3,4-dihydroxyphenylacetic acid has been researched along with morphine in 115 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 45 (39.13) | 18.7374 |
| 1990's | 38 (33.04) | 18.2507 |
| 2000's | 24 (20.87) | 29.6817 |
| 2010's | 7 (6.09) | 24.3611 |
| 2020's | 1 (0.87) | 2.80 |
| Authors | Studies |
|---|---|
| Di Chiara, G; Gessa, GL; Longoni, R; Mulas, A; Porceddu, ML; Vargiu, L | 1 |
| Nowycky, MC; Roth, RH; Walters, JR | 1 |
| Bläsig, J; Gramsch, C; Herz, A | 1 |
| De Montis, GM; Di Lorenzo, C; Olianas, MC; Tagliamonte, A | 1 |
| Korf, J; Westerink, BH | 2 |
| Cebeira, M; Fernández-Ruiz, JJ; Hernández, ML; Navarro, M; Ramos, JA; Rodriguez de Fonseca, F | 1 |
| Eaton, MJ; Lookingland, KJ; Manzanares, J; Moore, KE; Tian, Y | 1 |
| Carlson, JN; Glick, SD; Keller, RW; Merski, C; Steindorf, S; Wang, S | 1 |
| Hoganson, DA; Hughes, RA; Sufka, KJ | 1 |
| Blanc, G; Glowinski, J; Tassin, JP; Vezina, P | 1 |
| Ishikawa, K; Kogure, M; Kubo, T; Shibanoki, S | 1 |
| Hoebel, BG; Mark, GP; Pothos, E; Rada, P | 1 |
| Glick, SD; Keller, RW; Maisonneuve, IM | 1 |
| Fujimura, H; Niwa, M; Nose, T; Nozaki, M; Tsurumi, K | 1 |
| Daval, G; Fattaccini, CM; Gozlan, H; Hamon, M; Spampinato, U | 1 |
| Ahtee, L; Attila, LM; Carlson, KR; Haikala, H | 1 |
| Iyengar, S; Kim, HS; Marien, MR; McHugh, D; Wood, PL | 1 |
| De Montis, GM; Devoto, P; Meloni, D; Porcella, A; Saba, P; Tagliamonte, A | 1 |
| Esposito, E; Romandini, S; Samanin, R; Spampinato, U | 1 |
| Kuschinsky, K; Walter, S | 1 |
| Enz, A; Hefti, F; Melamed, E | 1 |
| Cosi, C; Iyengar, S; Kim, HS; Wood, PL | 1 |
| Artinián, J; Cancela, LM; Fulginiti, S | 1 |
| Clark, JT; Gabriel, SM; Kalra, PS; Kalra, SP; Simpkins, JW | 1 |
| Duffy, P; Kalivas, PW | 1 |
| Misawa, M; Suzuki, T; Takahashi, K; Yoshii, T | 1 |
| Di Chiara, G; Imperato, A | 1 |
| Damsma, G; de Vries, JB; Rollema, H; Tuntler, J; Westerink, BH | 1 |
| Kamata, K; Kameyama, T; Noma, S; Ogawa, K | 1 |
| Iyengar, S; Kim, HS; Wood, PL | 1 |
| Furukawa, H; Hiramatsu, M; Kameyama, T; Nabeshima, T | 1 |
| Algeri, S; Conforti, I; Dal Toso, G; De Simoni, MG; Giglio, R | 1 |
| Havemann, U; Kuschinsky, K; Melzacka, M; Nesselhut, T; Vetulani, J | 1 |
| Lookingland, KJ; Moore, KE | 1 |
| Fekete, MI; Kanyicska, B; Stark, E; Szentendrei, T | 1 |
| Stanley, M; Wilk, S | 1 |
| Tabakoff, B; Urwyler, S | 1 |
| Ishikawa, K; McGaugh, JL; Shibanoki, S | 1 |
| Bardon, T; Ruckebusch, M | 1 |
| Battaini, F; Kobayashi, H; Reggiani, A; Spano, P; Trabucchi, M | 1 |
| Allikmets, LKh; Nurk, AM | 1 |
| Hoffman, PL; Tabakoff, B; Urwyler, S | 1 |
| Richard, JW; Wood, PL | 1 |
| Genç, E; Havemann, U; Kuschinsky, K; Tzoneva-Tyutyulkova, N | 1 |
| Moleman, P; van Valkenburg, CF; vd Krogt, JA | 1 |
| Alper, RH; Demarest, KT; Moore, KE | 1 |
| Algeri, S; De Simoni, MG; Guardabasso, V; Misterek, K | 1 |
| Spaan, SJ; Westerink, BH | 1 |
| Genç, E; Havemann, U; Kuschinsky, K; Winkler, M | 1 |
| Barbaccia, ML; Bosio, A; Lucchi, L; Spano, PF; Trabucchi, M | 1 |
| McMillen, BA | 1 |
| Coscia, CJ; Galloway, MP; Roth, BL | 1 |
| Barraclough, CA; He, JR; Molnar, J | 1 |
| Ashby, CR; Eberle, WF; Strecker, RE | 1 |
| Ahtee, L; Honkanen, A; Piepponen, TP | 1 |
| Alcaraz, C; Martinez-Piñero, MG; Milanés, MV; Vargas, ML | 1 |
| Misawa, M; Onodera, K; Suzuki, T; Takamori, K | 1 |
| Ahtee, L; Airio, J; Attila, M; Leikola-Pelho, T | 1 |
| Funada, M; Misawa, M; Nagase, H; Narita, M; Suzuki, T | 2 |
| Funada, M; Misawa, M; Suzuki, T | 1 |
| Anagnostakis, Y; Spyraki, C | 1 |
| Glick, SD; Johnson, DW | 2 |
| Bardo, MT; Kolta, MG | 1 |
| Funada, M; Misawa, M; Suzuki, T; Tsuda, M | 1 |
| Kamei, J; Saitoh, A | 1 |
| De Natale, G; Desole, MS; Enrico, P; Esposito, G; Fresu, L; Miele, E; Miele, M; Migheli, R; Mura, MA | 1 |
| Lin, JY; Pan, JT | 1 |
| Barden, N; Holsboer, F; Spanagel, B; Stöhr, T | 1 |
| Di Giulio, AM; Gorio, A; Malosio, ML; Vergani, L | 1 |
| Ahtee, L; Piepponen, TP | 1 |
| Javelle, N; Lambás-Señas, L; Renaud, B | 1 |
| De Natale, G; Desole, MS; Enrico, P; Esposito, G; Fresu, L; Miele, E; Miele, M; Mura, MA | 1 |
| Glick, SD; Maisonneuve, IM; Pearl, SM | 1 |
| Huang, NK; Tseng, CJ; Tung, CS; Wong, CS | 1 |
| Borg, PJ; Taylor, DA | 1 |
| Cousins, M; Ghosh, S; Grasing, K; Patel, AH | 1 |
| De Natale, G; Desole, MS; Enrico, P; Esposito, G; Miele, E; Miele, M; Migheli, R; Mura, MA; Serra, P | 1 |
| Ahtee, L; Jonker, D; Mikkola, JA; Piepponen, TP; Ruotsalainen, M | 1 |
| Catalani, A; Di Giannuario, A; Loizzo, A; Pieretti, S | 1 |
| Glick, SD; Maisonneuve, IM | 1 |
| Fuertes, G; Laorden, ML; Milanés, MV | 1 |
| Laorden, ML; Milanés, MV | 1 |
| Ho, IK; Tokuyama, S; Yamamoto, T | 1 |
| Di Giannuario, A; Pieretti, S | 1 |
