Compounds > 3,4-dihydroxyphenylacetic acid

3,4-dihydroxyphenylacetic acid and selegiline

3,4-dihydroxyphenylacetic acid has been researched along with selegiline in 61 studies

Research

Studies (61)

Timeframe	Studies, this research(%)	All Research%
pre-1990	16 (26.23)	18.7374
1990's	33 (54.10)	18.2507
2000's	12 (19.67)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Kaakkola, S; Wurtman, RJ	1
Kuczenski, R; Okuda, C; Segal, DS	1
Greenshaw, AJ; Juorio, AV; Paterson, IA; Zhu, MY	1
Chan, WW; Rausch, WD; Riederer, P; Schallauer, E; Weiser, M	1
Kumagae, Y; Matsui, Y	1
Dluzen, DE; McDermott, JL	1
Cedarbaum, JM; Clark, M; Harts, A; Kutt, H; Silvestri, M	1
Garrett, MC; Soares-da-Silva, P	1
Bradbury, AJ; Costall, B; Jenner, PG; Kelly, ME; Marsden, CD; Naylor, RJ	1
Arai, Y; Kinemuchi, H; Kisara, K; Matsumura, T; Sakuma, I; Satoh, N; Tadano, T	1
Kaarttinen, A; Kallio, J; Koulu, M; Pyykkö, K; Scheinin, M; Vuorinen, J; Zimmer, RH	1
Greenshaw, AJ; Juorio, AV; Nguyen, TV	1
Hashim, A; Lajtha, A; Sershen, H; Wiener, HL	2
Goldstein, DS; Hovevey-Sion, D; Kopin, IJ; Stull, RW	1
Bizière, K; Guillaumin, JM; Kan, JP; Renoux, G; Renoux, M; Steinberg, R	1
Fuller, RW; Hemrick-Luecke, SK	1
Bretton, C; Hof, P; Ofori, S; Schorderet, M	1
Duvoisin, RC; Heikkila, RE; Nicklas, WJ	1
Duvoisin, RC; Heikkila, RE; Hess, A	1
Bocchetta, A; Corsini, GU; Del Zompo, M; Piccardi, MP; Pintus, S	1
Baraczka, K; Fekete, MI; Kanyicska, B	1
Hársing, LG; Vizi, ES	1
Calne, DB; Chuang, LW; Eisler, T; Karoum, F; Klein, DF; Liebowitz, MR; Quitkin, FM; Wyatt, RJ	1
Holdup, D; Liptrot, J; Phillipson, O	1
Gupta, M; Wiener, HL	1
Bankiewicz, KS; Finberg, JP; Goldstein, DS; Kopin, IJ; Wang, J	1
Sivam, SP	1
Corsini, GU; Fascetti, F; Fornai, F; Maggio, R; Vaglini, F	1
Juorio, AV; Paterson, IA; Zhu, MY	1
Bennett, JP; Parker, WD; Smith, TS	1
Abercrombie, ED; Wachtel, SR	1
Boulton, AA; Durden, DA; Dyck, LE	1
Ahlskog, JE; Low, PA; Nickander, KK; O'Brien, JF; Tyce, GM; Uitti, RJ	1
Boulton, AA; Davis, BA; Durden, DA; Ivy, G; Juorio, AV; Mendonca, A; Milgram, W; Paterson, IA; Wu, P; Yu, PH	1
Burger, R; Dirr, A; Götz, ME; Rausch, WD; Riederer, P	1
Finberg, JP; Lamensdorf, I; Youdim, MB	1
Dingemanse, J; Kettler, R; Kneer, J; Korn, A; Koulu, M; Wallnöfer, A; Zürcher, G	1
Chalmers-Redman, RM; Ju, WY; Tatton, NA; Tatton, WG; Wadia, JS	1
Cano, J; Machado, A; Rodríguez-Gómez, JA; Romero-Ramos, M; Venero, JL	1
Brannan, T; Martínez-Tica, J; Prikhojan, A; Yahr, MD	1
Dhingra, NK; Lakshmana, MK; Meti, BL; Raju, TR; Rao, BS; Ravikumar, R; Sudha, S	1
Iwata, S; Kaseda, S; Nomoto, M	1
Finberg, JP; Lamensdorf, I; Porat, S; Simantov, R	1
Guan, HJ; Ji, XQ; Wang, RG; Wu, WR; Zhu, XZ	1
Quadri, SK; ThyagaRajan, S	1
Mertz, K; Morgan, JI; Schmidt, J	1
Castagnoli, K; Castagnoli, N; Palmer, S	1
Gentsch, C; Spooren, WP; Waldmeier, P	1
Croll, RP; Pani, AK	1
Finberg, JP; Ilani, T; Lamensdorf, I	1
Felten, DL; Madden, KS; Stevens, SY; ThyagaRajan, S	1
MohanKumar, PS; MohanKumar, SM; Quadri, SK	1
Adachi, YU; Higuchi, H; Satoh, T; Vizi, ES; Watanabe, K	1
Barja, G; Fabre, E; Gredilla, R; Leret, ML; San Millán, JA	1
Fisher, H; Halladay, AK; Hesse, K; Kirschner, E; Wagner, GC	1
Fujimaru, S; Matsubara, K; Ohtaki, K; Saito, O; Shimizu, K; Shiono, H	1
Antkiewicz-Michaluk, L; Herman, ZS; Obuchowicz, E; Romańska, I	1
Adachi, K; Kondo, T; Kusumoto, H; Miwa, H; Shimazu, S	1
Chen, Q; Davidson, C; Ellinwood, EH; Lazarus, C; Lee, TH; Xiong, X; Zhang, X	1
Choudhury, ME; Kubo, M; Nagai, M; Nishikawa, N; Nomoto, M; Yabe, H	1

