3,4-dihydroxyphenylacetic acid has been researched along with cocaine in 137 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (16.79) | 18.7374 |
| 1990's | 68 (49.64) | 18.2507 |
| 2000's | 39 (28.47) | 29.6817 |
| 2010's | 7 (5.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cubeddu, LX; Ferrari, GB; Hoffmann, IS | 1 |
| Algeri, S; Cattabeni, F; Di Giulio, AM; Galli, CL; Groppetti, A; Maggi, A; Ponzio, F | 1 |
| Farfel, GM; Kleven, MS; Perry, BD; Seiden, LS; Woolverton, WL | 1 |
| Carlsson, A; Hoffmann, WE; Ljung, E; Lum, JT; Piercey, MF; Svensson, K | 1 |
| Ho, IK; Hoskins, B; Hume, A; Inada, T; Polk, K; Purser, C; Rockhold, RW | 1 |
| Bissette, G; Chapman, MA; See, RE | 1 |
| Sorg, BA; Steketee, JD | 1 |
| Kuczenski, R; Segal, DS | 1 |
| De Montis, G; Devoto, P; Tagliamonte, A | 1 |
| Ho, IK; Hoskins, B; Hume, A; Inada, T; Jin, C; Polk, K; Purser, C; Rockhold, RW | 1 |
| Brown, EE; Fibiger, HC | 1 |
| Carlson, JN; Glick, SD; Keller, RW; Maisonneuve, IM | 1 |
| Atkinson, LJ; Blaha, CD; Coury, A; Phillips, AG | 1 |
| D'Aquila, PS; Gessa, GL; Hmaidan, Y; Rossetti, ZL; Serra, G | 1 |
| Guzman, NA; Hernandez, L; Hoebel, BG | 1 |
| De Souza, EB; Yeh, SY | 1 |
| Aizenstein, ML; Kuczenski, R; Segal, DS | 1 |
| Camp, DM; Robinson, TE | 1 |
| Kleven, MS; Seiden, LS | 1 |
| Kalivas, PW; Sorg, BA | 2 |
| Kalivas, PW; Murray, TF; Steketee, JD; Striplin, CD | 1 |
| Arai, Y; Kim, SK; Kinemuchi, H; Kisara, K; Oyama, K; Satoh, N; Tadano, T | 1 |
| Glick, SD; Keller, RW; Maisonneuve, IM | 1 |
| Brock, JW; Justice, JB; Ng, JP | 1 |
| Garrett, MC; Soares-da-Silva, P | 1 |
| Ho, IK; Hoskins, B; Lim, DK; Rockhold, RW; Yu, ZJ | 1 |
| Karoum, F; Suddath, RL; Wyatt, RJ | 1 |
| Duffy, P; Kalivas, PW | 3 |
| Carboni, S; Gessa, GL; Kusmin, A; Pani, L; Rossetti, ZL | 1 |
| Fibiger, HC; Martin-Iverson, MT; Szostak, C | 1 |
| Kleven, M; Schuster, C; Seiden, L; Woolverton, W | 1 |
| Gibb, J; Hanson, G; Matsuda, L | 1 |
| Kleven, MS; Seiden, LS; Woolverton, WL | 1 |
| Sivam, SP | 1 |
| Hurd, YL; Ungerstedt, U | 1 |
| Hernandez, L; Hoebel, BG | 2 |
| Akimoto, K; Hamamura, T; Otsuki, S | 1 |
| Di Chiara, G; Imperato, A | 1 |
| Fawcett, RW; Karoum, F; Wyatt, RJ | 1 |
| Funk, KF; Schmidt, J; Westermann, KH | 1 |
| Arévalo, RM; Castro, R; Palarea, MD; Rodríguez-Díaz, M | 1 |
| McQuade, PS; Richard, JW; Thakur, M | 1 |
| Bloom, FE; Ettenberg, A; Koob, GF; Pettit, HO | 1 |
| Becker, JB; Beer, ME; Castañeda, E; Robinson, TE | 1 |
| Chapin, DS; Moore, KE; Nielsen, JA | 1 |
| Barr, GA; Bridger, WH; Cooper, S; Paredes, W; Schiff, SR; Sharpless, NS | 1 |
| Clarke, DE; Miller, HH; Shore, PA | 1 |
| Burnette, B; Justice, JB; Leeb, K; Newton, P; Pocock, D; Wise, RA | 1 |
| Henderson, MG; McMillen, BA | 1 |
| Alburges, ME; Wamsley, JK | 1 |
| Carlson, JN; Glick, SD; Keller, RW; Raucci, J; Wang, S | 1 |
| Ashby, CR; Eberle, WF; Strecker, RE | 1 |
| Graham, JH; Maher, JR; Robinson, SE | 1 |
| Kimura, K; Nomikos, GG; Svensson, TH | 1 |
| Justice, JB; Parsons, LH | 1 |
| Co, C; Davies, HM; Dworkin, SI; Hemby, SE; Reboussin, D; Smith, JE | 1 |
| Balfour, DJ; Benwell, ME; Lucchi, HM | 1 |
| Brinjak, R; Chrapusta, SJ; Hitri, A; Karoum, F; Wyatt, RJ | 1 |
| Giovanni, A; Heikkila, RE; Sieber, BA; Sonsalla, PK | 1 |
| Giovanni, A; Heikkila, RE; Sonsalla, PK | 1 |
| Baker, G; McGregor, A; Roberts, DC | 2 |
| Dupont, SA; Meyer, JS | 1 |
| Buhrfiend, CM; Carvey, PM; Lin, D; Lo, ES; Silvestri, JM; Weese-Mayer, DE | 1 |
| Egan, MF; Karoum, F; Wyatt, RJ | 1 |
| Cass, WA; Flach, KA; Gerhardt, GA; Zahniser, NR | 1 |
| Fontana, DJ; Pert, A; Post, RM | 1 |
| Baptista, T; Post, RM; Weiss, SR | 1 |
| Hirobe, M; Nagao, T; Ohta, S; Ono, H; Tateyama, M | 1 |
| Hitzemann, R; McNeish, CS; Strecker, RE; Svingos, AL | 1 |
| Goeders, NE; Smith, JE | 1 |
| Ali, S; Cadet, JL; Carlson, E; Epstein, C; Hirata, H; Ladenheim, B; Moran, TH; Rothman, RB | 1 |
| Shimada, A; Yamaguchi, K; Yanagita, T | 1 |
| Ali, SF; Binienda, Z; Sandberg, JA; Slikker, W | 1 |
| Bingel, SA; Boggan, WO; Middaugh, LD; Patrick, KS; Xu, W | 1 |
| Ali, SF; Nguyen-Legros, J; Silva, MC; Silva-Araújo, A; Simon, A; Tavares, MA | 1 |
| Carlson, JN; Glick, SD; Johnson, KS; Keller, RW; Snyder-Keller, AM | 1 |
| Bunzow, JR; Chester, JA; Dziewczapolski, G; Falzone, TL; Fang, Y; Gershanik, O; Grandy, DK; Larson, JL; Low, MJ; McDougall, JA; Phillips, TJ; Pugsley, TA; Rubinstein, M; Saez, C; Zhang, G | 1 |
| Holtzman, SG; Kimmel, HL; Tallarida, RJ | 1 |
| Fibiger, HC; O'Laughlin, IA; Zernig, G | 1 |
| Changeux, JP; Fuxe, K; Léna, C; Marubio, LM; Picciotto, MR; Pich, EM; Rimondini, R; Zoli, M | 1 |
| Dickinson, SD; Gerhardt, GA; Giardina, K; Grandy, DK; Kelly, MA; Larson, GA; Low, MJ; Rubinstein, M; Sabeti, J; Zahniser, NR | 1 |
| Kirstein, CL; Philpot, RM | 1 |
| Beyer, CE; Steketee, JD | 1 |
| Chen, JP; Gardner, E; Hen, R; Scearce-Levie, K | 1 |
| Aloyo, VJ; Du, W; Harvey, JA; Pazdelski, PS | 1 |
| Donovan, DM; Kirstein, CL; Kostic, V; Miner, LL; Perry, MP; Philpot, RM; Przedborski, S; Revay, RS; Rothman, RB; Schindler, CW; Sharpe, LG; Uhl, GR | 1 |
| Demaria, JE; Fekete, MI; Freeman, ME; Lerant, AA; Levenson, CW; Nagy, GM | 1 |
