3,4-dihydroxyphenylacetic acid has been researched along with 3-methoxytyrosine in 30 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (16.67) | 18.7374 |
| 1990's | 18 (60.00) | 18.2507 |
| 2000's | 7 (23.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lindén, IB; Nissinen, E; Pohto, P; Schultz, E | 1 |
| Bjurling, P; Gillberg, PG; Långström, B; Miwa, S; Odano, I; Watanabe, Y; Yumoto, N | 1 |
| Kaakkola, S; Männistö, PT; Tuomainen, P; Wurtman, RJ | 1 |
| Jenner, P; Marsden, CD; Rose, S | 2 |
| Wikberg, T | 1 |
| Antonin, KH; Bieck, PR; Nilsson, E | 1 |
| Cohen, Y; el Gemayel, G; Jacquot, C; Prioux-Guyonneau, M; Trouvin, JH | 1 |
| Huot, S; Palfreyman, MG; Vitali, P; Wagner, J; Zraika, M | 1 |
| Aguado, EG; de Yebenes, JG; Mena, MA | 1 |
| Fahn, S; Reches, A | 1 |
| Deleu, D; Ebinger, G; Michotte, Y; Sarre, S; Van Belle, K | 1 |
| Kaakkola, S; Kask, A; Männistö, PT; Törnwall, M; Tuomainen, P | 1 |
| Bertrand, A; Weil-Fugazza, J | 1 |
| Abe, T; Saheki, M; Takahashi, S; Tohgi, H; Tsukamoto, Y; Yamazaki, K | 1 |
| Aguirre, J; Armando, I; Barontini, M; Nowicki, S | 1 |
| Deleu, D; Ebinger, G; Michotte, Y; Sarre, S | 1 |
| Baraldo, M; Benetello, P; Furlanut, M; Hassan, E; Zara, G | 1 |
| Gordin, A; Harjola, VP; Karlsson, M; Keränen, T; Korpela, K; Pentikäinen, PJ; Rita, H; Seppälä, L; Wikberg, T | 1 |
| Chang, WY; Webster, RA | 1 |
| Achilli, G; Banting, A; Banting, S; Le Bars, D; Weil-Fugazza, J | 1 |
| Brannan, T; Prikhojan, A; Yahr, MD | 1 |
| Crevoisier, C; Dingemanse, J; Kleinbloesem, CH; Wood, ND; Zürcher, G | 1 |
| Jackson, M; Jenner, P; Treseder, SA | 1 |
| Jenner, P; Rose, S; Treseder, SA | 1 |
| Hainzl, D; Loureiro, AI; Parada, A; Soares-da-Silva, P; Vieira-Coelho, MA | 1 |
| Buhmann, C; Oechsner, M; Strauss, J; Stuerenburg, HJ | 1 |
| Schmidt, WJ; Srinivasan, J | 2 |
| Carl, JL; Karimi, M; Loftin, S; Perlmutter, JS | 1 |
1 trial(s) available for 3,4-dihydroxyphenylacetic acid and 3-methoxytyrosine
| Article | Year |
|---|---|
Pharmacodynamics of benserazide assessed by its effects on endogenous and exogenous levodopa pharmacokinetics.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Antiparkinson Agents; Benserazide; Carboxy-Lyases; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Humans; Levodopa; Male; Middle Aged; Tyrosine | 1997 |
29 other study(ies) available for 3,4-dihydroxyphenylacetic acid and 3-methoxytyrosine
| Article | Year |
|---|---|
Biochemical and pharmacological properties of a peripherally acting catechol-O-methyltransferase inhibitor entacapone.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Catechol O-Methyltransferase Inhibitors; Catechols; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Duodenum; Erythrocytes; Homovanillic Acid; In Vitro Techniques; Liver; Male; Nitriles; Rats; Rats, Wistar; Tyrosine | 1992 |
Assessment of dopamine and its metabolites in the intracellular and extracellular compartments of the rat striatum after peripheral administration of L-[11C]dopa.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Extracellular Space; Homovanillic Acid; Injections, Intravenous; Intracellular Fluid; Kinetics; Levodopa; Male; Radioisotope Dilution Technique; Rats; Rats, Inbred Strains; Tyrosine | 1992 |
Effects of systemic carbidopa on dopamine synthesis in rat hypothalamus and striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Carbidopa; Corpus Striatum; Depression, Chemical; Dialysis; Dopamine; Homovanillic Acid; Hypothalamus; Injections, Intraperitoneal; Levodopa; Male; Perfusion; Rats; Rats, Inbred Strains; Tyrosine | 1992 |
Peripheral pharmacokinetic handling and metabolism of L-dopa in the rat: the effect of route of administration and carbidopa pretreatment.
Topics: 3,4-Dihydroxyphenylacetic Acid; Administration, Oral; Animals; Aorta, Thoracic; Carbidopa; Chromatography, High Pressure Liquid; Homovanillic Acid; Injections, Intravenous; Levodopa; Male; Rats; Rats, Inbred Strains; Tyrosine | 1991 |
Simultaneous determination of levodopa, its main metabolites and carbidopa in plasma by liquid chromatography.