| Ahtee, L; Honkanen, A; Kiianmaa, K; Mikkola, JA; Piepponen, TP | 1 |
| Glick, SD; Maisonneuve, IM; Warner, LM | 1 |
| Blanc, G; Cotecchia, S; Darracq, L; Drouin, C; Glowinski, J; Tassin, JP; Trovero, F | 1 |
| Bérod, A; Javelle, N; Lambás-Señas, L; Renaud, B | 1 |
| Macedo, TR; Morgadinho, MT; Oliveira, CR; Oliveira, MT; Rego, AC | 1 |
| Cerezo, M; Laorden, ML; Milanés, MV | 1 |
| Buckland, P; Deslandes, PN; Pache, DM; Sewell, RD | 1 |
| Bäckström, P; Hyytiä, P; Kankaanpää, A; Kiianmaa, K; Koistinen, M; Ojanen, S; Tuomainen, P | 1 |
| Aoki, K; Kuzumaki, N; Narita, M; Suzuki, T; Takagi, M | 1 |
| Huang, EY; Liu, TC; Tao, PL | 1 |
| Ahmed, SH; Barbano, MF; Cador, M; Stinus, L | 1 |
| Ahmadiani, A; Alaei, H; Amini, H; Nasimi, A; Rajaei, Z | 1 |
| Felicio, LF; Flório, JC; Miranda-Paiva, CM; Nasello, AG; Oliveira, CA; Yim, AJ | 1 |
| Ahtee, L; Airavaara, M; Mijatovic, J; Piepponen, TP; Saarma, M; Vihavainen, T | 1 |
| Huang, EY; Liang, KW; Sung, WY; Tao, PL; Wu, YT | 1 |
| Ali, SF; Lourenço, E; Macedo, TR; Milhazes, N; Morgadinho, T; Pereira, FC; Ribeiro, CF | 1 |
| Chen, Z; Gong, YX; Lv, M; Shi, H; Wei, EQ; Zeng, QL; Zhu, YP; Zhu, YY | 1 |
| Glick, SD; Maisonneuve, IM; Shulan, JM; Taraschenko, OD | 1 |
| Li, J; Lu, XQ; Su, RB; Wei, XL; Wu, N; Zheng, JQ | 1 |
| Cui, CL; Guo, CY; Han, JS; Lee, DY; Ma, YY; Meng, L | 1 |
| Barson, JR; Hoebel, BG; Leibowitz, SF; Rada, P | 1 |
| Basaran, NF; Buyukuysal, RL; Cavun, S; Millington, WR | 1 |
| González-Cuello, A; Hidalgo, JM; Laorden, ML; Lasheras, C; Meca, N; Milanés, MV; Mora, L | 1 |
| Goudreau, JL; Kennedy, T; Lookingland, KJ; Pappas, SS | 1 |
| García-Pérez, D; Laorden, ML; Milanés, MV; Núñez, C; Sáez-Belmonte, F | 1 |
| Havlickova, T; Jerabek, P; Kacer, P; Krsiak, M; Sustkova-Fiserova, M | 1 |
| García-Pérez, D; Laorden, ML; López-Bellido, R; Milanés, MV; Núñez, C; Rodríguez, RE | 1 |
| Hassan, Z; Müller, CP; Murugaiyah, V; Yusoff, NHM | 1 |
115 other study(ies) available for 3,4-dihydroxyphenylacetic acid and morphine
| Article | Year |
|---|---|
Indirect activation of the DA system as a possible mechanism for the stimulatory effects of narcotic analgesics.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adenylyl Cyclases; Analgesics, Opioid; Animals; Apomorphine; Catalepsy; Caudate Nucleus; Dextroamphetamine; Dopamine; Drug Interactions; Globus Pallidus; Humans; In Vitro Techniques; Injections; Mice; Morphine; Motor Activity; Olfactory Bulb; Rats; Stimulation, Chemical; Substantia Nigra | 1977 |
Dopaminergic neurons: effect of acute and chronic morphine administration on single cell activity and transmitter metabolism.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Dihydroxyphenylalanine; Male; Morphine; Naloxone; Neurons; Rats; Synaptic Transmission; Tyrosine | 1978 |
Changes in striatal dopamine metabolism during precipitated morphine withdrawal.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benzomorphans; Catechol O-Methyltransferase; Corpus Striatum; Dopamine; Homovanillic Acid; Humans; Male; Monoamine Oxidase; Morphine; Naloxone; Probenecid; Rats; Substance Withdrawal Syndrome; Time Factors; Tyramine | 1977 |
Failure of morphine to increase striatal 3,4-dihydroxyphenylacetic acid in fasted rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Fasting; Male; Morphine; Naloxone; Phenylacetates; Rats; Stimulation, Chemical | 1978 |
Acidic dopamine metabolites in cortical areas of the rat brain: localization and effects of drug.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Apomorphine; Cerebral Cortex; Clozapine; Corpus Striatum; Haloperidol; Homovanillic Acid; Male; Morphine; Olfactory Bulb; Oxotremorine; Phenylacetates; Probenecid; Rats; Sulpiride; Thioridazine | 1976 |
Comparison of effects of drugs on dopamine metabolism in the substantia nigra and the corpus striatum of rat brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Brain Chemistry; Chloral Hydrate; Corpus Striatum; Dopamine; Haloperidol; Homovanillic Acid; Male; Morphine; Oxotremorine; Pargyline; Phenylacetates; Probenecid; Promethazine; Rats; Receptors, Dopamine; Substantia Nigra | 1976 |
Modifications of striatal D2 dopaminergic postsynaptic sensitivity during development of morphine tolerance-dependence in mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adenylyl Cyclases; Animals; Brain Chemistry; Corpus Striatum; Cyclic AMP; Dopamine; Kinetics; Male; Mice; Morphine; Morphine Dependence; Motor Activity; Naloxone; Receptors, Dopamine D1; Receptors, Dopamine D2; Synapses | 1992 |
Characterization of opioid receptor-mediated regulation of incertohypothalamic dopamine neurons: lack of evidence for a role of 5-hydroxytryptaminergic neurons in mediating the stimulatory effects of morphine.
