3,4-dihydroxyphenylacetic acid has been researched along with n-methyl-3,4-methylenedioxyamphetamine in 47 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (10.64) | 18.7374 |
| 1990's | 18 (38.30) | 18.2507 |
| 2000's | 14 (29.79) | 29.6817 |
| 2010's | 9 (19.15) | 24.3611 |
| 2020's | 1 (2.13) | 2.80 |
| Authors | Studies |
|---|---|
| Nash, JF; Yamamoto, BK | 1 |
| Fadayel, GM; Schmidt, CJ; Sullivan, CK; Taylor, VL | 1 |
| Katz, JL; Martello, AL; Martello, MB; Ricaurte, GA | 1 |
| Culp, S; DeSouza, EB; Lehmann, J; Zaczek, R | 1 |
| Cho, AK; Hiramatsu, M | 1 |
| Ali, SF; Gough, B; Holson, RR; Slikker, W | 1 |
| Chang, AS; Cho, AK; DiStefano, E; Hiramatsu, M | 1 |
| Huang, XM; Johnson, MP; Nichols, DE | 1 |
| Nash, JF | 1 |
| Lovenberg, W; Schmidt, CJ; Wu, L | 1 |
| Champney, TH; Frye, GD; Matthews, RT | 1 |
| Gibb, JW; Hanson, GR; Stahl, DC; Stone, DM | 1 |
| Gibb, JW; Hanson, GR; Johnson, M; Stone, DM | 1 |
| Spanos, LJ; Yamamoto, BK | 1 |
| Colado, MI; Green, AR | 1 |
| Fadayel, GM; Schmidt, CJ; Sullivan, CK | 1 |
| Ali, S; Cadet, JL; Carlson, E; Epstein, C; Hirata, H; Ladenheim, B; Moran, TH; Rothman, RB | 1 |
| Marona-Lewicka, D; Nichols, DE; Rhee, GS; Sprague, JE | 1 |
| Finnegan, KT; Taraska, T | 1 |
| Laverty, R; Russell, B; Schmierer, D; Zheng, Y | 1 |
| Malberg, JE; Seiden, LS | 1 |
| Andrews, AM; Cadet, JL; Jayanthi, S; Ladenheim, B | 1 |
| Chen, JP; Gardner, E; Hen, R; Scearce-Levie, K | 1 |
| Aguirre, N; Hervías, I; Lasheras, B | 1 |
| Camarero, J; Colado, MI; Esteban, B; Green, AR; O'Shea, E | 1 |
| Camarero, J; Colado, MI; Esteban, B; Green, AR; O'Shea, E; Sanchez, V | 1 |
| Ali, SF; Meyer, JS | 1 |
| Ali, SF; Blough, B; Gough, B; Imam, SZ; Slikker, W | 1 |
| Cord, BJ; Hatzidimitriou, G; McCann, UD; Ricaurte, GA; Yuan, J | 1 |
| Baumann, MH; Rothman, RB; Wang, X; Xu, H | 1 |
| Colado, MI; Elliott, JM; Green, AR; O'shea, E; Saadat, KS; Sanchez, V | 1 |
| Colado, MI; Escobedo, I; Green, AR; Navarro, M; O'Shea, E; Orio, L; Sanchez, V | 1 |
| Biagioni, F; Busceti, CL; di Poggio, AB; Ferrucci, M; Fornai, F; Giusiani, M; Lazzeri, G; Lenzi, P; Natale, G; Paparelli, A; Ruggieri, S | 1 |
| Ben Hamida, S; Cassel, JC; Jeltsch, H; Jones, BC; Kelche, C; Koenig, J; Lazarus, C; Riegert, C | 1 |
| Choi, FY; Crawford, CA; Kohutek, JL; McDougall, SA; Vorhees, CV; Williams, MT; Yoshida, ST | 1 |
| Callaghan, PD; Daws, LC; Farrand, K; Hughes, P; Irvine, RJ; Salem, A | 1 |
| Cherng, CG; Ho, MC; Ke, JJ; Tsai, CW; Tsai, YP; Yu, L | 1 |
| Cadet, JL; Huestis, MA; Ladenheim, B; Scheidweiler, KB | 1 |
| von Ameln, N; von Ameln-Mayerhofer, A | 1 |
| Irvine, RJ; Jaehne, EJ; Majumder, I; Salem, A | 1 |
| Banks, ML; Fantegrossi, WE; Godfrey, JR; Howell, LL; Murnane, KS | 1 |
| Aguilar, MA; Armario, A; Do Couto, BR; Fuentes, S; Gagliano, H; Miñarro, J; Rodríguez-Arias, M | 1 |