| Eodice, P; Johnson, DW; Mokler, DJ; Winterbottom, H | 1 |
| Carey, R; Damianopoulos, E; DePalma, G | 1 |
| Glick, SD; Maisonneuve, IM; Szumlinski, KK | 1 |
| Beck, KD; Luine, VN; Perrotti, LI; Quiñones, V | 1 |
| Ali, SF; Beaudoin, MA; Binienda, Z; Sadovova, N; Skinner, RD; Slikker, W; Thorn, BT | 1 |
| Halladay, AK; Michna, L; Wagner, GC; Widmer, DA; Yue, Y; Zhou, R | 1 |
| Schenk, JO; Sorg, BA; Wayment, HK | 1 |
| Ayestas, M; Baumann, MH; Pepper, JP; Rothman, RB | 1 |
| Caldarone, BJ; Changeux, JP; Elsworth, JD; George, TP; Picciotto, MR; Roth, RH; Weathers-Lowin, A; Zachariou, V | 1 |
| Elsworth, JD; Morrow, BA; Roth, RH | 1 |
| Blanc, G; Cotecchia, S; Darracq, L; Drouin, C; Glowinski, J; Tassin, JP; Trovero, F | 1 |
| Ali, SF; Alper, K; Binienda, ZK; Pereira, F; Slikker, W | 1 |
| Macedo, TR; Morgadinho, MT; Oliveira, CR; Oliveira, MT; Rego, AC | 1 |
| Castro-Vale, I; de Sousa, L; Magalhães, A; Summavielle, T; Tavares, MA | 1 |
| Carey, RJ; De Souza Silva, MA; DePalma, G; Huston, JP; Müller, CP; Tomaz, C | 1 |
| Boulanger, JF; Di Paolo, T; Ekue, A; Morissette, M | 1 |
| Buckland, P; Deslandes, PN; Pache, DM; Sewell, RD | 1 |
| Cass, WA; Guseva, M; Maragos, WF; Nath, A; Pauly, JR; Turchan, JT; Young, KL | 1 |
| Black, MC; Brown, LE; Cannon, JB; Johns, JM; Lubin, DA | 1 |
| Budygin, EA; Gainetdinov, RR; Johns, JM; Lieberman, JA; Lubin, DA; Phillips, PE; Wightman, RM | 1 |
| Kehoe, P; Kosten, TA; Zhang, XY | 1 |
| Cho, AK; Kuczenski, R; Melega, WP; O'Neil, ML; Segal, DS | 1 |
| Belchior, LD; Macêdo, DS; Santos, RS; Sousa, FC; Vasconcelos, SM; Viana, GS | 1 |
| Bert, B; Carey, RJ; De Souza Silva, MA; Fink, H; Huston, JP; Müller, CP; Thönnessen, H | 1 |
| D'Astous, M; Di Paolo, T; Dluzen, DE; Gajjar, TM | 1 |
| Mayan, R; Roth-Deri, I; Yadid, G | 1 |
| Benvenga, MJ; Bymaster, FP; Calligaro, DO; Cohen, IR; Falcone, JF; Hemrick-Luecke, SK; Martin, FM; Moore, NA; Nelson, DL; Nisenbaum, LK; Rasmussen, K; Schaus, JM; Sundquist, SJ; Tupper, DE; Wiernicki, TR | 1 |
| Cunha-Oliveira, T; Macedo, T; Morgadinho, MT; Oliveira, CR; Rego, AC | 1 |
| Cho, AK; Kuczenski, R; Lacan, G; Melega, WP; O'Neil, ML; Segal, DS | 1 |
| Froimowitz, M; Gardner, EL; Giordano, A; Lepore, M; Liu, X; Paredes, W; Spector, J; Wu, KM | 1 |
| de Souza Silva, MA; Huston, JP; Jocham, G; Kart-Teke, E; Lezoch, K; Müller, CP | 1 |
| Di Monte, DA; Guillot, TS; Hatcher, JM; Jones, DP; McCormack, AL; Miller, GW; Pennell, KD; Richardson, JR | 1 |
| Belluzzi, JD; Leslie, FM; Lotfipour, S; McQuown, SC; Villégier, AS | 1 |
| de Souza Silva, MA; Huston, JP; Jocham, G; Lauber, AC; Müller, CP | 1 |
| Febo, M; Ferris, CF | 1 |
| Cadet, JL; Deng, X; Gardner, EL; Kleitz, HK; Ladenheim, B; Li, X; Peng, XQ; Stein, EA; Xi, ZX | 1 |
| Cherng, CG; Chiang, CY; Chuang, JY; Ho, MC; Kao, SF; Tsai, YP; Yu, L | 1 |
| Guerriero, RM; Kosofsky, BE; Malanga, CJ; Ren, JQ | 1 |
| Cherng, CG; Lin, KY; Lin, LC; Lu, RB; Yang, FR; Yu, L | 1 |
| Bing, G; Cao, T; Gerhardt, GA; Hinzman, JM; Lifshitz, J; Liu, M; Pauly, JR; Thomas, TC; van Bregt, DR | 1 |
| Cathala, A; Panin, F; Piazza, PV; Spampinato, U | 1 |
| Dilleen, R; Economidou, D; Everitt, BJ; Pelloux, Y; Theobald, D | 1 |
| Chiu, VM; Hill, HH; Kaplan, KA; Lukus, PA; Schenk, JO; Siems, WF; Zhang, X | 1 |
| Christiansen, SH; Gøtzsche, CR; Kiens, B; Møller, LL; Richter, EA; Serup, AK; Sylow, L; Weikop, P; Woldbye, DP | 1 |
| Baranyi, M; Gagov, H; Kalfin, R; Petkova-Kirova, P; Rakovska, A; Windisch, K | 1 |
137 other study(ies) available for 3,4-dihydroxyphenylacetic acid and cocaine
| Article | Year |
|---|---|
Metabolism and efflux of [3H]dopamine in rat neostriatum: presynaptic origin of 3,4-[3H]dihydroxyphenylacetic acid.
Topics: 2H-Benzo(a)quinolizin-2-ol, 2-Ethyl-1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-; 3,4-Dihydroxyphenylacetic Acid; Animals; Catechols; Caudate Nucleus; Cocaine; Dopamine; Drug Interactions; In Vitro Techniques; Male; Methylation; Phenylacetates; Probenecid; Putamen; Rats; Synapses | 1979 |
Significance of dopamine metabolites in the evaluation of drugs acting on dopaminergic neurons.
Topics: 3,4-Dihydroxyphenylacetic Acid; 4-Butyrolactone; Animals; Apomorphine; Cocaine; Dextroamphetamine; Dopamine; Homovanillic Acid; Male; Methyltyrosines; Neurons; Nomifensine; Pargyline; Rats; Tyramine | 1978 |
Effects of repeated injections of cocaine on catecholamine receptor binding sites, dopamine transporter binding sites and behavior in rhesus monkey.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Benzazepines; Brain; Carrier Proteins; Caudate Nucleus; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Drug Administration Schedule; Grooming; Homovanillic Acid; Hydroxyindoleacetic Acid; Iodocyanopindolol; Macaca mulatta; Male; Membrane Glycoproteins; Membrane Transport Proteins; Motor Activity; Nerve Tissue Proteins; Organ Specificity; Pindolol; Piperazines; Receptors, Adrenergic, beta; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Serotonin; Spiperone; Stereotyped Behavior; Time Factors | 1992 |
Antagonism of cocaine's pharmacological effects by the stimulant dopaminergic antagonists, (+)-AJ76 and (+)-UH232.
