3,4-dihydroxyphenylacetic acid has been researched along with carbidopa in 50 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (28.00) | 18.7374 |
| 1990's | 23 (46.00) | 18.2507 |
| 2000's | 10 (20.00) | 29.6817 |
| 2010's | 3 (6.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J | 1 |
| Davis, JM; Helgeson, E; Narasimhachari, N; Prakash, U | 1 |
| Borisenko, SA; Männistö, PT; Törnwall, M; Tuomainen, P; Tuominen, RK | 1 |
| Kaakkola, S; Männistö, PT; Tuomainen, P; Wurtman, RJ | 1 |
| Jenner, P; Marsden, CD; Rose, S | 3 |
| Carey, RJ | 1 |
| Wikberg, T | 1 |
| Capelli, M; Flamigni, C; Grossi, G; Paradisi, R; Pintore, A; Porcu, E; Venturoli, S | 1 |
| Brannan, T; Kaufmann, H; Knott, P; Yahr, M | 1 |
| Lehnert, H; Lombardi, F; Lorenzo, AV; Lown, B; Raeder, EA; Verrier, RL; Wurtman, RJ | 1 |
| Brannan, T; Kaufmann, H; Knott, P; Leung, L; Yahr, M | 1 |
| Cannon-Spoor, E; Chuang, LW; Costa, E; Freed, WJ; Karoum, F; Wyatt, RJ | 1 |
| Cohen, G; Spina, MB | 1 |
| Capelli, M; Fabbri, R; Flamigni, C; Grossi, G; Paradisi, R; Pasquali, R; Porcu, E; Venturoli, S | 1 |
| Kaakkola, S; Männistö, PT; Mäntylä, R; Nissinen, E; Vuorela, A | 1 |
| Joseph, MH; Kadam, BV; Risby, D | 1 |
| Lobo, RA; Shoupe, D | 1 |
| Calne, DB; Chuang, LW; Eisler, T; Karoum, F; Klein, DF; Liebowitz, MR; Quitkin, FM; Wyatt, RJ | 1 |
| Bird, ED; Langlais, PJ; McEntee, WJ | 1 |
| Nissinen, E; Taskinen, J | 1 |
| Gulliver, PA; Hagan, RM; Raxworthy, MJ | 1 |
| Kaakkola, S; Kask, A; Männistö, PT; Törnwall, M; Tuomainen, P | 1 |
| Lima, L; Urbina, M | 1 |
| Abe, T; Saheki, M; Takahashi, S; Tohgi, H; Tsukamoto, Y; Yamazaki, K | 1 |
| Demaggio, AJ; Havaich, M; Juneau, PL; Lewitt, PA; Loeffler, DA | 1 |
| Deleu, D; Ebinger, G; Michotte, Y; Sarre, S | 2 |
| Hossain, MA; Weiner, N | 1 |
| Baraldo, M; Benetello, P; Furlanut, M; Hassan, E; Zara, G | 1 |
| Gordin, A; Harjola, VP; Karlsson, M; Keränen, T; Korpela, K; Pentikäinen, PJ; Rita, H; Seppälä, L; Wikberg, T | 1 |
| Dethy, S; Goldman, S; Hildebrand, J; Laute, MA; Naini, AB; Przedborski, S; Raftopoulos, C | 1 |
| Ichikawa, M; Matsuyama, K; Nakashima, M; Nakashima, MN; Sakurai, M; Sasaki, H; Zhao, MF | 1 |
| Andre, MH; Bruguerolle, B; Grignon, S | 1 |
| Obata, T; Yamanaka, Y | 1 |
| Budygin, EA; Gaĭnetdinov, RR; Mannisto, PT; Raevskiĭ, KS | 1 |
| Gainetdinov, R; Huotari, M; Männistö, PT | 1 |
| Gerlach, M; Kuhn, W; Lehnfeld, R; Riederer, P; Sontag, KH; Waldmeier, P; Xiao, AY | 1 |
| Ferger, B; Schmidt, N; Schulz, JB; Teismann, P; Xia, XG | 1 |
| Abe, K; Miyatake, T; Ren, J; Sano, T; Shinohara, T; Taguchi, K; Utsunomiya, I; Wasai, T | 1 |
| Forsberg, M; Gogos, JA; Huotari, M; Hyttinen, J; Karayiorgou, M; Koponen, O; Männistö, PT; Raasmaja, A | 1 |
| Gluck, MR; Granson, H; Santana, LA; Yahr, MD | 1 |
| Ogawa, N; Tanaka, K | 1 |
| Carl, JL; Karimi, M; Loftin, S; Perlmutter, JS | 1 |
| Malmlöf, T; Schilström, B; Svensson, TH | 1 |
| García-Horsman, JA; Käenmäki, M; Kambur, O; Karvonen, E; Keisala, T; Kulesskaya, N; Männistö, PT; Rauvala, H; Tammimäki, A | 1 |
| Hoon, M; Petzer, A; Petzer, JP; Viljoen, F | 1 |
| Khan, SS; Mirza, T; Naeem, S; Najam, R; Sikandar, B | 1 |
1 trial(s) available for 3,4-dihydroxyphenylacetic acid and carbidopa
| Article | Year |
|---|---|
The effect of an increased ratio of carbidopa to levodopa on the pharmacokinetics of levodopa.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Carbidopa; Dopamine; Drug Interactions; Female; Humans; Kinetics; Levodopa; Male; Random Allocation | 1985 |