Reviews

1 review(s) available for 3,4-dihydroxyphenylacetic acid and selegiline

Article	Year
(-)-Deprenyl reduces neuronal apoptosis and facilitates neuronal outgrowth by altering protein synthesis without inhibiting monoamine oxidase. Journal of neural transmission. Supplementum, 1996, Volume: 48 Topics: 3,4-Dihydroxyphenylacetic Acid; Alzheimer Disease; Animals; Apoptosis; Cells, Cultured; Gene Expression Regulation; Humans; Mitochondria; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Nerve Degeneration; Nerve Tissue Proteins; Neurites; Neuroglia; Neurons; Neuroprotective Agents; Nootropic Agents; Oxidative Stress; Parkinson Disease; Protein Synthesis Inhibitors; Rats; Selegiline	1996

Article

Year

(-)-Deprenyl reduces neuronal apoptosis and facilitates neuronal outgrowth by altering protein synthesis without inhibiting monoamine oxidase.

Journal of neural transmission. Supplementum, 1996, Volume: 48

Topics: 3,4-Dihydroxyphenylacetic Acid; Alzheimer Disease; Animals; Apoptosis; Cells, Cultured; Gene Expression Regulation; Humans; Mitochondria; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Nerve Degeneration; Nerve Tissue Proteins; Neurites; Neuroglia; Neurons; Neuroprotective Agents; Nootropic Agents; Oxidative Stress; Parkinson Disease; Protein Synthesis Inhibitors; Rats; Selegiline

1996

Trials

2 trial(s) available for 3,4-dihydroxyphenylacetic acid and selegiline

Article	Year
Inhibition of monoamine oxidase by moclobemide: effects on monoamine metabolism and secretion of anterior pituitary hormones and cortisol in healthy volunteers. British journal of clinical pharmacology, 1989, Volume: 27, Issue:2 Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Benzamides; Blood Platelets; Catecholamines; Dose-Response Relationship, Drug; Double-Blind Method; Epinephrine; Homovanillic Acid; Humans; Hydrocortisone; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Moclobemide; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Norepinephrine; Pituitary Hormones, Anterior; Random Allocation; Selegiline; Vanilmandelic Acid	1989
Pharmacokinetic-pharmacodynamic interactions between two selective monoamine oxidase inhibitors: moclobemide and selegiline. Clinical neuropharmacology, 1996, Volume: 19, Issue:5 Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Benzamides; Blood Platelets; Double-Blind Method; Drug Interactions; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Moclobemide; Monoamine Oxidase Inhibitors; Neurotransmitter Agents; Selegiline	1996

Article

Year

Inhibition of monoamine oxidase by moclobemide: effects on monoamine metabolism and secretion of anterior pituitary hormones and cortisol in healthy volunteers.

British journal of clinical pharmacology, 1989, Volume: 27, Issue:2

Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Benzamides; Blood Platelets; Catecholamines; Dose-Response Relationship, Drug; Double-Blind Method; Epinephrine; Homovanillic Acid; Humans; Hydrocortisone; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Moclobemide; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Norepinephrine; Pituitary Hormones, Anterior; Random Allocation; Selegiline; Vanilmandelic Acid

1989

Pharmacokinetic-pharmacodynamic interactions between two selective monoamine oxidase inhibitors: moclobemide and selegiline.