Topics: 3,4-Dihydroxyphenylacetic Acid; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Brain Chemistry; Cocaine; Dihydroxyphenylalanine; Dopamine; Dopamine Antagonists; Electrophysiology; Homovanillic Acid; Male; Microelectrodes; Motor Activity; Rats; Rats, Sprague-Dawley; Tetrahydronaphthalenes | 1992 |
Behavioral and neurochemical effects of continuous infusion of cocaine in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Cocaine; Corpus Striatum; Dopamine; Extracellular Space; Gas Chromatography-Mass Spectrometry; Homovanillic Acid; Infusions, Intravenous; Male; Motor Activity; Rats; Rats, Wistar; Stereotyped Behavior | 1992 |
Neurotensin increases extracellular striatal dopamine levels in vivo.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cocaine; Consciousness; Corpus Striatum; Dialysis; Dopamine; Ergolines; Extracellular Space; Female; Homovanillic Acid; Microinjections; Neurotensin; Nucleus Accumbens; Quinpirole; Rats; Rats, Sprague-Dawley | 1992 |
Mechanisms of cocaine-induced sensitization.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cocaine; Dialysis; Dopamine; Electroshock; Homovanillic Acid; Male; Microinjections; Motor Activity; Pertussis Toxin; Rats; Rats, Inbred Strains; Stress, Psychological; Virulence Factors, Bordetella | 1992 |
Differential effects of amphetamine and dopamine uptake blockers (cocaine, nomifensine) on caudate and accumbens dialysate dopamine and 3-methoxytyramine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Caudate Nucleus; Chromatography, High Pressure Liquid; Cocaine; Dopamine; Homovanillic Acid; Nomifensine; Nucleus Accumbens; Rats | 1992 |
Failure by tricyclic antidepressants to affect the increase of dopamine extracellular concentrations produced by haloperidol in the caudate and accumbens nuclei of rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Antidepressive Agents, Tricyclic; Caudate Nucleus; Cocaine; Dopamine; Drug Interactions; Haloperidol; Imipramine; Male; Nucleus Accumbens; Piperazines; Rats; Rats, Inbred Strains | 1992 |
Cocaine elevates striatal dopamine efflux in spontaneously hypertensive and Wistar-Kyoto rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Anesthesia, General; Animals; Cocaine; Consciousness; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Homovanillic Acid; Kinetics; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reference Values; Stereotaxic Techniques; Time Factors | 1992 |
Cocaine-induced conditioned locomotion: absence of associated increases in dopamine release.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Cocaine; Conditioning, Operant; Dopamine; Homovanillic Acid; Male; Motor Activity; Nucleus Accumbens; Rats | 1992 |
Within-subject sensitization of striatal dopamine release after a single injection of cocaine: an in vivo microdialysis study.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Chromatography, High Pressure Liquid; Cocaine; Corpus Striatum; Dialysis; Dopamine; Homovanillic Acid; Male; Rats; Rats, Inbred Strains | 1992 |
Cocaine-induced changes in extracellular levels of striatal dopamine measured concurrently by microdialysis with HPLC-EC and chronoamperometry.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Chromatography, High Pressure Liquid; Cocaine; Corpus Striatum; Dialysis; Dopamine; Electrochemistry; Homovanillic Acid; Male; Rats; Stereotaxic Techniques | 1992 |
Repeated treatment with imipramine potentiates cocaine-induced dopamine release and motor stimulation.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cocaine; Corpus Striatum; Dopamine; Drug Synergism; Homovanillic Acid; Imipramine; Male; Motor Activity; Rats; Rats, Inbred Strains; Stimulation, Chemical; Synaptic Transmission | 1991 |
Differential dopaminergic potency of cocaine, procaine and lidocaine infused locally in the nucleus accumbens in vivo with calibration by capillary electrophoresis in vitro.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Cocaine; Dopamine; Dopamine Agents; Electrophoresis; Homovanillic Acid; Injections; Lidocaine; Nucleus Accumbens; Procaine; Rats | 1990 |
Lack of neurochemical evidence for neurotoxic effects of repeated cocaine administration in rats on brain monoamine neurons.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Brain Mapping; Cocaine; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Neurons; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Dopamine; Receptors, Serotonin; Serotonin; Spinal Cord | 1991 |
Amphetamine, cocaine, and fencamfamine: relationship between locomotor and stereotypy response profiles and caudate and accumbens dopamine dynamics.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Caudate Nucleus; Cocaine; Dialysis; Dopamine; Dose-Response Relationship, Drug; Homovanillic Acid; Hydroxyindoleacetic Acid; Kinetics; Motor Activity; Norbornanes; Nucleus Accumbens; Rats; Stereotyped Behavior | 1991 |
The effects of four days of continuous striatal microdialysis on indices of dopamine and serotonin neurotransmission in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cocaine; Corpus Striatum; Dextroamphetamine; Dialysis; Dopamine; Female; Homovanillic Acid; Hydroxyindoleacetic Acid; Rats; Serotonin; Synaptic Transmission | 1991 |
Repeated injection of cocaine potentiates methamphetamine-induced toxicity to dopamine-containing neurons in rat striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Cocaine; Corpus Striatum; Dopamine; Drug Synergism; Homovanillic Acid; Male; Methamphetamine; Neurons; Nucleus Accumbens; Rats; Rats, Inbred Strains | 1991 |
Effects of cocaine and footshock stress on extracellular dopamine levels in the ventral striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Brain Chemistry; Cocaine; Corpus Striatum; Dialysis; Dopamine; Electroshock; Homovanillic Acid; Male; Motor Activity; Nucleus Accumbens; Olfactory Bulb; Rats; Rats, Inbred Strains; Stress, Psychological | 1991 |
Possible role for G-proteins in behavioral sensitization to cocaine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Cocaine; Dopamine; GTP-Binding Proteins; Homovanillic Acid; Kinetics; Male; Motor Activity; Neurons; Nucleus Accumbens; Pertussis Toxin; Rats; Rats, Inbred Strains; Reference Values; Virulence Factors, Bordetella | 1991 |
Inhibition of brain MAO-A and animal behaviour induced by p-hydroxyamphetamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Cerebral Ventricles; Cocaine; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Homovanillic Acid; Injections, Intraventricular; Isoenzymes; Male; Mice; Mice, Inbred Strains; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neurons; p-Hydroxyamphetamine; Prosencephalon; Reference Values; Synaptosomes | 1991 |
Similar effects of D-amphetamine and cocaine on extracellular dopamine levels in medial prefrontal cortex of rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cerebral Cortex; Chromatography, High Pressure Liquid; Cocaine; Dextroamphetamine; Dialysis; Dopamine; Female; Homovanillic Acid; Male; Neurons; Rats; Synaptic Transmission | 1990 |
Effect of chronic cocaine on dopamine synthesis in the nucleus accumbens as determined by microdialysis perfusion with NSD-1015.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cocaine; Dialysis; Dihydroxyphenylalanine; Dopamine; Hydrazines; Kinetics; Male; Nucleus Accumbens; Perfusion; Rats; Rats, Inbred Strains; Reference Values | 1990 |
Overflow of endogenous dopamine and 3,4-dihydroxyphenylacetic acid from tissues of the rat brain, elicited by electrical stimulation, depolarization by potassium and activation of carrier-mediated release.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Chromatography, High Pressure Liquid; Cocaine; Corpus Striatum; Dopamine; Electric Stimulation; In Vitro Techniques; Kinetics; Male; Neurons; Neurotransmitter Uptake Inhibitors; Piperazines; Potassium; Rats; Rats, Inbred Strains | 1990 |
Effects of acute and subacute cocaine administration on the CNS dopaminergic system in Wistar-Kyoto and spontaneously hypertensive rats: I. Levels of dopamine and metabolites.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cocaine; Corpus Striatum; Dopamine; Homovanillic Acid; Hypertension; Male; Nucleus Accumbens; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1990 |
Chronic cocaine and rat brain catecholamines: long-term reduction in hypothalamic and frontal cortex dopamine metabolism.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Catecholamines; Cerebral Cortex; Cocaine; Corpus Striatum; Dopamine; Gas Chromatography-Mass Spectrometry; Homovanillic Acid; Hypothalamus; Methoxyhydroxyphenylglycol; Norepinephrine; Nucleus Accumbens; Rats; Rats, Inbred Strains | 1990 |
Effect of acute and daily cocaine treatment on extracellular dopamine in the nucleus accumbens.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Calcium; Cocaine; Dopamine; Extracellular Space; Homovanillic Acid; Male; Nucleus Accumbens; Rats; Rats, Inbred Strains; Septal Nuclei | 1990 |
Nimodipine inhibits cocaine-induced dopamine release and motor stimulation.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Cocaine; Corpus Striatum; Dialysis; Dopamine; Homovanillic Acid; Injections, Intraperitoneal; Male; Motor Activity; Nimodipine; Rats; Rats, Inbred Strains | 1990 |