49 other study(ies) available for 3,4-dihydroxyphenylacetic acid and carbidopa
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection | 2009 |
Simultaneous determination by GC-MS-SIM of o-, m-, p-hydroxyphenylacetic acid, 3:4-dihydroxyphenylacetic acid and homovanillic acid in biological samples using a common selected ion.
Topics: 3,4-Dihydroxyphenylacetic Acid; Carbidopa; Chromatography, Gas; Homovanillic Acid; Humans; Levodopa; Mass Spectrometry; Methods; Phenylacetates | 1978 |
Effect of nitecapone and clorgyline, given intracerebro-ventricularly on L-dopa metabolism in the rat brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Carbidopa; Catechols; Cerebral Ventricles; Clorgyline; Corpus Striatum; Dopamine; Homovanillic Acid; Hypothalamus; Injections, Intraventricular; Levodopa; Male; Pentanones; Prolactin; Rats; Rats, Wistar; Thyrotropin | 1992 |
Effects of systemic carbidopa on dopamine synthesis in rat hypothalamus and striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Carbidopa; Corpus Striatum; Depression, Chemical; Dialysis; Dopamine; Homovanillic Acid; Hypothalamus; Injections, Intraperitoneal; Levodopa; Male; Perfusion; Rats; Rats, Inbred Strains; Tyrosine | 1992 |
Peripheral pharmacokinetic handling and metabolism of L-dopa in the rat: the effect of route of administration and carbidopa pretreatment.
Topics: 3,4-Dihydroxyphenylacetic Acid; Administration, Oral; Animals; Aorta, Thoracic; Carbidopa; Chromatography, High Pressure Liquid; Homovanillic Acid; Injections, Intravenous; Levodopa; Male; Rats; Rats, Inbred Strains; Tyrosine | 1991 |
Chronic L-dopa treatment in the unilateral 6-OHDA rat: evidence for behavioral sensitization and biochemical tolerance.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Carbidopa; Corpus Striatum; Denervation; Drug Tolerance; Functional Laterality; Homovanillic Acid; Levodopa; Male; Motor Activity; Oxidopamine; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome | 1991 |
Simultaneous determination of levodopa, its main metabolites and carbidopa in plasma by liquid chromatography.
Topics: 3,4-Dihydroxyphenylacetic Acid; Carbidopa; Chromatography, High Pressure Liquid; Chromatography, Liquid; Freeze Drying; Homovanillic Acid; Humans; Hydrogen-Ion Concentration; Levodopa; Solutions; Tyrosine | 1991 |
Evidence for a pathological reduction in brain dopamine metabolism in idiopathic hyperprolactinemia.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Brain; Carbidopa; Chromatography, High Pressure Liquid; Disulfiram; Dopamine; Dopamine beta-Hydroxylase; Epinephrine; Estradiol; Female; Follicle Stimulating Hormone; Growth Hormone; Homovanillic Acid; Humans; Hyperprolactinemia; Luteinizing Hormone; Methoxyhydroxyphenylglycol; Middle Aged; Norepinephrine; Progesterone; Prolactin; Testosterone; Thyrotropin; Vanilmandelic Acid | 1991 |
In vivo studies of striatal dopamine release and metabolism following administration of L-dopa.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Carbidopa; Corpus Striatum; Dopamine; Homovanillic Acid; Hydroxydopamines; Levodopa; Male; Neural Pathways; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Substantia Nigra; Synaptic Transmission | 1990 |
Increased release of brain serotonin reduces vulnerability to ventricular fibrillation in the cat.