| Goiny, M; Ichinose, F; Kehr, J; Nyberg, F; Sievertsson, T; Yoshitake, S; Yoshitake, T | 1 |
| Aguilar, MA; Miñarro, J; Rodríguez-Arias, M; Vidal-Infer, A | 1 |
| Aguilar, MA; Blanco-Gandía, MC; Daza-Losada, M; Miñarro, J; Rodríguez-Arias, M; Valverde, O | 1 |
| Aguirre, N; Barros-Miñones, L; Beitia, G; Goñi-Allo, B; Puerta, E; Suquia, V | 1 |
| Bagwell, MS; Chitre, NM; Murnane, KS | 1 |
47 other study(ies) available for 3,4-dihydroxyphenylacetic acid and n-methyl-3,4-methylenedioxyamphetamine
| Article | Year |
|---|---|
Methamphetamine neurotoxicity and striatal glutamate release: comparison to 3,4-methylenedioxymethamphetamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; 3,4-Methylenedioxyamphetamine; Analysis of Variance; Animals; Aspartic Acid; Corpus Striatum; Designer Drugs; Dialysis; Dopamine; Glutamates; Kinetics; Male; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Neurotoxins; Rats; Rats, Wistar; Reference Values; Taurine; Time Factors | 1992 |
5-HT2 receptors exert a state-dependent regulation of dopaminergic function: studies with MDL 100,907 and the amphetamine analogue, 3,4-methylenedioxymethamphetamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; 3,4-Methylenedioxyamphetamine; Animals; Brain Chemistry; Dialysis; Dopamine; Fluorobenzenes; Haloperidol; Homovanillic Acid; Male; N-Methyl-3,4-methylenedioxyamphetamine; Piperidines; Rats; Rats, Sprague-Dawley; Reserpine; Serotonin Antagonists | 1992 |
Lasting effects of (+-)-3,4-methylenedioxymethamphetamine (MDMA) on central serotonergic neurons in nonhuman primates: neurochemical observations.
Topics: 3,4-Dihydroxyphenylacetic Acid; 3,4-Methylenedioxyamphetamine; Animals; Brain; Cell Membrane; Chromatography, High Pressure Liquid; Dopamine; Female; Hydroxyindoleacetic Acid; Injections, Subcutaneous; Male; N-Methyl-3,4-methylenedioxyamphetamine; Neurons; Norepinephrine; Paroxetine; Piperidines; Saimiri; Serotonin; Serotonin Antagonists | 1992 |
Regional distribution to recovery of 5-HT levels after administration of "atrophins" MDMA and D,L-fenfluramine. Stereospecificity and comparison with 5,7-dihydroxytryptamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; 3,4-Methylenedioxyamphetamine; 5,7-Dihydroxytryptamine; Animals; Atrophy; Brain; Cerebral Ventricles; Designer Drugs; Dopamine; Fenfluramine; Homovanillic Acid; Hydroxyindoleacetic Acid; Injections, Intraventricular; Male; N-Methyl-3,4-methylenedioxyamphetamine; Norepinephrine; Organ Specificity; Paroxetine; Piperidines; Rats; Rats, Inbred Strains; Serotonin; Stereoisomerism | 1992 |
Enantiomeric differences in the effects of 3,4-methylenedioxymethamphetamine on extracellular monoamines and metabolites in the striatum of freely-moving rats: an in vivo microdialysis study.