6-Hydroxydopamine lesions of the medial prefrontal cortex fail to influence intravenous self-administration of cocaine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Cerebral Cortex; Cocaine; Conditioning, Operant; Dopamine; Hydroxydopamines; Hydroxyindoleacetic Acid; Male; Nucleus Accumbens; Oxidopamine; Rats; Self Administration; Serotonin | 1986 |
Behavioral and neurochemical effects of repeated or continuous exposure to cocaine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cocaine; Conditioning, Operant; Corpus Striatum; Dopamine; Hydroxyindoleacetic Acid; Macaca mulatta; Male; Rats; Rats, Inbred Strains; Serotonin; Tyrosine 3-Monooxygenase | 1988 |
Neurochemical basis for cocaine and methamphetamine interactions.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Basal Ganglia; Cerebral Cortex; Cocaine; Corpus Striatum; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Methamphetamine; Rats; Rats, Inbred Strains; Serotonin | 1988 |
Lack of long-term monoamine depletions following repeated or continuous exposure to cocaine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Biogenic Monoamines; Brain; Brain Chemistry; Cocaine; Dopamine; Hydroxyindoleacetic Acid; Hypothalamus; Limbic System; Male; Methamphetamine; Rats; Rats, Inbred Strains; Serotonin | 1988 |
Cocaine selectively increases striatonigral dynorphin levels by a dopaminergic mechanism.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cocaine; Corpus Striatum; Dopamine; Dynorphins; Endorphins; Enkephalin, Methionine; Hydroxyindoleacetic Acid; Neuropeptides; Rats; Receptors, Dopamine; Serotonin; Substance P; Substantia Nigra | 1989 |
Cocaine: an in vivo microdialysis evaluation of its acute action on dopamine transmission in rat striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamines; Animals; Cocaine; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Homovanillic Acid; Male; Rats; Rats, Inbred Strains; Synaptic Transmission | 1989 |
Similar effects of daily cocaine and stress on mesocorticolimbic dopamine neurotransmission in the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Arousal; Cerebral Cortex; Cocaine; Corpus Striatum; Dopamine; Electroshock; Frontal Lobe; Homovanillic Acid; Limbic System; Male; Mesencephalon; Motor Activity; Norepinephrine; Nucleus Accumbens; Rats; Rats, Inbred Strains; Receptors, Dopamine; Stress, Psychological; Synaptic Transmission | 1989 |
Microdialysis studies of psychostimulants.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cocaine; Dextroamphetamine; Discrimination Learning; Dopamine; Dose-Response Relationship, Drug; Food Deprivation; Generalization, Stimulus; Homovanillic Acid; Nucleus Accumbens; Phenylpropanolamine; Rats; Septal Nuclei; Serotonin | 1989 |
Subchronic cocaine treatment enhances cocaine-induced dopamine efflux, studied by in vivo intracerebral dialysis.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cocaine; Corpus Striatum; Dopamine; Drug Tolerance; Homovanillic Acid; Male; Rats; Rats, Inbred Strains; Stereotyped Behavior | 1989 |
Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Antipsychotic Agents; Caudate Nucleus; Cocaine; Dopamine; Ethanol; Homovanillic Acid; Illicit Drugs; Kinetics; Male; Narcotics; Nicotine; Nucleus Accumbens; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Septal Nuclei; Synapses | 1988 |
Effects of daily cocaine and morphine treatment on somatodendritic and terminal field dopamine release.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Brain; Cocaine; Corpus Striatum; Dopamine; Male; Mesencephalon; Morphine; Nucleus Accumbens; Potassium; Rats; Rats, Inbred Strains | 1988 |
Food reward and cocaine increase extracellular dopamine in the nucleus accumbens as measured by microdialysis.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Cocaine; Dialysis; Dopamine; Eating; Electric Stimulation; Extracellular Space; Food; Homovanillic Acid; Hypothalamus; Kinetics; Male; Nucleus Accumbens; Rats; Rats, Inbred Strains; Reinforcement, Psychology; Reward; Septal Nuclei | 1988 |
Chronic cocaine effects on peripheral biogenic amines: a long-term reduction in peripheral dopamine and phenylethylamine production.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Amines; Cocaine; Dopamine; Drug Administration Schedule; Ganglia, Sympathetic; Male; Norepinephrine; Phenethylamines; Rats; Rats, Inbred Strains; Serotonin | 1988 |
[Biochemical characterization and differentiation of dopaminergic supersensitivity in the rat].
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Apomorphine; Cocaine; Dopamine; Haloperidol; Muscle Denervation; Rats; Receptors, Dopamine; Reserpine; Synaptosomes | 1986 |
[Role of the presynaptic receptors in the control of dopamine synthesis in the striate complex and nucleus accumbens].
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cocaine; Corpus Striatum; Dopamine; Male; Nucleus Accumbens; Rats; Rats, Inbred Strains; Receptors, Dopamine; Septal Nuclei; Substantia Nigra; Synapses | 1986 |
Some factors affecting striatal 3-methoxytyramine concentrations in the mouse and rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Cocaine; Corpus Striatum; Dopamine; Homovanillic Acid; Male; Mice; Nalidixic Acid; Naphthyridines; Nomifensine; Rats; Rats, Inbred Strains; Species Specificity | 1985 |
Destruction of dopamine in the nucleus accumbens selectively attenuates cocaine but not heroin self-administration in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cocaine; Dopamine; Heroin; Hydroxydopamines; Male; Norepinephrine; Nucleus Accumbens; Oxidopamine; Rats; Rats, Inbred Strains; Self Administration; Septal Nuclei | 1984 |
A simple in vitro technique to measure the release of endogenous dopamine and dihydroxyphenylacetic acid from striatal tissue using high performance liquid chromatography with electrochemical detection.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Chromatography, High Pressure Liquid; Cocaine; Corpus Striatum; Dopamine; Electrochemistry; Male; Phenylacetates; Potassium; Rats; Temperature | 1984 |
Differential effects of d-amphetamine, beta-phenylethylamine, cocaine and methylphenidate on the rate of dopamine synthesis in terminals of nigrostriatal and mesolimbic neurons and on the efflux of dopamine metabolites into cerebroventricular perfusates o
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Central Nervous System Agents; Cerebral Ventricles; Cocaine; Corpus Striatum; Dextroamphetamine; Dopamine; Dose-Response Relationship, Drug; Male; Methylphenidate; Neurons; Nucleus Accumbens; Olfactory Bulb; Phenethylamines; Rats; Rats, Inbred Strains | 1983 |
Classical conditioning, decay and extinction of cocaine-induced hyperactivity and stereotypy.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Brain Chemistry; Cocaine; Conditioning, Classical; Dopamine; Extinction, Psychological; Homovanillic Acid; Humans; Hyperkinesis; Male; Rats; Rats, Inbred Strains; Stereotyped Behavior; Time Factors | 1983 |
In vivo monoamine oxidase inhibition by d-amphetamine.
Topics: 2H-Benzo(a)quinolizin-2-ol, 2-Ethyl-1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-; 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Brain; Cocaine; Corpus Striatum; Dextroamphetamine; Haloperidol; Male; Monoamine Oxidase Inhibitors; Phenelzine; Rats | 1980 |
Fluctuations in nucleus accumbens dopamine concentration during intravenous cocaine self-administration in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cocaine; Dopamine; Dose-Response Relationship, Drug; Injections, Intravenous; Male; Microdialysis; Nucleus Accumbens; Rats; Rats, Inbred Strains; Self Administration; Time Factors | 1995 |
Changes in dopamine, serotonin and their metabolites in discrete brain areas of rat offspring after in utero exposure to cocaine or related drugs.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Amitriptyline; Amygdala; Analysis of Variance; Animals; Brain; Catalepsy; Cocaine; Corpus Striatum; Dopamine; Female; Haloperidol; Hippocampus; Hydroxyindoleacetic Acid; Hypothalamus; Male; Nalidixic Acid; Naphthyridines; Organ Specificity; Prefrontal Cortex; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Reference Values; Serotonin | 1993 |
Effects on monoamine levels in rat CNS after chronic administration of cocaine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Cerebral Cortex; Chromatography, High Pressure Liquid; Cocaine; Corpus Striatum; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Norepinephrine; Rats; Receptors, Dopamine; Serotonin; Up-Regulation | 1993 |
Neurochemical predisposition to self-administer cocaine in rats: individual differences in dopamine and its metabolites.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Chromatography, High Pressure Liquid; Cocaine; Dopamine; Female; Homovanillic Acid; Hydroxyindoleacetic Acid; Microdialysis; Rats; Rats, Sprague-Dawley; Self Administration; Tissue Distribution | 1994 |
Extracellular dopamine and its metabolites in the nucleus accumbens of Fischer and Lewis rats: basal levels and cocaine-induced changes.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Cocaine; Dopamine; Extracellular Space; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Morphine; Nucleus Accumbens; Rats; Rats, Inbred F344; Rats, Inbred Lew | 1995 |
The effect of cocaine and other local anesthetics on central dopaminergic neurotransmission.