Topics: 3,4-Dihydroxyphenylacetic Acid; 5,6-Dihydroxytryptamine; Animals; Catheterization; Creatinine; Dopamine; Female; Hypothalamus; Hypothalamus, Middle; Injections, Intraventricular; Male; Morphine; Neurons; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Serotonin | 1992 |
Neurochemical predisposition to self-administer morphine in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cerebral Cortex; Corpus Striatum; Female; Homovanillic Acid; Hydroxyindoleacetic Acid; Injections, Intravenous; Morphine; Morphine Dependence; Nucleus Accumbens; Rats; Rats, Inbred Strains; Self Administration; Substantia Nigra | 1992 |
Central monoaminergic changes induced by morphine in hypoalgesic and hyperalgesic strains of domestic fowl.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Monoamines; Brain Chemistry; Chickens; Chromatography, High Pressure Liquid; Hydroxyindoleacetic Acid; Inflammation; Morphine; Pain; Species Specificity | 1992 |
Nicotine and morphine differentially activate brain dopamine in prefrontocortical and subcortical terminal fields: effects of acute and repeated injections.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Dopamine; Dose-Response Relationship, Drug; Injections, Intravenous; Male; Morphine; Motor Activity; Nicotine; Rats; Rats, Inbred Strains | 1992 |
Naloxone affects both pharmacokinetics and pharmacodynamics of morphine. Application of direct correlation analysis.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Corpus Striatum; Homovanillic Acid; Hydroxyindoleacetic Acid; Hypothalamus; Male; Methoxyhydroxyphenylglycol; Morphine; Naloxone; Protein Binding; Rats; Rats, Inbred Strains; Statistics as Topic; Sulfobromophthalein | 1991 |
Systemic morphine simultaneously decreases extracellular acetylcholine and increases dopamine in the nucleus accumbens of freely moving rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcholine; Animals; Choline; Chromatography, High Pressure Liquid; Dialysis; Dopamine; Electrochemistry; Homovanillic Acid; Male; Morphine; Nucleus Accumbens; Rats; Rats, Inbred Strains | 1991 |
Interactions between ibogaine, a potential anti-addictive agent, and morphine: an in vivo microdialysis study.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Catecholamines; Cerebral Cortex; Chromatography, High Pressure Liquid; Corpus Striatum; Dialysis; Dopamine; Drug Interactions; Female; Homovanillic Acid; Ibogaine; Morphine; Motor Activity; Nucleus Accumbens; Rats; Rats, Inbred Strains; Self Administration; Stereotaxic Techniques | 1991 |
Effects of butorphanol and its metabolites on the levels of monoamines and their metabolites in the rat brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Amines; Brain; Butorphanol; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Morphinans; Morphine; Norepinephrine; Pentazocine; Rats; Rats, Inbred Strains; Serotonin | 1985 |
Dopamine receptor subsensitivity in the substantia nigra after chronic morphine treatment in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Autoradiography; Behavior, Animal; Chromatography, High Pressure Liquid; Dopamine; Hydroxyindoleacetic Acid; Injections, Subcutaneous; Male; Morphine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Serotonin; Substantia Nigra | 1988 |
Changes in brain monoamine metabolism during withdrawal from chronic oral self-administration of morphine and in response to a morphine challenge in the withdrawn state.
Topics: 3,4-Dihydroxyphenylacetic Acid; Administration, Oral; Animals; Biogenic Amines; Brain; Dopamine; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Morphine; Rats; Rats, Inbred Strains; Self Administration; Substance Withdrawal Syndrome | 1989 |
Modulation of mesolimbic dopaminergic projections by beta-endorphin in the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; beta-Endorphin; Cerebral Ventricles; Corpus Striatum; Dopamine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Homovanillic Acid; Injections, Intraventricular; Kinetics; Male; Morphine; Nucleus Accumbens; Rats; Rats, Inbred Strains; Reference Values; Septal Nuclei | 1989 |
Resistance to extrapyramidal effects of opiates in rats chronically treated with SCH 23390.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benzazepines; Catalepsy; Corpus Striatum; Drug Tolerance; Male; Morphine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1 | 1989 |
Changes of serotonin and dopamine metabolism in various forebrain areas of rats injected with morphine either systemically or in the raphe nuclei dorsalis and medianus.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Cerebral Cortex; Corpus Striatum; Diencephalon; Dopamine; Fenclonine; Hippocampus; Homovanillic Acid; Hydroxyindoleacetic Acid; In Vitro Techniques; Male; Morphine; Nucleus Accumbens; Raphe Nuclei; Rats; Serotonin | 1985 |
Conditioning of morphine-induced locomotor activity and stereotyped behaviour in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Conditioning, Classical; Dopamine; Male; Morphine; Motor Activity; Rats; Rats, Inbred Strains; Stereotyped Behavior | 1989 |
Partial lesions of the nigrostriatal pathway in the rat. Acceleration of transmitter synthesis and release of surviving dopaminergic neurones by drugs.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; gamma-Aminobutyric Acid; Haloperidol; Homovanillic Acid; Hydroxydopamines; Male; Morphine; Neurons; Neurotransmitter Agents; Oxidopamine; Rats; Rats, Inbred Strains; Substantia Nigra | 1985 |
The endogenous kappa agonist, dynorphin(1-13), does not alter basal or morphine-stimulated dopamine metabolism in the nigrostriatal pathway of the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Corticosterone; Dopamine; Dynorphins; Homovanillic Acid; Male; Morphine; Peptide Fragments; Rats; Rats, Inbred Strains; Substantia Nigra | 1987 |
Opioid influence on some aspects of stereotyped behavior induced by repeated amphetamine treatment.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Apomorphine; beta-Endorphin; Corpus Striatum; Dopamine; Male; Morphine; Naloxone; Narcotics; Nucleus Accumbens; Rats; Rats, Inbred Strains; Reference Values; Stereotyped Behavior | 1988 |
Chronic morphine and testosterone treatment. Effects on sexual behavior and dopamine metabolism in male rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Dopamine; Homovanillic Acid; Male; Morphine; Orchiectomy; Penile Erection; Rats; Rats, Inbred Strains; Reflex; Sexual Behavior, Animal; Testosterone | 1988 |
Effects of daily cocaine and morphine treatment on somatodendritic and terminal field dopamine release.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Brain; Cocaine; Corpus Striatum; Dopamine; Male; Mesencephalon; Morphine; Nucleus Accumbens; Potassium; Rats; Rats, Inbred Strains | 1988 |
[Changes in CNS catecholamine levels in tolerance to morphine-induced central excitation in mice].