Topics: 3,4-Dihydroxyphenylacetic Acid; 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Biogenic Monoamines; Chromatography, High Pressure Liquid; Corpus Striatum; Dialysis; Dopamine; Electrochemistry; Fenclonine; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Serotonin; Stereoisomerism | 1990 |
Acute effects of 3,4-methylenedioxymethamphetamine (MDMA) on monoamines in rat caudate.
Topics: 3,4-Dihydroxyphenylacetic Acid; 3,4-Methylenedioxyamphetamine; Animals; Biogenic Monoamines; Caudate Nucleus; Chromatography, High Pressure Liquid; Dialysis; Dopamine; Electrochemistry; Female; Homovanillic Acid; Hydroxyindoleacetic Acid; In Vitro Techniques; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Serotonin | 1991 |
A pharmacokinetic analysis of 3,4-methylenedioxymethamphetamine effects on monoamine concentrations in brain dialysates.
Topics: 3,4-Dihydroxyphenylacetic Acid; 3,4-Methylenedioxyamphetamine; Animals; Biogenic Monoamines; Biological Availability; Brain Chemistry; Corpus Striatum; Dialysis; Dopamine; Gas Chromatography-Mass Spectrometry; Homovanillic Acid; Hydroxyindoleacetic Acid; Injections, Subcutaneous; Isomerism; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Serotonin | 1991 |
Serotonin neurotoxicity in rats after combined treatment with a dopaminergic agent followed by a nonneurotoxic 3,4-methylenedioxymethamphetamine (MDMA) analogue.
Topics: 3,4-Dihydroxyphenylacetic Acid; 3,4-Methylenedioxyamphetamine; Amphetamine; Animals; Brain; Dopamine; Dopamine Agents; Homovanillic Acid; Hydroxyindoleacetic Acid; Indans; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Serotonin | 1991 |
Ketanserin pretreatment attenuates MDMA-induced dopamine release in the striatum as measured by in vivo microdialysis.
Topics: 3,4-Dihydroxyphenylacetic Acid; 3,4-Methylenedioxyamphetamine; Animals; Corpus Striatum; Dialysis; Dopamine; Ketanserin; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Receptors, Serotonin | 1990 |
Methylenedioxymethamphetamine: a potentially neurotoxic amphetamine analogue.
Topics: 3,4-Dihydroxyphenylacetic Acid; 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Brain; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Serotonin; Time Factors | 1986 |
Effects of (+-)3,4-methylenedioxymethamphetamine (MDMA) on brain dopaminergic activity in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Behavior, Animal; Brain; Brain Chemistry; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Drug Tolerance; Haloperidol; Male; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Stereotyped Behavior; Time Factors | 1989 |
The effects of 3,4-methylenedioxymethamphetamine (MDMA) and 3,4-methylenedioxyamphetamine (MDA) on monoaminergic systems in the rat brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Biogenic Amines; Brain; Brain Chemistry; Dopamine; Homovanillic Acid; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Serotonin; Tyrosine 3-Monooxygenase | 1986 |
A comparison of the neurotoxic potential of methylenedioxyamphetamine (MDA) and its N-methylated and N-ethylated derivatives.
Topics: 3,4-Dihydroxyphenylacetic Acid; 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Brain; Corpus Striatum; Dopamine; Homovanillic Acid; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Tryptophan Hydroxylase; Tyrosine 3-Monooxygenase | 1987 |
The acute effects of methylenedioxymethamphetamine on dopamine release in the awake-behaving rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Brain; Caudate Nucleus; Consciousness; Dopamine; Male; N-Methyl-3,4-methylenedioxyamphetamine; Nucleus Accumbens; Rats; Rats, Inbred Strains | 1988 |
A study of the mechanism of MDMA ('ecstasy')-induced neurotoxicity of 5-HT neurones using chlormethiazole, dizocilpine and other protective compounds.