Topics: 3,4-Dihydroxyphenylacetic Acid; Anesthetics, Local; Animals; Cocaine; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Frontal Lobe; Male; Monoamine Oxidase Inhibitors; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Synaptic Transmission | 1995 |
Effects of amperozide on psychostimulant-induced hyperlocomotion and dopamine release in the nucleus accumbens.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylglucosamine; Amphetamine; Animals; Cocaine; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Motor Activity; Nucleus Accumbens; Piperazines; Psychotropic Drugs; Rats; Rats, Wistar | 1993 |
Effects of cocaine and footshock stress on extracellular dopamine levels in the medial prefrontal cortex.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cocaine; Dialysis; Dopamine; Electroshock; Extracellular Space; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Motor Activity; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Stress, Psychological | 1993 |
Serotonin and dopamine sensitization in the nucleus accumbens, ventral tegmental area, and dorsal raphe nucleus following repeated cocaine administration.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Cocaine; Dopamine; Hydroxyindoleacetic Acid; Kinetics; Male; Microdialysis; Nucleus Accumbens; Organ Specificity; Raphe Nuclei; Rats; Rats, Wistar; Serotonin; Ventral Tegmental Area | 1993 |
Comparison of a novel tropane analog of cocaine, 2 beta-propanoyl-3 beta-(4-tolyl) tropane with cocaine HCl in rats: nucleus accumbens extracellular dopamine concentration and motor activity.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cocaine; Dopamine; Dose-Response Relationship, Drug; Homovanillic Acid; Male; Motor Activity; Nucleus Accumbens; Rats; Rats, Inbred F344 | 1995 |
Influence of tetrodotoxin and calcium on changes in extracellular dopamine levels evoked by systemic nicotine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Calcium; Chromatography, High Pressure Liquid; Cocaine; Dextroamphetamine; Dopamine; Extracellular Space; Homovanillic Acid; Male; Nicotine; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Tetrodotoxin | 1993 |
Regional effects of amphetamine, cocaine, nomifensine and GBR 12909 on the dynamics of dopamine release and metabolism in the rat brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Methyltyrosine; Animals; Behavior, Animal; Brain Chemistry; Central Nervous System Stimulants; Cocaine; Dextroamphetamine; Dopamine; Dopamine Uptake Inhibitors; Male; Methyltyrosines; Nomifensine; Piperazines; Rats; Rats, Sprague-Dawley; Tyrosine 3-Monooxygenase | 1994 |
Studies on species sensitivity to the dopaminergic neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Part 1: Systemic administration.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Animals; Cocaine; Dopamine; Guanethidine; Male; Mice; Microdialysis; Monoamine Oxidase; MPTP Poisoning; Neostriatum; Neurons; Premedication; Rats; Rats, Sprague-Dawley; Species Specificity; Synaptosomes | 1994 |
Studies on species sensitivity to the dopaminergic neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Part 2: Central administration of 1-methyl-4-phenylpyridinium.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Animals; Cocaine; Dopamine; Dose-Response Relationship, Drug; Guanethidine; Male; Mice; Monoamine Oxidase; MPTP Poisoning; Neostriatum; Premedication; Rats; Rats, Sprague-Dawley; Species Specificity | 1994 |
Effect of 6-hydroxydopamine lesions of the amygdala on intravenous cocaine self-administration under a progressive ratio schedule of reinforcement.
Topics: 3,4-Dihydroxyphenylacetic Acid; 5,7-Dihydroxytryptamine; Amygdala; Analysis of Variance; Animals; Behavior, Animal; Benzazepines; Brain; Chlordiazepoxide; Cocaine; Desipramine; Dopamine; Estrus; Female; Fluoxetine; Ibotenic Acid; Injections, Intravenous; Male; Organ Specificity; Oxidopamine; Rats; Rats, Wistar; Self Administration; Time Factors; Tryptophan | 1994 |
Prenatal cocaine administration stimulates fetal brain tyrosine hydroxylase activity.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Cocaine; Dopamine; Embryonic and Fetal Development; Female; Maternal-Fetal Exchange; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Tyrosine 3-Monooxygenase | 1993 |
Effect of cocaine in early gestation on striatal dopamine and neurotrophic activity.
Topics: 3,4-Dihydroxyphenylacetic Acid; Abnormalities, Drug-Induced; Animals; Apoptosis; Cells, Cultured; Cerebellum; Cocaine; Corpus Striatum; Dopamine; Female; Pregnancy; Rabbits | 1993 |
Selective reduction in dopamine turnover in the rat frontal cortex and hypothalamus during withdrawal from repeated cocaine exposure.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cocaine; Dopamine; Hypothalamus; Male; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome | 1994 |
Clearance of exogenous dopamine in rat dorsal striatum and nucleus accumbens: role of metabolism and effects of locally applied uptake inhibitors.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Catechol O-Methyltransferase; Cocaine; Corpus Striatum; Deoxyepinephrine; Dopamine; Electrochemistry; Kinetics; Male; Microinjections; Nomifensine; Nucleus Accumbens; Oxidopamine; Prosencephalon; Rats; Rats, Sprague-Dawley; Time Factors | 1993 |
Conditioned increases in mesolimbic dopamine overflow by stimuli associated with cocaine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cocaine; Dizocilpine Maleate; Dopamine; Homovanillic Acid; Male; Microdialysis; Motor Activity; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Stereotyped Behavior; Time Factors | 1993 |
Carbamazepine attenuates cocaine-induced increases in dopamine in the nucleus accumbens: an in vivo dialysis study.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Carbamazepine; Cocaine; Dialysis; Dopamine; Homovanillic Acid; Injections, Intravenous; Male; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Weight Gain | 1993 |
Inhibitory effect of 4-phenyltetrahydroisoquinoline on locomotion and dopamine release induced by micro-injection of methamphetamine into the nucleus accumbens of the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Cocaine; Dialysis; Dopamine; Homovanillic Acid; Isoquinolines; Male; Methamphetamine; Microinjections; Motor Activity; Nucleus Accumbens; Rats; Rats, Wistar; Tetrahydroisoquinolines | 1993 |
The 5-HT3 antagonist zacopride attenuates cocaine-induced increases in extracellular dopamine in rat nucleus accumbens.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chromatography, High Pressure Liquid; Cocaine; Dialysis; Dopamine; Extracellular Space; Homovanillic Acid; Male; Motor Activity; Nucleus Accumbens; Prosencephalon; Rats; Rats, Sprague-Dawley; Serotonin Antagonists | 1993 |
Intracranial cocaine self-administration into the medial prefrontal cortex increases dopamine turnover in the nucleus accumbens.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cocaine; Dopamine; Male; Nucleus Accumbens; Prefrontal Cortex; Rats; Rats, Inbred F344; Self Administration; Tyrosine | 1993 |
Superoxide radicals mediate the biochemical effects of methylenedioxymethamphetamine (MDMA): evidence from using CuZn-superoxide dismutase transgenic mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Autoradiography; Cocaine; Corpus Striatum; Dopamine; Female; Humans; Male; Mice; Mice, Transgenic; N-Methyl-3,4-methylenedioxyamphetamine; Receptors, Dopamine; Superoxide Dismutase; Superoxides; Tissue Distribution | 1995 |
Effect of 6-hydroxydopamine lesions of the medial prefrontal cortex on intravenous cocaine self-administration under a progressive ratio schedule of reinforcement.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Adrenergic Uptake Inhibitors; Animals; Blood Pressure; Chromatography, High Pressure Liquid; Cocaine; Conditioning, Operant; Desipramine; Dopamine; Dopamine Uptake Inhibitors; Injections, Intravenous; Male; Oxidopamine; Prefrontal Cortex; Rats; Rats, Wistar; Reinforcement Schedule; Self Administration | 1996 |
Neurochemical analysis of the psychotoxicity of methamphetamine and cocaine by microdialysis in the rat brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cocaine; Cognition Disorders; Corpus Striatum; Dopamine; Hydroxyindoleacetic Acid; Male; Methamphetamine; Microdialysis; Motor Activity; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Serotonin | 1996 |