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Catecholamines; Drug Tolerance; Male; Mice; Morphine; Motor Activity; Stimulation, Chemical | 1987 |
Preferential stimulation of dopamine release in the nucleus accumbens by opiates, alcohol, and barbiturates: studies with transcerebral dialysis in freely moving rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Dialysis; Dopamine; Ethanol; Homovanillic Acid; Kinetics; Male; Morphine; Nucleus Accumbens; Pentobarbital; Rats; Rats, Inbred Strains; Septal Nuclei | 1986 |
The use of tetrodotoxin for the characterization of drug-enhanced dopamine release in conscious rats studied by brain dialysis.
Topics: 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Corpus Striatum; Dialysis; Dopamine; Haloperidol; Homovanillic Acid; Male; Morphine; Neurotoxins; Nucleus Accumbens; Piperazines; Pyridinium Compounds; Rats; Rats, Inbred Strains; Septal Nuclei; Tetrodotoxin | 1987 |
Effects of apomorphine on morphine analgesia during the state of dopaminergic supersensitivity after chronic treatment with haloperidol.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Behavior, Animal; Brain Chemistry; Corpus Striatum; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Haloperidol; Male; Morphine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Substantia Nigra; Time Factors | 1986 |
Opiate actions on mesocortical dopamine metabolism in the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Cerebral Cortex; Corpus Striatum; Dopamine; Homovanillic Acid; Male; Morphine; Olfactory Bulb; Rats; Rats, Inbred Strains | 1986 |
Effects of phencyclidine in combination with morphine on the levels of met-enkephalin, dopamine, DOPAC and HVA in discrete brain areas of mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Cerebral Cortex; Corpus Striatum; Dopamine; Drug Interactions; Enkephalin, Methionine; Homovanillic Acid; Male; Mesencephalon; Mice; Mice, Inbred Strains; Morphine; Phencyclidine; Phenylacetates | 1985 |
Cross tolerance between ketamine and morphine to some pharmacological and biochemical effects.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analgesics; Animals; Brain Chemistry; Corpus Striatum; Drug Tolerance; Homovanillic Acid; Ketamine; Limbic System; Male; Morphine; Rats; Reflex; Sleep | 1985 |
Pharmacokinetics of morphine in striatum and nucleus accumbens: relationship to pharmacological actions.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Electromyography; Kinetics; Male; Morphine; Morphine Derivatives; Muscle Contraction; Nucleus Accumbens; Rats; Rats, Inbred Strains; Septal Nuclei; Time Factors | 1985 |
Acute effects of morphine on neurochemical estimates of activity of incertohypothalamic dopaminergic neurons in the male rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Dopamine; Electrochemistry; Hypothalamus; Male; Methyltyrosines; Morphine; Naltrexone; Neural Pathways; Neurons; Rats; Rats, Inbred Strains; Time Factors | 1985 |
Loss of sensitivity to morphine induced by prolonged ACTH treatment.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenocorticotropic Hormone; Analgesia; Animals; Corpus Striatum; Corticosterone; Dexamethasone; Dopamine; Growth Hormone; Male; Morphine; Motor Activity; Rats; Reaction Time; Time Factors | 1984 |
The differential effects of morphine, oxotremorine and antipsychotic drugs on DOPAC concentrations in rat brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antipsychotic Agents; Brain Chemistry; Corpus Striatum; Dose-Response Relationship, Drug; Male; Morphine; Olfactory Bulb; Oxotremorine; Phenylacetates; Rats; Time Factors | 1980 |
Stimulation of dopamine synthesis and release by morphine and D-ala2-D-leu5-enkephalin in the mouse striatum in vivo.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benztropine; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Endorphins; Enkephalin, Leucine-2-Alanine; Enkephalins; Male; Mice; Morphine; Tyrosine 3-Monooxygenase | 1981 |
Direct correlation between level of morphine and its biochemical effect on monoamine systems in mouse brain. Evidence for involvement of dopaminergic neurons in the pharmacological action of acute morphine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Amines; Brain; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Kinetics; Male; Mice; Mice, Inbred ICR; Morphine; Norepinephrine; Serotonin | 1983 |
Changes in 5-HIAA and 5-HT levels in lumbar CSF following morphine administration to conscious dogs.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Dogs; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Injections, Spinal; Morphine; Serotonin | 1984 |
Genotype-dependent sensitivity to morphine: role of different opiate receptor populations.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Genotype; Hydroxydopamines; Kinetics; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Morphine; Organ Specificity; Receptors, Opioid; Species Specificity; Substrate Specificity | 1980 |
[Effect of chronic administration of lithium chloride on the development of dopamine receptor sensitivity during morphine withdrawal in rats].
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Chlorides; Corpus Striatum; Dopamine; Homovanillic Acid; Humans; Lithium; Lithium Chloride; Male; Morphine; Rats; Receptors, Dopamine; Substance Withdrawal Syndrome; Time Factors | 1981 |
Alterations in opiate receptor function after chronic ethanol exposure.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alcoholism; Animals; Caudate Nucleus; Corpus Striatum; Dihydromorphine; Dihydroxyphenylalanine; Dopamine; Humans; Male; Mice; Mice, Inbred C57BL; Morphine; Receptors, Opioid | 1982 |
Morphine and nigrostriatal function in the rat and mouse: the role of nigral and striatal opiate receptors.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Homovanillic Acid; Male; Mice; Morphine; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid; Species Specificity; Substantia Nigra | 1982 |
Motility, rigidity and turnover of dopamine in the striatum after administration of morphine to rats: a re-evaluation of their mechanisms.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Kainic Acid; Male; Morphine; Motor Activity; Muscle Rigidity; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Opioid | 1983 |
Effects of morphine on dopamine metabolism in rat striatum and limbic structures in relation to the activity of dopaminergic neurones.