Topics: 3,4-Dihydroxyphenylacetic Acid; 3,4-Methylenedioxyamphetamine; 4-Butyrolactone; Animals; Brain; Chlormethiazole; Designer Drugs; Dizocilpine Maleate; Dopamine; Hydroxyindoleacetic Acid; Male; N-Methyl-3,4-methylenedioxyamphetamine; Ondansetron; Pentobarbital; Rats; Serotonin | 1994 |
Blockade of striatal 5-hydroxytryptamine2 receptors reduces the increase in extracellular concentrations of dopamine produced by the amphetamine analogue 3,4-methylenedioxymethamphetamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; 3,4-Methylenedioxyamphetamine; Animals; Corpus Striatum; Dialysis; Dopamine; Extracellular Space; Fluorobenzenes; Homovanillic Acid; Kinetics; N-Methyl-3,4-methylenedioxyamphetamine; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Antagonists; Tetrodotoxin | 1994 |
Superoxide radicals mediate the biochemical effects of methylenedioxymethamphetamine (MDMA): evidence from using CuZn-superoxide dismutase transgenic mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Autoradiography; Cocaine; Corpus Striatum; Dopamine; Female; Humans; Male; Mice; Mice, Transgenic; N-Methyl-3,4-methylenedioxyamphetamine; Receptors, Dopamine; Superoxide Dismutase; Superoxides; Tissue Distribution | 1995 |
Reinforcing effects of certain serotonin-releasing amphetamine derivatives.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamines; Animals; Conditioning, Operant; Dopamine; Dopamine Antagonists; Fenfluramine; Indans; Male; Microdialysis; N-Methyl-3,4-methylenedioxyamphetamine; Nucleus Accumbens; Rats; Reinforcement, Psychology; Serotonin; Serotonin Agents; Serotonin Receptor Agonists; Synaptic Transmission | 1996 |
Nitric oxide and the neurotoxic effects of methamphetamine and 3,4-methylenedioxymethamphetamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Body Temperature; Brain; Catecholamines; Corpus Striatum; Dopamine; Frontal Lobe; Hippocampus; Homovanillic Acid; Hydroxyindoleacetic Acid; Isosorbide Dinitrate; Male; Methamphetamine; Mice; Mice, Inbred Strains; N-Methyl-3,4-methylenedioxyamphetamine; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Rats; Rats, Sprague-Dawley; Serotonin | 1997 |
The effects of aminorex and related compounds on brain monoamines and metabolites in CBA mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aminorex; Animals; Appetite Depressants; Biogenic Monoamines; Brain Chemistry; Dopamine; Hydroxyindoleacetic Acid; Male; Mice; Mice, Inbred CBA; N-Methyl-3,4-methylenedioxyamphetamine; Serotonin | 1997 |
Small changes in ambient temperature cause large changes in 3,4-methylenedioxymethamphetamine (MDMA)-induced serotonin neurotoxicity and core body temperature in the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Body Temperature; Body Temperature Regulation; Brain Chemistry; Corpus Striatum; Dopamine; Fever; Frontal Lobe; Hippocampus; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; N-Methyl-3,4-methylenedioxyamphetamine; Neurotoxins; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Agents; Sodium Chloride; Somatosensory Cortex; Temperature | 1998 |
Overexpression of human copper/zinc superoxide dismutase in transgenic mice attenuates oxidative stress caused by methylenedioxymethamphetamine (Ecstasy).
