3,4-dihydroxyphenylacetic acid and fenfluramine

3,4-dihydroxyphenylacetic acid has been researched along with fenfluramine in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19906 (33.33)18.7374
1990's8 (44.44)18.2507
2000's3 (16.67)29.6817
2010's1 (5.56)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Clemens, JA; Fuller, RW; Perry, KW1
Culp, S; DeSouza, EB; Lehmann, J; Zaczek, R1
Bolaños-Jimenez, F; Fattaccini, CM; Gozlan, H; Hamon, M1
Fattaccini, CM; Gozlan, H; Hamon, M1
Barthélémy, C; Bruneau, N; Jouve, J; Lelord, G; Roux, S1
Barthelemy, C; Bruneau, N; Jouve, J; Lelord, G; Martineau, J; Muh, JP1
Bettini, E; Ceci, A; Samanin, R; Spinelli, R1
Nowakowska, E; Samanin, R; Spampinato, U1
Clemens, JA; Fuller, RW; Snoddy, HD1
Curzon, G; Datla, KP; Oluyomi, AO1
Bonhomme, N; De Deurwaerdère, P; Le Moal, M; Spampinato, U1
Cook, EH; Freedman, DX; Heller, W; Leventhal, BL; Morford, M; Ravitz, AJ1
Marona-Lewicka, D; Nichols, DE; Rhee, GS; Sprague, JE1
McCann, UD; Ricaurte, GA; Yuan, J1
Fisher, H; Halladay, AK; Hesse, K; Kirschner, E; Wagner, GC1
Cremers, TI; de Boer, SF; Koolhaas, JM; Lieuwes, N; van der Vegt, BJ1
Belzung, C; Bodard, S; Chalon, S; Galineau, L; Guilloteau, D; Kodas, E1
Alves, SE; Correa, L; Gautreaux, C; Gordon, M; Hickey, GJ; Lorrain, DS; Lubbers, LS; Luine, V; Zafian, PT1

Trials

3 trial(s) available for 3,4-dihydroxyphenylacetic acid and fenfluramine

ArticleYear
Auditory evoked potential modifications according to clinical and biochemical responsiveness to fenfluramine treatment in children with autistic behavior.
    Neuropsychobiology, 1989, Volume: 21, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Autistic Disorder; Child; Child, Preschool; Dopamine; Evoked Potentials, Auditory; Female; Fenfluramine; Homovanillic Acid; Humans; Male; Phenylacetates; Randomized Controlled Trials as Topic; Reaction Time; Serotonin

1989
Urinary dopamine metabolites as indicators of the responsiveness to fenfluramine treatment in children with autistic behavior.
    Journal of autism and developmental disorders, 1989, Volume: 19, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Autistic Disorder; Child; Child, Preschool; Dopamine; Double-Blind Method; Female; Fenfluramine; Homovanillic Acid; Humans; Male; Serotonin

1989
Clinical and neurochemical effects of fenfluramine in children with autism.
    The Journal of neuropsychiatry and clinical neurosciences, 1993,Summer, Volume: 5, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adolescent; Autistic Disorder; Child; Child Behavior Disorders; Child, Preschool; Cognition; Double-Blind Method; Female; Fenfluramine; Humans; Intelligence; Male; Norepinephrine; Placebos; Plasma; Psychiatric Status Rating Scales; Serotonin; Surveys and Questionnaires

1993

Other Studies

15 other study(ies) available for 3,4-dihydroxyphenylacetic acid and fenfluramine

ArticleYear
Elevation of 3, 4-dihydroxyphenylacetic acid concentrations in rat brain and stimulation of prolactin secretion by fenfluramine: evidence for antagonism at dopamine receptor sites.
    The Journal of pharmacy and pharmacology, 1976, Volume: 28, Issue:8

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Brain Chemistry; Fenfluramine; Male; Norfenfluramine; p-Chloroamphetamine; Phenylacetates; Prolactin; Rats; Receptors, Dopamine; Stimulation, Chemical; Time Factors

1976
Regional distribution to recovery of 5-HT levels after administration of "atrophins" MDMA and D,L-fenfluramine. Stereospecificity and comparison with 5,7-dihydroxytryptamine.
    Annals of the New York Academy of Sciences, 1992, May-11, Volume: 648

    Topics: 3,4-Dihydroxyphenylacetic Acid; 3,4-Methylenedioxyamphetamine; 5,7-Dihydroxytryptamine; Animals; Atrophy; Brain; Cerebral Ventricles; Designer Drugs; Dopamine; Fenfluramine; Homovanillic Acid; Hydroxyindoleacetic Acid; Injections, Intraventricular; Male; N-Methyl-3,4-methylenedioxyamphetamine; Norepinephrine; Organ Specificity; Paroxetine; Piperidines; Rats; Rats, Inbred Strains; Serotonin; Stereoisomerism

1992
Tianeptine stimulates uptake of 5-hydroxytryptamine in vivo in the rat brain.
    Neuropharmacology, 1990, Volume: 29, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamines; Animals; Antidepressive Agents, Tricyclic; Brain; Dopamine; Fenfluramine; Hydroxyindoleacetic Acid; Male; Rats; Rats, Inbred Strains; Serotonin; Synaptosomes; Thiazepines

1990
Differential effects of d-fenfluramine and p-chloroamphetamine on H75/12-induced depletion of 5-hydroxytryptamine and dopamine in the rat brain.
    Neuropharmacology, 1991, Volume: 30, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamines; Animals; Brain; Brain Stem; Cerebral Cortex; Corpus Striatum; Dopamine; Fenfluramine; Hippocampus; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Monoamine Oxidase Inhibitors; p-Chloroamphetamine; Rats; Rats, Inbred Strains; Reference Values; Serotonin