Topics: 3,4-Dihydroxyphenylacetic Acid; 4-Butyrolactone; Animals; Corpus Striatum; Dopamine; Homovanillic Acid; Limbic System; Male; Morphine; Neurons; Rats; Rats, Inbred Strains | 1984 |
Morphine differentially alters synthesis and turnover of dopamine in central neuronal systems.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Limbic System; Male; Median Eminence; Morphine; Naloxone; Neurons; Nucleus Accumbens; Pituitary Gland, Posterior; Rats | 1980 |
Similarities and differences between D-ALA2 MET5 enkephalin amide and morphine in the induction of tolerance to their effects on catalepsy and on dopamine metabolism in the rat brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Catalepsy; Corpus Striatum; Dopamine; Drug Tolerance; Enkephalin, Methionine; Humans; Limbic System; Male; Morphine; Rats; Substantia Nigra | 1982 |
On the significance of endogenous 3-methoxytyramine for the effects of centrally acting drugs on dopamine release in the rat brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; 4-Butyrolactone; Animals; Apomorphine; Benztropine; Brain; Chlorpromazine; Dextroamphetamine; Dopamine; Female; Haloperidol; Homovanillic Acid; Kinetics; Morphine; Nomifensine; Oxotremorine; Rats; Rats, Inbred Strains; Reserpine | 1982 |
Effects of striatal lesions with kainic acid on morphine-induced "catatonia" and increase of striatal dopamine turnover.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Catatonia; Corpus Striatum; Dopamine; Electromyography; Humans; Kainic Acid; Male; Morphine; Motor Activity; Motor Neurons; Pyrrolidines; Rats; Rats, Inbred Strains | 1981 |
Neuronal mechanisms regulating ethanol effects on the dopaminergic system.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alcoholism; Animals; Dopamine; Ethanol; Haloperidol; Humans; Male; Morphine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Sulpiride | 1982 |
On the mechanism of morphine action on rat striatal dopamine metabolsim.
Topics: 3,4-Dihydroxyphenylacetic Acid; 4-Butyrolactone; Animals; Apomorphine; Corpus Striatum; Dopamine; Female; Haloperidol; In Vitro Techniques; Morphine; Naloxone; Rats | 1980 |
The effects of morphine on catecholamine metabolism during postnatal development.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenal Medulla; Aging; Animals; Catecholamines; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Epinephrine; Morphine; Norepinephrine; Rats | 1980 |
Effect of morphine on hypothalamic tyrosine hydroxylase mRNA levels in dopaminergic neurons and on preoptic DOPAC levels measured by microdialysis.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Diencephalon; Dopamine; Hydroxyindoleacetic Acid; Hypothalamus; Injections, Subcutaneous; Microdialysis; Morphine; Neurons; Preoptic Area; Prolactin; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tyrosine 3-Monooxygenase | 1994 |
Extracellular dopamine and its metabolites in the nucleus accumbens of Fischer and Lewis rats: basal levels and cocaine-induced changes.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Cocaine; Dopamine; Extracellular Space; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Morphine; Nucleus Accumbens; Rats; Rats, Inbred F344; Rats, Inbred Lew | 1995 |
Morphine-stimulated metabolism of striatal and limbic dopamine is dissimilarly sensitized in rats upon withdrawal from chronic morphine treatment.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Homovanillic Acid; Limbic System; Morphine; Motor Activity; Nucleus Accumbens; Rats; Rats, Wistar; Stereotyped Behavior; Substance Withdrawal Syndrome | 1994 |
Catecholaminergic mediation of morphine-induced activation of pituitary-adrenocortical axis in the rat: implication of alpha- and beta-adrenoceptors.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic beta-Agonists; Adrenocorticotropic Hormone; Animals; Corticosterone; Corticotropin-Releasing Hormone; Dopamine; gamma-Aminobutyric Acid; Hypothalamo-Hypophyseal System; Male; Morphine; Norepinephrine; Pituitary-Adrenal System; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Reserpine | 1994 |
Effects of the histaminergic system on the morphine-induced conditioned place preference in mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benzazepines; Benzothiazoles; Conditioning, Operant; Dihydroxyphenylalanine; Dopamine; Dose-Response Relationship, Drug; Histamine; Histamine H2 Antagonists; Histidine; Histidine Decarboxylase; Homovanillic Acid; Limbic System; Male; Methylhistidines; Mice; Mice, Inbred Strains; Morphine; Phenoxypropanolamines; Piperidines; Prosencephalon; Thiazoles | 1995 |
Withdrawal from repeated morphine sensitizes mice to the striatal dopamine release enhancing effect of acute morphine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benzazepines; Dopamine; Homovanillic Acid; In Vitro Techniques; Male; Methyltyrosines; Mice; Morphine; Receptors, Dopamine; Spiperone; Visual Cortex | 1994 |
Involvement of delta-opioid receptors in the effects of morphine on locomotor activity and the mesolimbic dopaminergic system in mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analgesics; Animals; Dopamine; Homovanillic Acid; Limbic System; Male; Mice; Mice, Inbred Strains; Morphine; Motor Activity; Naltrexone; Narcotic Antagonists; Postural Balance; Reaction Time; Receptors, Opioid, delta | 1993 |
Blockade of morphine reward through the activation of kappa-opioid receptors in mice.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; 3,4-Dihydroxyphenylacetic Acid; Analgesics; Animals; Apomorphine; Conditioning, Operant; Dopamine; Dynorphins; Homovanillic Acid; Injections, Subcutaneous; Limbic System; Male; Mice; Mice, Inbred Strains; Morphine; Motivation; Naltrexone; Peptide Fragments; Prosencephalon; Pyrrolidines; Receptors, Opioid, kappa; Reward | 1993 |
The role of dopamine D1-receptors in morphine-induced hyperlocomotion in mice.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Dopamine; Dopamine Agents; Electrochemistry; Ergolines; Homovanillic Acid; Injections, Intraventricular; Male; Mice; Mice, Inbred Strains; Morphine; Motor Activity; Quinpirole; Receptors, Dopamine D1 | 1994 |
Effect of morphine applied by intrapallidal microdialysis on the release of dopamine in the nucleus accumbens.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Globus Pallidus; Homovanillic Acid; Male; Microdialysis; Microinjections; Morphine; Nucleus Accumbens; Osmolar Concentration; Rats; Rats, Sprague-Dawley | 1994 |
