3,4-dihydroxyphenylacetic acid has been researched along with piperidines in 50 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (34.00) | 18.7374 |
| 1990's | 18 (36.00) | 18.2507 |
| 2000's | 8 (16.00) | 29.6817 |
| 2010's | 6 (12.00) | 24.3611 |
| 2020's | 1 (2.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nose, T; Takemoto, H | 1 |
| Waldmeier, PC | 3 |
| Annunziato, LA; Moore, KE; Wuerthele, SM | 1 |
| Bjerkenstedt, L; Skett, P; Wiesel, FA | 1 |
| Donnerer, J; Humpel, C; Saria, A | 1 |
| Fadayel, GM; Schmidt, CJ; Sullivan, CK; Taylor, VL | 1 |
| Katz, JL; Martello, AL; Martello, MB; Ricaurte, GA | 1 |
| Culp, S; DeSouza, EB; Lehmann, J; Zaczek, R | 1 |
| Carlsson, A; Kujacic, M; Löfberg, L; Svensson, K | 1 |
| Abbate, GM; Nieduzak, TR; Schmidt, CJ; Taylor, VL | 1 |
| Cler, JA; Contreras, PC; Dilworth, VM; Iyengar, S; Mick, SJ; Rao, TS; Wood, PL | 1 |
| Bøgesø, KP; Carlsson, A; Hyttel, J; Liljefors, T; Svensson, K; Wikström, H | 1 |
| Kim, HS; Lehmann, J; Martin, LL; Rao, TS; Wood, PL | 1 |
| Henning, K; Pindur, U; Przuntek, H; Russ, H | 1 |
| D'Angio, M; Scatton, B; Serrano, A | 1 |
| Da Prada, M; Keller, HH; Kettler, R | 1 |
| Jenner, P; Kelly, E; Marsden, CD | 2 |
| Di Chiara, G; Frau, R; Imperato, A; Tanda, G | 1 |
| Hedner, T; Lundborg, P | 1 |
| Bhaird, NN; Fowler, CJ; Thorberg, O; Tipton, KF | 1 |
| Bacopoulos, NG; Koch, SW; Koe, BK | 1 |
| Baumann, PA; Bernasconi, R; Buech, O; Delini-Stula, A; Felner, AE; Sigg, K; Waldmeier, PC | 1 |
| Feldtrauer, JJ; Paul, E; Stoecklin, K; Waldmeier, PC | 1 |
| Furukawa, H; Hasegawa, T; Kitaichi, K; Nabeshima, T; Yamada, K | 1 |
| Fadayel, GM; Schmidt, CJ | 1 |
| Matsunaga, KH; Matsuno, K; Mita, S | 1 |
| Misawa, M; Onodera, K; Suzuki, T; Takamori, K | 1 |
| Fadayel, GM; Schmidt, CJ; Sullivan, CK | 1 |
| Boulton, AA; Durden, DA; Dyck, LE | 1 |
| Carlsson, A; Carlsson, ML; Martin, P; Schmidt, CJ; Waters, N | 1 |
| Biggs, CS; Fisher, A; Starr, MS | 1 |
| Biggs, CS; Starr, MS | 1 |
| Double, K; Gerlach, M; Heinemann, T; Rausch, WD; Riederer, P; Xiao, AY | 1 |
| Bymaster, FP; Nomikos, GG; Perry, KW; Rodriguez, DE; Tzavara, ET | 1 |
| Allouard, N; Bert, L; Bougault, I; Le-Fur, G; Rodier, D; Soubrié, P; Steinberg, R | 1 |
| de Miguel, R; De Petrocellis, L; Di Marzo, V; Fernández-Ruiz, J; Lastres-Becker, I; Makriyannis, A | 1 |
| Cagnotto, A; De Deurwaerdère, P; Marrazzo, A; Mennini, T; Moison, D; Prezzavento, O; Ronsisvalle, G; Spampinato, U | 1 |
| Akhtar, S; Arif, M; Haleem, DJ; Mushtaq, N; Saify, ZS | 1 |
| de Souza Silva, MA; Huston, JP; Jocham, G; Kart-Teke, E; Lezoch, K; Müller, CP | 1 |
| Argiolas, A; Boi, A; Melis, MR; Melis, T; Sanna, F; Succu, S | 1 |
| Pettersson, F; Pontén, H; Sonesson, C; Waters, N; Waters, S | 1 |
| Pettersson, F; Sonesson, C; Svensson, P; Waters, N; Waters, S | 1 |
| Ahmed, A; Akhtar, S; Akram, A; Arif, M; Haleem, DJ; Mushtaq, N; Saify, ZS | 1 |