1991
Neuroleptic-like effects of the l-isomer of fenfluramine on striatal dopamine release in freely moving rats.
    Biochemical pharmacology, 1987, Jul-15, Volume: 36, Issue:14

    Topics: 3,4-Dihydroxyphenylacetic Acid; 4-Butyrolactone; Animals; Antipsychotic Agents; Corpus Striatum; Dopamine; Drug Tolerance; Fenfluramine; Haloperidol; Homovanillic Acid; Male; Rats; Receptors, Dopamine; Secretory Rate

1987
Increased release of striatal dopamine after long-term treatment with methadone in rats: inhibition by agents which increase central 5-hydroxytryptamine transmission.
    The Journal of pharmacy and pharmacology, 1983, Volume: 35, Issue:12

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Fenfluramine; Homovanillic Acid; Male; Methadone; Piperazines; Rats; Serotonin; Synaptic Transmission

1983
Elevation by fenfluramine of 3,4-dihydroxyphenylacetic acid in brain and of corticosterone and prolactin in serum of fenfluramine-pretreated rats.
    Pharmacological research communications, 1981, Volume: 13, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Corticosterone; Fenfluramine; Male; Phenylacetates; Prolactin; Rats; Serotonin

1981
Effects of d-fenfluramine on feeding and hypothalamic 5-hydroxytryptamine and dopamine in male and female rats.
    European journal of pharmacology, 1994, Apr-01, Volume: 255, Issue:1-3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Diet; Dopamine; Feeding Behavior; Female; Fenfluramine; Food Deprivation; Hydroxyindoleacetic Acid; Hypothalamus; Male; Rats; Rats, Sprague-Dawley; Serotonin; Sex Characteristics

1994
d-fenfluramine increases striatal extracellular dopamine in vivo independently of serotonergic terminals or dopamine uptake sites.
    Journal of neurochemistry, 1995, Volume: 65, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; 5,7-Dihydroxytryptamine; Anesthesia; Animals; Citalopram; Corpus Striatum; Dialysis; Dopamine; Dose-Response Relationship, Drug; Extracellular Space; Fenfluramine; Halothane; Hydroxyindoleacetic Acid; Male; Nomifensine; Rats; Rats, Sprague-Dawley; Serotonin; Tetrodotoxin

1995
Reinforcing effects of certain serotonin-releasing amphetamine derivatives.
    Pharmacology, biochemistry, and behavior, 1996, Volume: 53, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamines; Animals; Conditioning, Operant; Dopamine; Dopamine Antagonists; Fenfluramine; Indans; Male; Microdialysis; N-Methyl-3,4-methylenedioxyamphetamine; Nucleus Accumbens; Rats; Reinforcement, Psychology; Serotonin; Serotonin Agents; Serotonin Receptor Agonists; Synaptic Transmission

1996
Neurotoxic effects of +/-fenfluramine and phenteramine, alone and in combination, on monoamine neurons in the mouse brain.
    Synapse (New York, N.Y.), 1998, Volume: 30, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Appetite Depressants; Biogenic Monoamines; Body Weight; Brain; Dopamine; Drinking Behavior; Drug Interactions; Energy Intake; Feeding Behavior; Fenfluramine; Hydroxyindoleacetic Acid; Male; Mice; Neurons; Neurotoxins; Phentermine; Serotonin

1998
Role of monoamine oxidase inhibition and monoamine depletion in fenfluramine-induced neurotoxicity and serotonin release.
    Pharmacology & toxicology, 2001, Volume: 89, Issue:5

    Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Methyltyrosine; Animals; Clorgyline; Corpus Striatum; Dopamine; Drug Interactions; Fenclonine; Fenfluramine; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Monoamine Oxidase Inhibitors; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Selegiline; Serotonin; Serotonin Antagonists; Tryptophan

2001
Cerebrospinal fluid monoamine and metabolite concentrations and aggression in rats.
    Hormones and behavior, 2003, Volume: 44, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; 5,7-Dihydroxytryptamine; Aggression; Animals; Biogenic Monoamines; Chromatography, High Pressure Liquid; Dopamine; Fenfluramine; Hydroxyindoleacetic Acid; Male; Norepinephrine; Piperazines; Pyridines; Rats; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists

2003
Prenatal 3,4-methylenedioxymethamphetamine (ecstasy) exposure induces long-term alterations in the dopaminergic and serotonergic functions in the rat.
    Brain research. Developmental brain research, 2005, Feb-08, Volume: 154, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; 3,4-Methylenedioxyamphetamine; Adrenergic Uptake Inhibitors; Age Factors; Analysis of Variance; Animals; Animals, Newborn; Autoradiography; Brain; Brain Chemistry; Dopamine; Embryo, Mammalian; Female; Fenfluramine; Hallucinogens; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Membrane Transport Proteins; Microdialysis; Nortropanes; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin; Sex Factors; Time Factors; Tyramine

2005
Estrogen receptor (ER) subtype agonists alter monoamine levels in the female rat brain.
    The Journal of steroid biochemistry and molecular biology, 2010, Volume: 122, Issue:5

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Monoamines; Cerebral Cortex; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Fenfluramine; Fluorenes; Hippocampus; Hydroxyindoleacetic Acid; Methoxyhydroxyphenylglycol; Norepinephrine; Ovariectomy; Phenols; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptors, Estrogen

2010