Handling and/or saline injections alter basal and morphine-evoked changes in dopamine metabolites in the striatum and nucleus accumbens of rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Dopamine; Female; Handling, Psychological; Homovanillic Acid; Injections; Microdialysis; Morphine; Neostriatum; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Solutions; Stress, Psychological | 1994 |
Dopamine release and metabolism in nucleus accumbens and striatum of morphine-tolerant and nontolerant rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Catecholamines; Corpus Striatum; Dopamine; Drug Tolerance; Extracellular Space; Female; Homovanillic Acid; Microdialysis; Morphine; Motor Activity; Nucleus Accumbens; Rats; Rats, Sprague-Dawley | 1993 |
Opioid modulation of amphetamine-stimulated dopamine release and concentration in rat striatal slices.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Dihydroxyphenylalanine; Dopamine; Hydrazines; In Vitro Techniques; Male; Morphine; Naltrexone; Narcotics; Neostriatum; Rats; Rats, Sprague-Dawley | 1993 |
Blockade of morphine-induced place preference by diazepam in mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Chromatography, High Pressure Liquid; Conditioning, Psychological; Diazepam; Dopamine; Drug Interactions; Flumazenil; GABA Modulators; Homovanillic Acid; Injections, Intraperitoneal; Male; Mice; Morphine; Narcotic Antagonists | 1995 |
Modification of the effects of 7-OH-DPAT, a dopamine D3-receptor agonist, on morphine-induced hyperlocomotion by diabetes.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Chromatography, High Pressure Liquid; Diabetes Mellitus, Experimental; Dopamine; Dopamine Agonists; Dose-Response Relationship, Drug; Homovanillic Acid; Male; Mice; Mice, Inbred ICR; Morphine; Motor Activity; Nucleus Accumbens; Olfactory Pathways; Receptors, Dopamine D2; Receptors, Dopamine D3; Reference Values; Tetrahydronaphthalenes | 1996 |
Effects of morphine treatment and withdrawal on striatal and limbic monoaminergic activity and ascorbic acid oxidation in the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amines; Animals; Ascorbic Acid; Corpus Striatum; Dopamine; gamma-Aminobutyric Acid; Male; Morphine; Prosencephalon; Rats; Rats, Wistar; Substance Withdrawal Syndrome | 1996 |
Prolonged pertussis toxin treatment affects morphine's action on tuberoinfundibular dopaminergic neuron activity and on prolactin secretion.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cerebral Ventricles; Delayed-Action Preparations; Dopamine; Drug Interactions; Estradiol; Female; Hypothalamus, Middle; Injections, Intraventricular; Kinetics; Median Eminence; Morphine; Neurons; Ovariectomy; Pertussis Toxin; Prolactin; Rats; Rats, Sprague-Dawley; Time Factors; Virulence Factors, Bordetella | 1996 |
Morphine-induced locomotor and neurochemical stimulation is enhanced in transgenic mice with impaired glucocorticoid receptor function.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenocorticotropic Hormone; Animals; Brain Chemistry; Corticosterone; Dopamine; Dose-Response Relationship, Drug; Limbic System; Male; Mice; Mice, Transgenic; Morphine; Motor Activity; Narcotics; Rats; Receptors, Glucocorticoid; Stimulation, Chemical | 1996 |
Exposure to perinatal morphine promotes developmental changes in rat striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Dopamine; Enkephalin, Methionine; Enkephalins; Female; In Situ Hybridization; Lactation; Male; Morphine; Narcotics; Neostriatum; Neurons; Pregnancy; Prenatal Exposure Delayed Effects; Protein Precursors; Rats; Rats, Sprague-Dawley; Receptors, Opioid; RNA, Messenger; Serotonin; Substance P; Synapses; Synapsins; Time Factors; Tyrosine 3-Monooxygenase | 1996 |
Effects of selective opioid receptor antagonists on morphine-induced changes in striatal and limbic dopamine metabolism.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Homovanillic Acid; Injections, Intraperitoneal; Injections, Intraventricular; Limbic System; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Pain Threshold; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, mu | 1995 |
Monoamine metabolism in the locus coeruleus measured concurrently with behavior during opiate withdrawal: an in vivo microdialysis study in freely moving rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analgesics, Opioid; Animals; Behavior, Animal; Biogenic Monoamines; Hydroxyindoleacetic Acid; Locus Coeruleus; Male; Microdialysis; Monoamine Oxidase Inhibitors; Morphine; Motor Activity; Naltrexone; Narcotic Antagonists; Pargyline; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome | 1997 |
Effect of morphine on striatal dopamine metabolism and ascorbic and uric acid release in freely moving rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Ascorbic Acid; Dopamine; Homovanillic Acid; Male; Microdialysis; Morphine; Narcotics; Neostriatum; Rats; Rats, Wistar; Uric Acid | 1997 |
Prior morphine exposure enhances ibogaine antagonism of morphine-induced dopamine release in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Corpus Striatum; Dopamine; Female; Homovanillic Acid; Ibogaine; Kinetics; Microdialysis; Morphine; Nucleus Accumbens; Rats; Rats, Sprague-Dawley | 1996 |
Effects of acute and chronic morphine on DOPAC and glutamate at subcortical DA terminals in awake rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analgesics, Opioid; Animals; Cerebral Cortex; Corpus Striatum; Dopamine; Drug Evaluation, Preclinical; Glutamic Acid; Male; Microdialysis; Morphine; Naloxone; Nerve Endings; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Time Factors | 1997 |
Involvement of mu- and delta-opioid receptors in the effects of systemic and locally perfused morphine on extracellular levels of dopamine, DOPAC and HVA in the nucleus accumbens of the halothane-anaesthetized rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analgesics, Opioid; Analysis of Variance; Anesthetics, Inhalation; Animals; Chromatography, High Pressure Liquid; Dopamine; Drug Interactions; Halothane; Homovanillic Acid; Injections, Intravenous; Male; Microdialysis; Morphine; Naloxone; Narcotic Antagonists; Nucleus Accumbens; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, mu | 1997 |
Different effects of opiate withdrawal on dopamine turnover, uptake, and release in the striatum and nucleus accumbens.
