3,4-dihydroxyphenylacetic acid has been researched along with oxidopamine in 330 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 68 (20.61) | 18.7374 |
| 1990's | 136 (41.21) | 18.2507 |
| 2000's | 89 (26.97) | 29.6817 |
| 2010's | 34 (10.30) | 24.3611 |
| 2020's | 3 (0.91) | 2.80 |
| Authors | Studies |
|---|---|
| Jenner, P; Marsden, CD; Rose, S; Thomas, KL | 1 |
| Daszuta, A; Moukhles, H; Nieoullon, A | 1 |
| Clark, WA; Deutch, AY; Goldstein, M; Rosin, DL; Roth, RH | 1 |
| Finch, CE; Kelly, AB; Kohama, S; Morgan, DG; Osterburg, HH; Pasinetti, GM; Reinhard, JF; Stellwagen, RH | 1 |
| Crock, R; Pehek, EA; Yamamoto, BK | 1 |
| Huston, JP; Mattioli, R; Schwarting, RK | 1 |
| Castañeda, E; Fiorino, D; Mittleman, G; Whishaw, IQ | 1 |
| al-Tikriti, MS; Innis, RB; Kessler, RM; Roth, RH | 1 |
| De Klippel, N; Deleu, D; Devrieze, A; Ebinger, G; Herregodts, P; Michotte, Y; Sarre, S | 1 |
| Jones, GH; Robbins, TW | 1 |
| Sui, J; Wu, R; Yu, C; Zuo, P | 1 |
| Borrelli, E; Haby, C; Hindelang, C; Lisovoski, F; Revel, MO; Schleef, C; Zwiller, J | 1 |
| Castañeda, E; Lermer, L; Robinson, TE; Whishaw, IQ | 1 |
| Castañeda, E; Robinson, TE; Whishaw, IQ | 1 |
| Colpaert, FC; Lategan, AJ; Marien, MR | 1 |
| Brodin, E; Luthman, J; Sundström, E; Wiehager, B | 1 |
| Herrera-Marschitz, M; Kehr, J; Reid, MS; Ungerstedt, U | 1 |
| Krause, JE; Sivam, SP | 1 |
| Le Moal, M; Simon, H; Taghzouti, K | 1 |
| Bledsoe, S; Murphy, J; Zhou, FC | 1 |
| Parker, GC; Rugg, EL; Winn, P | 1 |
| Costentin, J; Naudin, B; Saligaut, C | 1 |
| Bédard, PJ; Di Paolo, T; Gagnon, C; Gaudin, DP; Rioux, L | 1 |
| Alcorn, LM; Lee, HJ; Weiler, MH | 1 |
| Carey, RJ | 3 |
| Hadjiconstantinou, M; Neff, NH; Qu, ZX | 1 |
| Ben-Shachar, D; Eshel, G; Finberg, JP; Youdim, MB | 1 |
| Drumheller, A; Jolicoeur, FB; Rivest, R; St-Pierre, S | 1 |
| Drumheller, A; Jolicoeur, FB; Rivest, R | 1 |
| Hashiguchi, H; Hashitani, T; Ikeda, T; Ishida, Y; Nishino, H; Yamamoto, R | 1 |
| Snyder, GL; Zigmond, MJ | 1 |
| Buu, NT; Lussier, C | 1 |
| Hashitani, T; Ikeda, T; Ishida, Y; Kumazaki, M; Nishino, H | 1 |
| Keller, RW; Snyder, GL; Zigmond, MJ | 1 |
| Bagnoli, P; Buonamici, M; Cervini, MA; Raffaelli, A; Rossi, AC; Sebastiani, L | 1 |
| Bhardwaj, A; Brannan, T; Martinez-Tica, J; Weinberger, J; Yahr, M | 1 |
| Clark, WA; Deutch, AY; Roth, RH | 1 |
| Abercrombie, ED; Keefe, KA; Stricker, EM; Zigmond, MJ | 1 |
| Apicella, P; Dusticier, N; Legallet, E; Nieoullon, A; Trouche, E | 1 |
| Gale, K; Meloni, R | 1 |
| Brannan, T; Kaufmann, H; Knott, P; Yahr, M | 1 |
| Curzon, G; Hutson, PH | 1 |
| Fibiger, HC; Martin-Iverson, MT; Szostak, C | 1 |
| Bradbury, AJ; Costall, B; Domeney, AM; Jenner, PJ; Marsden, CD; Naylor, RJ | 1 |
| Baldessarini, RJ; Barber, NI; Finklestein, SP; Reichheld, JH; Teicher, MH | 1 |
| Alvarez, C; Berger, B; McRae-Degueurce, A; Milon, H; Ornstein, K; Würzner, HP | 1 |
| Bruno, JP; Jackson, D; Stricker, EM; Zigmond, MJ | 1 |
| Ballarin, M; Casas, M; Herrera-Marschitz, M; Ungerstedt, U | 1 |
| Kato, T; Yamamoto, H | 1 |
| Adams, F; Becker, JB; Robinson, TE | 1 |
| Cadet, JL; Fahn, S; Jackson-Lewis, V; Katz, M | 1 |
| Carey, RJ; Lynch, MR | 2 |
| Greenshaw, AJ; Juorio, AV; Nguyen, TV | 1 |
| Altar, CA; Marien, MR | 1 |
| Abercrombie, ED; Zigmond, MJ | 1 |
| Cadet, JL; Fahn, S; Jackson-Lewis, V; Thomas, J | 1 |
| Geula, C; Slevin, JT | 1 |
| Chung, E; Dvorozniak, MT; Li, HC; Van Woert, MH | 1 |
| Edwards, DJ; Knopf, S; Ravitch, J; Sedlock, ML | 1 |
| Fink, G; Sheward, WJ; Smith, GC; Watts, AG | 1 |
| Campbell, KS; Fuchs, BA; Munson, AE | 1 |
| Enz, A; Hefti, F; Melamed, E | 1 |
| Seiden, LS | 1 |
| Chapin, DS; Lookingland, KJ; McKay, DW; Moore, KE | 1 |
| Abrous, N; Herman, JP; Le Moal, M; Rivet, JM | 1 |
| Busto, R; Dietrich, WD; Ginsberg, MD; Globus, MY; Martinez, E; Valdes, I | 1 |
| Bédard, P; Di Paolo, T; Falardeau, P; Rouillard, C | 1 |
| Björklund, A; Brundin, P; Gage, FH; Isacson, O | 1 |
| Baden, DR; Kenny, AM; Murrin, LC; Pfeiffer, RF; Schneider, MB | 1 |
| Boudet, C; Cottet-Emard, JM; Dalmaz, Y; Peyrin, L; Simon, H | 1 |
| Brunette, JR; Drumheller, AL; Jolicoeur, FB; Lafond, G; Olivier, P | 1 |
| Biziere, K; Gonon, F; Mermet, C; Steinberg, R; Suaud-Chagny, MF | 1 |
| Adam, M; Boyes, BE; Cumming, P; Grierson, J; Martin, WR; McGeer, EG; Ruth, T | 1 |
| Le Moal, M; Oades, RD; Rivet, JM; Simon, H; Taghzouti, K | 1 |
| Amalric, M; Koob, GF | 1 |
| Fibiger, HC; Jakubovic, A; LePiane, FG; Phillips, AG | 1 |
| Harry, GJ; Hong, JS; Hudson, PM; Nanry, K; Tilson, HA | 1 |
| Bixler, GB; Dunn, AJ; Eaker, EY; Mathias, JR; Moreshead, WV | 1 |
| Laping, NJ; Ramirez, VD | 1 |
| Deminière, JM; Le Moal, M; Simon, H; Taghzouti, K; Tassin, JP | 1 |
| Bitran, D; Holmes, GM; Hull, EM; Lookingland, KJ | 1 |
| Carlsson, A; Hajos, M; Hjorth, S; Svensson, K | 1 |
| Robinson, TE; Whishaw, IQ | 1 |
| Baird, JL; Glick, SD; Hinds, PA | 1 |
| Radhakishun, FS; van Ree, JM; Wolterink, G | 1 |
| Forler, C; Palfreyman, MG; Robin, M | 1 |
| Buu, NT | 1 |
| Choulli, K; Herman, JP; Le Moal, M | 1 |
| Koob, GF; Swerdlow, NR | 1 |
| Blaha, CD; Lane, RF | 1 |
| Stricker, EM; Zigmond, MJ | 1 |
| Dravid, A; Enz, A; Frei, P; Jaton, AL | 1 |
| Feenstra, MG; Horn, AS; Mulder, TB; Rollema, H; Westerink, BH | 1 |
| Korf, J; Sebens, JB; Vaalburg, W; van der Werf, JF | 1 |
| Burgess, SK; Kalivas, PW; Nemeroff, CB; Prange, AJ | 1 |
| Coates, G; Garnett, S; Heyes, MP | 1 |
| Altar, CA; Marshall, JF; O'Neil, S | 1 |
| Kubos, KL; Moran, TH; Robinson, RG; Saad, KM | 1 |
| Seiden, LS; Vosmer, G | 1 |
| Deupree, JD; Murrin, LC; Pfeiffer, RF; Schneider, MB | 1 |
| Bloom, FE; Ettenberg, A; Koob, GF; Pettit, HO | 1 |
| Herman, JP; Le Moal, M; Stinus, L | 1 |
| Blanc, G; Glowinski, J; Herve, D; Tassin, JP | 1 |
| McRae-Degueurce, A; Milon, H | 1 |
| Dayton, MA; Ewing, AG; Wightman, RM | 1 |
| Bruneau, N; Cottet-Emard, JM; Le Moal, M; Peyrin, L; Simon, H | 1 |
| Gramsbergen, JB; Sloot, WN; van der Sluijs-Gelling, AJ | 1 |
| Camp, DM; Mocsary, Z; Robinson, TE; Whishaw, IQ | 1 |
| Altar, CA; Boylan, CB; Fritsche, M; Hyman, C; Jackson, C; Jones, BE; Lindsay, RM; Wiegand, SJ | 1 |
| Sivam, SP | 1 |
| Hagino, H; Kurachi, M; Kurachi, T; Kurata, K; Murata, M; Sakurai, Y; Shibata, R; Suzuki, M; Tanii, Y; Yasui, S | 1 |
| Finlay, JM; King, D | 2 |
| Amalric, M; Daszuta, A; Moukhles, H; Nieoullon, A | 1 |
| Bankiewicz, KS; Finberg, JP; Goldstein, DS; Kopin, IJ; Wang, J | 1 |
| Loupe, PS; Schroeder, SR; Stodgell, CJ; Tessel, RE | 1 |
| Boix, F; Fornaguera, J; Huston, JP; Schwarting, RK | 1 |
| Bickford, P; Friedemann, M; Gerhardt, GA; Hoffer, BJ; Luthman, J; Olson, L | 1 |
| Castello, ME; Costa, G; Dajas, F; Greenfield, S; Jerusalinsky, D; Levesque, D; Medina, J; Silveira, R | 1 |
| Brannan, T; Martínez-Tica, J; Yahr, MD | 1 |
| Ambrosio, S; Bartrons, R; Calopa, M; Espino, A; Llorens, J; Rodriguez-Farré, E | 1 |
| King, LA; Kita, T; Lowndes, HE; Philbert, MA; Wagner, GC | 1 |
| Fuller, RW; Hemrick-Luecke, SK; Snoddy, HD | 1 |
| Daszuta, A; Forni, C; Moukhles, H; Nieoullon, A | 1 |
| Brodin, E; Goiny, M; Herrera-Marschitz, M; Hökfelt, T; Meana, JJ; Morino, P; Silveira, R; Ungerstedt, U; You, ZB | 1 |
| Gayrard, V; Malpaux, B; Thiéry, JC; Tillet, Y | 1 |
| Kondoh, T; Low, WC | 1 |
| De Klippel, N; Ebinger, G; Herregodts, P; Michotte, Y; Sarre, S | 1 |
| Cupo, A; Gobaille, S; Herbrecht, F; Maitre, M; Schmidt, C | 1 |
| Sullivan, RM; Szechtman, H | 1 |
| Bubser, M | 1 |
| Baker, G; McGregor, A; Roberts, DC | 2 |
| Asanuma, M; Kawada, Y; Kondo, Y; Mori, A; Ogawa, N; Yamamoto, M | 1 |
| Bruno, JP; Garity, D; Sidhu, KS; Stellar, JR | 1 |
| Pierce, RC; Rebec, GV | 1 |
| De Klippel, N; Ebinger, G; Michotte, Y; Sarre, S | 1 |
| Fraser, A; Sullivan, RM; Szechtman, H | 1 |
| Abercrombie, ED; Wachtel, SR | 1 |
| Cass, WA; Flach, KA; Gerhardt, GA; Zahniser, NR | 1 |
| Abercrombie, ED; Jackson, D; Zigmond, MJ | 1 |
| Hossain, MA; Weiner, N | 1 |
| Cousins, MS; McCullough, LD; Salamone, JD | 1 |
| Salamone, JD; Steinpreis, RE | 1 |
| Florijn, WJ; Gispen, WH; Mulder, AH; Versteeg, DH | 1 |
| Daugé, V; Derrien, M; Durieux, C; Roques, BP | 1 |
| McCullough, LD; Salamone, JD; Sokolowski, JD | 1 |
| Ambrosio, S; Bartrons, R; Cutillas, B; Espino, A; Ferrer, I; Tortosa, A | 1 |
| Bannon, MJ; Brownschidle, LA; D'sa, C; Moody, CA; Poosch, MS; Tian, Y; Whitty, CJ | 1 |
| Adams, FS; Edwards-Prasad, J; Freed, CR; Kentroti, S; Kumar, S; La Rosa, FG; Prasad, KN; Vernadakis, A | 1 |
| Correa, JG; Stoppani, AO | 1 |
| Ehrenström, F; Söderpalm, A; Söderpalm, B | 1 |
| Eisenhofer, G; Gould, L; Hansson, S; Harta, G; Hoffman, BJ; Hunyady, B; Mezey, E | 1 |
| Dall'Olio, R; Gandolfi, O | 1 |
| Atlas, D; Djaldetti, R; Melamed, E | 1 |
| Godukhin, O; Goiny, M; Herrera-Marschitz, M; Hökfelt, T; Kehr, J; Nylander, I; Pettersson, E; Shou, HZ; Terenius, L; Ungerstedt, U; You, ZB | 1 |
| Kabuto, H; Makino, H; Matsuura, K; Ogawa, N | 1 |
| Agnati, LF; Andbjer, B; Cintra, A; Finnman, UB; Fuxe, K; Hagman, M; Höglund, G | 1 |
| Chiou, AL; Tang, FI; Wang, JY; Wang, Y | 1 |
| Hashitani, T; Hattori, S; Matsui, N; Nishino, H | 1 |
| Iacovitti, L; Jin, BK | 1 |
| Dluzen, DE; Xu, K | 1 |
| Finlay, JM; King, D; Zigmond, MJ | 1 |
| Besson, MJ; Durand, C; Herve, D; Penit-Soria, J | 1 |
| Emmi, A; Rajabi, H; Stewart, J | 1 |
| Botterblom, MH; Bubser, M; Erdtsieck-Ernste, EB; Feenstra, MG; Pool, CW; Van Uum, HF | 1 |
| Bickford, PC; Bowenkamp, KE; Hoffer, BJ; Lapchak, PA; Miller, PJ | 1 |
| Arai, T; Ikarashi, Y; Ishimaru, H; Maruyama, Y; Takahashi, A | 1 |
| Makino, H; Matsuura, K; Ogawa, N | 1 |
| Cass, WA; Gash, DM; Kearns, CM; Kryscio, R; Smoot, K | 1 |
| Blunt, SB; Hötten, G; Opacka-Juffry, J; Pohl, J; Sullivan, AM | 1 |
| Dluzen, D | 1 |
| Alvarez, P; Cruz, R; Garciá, JC; Leiva, A; McPherson, M; Soto, Y | 1 |
| Araujo, DM; Hilt, DC; Jiao, S; Lapchak, PA; Sheng, J | 1 |
| Okada, S; Sawashita, J; Takeda, A; Takefuta, S | 1 |
| Hashitani, T; Kumazaki, M; Mizukawa, K; Nishino, H | 1 |
| Armanini, MP; Bjorklund, A; Horger, BA; Hynes, MA; Johnson, E; Kirik, D; Milbrandt, J; Moffat, B; Nishimura, MC; Phillips, HS; Poulsen, KT; Rosenblad, C; Rosenthal, A; Simmons, L; Vandlen, RA; Wang, LC | 1 |
| Andersen, SL; Baldessarini, RJ; Campbell, A; Gelbard, HA; Teicher, MH | 1 |
| Andrés, ME; Bustos, G; Gysling, K | 1 |
| Ebinger, G; Izurieta-Sánchez, P; Michotte, Y; Sarre, S | 1 |
| Blunt, SB; Opacka-Juffry, J; Sullivan, AM | 1 |
| Albin, RL; Becker, JB; Frey, KA; Kearney, JA | 1 |
| Huang, J; Kita, T; Lowndes, HE; Philbert, MA; Wagner, GC | 1 |
| Blunt, SB; Opacka-Juffry, J; Wilson, AW | 1 |
| Abin, JA; Costa, G; Dajas, F; Dajas-Bailador, FA; Martignoni, E; Martinez-Borges, A; Nappi, G | 1 |
| Chen, CF; Chueh, FS; Chueh, FY; Hsieh, MT; Lin, MT; Lin, SM | 1 |
| Jin, BK; Joo, WS; Kim, YS; Maeng, SH; Park, CW | 1 |
| Kannari, K; Maeda, T; Matsunaga, M; Suda, T; Tanaka, H; Tomiyama, M | 2 |
| Damhaut, P; Dethy, S; Goldman, S; Laute, MA | 1 |
| Kaneda, S; Kawai, Y; Matsushita, H; Takeuchi, Y; Ueda, S; Yasuhara, M; Yoshimoto, K; Yuri, K | 1 |
| Buchholz, J; Carlson, JD; Iacono, RP; Maeda, G; Pearlstein, RD | 1 |
| Beyer, CE; Steketee, JD | 1 |
| Blaney, TJ; Cain, CK; Emerich, DF; Frydel, BR; Hoane, MR; Lindner, MD; Plone, MA | 1 |
| Basura, GJ; Walker, PD | 3 |
| Kawahara, H; Kawahara, Y; Westerink, BH | 1 |
| Finlay, JM; Lewis, DA; Venator, DK | 1 |
| Agnati, LF; Aguirre, JA; Andbjer, B; Cintra, A; Finnman, UB; Fuxe, K; Hagman, M; Höglund, C; Möller, A | 1 |
| Iwata-Ichikawa, E; Kabuto, H; Ogawa, N; Yokoi, I | 1 |
| Gentsch, C; Spooren, WP; Waldmeier, P | 1 |
| Berger, SP; Fox, L; Ho, LB; Reid, MS | 1 |
| Grünblatt, E; Mandel, S; Youdim, MB | 1 |
| Ben, V; Blin, O; Bruguerolle, B | 1 |
| Eldrup, E; Richter, EA | 1 |
| Brotchie, JM; Nash, JE | 1 |
| Goldstein, DS; Harvey-White, JD; Kopin, IJ; Yadid, G | 1 |
| Kupsch, A; Meissner, W; Morgenstern, R; Paul, G; Reese, R; Reum, T; Sohr, R | 1 |
| Jenner, P; Rose, S; Treseder, SA | 1 |
| Halladay, AK; Michna, L; Wagner, GC; Widmer, DA; Yue, Y; Zhou, R | 1 |
| Abin-Carriquiry, JA; Costa, G; Dajas, F | 1 |
| Baklaushev, VP; Chekhonin, VP; Dmitrieva, TB; Filatova, TS; Kogan, BM; Lebedev, SV; Man'kovskaya, IV; Savchenko, EA; Yusupova, IU | 1 |
| Bertrand, A; Bruet, N; Feuerstein, C; Poupard, A; Savasta, M; Windels, F | 1 |
| Dentresangle, C; Le Cavorsin, M; Leviel, V; Savasta, M | 1 |
| Al Deeb, S; Al Moutaery, K; Khan, HA; Tariq, M | 1 |
| Espejo, EF; Miñano, J | 1 |
| Baklaushev, VP; Belopasov, VV; Chekhonin, VP; Dmitrieva, TB; Filatova, TS; Kogan, BM; Lazarenko, IP; Lebedev, SV; Man'kovskaya, IV; Savchenko, EA | 1 |
| Cass, WA; Fox, CM; Gash, DM; Smoot, MK | 1 |
| Harnack, D; Kupsch, A; Meissner, W; Morgenstern, R; Paul, G; Reum, T; Sohr, R | 2 |
| Fujiwara, M; Hatip-Al-Khatib, I; Iwasaki, K; Mishima, K | 1 |
| Cohen, AD; Miller, GW; Philhower, J; Schallert, T; Tillerson, JL; Zigmond, MJ | 1 |