Alterations in electroencephalographic signals and monoamine concentrations in the rat brain following cocaine and methamphetamine treatment.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Cocaine; Dopamine; Electroencephalography; Homovanillic Acid; Methamphetamine; Rats; Rats, Sprague-Dawley; Serotonin | 1996 |
A murine model of prenatal cocaine exposure: effects on the mother and the fetus.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animal Nutritional Physiological Phenomena; Animals; Behavior, Animal; Body Weight; Cocaine; Dopamine; Dose-Response Relationship, Drug; Eating; Embryonic and Fetal Development; Female; Fetus; Injections, Subcutaneous; Intubation, Gastrointestinal; Mice; Mice, Inbred C57BL; Motor Activity; Narcotics; Pregnancy | 1996 |
The effects of prenatal exposure to cocaine on the dopaminergic cells in the rat retina. An immunocytochemical and neurochemical study.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Female; Homovanillic Acid; Immunohistochemistry; Male; Neurons; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Retina; Tyrosine 3-Monooxygenase | 1996 |
Effects of prenatal cocaine exposure on the mesocorticolimbic dopamine system: an in vivo microdialysis study in the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cocaine; Dopamine; Female; Limbic System; Maternal Exposure; Microdialysis; Nucleus Accumbens; Rats | 1996 |
Mice lacking dopamine D4 receptors are supersensitive to ethanol, cocaine, and methamphetamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amino Acid Sequence; Animals; Antipsychotic Agents; Behavior, Animal; Central Nervous System Depressants; Clozapine; Cocaine; Corpus Striatum; Dopamine; Dopamine Agents; Ethanol; Genotype; Humans; Levodopa; Locomotion; Maternal Behavior; Methamphetamine; Mice; Mice, Knockout; Molecular Sequence Data; Motor Activity; Mutagenesis, Site-Directed; Narcotics; Nucleus Accumbens; Receptors, Dopamine D2; Receptors, Dopamine D4; Sensitivity and Specificity; Substantia Nigra; Transcription, Genetic | 1997 |
Synergism between buprenorphine and cocaine on the rotational behavior of the nigrally-lesioned rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Buprenorphine; Catecholamines; Cocaine; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Male; Narcotic Antagonists; Narcotics; Rats; Rats, Sprague-Dawley; Rotation; Stereotyped Behavior; Substantia Nigra | 1997 |
Nicotine and heroin augment cocaine-induced dopamine overflow in nucleus accumbens.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cocaine; Dopamine; Heroin; Homovanillic Acid; Male; Microdialysis; Narcotics; Nicotine; Nicotinic Agonists; Nucleus Accumbens; Rats; Rats, Wistar | 1997 |
Acetylcholine receptors containing the beta2 subunit are involved in the reinforcing properties of nicotine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcholine; Animals; Binding Sites; Carrier Proteins; Cocaine; Conditioning, Operant; Dopamine; Dopamine Plasma Membrane Transport Proteins; Homovanillic Acid; In Vitro Techniques; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Knockout; Microdialysis; Motor Activity; Nerve Tissue Proteins; Nicotine; Nucleus Accumbens; Patch-Clamp Techniques; Receptors, Nicotinic; Second Messenger Systems; Substantia Nigra; Ventral Tegmental Area | 1998 |
Dopamine D2 receptor-deficient mice exhibit decreased dopamine transporter function but no changes in dopamine release in dorsal striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Autoreceptors; Brain Chemistry; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Extracellular Space; Female; Homovanillic Acid; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Knockout; Microdialysis; Nerve Tissue Proteins; Raclopride; Radioligand Assay; Receptors, Dopamine D2; Salicylamides; Tritium | 1999 |
Repeated cocaine exposure: effects on catecholamines in the nucleus accumbens septi of periadolescent animals.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Catecholamines; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Female; Homovanillic Acid; Male; Microdialysis; Norepinephrine; Nucleus Accumbens; Rats; Rats, Sprague-Dawley | 1999 |
Dopamine depletion in the medial prefrontal cortex induces sensitized-like behavioral and neurochemical responses to cocaine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Brain Chemistry; Chromatography, High Pressure Liquid; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Tolerance; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Microdialysis; Nucleus Accumbens; Oxidopamine; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Sympatholytics; Synaptic Transmission | 1999 |
5-HT receptor knockout mice: pharmacological tools or models of psychiatric disorders.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aggression; Animals; Behavior, Animal; Cocaine; Disease Models, Animal; Dopamine; Dopamine Antagonists; Feeding Behavior; gamma-Aminobutyric Acid; Indoles; Mental Disorders; Mice; Mice, Knockout; N-Methyl-3,4-methylenedioxyamphetamine; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Substance-Related Disorders | 1999 |
Effects of prenatal cocaine exposure on amphetamine-induced dopamine release in the caudate nucleus of the adult rabbit.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Caudate Nucleus; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Female; Homovanillic Acid; Microdialysis; Pregnancy; Prenatal Exposure Delayed Effects; Presynaptic Terminals; Rabbits; Radioligand Assay | 1999 |
Cocaine reward and MPTP toxicity: alteration by regional variant dopamine transporter overexpression.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Carrier Proteins; Chromatography, High Pressure Liquid; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Female; Gene Expression Regulation; Genetic Variation; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Inbred Strains; Mice, Transgenic; Motor Activity; MPTP Poisoning; Nerve Tissue Proteins; Promoter Regions, Genetic; Rats; Recombinant Fusion Proteins; Reward; Serotonin; Substantia Nigra; Transgenes; Tyrosine 3-Monooxygenase | 1999 |
Dopamine transporters participate in the physiological regulation of prolactin.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Carrier Proteins; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Estradiol; Female; Hypothalamo-Hypophyseal System; Immunohistochemistry; Mazindol; Median Eminence; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Neurosecretory Systems; Prolactin; Rats; Rats, Sprague-Dawley; Tyrosine 3-Monooxygenase | 2000 |
Decreased accumbens dopamine release after cocaine challenge in behaviorally sensitized female rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Female; Microdialysis; Motor Activity; Nucleus Accumbens; Piperazines; Rats; Rats, Sprague-Dawley; Time Factors | 2000 |
The 5-HT(1A) antagonist WAY 100635 can block the low-dose locomotor stimulant effects of cocaine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Brain Chemistry; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Limbic System; Locomotion; Male; Piperazines; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists | 2000 |
Differential effects of ibogaine on behavioural and dopamine sensitization to cocaine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Catecholamines; Cocaine; Dopamine; Female; Homovanillic Acid; Ibogaine; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Stereotyped Behavior | 2000 |
Progesterone and cocaine administration affect serotonin in the medial prefrontal cortex of ovariectomized rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cocaine; Dopamine; Estrogens; Female; Homovanillic Acid; Hydroxyindoleacetic Acid; Injections, Intraperitoneal; Injections, Subcutaneous; Norepinephrine; Ovariectomy; Prefrontal Cortex; Progesterone; Rats; Rats, Inbred F344; Serotonin | 2000 |
Application of electrophysiological method to study interactions between ibogaine and cocaine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Brain Chemistry; Cerebral Cortex; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Drug Interactions; Electroencephalography; Excitatory Amino Acid Antagonists; Homovanillic Acid; Hydroxyindoleacetic Acid; Ibogaine; Male; Rats; Rats, Sprague-Dawley; Serotonin; Time Factors; Wakefulness | 2000 |