Topics: 3,4-Dihydroxyphenylacetic Acid; 4-Aminopyridine; Animals; Corpus Striatum; Dopamine; Male; Morphine; Narcotics; Nucleus Accumbens; Potassium; Rats; Rats, Wistar; Substance Withdrawal Syndrome; Time Factors | 1998 |
Effect of naloxone on morphine-induced changes in striatal dopamine metabolism and glutamate, ascorbic acid and uric acid release in freely moving rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analgesics, Opioid; Animals; Ascorbic Acid; Corpus Striatum; Dopamine; Glutamic Acid; Homovanillic Acid; Hydroxyindoleacetic Acid; Locomotion; Male; Microdialysis; Morphine; Naloxone; Narcotic Antagonists; Rats; Rats, Wistar; Substantia Nigra; Uric Acid | 1998 |
Characterization of the decrease of extracellular striatal dopamine induced by intrastriatal morphine administration.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benzomorphans; Dopamine; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Extracellular Space; Homovanillic Acid; Male; Microinjections; Morphine; Narcotic Antagonists; Neostriatum; Rats; Rats, Wistar; Receptors, Opioid, kappa | 1999 |
Orphanin FQ reduces morphine-induced dopamine release in the nucleus accumbens: a microdialysis study in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Dopamine; Dose-Response Relationship, Drug; Homovanillic Acid; Injections, Intraventricular; Male; Microdialysis; Morphine; Narcotic Antagonists; Narcotics; Nociceptin; Nucleus Accumbens; Opioid Peptides; Postural Balance; Psychomotor Performance; Rats; Rats, Wistar; Receptors, Opioid | 1999 |
Attenuation of the reinforcing efficacy of morphine by 18-methoxycoronaridine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Dopamine; Dose-Response Relationship, Drug; Drug Antagonism; Female; Homovanillic Acid; Ibogaine; Microdialysis; Morphine; Narcotics; Nucleus Accumbens; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Self Administration; Time Factors; Visual Cortex | 1999 |
Noradrenergic and dopaminergic activity in the hypothalamic paraventricular nucleus after naloxone-induced morphine withdrawal.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Behavior, Animal; Body Weight; Chronic Disease; Corticosterone; Cyclic AMP; Dopamine; Male; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Narcotics; Norepinephrine; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome | 2000 |
Changes in catecholaminergic pathways innervating the rat heart ventricle during morphine dependence. Involvement Of alpha(1)- and alpha(2)-adrenoceptors.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic alpha-Antagonists; Analgesics, Opioid; Animals; Catecholamines; Dopamine; Heart Ventricles; Male; Morphine; Morphine Dependence; Norepinephrine; Normetanephrine; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Yohimbine | 2000 |
A protein kinase inhibitor, H-7, blocks naloxone-precipitated changes in dopamine and its metabolites in the brains of opioid-dependent rats.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Brain; Butorphanol; Cerebral Cortex; Corpus Striatum; Dopamine; Enzyme Inhibitors; Homovanillic Acid; Injections, Intraperitoneal; Injections, Intraventricular; Limbic System; Male; Mesencephalon; Morphine; Naloxone; Opioid-Related Disorders; Protein Kinase Inhibitors; Protein Kinases; Rats; Rats, Sprague-Dawley | 2000 |
Nociceptin differentially affects morphine-induced dopamine release from the nucleus accumbens and nucleus caudate in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analgesics, Opioid; Animals; Caudate Nucleus; Chromatography, High Pressure Liquid; Dopamine; Dose-Response Relationship, Drug; Electrochemistry; Ethanol; Homovanillic Acid; Male; Microdialysis; Morphine; Nociceptin; Nucleus Accumbens; Opioid Peptides; Rats; Rats, Wistar; Vasodilator Agents | 2000 |
Effects of repeated morphine on cerebral dopamine release and metabolism in AA and ANA rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Drinking; Analgesics, Opioid; Animals; Caudate Nucleus; Dopamine; Homovanillic Acid; Male; Morphine; Nucleus Accumbens; Putamen; Rats | 2000 |
Biphasic dose-related effects of morphine on dopamine release.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analgesics, Opioid; Animals; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Extracellular Space; Female; Homovanillic Acid; Morphine; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Stereotaxic Techniques | 2001 |
Alpha1b-adrenergic receptors control locomotor and rewarding effects of psychostimulants and opiates.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic alpha-Antagonists; Animals; Brain; Central Nervous System Stimulants; Choice Behavior; Cocaine; Crosses, Genetic; Dextroamphetamine; Dopamine; Dopamine Agonists; Male; Mice; Mice, Inbred Strains; Mice, Knockout; Morphine; Motor Activity; Muscarinic Antagonists; Narcotics; Norepinephrine; Prazosin; Receptors, Adrenergic, alpha-1; Receptors, Dopamine D1; Receptors, Dopamine D2; Reward; Substance-Related Disorders; Synaptic Transmission | 2002 |
NO synthase inhibitors attenuate locus coeruleus catecholamine metabolism and behavior induced by morphine withdrawal.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Catecholamines; Enzyme Inhibitors; Locus Coeruleus; Male; Morphine; Motor Activity; Narcotics; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome | 2002 |
Toxic effects of opioid and stimulant drugs on undifferentiated PC12 cells.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cell Survival; Chromatin; Cocaine; Dextroamphetamine; Dopamine; Heroin; L-Lactate Dehydrogenase; Models, Animal; Morphine; Narcotics; PC12 Cells; Pheochromocytoma; Rats; Reactive Oxygen Species | 2002 |
Inhibition of protein kinase C but not protein kinase A attenuates morphine withdrawal excitation of rat hypothalamus-pituitary-adrenal axis.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analgesics, Opioid; Animals; Blood-Brain Barrier; Catecholamines; Chromatography, High Pressure Liquid; Corticosterone; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Hypothalamo-Hypophyseal System; Isoquinolines; Male; Methoxyhydroxyphenylglycol; Morphine; Naphthalenes; Norepinephrine; Paraventricular Hypothalamic Nucleus; Pituitary-Adrenal System; Protein Kinase C; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome; Sulfonamides | 2002 |
Morphine, cocaine and antidepressant induced motivational activity and midbrain dopaminergic neurotransmission.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Central Nervous System Stimulants; Chromatography, High Pressure Liquid; Cocaine; Conditioning, Psychological; Corpus Striatum; Dopamine; Homovanillic Acid; Male; Mesencephalon; Morphine; Motivation; Nucleus Accumbens; Paroxetine; Radioligand Assay; Rats; Rats, Wistar; Receptors, Dopamine D1; Selective Serotonin Reuptake Inhibitors; Sertraline | 2002 |
Differential behavioural sensitization to intermittent morphine treatment in alcohol-preferring AA and alcohol-avoiding ANA rats: role of mesolimbic dopamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alcoholism; Animals; Chromatography, High Pressure Liquid; Dopamine; Homovanillic Acid; Male; Microdialysis; Morphine; Motor Activity; Narcotics; Nucleus Accumbens; Rats; Rats, Inbred Strains | 2003 |
Implication of Rho-associated kinase in the elevation of extracellular dopamine levels and its related behaviors induced by methamphetamine in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amides; Animals; Behavior, Animal; Central Nervous System Stimulants; Dopamine; Dopamine Uptake Inhibitors; Drug Administration Routes; Enzyme Inhibitors; Extracellular Space; Homovanillic Acid; Intracellular Signaling Peptides and Proteins; Male; Methamphetamine; Microdialysis; Morphine; Narcotics; Nucleus Accumbens; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; Signal Transduction; Tetrodotoxin | 2003 |