| Borrelli, E; Drago, J; Finkelstein, DI; Horne, MK; Parish, CL | 1 |
| Campbell, BM; Gresch, PJ; Walker, PD | 1 |
| Ferger, B; Schmidt, N; Schulz, JB; Teismann, P; Xia, XG | 1 |
| Barthwal, MK; Dikshit, M; Srivastava, N | 1 |
| Chen, JF; Cuellar, B; Fredduzzi, S; Impagnatiello, F; Monopoli, A; Moratalla, R; Ongini, E; Schwarzschild, MA; Xu, K | 1 |
| Bölükbasi, F; Egashira, N; Fujiwara, M; Hatip-Al-khati, I; Iwasaki, K; Mishima, K | 1 |
| Aguiar, LM; Sousa, FC; Vasconcelos, SM; Viana, GS | 1 |
| Breese, GR; Friedmann, T; Jinnah, HA; Moy, SS; Rothstein, JD; Smith, DW; Visser, JE | 1 |
| Caudle, WM; Cohen, AD; Miller, GW; Schallert, T; Tillerson, JL; Zigmond, MJ | 1 |
| Bardo, MT; Brown, RW; Dwoskin, LP; Green, TA; Phillips, SB | 1 |
| Datla, KP; Dexter, DT; Gillies, GE; Murray, HE; Pillai, AV | 1 |
| Cohen, AD; Schallert, T; Smith, AD; Tillerson, JL; Zigmond, MJ | 1 |
| Schmidt, WJ; Srinivasan, J | 2 |
| Bishop, C; Walker, PD | 1 |
| Agrawal, AK; Chaturvedi, RK; Chauhan, S; Seth, K; Seth, PK; Shukla, S; Shukla, Y; Sinha, C | 1 |
| Ben Shachar, D; Stephenson, G; Youdim, MB | 1 |
| Aruoma, OI; Bahorun, T; Bennett, RD; Datla, KP; Dexter, DT; Higa, T; Ke, B; Liang, YF; Zbarsky, V | 1 |
| Finberg, JP; Gross, A; Moses, D | 1 |
| Gluck, MR; Granson, H; Santana, LA; Yahr, MD | 1 |
| Aubin, N; Barneoud, P; Burnier, P; Caille, D; Carter, C; Charieras, T; Curet, O; Gardes, A; George, P; Jegham, S; Le Kim, A; Lolivier, J; Marc, C; Pandini, M; Perron, C; Puech, F; Scatton, B; Sontag, N | 1 |
| Itakura, T; Kakishita, K; Nakao, N; Shintani-Mizushima, A | 1 |
| Agrawal, AK; Ahmad, A; Chaturvedi, RK; Seth, K; Seth, PK; Shukla, S; Srivastava, N | 1 |
| Moroz, IA; Peciña, S; Schallert, T; Stewart, J | 1 |
| Agrawal, AK; Chaturvedi, RK; Khanna, VK; Seth, K; Seth, PK; Shukla, S; Shukla, Y; Sinha, C; Srivastava, N | 1 |
| Ebinger, G; Michotte, Y; Sarre, S; Yuan, H | 2 |
| Harsing, LG; Juranyi, Z; Levay, G; Marko, B; Sziray, N | 1 |
| Ogawa, N; Tanaka, K | 1 |
| Bohn, MC; Kozlowski, DA; Smith, AD; Zigmond, MJ | 1 |
| Asanuma, M; Diaz-Corrales, FJ; Miyazaki, I; Ogawa, N; Shimizu, M; Tanaka, K | 1 |
| Ahmad, AS; Ahmad, M; Ansari, MA; Hoda, MN; Islam, F; Saleem, S; Yousuf, S | 1 |
| Baker, D; Cabranes, A; de Lago, E; Fernández-Ruiz, J; López-Rodríguez, M; Ortega-Gutiérrez, S; Pryce, G; Ramos, JA | 1 |
| Higashio, C; Kabuto, H; Kohno, M; Nishizawa, M; Shishibori, T; Tada, M | 1 |
| Bishop, C; Taylor, JL; Walker, PD | 1 |
| Datla, KP; Dexter, DT; Zbarsky, V | 1 |
| Boyce, PJ; Finlay, JM | 1 |
| Ding, JH; Hu, G; Hu, LF; Liu, X; Yang, J; Zhou, F | 1 |
| Aruoma, OI; Datla, KP; Dexter, DT; Parkar, S; Rai, DK; Zbarsky, V | 1 |
| Clinton, SM; Finlay, JM; Sucharski, IL | 1 |
| Agrawal, AK; Chaturvedi, RK; Seth, K; Shukla, S | 2 |
| Cox, J; Sivam, SP | 1 |
| Dowd, E; Fitzsimmons, DF; Moloney, TC | 1 |
| Bezard, E; Bioulac, B; Boraud, T; Gross, CE; Harnack, D; Klitgaard, H; Kupsch, A; Meissner, W; Morgenstern, R; Ravenscroft, P; Reese, R | 1 |
| Bongiovanni, MJ; Kuczenski, R; Neary, AC; Saint Marie, RL; Shoemaker, JM; Swerdlow, NR; Tochen, LS | 1 |
| Meck, WH | 1 |
| Enna, SJ; Reisman, SA; Stanford, JA | 1 |
| Cannon, JR; Hua, Y; Keep, RF; Richardson, RJ; Schallert, T; Xi, G | 1 |
| Croucher, MJ; Datla, KP; Dexter, DT; Vernon, AC; Zbarsky, V | 1 |
| Chang, JW; Hwang, YS; Lee, BB; Shim, I | 1 |
| Gacsalyi, I; Harsing, LG; Juranyi, Z; Levay, G; Marko, B; Megyeri, K; Sziray, N | 1 |
| Bortel, A; Brus, R; Dabrowska, J; Drosik, M; Kostrzewa, RM; Kwiecinski, A; Nowak, P; Opara, J; Oswiecimska, J | 1 |
| Daniel, WA; Gołembiowska, K; Wójcikowski, J | 1 |
| Bertrand, A; Boulet, S; Carcenac, C; Feuerstein, C; Lacombe, E; Poupard, A; Savasta, M | 1 |
| Barbanoj, M; Kulisevsky, J; Pérez, V; Rodríguez-Alvarez, J; Rubio, A; Sosti, V | 1 |
| Aosaki, T; Fuwa, T; Honda, Y; Hua-Qin, W; Ikeda, T; Imai, Y; Inoue, H; Ito, S; Itohara, S; Kaneko, S; Kataoka, A; Kodama, T; Masuda, M; Matsumoto, S; Miura, M; Soda, M; Takahashi, R; Tsukita, K; Wakamatsu, K | 1 |
| Buck, K; Ferger, B | 1 |
| Chen, H; Jing, FC; Li, CL; Tu, PF; Wang, ZH; Zheng, QS | 1 |
| Castelli, MP; Devoto, P; Ennas, MG; Flore, G; Gessa, GL; Luesu, W; Piras, AP; Saba, P; Viaggi, MC | 1 |
| Debetto, P; Giusti, P; Guidolin, D; Negro, A; Peroni, D; Recchia, A; Rota, D; Skaper, SD | 1 |
| Adkins, DL; Allred, RP; Husbands, LC; Jones, TA; Kane, JR; Maldonado, MA; Schallert, T; Woodlee, MT | 1 |
| Artusi, R; Caselli, G; Lanza, M; Makovec, F; Michotte, Y; Sarre, S | 1 |
| Amakawa, M; Kabuto, H; Mankura, M; Mori, A; Yamanushi, TT | 1 |
| An, L; Cheng, B; Gao, B; Liu, S; Liu, X; Yang, X | 1 |
| Kostrzewa, RA; Kostrzewa, RM; Nowak, P; Skaba, D | 1 |
| Celik, M; Korkmaz, OT; Oncü, EM; Sahintürk, V; Tunçel, M; Tunçel, N | 1 |
| Chung, CY; Hallett, PJ; Isacson, O; Koprich, JB | 1 |
| Bertrand, A; Dentresangle, C; Detraz, I; Dzahini, K; Le Cavorsin, M; Leviel, V; Savasta, M | 1 |
| Agnati, LF; Aguirre, JA; Fuxe, K; Hagman, B; Kehr, J; Marcellino, D; Rivera, A; Sánchez-Reina, MD; Suárez-Boomgaard, D; Yoshitake, S; Yoshitake, T | 1 |
| Di Giovanni, G; di Matteo, V; Dragani, LK; Esposito, E; Murzilli, S; Pierucci, M; Poggi, A | 1 |
| Borah, A; Mohanakumar, KP | 1 |
| Chung, YC; Han, EH; Huang, GB; Li, CR; Sui, ZY | 1 |
| Bethel-Brown, CS; Chertoff, ME; Fowler, SC; Stanford, JA; Watson, GS; Zhang, H | 1 |
| Cass, WA; Peters, LE | 1 |
| Chung, YC; Huang, GB; Kim, KW; Kwon, YB; Lee, KH; Li, CR; Sui, ZY | 1 |
| Andersson, M; Bergstrom, BP; Carroll, FI; Garris, PA; Mithyantha, J; Sanberg, SG | 1 |
| Dziubina, A; Gołembiowska, K | 1 |
| Chao, OY; Huston, JP; Pum, ME; von Bothmer, A | 1 |
| Amalric, M; Blobaum, AL; Bode, J; Bridges, TM; Bubser, M; Conn, PJ; Daniels, JS; Dickerson, JW; Engers, DW; Hopkins, CR; Italiano, K; Jadhav, S; Jones, CK; Lindsley, CW; Morrison, RD; Niswender, CM; Thompson, AD; Turle-Lorenzo, N | 1 |
| Ahmad, S; Bhatia, K; Fazili, IS; Haque, R; Hoda, MN; Jamal, A; Katare, DP; Khan, JS; Khan, MB | 1 |
| Chao, OY; Huston, JP; Mattern, C; Nikolaus, S; Pum, ME; Ruocco, LA; Silva, AM; Wessler, J | 1 |
| Lin, L; Liu, TT; Meng, T; Zheng, ZH | 1 |
| Breyer, MD; Breyer, RM; Deguchi, Y; Furuyashiki, T; Imoto, Y; Kitaoka, S; Narumiya, S; Segi-Nishida, E; Senzai, Y; Tanaka, K | 1 |
| Barnhart, TE; Brunner, KG; Emborg, ME; Engle, JW; Goecks, NC; Hacker, TA; Holden, JE; Joers, V; Kamp, TJ; Nickles, RJ; Seneczko, K | 1 |
| Berghauzen, K; Kolasiewicz, W; Kuter, K; Nowak, P; Ossowska, K; Schulze, G | 1 |
| Lin, L; Liu, T; Meng, T; Zheng, Z | 1 |
| Huston, JP; Petri, D; Pum, M; Schnitzler, A; Vesper, J | 1 |
| Gao, Y; Han, B; Hu, J; Lu, Y; Shen, J; Wang, T | 1 |
| Kuwabara, S; Sakakibara, R; Taniguchi, J; Uchiyama, T; Yamamoto, T | 1 |
| Czarnecka, A; Kamińska, K; Konieczny, J; Lenda, T; Lorenc-Koci, E | 1 |
| Cavalheiro, EA; Cerqueira, GS; Correia, AO; de Barros Viana, GS; de Castro Brito, GA; Machado-Filho, JA; Montenegro, AB; Naffah-Mazzacoratti, Mda G; Neves, KR; Nobre, ME | 1 |
| Chen, G; Feng, J; Feng, W; Huang, Z; Niu, J; Shi, L; Wang, Y; Ye, C; Zhu, G | 1 |
| Han, B; Jin, HJ; Song, MY; Wang, T; Zhao, H | 1 |
| Bähr, M; Koch, JC; Lingor, P; Michel, U; Ribas, VT; Saal, KA; Szegő, EM; Tatenhorst, L; Tönges, L | 1 |
| Czarnecka, A; Kamińska, K; Konieczny, J; Lenda, T; Nowak, P | 1 |
| Bouchard, RS; Gittis, AH; Willard, AM | 1 |
| Antunes, MS; Boeira, SP; Goes, ATR; Jesse, CR; Lobo Ladd, AAB; Lobo Ladd, FV; Luchese, C; Paroul, N | 1 |
| Berta, B; Gálosi, R; Kállai, V; Kovács, A; Lénárd, L; Ollmann, T; Péczely, L; Petykó, Z; Tóth, A | 1 |
| Bähr, M; Cheng, S; Déglon, N; Konstantinova, P; Kügler, S; Liefhebber, J; Mazur, A; Pythoud, C; Raina, A; Rey, M; Streit, F; Tereshchenko, J; Vachey, G; Zimmer, V | 1 |
| Boeira, SP; Cattelan Souza, L; de Gomes, MG; Del Fabbro, L; Furian, AF; Jesse, CR; Lobo Ladd, AAB; Lobo Ladd, FV; Nunes Arantes, RV; Oliveira, MS; Reis Simionato, A; Rossito Goes, A | 1 |
| Kostrzewa, JP; Kostrzewa, RM | 1 |
| Antunes, MS; Boeira, SP; Cattelan Souza, L; Ladd, AABL; Ladd, FVL; Moreira, AL | 1 |
| da Costa, RO; de Aquino, PEA; de Barros Viana, GS; de Lucena, JD; Gadelha-Filho, CVJ; Lima, FAV; Lima, LAR; Neves, KRT; Ribeiro, WLC | 1 |
1 trial(s) available for 3,4-dihydroxyphenylacetic acid and oxidopamine
| Article | Year |
|---|---|
The ability of grafted human sympathetic neurons to synthesize and store dopamine: a potential mechanism for the clinical effect of sympathetic neuron autografts in patients with Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Aromatic-L-Amino-Acid Decarboxylases; Brain Tissue Transplantation; Corpus Striatum; Denervation; Disease Models, Animal; Dopamine; Female; Ganglia, Sympathetic; Graft Survival; Humans; Levodopa; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Neurons; Neuropeptides; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Reserpine; Transplantation, Heterologous; Tyrosine 3-Monooxygenase; Up-Regulation; Vesicular Biogenic Amine Transport Proteins; Vesicular Monoamine Transport Proteins | 2004 |
329 other study(ies) available for 3,4-dihydroxyphenylacetic acid and oxidopamine
| Article | Year |
|---|---|
Dissociation of the striatal D-2 dopamine receptor from adenylyl cyclase following 6-hydroxydopamine-induced denervation.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 3,4-Dihydroxyphenylacetic Acid; Adenylyl Cyclases; Animals; Benzazepines; Corpus Striatum; Cyclic AMP; Denervation; Dopamine; Ergolines; Female; Homovanillic Acid; Oxidopamine; Prosencephalon; Quinpirole; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Spiperone | 1992 |
Early and widespread normalization of dopamine-neuropeptide Y interactions in the rat striatum after transplantation of fetal mesencephalon cells.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Brain Tissue Transplantation; Corpus Striatum; Dextroamphetamine; Dopamine; Female; Fetal Tissue Transplantation; Immunohistochemistry; Mesencephalon; Neuropeptide Y; Oxidopamine; Rats; Rats, Inbred Strains; Stereotyped Behavior; Substantia Nigra; Tyrosine 3-Monooxygenase | 1992 |
Effects of 6-hydroxydopamine lesions of the prefrontal cortex on tyrosine hydroxylase activity in mesolimbic and nigrostriatal dopamine systems.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cerebral Cortex; Corpus Striatum; Dopamine; Limbic System; Male; Norepinephrine; Nucleus Accumbens; Oxidopamine; Rats; Rats, Inbred Strains; Reference Values; Substantia Nigra; Tyrosine 3-Monooxygenase | 1992 |
Slow changes of tyrosine hydroxylase gene expression in dopaminergic brain neurons after neurotoxin lesioning: a model for neuron aging.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Amino Acid Sequence; Animals; Biogenic Monoamines; Corpus Striatum; Dopamine; Gene Expression Regulation, Enzymologic; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Immunohistochemistry; Male; Molecular Sequence Data; Neurons; Norepinephrine; Nucleic Acid Hybridization; Oxidopamine; Rats; Rats, Inbred F344; RNA, Messenger; Sequence Homology, Nucleic Acid; Serotonin; Substantia Nigra; Tyrosine 3-Monooxygenase | 1992 |
Selective subregional dopamine depletions in the rat caudate-putamen following nigrostriatal lesions.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Caudate Nucleus; Corpus Striatum; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Nerve Degeneration; Oxidopamine; Putamen; Rats; Rats, Inbred Strains; Serotonin; Substantia Nigra; Sympathectomy, Chemical | 1992 |
Recovery from unilateral 6-hydroxydopamine lesion of substantia nigra promoted by the neurotachykinin substance P 1-11.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Dopamine; Homovanillic Acid; Male; Norepinephrine; Oxidopamine; Rats; Rats, Inbred Strains; Substance P; Substantia Nigra; Sympathectomy, Chemical; Tachykinins | 1992 |
Do forebrain structures compete for behavioral expression? Evidence from amphetamine-induced behavior, microdialysis, and caudate-accumbens lesions in medial frontal cortex damaged rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Analysis of Variance; Animals; Biogenic Monoamines; Caudate Nucleus; Cerebral Cortex; Corpus Striatum; Dialysis; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Motor Activity; Nucleus Accumbens; Oxidopamine; Prosencephalon; Rats; Stereotaxic Techniques; Stereotyped Behavior; Time Factors | 1992 |
Autoradiographic localization of dopamine D1 and D2 receptors in rat cerebral cortex following unilateral neurotoxic lesions.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Autoradiography; Binding Sites; Cerebral Cortex; Dopamine; Ibotenic Acid; Male; Oxidopamine; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Synaptosomes | 1992 |
Biotransformation of L-dopa in striatum and substantia nigra of rats with a unilateral, nigrostriatal lesion: a microdialysis study.