Regulation of EphB1 expression by dopamine signaling.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Animals, Newborn; Cerebral Cortex; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Dopamine; Dopamine Uptake Inhibitors; Ephrin-B1; Female; Gene Expression; Homovanillic Acid; In Situ Hybridization; Membrane Proteins; Mice; Mice, Inbred Strains; Nerve Degeneration; Oxidopamine; Pregnancy; RNA, Messenger; Signal Transduction; Substantia Nigra; Sympatholytics | 2000 |
Characterization of extracellular dopamine clearance in the medial prefrontal cortex: role of monoamine uptake and monoamine oxidase inhibition.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Monoamines; Carrier Proteins; Chromatography, High Pressure Liquid; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Electrochemistry; Electrodes, Implanted; Extracellular Space; Homovanillic Acid; Male; Membrane Glycoproteins; Membrane Transport Proteins; Microdialysis; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Nerve Tissue Proteins; Norepinephrine Plasma Membrane Transport Proteins; Pargyline; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Sodium; Symporters | 2001 |
Inhibition of MAO-A fails to alter cocaine-induced increases in extracellular dopamine and norepinephrine in rat nucleus accumbens.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Clorgyline; Cocaine; Cocaine-Related Disorders; Dopamine; Dopamine Uptake Inhibitors; Extracellular Space; Hydroxyindoleacetic Acid; Male; Microdialysis; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Norepinephrine; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Serotonin | 2001 |
Nicotine receptor inactivation decreases sensitivity to cocaine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcholine; Animals; Cholinergic Fibers; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Dopamine; Dose-Response Relationship, Drug; Female; Male; Mice; Mice, Knockout; Neurons; Nicotine; Nucleus Accumbens; Receptors, Nicotinic | 2001 |
Prenatal cocaine exposure increases mesoprefrontal dopamine neuron responsivity to mild stress.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Cocaine; Cocaine-Related Disorders; Dopamine; Electric Stimulation; Female; Gyrus Cinguli; Neural Pathways; Neurons; Prefrontal Cortex; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Stress, Physiological; Ventral Tegmental Area | 2001 |
Alpha1b-adrenergic receptors control locomotor and rewarding effects of psychostimulants and opiates.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic alpha-Antagonists; Animals; Brain; Central Nervous System Stimulants; Choice Behavior; Cocaine; Crosses, Genetic; Dextroamphetamine; Dopamine; Dopamine Agonists; Male; Mice; Mice, Inbred Strains; Mice, Knockout; Morphine; Motor Activity; Muscarinic Antagonists; Narcotics; Norepinephrine; Prazosin; Receptors, Adrenergic, alpha-1; Receptors, Dopamine D1; Receptors, Dopamine D2; Reward; Substance-Related Disorders; Synaptic Transmission | 2002 |
Adaptation to repeated cocaine administration in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Caudate Nucleus; Cocaine; Cocaine-Related Disorders; Cortical Synchronization; Disease Models, Animal; Dopamine; Drug Administration Schedule; Electroencephalography; Frontal Lobe; Homovanillic Acid; Humans; Male; Rats; Rats, Sprague-Dawley | 2002 |
Toxic effects of opioid and stimulant drugs on undifferentiated PC12 cells.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cell Survival; Chromatin; Cocaine; Dextroamphetamine; Dopamine; Heroin; L-Lactate Dehydrogenase; Models, Animal; Morphine; Narcotics; PC12 Cells; Pheochromocytoma; Rats; Reactive Oxygen Species | 2002 |
Neonatal exposure to cocaine: altered dopamine levels in the amygdala and behavioral outcomes in the developing rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Amygdala; Animals; Animals, Newborn; Cocaine; Dopamine; Female; Male; Motor Activity; Rats; Rats, Wistar | 2002 |
The selective serotonin(1A)-receptor antagonist WAY 100635 blocks behavioral stimulating effects of cocaine but not ventral striatal dopamine increase.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Extracellular Space; Grooming; Male; Microdialysis; Motor Activity; Neostriatum; Piperazines; Pyridines; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists | 2002 |
Lack of effect of testosterone and dihydrotestosterone compared to 17beta-oestradiol in 1-methyl-4-phenyl-1,2,3,6, tetrahydropyridine-mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Autoradiography; Cocaine; Dihydrotestosterone; Dopamine; Dopamine Plasma Membrane Transport Proteins; Estradiol; Gonadal Steroid Hormones; Homovanillic Acid; In Situ Hybridization; Iodine Radioisotopes; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; MPTP Poisoning; Nerve Tissue Proteins; Neuropeptides; RNA, Messenger; Testosterone; Tetrabenazine; Tritium; Vesicular Biogenic Amine Transport Proteins; Vesicular Monoamine Transport Proteins | 2002 |
Morphine, cocaine and antidepressant induced motivational activity and midbrain dopaminergic neurotransmission.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Central Nervous System Stimulants; Chromatography, High Pressure Liquid; Cocaine; Conditioning, Psychological; Corpus Striatum; Dopamine; Homovanillic Acid; Male; Mesencephalon; Morphine; Motivation; Nucleus Accumbens; Paroxetine; Radioligand Assay; Rats; Rats, Wistar; Receptors, Dopamine D1; Selective Serotonin Reuptake Inhibitors; Sertraline | 2002 |
Human immunodeficiency virus-1 Tat protein and methamphetamine interact synergistically to impair striatal dopaminergic function.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antioxidants; Binding, Competitive; Body Temperature; Cell Death; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Drug Synergism; Gene Products, tat; HIV-1; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Intracellular Membranes; Male; Membrane Glycoproteins; Membrane Potentials; Membrane Transport Proteins; Methamphetamine; Mitochondria; Nerve Tissue Proteins; Neurons; Rats; Rats, Sprague-Dawley; Serotonin; tat Gene Products, Human Immunodeficiency Virus | 2002 |
Effects of chronic cocaine on monoamine levels in discrete brain structures of lactating rat dams.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aggression; Animals; Behavior, Animal; Biogenic Monoamines; Brain Chemistry; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Female; Homovanillic Acid; Hydroxyindoleacetic Acid; Lactation; Oxytocin; Pregnancy; Rats; Rats, Sprague-Dawley; Serotonin | 2003 |
Presynaptic dopaminergic function is largely unaltered in mesolimbic and mesostriatal terminals of adult rats that were prenatally exposed to cocaine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Autoreceptors; Cocaine; Corpus Striatum; Dopamine; Dopamine Agonists; Dopamine Uptake Inhibitors; Electric Stimulation; Female; Homovanillic Acid; In Vitro Techniques; Limbic System; Male; Pregnancy; Prenatal Exposure Delayed Effects; Presynaptic Terminals; Quinpirole; Rats; Rats, Sprague-Dawley | 2003 |
Chronic neonatal isolation stress enhances cocaine-induced increases in ventral striatal dopamine levels in rat pups.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Animals, Newborn; Chronic Disease; Cocaine; Cocaine-Related Disorders; Dopamine; Dose-Response Relationship, Drug; Female; Male; Microdialysis; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Sex Characteristics; Social Isolation; Stress, Physiological; Up-Regulation | 2003 |
Escalating dose methamphetamine pretreatment alters the behavioral and neurochemical profiles associated with exposure to a high-dose methamphetamine binge.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Binding Sites; Body Temperature; Brain Chemistry; Central Nervous System Stimulants; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Administration Schedule; Homovanillic Acid; Male; Methamphetamine; Motor Activity; Neostriatum; Rats; Rats, Sprague-Dawley; Stereotyped Behavior; Tetrabenazine; Time Factors; Tritium | 2003 |
Alterations in monoamine levels after cocaine-induced status epilepticus and death in striatum and prefrontal cortex of mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Biogenic Monoamines; Brain Chemistry; Cell Count; Cell Death; Chromatography, High Pressure Liquid; Cocaine; Corpus Striatum; Electrochemistry; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Mice; Prefrontal Cortex; Status Epilepticus | 2004 |
Nucleus accumbens serotonin1A receptors control cocaine-induced hyperactivity but not local serotonin increase: an in vivo microdialysis study.