| Edling, M; Klamer, D; Ponten, H; Svanberg, B; Waters, N; Waters, S | 1 |
| Chatterjee, D; Facciol, A; Gerlai, R; Tran, S | 1 |
| Esteban, G; Marco-Contelles, J; Smolders, I; Sun, P; Unzeta, M; Van Eeckhaut, A; Van Schoors, J | 1 |
| Belliard, S; Berrebi-Bertrand, I; Finance, O; Giret, M; Krief, S; Lecomte, JM; Ligneau, X; Nagmar, I; Perrin, D; Robert, P; Schwartz, JC; Uguen, M | 1 |
50 other study(ies) available for 3,4-dihydroxyphenylacetic acid and piperidines
| Article | Year |
|---|---|
The effect of penfluridol and some psychotropic drugs on monoamine metabolism in central nervous system.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Amines; Brain; Brain Chemistry; Chlordiazepoxide; Chlorpromazine; Diazepam; Dopamine; Haloperidol; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Mice; Norepinephrine; Penfluridol; Pimozide; Piperazines; Piperidines; Psychotropic Drugs; Rats; Serotonin | 1975 |
Analysis of the activation of dopamine metabolism by a serotonin uptake inhibitor.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Baclofen; Benzofurans; Corpus Striatum; Dopamine; Female; Haloperidol; Homovanillic Acid; Piperidines; Rats; Scopolamine; Serotonin Antagonists; Time Factors | 1979 |
Comparative effects of penfluridol on circling behavior and striatal DOPAC and serum prolactin concentrations in the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Behavior; Corpus Striatum; Drug Interactions; Humans; Male; Penfluridol; Phenylacetates; Piperidines; Prolactin; Rats; Stereotyped Behavior; Time Factors | 1978 |
Effect of melperone, two of its metabolites and thiothixene on central monoamine metabolism and prolactin levels in rodents.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Butyrophenones; Catecholamines; Chemical Phenomena; Chemistry; Dose-Response Relationship, Drug; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Mice; Piperidines; Prolactin; Rats; Thiothixene; Time Factors | 1978 |
Effect of noradrenergic denervation by neonatal DSP-4 on peptide neurotransmitter systems in the rat brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benzylamines; Brain; Dopamine; Neuropeptides; Neurotoxins; Neurotransmitter Agents; Norepinephrine; Piperidines; Rats; Rats, Inbred Strains; Serotonin Antagonists; Sympathectomy, Chemical | 1992 |
5-HT2 receptors exert a state-dependent regulation of dopaminergic function: studies with MDL 100,907 and the amphetamine analogue, 3,4-methylenedioxymethamphetamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; 3,4-Methylenedioxyamphetamine; Animals; Brain Chemistry; Dialysis; Dopamine; Fluorobenzenes; Haloperidol; Homovanillic Acid; Male; N-Methyl-3,4-methylenedioxyamphetamine; Piperidines; Rats; Rats, Sprague-Dawley; Reserpine; Serotonin Antagonists | 1992 |
Lasting effects of (+-)-3,4-methylenedioxymethamphetamine (MDMA) on central serotonergic neurons in nonhuman primates: neurochemical observations.