Topics: 3,4-Dihydroxyphenylacetic Acid; Anesthetics; Animals; Biotransformation; Corpus Striatum; Dialysis; Dopamine; Extracellular Space; Homovanillic Acid; Levodopa; Male; Oxidopamine; Rats; Rats, Wistar; Substantia Nigra | 1992 |
Differential effects of mesocortical, mesolimbic, and mesostriatal dopamine depletion on spontaneous, conditioned, and drug-induced locomotor activity.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Caudate Nucleus; Conditioning, Operant; Corpus Striatum; Dextroamphetamine; Dopamine; Limbic System; Male; Motor Activity; Oxidopamine; Prefrontal Cortex; Putamen; Rats; Sympathectomy, Chemical | 1992 |
Metabolism in and function of the central dopamine system after transplanting adrenal medullary tissue into the rat brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenal Medulla; Animals; Brain; Dopamine; Female; Male; Norepinephrine; Oxidopamine; Prosencephalon; Rats; Rats, Wistar; Substantia Nigra | 1992 |
Induction of D2 dopamine receptor mRNA synthesis in a 6-hydroxydopamine parkinsonian rat model.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Blotting, Northern; Corpus Striatum; Dopamine; Female; Homovanillic Acid; Neurons, Efferent; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; RNA, Messenger; Spiperone; Stereotyped Behavior; Substantia Nigra | 1992 |
Dopamine depletion in neonatal rats: effects on behavior and striatal dopamine release assessed by intracerebral microdialysis during adulthood.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Animals, Newborn; Behavior, Animal; Corpus Striatum; Dopamine; Female; Hydroxydopamines; Hydroxyindoleacetic Acid; Male; Oxidopamine; Rats | 1990 |
Changes in striatal dopamine neurotransmission assessed with microdialysis following recovery from a bilateral 6-OHDA lesion: variation as a function of lesion size.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Brain Diseases; Corpus Striatum; Dialysis; Dopamine; Extracellular Space; Homovanillic Acid; Hydroxydopamines; Hydroxyindoleacetic Acid; Male; Osmolar Concentration; Oxidopamine; Rats; Synaptic Transmission | 1990 |
Effects of locus coeruleus lesions on the release of endogenous dopamine in the rat nucleus accumbens and caudate nucleus as determined by intracerebral microdialysis.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Caudate Nucleus; Chromatography, High Pressure Liquid; Dextroamphetamine; Dialysis; Dopamine; Hydroxydopamines; Hydroxyindoleacetic Acid; Limbic System; Locus Coeruleus; Male; Norepinephrine; Nucleus Accumbens; Oxidopamine; Rats; Rats, Inbred Strains; Sympathectomy, Chemical | 1990 |
Studies on brain monoamine and neuropeptide systems after neonatal intracerebroventricular 6-hydroxydopamine treatment.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Amines; Brain; Cerebral Ventricles; Cholecystokinin; Desipramine; Dopamine; Hydroxydopamines; Hydroxyindoleacetic Acid; Injections, Intraventricular; Male; Neuropeptides; Neurotensin; Neurotoxins; Norepinephrine; Organ Specificity; Oxidopamine; Rats; Rats, Inbred Strains; Reference Values; Serotonin; Substance P; Tyrosine 3-Monooxygenase | 1990 |
Striatal dopamine and glutamate release: effects of intranigral injections of substance P.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Denervation; Dopamine; Dopamine Agents; Glutamates; Glutamic Acid; Hydroxydopamines; Male; Oxidopamine; Rats; Rats, Inbred Strains; Substance P; Substantia Nigra | 1990 |
The adaptation of enkephalin, tachykinin and monoamine neurons of the basal ganglia following neonatal dopaminergic denervation is dependent on the extent of dopamine depletion.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adaptation, Physiological; Animals; Animals, Newborn; Basal Ganglia; Biogenic Monoamines; Chromatography, High Pressure Liquid; Denervation; Dopamine; Enkephalin, Methionine; Female; Hydroxydopamines; Hydroxyindoleacetic Acid; Male; Neurons; Nucleic Acid Hybridization; Oxidopamine; Radioimmunoassay; Rats; Rats, Inbred Strains; RNA, Messenger; Serotonin; Substance P | 1990 |
Suppression of noradrenergic innervation compensates for behavioral deficits induced by lesion of dopaminergic terminals in the lateral septum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cerebellum; Cerebral Cortex; Desipramine; Dopamine; Efferent Pathways; Hydroxyindoleacetic Acid; Learning; Locus Coeruleus; Male; Norepinephrine; Nucleus Accumbens; Oxidopamine; Rats; Rats, Inbred Strains; Reference Values; Septum Pellucidum; Serotonin | 1991 |
Serotonergic sprouting is induced by dopamine-lesion in substantia nigra of adult rat brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Functional Laterality; Globus Pallidus; Homovanillic Acid; Hydroxyindoleacetic Acid; Nerve Fibers; Nerve Regeneration; Neurons; Oxidopamine; Rats; Rats, Inbred Strains; Reference Values; Serotonin; Substantia Nigra; Tyrosine 3-Monooxygenase | 1991 |
Cholinergic stimulation of substantia nigra: abolition of carbachol-induced eating by unilateral 6-hydroxydopamine lesion of nigrostriatal dopamine neurones.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Mapping; Carbachol; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Feeding Behavior; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Microinjections; Oxidopamine; Rats; Rats, Inbred Strains; Reference Values; Serotonin; Stereotaxic Techniques; Substantia Nigra | 1991 |
Influence of oxygen availability on the neurotoxic effect of 6-hydroxydopamine on nigro-striatal dopaminergic neurons.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Atmospheric Pressure; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Homovanillic Acid; In Vitro Techniques; Injections, Intraventricular; Male; Membrane Proteins; Mice; Nerve Tissue Proteins; Nervous System Diseases; Neurons; Oxidopamine; Oxygen; Substantia Nigra; Synaptosomes | 1991 |
Decrease of behavioral and biochemical denervation supersensitivity of rat striatum by nigral transplants.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Apomorphine; Brain Tissue Transplantation; Corpus Striatum; Denervation; Dopamine; Ergolines; Fetal Tissue Transplantation; Homovanillic Acid; Indoles; Mesencephalon; Motor Activity; Oxidopamine; Phenanthridines; Quinpirole; Rats; Receptors, Dopamine; Substantia Nigra | 1991 |
Effects of various experimental manipulations on neostriatal acetylcholine and dopamine release.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcholine; Animals; Choline; Corpus Striatum; Dopamine; In Vitro Techniques; Kinetics; Male; Norepinephrine; Oxidopamine; Physostigmine; Potassium; Rats; Rats, Inbred F344 | 1991 |
Chronic L-dopa treatment in the unilateral 6-OHDA rat: evidence for behavioral sensitization and biochemical tolerance.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Carbidopa; Corpus Striatum; Denervation; Drug Tolerance; Functional Laterality; Homovanillic Acid; Levodopa; Male; Motor Activity; Oxidopamine; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome | 1991 |
Differential changes of retina dopamine binding sites and adenylyl cyclase responses following 6-hydroxydopamine treatment.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adenylyl Cyclases; Animals; Chromatography, High Pressure Liquid; Cyclic AMP; Dopamine; Hydroxydopamines; Kinetics; Male; Oxidopamine; Protein Binding; Rats; Rats, Inbred Strains; Receptors, Dopamine; Retina | 1991 |
The iron chelator desferrioxamine (Desferal) retards 6-hydroxydopamine-induced degeneration of nigrostriatal dopamine neurons.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Deferoxamine; Dopamine; Homovanillic Acid; Hydroxydopamines; Iron Chelating Agents; Male; Nerve Degeneration; Neurons; Neurotoxins; Oxidopamine; Rats; Rats, Inbred Strains; Substantia Nigra | 1991 |
Antiparkinson-like effects of neurotensin in 6-hydroxydopamine lesioned rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antiparkinson Agents; Behavior, Animal; Brain Chemistry; Catalepsy; Dopamine; Dose-Response Relationship, Drug; Homovanillic Acid; Hydroxydopamines; Hypothalamus; Injections, Intraventricular; Male; Neurotensin; Norepinephrine; Oxidopamine; Parkinson Disease, Secondary; Rats; Sympathectomy, Chemical | 1991 |
Hypokinesia, rigidity, and tremor induced by hypothalamic 6-OHDA lesions in the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Dopamine; Dyskinesia, Drug-Induced; Homovanillic Acid; Humans; Hydroxydopamines; Hypothalamus, Posterior; Male; Muscle Rigidity; Oxidopamine; Parkinson Disease; Rats; Tremor | 1991 |
Effect of intra-amygdala dopaminergic grafts on methamphetamine-induced locomotor activity, extracellular dopamine and dopamine metabolite overflow: a comparison with the effect of intra-accumbens grafts.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amygdala; Animals; Brain Tissue Transplantation; Dopamine; Electrophysiology; Homovanillic Acid; Hydroxydopamines; Male; Methamphetamine; Motor Activity; Nucleus Accumbens; Oxidopamine; Rats; Rats, Inbred Strains | 1991 |
The effects of L-dopa on in vitro dopamine release from striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Calcium; Corpus Striatum; Dopamine; Hydroxydopamines; In Vitro Techniques; Levodopa; Male; Oxidopamine; Rats; Rats, Inbred Strains | 1990 |
Origin of dopamine in the rat adrenal cortex.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenal Cortex; Animals; Dopamine; Epinephrine; Hydroxydopamines; Levodopa; Male; Monoamine Oxidase; Norepinephrine; Oxidopamine; Rats; Rats, Inbred Strains | 1990 |
Behavioral and biochemical effects of intra-accumbens dopaminergic grafts.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Dopamine; Graft Survival; Hydroxydopamines; Male; Mesencephalon; Methamphetamine; Motor Activity; Neurotoxins; Nucleus Accumbens; Oxidopamine; Rats; Rats, Inbred Strains; Septal Nuclei | 1990 |
Dopamine efflux from striatal slices after intracerebral 6-hydroxydopamine: evidence for compensatory hyperactivity of residual terminals.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Electric Stimulation; Evoked Potentials; Hydroxydopamines; Male; Motor Neurons; Nomifensine; Oxidopamine; Rats; Rats, Inbred Strains | 1990 |
Injections of 6-hydroxydopamine in the substantia nigra of the rat brain: morphological and biochemical effects.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Brain Mapping; Caudate Nucleus; Dominance, Cerebral; Dopamine; Hydroxydopamines; Male; Motor Activity; Nerve Fibers; Neurons; Nucleus Accumbens; Oxidopamine; Phenylacetates; Putamen; Rats; Rats, Inbred Strains; Receptors, Dopamine; Stereotyped Behavior; Substantia Nigra; Tegmentum Mesencephali | 1990 |
Striatal L-dopa metabolism studied in vivo in rats with nigrostriatal lesions.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Homovanillic Acid; Hydroxydopamines; Levodopa; Male; Oxidopamine; Rats; Rats, Inbred Strains; Substantia Nigra | 1990 |
Prefrontal cortical dopamine depletion enhances the responsiveness of mesolimbic dopamine neurons to stress.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Frontal Lobe; Hydroxydopamines; Male; Neural Pathways; Neurotoxins; Nucleus Accumbens; Oxidopamine; Rats; Rats, Inbred Strains; Stress, Physiological | 1990 |
Environmental stress increases extracellular dopamine in striatum of 6-hydroxydopamine-treated rats: in vivo microdialysis studies.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cerebral Ventricles; Corpus Striatum; Dopamine; Electroshock; Extracellular Space; Homovanillic Acid; Hydroxydopamines; Male; Oxidopamine; Rats; Rats, Inbred Strains; Reference Values; Stress, Psychological | 1990 |
Motor impairments and neurochemical changes after unilateral 6-hydroxydopamine lesion of the nigrostriatal dopaminergic system in monkeys.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Choline O-Acetyltransferase; Corpus Striatum; Dopamine; Female; Forelimb; Glutamate Decarboxylase; Hydroxydopamines; Male; Movement Disorders; Neurologic Examination; Neurons; Oxidopamine; Papio; Serotonin; Substantia Nigra | 1990 |
Differential regulation of dopamine metabolism in solid fetal substantia nigra transplants and their terminals in the host striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Apomorphine; Brain Tissue Transplantation; Corpus Striatum; Dopamine; Feedback; Fetal Tissue Transplantation; Homovanillic Acid; Hydroxydopamines; Male; Nerve Endings; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Substantia Nigra | 1990 |
In vivo studies of striatal dopamine release and metabolism following administration of L-dopa.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Carbidopa; Corpus Striatum; Dopamine; Homovanillic Acid; Hydroxydopamines; Levodopa; Male; Neural Pathways; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Substantia Nigra; Synaptic Transmission | 1990 |
Dopamine metabolites in rat cisternal cerebrospinal fluid: major contribution from extrastriatal dopamine neurones.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benzylamines; Brain Chemistry; Cerebral Cortex; Corpus Striatum; Dopamine; Hippocampus; Homovanillic Acid; Humans; Hydroxydopamines; Hydroxyindoleacetic Acid; Male; Neurons; Norepinephrine; Oxidopamine; Rats; Rats, Inbred Strains; Serotonin | 1986 |
6-Hydroxydopamine lesions of the medial prefrontal cortex fail to influence intravenous self-administration of cocaine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Cerebral Cortex; Cocaine; Conditioning, Operant; Dopamine; Hydroxydopamines; Hydroxyindoleacetic Acid; Male; Nucleus Accumbens; Oxidopamine; Rats; Self Administration; Serotonin | 1986 |
The neurotoxic actions of 6-hydroxydopamine infused into the rat substantia nigra.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Homovanillic Acid; Hydroxydopamines; Hydroxyindoleacetic Acid; Male; Movement Disorders; Neurotransmitter Agents; Oxidopamine; Pyridines; Pyridinium Compounds; Rats; Rats, Inbred Strains; Substantia Nigra | 1986 |
Selective depletion of cerebral norepinephrine with 6-hydroxydopamine and GBR-12909 in neonatal rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Animals, Newborn; Brain Chemistry; Dopamine; Female; Homovanillic Acid; Hydroxydopamines; Hydroxyindoleacetic Acid; Male; Norepinephrine; Oxidopamine; Piperazines; Rats; Rats, Inbred Strains; Serotonin | 1986 |
Biochemical and radioautographic evidence for dopaminergic afferents of the locus coeruleus originating in the ventral tegmental area.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Autoradiography; Dopamine; Homovanillic Acid; Hydroxydopamines; Hydroxyindoleacetic Acid; Locus Coeruleus; Male; Neural Pathways; Neurons, Afferent; Norepinephrine; Nucleus Accumbens; Oxidopamine; Rats; Septal Nuclei; Serotonin; Tegmentum Mesencephali | 1987 |
Effect of dopamine-depleting brain lesions in rat pups: role of striatal serotonergic neurons in behavior.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Animals, Newborn; Behavior, Animal; Brain; Corpus Striatum; Dopamine; Female; Hydroxydopamines; Hydroxyindoleacetic Acid; Male; Neurons; Oxidopamine; Rats; Rats, Inbred Strains; Serotonin | 1987 |
Striatal adenosine levels measured 'in vivo' by microdialysis in rats with unilateral dopamine denervation.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adenosine; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Denervation; Dialysis; Dopamine; Guanosine; Homovanillic Acid; Hydroxydopamines; Hydroxyindoleacetic Acid; Hypoxanthine; Hypoxanthines; Inosine; Male; Oxidopamine; Rats; Rats, Inbred Strains | 1987 |
Effects on brain cholecystokinin-8-sulfate and serotonin in adult rats after neonatal reduction of catecholamines.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Animals, Newborn; Brain; Catecholamines; Desipramine; Hydroxydopamines; Hydroxyindoleacetic Acid; Oxidopamine; Rats; Rats, Inbred Strains; Serotonin; Sincalide | 1988 |
Intraventricular microdialysis: a new method for determining monoamine metabolite concentrations in the cerebrospinal fluid of freely moving rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenal Medulla; Animals; Cerebral Ventricles; Dialysis; Dopamine; Female; Haloperidol; Homovanillic Acid; Hydroxydopamines; Hydroxyindoleacetic Acid; Oxidopamine; Phenylacetates; Probenecid; Rats; Substantia Nigra | 1988 |
Vitamin E attenuates the toxic effects of intrastriatal injection of 6-hydroxydopamine (6-OHDA) in rats: behavioral and biochemical evidence.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Drug Interactions; Homovanillic Acid; Hydroxydopamines; Male; Oxidopamine; Rats; Rats, Inbred Strains; Stereotyped Behavior; Vitamin E | 1989 |
Amphetamine-induced rotation reveals post 6-OHDA lesion neurochemical reorganization.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dextroamphetamine; Dominance, Cerebral; Dopamine; Homovanillic Acid; Hydroxydopamines; Limbic System; Male; Mesencephalon; Neural Pathways; Nucleus Accumbens; Olfactory Bulb; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Stereotyped Behavior; Substantia Nigra | 1989 |
Lesion-induced reductions in trace amine accumulation: dependence on MAO inhibitor pretreatment.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Amines; Corpus Striatum; Dopamine; Homovanillic Acid; Hydroxydopamines; Male; Monoamine Oxidase Inhibitors; Oxidopamine; Pargyline; Rats; Rats, Inbred Strains; Selegiline; Substantia Nigra; Tryptamines | 1989 |
Preservation of dopamine release in the denervated striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Homovanillic Acid; Hydroxydopamines; Male; Oxidopamine; Rats; Rats, Inbred Strains; Substantia Nigra | 1989 |
Mesolimbic dopamine and early post-6-OHDA lesion enhanced responses to d-amphetamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Dextroamphetamine; Dopamine; Homovanillic Acid; Hydroxydopamines; Limbic System; Male; Motor Activity; Oxidopamine; Rats; Rats, Inbred Strains | 1989 |
Partial injury to central noradrenergic neurons: reduction of tissue norepinephrine content is greater than reduction of extracellular norepinephrine measured by microdialysis.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Injuries; Electroshock; Hippocampus; Hydroxydopamines; Male; Neurons; Norepinephrine; Oxidopamine; Potassium; Rats; Rats, Inbred Strains | 1989 |
Methylprednisolone treatments alter apomorphine-induced circling in the rat model of 6-hydroxydopamine-induced striatal denervation.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Corpus Striatum; Denervation; Dopamine; Hydroxydopamines; Male; Methylprednisolone; Oxidopamine; Rats; Rats, Inbred Strains; Stereotyped Behavior | 1989 |
Substantia nigra 6-hydroxydopamine lesions alter dopaminergic synaptic markers in the nucleus basalis magnocellularis and striatum of rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Basal Ganglia; Corpus Striatum; Dopamine; Hydroxydopamines; Male; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Substantia Nigra; Sulpiride | 1989 |
Regional distribution of calcium/calmodulin-dependent phosphatase activity of calcineurin in rat brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Calcineurin; Calcium; Calmodulin; Calmodulin-Binding Proteins; Corpus Striatum; Dopamine; Glutamate Decarboxylase; Homovanillic Acid; Hydroxydopamines; Kainic Acid; Male; Oxidopamine; Phosphoprotein Phosphatases; Phosphoric Monoester Hydrolases; Rats; Rats, Inbred Strains; Substantia Nigra; Sympathectomy, Chemical | 1989 |
Effects of intraventricular injections of 6-hydroxydopamine on amine metabolites in rat brain and urine.
Topics: 3-Methoxy-4-hydroxyphenylethanol; 3,4-Dihydroxyphenylacetic Acid; Adrenal Glands; Animals; Biogenic Amines; Brain Chemistry; Dopamine; Ethylene Glycols; Gas Chromatography-Mass Spectrometry; Heart; Homovanillic Acid; Hydroxydopamines; Injections, Intraventricular; Male; Methoxyhydroxyphenylglycol; Norepinephrine; Organ Size; Oxidopamine; Phenols; Phenylethyl Alcohol; Rats; Rats, Inbred Strains; Spleen | 1985 |
Effects of intravenously administered 6-hydroxydopamine on the content of monoamines in the median eminence and neurointermediate lobe of the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Catecholamines; Dopamine; Hydroxydopamines; Hydroxyindoleacetic Acid; Injections, Intravenous; Male; Median Eminence; Norepinephrine; Oxidopamine; Pituitary Gland, Anterior; Rats; Rats, Inbred Strains; Serotonin | 1985 |
Norepinephrine and serotonin content of the murine spleen: its relationship to lymphocyte beta-adrenergic receptor density and the humoral immune response in vivo and in vitro.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antigens; Female; Hemolytic Plaque Technique; Hydroxydopamines; In Vitro Techniques; Lymphocytes; Mice; Norepinephrine; Oxidopamine; Receptors, Adrenergic, beta; Serotonin; Spleen; Sympathetic Nervous System | 1988 |
Partial lesions of the nigrostriatal pathway in the rat. Acceleration of transmitter synthesis and release of surviving dopaminergic neurones by drugs.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; gamma-Aminobutyric Acid; Haloperidol; Homovanillic Acid; Hydroxydopamines; Male; Morphine; Neurons; Neurotransmitter Agents; Oxidopamine; Rats; Rats, Inbred Strains; Substantia Nigra | 1985 |
Methamphetamine: toxicity to dopaminergic neurons.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Dopamine; Guinea Pigs; Hydroxydopamines; Kinetics; Macaca mulatta; Methamphetamine; Mice; Nerve Endings; Neurons; Neurotransmitter Agents; Norepinephrine; Oxidopamine; Rats; Receptors, Dopamine; Serotonin; Spiperone; Substance-Related Disorders | 1985 |
Comparative effects of the neurotoxins N-chloroethyl-N-ethyl-2-bromobenzylamine hydrochloride (DSP4) and 6-hydroxydopamine on hypothalamic noradrenergic, dopaminergic and 5-hydroxytryptaminergic neurons in the male rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amines; Animals; Benzylamines; Brain Chemistry; Dopamine; Hydroxydopamines; Hypothalamus; Male; Neurotransmitter Agents; Norepinephrine; Oxidopamine; Rats; Serotonin | 1986 |
Intracerebral dopaminergic transplants are not activated by electrical footshock stress activating in situ mesocorticolimbic neurons.
Topics: 3,4-Dihydroxyphenylacetic Acid; Afferent Pathways; Animals; Dopamine; Electroshock; Graft Survival; Hydroxydopamines; Male; Motor Activity; Nucleus Accumbens; Oxidopamine; Rats; Rats, Inbred Strains; Septal Nuclei; Tegmentum Mesencephali; Tyrosine 3-Monooxygenase | 1988 |
Effect of ischemia on the in vivo release of striatal dopamine, glutamate, and gamma-aminobutyric acid studied by intracerebral microdialysis.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cerebrovascular Circulation; Corpus Striatum; Denervation; Dialysis; Dopamine; Energy Metabolism; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Homovanillic Acid; Hydroxydopamines; Ischemic Attack, Transient; Kinetics; Male; Oxidopamine; Rats; Rats, Inbred Strains; Substantia Nigra | 1988 |
Repeated stimulation of D-1 dopamine receptors increases the circling response to bromocriptine in rats with a 6-OHDA lesion.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 3,4-Dihydroxyphenylacetic Acid; Animals; Appetite Depressants; Benzazepines; Bromocriptine; Corpus Striatum; Dopamine; Female; Homovanillic Acid; Hydroxydopamines; Locomotion; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Substantia Nigra | 1988 |
Relationship of limbic dopamine levels to amphetamine- and anticholinergic-induced hyperactivity in the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dextroamphetamine; Dopamine; Hydroxydopamines; Limbic System; Male; Motor Activity; Nucleus Accumbens; Olfactory Bulb; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Scopolamine | 1986 |
Intrastriatal grafting of dopamine-containing neuronal cell suspensions: effects of mixing with target or non-target cells.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Corpus Striatum; Dopamine; Female; Functional Laterality; Histocytochemistry; Hydroxydopamines; Mesencephalon; Neurons; Oxidopamine; Rats; Rats, Inbred Strains; Spinal Cord; Suspensions | 1986 |
Bromocriptine holiday: effects on dopamine receptors and turning behavior in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Binding Sites; Bromocriptine; Dopamine; Drug Administration Schedule; Hydroxydopamines; Male; Oxidopamine; Parkinson Disease; Parkinson Disease, Secondary; Rats; Rats, Inbred Strains; Receptors, Dopamine; Stereotyped Behavior; Substantia Nigra; Time Factors | 1986 |
Striatal and mesolimbic dopaminergic contribution to 3,4-dihydroxyphenylacetic acid sulfate in rat plasma.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Catecholamines; Corpus Striatum; Dopamine; Hydroxydopamines; Limbic System; Male; Nucleus Accumbens; Oxidopamine; Phenylacetates; Rats | 1986 |
Relationship of changes in spontaneous motor activity to spontaneous circling in rats with unilateral 6-hydroxydopamine lesions of the substantia nigra.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Brain; Corpus Striatum; Dopamine; Homovanillic Acid; Hydroxydopamines; Limbic System; Male; Motor Activity; Neurons; Oxidopamine; Rats; Rats, Inbred Strains; Substantia Nigra | 1986 |
Dose related effects of 6-OHDA on rabbit retinal dopamine concentrations and ERG B-wave amplitudes.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Dopamine; Dose-Response Relationship, Drug; Electroretinography; Homovanillic Acid; Hydroxydopamines; Microinjections; Oxidopamine; Rabbits; Retina; Vitreous Body | 1986 |
In vivo voltammetric monitoring of catecholamine metabolism in the A1 and A2 regions of the rat medulla oblongata.
Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Methyltyrosine; Animals; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Catecholamines; Clonidine; Dopamine; Electrochemistry; Hydroxydopamines; Kinetics; Male; Medulla Oblongata; Methoxyhydroxyphenylglycol; Methyltyrosines; Norepinephrine; Oxidopamine; Pargyline; Rats; Tissue Distribution | 1986 |
The metabolism of [18F]6-fluoro-L-3,4-dihydroxyphenylalanine in the hooded rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Caudate Nucleus; Dihydroxyphenylalanine; Hydroxydopamines; Male; Oxidopamine; Rats; Rats, Inbred Strains | 1987 |
Locomotor activity in relation to dopamine and noradrenaline in the nucleus accumbens, septal and frontal areas: a 6-hydroxydopamine study.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Circadian Rhythm; Dopamine; Frontal Lobe; Hydroxydopamines; Male; Motor Activity; Norepinephrine; Nucleus Accumbens; Oxidopamine; Rats; Rats, Inbred Strains; Septal Nuclei | 1986 |
Depletion of dopamine in the caudate nucleus but not in nucleus accumbens impairs reaction-time performance in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Caudate Nucleus; Conditioning, Operant; Dopamine; Flupenthixol; Hydroxydopamines; Male; Nucleus Accumbens; Oxidopamine; Rats; Rats, Inbred Strains; Reaction Time; Septal Nuclei | 1987 |
The role of dopamine in intracranial self-stimulation of the ventral tegmental area.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Diseases; Corpus Striatum; Dopamine; Electric Stimulation; Homovanillic Acid; Hydroxydopamines; Male; Nucleus Accumbens; Olfactory Bulb; Oxidopamine; Rats; Reinforcement, Psychology; Tegmentum Mesencephali | 1987 |
Ganglioside interactions with the dopaminergic system of rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Corpus Striatum; Dopamine; Gangliosides; Haloperidol; Hydroxydopamines; Injections; Injections, Intraventricular; Male; Motor Activity; Oxidopamine; Rats; Rats, Inbred F344; Substantia Nigra | 1988 |
Dopamine and norepinephrine in the gastrointestinal tract of mice and the effects of neurotoxins.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Digestive System; Dopamine; Hydroxydopamines; Intestinal Mucosa; Male; Mice; Myenteric Plexus; Neurotoxins; Norepinephrine; Oxidopamine; Pyridines | 1988 |
Prolactin-induced yawning behavior requires an intact nigro-striatal dopamine system.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Corpus Striatum; Dopamine; Hydroxydopamines; Male; Oxidopamine; Physostigmine; Prolactin; Rats; Substantia Nigra; Sympathectomy, Chemical; Yawning | 1988 |
Increased sensitivity to amphetamine and facilitation of amphetamine self-administration after 6-hydroxydopamine lesions of the amygdala.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Amygdala; Animals; Cardiac Catheterization; Dextroamphetamine; Dose-Response Relationship, Drug; Hydroxydopamines; Male; Motor Activity; Norepinephrine; Nucleus Accumbens; Oxidopamine; Rats; Rats, Inbred Strains; Self Administration; Sympathectomy, Chemical | 1988 |
Regulation of male rat copulatory behavior by preoptic incertohypothalamic dopamine neurons.
Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Methyltyrosine; Animals; Apomorphine; Brain; Copulation; Dopamine; Dose-Response Relationship, Drug; Hydroxydopamines; Male; Methyltyrosines; Oxidopamine; Preoptic Area; Rats; Sexual Behavior, Animal | 1988 |
In vivo dopamine (DA) receptor binding and behavioural effects of the putative DA autoreceptor antagonists (+)-AJ 76 and (+)-UH 232 in rats with a unilateral nigral 6-OH-DA lesion.
Topics: 3,4-Dihydroxyphenylacetic Acid; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Apomorphine; Behavior, Animal; Functional Laterality; Hydroxydopamines; Male; Naphthalenes; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Substantia Nigra; Tetrahydronaphthalenes | 1988 |
Normalization of extracellular dopamine in striatum following recovery from a partial unilateral 6-OHDA lesion of the substantia nigra: a microdialysis study in freely moving rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamines; Animals; Corpus Striatum; Dopamine; Female; Homovanillic Acid; Hydroxydopamines; Oxidopamine; Rats; Stereotyped Behavior; Substantia Nigra | 1988 |
Two kinds of nigrostriatal asymmetry: relationship to dopaminergic drug sensitivity and 6-hydroxydopamine lesion effects in Long-Evans rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamines; Animals; Apomorphine; Corpus Striatum; Dopamine; Female; Functional Laterality; Homovanillic Acid; Hydroxydopamines; Male; Oxidopamine; Pergolide; Rats; Species Specificity; Substantia Nigra | 1988 |
The response of apomorphine administered into the accumbens in rats with bilateral lesions of the nucleus accumbens, induced with 6-hydroxydopamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Dopamine; Homovanillic Acid; Hydroxydopamines; Male; Motor Activity; Nucleus Accumbens; Oxidopamine; Rats; Rats, Inbred Strains; Septal Nuclei | 1988 |
Effect of chronic apomorphine on the development of denervation supersensitivity.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Behavior, Animal; Brain Chemistry; Corpus Striatum; Denervation; Desipramine; Dopamine; Homovanillic Acid; Hydroxydopamines; Injections; Male; Medial Forebrain Bundle; Norepinephrine; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine | 1985 |
Dopamine sulfoconjugation in the rat brain: regulation by monoamine oxidase.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Brain Chemistry; Brain Stem; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Homovanillic Acid; Hydroxydopamines; Hypothalamus; Male; Monoamine Oxidase; Oxidopamine; Pargyline; Rats; Rats, Inbred Strains | 1985 |
Activation of striatal dopaminergic grafts by haloperidol.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Corpus Striatum; Denervation; Dopamine; Female; Haloperidol; Hydroxydopamines; Motor Activity; Nerve Regeneration; Oxidopamine; Rats; Rats, Inbred Strains | 1985 |
The neural substrates of apomorphine-stimulated locomotor activity following denervation of the nucleus accumbens.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Caudate Nucleus; Dopamine; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Hydroxydopamines; Male; Motor Activity; Muscimol; Neurons, Efferent; Norepinephrine; Nucleus Accumbens; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, GABA-A; Septal Nuclei | 1984 |
Direct in vivo electrochemical monitoring of dopamine release in response to neuroleptic drugs.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antipsychotic Agents; Ascorbic Acid; Brain; Chlorpromazine; Dopamine; Electrochemistry; Extracellular Space; Haloperidol; Hydroxydopamines; Male; Oxidopamine; Pargyline; Rats; Rats, Inbred Strains | 1984 |
Parkinson's disease: studies with an animal model.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Disease Models, Animal; Dopamine; Electrophysiology; Haloperidol; Haplorhini; Hydroxydopamines; Mice; Oxidopamine; Parkinson Disease; Rats; Tyrosine 3-Monooxygenase | 1984 |
Spontaneous recovery from motor asymmetry in adult rats with 6-hydroxydopamine-induced partial lesions of the substantia nigra.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Apomorphine; Dopamine; Female; Functional Laterality; Homovanillic Acid; Hydroxydopamines; Motor Activity; Oxidopamine; Rats; Rats, Inbred Strains; Substantia Nigra; Tyrosine 3-Monooxygenase | 1984 |
In vivo dopamine receptor binding studies with a non-radioactively labeled agonist, dipropyl-5,6-ADTN.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Cerebellum; Corpus Striatum; Domperidone; Female; Homovanillic Acid; Hydroxydopamines; Male; Methysergide; Naphthalenes; Occipital Lobe; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Sympatholytics; Tetrahydronaphthalenes; Tranquilizing Agents | 1983 |
In vivo binding of N-n-propylnorapomorphine in the rat brain: regional localization, quantification in striatum and lack of correlation with dopamine metabolism.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Binding Sites; Brain; Chemical Phenomena; Chemistry; Corpus Striatum; Dopamine; Homovanillic Acid; Hydroxydopamines; Male; Oxidopamine; Rats; Rats, Inbred Strains; Time Factors | 1983 |
Behavioral and neurochemical effects of neurotensin microinjection into the ventral tegmental area of the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Haloperidol; Homovanillic Acid; Hydroxydopamines; Male; Microinjections; Motor Activity; Neurotensin; Nucleus Accumbens; Olfactory Bulb; Oxidopamine; Rats; Rats, Inbred Strains; Tegmentum Mesencephali | 1983 |
Rapid identification of correctly located intracerebroventricular cannula in the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Catheterization; Cerebral Ventriculography; Corpus Striatum; Dopamine; Hydroxydopamines; Hypothalamus; Injections, Intraventricular; Male; Norepinephrine; Oxidopamine; Rats; Rats, Inbred Strains; Thorium Dioxide | 1983 |
Sensorimotor impairment and elevated levels of dopamine metabolites in the neostriatum occur rapidly after intranigral injection of 6-hydroxydopamine or gamma-hydroxybutyrate in awake rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; 4-Butyrolactone; Animals; Biotransformation; Corpus Striatum; Dopamine; Homovanillic Acid; Hydroxybutyrates; Hydroxydopamines; Male; Microinjections; Oxidopamine; Procaine; Psychomotor Performance; Rats; Rats, Inbred Strains; Sodium Oxybate; Substantia Nigra | 1984 |
Asymmetrical locomotor response to unilateral cortical injections of DSP-4.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amines; Animals; Behavior, Animal; Benzylamines; Caudate Nucleus; Cerebral Cortex; Dopamine; Functional Laterality; Hydroxydopamines; Injections; Locus Coeruleus; Male; Motor Activity; Norepinephrine; Oxidopamine; Rats; Rats, Inbred Strains; Serotonin; Substantia Nigra | 1984 |
Formation of 6-hydroxydopamine in caudate nucleus of the rat brain after a single large dose of methylamphetamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Caudate Nucleus; Dopamine; Hydroxydopamines; Male; Methamphetamine; Nervous System Diseases; Oxidopamine; Rats; Rats, Inbred Strains | 1984 |
Dopamine receptors: effects of chronic L-dopa and bromocriptine treatment in an animal model of Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Bromocriptine; Corpus Striatum; Disease Models, Animal; Dopamine; Humans; Hydroxydopamines; Kinetics; Levodopa; Male; Membranes; Oxidopamine; Parkinson Disease; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Stereotyped Behavior; Substantia Nigra | 1984 |
Destruction of dopamine in the nucleus accumbens selectively attenuates cocaine but not heroin self-administration in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cocaine; Dopamine; Heroin; Hydroxydopamines; Male; Norepinephrine; Nucleus Accumbens; Oxidopamine; Rats; Rats, Inbred Strains; Self Administration; Septal Nuclei | 1984 |
Repeated stress increases locomotor response to amphetamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Methyltyrosine; Amphetamine; Amygdala; Animals; Apomorphine; Cerebral Cortex; Dopamine; Humans; Hydroxydopamines; Limbic System; Male; Methyltyrosines; Motor Activity; Norepinephrine; Nucleus Accumbens; Oxidopamine; Rats; Rats, Inbred Strains; Stress, Psychological | 1984 |
Reduction of dopamine utilization in the prefrontal cortex but not in the nucleus accumbens after selective destruction of noradrenergic fibers innervating the ventral tegmental area in the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cerebral Cortex; Dopamine; Hydroxydopamines; Male; Norepinephrine; Nucleus Accumbens; Organ Specificity; Oxidopamine; Rats; Rats, Inbred Strains; Septal Nuclei; Tegmentum Mesencephali | 1982 |
Pharmacological investigation on the role of dopamine in the rat locus coeruleus.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Chromatography, High Pressure Liquid; Desipramine; Dopamine; Haloperidol; Hydroxydopamines; Locus Coeruleus; Male; Norepinephrine; Oxidopamine; Pargyline; Phenylacetates; Rats; Rats, Inbred Strains | 1982 |
In vivo voltammetry with electrodes that discriminate between dopamine and ascorbate.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Ascorbic Acid; Brain; Caudate Nucleus; Cerebral Cortex; Corpus Striatum; Dominance, Cerebral; Dopamine; Electrochemistry; Hydroxydopamines; Male; Oxidopamine; Potassium; Rats; Rats, Inbred Strains | 1982 |
6-Hydroxydopamine lesions of dopaminergic A10 neurons. Long-term effects on the urinary excretion of free and conjugated catecholamines and their metabolites in the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Catecholamines; Dopamine; Homovanillic Acid; Hydroxydopamines; Male; Oxidopamine; Rats; Rats, Inbred Strains; Tegmentum Mesencephali | 1982 |
Selective lesions by manganese and extensive damage by iron after injection into rat striatum or hippocampus.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Basal Ganglia; Biogenic Amines; Calcium; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Functional Laterality; Hippocampus; Homovanillic Acid; Hydroxyindoleacetic Acid; Iron; Kinetics; Male; Manganese; Manganese Poisoning; Neurotoxins; Norepinephrine; Oxidopamine; Rats; Rats, Wistar; Serotonin; Time Factors | 1994 |
Time course of recovery of extracellular dopamine following partial damage to the nigrostriatal dopamine system.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Extracellular Space; Female; Homovanillic Acid; Hydroxyindoleacetic Acid; Kinetics; Microdialysis; Oxidopamine; Rats; Rats, Sprague-Dawley; Reference Values; Substantia Nigra; Time Factors | 1994 |
Efficacy of brain-derived neurotrophic factor and neurotrophin-3 on neurochemical and behavioral deficits associated with partial nigrostriatal dopamine lesions.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Brain-Derived Neurotrophic Factor; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Motor Activity; Nerve Growth Factors; Nerve Tissue Proteins; Neurotrophin 3; Oxidopamine; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Serotonin; Substantia Nigra | 1994 |
Dopaminergic modulation of serotonin metabolism in rat striatum: a study with dopamine uptake inhibitor GBR-12909.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Dopamine Uptake Inhibitors; Female; Hydroxyindoleacetic Acid; Oxidopamine; Piperazines; Rats; Rats, Sprague-Dawley; Serotonin | 1995 |
Hypofrontality does not occur with 6-hydroxydopamine lesions of the medial prefrontal cortex in rat brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Dopamine; Glucose; Hydroxyindoleacetic Acid; Male; Oxidopamine; Prefrontal Cortex; Rats; Rats, Wistar | 1995 |
Effects of selective dopamine depletion in medial prefrontal cortex on basal and evoked extracellular dopamine in neostriatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Basal Metabolism; Dopamine; Fluorescent Dyes; Homovanillic Acid; Male; Microdialysis; Neostriatum; Nerve Endings; Neurons; Oxidopamine; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Stilbamidines | 1995 |
Complex deficits on reaction time performance following bilateral intrastriatal 6-OHDA infusion in the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Disease Models, Animal; Dopamine; Frontal Lobe; Homovanillic Acid; Immunohistochemistry; Male; Oxidopamine; Parkinson Disease; Rats; Rats, Wistar; Reaction Time; Task Performance and Analysis | 1995 |
Influence of selective inhibition of monoamine oxidase A or B on striatal metabolism of L-DOPA in hemiparkinsonian rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Clorgyline; Corpus Striatum; Dialysis; Dopamine; Homovanillic Acid; Indans; Levodopa; Male; Monoamine Oxidase Inhibitors; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Selegiline; Substantia Nigra | 1995 |
Reversal of 6HD-induced neonatal brain catecholamine depletion after operant training.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Animals, Newborn; Brain Chemistry; Catecholamines; Cerebral Cortex; Conditioning, Operant; Dopamine; Homovanillic Acid; Male; Neostriatum; Neuronal Plasticity; Oxidopamine; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Sympathectomy, Chemical | 1995 |
Behavioral indices of moderate nigro-striatal 6-hydroxydopamine lesion: a preclinical Parkinson's model.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Apomorphine; Corpus Striatum; Dopamine; Functional Laterality; Homovanillic Acid; Hydroxyindoleacetic Acid; Locomotion; Male; Motor Activity; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Wistar; Serotonin; Substantia Nigra | 1993 |
In vivo electrochemical measurements and electrophysiological studies of rat striatum following neonatal 6-hydroxydopamine treatment.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Animals, Newborn; Ascorbic Acid; Corpus Striatum; Dopamine; Electrochemistry; Electrophysiology; Functional Laterality; Glutamates; Glutamic Acid; Homovanillic Acid; Hydroxyindoleacetic Acid; Kinetics; Male; Neurons; Oxidopamine; Rats; Rats, Sprague-Dawley; Reference Values; Serotonin; Time Factors | 1993 |
Differential cholinergic and non-cholinergic actions of acetylcholinesterase in the substantia nigra revealed by fasciculin-induced inhibition.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcholinesterase; Animals; Apomorphine; Biogenic Amines; Cell Membrane; Cholinesterase Inhibitors; Dopamine; Elapid Venoms; Functional Laterality; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Motor Activity; Norepinephrine; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Rotation; Serotonin; Substantia Nigra | 1993 |
Effect of repeated electroconvulsive shock on striatal L-dopa and dopamine metabolism: an in vivo study.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Catecholamines; Corpus Striatum; Dopamine; Electroshock; Extracellular Space; Homovanillic Acid; Hydroxyindoleacetic Acid; Levodopa; Male; Microdialysis; Oxidopamine; Rats; Rats, Sprague-Dawley; Substantia Nigra | 1993 |
Cerebrospinal dopamine metabolites in rats after intrastriatal administration of 6-hydroxydopamine or 1-methyl-4-phenylpyridinium ion.
Topics: 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; gamma-Aminobutyric Acid; Homovanillic Acid; Male; Motor Activity; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley | 1995 |
Effects of pargyline and pyrogallol on the methamphetamine-induced dopamine depletion.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Male; Methamphetamine; Oxidopamine; Pargyline; Pyrogallol; Rats; Rats, Sprague-Dawley; Reference Values; Time Factors | 1995 |
Fluoxetine at anorectic doses does not have properties of a dopamine uptake inhibitor.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Appetite Depressants; Brain Chemistry; Dopamine; Dopamine Uptake Inhibitors; Fluoxetine; Homovanillic Acid; Injections, Intraventricular; Male; Mazindol; Neostriatum; Oxidopamine; Rats; Rats, Sprague-Dawley | 1994 |
Regulation of dopamine levels in intrastriatal grafts of fetal mesencephalic cell suspension: an in vivo voltammetric approach.
Topics: 2-Amino-5-phosphonovalerate; 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Benzazepines; Brain Tissue Transplantation; Cerebral Ventricles; Corpus Striatum; Dizocilpine Maleate; Dopamine; Dopamine D2 Receptor Antagonists; Female; Fetal Tissue Transplantation; Glutamic Acid; Injections, Intraventricular; Kinetics; Mesencephalon; N-Methylaspartate; Oxidopamine; Quisqualic Acid; Rats; Rats, Wistar; Receptors, Dopamine D1; Sulpiride; Time Factors; Transplantation, Heterotopic | 1994 |
On the origin of striatal cholecystokinin release: studies with in vivo microdialysis.
Topics: 3,4-Dihydroxyphenylacetic Acid; Afferent Pathways; Animals; Aspartic Acid; Calcium; Cholecystokinin; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Glutamates; Glutamic Acid; Homovanillic Acid; Male; Microdialysis; Oxidopamine; Potassium; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Sincalide | 1994 |
Estradiol increases tyrosine hydroxylase activity of the A15 nucleus dopaminergic neurons during long days in the ewe.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Caudate Nucleus; Dialysis; Dopamine; Estradiol; Female; Homovanillic Acid; Hypothalamus; Levodopa; Luteinizing Hormone; Neurons; Nomifensine; Norepinephrine; Ovariectomy; Oxidopamine; Photoperiod; Sheep; Tyrosine 3-Monooxygenase | 1994 |
Glutamate uptake blockade induces striatal dopamine release in 6-hydroxydopamine rats with intrastriatal grafts: evidence for host modulation of transplanted dopamine neurons.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Brain Diseases; Brain Tissue Transplantation; Corpus Striatum; Dopamine; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Kainic Acid; Male; Mesencephalon; N-Methylaspartate; Neurons; Oxidopamine; Rats; Tyrosine 3-Monooxygenase | 1994 |
Biotransformation of locally applied L-dopa in the corpus striatum of the hemi-parkinsonian rat studied with microdialysis.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benserazide; Biotransformation; Corpus Striatum; Denervation; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Homovanillic Acid; Levodopa; Male; Microdialysis; Nomifensine; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Wistar; Tetrodotoxin | 1994 |
Characterization of methionine-enkephalin release in the rat striatum by in vivo dialysis: effects of gamma-hydroxybutyrate on cellular and extracellular methionine-enkephalin levels.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benzocycloheptenes; Corpus Striatum; Dopamine; Enkephalin, Methionine; Male; Microdialysis; Oxidopamine; Rats; Rats, Wistar; Receptors, Dopamine; Sodium Oxybate; Sulpiride; Tetrodotoxin; Veratridine | 1994 |
Left/right nigrostriatal asymmetry in susceptibility to neurotoxic dopamine depletion with 6-hydroxydopamine in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Chromatography, High Pressure Liquid; Dopamine; Functional Laterality; Male; Neostriatum; Oxidopamine; Rats; Rats, Sprague-Dawley; Substantia Nigra | 1994 |
6-Hydroxydopamine lesions of the medial prefrontal cortex of rats do not affect dopamine metabolism in the basal ganglia at short and long postsurgical intervals.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Basal Ganglia; Corpus Striatum; Dopamine; Homovanillic Acid; Male; Nucleus Accumbens; Oxidopamine; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Time Factors | 1994 |
Effect of 6-hydroxydopamine lesions of the amygdala on intravenous cocaine self-administration under a progressive ratio schedule of reinforcement.