Topics: 3,4-Dihydroxyphenylacetic Acid; 5-Hydroxytryptophan; Animals; Blood Pressure; Carbidopa; Cats; Coronary Disease; Female; Heart; Heart Rate; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Norepinephrine; Phenelzine; Serotonin; Ventricular Fibrillation | 1987 |
Intracerebral dialysis monitoring of striatal dopamine release and metabolism in response to L-dopa.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Carbidopa; Corpus Striatum; Dialysis; Dopamine; Homovanillic Acid; Levodopa; Male; Rats; Rats, Inbred Strains | 1989 |
D-dopa and L-dopa similarly elevate brain dopamine and produce turning behavior in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Carbidopa; Cerebral Ventricles; Dihydroxyphenylalanine; Dopamine; Homovanillic Acid; Levodopa; Male; Rats; Rats, Inbred Strains; Stereotyped Behavior; Structure-Activity Relationship | 1988 |
Exposure of striatal [corrected] synaptosomes to L-dopa increases levels of oxidized glutathione.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brocresine; Carbidopa; Catalase; Chromatography, High Pressure Liquid; Glutathione; Glutathione Disulfide; Hydrogen Peroxide; Levodopa; Male; Peroxides; Rats; Rats, Inbred Strains; Reserpine; Synaptosomes; tert-Butylhydroperoxide | 1988 |
The effect of carbidopa on plasma and muscle levels of L-dopa, dopamine, and their metabolites following L-dopa administration to rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Carbidopa; Chromatography, High Pressure Liquid; Dopamine; Drug Synergism; Homovanillic Acid; Levodopa; Muscles; Rats; Tyrosine | 1988 |
Evidence for a hypothalamic alteration of catecholamine metabolism in polycystic ovary syndrome.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adolescent; Adult; Carbidopa; Catecholamines; Dopamine; Female; Homovanillic Acid; Humans; Hypothalamus; Methoxyhydroxyphenylglycol; Polycystic Ovary Syndrome | 1988 |
Simple high-performance liquid chromatographic method for the concurrent determination of the amine metabolites vanillylmandelic acid, 3-methoxy-4-hydroxyphenylglycol, 5-hydroxyindoleacetic acid, dihydroxyphenylacetic acid and homovanillic acid in urine u
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenal Gland Neoplasms; Carbidopa; Chromatography, High Pressure Liquid; Glycols; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Methoxyhydroxyphenylglycol; Phenylacetates; Pheochromocytoma; Vanilmandelic Acid | 1981 |
Evidence for altered catecholamine metabolism in polycystic ovary syndrome.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adolescent; Adult; Carbidopa; Catecholamines; Drug Therapy, Combination; Female; Follicle Stimulating Hormone; Homovanillic Acid; Humans; Levodopa; Luteinizing Hormone; Methoxyhydroxyphenylglycol; Pituitary Hormone-Releasing Hormones; Polycystic Ovary Syndrome | 1984 |
Metabolism of (-) deprenyl to amphetamine and methamphetamine may be responsible for deprenyl's therapeutic benefit: a biochemical assessment.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Amphetamines; Biogenic Amines; Carbidopa; Depression; Drug Combinations; Female; Humans; Levodopa; Male; Methamphetamine; Middle Aged; Monoamine Oxidase; Parkinson Disease; Phenethylamines; Selegiline; Tyramine | 1982 |
Rapid liquid-chromatographic measurement of 3-methoxy-4-hydroxyphenylglycol and other monoamine metabolites in human cerebrospinal fluid.