Topics: 3,4-Dihydroxyphenylacetic Acid; 3,4-Methylenedioxyamphetamine; Animals; Brain; Cell Membrane; Chromatography, High Pressure Liquid; Dopamine; Female; Hydroxyindoleacetic Acid; Injections, Subcutaneous; Male; N-Methyl-3,4-methylenedioxyamphetamine; Neurons; Norepinephrine; Paroxetine; Piperidines; Saimiri; Serotonin; Serotonin Antagonists | 1992 |
Regional distribution to recovery of 5-HT levels after administration of "atrophins" MDMA and D,L-fenfluramine. Stereospecificity and comparison with 5,7-dihydroxytryptamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; 3,4-Methylenedioxyamphetamine; 5,7-Dihydroxytryptamine; Animals; Atrophy; Brain; Cerebral Ventricles; Designer Drugs; Dopamine; Fenfluramine; Homovanillic Acid; Hydroxyindoleacetic Acid; Injections, Intraventricular; Male; N-Methyl-3,4-methylenedioxyamphetamine; Norepinephrine; Organ Specificity; Paroxetine; Piperidines; Rats; Rats, Inbred Strains; Serotonin; Stereoisomerism | 1992 |
Dopamine receptors, controlling dopamine levels in rat adrenal glands-comparison with central dopaminergic autoreceptors.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenal Medulla; Animals; Apomorphine; Azepines; Diencephalon; Domperidone; Dopamine; Dopamine Agents; Epinephrine; Ergolines; Lisuride; Male; Norepinephrine; Phenanthrenes; Piperidines; Quinpirole; Rats; Rats, Inbred Strains; Receptors, Dopamine; Telencephalon | 1991 |
5-HT2 antagonists stereoselectively prevent the neurotoxicity of 3,4-methylenedioxymethamphetamine by blocking the acute stimulation of dopamine synthesis: reversal by L-dopa.
Topics: 3,4-Dihydroxyphenylacetic Acid; 3,4-Methylenedioxyamphetamine; Animals; Anti-Arrhythmia Agents; Brain; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Drug Synergism; Haloperidol; Homovanillic Acid; Levodopa; Male; Nomifensine; Piperidines; Rats; Rats, Inbred Strains; Ritanserin; Serotonin Antagonists; Stereoisomerism; Time Factors | 1991 |
Neurochemical characterization of dopaminergic effects of opipramol, a potent sigma receptor ligand, in vivo.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Corpus Striatum; Dopamine; Haloperidol; Homovanillic Acid; Ligands; Male; Mice; Opipramol; Organ Specificity; Phencyclidine; Piperidines; Quinolines; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Phencyclidine; Receptors, sigma | 1990 |
Pre- and postsynaptic dopaminergic activities of indolizidine and quinolizidine derivatives of 3-(3-hydroxyphenyl)-N-(n-propyl)piperidine (3-PPP). Further developments of a dopamine receptor model.
Topics: 3,4-Dihydroxyphenylacetic Acid; 5-Hydroxytryptophan; Animals; Dopamine Agents; Dopamine Antagonists; Male; Models, Structural; Molecular Conformation; Motor Activity; Piperidines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Structure-Activity Relationship | 1990 |
Selective activation of dopaminergic pathways in the mesocortex by compounds that act at the phencyclidine (PCP) binding site: tentative evidence for PCP recognition sites not coupled to N-methyl-D-aspartate (NMDA) receptors.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Carbazoles; Cerebral Cortex; Dibenzocycloheptenes; Dizocilpine Maleate; Dopamine; Dose-Response Relationship, Drug; Guanidines; Ligands; Male; Neural Pathways; Pipecolic Acids; Piperazines; Piperidines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, Phencyclidine; Stereoisomerism | 1990 |
The protective effect of 1-tert.butyl-4,4-diphenylpiperidine against the nigrostriatal neurodegeneration caused by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Dopamine; Drug Interactions; Female; Homovanillic Acid; Hydroxyindoleacetic Acid; Piperidines; Pyridines; Rats; Rats, Inbred Strains; Serotonin | 1985 |
NMDA antagonists block restraint-induced increase in extracellular DOPAC in rat nucleus accumbens.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic alpha-Antagonists; Animals; Aspartic Acid; Carbolines; Convulsants; Diazepam; Male; N-Methylaspartate; Nucleus Accumbens; Phenylacetates; Piperazines; Piperidines; Rats; Rats, Inbred Strains; Restraint, Physical; Riluzole; Septal Nuclei; Thiazoles | 1989 |
[Comparison of the new MAO-A inhibitors moclobemide, brofaromine and toloxatone with tranylcypromine in an animal experiment: significance for clinical practice].