Topics: 3,4-Dihydroxyphenylacetic Acid; 5,7-Dihydroxytryptamine; Amygdala; Analysis of Variance; Animals; Behavior, Animal; Benzazepines; Brain; Chlordiazepoxide; Cocaine; Desipramine; Dopamine; Estrus; Female; Fluoxetine; Ibotenic Acid; Injections, Intravenous; Male; Organ Specificity; Oxidopamine; Rats; Rats, Wistar; Self Administration; Time Factors; Tryptophan | 1994 |
Differential effects of chronic L-dopa treatment on lipid peroxidation in the mouse brain with or without pretreatment with 6-hydroxydopamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Catecholamines; Homovanillic Acid; Levodopa; Lipid Peroxidation; Male; Mice; Mice, Inbred ICR; Nerve Tissue Proteins; Neurons; Oxidopamine; Thiobarbituric Acid Reactive Substances | 1994 |
6-OHDA-treated weanling rats show normal neuroleptic sensitivity as adults on LHSS.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antipsychotic Agents; Brain Chemistry; Chromatography, High Pressure Liquid; Dopamine; Dose-Response Relationship, Drug; Electrodes, Implanted; Homovanillic Acid; Hypothalamic Area, Lateral; Injections, Intraventricular; Male; Motor Activity; Oxidopamine; Pimozide; Rats; Rats, Sprague-Dawley; Reward; Self Stimulation; Sympathectomy, Chemical | 1993 |
Intraneostriatal administration of glutamate antagonists increases behavioral activation and decreases neostriatal ascorbate via nondopaminergic mechanisms.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Ascorbic Acid; Dizocilpine Maleate; Glutamates; Glutamic Acid; Homocysteine; Infusions, Parenteral; Male; Motor Activity; Neostriatum; Oxidopamine; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Stereotyped Behavior | 1993 |
Effect of M1- and M2-muscarinic drugs on striatal dopamine release and metabolism: an in vivo microdialysis study comparing normal and 6-hydroxydopamine-lesioned rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Atropine; Carbachol; Corpus Striatum; Diamines; Dopamine; Homovanillic Acid; Male; Microdialysis; Oxidopamine; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Reference Values | 1993 |
Asymmetrical orientation to edges of an openfield: modulation by striatal dopamine and relationship to motor asymmetries in the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Apomorphine; Dopamine; Exploratory Behavior; Functional Laterality; Male; Motor Activity; Neostriatum; Orientation; Oxidopamine; Rats; Rats, Sprague-Dawley; Rotation; Stereotyped Behavior | 1994 |
L-3,4-dihydroxyphenylalanine-induced dopamine release in the striatum of intact and 6-hydroxydopamine-treated rats: differential effects of monoamine oxidase A and B inhibitors.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Clorgyline; Corpus Striatum; Dopamine; Levodopa; Male; Monoamine Oxidase Inhibitors; Nerve Endings; Oxidopamine; Picolinic Acids; Rats; Rats, Sprague-Dawley; Selegiline | 1994 |
Clearance of exogenous dopamine in rat dorsal striatum and nucleus accumbens: role of metabolism and effects of locally applied uptake inhibitors.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Catechol O-Methyltransferase; Cocaine; Corpus Striatum; Deoxyepinephrine; Dopamine; Electrochemistry; Kinetics; Male; Microinjections; Nomifensine; Nucleus Accumbens; Oxidopamine; Prosencephalon; Rats; Rats, Sprague-Dawley; Time Factors | 1993 |
Impact of L-dopa on striatal acetylcholine release: effects of 6-hydroxydopamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcholine; Animals; Corpus Striatum; Dopamine; Extracellular Space; Levodopa; Male; Neurons; Nomifensine; Oxidopamine; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2 | 1993 |
Dopaminergic functional supersensitivity: effects of chronic L-dopa and carbidopa treatment in an animal model of Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biopterins; Brain Diseases; Carbidopa; Corpus Striatum; Cyclic AMP; Disease Models, Animal; Dopamine; Dopamine D2 Receptor Antagonists; Homovanillic Acid; Levodopa; Male; Oxidopamine; Parkinson Disease; Rats; Rats, Inbred F344; Receptors, Dopamine D1; Receptors, Dopamine D2; Sensitivity and Specificity; Substantia Nigra; Time Factors | 1993 |
The role of nucleus accumbens dopamine in responding on a continuous reinforcement operant schedule: a neurochemical and behavioral study.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Chromatography, High Pressure Liquid; Conditioning, Operant; Dopamine; Food; Male; Microdialysis; Nucleus Accumbens; Oxidopamine; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Reinforcement, Psychology | 1993 |
The role of nucleus accumbens dopamine in the neurochemical and behavioral effects of phencyclidine: a microdialysis and behavioral study.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Ataxia; Behavior, Animal; Brain Chemistry; Chromatography, High Pressure Liquid; Dialysis; Dopamine; Homovanillic Acid; Male; Motor Activity; Nucleus Accumbens; Oxidopamine; Phencyclidine; Rats; Rats, Sprague-Dawley; Social Behavior; Stereotyped Behavior; Sympathectomy, Chemical | 1993 |
Adrenocorticotropin/alpha-melanocyte-stimulating hormone (ACTH/MSH)-like peptides modulate adenylate cyclase activity in rat brain slices: evidence for an ACTH/MSH receptor-coupled mechanism.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 3,4-Dihydroxyphenylacetic Acid; Adenylyl Cyclases; Adrenocorticotropic Hormone; alpha-MSH; Animals; Brain; Chromatography, High Pressure Liquid; Colforsin; Cyclic AMP; Desipramine; Dopamine; Dose-Response Relationship, Drug; Ergolines; In Vitro Techniques; Kinetics; Male; Organ Specificity; Oxidopamine; Quinpirole; Rats; Rats, Wistar; Receptors, Corticotropin; Receptors, Pituitary Hormone; Sulpiride | 1993 |
Involvement of D2 dopaminergic receptors in the emotional and motivational responses induced by injection of CCK-8 in the posterior part of the rat nucleus accumbens.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Dopamine; Emotions; Exploratory Behavior; Homovanillic Acid; Injections; Male; Motivation; Nucleus Accumbens; Oxidopamine; Rats; Rats, Wistar; Receptors, Dopamine D2; Sincalide; Tegmentum Mesencephali | 1993 |
A neurochemical and behavioral investigation of the involvement of nucleus accumbens dopamine in instrumental avoidance.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Avoidance Learning; Chromatography, High Pressure Liquid; Corpus Striatum; Dialysis; Dopamine; Electroshock; Frontal Lobe; Homovanillic Acid; Male; Nucleus Accumbens; Oxidopamine; Rats; Rats, Sprague-Dawley; Time Factors | 1993 |
Chronic effects of single intrastriatal injections of 6-hydroxydopamine or 1-methyl-4-phenylpyridinium studied by microdialysis in freely moving rats.
Topics: 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Animals; Dopamine; Dopamine Agents; Extracellular Space; Homovanillic Acid; Immunohistochemistry; Injections; Male; Microdialysis; Neostriatum; Oxidopamine; Rats; Rats, Sprague-Dawley; Substantia Nigra; Sympatholytics | 1995 |
Neurokinin-3 receptors modulate dopamine cell function and alter the effects of 6-hydroxydopamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Autoradiography; Dopamine; Gene Expression; In Situ Hybridization; Male; Mesencephalon; Oxidopamine; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-3; Time Factors | 1995 |
Characterization and transplantation of two neuronal cell lines with dopaminergic properties.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adenylyl Cyclases; Animals; Bucladesine; Butyrates; Butyric Acid; Carrier Proteins; Cell Differentiation; Cell Line, Transformed; Cell Transplantation; Clone Cells; Cyclic AMP; Dopamine; Dopamine Plasma Membrane Transport Proteins; Intermediate Filament Proteins; Isoenzymes; Kinetics; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mesencephalon; Methamphetamine; Mice; Nerve Tissue Proteins; Nestin; Neuroblastoma; Neurons; Oxidopamine; Phosphopyruvate Hydratase; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-delta; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Stereotyped Behavior; Tyrosine 3-Monooxygenase | 1996 |
Catecholamines enhance dihydrolipoamide dehydrogenase inactivation by the copper Fenton system. Enzyme protection by copper chelators.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Binding Sites; Captopril; Catecholamines; Catechols; Cattle; Chelating Agents; Copper; Cysteine; Dihydrolipoamide Dehydrogenase; Dopamine; Epinephrine; Hydrogen Peroxide; Hydroxyl Radical; Iron; Kinetics; Mammals; Norepinephrine; Oxidation-Reduction; Oxidopamine; Penicillamine | 1996 |
The yohimbine-induced anticonflict effect in the rat, Part II. Neurochemical findings.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Behavior, Animal; Cerebral Cortex; Chlorides; Conflict, Psychological; Dihydroxyphenylalanine; Enzyme Inhibitors; gamma-Aminobutyric Acid; Hippocampus; Hydrazines; Hydroxyindoleacetic Acid; Male; Norepinephrine; Oxidopamine; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Reserpine; Serotonin; Yohimbine | 1995 |
A novel nonneuronal catecholaminergic system: exocrine pancreas synthesizes and releases dopamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antibodies; Base Sequence; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; DNA Primers; Dopamine; Immunohistochemistry; In Situ Hybridization; Male; Membrane Glycoproteins; Membrane Transport Proteins; Molecular Sequence Data; Neuropeptides; Oxidopamine; Pancreas; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; RNA Probes; RNA, Messenger; Sympathectomy, Chemical; Transcription, Genetic; Tyrosine 3-Monooxygenase; Vesicular Biogenic Amine Transport Proteins | 1996 |
Modulatory role of dopamine on excitatory amino acid receptors.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cerebral Cortex; Dizocilpine Maleate; Dopamine; Dopamine D2 Receptor Antagonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Guanylyl Imidodiphosphate; Male; Oxidopamine; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Amino Acid; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate; Sympatholytics | 1996 |
Effect of 6-hydroxydopamine lesions of the medial prefrontal cortex on intravenous cocaine self-administration under a progressive ratio schedule of reinforcement.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Adrenergic Uptake Inhibitors; Animals; Blood Pressure; Chromatography, High Pressure Liquid; Cocaine; Conditioning, Operant; Desipramine; Dopamine; Dopamine Uptake Inhibitors; Injections, Intravenous; Male; Oxidopamine; Prefrontal Cortex; Rats; Rats, Wistar; Reinforcement Schedule; Self Administration | 1996 |
Effect of subcutaneous administration of levodopa ethyl ester, a soluble prodrug of levodopa, on dopamine metabolism in rodent striatum: implication for treatment of Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antiparkinson Agents; Behavior, Animal; Dopamine; Injections, Subcutaneous; Levodopa; Male; Mice; Mice, Inbred C57BL; Neostriatum; Oxidopamine; Prodrugs; Rats; Stereotyped Behavior; Sympatholytics | 1996 |
Modulation of neurotransmitter release by cholecystokinin in the neostriatum and substantia nigra of the rat: regional and receptor specificity.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Aspartic Acid; Cholecystokinin; Dopamine; Dynorphins; Endorphins; gamma-Aminobutyric Acid; Glutamic Acid; Homovanillic Acid; Kinetics; Male; Neostriatum; Neurons; Neurotransmitter Agents; Organ Specificity; Oxidopamine; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Substantia Nigra; Time Factors | 1996 |
Cyclosporin A attenuates degeneration of dopaminergic neurons induced by 6-hydroxydopamine in the mouse brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cell Death; Cyclosporine; Dopamine; Homovanillic Acid; Immunosuppressive Agents; Male; Mice; Mice, Inbred ICR; Neostriatum; Neurons; Neuroprotective Agents; Oxidopamine; Substantia Nigra | 1996 |
Subacute toluene exposure increases DA dysfunction in the 6-OH dopamine lesioned nigrostriatal dopaminergic system of the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Drug Administration Schedule; Drug Synergism; Male; Neurotoxins; Norepinephrine; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Substantia Nigra; Toluene | 1996 |
Differential sensitivity of dopamine release and clearance to 6-hydroxydopamine lesioning in rat striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Caudate Nucleus; Corpus Striatum; Dopamine; Dopamine Uptake Inhibitors; Electrodes, Implanted; Homovanillic Acid; Nomifensine; Oxidopamine; Potassium Chloride; Rats; Rats, Sprague-Dawley; Sympatholytics | 1996 |
Dynamic regulation of striatal dopaminergic grafts during locomotor activity.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cell Transplantation; Corpus Striatum; Dopamine; Extracellular Space; Homovanillic Acid; Methamphetamine; Microdialysis; Motor Activity; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Wistar; Rotation; Stereotyped Behavior; Substantia Nigra; Time Factors | 1996 |
Dopamine differentiation factors produce partial motor recovery in 6-hydroxydopamine lesioned rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cell Differentiation; Dopamine; Fibroblast Growth Factor 1; Growth Substances; Humans; Motor Activity; Muscles; Neurotoxins; Oxidopamine; Rats; Rats, Sprague-Dawley; Rotation | 1995 |
L-DOPA modulation of corpus striatal dopamine and dihydroxyphenylacetic acid output from intact and 6-OHDA lesioned rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antiparkinson Agents; Corpus Striatum; Dopamine; Levodopa; Male; Oxidopamine; Rats; Rats, Sprague-Dawley; Substantia Nigra; Sympathectomy, Chemical | 1996 |
Effects of dopamine depletion in the medial prefrontal cortex on the stress-induced increase in extracellular dopamine in the nucleus accumbens core and shell.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Disease Models, Animal; Dopamine; Dopamine Agents; Fluorescent Dyes; Locomotion; Male; Microdialysis; Neurons; Nucleus Accumbens; Oxidopamine; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Schizophrenia; Stilbamidines; Stress, Physiological; Sympatholytics | 1997 |
Morphological and biochemical adaptations to unilateral dopamine denervation of the neostriatum in newborn rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Animals, Newborn; Basal Ganglia; Denervation; Dopamine; Functional Laterality; Globus Pallidus; Hydroxyindoleacetic Acid; Immunohistochemistry; Male; Motor Activity; Neostriatum; Oxidopamine; Pargyline; Rats; Rats, Sprague-Dawley; Serotonin; Substantia Nigra; Tyrosine 3-Monooxygenase | 1997 |
Behavioral and neurochemical recovery from partial 6-hydroxydopamine lesions of the substantia nigra is blocked by daily treatment with D1/D5, but not D2, dopamine receptor antagonists.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Benzazepines; Dopamine; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Homovanillic Acid; Male; Microdialysis; Oxidopamine; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D5; Substantia Nigra; Sympatholytics | 1997 |
Modulatory role of catecholamines in the transsynaptic expression of c-fos in the rat medial prefrontal cortex induced by disinhibition of the mediodorsal thalamus: a study employing microdialysis and immunohistochemistry.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Bicuculline; Dopamine; GABA-A Receptor Antagonists; Genes, fos; Hydroxyindoleacetic Acid; Immunohistochemistry; Infusions, Parenteral; Male; Microdialysis; Motor Activity; Multivariate Analysis; Norepinephrine; Oxidopamine; Prefrontal Cortex; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Serotonin; Stereotyped Behavior; Thalamic Nuclei; Thalamus | 1997 |
Intracerebroventricular glial cell line-derived neurotrophic factor improves motor function and supports nigrostriatal dopamine neurons in bilaterally 6-hydroxydopamine lesioned rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Chromatography, High Pressure Liquid; Disease Models, Animal; Dopamine; Epinephrine; Frontal Lobe; Glial Cell Line-Derived Neurotrophic Factor; Hydroxyindoleacetic Acid; Immunohistochemistry; Injections, Intraventricular; Male; Motor Activity; Nerve Growth Factors; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Oxidopamine; Parkinson Disease; Rats; Rats, Inbred F344; Serotonin; Substantia Nigra; Sympatholytics; Ventral Tegmental Area | 1997 |
Regulation of dopamine D1 and D2 receptors on striatal acetylcholine release in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcholine; Analysis of Variance; Animals; Corpus Striatum; Dopamine; Dopamine Agonists; Dopamine Antagonists; Male; Microdialysis; Neurotoxins; Oxidopamine; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D2; Substantia Nigra | 1997 |
Cyclosporin A attenuates the decrease in tyrosine hydroxylase immunoreactivity in nigrostriatal dopaminergic neurons and in striatal dopamine content in rats with intrastriatal injection of 6-hydroxydopamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Cyclosporine; Dopamine; Homovanillic Acid; Immunosuppressive Agents; Injections; Male; Neurons; Oxidopamine; Rats; Rats, Sprague-Dawley; Substantia Nigra; Tyrosine 3-Monooxygenase | 1997 |
GDNF protection against 6-OHDA: time dependence and requirement for protein synthesis.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cell Survival; Chromatography, High Pressure Liquid; Cycloheximide; Dopamine; Glial Cell Line-Derived Neurotrophic Factor; Injections, Intraventricular; Male; Nerve Growth Factors; Nerve Tissue Proteins; Neuroprotective Agents; Oxidopamine; Protein Biosynthesis; Protein Synthesis Inhibitors; Rats; Rats, Inbred F344; Substantia Nigra; Ventral Tegmental Area | 1997 |
Growth/differentiation factor 5 protects nigrostriatal dopaminergic neurones in a rat model of Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Bone Morphogenetic Proteins; Corpus Striatum; Dopamine; Growth Differentiation Factor 5; Growth Substances; Homovanillic Acid; Injections, Intraventricular; Neuroprotective Agents; Oxidopamine; Parkinson Disease, Secondary; Rats; Recombinant Proteins; Substantia Nigra; Transforming Growth Factor beta | 1997 |
Loss of dopamine terminals in the medial prefrontal cortex increased the ratio of DOPAC to DA in tissue of the nucleus accumbens shell: role of stress.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Dopamine; Immunohistochemistry; Male; Neostriatum; Nerve Endings; Neurotoxins; Nucleus Accumbens; Oxidopamine; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Stress, Physiological; Tyrosine 3-Monooxygenase | 1997 |
Estrogen decreases corpus striatal neurotoxicity in response to 6-hydroxydopamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Disease Models, Animal; Dopamine; Estradiol; Female; Neurotoxins; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley | 1997 |
Lesion of nigrostriatal neurons by 6-hydroxydopamine induces changes in rat brain glutathione-S-transferase.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Enzyme Induction; Glutathione Transferase; Homovanillic Acid; Male; Neurons; Neurotoxins; Oxidopamine; Rats; Rats, Wistar; Substantia Nigra | 1997 |
Adenoviral vector-mediated GDNF gene therapy in a rodent lesion model of late stage Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adenoviridae; Animals; Apomorphine; Behavior, Animal; Disease Models, Animal; Dopamine; Dopamine Agonists; Enzyme-Linked Immunosorbent Assay; Female; Genetic Therapy; Genetic Vectors; Glial Cell Line-Derived Neurotrophic Factor; Humans; Nerve Growth Factors; Nerve Regeneration; Nerve Tissue Proteins; Neuroprotective Agents; Oxidopamine; Parkinson Disease; Rats; Rats, Wistar; Substantia Nigra; Sympatholytics | 1997 |
Distribution of zinc in the substantia nigra of rats treated with 6-hydroxydopamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Animals; Autoradiography; Blood-Brain Barrier; Chlorides; Corpus Striatum; Gliosis; Homovanillic Acid; In Vitro Techniques; Injections, Intravenous; Male; Nerve Degeneration; Oxidopamine; Quaternary Ammonium Compounds; Radionuclide Imaging; Rats; Rats, Wistar; Substantia Nigra; Technetium Compounds; Time Factors; Zinc; Zinc Compounds; Zinc Radioisotopes | 1998 |
Dopamine metabolism in the striatum of hemiparkinsonian model rats with dopaminergic grafts.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Autoradiography; Brain Tissue Transplantation; Carrier Proteins; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Female; Fetal Tissue Transplantation; Functional Laterality; Haloperidol; Homovanillic Acid; Kinetics; Levodopa; Mazindol; Membrane Glycoproteins; Membrane Transport Proteins; Mesencephalon; Methamphetamine; Microdialysis; Motor Activity; Nerve Tissue Proteins; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Wistar; Rotation; Tritium; Tyrosine 3-Monooxygenase | 1998 |
Neurturin exerts potent actions on survival and function of midbrain dopaminergic neurons.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cell Survival; Cells, Cultured; Corpus Striatum; Disease Models, Animal; Dopamine; Gene Expression Regulation, Developmental; Glial Cell Line-Derived Neurotrophic Factor; Mice; Nerve Growth Factors; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Neurturin; Nucleus Accumbens; Oxidopamine; Parkinson Disease, Secondary; RNA, Messenger; Substantia Nigra; Sympatholytics | 1998 |
Progressive accumbens degeneration after neonatal striatal 6-hydroxydopamine in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Animals, Newborn; Caudate Nucleus; Chromatography, High Pressure Liquid; Disease Progression; Dopamine; Homovanillic Acid; Nerve Degeneration; Neurotoxins; Nucleus Accumbens; Oxidopamine; Parkinson Disease, Secondary; Putamen; Rats; Rats, Sprague-Dawley | 1998 |
Differential regulation of dopamine release by N-methyl-D-aspartate receptors in rat striatum after partial and extreme lesions of the nigro-striatal pathway.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Corpus Striatum; Denervation; Dizocilpine Maleate; Dopamine; Excitatory Amino Acid Antagonists; Extracellular Space; Male; Microdialysis; Neural Pathways; Oxidopamine; Potassium; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Substantia Nigra; Sympatholytics | 1998 |
Effect of trihexyphenidyl, a non-selective antimuscarinic drug, on decarboxylation of L-dopa in hemi-Parkinson rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antiparkinson Agents; Biotransformation; Corpus Striatum; Decarboxylation; Dopamine; Drug Interactions; Homovanillic Acid; Levodopa; Male; Microdialysis; Muscarinic Antagonists; Oxidopamine; Parkinson Disease; Rats; Rats, Wistar; Substantia Nigra; Trihexyphenidyl | 1998 |
Long-term protection of the rat nigrostriatal dopaminergic system by glial cell line-derived neurotrophic factor against 6-hydroxydopamine in vivo.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Corpus Striatum; Dopamine; Glial Cell Line-Derived Neurotrophic Factor; Homovanillic Acid; Male; Nerve Growth Factors; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Oxidopamine; Rats; Rats, Sprague-Dawley; Substantia Nigra; Sympatholytics; Time Factors; Tomography, Emission-Computed; Tyrosine 3-Monooxygenase | 1998 |
The role of nigrostriatal dopamine in metabotropic glutamate agonist-induced rotation.
Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Methyltyrosine; Aminobutyrates; Animals; Corpus Striatum; Deoxyglucose; Desipramine; Dominance, Cerebral; Dopamine; Excitatory Amino Acid Agonists; Gene Expression Regulation; Genes, fos; Glycine; Indans; Male; Motor Activity; Nerve Tissue Proteins; Oxidopamine; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Reserpine; Resorcinols; Substantia Nigra; Superior Colliculi | 1998 |
Methamphetamine-induced modification of dopamine metabolism in cultured striatal astrocytes.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Animals, Newborn; Astrocytes; Cells, Cultured; Corpus Striatum; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Methamphetamine; Monoamine Oxidase Inhibitors; Oxidopamine; Rats; Rats, Sprague-Dawley | 1998 |
Effects of pergolide treatment on in vivo hydroxyl free radical formation during infusion of 6-hydroxydopamine in rat striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antiparkinson Agents; Chromatography, High Pressure Liquid; Dopamine; Free Radical Scavengers; Hydroxyl Radical; Injections; Male; Neostriatum; Oxidopamine; Pergolide; Rats; Rats, Sprague-Dawley; Sympatholytics | 1998 |
Hydroxyl radical production in the substantia nigra after 6-hydroxydopamine and hypoxia-reoxygenation.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Dopamine; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; Hypoxia, Brain; Male; Neurotoxins; Oxidopamine; Oxygen; Partial Pressure; Rats; Rats, Sprague-Dawley; Salicylic Acid; Substantia Nigra | 1998 |
Catecholaminergic mechanisms-mediated hypothermia induced by magnolol in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; alpha-Methyltyrosine; Animals; Anti-Anxiety Agents; Biphenyl Compounds; Body Temperature; Catecholamines; Colon; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epinephrine; Homovanillic Acid; Hypothalamus; Hypothermia, Induced; Injections, Intraperitoneal; Injections, Intraventricular; Levodopa; Lignans; Male; Norepinephrine; Oxidopamine; Rats; Rats, Sprague-Dawley | 1998 |
Melatonin increases striatal dopaminergic function in 6-OHDA-lesioned rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antioxidants; Corpus Striatum; Dopamine; Male; Malondialdehyde; Melatonin; Oxidopamine; Rats; Tyrosine 3-Monooxygenase | 1998 |
Role of serotonergic neurons in L-DOPA-derived extracellular dopamine in the striatum of 6-OHDA-lesioned rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; 5,7-Dihydroxytryptamine; Animals; Apomorphine; Corpus Striatum; Dopamine; Dopamine Agents; Extracellular Space; Levodopa; Male; Microdialysis; Neurons; Oxidopamine; Rats; Rats, Wistar; Rotation; Serotonin; Serotonin Agents; Stereotyped Behavior | 1999 |
Pergolide potentiates L-DOPA-induced dopamine release in rat striatum after lesioning with 6-hydroxydopamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Disease Models, Animal; Dopamine; Dopamine Agonists; Drug Synergism; Homovanillic Acid; Hydroxyindoleacetic Acid; Levodopa; Male; Microdialysis; Motor Activity; Neostriatum; Neurons; Oxidopamine; Parkinson Disease, Secondary; Pergolide; Rats; Rats, Wistar | 1999 |
Treating neonatal rats with 6-hydroxydopamine induced an increase in voluntary alcohol consumption.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Drinking; Animals; Animals, Newborn; Biogenic Monoamines; Brain; Dopamine; Hydroxyindoleacetic Acid; Male; Nucleus Accumbens; Oxidopamine; Rats; Rats, Wistar; Serotonin; Sympatholytics | 1999 |
Regional metabolic changes in the pedunculopontine nucleus of unilateral 6-hydroxydopamine Parkinson's model rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antimetabolites; Basal Ganglia Diseases; Cerebral Cortex; Deoxyglucose; Disease Models, Animal; Dopamine; Energy Metabolism; Glucose; Male; Oxidopamine; Parkinson Disease, Secondary; Pons; Rats; Rats, Sprague-Dawley; Sympatholytics | 1999 |
Dopamine depletion in the medial prefrontal cortex induces sensitized-like behavioral and neurochemical responses to cocaine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Brain Chemistry; Chromatography, High Pressure Liquid; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Tolerance; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Microdialysis; Nucleus Accumbens; Oxidopamine; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Sympatholytics; Synaptic Transmission | 1999 |
Incomplete nigrostriatal dopaminergic cell loss and partial reductions in striatal dopamine produce akinesia, rigidity, tremor and cognitive deficits in middle-aged rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Age Factors; Animals; Brain Mapping; Corpus Striatum; Dementia; Dopamine; Dyskinesia, Drug-Induced; Male; Maze Learning; Mental Recall; Motor Skills; Muscle Rigidity; Nerve Degeneration; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Substantia Nigra; Tremor | 1999 |
Serotonin 2A receptor mRNA levels in the neonatal dopamine-depleted rat striatum remain upregulated following suppression of serotonin hyperinnervation.
Topics: 3,4-Dihydroxyphenylacetic Acid; 5,7-Dihydroxytryptamine; Animals; Animals, Newborn; Corpus Striatum; Depression, Chemical; Dopamine; Injections, Intraventricular; Neurotoxins; Oxidopamine; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; RNA, Messenger; Serotonin Agents; Up-Regulation | 1999 |
Comparison of effects of hypotension and handling stress on the release of noradrenaline and dopamine in the locus coeruleus and medial prefrontal cortex of the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Anesthesia; Animals; Antihypertensive Agents; Dopamine; Handling, Psychological; Hypotension; Locus Coeruleus; Male; Microdialysis; Nitroprusside; Norepinephrine; Oxidopamine; Prefrontal Cortex; Rats; Rats, Wistar; Stress, Psychological | 1999 |
Effects of partial dopamine loss in the medial prefrontal cortex on local baseline and stress-evoked extracellular dopamine concentrations.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Axons; Dopamine; Dopamine beta-Hydroxylase; Extracellular Space; Homovanillic Acid; Immunohistochemistry; Male; Microdialysis; Oxidopamine; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Stress, Psychological; Sympatholytics; Tyrosine 3-Monooxygenase | 1999 |
Subchronic toluene exposure in low concentrations produces signs of reduced dysfunction in the 6-hydroxydopamine lesioned nigrostriatal dopaminergic system of the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Behavior, Animal; Denervation; Dopamine; Injections, Intraventricular; Male; Motor Activity; Neostriatum; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Substantia Nigra; Toluene; Tyrosine 3-Monooxygenase | 1999 |
EPC-K1, a hydroxyl radical scavenger, prevents 6-hydroxydopamine-induced dopamine depletion in the mouse striatum by up-regulation of catalase activity.
Topics: 3,4-Dihydroxyphenylacetic Acid; Administration, Oral; Animals; Ascorbic Acid; Catalase; Cerebral Ventricles; Corpus Striatum; Dopamine; Free Radical Scavengers; Glutathione; Homovanillic Acid; Hydroxyl Radical; Injections, Intraventricular; Male; Malondialdehyde; Mice; Mice, Inbred ICR; Oxidopamine; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Vitamin E | 1999 |
The effect of a subchronic post-lesion treatment with (-)-deprenyl on the sensitivity of 6-OHDA-lesioned rats to apomorphine and d-amphetamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Amphetamine; Animals; Antiparkinson Agents; Apomorphine; Behavior, Animal; Corpus Striatum; Dopamine; Dopamine Agents; Homovanillic Acid; Male; Medial Forebrain Bundle; Oxidopamine; Rats; Rats, Sprague-Dawley; Selegiline | 1999 |
Nicotine stimulation of extracellular glutamate levels in the nucleus accumbens: neuropharmacological characterization.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amino Acid Transport System X-AG; Animals; Aspartic Acid; ATP-Binding Cassette Transporters; Biological Transport; Denervation; Dicarboxylic Acids; Dopamine; Extracellular Space; Glutamic Acid; Haloperidol; Kainic Acid; Kinetics; Male; Mecamylamine; Microdialysis; Neurotransmitter Uptake Inhibitors; Nicotine; Nucleus Accumbens; Oxidopamine; Pyrrolidines; Rats; Rats, Sprague-Dawley | 2000 |
Reserpine pretreatment prevents increases in extracellular striatal dopamine following L-DOPA administration in rats with nigrostriatal denervation.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Denervation; Dopamine; Extracellular Space; Homovanillic Acid; Levodopa; Male; Oxidopamine; Rats; Rats, Wistar; Reserpine; Substantia Nigra | 2000 |
The pivotal role of iron in NF-kappa B activation and nigrostriatal dopaminergic neurodegeneration. Prospects for neuroprotection in Parkinson's disease with iron chelators.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Animals; Antiparkinson Agents; Apomorphine; Corpus Striatum; Dopamine; Dopamine Agents; Ferritins; Iron; Lipid Peroxidation; Mice; Nerve Degeneration; NF-kappa B; Oxidopamine; Parkinsonian Disorders; PC12 Cells; Rats; Tyrosine 3-Monooxygenase | 1999 |
Time-dependent striatal dopamine depletion after injection of 6-hydroxydopamine in the rat. Comparison of single bilateral and double bilateral lesions.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Disease Models, Animal; Dopamine; Functional Laterality; Injections; Male; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Wistar | 1999 |
Stimulated serotonin release from hyperinnervated terminals subsequent to neonatal dopamine depletion regulates striatal tachykinin, but not enkephalin gene expression.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Animals, Newborn; Cerebral Ventricles; Corpus Striatum; Desipramine; Dopamine; Enkephalins; Gene Expression Regulation; Hydroxyindoleacetic Acid; Injections, Intraventricular; Oxidopamine; p-Chloroamphetamine; Protein Precursors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Serotonin; Tachykinins; Transcription, Genetic | 2000 |
DOPA, dopamine, and DOPAC concentrations in the rat gastrointestinal tract decrease during fasting.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenalectomy; Animals; Chromatography, High Pressure Liquid; Digestive System; Dihydroxyphenylalanine; Dopamine; Epinephrine; Fasting; Gastric Mucosa; Kidney; Male; Muscle, Skeletal; Myocardium; Norepinephrine; Organ Specificity; Oxidopamine; Rats; Rats, Wistar; Sympathectomy, Chemical | 2000 |
A common signaling pathway for striatal NMDA and adenosine A2a receptors: implications for the treatment of Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Corpus Striatum; Cyclic AMP; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; In Vitro Techniques; Male; N-Methylaspartate; Neuroprotective Agents; Oxidopamine; Parkinson Disease, Secondary; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Receptors, N-Methyl-D-Aspartate; Receptors, Purinergic P1; Signal Transduction | 2000 |
Estimation of striatal dopamine spillover and metabolism in vivo.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Homovanillic Acid; Injections; Male; Medial Forebrain Bundle; Microdialysis; Osmolar Concentration; Oxidopamine; Rats; Rats, Sprague-Dawley; Sucrose | 2000 |
The influence of pallidal deep brain stimulation on striatal dopaminergic metabolism in the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Denervation; Dopamine; Electric Stimulation Therapy; Globus Pallidus; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Neostriatum; Neural Pathways; Oxidopamine; Parkinson Disease; Rats; Rats, Wistar | 2000 |
The central aromatic amino acid DOPA decarboxylase inhibitor, NSD-1015, does not inhibit L-DOPA-induced circling in unilateral 6-OHDA-lesioned-rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Behavior, Animal; Biogenic Monoamines; Brain; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Dopamine Agents; Dopamine Antagonists; Drug Combinations; Enzyme Inhibitors; Haloperidol; Homovanillic Acid; Hydrazines; Levodopa; Male; Medial Forebrain Bundle; Oxidopamine; Rats; Rats, Wistar; Stereotyped Behavior; Tyrosine | 2001 |
Regulation of EphB1 expression by dopamine signaling.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Animals, Newborn; Cerebral Cortex; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Dopamine; Dopamine Uptake Inhibitors; Ephrin-B1; Female; Gene Expression; Homovanillic Acid; In Situ Hybridization; Membrane Proteins; Mice; Mice, Inbred Strains; Nerve Degeneration; Oxidopamine; Pregnancy; RNA, Messenger; Signal Transduction; Substantia Nigra; Sympatholytics | 2000 |
Nicotine prevents striatal dopamine loss produced by 6-hydroxydopamine lesion in the substantia nigra.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Chlorisondamine; Corpus Striatum; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Drug Administration Schedule; Injections, Subcutaneous; Male; Neuroprotective Agents; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Substantia Nigra | 2001 |
Catecholamines and their metabolites in the brain and urine of rats with experimental Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Catecholamines; Dihydroxyphenylalanine; Dopamine; Epinephrine; Homovanillic Acid; Male; Methoxyhydroxyphenylglycol; Norepinephrine; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Wistar | 2000 |
High frequency stimulation of the subthalamic nucleus increases the extracellular contents of striatal dopamine in normal and partially dopaminergic denervated rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Denervation; Dopamine; Electric Stimulation; Extracellular Space; Male; Oxidopamine; Rats; Rats, Sprague-Dawley; Reference Values; Subthalamic Nucleus; Tyrosine 3-Monooxygenase | 2001 |
Increased extracellular DA and normal evoked DA release in the rat striatum after a partial lesion of the substantia nigra.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Autoradiography; Carrier Proteins; Caudate Nucleus; Cell Count; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Electric Stimulation; Electrodes, Implanted; Extracellular Space; Homovanillic Acid; Male; Medial Forebrain Bundle; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Oxidopamine; Putamen; Rats; Rats, Sprague-Dawley; Substantia Nigra; Tyrosine 3-Monooxygenase | 2001 |
Protective effect of quinacrine on striatal dopamine levels in 6-OHDA and MPTP models of Parkinsonism in rodents.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Dopamine; Enzyme Inhibitors; Glutathione; Homovanillic Acid; Male; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Oxidative Stress; Oxidopamine; Parkinsonian Disorders; Phospholipases; Quinacrine; Rats; Rats, Wistar; Sympatholytics | 2001 |
Adrenergic hyperactivity and metanephrine excess in the nucleus accumbens after prefrontocortical dopamine depletion.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Anxiety; Behavior, Animal; Darkness; Dopamine; Epinephrine; Light; Male; Metanephrine; Microinjections; Motor Activity; Norepinephrine; Nucleus Accumbens; Oxidopamine; Prefrontal Cortex; Rats; Rats, Wistar; Spatial Behavior; Stereotypic Movement Disorder; Vanilmandelic Acid | 2001 |
Complex analysis of efficiency of transplantation of embryonic nerve tissue to rats with hemiparkinsonism.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Tissue Transplantation; Dopamine; Fetal Tissue Transplantation; Male; Mesencephalon; Nerve Regeneration; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Wistar | 2000 |
Neuroprotective effects of GDNF against 6-OHDA in young and aged rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Cell Survival; Dopamine; Glial Cell Line-Derived Neurotrophic Factor; Male; Nerve Degeneration; Nerve Growth Factors; Nerve Tissue Proteins; Neuroprotective Agents; Oxidopamine; Rats; Rats, Inbred BN; Rats, Inbred F344; Substantia Nigra; Sympatholytics; Tyrosine 3-Monooxygenase | 2001 |
Striatal dopaminergic metabolism is increased by deep brain stimulation of the subthalamic nucleus in 6-hydroxydopamine lesioned rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Dopamine; Electric Stimulation Therapy; Extracellular Space; Homovanillic Acid; Male; Microdialysis; Neostriatum; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Wistar; Subthalamic Nucleus; Sympatholytics | 2001 |
Microdialysates of amines and metabolites from core nucleus accumbens of freely moving rats are altered by dizocilpine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benzylamines; Chromatography, High Pressure Liquid; Desipramine; Dizocilpine Maleate; Dopamine; Excitatory Amino Acid Antagonists; Male; Microdialysis; Motor Activity; Neuroprotective Agents; Neurotransmitter Agents; Norepinephrine; Nucleus Accumbens; Oxidopamine; Rats; Rats, Wistar; Reserpine; Serotonin | 2001 |
Forced limb-use effects on the behavioral and neurochemical effects of 6-hydroxydopamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Behavior, Animal; Body Temperature; Casts, Surgical; Corpus Striatum; Disease Models, Animal; Dopamine; Forelimb; Homovanillic Acid; Immobilization; Male; Medial Forebrain Bundle; Membrane Glycoproteins; Membrane Transport Proteins; Microinjections; Neural Pathways; Neurons; Neuropeptides; Oxidopamine; Parkinson Disease; Parkinson Disease, Secondary; Rats; Rats, Long-Evans; Substantia Nigra; Vesicular Biogenic Amine Transport Proteins; Vesicular Monoamine Transport Proteins | 2001 |
The role of dopamine receptors in regulating the size of axonal arbors.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Axons; Carrier Proteins; Cell Count; Corpus Striatum; Dopamine; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dopamine Plasma Membrane Transport Proteins; Heterozygote; Homozygote; Immunohistochemistry; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Inbred Strains; Mice, Knockout; Nerve Tissue Proteins; Neural Pathways; Neurons; Oxidopamine; Presynaptic Terminals; Receptors, Dopamine D1; Receptors, Dopamine D2; Substantia Nigra | 2001 |
Serotonin 2A receptor regulation of striatal neuropeptide gene expression is selective for tachykinin, but not enkephalin neurons following dopamine depletion.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamines; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Enkephalins; Gene Expression Regulation; Hydroxyindoleacetic Acid; In Situ Hybridization; Ketanserin; Male; Neurons; Oxidopamine; Protein Precursors; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sympatholytics; Tachykinins; Transcription, Genetic | 2001 |
Neonatal dopamine depletion reveals a synergistic mechanism of mRNA regulation that is mediated by dopamine(D1) and serotonin(2) receptors and is targeted to tachykinin neurons of the dorsomedial striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Animals, Newborn; Dopamine; Dopamine Agonists; Dopamine Antagonists; Drug Synergism; Enkephalins; Gene Expression Regulation, Developmental; Male; Movement Disorders; Neostriatum; Neurons; Oxidopamine; Protein Precursors; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Serotonin; RNA, Messenger; Serotonin Antagonists; Serotonin Receptor Agonists; Tachykinins | 2001 |
Dopamine mediates striatal malonate toxicity via dopamine transporter-dependent generation of reactive oxygen species and D2 but not D1 receptor activation.
Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Methyltyrosine; Animals; Benzazepines; Brain Diseases; Carbidopa; Carrier Proteins; Corpus Striatum; Dizocilpine Maleate; Dopamine; Dopamine D2 Receptor Antagonists; Dopamine Plasma Membrane Transport Proteins; Enzyme Inhibitors; Homovanillic Acid; Levodopa; Male; Malonates; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Neuropeptides; Oxidopamine; Rats; Rats, Wistar; Reactive Oxygen Species; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate; Reserpine; Succinate Dehydrogenase; Sulpiride; Vesicular Biogenic Amine Transport Proteins; Vesicular Monoamine Transport Proteins | 2001 |
Role of nitric oxide in a progressive neurodegeneration model of Parkinson's disease in the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Animals; Corpus Striatum; Disease Models, Animal; Disease Progression; Dopamine; Enzyme Inhibitors; Homovanillic Acid; Male; Motor Activity; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidopamine; Parkinson Disease; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley | 2001 |
Persistent behavioral sensitization to chronic L-DOPA requires A2A adenosine receptors.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adaptation, Physiological; Animals; Autoradiography; Behavior, Animal; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Drug Administration Schedule; Dynorphins; Female; Levodopa; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Knockout; Motor Activity; Nerve Tissue Proteins; Oxidopamine; Parkinson Disease, Secondary; Receptor, Adenosine A2A; Receptors, Purinergic P1; RNA, Messenger; Substantia Nigra | 2002 |
Role of dopaminergic system in core part of nucleus accumbens in hyperlocomotion and rearing induced by MK-801 in rats: a behavioral and in vivo microdialysis study.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Chromatography, High Pressure Liquid; Dizocilpine Maleate; Dopamine; Electrochemistry; Excitatory Amino Acid Antagonists; Extracellular Space; Male; Microdialysis; Motor Activity; Nucleus Accumbens; Oxidopamine; Rats; Rats, Wistar; Serotonin; Stereotaxic Techniques; Sympathectomy, Chemical; Sympatholytics | 2001 |
Melatonin reverses neurochemical alterations induced by 6-OHDA in rat striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Free Radical Scavengers; Homovanillic Acid; Hydroxyindoleacetic Acid; Injections, Intraperitoneal; Male; Melatonin; Microinjections; Oxidopamine; Rats; Rats, Wistar; Serotonin; Sympatholytics | 2002 |
Oxidative stress and dopamine deficiency in a genetic mouse model of Lesch-Nyhan disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aconitate Hydratase; Animals; Cell Death; Disease Models, Animal; Dopamine; Female; Free Radical Scavengers; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Lesch-Nyhan Syndrome; Lipid Peroxides; Male; Membrane Proteins; Mice; Mice, Knockout; Mice, Transgenic; Mutation; Neostriatum; Neurons; Oxidative Stress; Oxidopamine; Superoxide Dismutase; Superoxide Dismutase-1 | 2002 |
Deep brain stimulation of subthalamic neurons increases striatal dopamine metabolism and induces contralateral circling in freely moving 6-hydroxydopamine-lesioned rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cell Death; Disease Models, Animal; Dopamine; Electric Stimulation Therapy; Functional Laterality; Male; Neostriatum; Neural Pathways; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Wistar; Rotation; Substantia Nigra; Subthalamic Nucleus; Sympatholytics; Tyrosine 3-Monooxygenase; Up-Regulation | 2002 |
Forced nonuse in unilateral parkinsonian rats exacerbates injury.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Behavior, Animal; Brain Chemistry; Casts, Surgical; Corpus Striatum; Disease Models, Animal; Disease Progression; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Forelimb; Homovanillic Acid; Membrane Glycoproteins; Membrane Transport Proteins; Movement; Nerve Tissue Proteins; Neuropeptides; Oxidopamine; Parkinsonian Disorders; Physical Exertion; Rats; Rats, Long-Evans; Restraint, Physical; Tyrosine 3-Monooxygenase; Vesicular Biogenic Amine Transport Proteins | 2002 |
Locomotor stimulant effects of nornicotine: role of dopamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benzazepines; Dihydroxyphenylalanine; Dopamine; Dopamine Antagonists; Drug Synergism; Male; Motor Activity; Nicotine; Nucleus Accumbens; Oxidopamine; Rats; Rats, Sprague-Dawley; Salicylamides; Stimulation, Chemical; Sympathectomy, Chemical; Sympatholytics | 2002 |
Differences in dopaminergic neuroprotective effects of estrogen during estrous cycle.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Chlorides; Diestrus; Dopamine; Dopamine Plasma Membrane Transport Proteins; Estradiol; Estrogens; Estrous Cycle; Female; Ferric Compounds; Free Radicals; Homovanillic Acid; Injections; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Neuroprotective Agents; Neurotoxins; Oxidopamine; Parkinsonian Disorders; Proestrus; Rats; Rats, Wistar; Substantia Nigra | 2003 |
Neuroprotective effects of prior limb use in 6-hydroxydopamine-treated rats: possible role of GDNF.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Behavior, Animal; Casts, Surgical; Corpus Striatum; Disease Models, Animal; Dopamine; Forelimb; Functional Laterality; Glial Cell Line-Derived Neurotrophic Factor; Immobilization; Male; Medial Forebrain Bundle; Motor Activity; Nerve Growth Factors; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Long-Evans; Rats, Sprague-Dawley | 2003 |
Potentiation of parkinsonian symptoms by depletion of locus coeruleus noradrenaline in 6-hydroxydopamine-induced partial degeneration of substantia nigra in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Animals; Behavior, Animal; Benzylamines; Catalepsy; Disease Models, Animal; Dopamine; Dopamine Antagonists; Drug Interactions; Haloperidol; Hippocampus; Homovanillic Acid; Hypothalamus; Locus Coeruleus; Male; Medial Forebrain Bundle; Nerve Degeneration; Neurotoxins; Norepinephrine; Oxidopamine; Parkinsonian Disorders; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Reaction Time; Serotonin; Substantia Nigra; Thalamus; Tyrosine | 2003 |
Combined intrastriatal dopamine D1 and serotonin 5-HT2 receptor stimulation reveals a mechanism for hyperlocomotion in 6-hydroxydopamine-lesioned rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Benzazepines; Corpus Striatum; Dopamine; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Interactions; Hydroxyindoleacetic Acid; Indophenol; Locomotion; Male; Oxidopamine; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Serotonin, 5-HT2; Serotonin; Serotonin Receptor Agonists; Stereotyped Behavior; Sympatholytics | 2003 |
Effect of glial cell line-derived neurotrophic factor (GDNF) co-transplantation with fetal ventral mesencephalic cells (VMC) on functional restoration in 6-hydroxydopamine (6-OHDA) lesioned rat model of Parkinson's disease: neurobehavioral, neurochemical
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cell Line; Chemotherapy, Adjuvant; Female; Glial Cell Line-Derived Neurotrophic Factor; Locomotion; Mesencephalon; Nerve Growth Factors; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Wistar; Receptors, Dopamine; Recovery of Function; Substantia Nigra; Treatment Outcome | 2003 |
Behavioral and neurochemical effects of noradrenergic depletions with N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine in 6-hydroxydopamine-induced rat model of Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Amphetamine; Analysis of Variance; Animals; Basal Ganglia; Behavior, Animal; Benzylamines; Brain Chemistry; Catalepsy; Disease Models, Animal; Dopamine; Dopamine Agents; Homovanillic Acid; Levodopa; Locus Coeruleus; Male; Motor Activity; Norepinephrine; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Serotonin; Statistics, Nonparametric; Tyrosine | 2004 |
Ironing iron out in Parkinson's disease and other neurodegenerative diseases with iron chelators: a lesson from 6-hydroxydopamine and iron chelators, desferal and VK-28.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Behavior, Animal; Brain; Brocresine; Chromatography, High Pressure Liquid; Deferoxamine; Disease Models, Animal; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Exploratory Behavior; Functional Laterality; Homovanillic Acid; Iron; Iron Chelating Agents; Levodopa; Male; Motor Activity; Neurodegenerative Diseases; Neurotransmitter Agents; Oxidopamine; Parkinson Disease; Piperazines; Quinolines; Rats; Rats, Sprague-Dawley; Time Factors | 2004 |
The antioxidant drink effective microorganism-X (EM-X) pre-treatment attenuates the loss of nigrostriatal dopaminergic neurons in 6-hydroxydopamine-lesion rat model of Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antioxidants; Beverages; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Glycosides; Kaempferols; Male; Neurons; Neuroprotective Agents; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Substantia Nigra; Time Factors; Tyrosine 3-Monooxygenase | 2004 |
Rasagiline enhances L-DOPA-induced contralateral turning in the unilateral 6-hydroxydopamine-lesioned guinea-pig.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Dopamine; Functional Laterality; Guinea Pigs; Homovanillic Acid; Indans; Male; Models, Neurological; Monoamine Oxidase Inhibitors; Motor Activity; Neuroprotective Agents; Oxidopamine; Reproducibility of Results; Substantia Nigra | 2004 |
Novel dopamine releasing response of an anti-convulsant agent with possible anti-Parkinson's activity.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Animals; Antiparkinson Agents; Behavior, Animal; Carbidopa; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Agents; Homovanillic Acid; Isoxazoles; Levodopa; Microdialysis; Oxidopamine; Parkinson Disease; Rats; Zonisamide | 2004 |
SL25.1131 [3(S),3a(S)-3-methoxymethyl-7-[4,4,4-trifluorobutoxy]-3,3a,4,5-tetrahydro-1,3-oxazolo[3,4-a]quinolin-1-one], a new, reversible, and mixed inhibitor of monoamine oxidase-A and monoamine oxidase-B: biochemical and behavioral profile.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benzophenones; Brain; Corpus Striatum; Disease Models, Animal; Dopamine; Drug Interactions; Levodopa; Maze Learning; Mice; Mice, Inbred C57BL; Monoamine Oxidase; Monoamine Oxidase Inhibitors; MPTP Poisoning; Nervous System Diseases; Nitrophenols; Oxazoles; Oxidopamine; Prefrontal Cortex; Quinolines; Rats; Rats, Sprague-Dawley; Serotonin; Stereotyped Behavior; Tolcapone; Tremor; Tyramine | 2004 |
Olfactory ensheathing cell transplantation restores functional deficits in rat model of Parkinson's disease: a cotransplantation approach with fetal ventral mesencephalic cells.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Brain Tissue Transplantation; Cell Transplantation; Cells, Cultured; Dextroamphetamine; Dopamine; Dopamine Agents; Female; Fetal Tissue Transplantation; Immunohistochemistry; Male; Mesencephalon; Olfactory Pathways; Oxidopamine; Parkinson Disease; Rats; Rats, Wistar; Receptors, Dopamine D2; Sympatholytics | 2004 |
Sparing of behavior and basal extracellular dopamine after 6-hydroxydopamine lesions of the nigrostriatal pathway in rats exposed to a prelesion sensitizing regimen of amphetamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Amphetamine; Analysis of Variance; Animals; Behavior, Animal; Brain Diseases; Cell Count; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Extracellular Space; Homovanillic Acid; Immunohistochemistry; Male; Microdialysis; Oxidopamine; Physical Conditioning, Animal; Psychomotor Performance; Rats; Rats, Long-Evans; Stereotyped Behavior; Substantia Nigra; Time Factors; Tyrosine 3-Monooxygenase | 2004 |
Co-transplantation of carotid body and ventral mesencephalic cells as an alternative approach towards functional restoration in 6-hydroxydopamine-lesioned rats: implications for Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Binding, Competitive; Brain Tissue Transplantation; Carotid Body; Caudate Nucleus; Cells, Cultured; Dextroamphetamine; Disease Models, Animal; Dopamine; Female; Graft Survival; Mesencephalon; Motor Activity; Oxidopamine; Parkinsonian Disorders; Putamen; Rats; Rats, Wistar; Receptors, Dopamine D2; Recovery of Function; Tyrosine 3-Monooxygenase | 2004 |
Neuroprotective and neurotrophic effect of apomorphine in the striatal 6-OHDA-lesion rat model of Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Behavior, Animal; Chromatography, High Pressure Liquid; Corpus Striatum; Dialysis; Disease Models, Animal; Dopamine; Drug Interactions; Electrochemistry; Hydroxybenzoates; Immunohistochemistry; Male; Neuroprotective Agents; Oxidopamine; Parkinson Disease; Psychomotor Performance; Rats; Rats, Wistar; Stereotyped Behavior; Time Factors; Tyrosine 3-Monooxygenase; Ventral Tegmental Area | 2004 |
AMPA receptor blockade potentiates the stimulatory effect of L-DOPA on dopamine release in dopamine-deficient corticostriatal slice preparation.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benzodiazepines; Cerebral Cortex; Dopamine; Dopamine Agents; Electric Stimulation; Homovanillic Acid; In Vitro Techniques; Levodopa; Neostriatum; Oxidopamine; Rats; Receptors, AMPA; Sympatholytics | 2004 |
Dopamine agonist cabergoline inhibits levodopa-induced caspase activation in 6-OHDA-lesioned mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Cabergoline; Carbidopa; Caspases; Disease Models, Animal; Dopamine; Dopamine Agents; Dopamine Agonists; Drug Combinations; Drug Interactions; Enzyme Activation; Ergolines; Glutathione; Homovanillic Acid; Levodopa; Male; Mice; Mice, Inbred ICR; Neurotoxicity Syndromes; Oxidopamine; Thiobarbituric Acid Reactive Substances | 2005 |
Histological, behavioural and neurochemical evaluation of medial forebrain bundle and striatal 6-OHDA lesions as rat models of Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Behavior, Animal; Brain Chemistry; Cell Count; Corpus Striatum; Diagnostic Imaging; Disease Models, Animal; Dopamine; Evaluation Studies as Topic; Immunohistochemistry; Male; Maze Learning; Medial Forebrain Bundle; Motor Activity; Oxidopamine; Parkinson Disease; Psychomotor Performance; Rats; Rats, Wistar; Stereotyped Behavior; Time Factors; Tyrosine 3-Monooxygenase | 2005 |
Effect of AdGDNF on dopaminergic neurotransmission in the striatum of 6-OHDA-treated rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Amphetamine; Analysis of Variance; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Drug Interactions; Glial Cell Line-Derived Neurotrophic Factor; Homovanillic Acid; Male; Microdialysis; Nerve Growth Factors; Oxidopamine; Potassium Chloride; Rats; Rats, Inbred F344; Time Factors; Tyrosine 3-Monooxygenase | 2005 |
Pramipexole has ameliorating effects on levodopa-induced abnormal dopamine turnover in parkinsonian striatum and quenching effects on dopamine-semiquinone generated in vitro.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Antiparkinson Agents; Benzoquinones; Benzothiazoles; Corpus Striatum; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Electron Spin Resonance Spectroscopy; Functional Laterality; Homovanillic Acid; Levodopa; Male; Mice; Mice, Inbred ICR; Oxidopamine; Parkinson Disease; Pramipexole; Thiazoles; Time Factors | 2005 |
Neuroprotection by crocetin in a hemi-parkinsonian rat model.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Behavior, Animal; Carotenoids; Catalase; Corpus Striatum; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Homovanillic Acid; Male; Motor Activity; Neuroprotective Agents; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Wistar; Substantia Nigra; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Vitamin A | 2005 |
UCM707, an inhibitor of the anandamide uptake, behaves as a symptom control agent in models of Huntington's disease and multiple sclerosis, but fails to delay/arrest the progression of different motor-related disorders.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Arachidonic Acids; Brain Chemistry; Disease Models, Animal; Disease Progression; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Electrochemistry; Encephalomyelitis, Autoimmune, Experimental; Endocannabinoids; Exploratory Behavior; Furans; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Huntington Disease; Male; Malonates; Movement Disorders; Multiple Sclerosis; Nitro Compounds; Oxidopamine; Polyunsaturated Alkamides; Propionates; Rats; Rats, Sprague-Dawley; Time Factors; Tyrosine 3-Monooxygenase | 2006 |
Zingerone [4-(4-hydroxy-3-methoxyphenyl)-2-butanone] prevents 6-hydroxydopamine-induced dopamine depression in mouse striatum and increases superoxide scavenging activity in serum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Catalase; Dopamine; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Glutathione Peroxidase; Guaiacol; Homovanillic Acid; Hydroxyl Radical; Male; Mice; Mice, Inbred ICR; Neostriatum; Nerve Tissue Proteins; Oxidopamine; Superoxides; Sympatholytics | 2005 |
Dopamine D1 and D2 receptor contributions to L-DOPA-induced dyskinesia in the dopamine-depleted rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Behavior, Animal; Benzazepines; Corpus Striatum; Dopamine; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Drug Synergism; Dyskinesia, Drug-Induced; Hydroxyindoleacetic Acid; Levodopa; Male; Norepinephrine; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Salicylamides; Serotonin | 2005 |
Effects of anaesthetics on the loss of nigrostriatal dopaminergic neurons by 6-hydroxydopamine in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Analysis of Variance; Anesthetics; Animals; Cell Count; Cell Death; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Homovanillic Acid; Immunohistochemistry; Male; Neurons; Oxidopamine; Rats; Rats, Sprague-Dawley; Substantia Nigra; Tyrosine 3-Monooxygenase | 2006 |
Neonatal depletion of cortical dopamine: effects on dopamine turnover and motor behavior in juvenile and adult rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Aging; Analysis of Variance; Animals; Animals, Newborn; Behavior, Animal; Brain Chemistry; Chromatography, High Pressure Liquid; Denervation; Dopamine; Electrochemistry; Motor Activity; Norepinephrine; Oxidopamine; Prefrontal Cortex; Random Allocation; Rats; Rats, Sprague-Dawley; Time Factors | 2005 |
Effects of iptakalim on extracellular glutamate and dopamine levels in the striatum of unilateral 6-hydroxydopamine-lesioned rats: a microdialysis study.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Extracellular Space; Glutamic Acid; Male; Microdialysis; Oxidopamine; Propylamines; Rats; Rats, Sprague-Dawley; Substantia Nigra | 2006 |
Neuroprotective properties of the natural phenolic antioxidants curcumin and naringenin but not quercetin and fisetin in a 6-OHDA model of Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antioxidants; Curcumin; Disease Models, Animal; Dopamine; Flavanones; Flavonoids; Flavonols; Homovanillic Acid; Male; Neurons; Neuroprotective Agents; Oxidopamine; Parkinson Disease; Phenols; Quercetin; Rats; Rats, Sprague-Dawley; Tyrosine 3-Monooxygenase | 2005 |
Desipramine attenuates working memory impairments induced by partial loss of catecholamines in the rat medial prefrontal cortex.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antidepressive Agents; Catecholamines; Desipramine; Dopamine; Infusion Pumps, Implantable; Male; Maze Learning; Memory Disorders; Memory, Short-Term; Norepinephrine; Oxidopamine; Prefrontal Cortex; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Sympathectomy, Chemical; Sympatholytics | 2006 |
Nerve growth factor increases survival of dopaminergic graft, rescue nigral dopaminergic neurons and restores functional deficits in rat model of Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cell Transplantation; Corpus Striatum; Dopamine; Embryo, Mammalian; Female; Immunohistochemistry; Mesencephalon; Motor Activity; Nerve Growth Factor; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Wistar; Stereotyped Behavior; Substantia Nigra; Tyrosine 3-Monooxygenase | 2006 |
Postnatal administration of D1 dopamine agonist reverses neonatal dopaminergic lesion-induced changes in striatal enkephalin and substance P systems.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Animals; Animals, Newborn; Corpus Striatum; Dopamine; Drug Interactions; Enkephalins; Female; Gene Expression; Humans; Male; Oxidopamine; Pregnancy; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Substance P | 2006 |
Further validation of the corridor task for assessing deficit and recovery in the hemi-Parkinsonian rat: restoration of bilateral food retrieval by dopamine receptor agonism.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Behavior, Animal; Brain Chemistry; Chromatography, High Pressure Liquid; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Agonists; Feeding Behavior; Functional Laterality; Homovanillic Acid; Oxidopamine; Parkinson Disease; Rats; Recovery of Function; Reproducibility of Results | 2006 |
Increased slow oscillatory activity in substantia nigra pars reticulata triggers abnormal involuntary movements in the 6-OHDA-lesioned rat in the presence of excessive extracellular striatal dopamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Animals; Behavior, Animal; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Dopamine Agents; Dyskinesias; Extracellular Fluid; Homovanillic Acid; Levodopa; Male; Membrane Potentials; Microdialysis; Neurons; Oxidopamine; Rats; Rats, Wistar; Substantia Nigra | 2006 |
Forebrain D1 function and sensorimotor gating in rats: effects of D1 blockade, frontal lesions and dopamine denervation.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acoustic Stimulation; Animals; Behavior, Animal; Benzazepines; Chromatography, High Pressure Liquid; Denervation; Dopamine; Dopamine Antagonists; Lameness, Animal; Male; Norepinephrine; Oxidopamine; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Reflex, Startle; Serotonin; Sympatholytics; Time Factors | 2006 |
Neuroanatomical localization of an internal clock: a functional link between mesolimbic, nigrostriatal, and mesocortical dopaminergic systems.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Brain Chemistry; Chromatography, High Pressure Liquid; Conditioning, Operant; Corpus Striatum; Dopamine; Electrochemistry; Limbic System; Male; Oxidopamine; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Time Perception | 2006 |
CGP 56999A, a GABA(B) receptor antagonist, enhances expression of brain-derived neurotrophic factor and attenuates dopamine depletion in the rat corpus striatum following a 6-hydroxydopamine lesion of the nigrostriatal pathway.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain-Derived Neurotrophic Factor; Corpus Striatum; Denervation; Disease Models, Animal; Dopamine; GABA Antagonists; GABA-B Receptor Antagonists; Gene Expression; Male; Neural Inhibition; Neural Pathways; Oxidopamine; Parkinsonian Disorders; Phosphinic Acids; Rats; Rats, Inbred F344; Receptors, GABA-B; Substantia Nigra; Sympatholytics; Synaptic Transmission; Treatment Outcome; Up-Regulation | 2006 |
Protease-activated receptor-1 mediates protection elicited by thrombin preconditioning in a rat 6-hydroxydopamine model of Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Biotransformation; Catecholamines; Forelimb; Homovanillic Acid; Male; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Receptor, PAR-1; Receptors, Thrombin; Sympatholytics; Thrombin; Vibrissae | 2006 |
Selective activation of group III metabotropic glutamate receptors by L-(+)-2-amino-4-phosphonobutryic acid protects the nigrostriatal system against 6-hydroxydopamine toxicity in vivo.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aminobutyrates; Animals; Corpus Striatum; gamma-Aminobutyric Acid; Homovanillic Acid; Male; Neuroprotective Agents; Oxidopamine; Phosphoserine; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Substantia Nigra | 2007 |
Effect of subthalamic nucleus lesions in a 6-hydroxydopamine-induced rat parkinsonian model: behavioral and biochemical studies.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dominance, Cerebral; Dopamine; Globus Pallidus; Kainic Acid; Male; Motor Activity; Motor Skills; Neural Pathways; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Stereotyped Behavior; Subthalamic Nucleus | 2006 |
Effects of 2,3-benzodiazepine AMPA receptor antagonists on dopamine turnover in the striatum of rats with experimental parkinsonism.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Benzodiazepines; Corpus Striatum; Dopamine; Dopamine Agents; Drug Interactions; Functional Laterality; Homovanillic Acid; Levodopa; Male; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Receptors, AMPA | 2007 |
Amphetamine and mCPP effects on dopamine and serotonin striatal in vivo microdialysates in an animal model of hyperactivity.