Clinical neuropharmacology, 1996, Volume: 19, Issue:5

Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Benzamides; Blood Platelets; Double-Blind Method; Drug Interactions; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Moclobemide; Monoamine Oxidase Inhibitors; Neurotransmitter Agents; Selegiline

1996

Other Studies

58 other study(ies) available for 3,4-dihydroxyphenylacetic acid and selegiline

Article	Year
Effects of COMT inhibitors on striatal dopamine metabolism: a microdialysis study. Brain research, 1992, Aug-07, Volume: 587, Issue:2 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benzophenones; Catechol O-Methyltransferase Inhibitors; Catechols; Chromatography, High Pressure Liquid; Clorgyline; Corpus Striatum; Dialysis; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Nitriles; Nitrophenols; Nomifensine; Rats; Rats, Inbred Strains; Selegiline; Tolcapone	1992
Deprenyl alters behavior and caudate dopamine through an amphetamine-like action. Pharmacology, biochemistry, and behavior, 1992, Volume: 43, Issue:4 Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Behavior, Animal; Caudate Nucleus; Clorgyline; Dopamine; Dose-Response Relationship, Drug; Homovanillic Acid; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Selegiline	1992
The effects of some neuroleptics and d-amphetamine on striatal 2-phenylethylamine in the mouse. General pharmacology, 1991, Volume: 22, Issue:2 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antipsychotic Agents; Chlorpromazine; Corpus Striatum; Dextroamphetamine; Dopamine; Fluphenazine; Homovanillic Acid; In Vitro Techniques; Male; Mice; Monoamine Oxidase Inhibitors; Pargyline; Phenethylamines; Selegiline; Spiperone; Synaptic Transmission	1991
Effects of L-deprenyl and amantadine in an MPTP-model of parkinsonism. Journal of neural transmission. Supplementum, 1990, Volume: 32 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Amantadine; Animals; Caudate Nucleus; Corpus Striatum; Dopamine; Drug Interactions; Female; Gerbillinae; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Parkinson Disease, Secondary; Selegiline; Serotonin	1990
Monoamine oxidase inhibitors prevent striatal neuronal necrosis induced by transient forebrain ischemia. Neuroscience letters, 1991, May-27, Volume: 126, Issue:2 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Clorgyline; Corpus Striatum; Dopamine; Ischemic Attack, Transient; Isoenzymes; Male; Monoamine Oxidase Inhibitors; Necrosis; Neurons; Nitriles; Pyrimidines; Rats; Rats, Inbred Strains; Reperfusion; Selegiline	1991
The effect of long-term treatment with deprenyl on basal and L-dopa evoked dopamine release in vitro from the corpus striatum of aged rats. Journal of neural transmission. General section, 1991, Volume: 85, Issue:2 Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Amphetamine; Animals; Corpus Striatum; Dopamine; In Vitro Techniques; Levodopa; Male; Rats; Selegiline	1991
L-deprenyl, levodopa pharmacokinetics, and response fluctuations in Parkinson's disease. Clinical neuropharmacology, 1990, Volume: 13, Issue:1 Topics: 3,4-Dihydroxyphenylacetic Acid; Aged; Humans; Levodopa; Middle Aged; Parkinson Disease; Phenethylamines; Psychomotor Performance; Selegiline	1990
Role of type A and B monoamine oxidase on the formation of 3,4-dihydroxyphenylacetic acid (DOPAC) in tissues from the brain of the rat. Neuropharmacology, 1990, Volume: 29, Issue:10 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Cerebral Cortex; Clorgyline; Corpus Striatum; Dopamine; Homovanillic Acid; Isoenzymes; Male; Monoamine Oxidase; Nucleus Accumbens; Pargyline; Rats; Rats, Inbred Strains; Reference Values; Selegiline	1990
The neurotoxic actions of 1-methyl-4-phenylpyridine (MPP+) are not prevented by deprenyl treatment. Neuroscience letters, 1985, Jul-31, Volume: 58, Issue:2 Topics: 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Female; Homovanillic Acid; Hydroxyindoleacetic Acid; Limbic System; Mice; Motor Activity; Neurotransmitter Agents; Norepinephrine; Parkinson Disease, Secondary; Phenethylamines; Pyridinium Compounds; Selegiline; Serotonin	1985
Behavioral and biochemical changes following acute administration of MPTP and MPP+. Life sciences, 1987, Mar-30, Volume: 40, Issue:13 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Desipramine; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Mice; Motor Activity; Nomifensine; Pyridines; Pyridinium Compounds; Selegiline; Serotonin	1987