Co-administration of dextromethorphan with morphine attenuates morphine rewarding effect and related dopamine releases at the nucleus accumbens.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analgesics, Opioid; Animals; Behavior, Animal; Chromatography, High Pressure Liquid; Conditioning, Operant; Dextromethorphan; Dopamine; Drug Synergism; Male; Microdialysis; Morphine; Motor Activity; Narcotics; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reward; Time Factors | 2003 |
Mesolimbic dopamine drives the diurnal variation in opiate-induced feeding.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Chromatography, High Pressure Liquid; Circadian Rhythm; Dopamine; Eating; Hydroxyindoleacetic Acid; Male; Morphine; Narcotics; Nucleus Accumbens; Olfactory Pathways; Rats; Rats, Sprague-Dawley; Serotonin | 2005 |
Ascorbate reduces morphine-induced extracellular DOPAC level in the nucleus accumbens: A microdialysis study in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Antioxidants; Ascorbic Acid; Chromatography, High Pressure Liquid; Drug Interactions; Electrochemistry; Extracellular Space; Male; Microdialysis; Morphine; Narcotics; Nucleus Accumbens; Rats; Rats, Wistar; Time Factors | 2005 |
A comparative study of morphine treatment regimen prior to mating and during late pregnancy.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Behavior, Animal; Body Weight; Brain Chemistry; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Homovanillic Acid; Hypothalamus; Maternal Behavior; Morphine; Motor Activity; Narcotics; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Reaction Time; Sexual Behavior, Animal; Time Factors | 2006 |
In heterozygous GDNF knockout mice the response of striatal dopaminergic system to acute morphine is altered.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analgesics, Opioid; Animals; Binding, Competitive; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Extracellular Space; Glial Cell Line-Derived Neurotrophic Factor; Homovanillic Acid; Mice; Mice, Knockout; Microdialysis; Morphine; Narcotics; Pain Measurement; Reaction Time; Statistics, Nonparametric; Time Factors; Tritium | 2006 |
Nalbuphine is effective in decreasing the rewarding effect induced by morphine in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Chromatography, High Pressure Liquid; Conditioning, Psychological; Drug Tolerance; Homovanillic Acid; Locomotion; Male; Morphine; Nalbuphine; Narcotic Antagonists; Narcotics; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Reward | 2006 |
Methamphetamine, morphine, and their combination: acute changes in striatal dopaminergic transmission evaluated by microdialysis in awake rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Dopamine; Drug Combinations; Drug Synergism; Extracellular Matrix; Methamphetamine; Microdialysis; Models, Biological; Morphine; Rats; Rats, Sprague-Dawley; Time Factors | 2006 |
Endogenous histamine inhibits the development of morphine-induced conditioned place preference.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analgesics, Opioid; Animals; Conditioning, Operant; Dopamine; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamic Acid; Histamine; Histidine; Hypothalamic Area, Lateral; Injections, Intraperitoneal; Male; Morphine; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Ventral Tegmental Area | 2007 |
18-MC acts in the medial habenula and interpeduncular nucleus to attenuate dopamine sensitization to morphine in the nucleus accumbens.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Dopamine; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Administration Schedule; Drug Interactions; Female; Homovanillic Acid; Ibogaine; Mesencephalon; Morphine; Narcotics; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Time Factors | 2007 |
Agmatine inhibits morphine-induced locomotion sensitization and morphine-induced changes in striatal dopamine and metabolites in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic alpha-Antagonists; Agmatine; Analysis of Variance; Animals; Behavior, Animal; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Dynorphins; Gene Expression Regulation; Homovanillic Acid; Idazoxan; Locomotion; Male; Morphine; Narcotics; Rats; Rats, Wistar; Time Factors | 2007 |
Dose- and time-dependent, context-induced elevation of dopamine and its metabolites in the nucleus accumbens of morphine-induced CPP rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Chromatography, High Pressure Liquid; Conditioning, Classical; Dopamine; Dose-Response Relationship, Drug; Environment; Homovanillic Acid; Male; Memory; Morphine; Narcotics; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Space Perception; Time Factors | 2009 |
Opioids in the hypothalamus control dopamine and acetylcholine levels in the nucleus accumbens.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcholine; Analgesics, Opioid; Animals; Dopamine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Methionine; Homovanillic Acid; Male; Microdialysis; Microinjections; Morphine; Naloxone; Narcotic Antagonists; Neural Pathways; Nucleus Accumbens; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley | 2010 |
Glycyl-glutamine (beta-endorphin(30-31)) inhibits morphine-induced dopamine efflux in the nucleus accumbens.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analgesics, Opioid; Animals; Dipeptides; Dopamine; Dose-Response Relationship, Drug; Male; Microdialysis; Morphine; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Reward; Time Factors | 2010 |
Enhanced tyrosine hydroxylase phosphorylation in the nucleus accumbens and nucleus tractus solitarius-A2 cell group after morphine-conditioned place preference.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Conditioning, Operant; Dopamine; Male; Methoxyhydroxyphenylglycol; Mice; Morphine; Narcotics; Neurons; Norepinephrine; Nucleus Accumbens; Phosphorylation; Solitary Nucleus; Tyrosine 3-Monooxygenase; Ventral Tegmental Area | 2010 |
Opioid-mediated regulation of A11 diencephalospinal dopamine neurons: pharmacological evidence of activation by morphine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analgesics, Opioid; Animals; Brain; Diencephalon; Dopamine; Dose-Response Relationship, Drug; Female; Male; Mice; Morphine; Neurons; Spinal Cord | 2011 |
Morphine administration modulates expression of Argonaute 2 and dopamine-related transcription factors involved in midbrain dopaminergic neurons function.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Argonaute Proteins; Body Weight; Dopamine; Drug Implants; Gene Expression Regulation; Homeodomain Proteins; Injections, Intraperitoneal; Male; Mesencephalon; Morphine; Naloxone; Nuclear Receptor Subfamily 4, Group A, Member 2; Nucleus Accumbens; Phosphorylation; Rats; Rats, Wistar; Substance-Related Disorders; Transcription Factors; Tyrosine 3-Monooxygenase; Ventral Tegmental Area | 2013 |
Ghrelin receptor antagonism of morphine-induced accumbens dopamine release and behavioral stimulation in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analgesics, Opioid; Animals; Behavior, Animal; Dopamine; Dose-Response Relationship, Drug; Ghrelin; Glycine; Homovanillic Acid; Male; Microdialysis; Morphine; Nucleus Accumbens; Rats; Rats, Wistar; Receptors, Ghrelin; Reward; Stereotyped Behavior; Triazoles | 2014 |
Dysregulation of dopaminergic regulatory mechanisms in the mesolimbic pathway induced by morphine and morphine withdrawal.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Disease Models, Animal; Dopamine; Gene Expression Regulation; Homeodomain Proteins; Imaging, Three-Dimensional; Male; Microscopy, Confocal; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Narcotics; Nuclear Receptor Subfamily 4, Group A, Member 2; Rats; Rats, Wistar; RNA, Messenger; Transcription Factors; Tyrosine 3-Monooxygenase; Ventral Tegmental Area | 2015 |
The effect of mitragynine on extracellular activity of brain dopamine and its metabolites.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Dopamine Agents; Homovanillic Acid; Methamphetamine; Mitragyna; Morphine; Narcotics; Prefrontal Cortex; Rats; Secologanin Tryptamine Alkaloids | 2022 |