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Catalase; Corpus Striatum; Dopamine; Glutathione Peroxidase; Homovanillic Acid; Hydroxyindoleacetic Acid; Lipid Peroxides; Mice; Mice, Transgenic; N-Methyl-3,4-methylenedioxyamphetamine; Oxidative Stress; Serotonin; Superoxide Dismutase | 1999 |
5-HT receptor knockout mice: pharmacological tools or models of psychiatric disorders.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aggression; Animals; Behavior, Animal; Cocaine; Disease Models, Animal; Dopamine; Dopamine Antagonists; Feeding Behavior; gamma-Aminobutyric Acid; Indoles; Mental Disorders; Mice; Mice, Knockout; N-Methyl-3,4-methylenedioxyamphetamine; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Substance-Related Disorders | 1999 |
2-Deoxy-D-glucose prevents and nicotinamide potentiates 3, 4-methylenedioxymethamphetamine-induced serotonin neurotoxicity.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adenosine Triphosphate; Animals; Body Temperature; Brain; Carrier Proteins; Corpus Striatum; Dopamine; Drug Synergism; Frontal Lobe; Hippocampus; Homovanillic Acid; Hydroxyindoleacetic Acid; Hypothermia; Male; Membrane Glycoproteins; Membrane Transport Proteins; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Tissue Proteins; Neurotoxins; Niacinamide; Organ Specificity; Paroxetine; Rats; Rats, Wistar; Serotonin; Serotonin Plasma Membrane Transport Proteins | 2000 |
Effect of GBR 12909 and fluoxetine on the acute and long term changes induced by MDMA ('ecstasy') on the 5-HT and dopamine concentrations in mouse brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Monoamines; Body Temperature; Brain Chemistry; Dopamine; Dopamine Uptake Inhibitors; Fluoxetine; Homovanillic Acid; Male; Mice; N-Methyl-3,4-methylenedioxyamphetamine; Piperazines; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Agents | 2001 |
3,4-Methylenedioxymethamphetamine induces monoamine release, but not toxicity, when administered centrally at a concentration occurring following a peripherally injected neurotoxic dose.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Monoamines; Dopamine; Hippocampus; Homovanillic Acid; Hydroxyindoleacetic Acid; Injections, Intraventricular; Male; Microdialysis; N-Methyl-3,4-methylenedioxyamphetamine; Perfusion; Rats; Serotonin; Serotonin Agents | 2001 |
Serotonergic neurotoxicity of MDMA (ecstasy) in the developing rat brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Apoptosis; Brain; Dopamine; Female; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; N-Methyl-3,4-methylenedioxyamphetamine; Neurotoxins; Organ Specificity; Rats; Rats, Sprague-Dawley; Serotonin | 2002 |
Comparative effects of substituted amphetamines (PMA, MDMA, and METH) on monoamines in rat caudate: a microdialysis study.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Amphetamines; Animals; Caudate Nucleus; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Methamphetamine; Microdialysis; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Sprague-Dawley; Serotonin | 2002 |
RETRACTED: Severe dopaminergic neurotoxicity in primates after a common recreational dose regimen of MDMA ("ecstasy").
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Autoradiography; Axons; Brain; Carrier Proteins; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Female; Hallucinogens; Humans; Hydroxyindoleacetic Acid; Male; Membrane Glycoproteins; Membrane Transport Proteins; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Degeneration; Nerve Tissue Proteins; Neurons; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Papio; Parkinsonian Disorders; Saimiri; Serotonin; Serotonin Plasma Membrane Transport Proteins; Symporters; Tremor; Tyrosine 3-Monooxygenase | 2002 |
3,4-methylenedioxymethamphetamine (MDMA) administration to rats decreases brain tissue serotonin but not serotonin transporter protein and glial fibrillary acidic protein.