Lesion-induced reductions in trace amine accumulation: dependence on MAO inhibitor pretreatment. Brain research bulletin, 1989, Volume: 22, Issue:2 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Amines; Corpus Striatum; Dopamine; Homovanillic Acid; Hydroxydopamines; Male; Monoamine Oxidase Inhibitors; Oxidopamine; Pargyline; Rats; Rats, Inbred Strains; Selegiline; Substantia Nigra; Tryptamines	1989
Chronic L-deprenyl-induced up-regulation of the dopamine uptake carrier. European journal of pharmacology, 1989, Apr-12, Volume: 163, Issue:1 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Catecholamines; Corpus Striatum; Dopamine; Male; Mazindol; Mice; Mice, Inbred BALB C; Monoamine Oxidase; Phenethylamines; Receptors, Dopamine; Selegiline	1989
Chronic L-deprenyl does not alter the restoration of striatal dopamine in MPTP-lesioned mice. Journal of neuroscience research, 1989, Volume: 23, Issue:3 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Male; Mice; Mice, Inbred BALB C; Parkinson Disease, Secondary; Phenethylamines; Pyridines; Selegiline; Time Factors	1989
Effects of monoamine oxidase inhibitors on levels of catechols and homovanillic acid in striatum and plasma. Neuropharmacology, 1989, Volume: 28, Issue:8 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Catechols; Clorgyline; Corpus Striatum; Debrisoquin; Homovanillic Acid; Male; Methoxyhydroxyphenylglycol; Monoamine Oxidase Inhibitors; Nialamide; Norepinephrine; Rats; Rats, Inbred Strains; Selegiline	1989
Sodium diethyldithiocarbamate protects against the MPTP-induced inhibition of immune responses in mice. Life sciences, 1989, Volume: 44, Issue:12 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; B-Lymphocytes; Corpus Striatum; Designer Drugs; Ditiocarb; Dopamine; Homovanillic Acid; Immune System; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Male; Metallothionein 3; Mice; Mitogens; Pyridines; Selegiline; T-Lymphocytes	1989
A high dose of MPTP overcomes the protective effect of selegiline against dopaminergic neurotoxicity. The Journal of pharmacy and pharmacology, 1989, Volume: 41, Issue:7 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Homovanillic Acid; Male; Mice; Mice, Inbred Strains; Nervous System Diseases; Phenethylamines; Pyridines; Receptors, Dopamine; Selegiline	1989
Investigation of dopamine content, synthesis, and release in the rabbit retina in vitro: I. Effects of dopamine precursors, reserpine, amphetamine, and L-DOPA decarboxylase and monoamine oxidase inhibitors. Journal of neurochemistry, 1986, Volume: 47, Issue:4 Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Dopamine; Female; Levodopa; Male; Monoamine Oxidase Inhibitors; Pargyline; Rabbits; Reserpine; Retina; Selegiline; Tyrosine	1986
Studies on the mechanism of the dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Advances in neurology, 1987, Volume: 45 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Corpus Striatum; Dopamine; Homovanillic Acid; Male; Mice; Mice, Inbred Strains; Pyridines; Pyridinium Compounds; Receptors, Dopamine; Selegiline	1987
Dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP) in the mouse: relationships between monoamine oxidase, MPTP metabolism and neurotoxicity. Life sciences, 1985, Jan-21, Volume: 36, Issue:3 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Benzylamines; Clorgyline; Corpus Striatum; Dopamine; Homovanillic Acid; Male; Mice; Mice, Inbred C57BL; Monoamine Oxidase; Pyridines; Selegiline; Substantia Nigra; Synaptosomes; Tryptamines	1985
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine: correspondence of its binding sites to monoamine oxidase in rat brain, and inhibition of dopamine oxidative deamination in vivo and in vitro. Journal of neurochemistry, 1985, Volume: 45, Issue:3 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Binding Sites; Clorgyline; Corpus Striatum; Deamination; Dopamine; In Vitro Techniques; Male; Monoamine Oxidase; Oxidation-Reduction; Pargyline; Pyridines; Rats; Rats, Inbred Strains; Selegiline; Subcellular Fractions	1985
Changes in dopamine and 3,4-dihydroxyphenylacetic acid (DOPAC) levels in human cerebrospinal fluid after L-dopa and deprenyl administration. Journal of neural transmission, 1983, Volume: 58, Issue:3-4 Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Benserazide; Dopamine; Humans; Levodopa; Monoamine Oxidase; Phenethylamines; Phenylacetates; Selegiline	1983