Topics: 3,4-Dihydroxyphenylacetic Acid; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Cocaine; Hydroxyindoleacetic Acid; Hyperkinesis; Male; Microdialysis; Nucleus Accumbens; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Serotonin; Serotonin Receptor Agonists | 2004 |
Dopamine transporter as a marker of neuroprotection in methamphetamine-lesioned mice treated acutely with estradiol.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Autoradiography; Chromatography, High Pressure Liquid; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Drug Interactions; Estradiol; Female; In Situ Hybridization; Iodine Isotopes; Membrane Glycoproteins; Membrane Transport Proteins; Methamphetamine; Mice; Neostriatum; Nerve Tissue Proteins; Nervous System Diseases; Neuroprotective Agents; Ovariectomy; Protein Binding; RNA, Messenger; Substantia Nigra; Time Factors | 2004 |
A hypothalamic endorphinic lesion attenuates acquisition of cocaine self-administration in the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Arcuate Nucleus of Hypothalamus; Behavior, Animal; beta-Endorphin; Brain Chemistry; Cocaine; Corticosterone; Dopamine; Dopamine Uptake Inhibitors; Drug Interactions; Estradiol; Estrogens; Female; Neurons; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Self Administration; Time Factors | 2006 |
Preclinical pharmacology of FMPD [6-fluoro-10-[3-(2-methoxyethyl)-4-methyl-piperazin-1-yl]-2-methyl-4H-3-thia-4,9-diaza-benzo[f]azulene]: a potential novel antipsychotic with lower histamine H1 receptor affinity than olanzapine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antipsychotic Agents; Benzodiazepines; Body Weight; Catalepsy; Cocaine; Corticosterone; Drug Evaluation, Preclinical; Electrochemistry; Electrophysiology; Fasting; Female; Immunohistochemistry; Male; Molecular Structure; Motor Activity; Nucleus Accumbens; Olanzapine; Piperazines; Prolactin; Quipazine; Radioligand Assay; Rats; Rats, Inbred F344; Rats, Inbred Strains; Rats, Sprague-Dawley; Receptors, Histamine H1; Serotonin Receptor Agonists; Thiophenes; Time Factors | 2005 |
Differential cytotoxic responses of PC12 cells chronically exposed to psychostimulants or to hydrogen peroxide.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adenosine Triphosphate; Amphetamine; Animals; Cell Survival; Central Nervous System Stimulants; Cocaine; Cytosol; Dopamine; Hydrogen Peroxide; PC12 Cells; Rats; Time Factors | 2006 |
Escalating dose pretreatment induces pharmacodynamic and not pharmacokinetic tolerance to a subsequent high-dose methamphetamine binge.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Amphetamine-Related Disorders; Animals; Body Temperature; Central Nervous System Stimulants; Chromatography, High Pressure Liquid; Cocaine; Dopamine Uptake Inhibitors; Gas Chromatography-Mass Spectrometry; Homovanillic Acid; Male; Methamphetamine; Microdialysis; Neostriatum; Rats; Rats, Sprague-Dawley | 2006 |
A slow-onset, long-duration indanamine monoamine reuptake inhibitor as a potential maintenance pharmacotherapy for psychostimulant abuse: effects in laboratory rat models relating to addiction.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Behavior, Animal; Cocaine; Dialysis; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Homovanillic Acid; Hydroxyindoleacetic Acid; Indans; Indenes; Male; Neurotransmitter Uptake Inhibitors; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Self Administration; Substance-Related Disorders; Time Factors | 2006 |
Neurokinin receptor antagonism attenuates cocaine's behavioural activating effects yet potentiates its dopamine-enhancing action in the nucleus accumbens core.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Antipsychotic Agents; Behavior, Animal; Cocaine; Conditioning, Operant; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Extracellular Fluid; Homovanillic Acid; Locomotion; Male; Microdialysis; Nucleus Accumbens; Piperidines; Rats; Rats, Wistar; Receptors, Neurokinin-3 | 2006 |
Dieldrin exposure induces oxidative damage in the mouse nigrostriatal dopamine system.
Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Synuclein; Analysis of Variance; Animals; Chromatography, High Pressure Liquid; Cocaine; Corpus Striatum; Dieldrin; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Gene Expression Regulation; Glutathione; Homovanillic Acid; Male; Mice; Mice, Inbred C57BL; Organ Culture Techniques; Oxidative Stress; Protein Carbonylation; Substantia Nigra | 2007 |
Tranylcypromine enhancement of nicotine self-administration.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Benzazepines; Chromatography, High Pressure Liquid; Cocaine; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Electrochemistry; Half-Life; Male; Microdialysis; Monoamine Oxidase Inhibitors; Nicotine; Nicotinic Agonists; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Reward; Self Administration; Tranylcypromine | 2007 |
Neurokinin 3 receptor activation potentiates the psychomotor and nucleus accumbens dopamine response to cocaine, but not its place conditioning effects.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Cocaine; Conditioning, Psychological; Dopamine; Dopamine Uptake Inhibitors; Locomotion; Male; Microdialysis; Motor Activity; Nucleus Accumbens; Peptide Fragments; Random Allocation; Rats; Rats, Wistar; Receptors, Neurokinin-3; Substance P | 2007 |
Development of cocaine sensitization before pregnancy affects subsequent maternal retrieval of pups and prefrontal cortical activity during nursing.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Animals, Newborn; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Dopamine; Dopamine Uptake Inhibitors; Female; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Maternal Behavior; Oxygen; Prefrontal Cortex; Pregnancy; Rats; Reaction Time; Time Factors | 2007 |
A single high dose of methamphetamine increases cocaine self-administration by depletion of striatal dopamine in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Central Nervous System Stimulants; Cocaine; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Drug Synergism; Extracellular Space; Fever; Male; Methamphetamine; Motor Activity; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Self Administration | 2009 |
Chronic treatment with monoamine oxidase-B inhibitors decreases cocaine reward in mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Behavior, Animal; Cocaine; Conditioning, Operant; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Administration Schedule; Feeding Behavior; Hydroxyindoleacetic Acid; Male; Mice; Mice, Inbred C57BL; Monoamine Oxidase Inhibitors; Motor Activity; Reinforcement Schedule; Reward; Serotonin; Time Factors | 2009 |
Augmentation of cocaine-sensitized dopamine release in the nucleus accumbens of adult mice following prenatal cocaine exposure.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Female; Hydroxyindoleacetic Acid; Mice; Microdialysis; Motor Activity; Nucleus Accumbens; Pregnancy; Prenatal Exposure Delayed Effects; Serotonin | 2009 |
Memantine abolishes the formation of cocaine-induced conditioned place preference possibly via its IL-6-modulating effect in medial prefrontal cortex.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Anesthetics, Local; Animals; Cocaine; Conditioning, Operant; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Immunosuppressive Agents; Interleukin-1beta; Interleukin-6; Male; Memantine; Mice; Mice, Inbred C57BL; Motor Activity; Nucleus Accumbens; Prefrontal Cortex; Thalidomide; Tumor Necrosis Factor-alpha | 2011 |
Substantia nigra vulnerability after a single moderate diffuse brain injury in the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Atrophy; Brain Injuries; Calcium-Binding Proteins; Carrier Proteins; Cell Count; Chromatography, High Pressure Liquid; Cocaine; Disease Models, Animal; Dopamine; Electrochemical Techniques; Gene Expression Regulation; Homovanillic Acid; Isoquinolines; Male; Microfilament Proteins; Nerve Degeneration; Neurons; Protein Binding; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Stereotaxic Techniques; Substantia Nigra; Time Factors; Tyrosine 3-Monooxygenase | 2012 |
Coupled intracerebral microdialysis and electrophysiology for the assessment of dopamine neuron function in vivo.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Brain Chemistry; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Dopaminergic Neurons; Electrophysiology; Extracellular Fluid; Male; Mice; Mice, Inbred C57BL; Microdialysis; Rats; Rats, Sprague-Dawley | 2012 |
Reduced forebrain serotonin transmission is causally involved in the development of compulsive cocaine seeking in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; 5,7-Dihydroxytryptamine; Animals; Behavior, Addictive; Cocaine; Conditioning, Operant; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Hydroxyindoleacetic Acid; Male; Prosencephalon; Punishment; Rats; Reinforcement Schedule; Reinforcement, Psychology; Self Administration; Serotonin; Serotonin Agents; Synaptic Transmission; Time Factors | 2012 |
Neuronal metabolomics by ion mobility mass spectrometry: cocaine effects on glucose and selected biogenic amine metabolites in the frontal cortex, striatum, and thalamus of the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cocaine; Corpus Striatum; Dopamine; Frontal Lobe; Glucose; Glycolysis; Hydroxyindoleacetic Acid; Limit of Detection; Male; Mass Spectrometry; Metabolomics; Pargyline; Principal Component Analysis; Rats; Rats, Sprague-Dawley; Serotonin; Thalamus | 2013 |
Decreased spontaneous activity in AMPK α2 muscle specific kinase dead mice is not caused by changes in brain dopamine metabolism.
Topics: 3,4-Dihydroxyphenylacetic Acid; AMP-Activated Protein Kinases; Animals; Cocaine; Corpus Striatum; Dopamine; Dopamine Uptake Inhibitors; Homovanillic Acid; Male; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Muscle, Skeletal; Mutation; Running | 2016 |
Neurochemical evidence that cocaine- and amphetamine-regulated transcript (CART) 55-102 peptide modulates the dopaminergic reward system by decreasing the dopamine release in the mouse nucleus accumbens.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Electric Stimulation; Extracellular Space; Homovanillic Acid; Humans; Male; Mice; Nerve Tissue Proteins; Norepinephrine; Nucleus Accumbens; Peptide Fragments; Phenylethyl Alcohol; Reward; Tissue Culture Techniques | 2017 |