Topics: 3,4-Dihydroxyphenylacetic Acid; 5,7-Dihydroxytryptamine; Animals; Astrocytes; Brain; Brain Chemistry; Carrier Proteins; Down-Regulation; Glial Fibrillary Acidic Protein; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Membrane Glycoproteins; Membrane Transport Proteins; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Tissue Proteins; Neurons; Neurotoxins; Norepinephrine; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Plasma Membrane Transport Proteins; Up-Regulation | 2004 |
Effect of repeated ('binge') dosing of MDMA to rats housed at normal and high temperature on neurotoxic damage to cerebral 5-HT and dopamine neurones.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Cerebral Cortex; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Heating; Hippocampus; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Endings; Neurons; Rats; Serotonin; Serotonin Agents; Time Factors | 2004 |
Elevation of ambient room temperature has differential effects on MDMA-induced 5-HT and dopamine release in striatum and nucleus accumbens of rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Body Temperature; Brain Chemistry; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Microdialysis; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Nucleus Accumbens; Rats; Serotonin; Serotonin Agents; Temperature; Time Factors | 2005 |
Occurrence of neuronal inclusions combined with increased nigral expression of alpha-synuclein within dopaminergic neurons following treatment with amphetamine derivatives in mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Uptake Inhibitors; Alkanes; alpha-Synuclein; Amides; Amphetamine; Analysis of Variance; Animals; Blotting, Western; Dopamine; Dopamine Uptake Inhibitors; Gene Expression Regulation; Glutamate Decarboxylase; Homovanillic Acid; Immunohistochemistry; Inclusion Bodies; Isoenzymes; Mice; Mice, Inbred C57BL; Microscopy, Electron, Transmission; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Tissue Proteins; Neurons; Substantia Nigra; Synucleins; Tyrosine 3-Monooxygenase | 2005 |
MDMA (ecstasy) effects in pubescent rats: Males are more sensitive than females.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Body Temperature; Brain; Chromatography, High Pressure Liquid; Dopamine; Dose-Response Relationship, Drug; Female; Hydroxyindoleacetic Acid; Male; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Norepinephrine; Random Allocation; Rats; Rats, Long-Evans; Serotonin; Sex Factors; Sexual Maturation; Survival Rate; Time Factors | 2005 |
Neonatal 3,4-methylenedioxymethamphetamine (MDMA) exposure alters neuronal protein kinase A activity, serotonin and dopamine content, and [35S]GTPgammaS binding in adult rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Age Factors; Animals; Animals, Newborn; Brain; Cyclic AMP-Dependent Protein Kinases; Dopamine; Female; Follow-Up Studies; Guanosine 5'-O-(3-Thiotriphosphate); Hallucinogens; Hippocampus; Male; N-Methyl-3,4-methylenedioxyamphetamine; Neurons; Prosencephalon; Random Allocation; Rats; Rats, Sprague-Dawley; Serotonin; Sex Factors | 2006 |
Repeated administration of the substituted amphetamine p-methoxyamphetamine produces reductions in cortical 5-HT transporter binding but not 5-HT content, unlike 3,4-methylenedioxyamethamphetamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamines; Animals; Binding, Competitive; Brain Chemistry; Cerebral Cortex; Chromatography, High Pressure Liquid; Dopamine; Dose-Response Relationship, Drug; Electrochemistry; Hallucinogens; Hydroxyindoleacetic Acid; Male; N-Methyl-3,4-methylenedioxyamphetamine; Paroxetine; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Synaptic Transmission; Time Factors | 2006 |
Ketamine pretreatment exacerbated 3,4-methylenedioxymethamphetamine-induced central dopamine toxicity.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Drug Synergism; Ketamine; Male; Mice; Mice, Inbred C57BL; N-Methyl-3,4-methylenedioxyamphetamine; Serotonin; Substance-Related Disorders | 2008 |
Mice lacking multidrug resistance protein 1a show altered dopaminergic responses to methylenedioxymethamphetamine (MDMA) in striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; 3,4-Methylenedioxyamphetamine; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Corpus Striatum; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Mice; Mice, Inbred Strains; Mice, Knockout; N-Methyl-3,4-methylenedioxyamphetamine; Serotonin | 2010 |
Atypical development of behavioural sensitization to 3,4-methylenedioxymethamphetamine (MDMA, 'Ecstasy') in adolescent rats and its expression in adulthood: role of the MDMA chirality.