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antidepressive Agents; Benzamides; Blood Pressure; Heart Rate; Moclobemide; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones; Piperidines; Rats; Serotonin; Structure-Activity Relationship; Tranylcypromine | 1989 |
Comparison of changes in locomotor activity with striatal homovanillic acid and 3,4-dihydroxyphenylacetic acid concentrations following the bilateral intranigral injection of dopamine agonist drugs in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Corpus Striatum; Dopamine; Female; Homovanillic Acid; Motor Activity; Phenylacetates; Piperidines; Rats; Rats, Inbred Strains; Substantia Nigra; Sucrose | 1987 |
Pharmacological profile of dopamine receptor agonists as studied by brain dialysis in behaving rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Azepines; Behavior, Animal; Benzazepines; Brain; Dialysis; Dopamine; Ergolines; Homovanillic Acid; Isomerism; Male; Motor Activity; Neurons; Pergolide; Piperidines; Quinpirole; Rats; Rats, Inbred Strains; Receptors, Dopamine; Time Factors | 1988 |
Development of dopamine autoreceptors in the postnatal rat brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Age Factors; Animals; Brain; Brain Chemistry; Dihydroxyphenylalanine; Motor Activity; Norepinephrine; Piperidines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Stereoisomerism | 1985 |
Lack of effect of intranigral administration of a dopamine analogue, (+/-)-3-(3-hydroxyphenyl)-N,n-propylpiperidine [(+/-)-3-PPP], on nigrostriatal dopamine neurones.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Corpus Striatum; Dopamine; Female; Homovanillic Acid; Motor Activity; Piperidines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Substantia Nigra | 1985 |
On the reversibility of reversible MAO inhibitors.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benzamides; Brain; Clorgyline; Dopamine; Female; Homovanillic Acid; Kinetics; Liver; Moclobemide; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones; Phenethylamines; Piperidines; Rats; Rats, Inbred Strains; Serotonin | 1985 |
Involvement of catechol-O-methyl transferase in the metabolism of the putative dopamine autoreceptor agonist 3-PPP(3-(3-hydroxyphenyl)-N-n-propylpiperidine).