Topics: 3-Methoxy-4-hydroxyphenylethanol; 3,4-Dihydroxyphenylacetic Acid; Aged; Carbidopa; Chromatography, High Pressure Liquid; Glycols; Homovanillic Acid; Humans; Levodopa; Male; Methoxyhydroxyphenylglycol; Vanilmandelic Acid | 1980 |
Simultaneous determination of carbidopa, levodopa and 3,4-dihydroxyphenyl-acetic acid using high-performance liquid chromatography with electrochemical detection.
Topics: 3,4-Dihydroxyphenylacetic Acid; Carbidopa; Chromatography, High Pressure Liquid; Dopamine; Electrochemistry; Humans; Levodopa; Phenylacetates | 1982 |
Benserazide and carbidopa as substrates of catechol-O-methyltransferase: new mechanism of action in Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benserazide; Benzyl Compounds; Carbidopa; Catechol O-Methyltransferase; Hydrazines; Kinetics; Liver; Parkinson Disease; S-Adenosylmethionine; Substrate Specificity; Swine | 1980 |
Comparison of two new inhibitors of catechol O-methylation on striatal dopamine metabolism: a microdialysis study in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amidines; Animals; Biogenic Monoamines; Carbidopa; Catechol O-Methyltransferase Inhibitors; Catechols; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Levodopa; Male; Microdialysis; Neostriatum; Nitriles; Pyridones; Rats; Rats, Wistar; Stereotaxic Techniques; Tryptophan; Tyrosine | 1994 |
Dopamine and serotonin turnover rate in the retina of rabbit, rat, goldfish, and Eugerres plumieri: light effects in goldfish and rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; 5-Hydroxytryptophan; alpha-Methyltyrosine; Animals; Carbidopa; Dopamine; Fenclonine; Goldfish; Homovanillic Acid; Hydroxyindoleacetic Acid; Levodopa; Light; Male; Methyltyrosines; Pargyline; Perciformes; Rabbits; Rats; Rats, Sprague-Dawley; Retina; Serotonin; Species Specificity | 1994 |
Effects of the catechol-O-methyltransferase inhibitor tolcapone in Parkinson's disease: correlations between concentrations of dopaminergic substances in the plasma and cerebrospinal fluid and clinical improvement.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aged; Antiparkinson Agents; Benzophenones; Carbidopa; Catechol O-Methyltransferase Inhibitors; Dopamine; Homovanillic Acid; Humans; Levodopa; Middle Aged; Nitrophenols; Parkinson Disease; Tolcapone; Tyrosine | 1995 |
Levodopa administration to normal rats: influence on striatal oxidized glutathione concentration.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Carbidopa; Corpus Striatum; Dose-Response Relationship, Drug; Glutathione; Glutathione Disulfide; Kinetics; Levodopa; Male; Rats; Rats, Sprague-Dawley; Time Factors | 1994 |
The effect of carbidopa on the pharmacokinetics and metabolism of intravenously administered levodopa in blood plasma and skeletal muscle.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Carbidopa; Dogs; Dopamine; Extracellular Space; Half-Life; Injections, Intravenous; Levodopa; Male; Microdialysis; Muscles; Tyrosine | 1993 |
Chronic administration does not alter the accumulation of L-dopa into muscle.