Release of endogenous dopamine from rat isolated striatum: effect of clorgyline and (-)-deprenyl. British journal of pharmacology, 1984, Volume: 83, Issue:3 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Chromatography, High Pressure Liquid; Clorgyline; Corpus Striatum; Dopamine; In Vitro Techniques; Monoamine Oxidase; Phenethylamines; Propylamines; Rats; Rats, Inbred Strains; Selegiline; Time Factors	1984
Metabolism of (-) deprenyl to amphetamine and methamphetamine may be responsible for deprenyl's therapeutic benefit: a biochemical assessment. Neurology, 1982, Volume: 32, Issue:5 Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Amphetamines; Biogenic Amines; Carbidopa; Depression; Drug Combinations; Female; Humans; Levodopa; Male; Methamphetamine; Middle Aged; Monoamine Oxidase; Parkinson Disease; Phenethylamines; Selegiline; Tyramine	1982
1,2,3,4-Tetrahydro-2-methyl-4,6,7-isoquinolinetriol depletes catecholamines in rat brain. Journal of neurochemistry, 1993, Volume: 61, Issue:6 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Cerebral Ventricles; Clorgyline; Corpus Striatum; Dopamine; Functional Laterality; Homovanillic Acid; Hydroxyindoleacetic Acid; Hypothalamus; Infusions, Parenteral; Isoquinolines; Locus Coeruleus; Male; Microinjections; Norepinephrine; Organ Specificity; Raphe Nuclei; Rats; Rats, Wistar; Selegiline; Serotonin; Stereotaxic Techniques; Substantia Nigra; Thalamus	1993
Effects of deprenyl on monoamine oxidase and neurotransmitters in the brains of MPTP-treated aging mice. Neurochemical research, 1995, Volume: 20, Issue:4 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Brain; Corpus Striatum; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Mice; Mice, Inbred C57BL; Monoamine Oxidase; Neurotransmitter Agents; Olfactory Pathways; Selegiline	1995
Influence of selective inhibition of monoamine oxidase A or B on striatal metabolism of L-DOPA in hemiparkinsonian rats. Journal of neurochemistry, 1995, Volume: 65, Issue:3 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Clorgyline; Corpus Striatum; Dialysis; Dopamine; Homovanillic Acid; Indans; Levodopa; Male; Monoamine Oxidase Inhibitors; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Selegiline; Substantia Nigra	1995
Influence of monoamine oxidase inhibitors on striatonigral dynorphin system: a study with deprenyl and clorgyline. Neuropeptides, 1993, Volume: 25, Issue:1 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Clorgyline; Corpus Striatum; Dopamine; Dynorphins; Hydroxyindoleacetic Acid; Male; Monoamine Oxidase Inhibitors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Selegiline; Serotonin; Substantia Nigra	1993
(+)MK-801 prevents the DDC-induced enhancement of MPTP toxicity in mice. Brain research, 1994, Dec-30, Volume: 668, Issue:1-2 Topics: 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Animals; Ditiocarb; Dizocilpine Maleate; Dopamine; Drug Synergism; Haplorhini; Homovanillic Acid; Male; Mice; Mice, Inbred C57BL; MPTP Poisoning; Piperazines; Selegiline; Substantia Nigra; Tyrosine 3-Monooxygenase	1994
Dopamine metabolism in the guinea pig striatum: role of monoamine oxidase A and B. European journal of pharmacology, 1994, Mar-21, Volume: 254, Issue:3 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Guinea Pigs; Homovanillic Acid; Male; Monoamine Oxidase; Pargyline; Selegiline	1994
L-dopa increases nigral production of hydroxyl radicals in vivo: potential L-dopa toxicity? Neuroreport, 1994, Apr-14, Volume: 5, Issue:8 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Chromatography, High Pressure Liquid; Dopamine; Homovanillic Acid; Hydroxyl Radical; Levodopa; Microdialysis; Mitochondria; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Selegiline; Stereotaxic Techniques; Substantia Nigra	1994
L-3,4-dihydroxyphenylalanine-induced dopamine release in the striatum of intact and 6-hydroxydopamine-treated rats: differential effects of monoamine oxidase A and B inhibitors. Journal of neurochemistry, 1994, Volume: 63, Issue:1 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Clorgyline; Corpus Striatum; Dopamine; Levodopa; Male; Monoamine Oxidase Inhibitors; Nerve Endings; Oxidopamine; Picolinic Acids; Rats; Rats, Sprague-Dawley; Selegiline	1994