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Catechol O-Methyltransferase; Cattle; Dopamine; Kinetics; Liver; Methylation; Piperidines; Pyrogallol | 1985 |
Differential effects of the enantiomers of 3-(3-hydroxyphenyl)-N-n-propylpiperidine (3-PPP) at dopamine receptor sites.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Corpus Striatum; Dopamine; Homovanillic Acid; Male; Mice; Molecular Conformation; Piperidines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Stereoisomerism; Synaptosomes; Tyrosine 3-Monooxygenase | 1983 |
Characterization of a new, short-acting and specific inhibitor of type A monoamine oxidase.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Amines; Brain; Brain Chemistry; Female; Hemodynamics; Hydroxyindoleacetic Acid; Liver; Male; Methoxyhydroxyphenylglycol; Monoamine Oxidase Inhibitors; Piperidines; Rats; Rats, Inbred Strains; Serotonin Antagonists; Synaptosomes; Tranylcypromine | 1983 |
Reversibility of the interaction of CGP 11305 A with MAO A in vivo.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Clorgyline; Dopamine; Female; Homovanillic Acid; Hydroxyindoleacetic Acid; Liver; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Piperidines; Rats; Serotonin; Tetrabenazine | 1983 |
Serotoninergic modulation of mesolimbic and frontal cortical dopamine neurons.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benzofurans; Cerebral Cortex; Corpus Striatum; Dopamine; Fenclonine; Haloperidol; Homovanillic Acid; Limbic System; Mianserin; Neurons; Organ Specificity; Piperidines; Rats; Serotonin | 1980 |
Effects of risperidone on phencyclidine-induced behaviors: comparison with haloperidol and ritanserin.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antipsychotic Agents; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Frontal Lobe; Haloperidol; Homovanillic Acid; Hydroxyindoleacetic Acid; Injections, Intraperitoneal; Isoxazoles; Locomotion; Male; Phencyclidine; Piperidines; Random Allocation; Rats; Rats, Wistar; Risperidone; Ritanserin; Schizophrenia; Serotonin; Stereotyped Behavior | 1994 |
The selective 5-HT2A receptor antagonist, MDL 100,907, increases dopamine efflux in the prefrontal cortex of the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Dopamine; Electrophysiology; Fluorobenzenes; Homovanillic Acid; In Vitro Techniques; Male; Microdialysis; Piperidines; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Ritanserin; Serotonin Antagonists | 1995 |
Acute effects of sigma ligands on the extracellular DOPAC level in rat frontal cortex and striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Anticonvulsants; Antipsychotic Agents; Carbazoles; Corpus Striatum; Extracellular Space; Frontal Lobe; Guanidines; Kinetics; Ligands; Male; Microdialysis; Pentazocine; Phenazocine; Piperidines; Rats; Rats, Wistar; Receptors, sigma; Time Factors | 1995 |
Effects of the histaminergic system on the morphine-induced conditioned place preference in mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benzazepines; Benzothiazoles; Conditioning, Operant; Dihydroxyphenylalanine; Dopamine; Dose-Response Relationship, Drug; Histamine; Histamine H2 Antagonists; Histidine; Histidine Decarboxylase; Homovanillic Acid; Limbic System; Male; Methylhistidines; Mice; Mice, Inbred Strains; Morphine; Phenoxypropanolamines; Piperidines; Prosencephalon; Thiazoles | 1995 |
Blockade of striatal 5-hydroxytryptamine2 receptors reduces the increase in extracellular concentrations of dopamine produced by the amphetamine analogue 3,4-methylenedioxymethamphetamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; 3,4-Methylenedioxyamphetamine; Animals; Corpus Striatum; Dialysis; Dopamine; Extracellular Space; Fluorobenzenes; Homovanillic Acid; Kinetics; N-Methyl-3,4-methylenedioxyamphetamine; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Antagonists; Tetrodotoxin | 1994 |
Effects of monoamine oxidase inhibitors on the acid metabolites of some trace amines and of dopamine in the rat striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amines; Animals; Corpus Striatum; Dopamine; Male; Methyldopa; Monoamine Oxidase Inhibitors; Phenylacetates; Piperidines; Rats; Rats, Wistar; Selegiline | 1993 |
Rodent data and general hypothesis: antipsychotic action exerted through 5-Ht2A receptor antagonism is dependent on increased serotonergic tone.
Topics: 3,4-Dihydroxyphenylacetic Acid; 5-Hydroxytryptophan; Animals; Antipsychotic Agents; Biogenic Monoamines; Brain; Dextroamphetamine; Dihydroxyphenylalanine; Dizocilpine Maleate; Dopamine; Fenclonine; Fluorobenzenes; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Mice; Mice, Inbred Strains; Models, Neurological; Motor Activity; Norepinephrine; Normetanephrine; Organ Specificity; Piperidines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Serotonin; Serotonin Antagonists | 1998 |
The antiparkinsonian drug budipine stimulates the activity of aromatic L-amino acid decarboxylase and enhances L-DOPA-induced dopamine release in rat substantia nigra.
Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Methyltyrosine; Animals; Antiparkinson Agents; Aromatic-L-Amino-Acid Decarboxylases; Corpus Striatum; Dopamine; Drug Synergism; Kinetics; Levodopa; Male; Microdialysis; Piperidines; Rats; Rats, Wistar; Reserpine; Substantia Nigra; Time Factors | 1998 |
Microdialysis study of the effects of the antiparkinsonian drug budipine on L-DOPA-induced release of dopamine and 5-hydroxytryptamine by rat substantia nigra and corpus striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Uptake Inhibitors; alpha-Methyltyrosine; Animals; Antiparkinson Agents; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Levodopa; Male; Microdialysis; Piperidines; Rats; Rats, Wistar; Reserpine; Serotonin; Substantia Nigra; Tyrosine 3-Monooxygenase | 1999 |
The industrial chemical Tinuvin 123 does not induce dopaminergic neurotoxicity in C57Bl/6 mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Decanoic Acids; Dopamine; Dose-Response Relationship, Drug; Homovanillic Acid; Injections, Subcutaneous; Male; Mice; Mice, Inbred C57BL; Neurons; Neurotransmitter Agents; Pharmaceutical Vehicles; Piperidines; Tyrosine 3-Monooxygenase | 2000 |
The cannabinoid CB(1) receptor antagonist SR141716A increases norepinephrine outflow in the rat anterior hypothalamus.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Dose-Response Relationship, Drug; Homovanillic Acid; Hydroxyindoleacetic Acid; Hypothalamus; Male; Microdialysis; Norepinephrine; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Serotonin | 2001 |
Permissive role of neurokinin NK(3) receptors in NK(1) receptor-mediated activation of the locus coeruleus revealed by SR 142801.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antiemetics; Dose-Response Relationship, Drug; Guinea Pigs; Locus Coeruleus; Male; Neural Pathways; Neurokinin-1 Receptor Antagonists; Neurons; Norepinephrine; Peptide Fragments; Piperidines; Prefrontal Cortex; Pyrrolidonecarboxylic Acid; Receptors, Neurokinin-1; Receptors, Neurokinin-3; Substance P; Tetrazoles | 2002 |
Compounds acting at the endocannabinoid and/or endovanilloid systems reduce hyperkinesia in a rat model of Huntington's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amino Acids, Neutral; Animals; Arachidonic Acids; Basal Ganglia; Cannabinoid Receptor Modulators; Capsaicin; Corpus Striatum; Cyclohexanols; Disease Models, Animal; Dopamine; Endocannabinoids; gamma-Aminobutyric Acid; Huntington Disease; Hyperkinesis; Male; Motor Activity; Nitro Compounds; Palmitates; Piperidines; Propionates; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptors, Cannabinoid; Receptors, Drug; Rimonabant | 2003 |
Intrastriatal administration of sigma ligands inhibits basal dopamine release in vivo.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Cyclopropanes; Dopamine; Dopamine Antagonists; Guanidines; Guinea Pigs; Haloperidol; In Vitro Techniques; Male; Microinjections; Neostriatum; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, sigma | 2003 |
Neurochemical estimations of some new quaternary phenacyl-bromopiperidinium compounds.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Brain Chemistry; Chromatography, High Pressure Liquid; Dopamine; Dopamine Antagonists; Homovanillic Acid; Hydroxyindoleacetic Acid; Injections, Intraperitoneal; Male; Mice; Piperidines; Serotonin | 2005 |
Neurokinin receptor antagonism attenuates cocaine's behavioural activating effects yet potentiates its dopamine-enhancing action in the nucleus accumbens core.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Antipsychotic Agents; Behavior, Animal; Cocaine; Conditioning, Operant; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Extracellular Fluid; Homovanillic Acid; Locomotion; Male; Microdialysis; Nucleus Accumbens; Piperidines; Rats; Rats, Wistar; Receptors, Neurokinin-3 | 2006 |
The cannabinoid antagonist SR 141716A (Rimonabant) reduces the increase of extra-cellular dopamine release in the rat nucleus accumbens induced by a novel high palatable food.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Appetite Regulation; Dopamine; Eating; Extracellular Fluid; Male; Microdialysis; Nucleus Accumbens; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Rimonabant | 2007 |
Synthesis and evaluation of a set of 4-phenylpiperidines and 4-phenylpiperazines as D2 receptor ligands and the discovery of the dopaminergic stabilizer 4-[3-(methylsulfonyl)phenyl]-1-propylpiperidine (huntexil, pridopidine, ACR16).
