Olea; Peritoneal Dialysis; Phenols; Phenylethyl Alcohol; Plant Extracts; Signal Transduction; Smad Proteins, Receptor-Regulated; Transforming Growth Factor beta1 | 2019 |
The Olive Biophenols Oleuropein and Hydroxytyrosol Selectively Reduce Proliferation, Influence the Cell Cycle, and Induce Apoptosis in Pancreatic Cancer Cells.
Topics: Apoptosis; Apoptosis Regulatory Proteins; Cell Cycle; Cell Line, Tumor; Humans; Iridoid Glucosides; Iridoids; Neoplasm Proteins; Olea; Pancreatic Neoplasms; Phenylethyl Alcohol | 2018 |
Structure-antioxidant activity relationship of β-cyclodextrin inclusion complexes with olive tyrosol, hydroxytyrosol and oleuropein: Deep insights from X-ray analysis, DFT calculation and DPPH assay.
Topics: beta-Cyclodextrins; Crystallography, X-Ray; Free Radical Scavengers; Hydrogen Bonding; Iridoid Glucosides; Iridoids; Models, Chemical; Molecular Structure; Phenylethyl Alcohol; Quantum Theory; Structure-Activity Relationship; Thermodynamics | 2018 |
Insecticidal effects of the Olea europaea subsp. laperrinei extracts on the flour Pyralid Ephestia kuehniella.
Topics: Animals; Chromatography, High Pressure Liquid; Female; Hesperidin; Insecticides; Iridoid Glucosides; Iridoids; Larva; Moths; Olea; Phenylethyl Alcohol; Plant Extracts; Plant Leaves; Quercetin | 2018 |
Antitumor Perspectives of Oleuropein.
Topics: Iridoid Glucosides; Iridoids; Phenylethyl Alcohol | 2019 |
Monitoring of acrylamide and phenolic compounds in table olive after high hydrostatic pressure and cooking treatments.
Topics: Acrylamide; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Cooking; Hydrostatic Pressure; Iridoid Glucosides; Iridoids; Olea; Olive Oil; Phenols; Phenylethyl Alcohol; Tandem Mass Spectrometry | 2019 |
Root verbascoside and oleuropein are potential indicators of drought resistance in olive trees (Olea europaea L.).
Topics: Antioxidants; Apigenin; Droughts; Flavonoids; Glucosides; Iridoid Glucosides; Iridoids; Olea; Phenol; Phenols; Phenylethyl Alcohol; Plant Extracts; Plant Leaves; Plant Roots; Polyphenols; Spectrophotometry, Ultraviolet; Stress, Physiological; Water | 2019 |
Continuous Bioconversion of Oleuropein from Olive Leaf Extract to Produce the Bioactive Product Hydroxytyrosol Using Carrier-Immobilized Enzyme.
Topics: Alginates; Biomass; Bioreactors; Cellulase; Ceramics; Chitosan; Enzymes, Immobilized; Hydrolysis; Iridoid Glucosides; Iridoids; Microscopy, Electron, Scanning; Olea; Phenylethyl Alcohol; Plant Leaves; Substrate Specificity; Thermogravimetry | 2020 |
Hydroxytyrosol and Oleuropein Inhibit Migration and Invasion of MDA-MB-231 Triple-Negative Breast Cancer Cell via Induction of Autophagy.
Topics: Antineoplastic Agents; Autophagy; Autophagy-Related Proteins; Cell Line, Tumor; Cell Movement; Cell Survival; Gene Expression; Humans; Iridoid Glucosides; Iridoids; Neoplasm Invasiveness; Phenylethyl Alcohol; Triple Negative Breast Neoplasms | 2019 |
Identification of putative genes for polyphenol biosynthesis in olive fruits and leaves using full-length transcriptome sequencing.
Topics: Alternative Splicing; Biosynthetic Pathways; Flavonoids; Fruit; Gene Expression Regulation, Plant; Iridoid Glucosides; Iridoids; Olea; Phenylethyl Alcohol; Plant Leaves; Polyphenols; Sequence Analysis, DNA; Transcriptome | 2019 |
Analysis of chemical composition in Chinese olive leaf tea by UHPLC-DAD-Q-TOF-MS/MS and GC-MS and its lipid-lowering effects on the obese mice induced by high-fat diet.
Topics: Animals; Beverages; Chromatography, Liquid; Diet, High-Fat; Gas Chromatography-Mass Spectrometry; Hyperlipidemias; Iridoid Glucosides; Iridoids; Male; Mice; Mice, Inbred ICR; Obesity; Olea; Phenylethyl Alcohol; Plant Leaves; Tandem Mass Spectrometry | 2020 |
Comparative Study on Beneficial Effects of Hydroxytyrosol- and Oleuropein-Rich Olive Leaf Extracts on High-Fat Diet-Induced Lipid Metabolism Disturbance and Liver Injury in Rats.
Topics: Animals; Dietary Fats; Iridoid Glucosides; Iridoids; Lipid Metabolism; Liver; Liver Diseases; Male; Olea; Phenylethyl Alcohol; Plant Extracts; Plant Leaves; Rats | 2020 |
Hydroxytyrosol and Oleuropein Inhibit Migration and Invasion via Induction of Autophagy in ER-Positive Breast Cancer Cell Lines (MCF7 and T47D).
Topics: Autophagy; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Female; Humans; Iridoid Glucosides; MCF-7 Cells; Phenylethyl Alcohol | 2021 |
Inhibition of human islet amyloid polypeptide aggregation and cellular toxicity by oleuropein and derivatives from olive oil.