Effects of monoamine oxidase inhibitors on the acid metabolites of some trace amines and of dopamine in the rat striatum. Biochemical pharmacology, 1993, Mar-24, Volume: 45, Issue:6 Topics: 3,4-Dihydroxyphenylacetic Acid; Amines; Animals; Corpus Striatum; Dopamine; Male; Methyldopa; Monoamine Oxidase Inhibitors; Phenylacetates; Piperidines; Rats; Rats, Wistar; Selegiline	1993
Levodopa and deprenyl treatment effects on peripheral indices of oxidant stress in Parkinson's disease. Neurology, 1996, Volume: 46, Issue:3 Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Aged; Aged, 80 and over; Cysteinyldopa; Humans; Levodopa; Malondialdehyde; Methoxyhydroxyphenylglycol; Middle Aged; Oxidative Stress; Parkinson Disease; Selegiline	1996
Inhibition of MAO-B by (-)-deprenyl alters dopamine metabolism in the macaque (Macaca facicularis) brain. Neurochemical research, 1995, Volume: 20, Issue:12 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Caudate Nucleus; Dopamine; Frontal Lobe; Homovanillic Acid; Hydroxyindoleacetic Acid; Macaca fascicularis; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Phenethylamines; Selegiline; Serotonin	1995
High dose selegiline augments striatal ubiquinol in mouse: an indication of decreased oxidative stress or of interference with mitochondrial respiration? A pilot study. Journal of neural transmission. Supplementum, 1995, Volume: 46 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dose-Response Relationship, Drug; Homovanillic Acid; Male; Mice; Mice, Inbred C57BL; Mitochondria; Monoamine Oxidase Inhibitors; Oxidative Stress; Oxygen Consumption; Pilot Projects; Selegiline; Ubiquinone	1995
Effect of long-term treatment with selective monoamine oxidase A and B inhibitors on dopamine release from rat striatum in vivo. Journal of neurochemistry, 1996, Volume: 67, Issue:4 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Clorgyline; Corpus Striatum; Drug Administration Schedule; Homovanillic Acid; Indans; Isoenzymes; Male; Microdialysis; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Rats; Rats, Sprague-Dawley; Selegiline; Time Factors	1996
Chronic inhibition of the high-affinity dopamine uptake system increases oxidative damage to proteins in the aged rat substantia nigra. Free radical biology & medicine, 1997, Volume: 23, Issue:1 Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Blotting, Western; Dopamine; Dopamine Uptake Inhibitors; Free Radicals; Male; Nomifensine; Oxidative Stress; Proteins; Rats; Rats, Wistar; Selegiline; Substantia Nigra; Tyrosine 3-Monooxygenase	1997
In vivo comparison of the effects of inhibition of MAO-A versus MAO-B on striatal L-DOPA and dopamine metabolism. Journal of neural transmission. Parkinson's disease and dementia section, 1995, Volume: 10, Issue:2-3 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Clorgyline; Corpus Striatum; Dopamine; Homovanillic Acid; Levodopa; Male; Microdialysis; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Pargyline; Parkinson Disease; Rats; Rats, Sprague-Dawley; Selegiline	1995
Role of monoamine oxidase type A and B on the dopamine metabolism in discrete regions of the primate brain. Neurochemical research, 1998, Volume: 23, Issue:8 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Brain Chemistry; Clorgyline; Dopamine; Enzyme Activation; Homovanillic Acid; Injections, Intramuscular; Isoenzymes; Macaca radiata; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Organ Specificity; Selegiline	1998
Effect of selegiline on dopamine concentration in the striatum of a primate. Brain research, 1999, Jan-02, Volume: 815, Issue:1 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Callithrix; Corpus Striatum; Dopamine; Extracellular Space; Female; Homovanillic Acid; Male; Microdialysis; Monoamine Oxidase Inhibitors; Rats; Rats, Wistar; Selegiline	1999
Effect of low-dose treatment with selegiline on dopamine transporter (DAT) expression and amphetamine-induced dopamine release in vivo. British journal of pharmacology, 1999, Volume: 126, Issue:4 Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Carrier Proteins; Dopamine; Dopamine Plasma Membrane Transport Proteins; Male; Membrane Glycoproteins; Membrane Transport Proteins; Microdialysis; Monoamine Oxidase Inhibitors; Nerve Tissue Proteins; Rats; Rats, Sprague-Dawley; Selegiline	1999