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Binding, Competitive; Cell Line; Corpus Striatum; Dopamine; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Drug Discovery; Drug Evaluation, Preclinical; Humans; Ligands; Male; Models, Chemical; Molecular Structure; Motor Activity; Piperazines; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2 | 2010 |
Synthesis and evaluation of a set of para-substituted 4-phenylpiperidines and 4-phenylpiperazines as monoamine oxidase (MAO) inhibitors.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benzene Derivatives; Catalytic Domain; Corpus Striatum; Dopamine; Humans; Isoenzymes; Models, Molecular; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Piperazines; Piperidines; Rats; Structure-Activity Relationship | 2012 |
Behavioral and neurochemical profile of some novel phenacyl based isonipecotamide derivatives.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amides; Animals; Antidepressive Agents; Behavior, Animal; Brain; Dopamine; Dose-Response Relationship, Drug; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Molecular Structure; Motor Activity; Piperidines; Rats; Rats, Wistar; Serotonin; Serotonin Antagonists; Structure-Activity Relationship | 2012 |
The dopaminergic stabilizers pridopidine and ordopidine enhance cortico-striatal Arc gene expression.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Apoptosis Regulatory Proteins; Cerebral Cortex; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Dopamine Agents; Electrochemical Techniques; Gene Expression Regulation; Male; Motor Activity; Muscle Proteins; Piperidines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Statistics as Topic | 2014 |
Concentration, population, and context-dependent effects of AM251 in zebrafish.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Anxiety; Brain; Dopamine; Dose-Response Relationship, Drug; Exploratory Behavior; Female; Hydroxyindoleacetic Acid; Locomotion; Male; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Serotonin; Species Specificity; Zebrafish | 2016 |
In-vitro and in-vivo evaluation of the modulatory effects of the multitarget compound ASS234 on the monoaminergic system.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alzheimer Disease; Animals; Biogenic Monoamines; Cell Line, Tumor; Dopamine; Hippocampus; Homovanillic Acid; Indoles; Ligands; Male; Monoamine Oxidase; Norepinephrine; PC12 Cells; Piperidines; Prefrontal Cortex; Rats; Rats, Wistar; Serotonin | 2017 |
Pitolisant, a wake-promoting agent devoid of psychostimulant properties: Preclinical comparison with amphetamine, modafinil, and solriamfetol.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Uptake Inhibitors; Amphetamine; Animals; Carbamates; Corpus Striatum; Disorders of Excessive Somnolence; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Drug Evaluation, Preclinical; Drug Inverse Agonism; Feeding Behavior; Histamine Antagonists; Locomotion; Mice; Modafinil; Narcolepsy; Neostriatum; Norepinephrine Plasma Membrane Transport Proteins; Nucleus Accumbens; Phenylalanine; Piperidines; Receptors, Histamine H3; Sleep Apnea, Obstructive; Wakefulness-Promoting Agents | 2021 |