Topics: Acetates; Cell Survival; Cyclopentane Monoterpenes; Diabetes Mellitus, Type 2; Diet, Mediterranean; Fluorescence; Humans; Inhibitory Concentration 50; Iridoid Glucosides; Iridoids; Islet Amyloid Polypeptide; Islets of Langerhans; Microscopy, Atomic Force; Olive Oil; Phenylethyl Alcohol; Phospholipids; Pyrans; Structure-Activity Relationship | 2020 |
Use of olive (Olea europaea L.) leaves as beer ingredient, and their influence on beer chemical composition and antioxidant activity.
Topics: Antioxidants; Beer; Female; Food Handling; Humans; Humulus; Iridoid Glucosides; Iridoids; Male; Olea; Phenols; Phenylethyl Alcohol; Plant Extracts; Plant Leaves; Polyphenols; Taste | 2020 |
Protective effects of olive oil phenolics oleuropein and hydroxytyrosol against hydrogen peroxide-induced DNA damage in human peripheral lymphocytes.
Topics: Antioxidants; DNA Damage; Dose-Response Relationship, Drug; Free Radical Scavengers; Humans; Hydrogen Peroxide; Iridoid Glucosides; Iridoids; Lymphocytes; Olive Oil; Phenylethyl Alcohol | 2021 |
A Quantitative Phytochemical Comparison of Olive Leaf Extracts on the Australian Market.
Topics: Antioxidants; Iridoid Glucosides; Iridoids; Olea; Phenylethyl Alcohol; Phytochemicals; Plant Extracts; Plant Leaves; Plants, Medicinal; Polyphenols | 2020 |
Target and Suspect HRMS Metabolomics for the Determination of Functional Ingredients in 13 Varieties of Olive Leaves and Drupes from Greece.
Topics: Chromatography, High Pressure Liquid; Geography; Greece; Hot Temperature; Iridoid Glucosides; Iridoids; Limit of Detection; Metabolomics; Olea; Phenylethyl Alcohol; Plant Extracts; Plant Leaves; Reproducibility of Results; Seasons; Seeds; Tandem Mass Spectrometry; Time Factors | 2020 |
Gender differences in the antioxidant response of oral administration of hydroxytyrosol and oleuropein against N-ethyl-N-nitrosourea (ENU)-induced glioma.
Topics: Administration, Oral; Animals; Antioxidants; Ethylnitrosourea; Glioma; Iridoid Glucosides; Phenylethyl Alcohol; Rats; Sex Characteristics | 2021 |
Olive polyphenols attenuate TNF-α-stimulated M-CSF and IL-6 synthesis in osteoblasts: Suppression of Akt and p44/p42 MAP kinase signaling pathways.
Topics: 3T3 Cells; Animals; Culture Media, Conditioned; Interleukin-6; Iridoid Glucosides; Macrophage Colony-Stimulating Factor; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinase 1; Olea; Oncogene Protein v-akt; Phenylethyl Alcohol; Polyphenols; Rotenone; Signal Transduction; Tumor Necrosis Factor-alpha | 2021 |
Dietary polyphenol oleuropein and its metabolite hydroxytyrosol are moderate skin permeable elastase and collagenase inhibitors with synergistic cellular antioxidant effects in human skin fibroblasts.
Topics: Antioxidants; Fibroblasts; Humans; Hydrogen Peroxide; Iridoid Glucosides; Iridoids; Matrix Metalloproteinase Inhibitors; Pancreatic Elastase; Phenylethyl Alcohol; Polyphenols; Reactive Oxygen Species | 2022 |
A new secoiridoid glucoside from
Topics: Esters; Glucosides; Iridoid Glucosides; Iridoids; Molecular Structure; Olea | 2022 |
Metabolomic and Transcriptional Profiling of Oleuropein Bioconversion into Hydroxytyrosol during Table Olive Fermentation by
Topics: Fermentation; Iridoid Glucosides; Olea; Phenylethyl Alcohol | 2022 |
Development and physicochemical characterization of nanoliposomes with incorporated oleocanthal, oleacein, oleuropein and hydroxytyrosol.
Topics: Aldehydes; Cyclopentane Monoterpenes; Humans; Iridoid Glucosides; Olea; Phenols; Phenylethyl Alcohol | 2022 |
A Bi-enzymatic Immobilized Nanobiocatalyst for the Biotransformation of Oleuropein to Hydroxytyrosol.
Topics: Biotransformation; Candida; Enzymes, Immobilized; Iridoid Glucosides; Phenylethyl Alcohol | 2022 |
Effect of heat treatment on phenolic composition and radical scavenging activity of olive leaf extract at different pH conditions: a spectroscopic and kinetic study.
Topics: Antioxidants; Hot Temperature; Hydrogen-Ion Concentration; Iridoids; Olea; Phenols; Plant Extracts; Plant Leaves | 2023 |
NOTCH1: A Novel Player in the Molecular Crosstalk Underlying Articular Chondrocyte Protection by Oleuropein and Hydroxytyrosol.
Topics: Cartilage, Articular; Cells, Cultured; Chondrocytes; Humans; Lipopolysaccharides; Osteoarthritis; Receptor, Notch1 | 2023 |
Comparative study of the effect of oleuropein and hydroxytyrosol rich extracts on the reproductive toxicity induced by bisphenol A in male rats: biochemical, histopathological, and molecular analyses.
Topics: Animals; bcl-2-Associated X Protein; Iridoids; Male; Plant Extracts; Rats; Rats, Wistar; Tumor Suppressor Protein p53 | 2023 |
Anti-Inflammatory Effects of Nutritionally Relevant Concentrations of Oleuropein and Hydroxytyrosol on Peripheral Blood Mononuclear Cells: An Age-Related Analysis.
Topics: Adolescent; Adult; Aged; Humans; Leukocytes, Mononuclear; Lipopolysaccharides; Middle Aged; Phenylethyl Alcohol; Polyphenols; Young Adult | 2023 |