Topics: 3,4-Dihydroxyphenylacetic Acid; Administration, Oral; Animals; Carbidopa; Dopamine; Drug Therapy, Combination; Homovanillic Acid; Levodopa; Long-Term Care; Male; Metabolic Clearance Rate; Muscles; Rats; Rats, Wistar | 1994 |
Dopaminergic functional supersensitivity: effects of chronic L-dopa and carbidopa treatment in an animal model of Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biopterins; Brain Diseases; Carbidopa; Corpus Striatum; Cyclic AMP; Disease Models, Animal; Dopamine; Dopamine D2 Receptor Antagonists; Homovanillic Acid; Levodopa; Male; Oxidopamine; Parkinson Disease; Rats; Rats, Inbred F344; Receptors, Dopamine D1; Receptors, Dopamine D2; Sensitivity and Specificity; Substantia Nigra; Time Factors | 1993 |
Simultaneous monitoring of levodopa, dopamine and their metabolites in skeletal muscle and subcutaneous tissue in different pharmacological conditions using microdialysis.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Carbidopa; Chromatography, High Pressure Liquid; Dialysis; Dogs; Dopamine; Electrochemistry; Extracellular Space; Injections, Intravenous; Levodopa; Male; Methyldopa; Muscles; Skin | 1993 |
Plasma levels of levodopa and its main metabolites in parkinsonian patients after conventional and controlled-release levodopa-carbidopa associations.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aged; Antiparkinson Agents; Blood-Brain Barrier; Carbidopa; Delayed-Action Preparations; Dopamine; Dose-Response Relationship, Drug; Drug Combinations; Female; Homovanillic Acid; Humans; Levodopa; Male; Middle Aged; Neurologic Examination; Parkinson Disease; Tyrosine | 1993 |
The effect of catechol-O-methyl transferase inhibition by entacapone on the pharmacokinetics and metabolism of levodopa in healthy volunteers.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Carbidopa; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Catechols; Electrocardiography; Half-Life; Homovanillic Acid; Humans; Levodopa; Male; Nitriles; Reference Values; Tyrosine | 1993 |
Slow increase of homovanillic acid in cerebrospinal fluid after levodopa administration.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aged; Antiparkinson Agents; Carbidopa; Drug Administration Schedule; Drug Combinations; Female; Homovanillic Acid; Humans; Hydrocephalus; Levodopa; Male; Middle Aged | 1996 |
In vivo microdialysis to determine the relative pharmacokinetics of drugs.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antiparkinson Agents; Benserazide; Brain Chemistry; Carbidopa; Chromatography, High Pressure Liquid; Dopamine; Drug Interactions; Electrochemistry; Homovanillic Acid; Levodopa; Male; Methoxyhydroxyphenylglycol; Microdialysis; Neostriatum; Rats; Rats, Wistar | 1996 |
Circadian phase dependent pharmacokinetics of L-dopa, its main metabolites (3-OMD, HVA, DOPAC) and carbidopa in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Area Under Curve; Carbidopa; Circadian Rhythm; Half-Life; Homovanillic Acid; Levodopa; Male; Methyldopa; Rats; Rats, Wistar | 1996 |
Protective effect of carbidopa on hydroxyl radical generation in the rat striatum by dopamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Carbidopa; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibitors; Dopamine; Dopamine Agents; Free Radicals; Hydroxides; Levodopa; Male; Microdialysis; Neostriatum; Neuroprotective Agents; Rats; Rats, Wistar; Sodium Salicylate | 1996 |
[Effect of subchronic administration of tolcapone on release of striatum dopamine and its metabolites induced by L-DOPA and carbidopa].
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antiparkinson Agents; Benzophenones; Carbidopa; Catechol O-Methyltransferase Inhibitors; Corpus Striatum; Dopamine; Dopamine Agents; Drug Synergism; Enzyme Inhibitors; Homovanillic Acid; Levodopa; Male; Nitrophenols; Rats; Rats, Wistar; Tolcapone | 1998 |
Microdialysis studies on the action of tolcapone on pharmacologically-elevated extracellular dopamine levels in conscious rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Benzophenones; Carbidopa; Catechol O-Methyltransferase; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Drug Interactions; Enzyme Inhibitors; Extracellular Space; Haloperidol; Homovanillic Acid; Levodopa; Male; Microdialysis; Nitrophenols; Piperazines; Rats; Rats, Wistar; Time Factors; Tolcapone; Visual Cortex | 1999 |
The central catechol-O-methyltransferase inhibitor tolcapone increases striatal hydroxyl radical production in L-DOPA/carbidopa treated rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antiparkinson Agents; Benzophenones; Carbidopa; Catechol O-Methyltransferase Inhibitors; Catechols; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Hydroxyl Radical; Levodopa; Male; Microdialysis; Nitriles; Nitrophenols; Oxidative Stress; Parkinsonian Disorders; Rats; Rats, Wistar; Tolcapone | 2001 |
Dopamine mediates striatal malonate toxicity via dopamine transporter-dependent generation of reactive oxygen species and D2 but not D1 receptor activation.
Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Methyltyrosine; Animals; Benzazepines; Brain Diseases; Carbidopa; Carrier Proteins; Corpus Striatum; Dizocilpine Maleate; Dopamine; Dopamine D2 Receptor Antagonists; Dopamine Plasma Membrane Transport Proteins; Enzyme Inhibitors; Homovanillic Acid; Levodopa; Male; Malonates; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Neuropeptides; Oxidopamine; Rats; Rats, Wistar; Reactive Oxygen Species; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate; Reserpine; Succinate Dehydrogenase; Sulpiride; Vesicular Biogenic Amine Transport Proteins; Vesicular Monoamine Transport Proteins | 2001 |
Stereoselective effect of (R)- and (S)-1-methyl-1,2,3,4-tetrahydroisoquinolines on a mouse model of Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Carbidopa; Cell Count; Disease Models, Animal; Dopamine; Dopamine Antagonists; Drug Interactions; Homovanillic Acid; Hydroxyindoleacetic Acid; Hypokinesia; Immunohistochemistry; Isoquinolines; Levodopa; Male; Mice; Mice, Inbred C57BL; Neurons; Neuroprotective Agents; Neurotoxins; Parkinsonian Disorders; Serotonin; Stereoisomerism; Substantia Nigra; Tetrahydroisoquinolines; Tyrosine 3-Monooxygenase | 2001 |
Brain catecholamine metabolism in catechol-O-methyltransferase (COMT)-deficient mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Anesthesia; Animals; Carbidopa; Catechol O-Methyltransferase; Corpus Striatum; Dopamine; Dopamine Agents; Female; Homovanillic Acid; Levodopa; Male; Methoxyhydroxyphenylglycol; Methyldopa; Mice; Mice, Inbred C57BL; Mice, Knockout; Microdialysis; Norepinephrine | 2002 |
Novel dopamine releasing response of an anti-convulsant agent with possible anti-Parkinson's activity.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Animals; Antiparkinson Agents; Behavior, Animal; Carbidopa; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Agents; Homovanillic Acid; Isoxazoles; Levodopa; Microdialysis; Oxidopamine; Parkinson Disease; Rats; Zonisamide | 2004 |
Dopamine agonist cabergoline inhibits levodopa-induced caspase activation in 6-OHDA-lesioned mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Cabergoline; Carbidopa; Caspases; Disease Models, Animal; Dopamine; Dopamine Agents; Dopamine Agonists; Drug Combinations; Drug Interactions; Enzyme Activation; Ergolines; Glutathione; Homovanillic Acid; Levodopa; Male; Mice; Mice, Inbred ICR; Neurotoxicity Syndromes; Oxidopamine; Thiobarbituric Acid Reactive Substances | 2005 |
Modified high-performance liquid chromatography with electrochemical detection method for plasma measurement of levodopa, 3-O-methyldopa, dopamine, carbidopa and 3,4-dihydroxyphenyl acetic acid.
Topics: 3,4-Dihydroxyphenylacetic Acid; Calibration; Carbidopa; Chromatography, High Pressure Liquid; Dopamine; Electrochemistry; Levodopa; Tyrosine | 2006 |
Altered behavioural and neurochemical profile of L-DOPA following deuterium substitutions in the molecule.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Brain Chemistry; Carbidopa; Deuterium; Dopamine; Dopamine Agents; Levodopa; Male; Microdialysis; Motor Activity; Rats; Rats, Wistar; Time Factors | 2008 |
Effect of S-COMT deficiency on behavior and extracellular brain dopamine concentrations in mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Brain; Carbidopa; Catechol O-Methyltransferase; Dopamine; Drug Combinations; Extracellular Space; Female; Levodopa; Male; Methylation; Mice; Mice, Inbred C57BL; Mice, Knockout; Microdialysis; Mutation; Phenotype; Sensory Gating; Sex Factors; Social Dominance | 2010 |
The Design and Evaluation of an l-Dopa-Lazabemide Prodrug for the Treatment of Parkinson's Disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biological Availability; Carbidopa; Corpus Striatum; Dopamine; Drug Combinations; HeLa Cells; Humans; Levodopa; Male; Mice, Inbred C57BL; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Parkinson Disease; Permeability; Picolinic Acids; Prodrugs; Solubility; Structure-Activity Relationship | 2017 |
Neuroprotective effect of diclofenac on chlorpromazine induced catalepsy in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Carbidopa; Catalepsy; Chlorpromazine; Corpus Striatum; Diclofenac; Dopamine; Female; Levodopa; Male; Motor Activity; Neuroprotective Agents; Rats; Rats, Wistar | 2019 |