Neuroprotective rather than neurorescue or neurorestorative effect of selegiline against MPTP-induced dopaminergic toxicity. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1999, Volume: 20, Issue:2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Corpus Striatum; Dopamine; Female; Mice; Mice, Inbred C57BL; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neuroprotective Agents; Random Allocation; Selegiline; Time Factors	1999
L-deprenyl inhibits tumor growth, reduces serum prolactin, and suppresses brain monoamine metabolism in rats with carcinogen-induced mammary tumors. Endocrine, 1999, Volume: 10, Issue:3 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Monoamines; Body Weight; Brain; Dopamine; Eating; Female; Homovanillic Acid; Hydroxyindoleacetic Acid; Mammary Neoplasms, Experimental; Monoamine Oxidase Inhibitors; Norepinephrine; Prolactin; Rats; Rats, Sprague-Dawley; Selegiline	1999
Regulation of heme oxygenase-1 expression by dopamine in cultured C6 glioma and primary astrocytes. Brain research. Molecular brain research, 1999, Nov-10, Volume: 73, Issue:1-2 Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcysteine; Animals; Ascorbic Acid; Astrocytes; Catechol O-Methyltransferase Inhibitors; Catechols; Cell Line; Cycloheximide; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Glioma; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Hemin; Membrane Proteins; Mice; Mice, Inbred C57BL; Monoamine Oxidase Inhibitors; RNA, Messenger; Selegiline; Time Factors; Tumor Cells, Cultured	1999
Neuroprotection by (R)-deprenyl and 7-nitroindazole in the MPTP C57BL/6 mouse model of neurotoxicity. Neurobiology (Budapest, Hungary), 1999, Volume: 7, Issue:2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Animals; Cattle; Corpus Striatum; Dopamine; Indazoles; Male; Mice; Mice, Inbred C57BL; Monoamine Oxidase; Neuroprotective Agents; Neurotoxins; Selegiline	1999
The effect of a subchronic post-lesion treatment with (-)-deprenyl on the sensitivity of 6-OHDA-lesioned rats to apomorphine and d-amphetamine. Journal of neural transmission (Vienna, Austria : 1996), 1999, Volume: 106, Issue:9-10 Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Amphetamine; Animals; Antiparkinson Agents; Apomorphine; Behavior, Animal; Corpus Striatum; Dopamine; Dopamine Agents; Homovanillic Acid; Male; Medial Forebrain Bundle; Oxidopamine; Rats; Rats, Sprague-Dawley; Selegiline	1999
Catechol concentrations in the hemolymph of the scallop, Placopecten magellanicus. General and comparative endocrinology, 2000, Volume: 118, Issue:1 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Catechol O-Methyltransferase Inhibitors; Catecholamines; Chromatography, High Pressure Liquid; Clorgyline; Dihydroxyphenylalanine; Dopamine; Female; Hemolymph; Male; Mollusca; Monoamine Oxidase Inhibitors; Pargyline; Selegiline; Sexual Behavior, Animal	2000
Selective monoamine oxidase subtype inhibition and striatal extracellular dopamine in the guinea-pig. British journal of pharmacology, 2000, Volume: 130, Issue:8 Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Catecholamines; Clorgyline; Corpus Striatum; Dialysis Solutions; Dihydroxyphenylalanine; Dopamine; Dopamine Uptake Inhibitors; Extracellular Space; Guinea Pigs; Homovanillic Acid; Isoenzymes; Male; Microdialysis; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Piperazines; Potassium Chloride; Rats; Selegiline; Synaptosomes; Tritium; Tyrosine 3-Monooxygenase	2000
Anti-tumor effect of L-deprenyl is associated with enhanced central and peripheral neurotransmission and immune reactivity in rats with carcinogen-induced mammary tumors. Journal of neuroimmunology, 2000, Sep-22, Volume: 109, Issue:2 Topics: 3,4-Dihydroxyphenylacetic Acid; 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Division; Female; Flow Cytometry; Hydroxyindoleacetic Acid; Immune System; Interferon-gamma; Interleukin-2; Killer Cells, Natural; Mammary Neoplasms, Experimental; Monoamine Oxidase Inhibitors; Neuroimmunomodulation; Norepinephrine; Rats; Rats, Sprague-Dawley; Selegiline; Serotonin; Spleen; Sympathetic Nervous System; Synaptic Transmission; T-Lymphocytes	2000
Deprenyl stimulates the efflux of monoamines from the rat hypothalamus in vitro. Brain research bulletin, 2001, Volume: 54, Issue:6 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Monoamines; Dopamine; Dose-Response Relationship, Drug; Hydroxyindoleacetic Acid; Hypothalamus; Male; Monoamine Oxidase Inhibitors; Neurons; Norepinephrine; Rats; Rats, Sprague-Dawley; Selegiline; Serotonin	2001