Topics: 3,4-Dihydroxyphenylacetic Acid; Age Factors; Animals; Animals, Newborn; Brain; Chromatography, High Pressure Liquid; Dopamine; Hallucinogens; Hydroxyindoleacetic Acid; Illicit Drugs; Male; Mice; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Sprague-Dawley; Serotonin; Stereoisomerism | 2010 |
Increased effects of 3,4-methylenedioxymethamphetamine (ecstasy) in a rat model of depression.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Arousal; Body Temperature Regulation; Brain; Cerebral Cortex; Depression; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Fever; Hallucinogens; Heart Rate; Hydroxyindoleacetic Acid; Male; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Rats, Sprague-Dawley; Serotonin; Serotonin Agents | 2011 |
Endocrine and neurochemical effects of 3,4-methylenedioxymethamphetamine and its stereoisomers in rhesus monkeys.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Central Nervous System Stimulants; Corpus Striatum; Dopamine; Extracellular Space; Female; Hallucinogens; Homovanillic Acid; Macaca mulatta; Microdialysis; N-Methyl-3,4-methylenedioxyamphetamine; Prolactin; Serotonin; Stereoisomerism; Structure-Activity Relationship | 2010 |
Adolescent pre-exposure to ethanol or MDMA prolongs the conditioned rewarding effects of MDMA.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Animals, Outbred Strains; Cerebral Cortex; Choice Behavior; Conditioning, Psychological; Corpus Striatum; Corticosterone; Dopamine; Drug Administration Schedule; Drug Interactions; Ethanol; Extinction, Psychological; Hippocampus; Hydroxyindoleacetic Acid; Illicit Drugs; Male; Mice; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Reward; Serotonin | 2011 |
Mephedrone, compared with MDMA (ecstasy) and amphetamine, rapidly increases both dopamine and 5-HT levels in nucleus accumbens of awake rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Chromatography, High Pressure Liquid; Dopamine; Hydroxyindoleacetic Acid; Locomotion; Male; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Serotonin | 2011 |
Effect of intermittent exposure to ethanol and MDMA during adolescence on learning and memory in adult mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Corpus Striatum; Dopamine; Ethanol; Hippocampus; Hydroxyindoleacetic Acid; Male; Maze Learning; Memory; Mice; N-Methyl-3,4-methylenedioxyamphetamine; Serotonin; Serotonin Agents | 2012 |
Assessment of the abuse potential of MDMA in the conditioned place preference paradigm: role of CB1 receptors.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Brain; Conditioning, Operant; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Hallucinogens; Homovanillic Acid; Male; Maze Learning; Mice; Mice, Knockout; N-Methyl-3,4-methylenedioxyamphetamine; Receptor, Cannabinoid, CB1; Reinforcement, Psychology; Substance-Related Disorders; Time Factors | 2013 |
Contribution of dopamine to mitochondrial complex I inhibition and dopaminergic deficits caused by methylenedioxymethamphetamine in mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aconitate Hydratase; alpha-Methyltyrosine; Animals; Body Temperature; Corpus Striatum; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Electron Transport Complex I; Gene Expression Regulation; Hallucinogens; Homovanillic Acid; Levodopa; Male; Mice; Mice, Inbred C57BL; N-Methyl-3,4-methylenedioxyamphetamine; Piperazines; Tyrosine 3-Monooxygenase | 2015 |
The acute toxic and neurotoxic effects of 3,4-methylenedioxymethamphetamine are more pronounced in adolescent than adult mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Age Factors; Animals; Body Weight; Central Nervous System Stimulants; Corpus Striatum; Dopamine; Hyperthermia; Male; Mice; N-Methyl-3,4-methylenedioxyamphetamine; Prefrontal Cortex | 2020 |