Topics: 3,4-Dihydroxyphenylacetic Acid; 5,6-Dihydroxytryptamine; Age Factors; Amphetamine; Animals; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Corpus Striatum; Disease Models, Animal; Dopamine; Female; Hydroxyindoleacetic Acid; Male; Microdialysis; Oxidopamine; Piperazines; Pregnancy; Rats; Rats, Wistar; Serotonin; Serotonin Receptor Agonists; Sympatholytics | 2007 |
The regulation of liver cytochrome p450 by the brain dopaminergic system.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Blotting, Western; Brain; Brain Chemistry; Cytochrome P-450 Enzyme System; Dopamine; Gene Expression Regulation, Enzymologic; Homovanillic Acid; In Vitro Techniques; Isoenzymes; Limbic System; Liver; Male; Neostriatum; Oxidopamine; Rats; Rats, Wistar; Signal Transduction; Sympatholytics | 2007 |
High-frequency stimulation of the subthalamic nucleus prolongs the increase in striatal dopamine induced by acute l-3,4-dihydroxyphenylalanine in dopaminergic denervated rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Data Interpretation, Statistical; Denervation; Dihydroxyphenylalanine; Dopamine; Dopamine Agents; Electric Stimulation; Extracellular Space; Homovanillic Acid; Male; Microdialysis; Neostriatum; Oxidopamine; Rats; Rats, Sprague-Dawley; Subthalamic Nucleus; Synaptic Transmission | 2007 |
Modulation of the motor response to dopaminergic drugs in a parkinsonian model of combined dopaminergic and noradrenergic degeneration.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adenosine A2 Receptor Antagonists; Adrenergic Agents; Animals; Antiparkinson Agents; Behavior, Animal; Benzylamines; Brain; Caffeine; Dopamine; Dopamine Agents; Homovanillic Acid; Levodopa; Male; Motor Activity; Neurotoxins; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley | 2007 |
Pael receptor is involved in dopamine metabolism in the nigrostriatal system.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Drug Resistance; Genetic Predisposition to Disease; Humans; Male; Mice; Mice, Knockout; Mice, Transgenic; Neural Pathways; Neurotoxins; Oxidopamine; Parkinsonian Disorders; Receptors, G-Protein-Coupled; Substantia Nigra; Ubiquitin-Protein Ligases | 2007 |
Intrastriatal inhibition of aromatic amino acid decarboxylase prevents l-DOPA-induced dyskinesia: a bilateral reverse in vivo microdialysis study in 6-hydroxydopamine lesioned rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Aromatic-L-Amino-Acid Decarboxylases; Behavior, Animal; Benserazide; Brain Injuries; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Agents; Drug Interactions; Dyskinesia, Drug-Induced; Enzyme Inhibitors; Homovanillic Acid; Levodopa; Male; Microdialysis; Oxidopamine; Rats; Rats, Wistar | 2008 |
Echinacoside prevents the striatal extracellular levels of monoamine neurotransmitters from diminution in 6-hydroxydopamine lesion rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Glycosides; Homovanillic Acid; Male; Oxidopamine; Rats; Rats, Wistar | 2007 |
6-Hydroxydopamine lesion in the ventral tegmental area fails to reduce extracellular dopamine in the cerebral cortex.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Cerebral Cortex; Dopamine; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Drug Interactions; Extracellular Fluid; Haloperidol; Isoquinolines; Male; Microdialysis; Naphthyridines; Norepinephrine; Oxidopamine; Rats; Rats, Sprague-Dawley; Sympatholytics; Ventral Tegmental Area | 2008 |
Zuckerkandl's organ improves long-term survival and function of neural stem cell derived dopaminergic neurons in Parkinsonian rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Bromodeoxyuridine; Cell Differentiation; Coculture Techniques; Disease Models, Animal; Dopamine; Female; Functional Laterality; Gene Expression Regulation; Intercellular Signaling Peptides and Proteins; Motor Activity; Nerve Tissue Proteins; Neurons; Organ Culture Techniques; Oxidopamine; Paraganglia, Chromaffin; Parkinsonian Disorders; Protein Binding; Rats; Rats, Wistar; Receptors, Dopamine D2; Stem Cell Transplantation | 2008 |
Generation of a alpha-synuclein-based rat model of Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; alpha-Synuclein; Analysis of Variance; Animals; Apomorphine; Behavior, Animal; Disease Models, Animal; Dopamine Agonists; Gene Expression Regulation; Gene Products, tat; Genetic Vectors; Green Fluorescent Proteins; Male; Motor Activity; Oxidopamine; Parkinson Disease; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Substantia Nigra; Time Factors; Tyrosine 3-Monooxygenase | 2008 |
The vermicelli handling test: a simple quantitative measure of dexterous forepaw function in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Dopamine; Food; Forelimb; Homovanillic Acid; Infarction, Middle Cerebral Artery; Male; Motor Cortex; Motor Skills; Neostriatum; Observer Variation; Oxidopamine; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Somatosensory Cortex; Stereotaxic Techniques; Sympatholytics | 2008 |
In vivo neurochemical effects of the NR2B selective NMDA receptor antagonist CR 3394 in 6-hydroxydopamine lesioned rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adamantane; Amidines; Animals; Antiparkinson Agents; Basal Ganglia; Denervation; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Injections, Intraperitoneal; Levodopa; Male; Medial Forebrain Bundle; Microdialysis; Oxidopamine; Parkinsonian Disorders; Perfusion; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Time Factors | 2008 |
Docosahexaenoic acid ethyl ester enhances 6-hydroxydopamine-induced neuronal damage by induction of lipid peroxidation in mouse striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Docosahexaenoic Acids; Dopamine; Homovanillic Acid; Lipid Peroxidation; Male; Mice; Mice, Inbred ICR; Neostriatum; Oxidative Stress; Oxidopamine; Thiobarbituric Acid Reactive Substances | 2009 |
Ketogenic diet protects dopaminergic neurons against 6-OHDA neurotoxicity via up-regulating glutathione in a rat model of Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Animals; Brain; Brain Chemistry; Chromatography, High Pressure Liquid; Diet, Ketogenic; Dopamine; Glutathione; Homovanillic Acid; Immunohistochemistry; Nerve Degeneration; Neurons; Oxidopamine; Parkinsonian Disorders; Rats; Tyrosine 3-Monooxygenase; Up-Regulation | 2009 |
Acute L: -DOPA effect on hydroxyl radical- and DOPAC-levels in striatal microdialysates of parkinsonian rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antiparkinson Agents; Corpus Striatum; Disease Models, Animal; Female; Hydroxyindoleacetic Acid; Hydroxyl Radical; Injections, Intraventricular; Levodopa; Male; Microdialysis; Oxidopamine; Parkinsonian Disorders; Pregnancy; Rats; Sympatholytics; Time Factors | 2010 |
Vasoactive intestinal peptide (VIP) treatment of Parkinsonian rats increases thalamic gamma-aminobutyric acid (GABA) levels and alters the release of nerve growth factor (NGF) by mast cells.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Female; gamma-Aminobutyric Acid; Heparin; Male; Mast Cells; Microdialysis; Nerve Growth Factor; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Serotonin; Thalamus; Vasoactive Intestinal Peptide | 2010 |
Functional enhancement and protection of dopaminergic terminals by RAB3B overexpression.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cell Line; Corpus Striatum; Dopamine; Female; Gene Expression; Gene Expression Profiling; Humans; In Vitro Techniques; Leupeptins; Levodopa; Models, Neurological; Oxidopamine; Parkinson Disease; Parkinsonian Disorders; Presynaptic Terminals; rab3 GTP-Binding Proteins; Rats; Rats, Sprague-Dawley; RNA, Messenger; Substantia Nigra; Synaptic Vesicles; Ventral Tegmental Area | 2009 |
Pre-synaptic glutamate-induced activation of DA release in the striatum after partial nigral lesion.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amino Acids; Animals; Brain Injuries; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Dopamine Agents; Electrochemotherapy; Glutamic Acid; Homovanillic Acid; Male; Microdialysis; Oxidopamine; Presynaptic Terminals; Rats; Rats, Wistar; Substantia Nigra | 2010 |
On the role of P2X(7) receptors in dopamine nerve cell degeneration in a rat model of Parkinson's disease: studies with the P2X(7) receptor antagonist A-438079.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Analysis of Variance; Animals; Brain; Cell Count; Chromatography, High Pressure Liquid; Disease Models, Animal; Dopamine; Glial Fibrillary Acidic Protein; Homovanillic Acid; Male; Nerve Degeneration; Neural Pathways; Oxidopamine; Parkinson Disease; Purinergic P2 Receptor Antagonists; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Statistics, Nonparametric; Tetrazoles | 2010 |
Intake of tomato-enriched diet protects from 6-hydroxydopamine-induced degeneration of rat nigral dopaminergic neurons.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Carotenoids; Disease Models, Animal; Dopamine; Functional Laterality; Intramolecular Lyases; Male; Nerve Degeneration; Oxidopamine; Parkinson Disease; Plants, Genetically Modified; Rats; Rats, Inbred F344; Solanum lycopersicum; Substantia Nigra | 2009 |
Salicylic acid protects against chronic L-DOPA-induced 6-OHDA generation in experimental model of parkinsonism.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Agents; Homovanillic Acid; Levodopa; Male; Medial Forebrain Bundle; Mice; Mice, Inbred BALB C; Neuroprotective Agents; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Salicylates | 2010 |
Effects of 6-hydroxydopamine lesioning of the medial prefrontal cortex on social interactions in adolescent and adult rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Dopamine; Exploratory Behavior; Interpersonal Relations; Male; Motor Activity; Neurotoxicity Syndromes; Norepinephrine; Nucleus Accumbens; Oxidopamine; Prefrontal Cortex; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Sympatholytics | 2010 |
Within-session analysis of amphetamine-elicited rotation behavior reveals differences between young adult and middle-aged F344/BN rats with partial unilateral striatal dopamine depletion.
Topics: 3,4-Dihydroxyphenylacetic Acid; Age Factors; Amphetamines; Animals; Behavior, Animal; Corpus Striatum; Dopamine; Oxidopamine; Rats; Rats, Inbred F344 | 2010 |
Neurturin protects against 6-hydroxydopamine-induced reductions in evoked dopamine overflow in rat striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Dopamine Uptake Inhibitors; Functional Laterality; Glial Cell Line-Derived Neurotrophic Factor; Homovanillic Acid; Male; Microdialysis; Nerve Growth Factors; Neuroprotective Agents; Neurturin; Oxidopamine; Potassium Chloride; Rats; Rats, Inbred F344; Substantia Nigra; Sympatholytics | 2010 |
Age-specific effects of 6-hydroxydopamine lesions of the rat medial prefrontal cortex on stress-induced c-fos expression in subcortical areas.
Topics: 3,4-Dihydroxyphenylacetic Acid; Age Factors; Amygdala; Analysis of Variance; Animals; Chromatography, High Pressure Liquid; Dopamine; Hippocampus; Immunohistochemistry; Male; Neurons; Norepinephrine; Nucleus Accumbens; Oxidopamine; Prefrontal Cortex; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Restraint, Physical; Stress, Physiological | 2010 |
Functional reorganization of the presynaptic dopaminergic terminal in parkinsonism.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Analysis of Variance; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Disease Models, Animal; Dopamine; Electric Stimulation; Electrochemistry; Functional Laterality; Hydrazines; Male; Oxidopamine; Parkinsonian Disorders; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Time Factors; Tropanes | 2011 |
Effect of adenosine A(2A) receptor antagonists and L-DOPA on hydroxyl radical, glutamate and dopamine in the striatum of 6-OHDA-treated rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adenosine A2 Receptor Antagonists; Animals; Benserazide; Caffeine; Dopamine; Glutamic Acid; Hydroxyl Radical; Levodopa; Male; Microdialysis; Neostriatum; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Wistar; Receptor, Adenosine A2A; Triazines; Triazoles | 2012 |
Chronic progesterone treatment of male rats with unilateral 6-hydroxydopamine lesion of the dorsal striatum exacerbates [corrected] parkinsonian symptoms.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Motor Activity; Oxidopamine; Parkinsonian Disorders; Progesterone; Rats; Rats, Wistar | 2011 |
The metabotropic glutamate receptor 4-positive allosteric modulator VU0364770 produces efficacy alone and in combination with L-DOPA or an adenosine 2A antagonist in preclinical rodent models of Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adenosine A2 Receptor Antagonists; Animals; Brain; Calcium Signaling; Catalepsy; Corpus Striatum; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Glutamic Acid; Haloperidol; HEK293 Cells; Humans; Levodopa; Male; Monoamine Oxidase; Motor Neuron Disease; Oxidopamine; Parkinson Disease; Picolinic Acids; Protein Binding; Psychomotor Performance; Pyrimidines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reaction Time; Receptors, G-Protein-Coupled; Receptors, Metabotropic Glutamate; Substantia Nigra; Thallium; Transfection; Triazoles; Tyrosine 3-Monooxygenase | 2012 |
Neuroprotective effect of sesame seed oil in 6-hydroxydopamine induced neurotoxicity in mice model: cellular, biochemical and neurochemical evidence.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Enzymes; Male; Mice; Neuroprotective Agents; Oxidative Stress; Oxidopamine; Sesame Oil | 2012 |
Intranasally applied L-DOPA alleviates parkinsonian symptoms in rats with unilateral nigro-striatal 6-OHDA lesions.
Topics: 3,4-Dihydroxyphenylacetic Acid; Administration, Intranasal; Amphetamine; Analysis of Variance; Animals; Antiparkinson Agents; Benserazide; Chromatography, High Pressure Liquid; Corpus Striatum; Disease Models, Animal; Dopamine; Electrochemistry; Exploratory Behavior; Forelimb; Functional Laterality; Homovanillic Acid; Hydroxyindoleacetic Acid; Levodopa; Male; Motor Activity; Motor Skills; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Wistar; Substantia Nigra; Sympatholytics | 2012 |
Contralateral retinal dopamine decrease and melatonin increase in progression of hemiparkinsonium rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Chromatography, High Pressure Liquid; Disease Progression; Dopamine; Homovanillic Acid; Melatonin; Oxidopamine; Parkinson Disease; Rats; Retina; Spectrometry, Fluorescence | 2012 |
Prostaglandin E2-mediated attenuation of mesocortical dopaminergic pathway is critical for susceptibility to repeated social defeat stress in mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Benzazepines; Calcium-Binding Proteins; Corticosterone; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; Disease Susceptibility; Dominance-Subordination; Dopamine; Dopamine Antagonists; Homovanillic Acid; Interpersonal Relations; Maze Learning; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Knockout; Microfilament Proteins; Neural Pathways; Oxidopamine; Prefrontal Cortex; Pyrazoles; Receptors, Prostaglandin E; Signal Transduction; Stress, Psychological; Sulfonamides; Time Factors; Tyrosine 3-Monooxygenase; Ventral Tegmental Area | 2012 |
Nonuniform cardiac denervation observed by 11C-meta-hydroxyephedrine PET in 6-OHDA-treated monkeys.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Blood Pressure; Carbon Radioisotopes; Dopamine; Echocardiography; Ephedrine; Female; Heart; Macaca mulatta; Male; Neurons; Norepinephrine; Oxidopamine; Positron-Emission Tomography; Primary Dysautonomias; Radiopharmaceuticals | 2012 |
6-OHDA injections into A8-A9 dopaminergic neurons modelling early stages of Parkinson's disease increase the harmaline-induced tremor in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Animals; Central Nervous System Stimulants; Cerebellum; Chromatography, High Pressure Liquid; Dopaminergic Neurons; Harmaline; Hydroxyindoleacetic Acid; Male; Motor Activity; Oxidopamine; Parkinson Disease; Rats; Rats, Wistar; Serotonin; Statistics, Nonparametric; Substantia Nigra; Tremor; Tyrosine 3-Monooxygenase | 2012 |
Increased melatonin may play dual roles in the striata of a 6-hydroxydopamine model of Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Data Interpretation, Statistical; Disease Models, Animal; Dopamine; Homovanillic Acid; Male; Melatonin; Microdialysis; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley | 2013 |
GABAA-receptor activation in the subthalamic nucleus compensates behavioral asymmetries in the hemiparkinsonian rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Amphetamine; Animals; Disease Models, Animal; Dizocilpine Maleate; Dopamine; Dose-Response Relationship, Drug; Functional Laterality; GABA-A Receptor Agonists; Homovanillic Acid; Male; Medial Forebrain Bundle; Mental Disorders; Muscimol; Neuroprotective Agents; Oxidopamine; Parkinson Disease; Rats; Rats, Wistar; Receptors, GABA-A; Statistics, Nonparametric; Subthalamic Nucleus; Time Factors | 2013 |
Neuroprotective effect of hydroxysafflor yellow A on 6-hydroxydopamine-induced Parkinson's disease in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Behavior, Animal; Chalcone; Gene Expression Regulation, Enzymologic; Homovanillic Acid; Male; Neostriatum; Neuroprotective Agents; Oxidopamine; Parkinson Disease; Quinones; Rats; Rats, Sprague-Dawley; Rotation; Substantia Nigra; Tyrosine 3-Monooxygenase | 2013 |
The subthalamic activity and striatal monoamine are modulated by subthalamic stimulation.
Topics: 3,4-Dihydroxyphenylacetic Acid; Action Potentials; Animals; Biogenic Monoamines; Chromatography, High Pressure Liquid; Corpus Striatum; Disease Models, Animal; Dopamine; Electric Stimulation; Female; Homovanillic Acid; Motor Activity; Neurons; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Spectrum Analysis; Subthalamic Nucleus | 2014 |
Chronic L-DOPA treatment attenuates behavioral and biochemical deficits induced by unilateral lactacystin administration into the rat substantia nigra.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcysteine; Adrenergic Agents; Animals; Antiparkinson Agents; Apomorphine; Catalepsy; Cysteine Proteinase Inhibitors; Dopamine Agonists; Dose-Response Relationship, Drug; Functional Laterality; Levodopa; Male; Oxidopamine; Rats; Rats, Wistar; Reaction Time; Serotonin; Substantia Nigra | 2014 |
Caffeine neuroprotective effects on 6-OHDA-lesioned rats are mediated by several factors, including pro-inflammatory cytokines and histone deacetylase inhibitions.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Animals; Apomorphine; Brain; Caffeine; Cytokines; Dopamine; Dopamine Agonists; Dose-Response Relationship, Drug; Exploratory Behavior; Histone Deacetylases; Male; Motor Activity; Neuroprotective Agents; Oxidopamine; Parkinson Disease; Rats; Rats, Wistar; Tyrosine 3-Monooxygenase | 2014 |
PEGylated rhFGF-2 conveys long-term neuroprotection and improves neuronal function in a rat model of Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Apoptosis; Astrocytes; Behavior, Animal; Biological Availability; Cell Survival; Disease Models, Animal; Dopaminergic Neurons; Fibroblast Growth Factor 2; Glial Fibrillary Acidic Protein; Male; Neostriatum; Neuroprotective Agents; Oxidopamine; Parkinson Disease; PC12 Cells; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Substantia Nigra; Tyrosine 3-Monooxygenase | 2015 |
A potential target for the treatment of Parkinson's disease: effect of lateral habenula lesions.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Animals; Apomorphine; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Agonists; Habenula; Homovanillic Acid; Male; Medial Forebrain Bundle; Neurosurgery; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Tyrosine 3-Monooxygenase | 2014 |
AAV.shRNA-mediated downregulation of ROCK2 attenuates degeneration of dopaminergic neurons in toxin-induced models of Parkinson's disease in vitro and in vivo.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Animals; Dependovirus; Disease Models, Animal; Dopaminergic Neurons; Down-Regulation; Genetic Vectors; Homovanillic Acid; Lim Kinases; Nerve Degeneration; Oxidopamine; Parkinson Disease; Psychomotor Performance; Rats; Rats, Wistar; rho-Associated Kinases; RNA, Small Interfering; Substantia Nigra; Tyrosine 3-Monooxygenase | 2015 |
Decreased behavioral response to intranigrally administered GABAA agonist muscimol in the lactacystin model of Parkinson's disease may result from partial lesion of nigral non-dopamine neurons: comparison to the classical neurotoxin 6-OHDA.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcysteine; Animals; Cell Count; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; GABA-A Receptor Agonists; Homovanillic Acid; Locomotion; Male; Muscimol; Neurons; Oxidopamine; Parkinson Disease; Parkinsonian Disorders; Rats, Wistar; Receptors, GABA-A; Substantia Nigra | 2015 |
Differential degradation of motor deficits during gradual dopamine depletion with 6-hydroxydopamine in mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Animals; Chromatography, High Pressure Liquid; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Exploratory Behavior; Female; Homovanillic Acid; Male; Medial Forebrain Bundle; Mice; Mice, Inbred C57BL; Movement Disorders; Norepinephrine; Oxidopamine; Psychomotor Performance; Serotonin; Time Factors | 2015 |
Protective role of chrysin on 6-hydroxydopamine-induced neurodegeneration a mouse model of Parkinson's disease: Involvement of neuroinflammation and neurotrophins.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biomarkers; Dopamine; Flavonoids; Gene Expression Regulation; Homovanillic Acid; Inflammation; Male; Mice; Mice, Inbred C57BL; Nerve Growth Factors; Oxidopamine; Parkinson Disease, Secondary; Random Allocation | 2018 |
Destruction of noradrenergic terminals increases dopamine concentration and reduces dopamine metabolism in the medial prefrontal cortex.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic alpha-2 Receptor Antagonists; Animals; Dihydroxyphenylalanine; Dopamine; Dopamine Uptake Inhibitors; Extracellular Space; Male; Neural Pathways; Neurons; Norepinephrine; Oxidopamine; Piperazines; Prefrontal Cortex; Rats, Wistar; Yohimbine | 2018 |
Therapeutic efficacy of regulable GDNF expression for Huntington's and Parkinson's disease by a high-induction, background-free "GeneSwitch" vector.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Animals; Disease Models, Animal; Gene Expression Regulation; Glial Cell Line-Derived Neurotrophic Factor; Green Fluorescent Proteins; Homovanillic Acid; Hormone Antagonists; Huntingtin Protein; Huntington Disease; Mice; Mice, Transgenic; Mifepristone; Oxidopamine; Parkinson Disease; Synapsins; Synucleins; Transduction, Genetic | 2018 |
Chrysin protects against behavioral, cognitive and neurochemical alterations in a 6-hydroxydopamine model of Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Cognition; Dopamine; Female; Flavonoids; Homovanillic Acid; Lipid Peroxidation; Maze Learning; Mice; Neuroprotective Agents; Nitric Oxide Synthase; Oxidative Stress; Oxidopamine; Parkinson Disease, Secondary; Reactive Oxygen Species | 2019 |
p-Chloroamphetamine-Enhanced Neostriatal Dopamine Exocytosis in Rats Neonatally Co-lesioned with 6-OHDA and 5,7-DHT: Relevance to Parkinson's Disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; 5,7-Dihydroxytryptamine; Animals; Animals, Newborn; Dopamine; Exocytosis; Female; Male; Microdialysis; Neostriatum; Oxidopamine; p-Chloroamphetamine; Parkinson Disease; Rats; Serotonin | 2020 |
Hesperidin protects against behavioral alterations and loss of dopaminergic neurons in 6-OHDA-lesioned mice: the role of mitochondrial dysfunction and apoptosis.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apoptosis; Behavior, Animal; Discrimination Learning; Dopamine; Dopaminergic Neurons; Hesperidin; Male; Maze Learning; Mice; Mitochondria; Motor Activity; NADH Dehydrogenase; Oxidopamine; Parkinson Disease, Secondary; Tyrosine 3-Monooxygenase | 2021 |
Vitamin D (VD3) Intensifies the Effects of Exercise and Prevents Alterations of Behavior, Brain Oxidative Stress, and Neuroinflammation, in Hemiparkinsonian Rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Cholecalciferol; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Exercise; Neuroinflammatory Diseases; Oxidative Stress; Oxidopamine; Rats; Rats, Wistar; Tyrosine 3-Monooxygenase; Vitamin D | 2023 |