Oxygen inhalation enhances striatal dopamine metabolism and monoamineoxidase enzyme inhibition prevents it: a microdialysis study. European journal of pharmacology, 2001, Jun-22, Volume: 422, Issue:1-3 Topics: 3,4-Dihydroxyphenylacetic Acid; Administration, Inhalation; Animals; Clorgyline; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Homovanillic Acid; Hyperoxia; Male; Microdialysis; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Oxygen; Pargyline; Rats; Rats, Sprague-Dawley; Selegiline	2001
Deprenyl protects from MPTP-induced Parkinson-like syndrome and glutathione oxidation in rat striatum. Toxicology, 2002, Jan-25, Volume: 170, Issue:3 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Antiparkinson Agents; Behavior, Animal; Catecholamines; Dopamine; Dopamine Agents; Glutathione; Male; Neostriatum; Oxidation-Reduction; Parkinson Disease, Secondary; Rats; Rats, Wistar; Selegiline; Stereotaxic Techniques	2002
Role of monoamine oxidase inhibition and monoamine depletion in fenfluramine-induced neurotoxicity and serotonin release. Pharmacology & toxicology, 2001, Volume: 89, Issue:5 Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Methyltyrosine; Animals; Clorgyline; Corpus Striatum; Dopamine; Drug Interactions; Fenclonine; Fenfluramine; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Monoamine Oxidase Inhibitors; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Selegiline; Serotonin; Serotonin Antagonists; Tryptophan	2001
Paraquat induces long-lasting dopamine overflow through the excitotoxic pathway in the striatum of freely moving rats. Brain research, 2003, Jun-27, Volume: 976, Issue:2 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dizocilpine Maleate; Dopamine; Dopamine Plasma Membrane Transport Proteins; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Extracellular Space; Glutamic Acid; Herbicides; Homovanillic Acid; Male; Membrane Glycoproteins; Membrane Transport Proteins; Motor Activity; Nerve Tissue Proteins; Neuroprotective Agents; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Paraquat; Parkinsonian Disorders; Quinoxalines; Rats; Rats, Wistar; Selegiline	2003
Increased striatal neuropeptide Y immunoreactivity and its modulation by deprenyl, clonidine and L-dopa in MPTP-treated mice. Journal of neural transmission (Vienna, Austria : 1996), 2003, Volume: 110, Issue:12 Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic alpha-Antagonists; Animals; Chromatography, High Pressure Liquid; Clonidine; Corpus Striatum; Dopamine; Homovanillic Acid; Immunohistochemistry; Levodopa; Male; Mice; MPTP Poisoning; Neuropeptide Y; Neuroprotective Agents; Selegiline; Serotonin	2003
Effects of subchronic treatment with selegiline on L-DOPA-induced increase in extracellular dopamine level in rat striatum. Journal of pharmacological sciences, 2006, Volume: 101, Issue:4 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Drug Administration Schedule; Extracellular Space; Homovanillic Acid; Injections, Intraperitoneal; Levodopa; Male; Microdialysis; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Rats; Rats, Sprague-Dawley; Selegiline; Time Factors	2006
Deprenyl treatment attenuates long-term pre- and post-synaptic changes evoked by chronic methamphetamine. European journal of pharmacology, 2007, Nov-14, Volume: 573, Issue:1-3 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antiparkinson Agents; Blotting, Western; Body Weight; Caudate Nucleus; Chromatography, High Pressure Liquid; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Immunochemistry; Infusion Pumps, Implantable; Injections, Subcutaneous; Male; Mesencephalon; Methamphetamine; Phosphorylation; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Selegiline; Substantia Nigra; Synapses; Time Factors; Tyrosine 3-Monooxygenase	2007
Zonisamide increases dopamine turnover in the striatum of mice and common marmosets treated with MPTP. Journal of pharmacological sciences, 2009, Volume: 110, Issue:1 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Anticonvulsants; Biogenic Amines; Brain Chemistry; Callithrix; Dopamine; Dopamine Agents; Dyskinesia, Drug-Induced; Homovanillic Acid; Isoxazoles; Male; Mice; Mice, Inbred C57BL; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neostriatum; Neurons; Selegiline; Zonisamide	2009