Topics: 3,4-Dihydroxyphenylacetic Acid; Carbidopa; Chromatography, High Pressure Liquid; Chromatography, Liquid; Freeze Drying; Homovanillic Acid; Humans; Hydrogen-Ion Concentration; Levodopa; Solutions; Tyrosine | 1991 |
Effect of the new selective COMT inhibitor CGP 28014 A on the formation of 3-O-methyldopa (3OMD) in plasma of healthy subjects.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amidines; Catechol O-Methyltransferase Inhibitors; Dihydroxyphenylalanine; Homovanillic Acid; Humans; Male; Pyridones; Tyrosine | 1990 |
Re-evaluation of the L-dopa loading effect on dopamine metabolism in rat striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benserazide; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Drug Therapy, Combination; Homovanillic Acid; Levodopa; Male; Rats; Rats, Inbred Strains; Tyrosine | 1986 |
The effect of carbidopa on plasma and muscle levels of L-dopa, dopamine, and their metabolites following L-dopa administration to rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Carbidopa; Chromatography, High Pressure Liquid; Dopamine; Drug Synergism; Homovanillic Acid; Levodopa; Muscles; Rats; Tyrosine | 1988 |
Simultaneous determination of 3,4-dihydroxyphenylalanine, 5-hydroxytryptophan, dopamine, 4-hydroxy-3-methoxyphenylalanine, norepinephrine, 3,4-dihydroxyphenylacetic acid, homovanillic acid, serotonin, and 5-hydroxyindoleacetic acid in rat cerebrospinal fl
Topics: 3,4-Dihydroxyphenylacetic Acid; 5-Hydroxytryptophan; Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Methyltyrosines; Norepinephrine; Rats; Rats, Inbred Strains; Serotonin; Tryptophan; Tyrosine | 1982 |
Monoamine metabolites in human cerebrospinal fluid. HPLC/ED method.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alzheimer Disease; Chromatography, High Pressure Liquid; Depression; Dihydroxyphenylalanine; Electrochemistry; Glycols; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Methoxyhydroxyphenylglycol; Parkinson Disease; Phenylacetates; Subarachnoid Hemorrhage; Tryptophan; Tyrosine | 1984 |
3-O-methyldopa blocks dopa metabolism in rat corpus striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Homovanillic Acid; Levodopa; Male; Methyltyrosines; Parkinson Disease; Rats; Rats, Inbred Strains; Tyrosine | 1982 |
Quantitative microdialysis for studying the in vivo L-DOPA kinetics in blood and skeletal muscle of the dog.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Blood Proteins; Calibration; Dialysis; Dogs; Dopamine; Injections, Intramuscular; Injections, Intravenous; Levodopa; Male; Methyldopa; Microchemistry; Muscle, Skeletal; Protein Binding; Reference Standards; Reproducibility of Results; Tyrosine | 1995 |
Comparison of two new inhibitors of catechol O-methylation on striatal dopamine metabolism: a microdialysis study in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amidines; Animals; Biogenic Monoamines; Carbidopa; Catechol O-Methyltransferase Inhibitors; Catechols; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Levodopa; Male; Microdialysis; Neostriatum; Nitriles; Pyridones; Rats; Rats, Wistar; Stereotaxic Techniques; Tryptophan; Tyrosine | 1994 |
Sympathectomy does not modify the levels of dopa or dopamine in the rat dorsal root ganglion.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Dopamine; Electrochemistry; Ganglia, Spinal; Guanethidine; Homovanillic Acid; Male; Rats; Rats, Sprague-Dawley; Sympathectomy, Chemical; Tyrosine | 1995 |
Effects of the catechol-O-methyltransferase inhibitor tolcapone in Parkinson's disease: correlations between concentrations of dopaminergic substances in the plasma and cerebrospinal fluid and clinical improvement.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aged; Antiparkinson Agents; Benzophenones; Carbidopa; Catechol O-Methyltransferase Inhibitors; Dopamine; Homovanillic Acid; Humans; Levodopa; Middle Aged; Nitrophenols; Parkinson Disease; Tolcapone; Tyrosine | 1995 |
A decreased tubular uptake of dopa results in defective renal dopamine production in aged rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Aromatic-L-Amino-Acid Decarboxylases; Biological Transport; Catechol O-Methyltransferase; Dihydroxyphenylalanine; Dopamine; Kidney; Kidney Cortex; Male; Microvilli; Monoamine Oxidase; Norepinephrine; Rats; Rats, Wistar; Regression Analysis; Tyrosine | 1995 |
The effect of carbidopa on the pharmacokinetics and metabolism of intravenously administered levodopa in blood plasma and skeletal muscle.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Carbidopa; Dogs; Dopamine; Extracellular Space; Half-Life; Injections, Intravenous; Levodopa; Male; Microdialysis; Muscles; Tyrosine | 1993 |
Plasma levels of levodopa and its main metabolites in parkinsonian patients after conventional and controlled-release levodopa-carbidopa associations.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aged; Antiparkinson Agents; Blood-Brain Barrier; Carbidopa; Delayed-Action Preparations; Dopamine; Dose-Response Relationship, Drug; Drug Combinations; Female; Homovanillic Acid; Humans; Levodopa; Male; Middle Aged; Neurologic Examination; Parkinson Disease; Tyrosine | 1993 |
The effect of catechol-O-methyl transferase inhibition by entacapone on the pharmacokinetics and metabolism of levodopa in healthy volunteers.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Carbidopa; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Catechols; Electrocardiography; Half-Life; Homovanillic Acid; Humans; Levodopa; Male; Nitriles; Reference Values; Tyrosine | 1993 |
Effects of 3-O-methyl on L-dopa-facilitated synthesis and efflux of dopamine from rat striatal slices.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antiparkinson Agents; Cerebrospinal Fluid; Corpus Striatum; Dopamine; Drug Interactions; Levodopa; Male; Potassium Chloride; Rats; Rats, Sprague-Dawley; Tyrosine | 1995 |
Tyrosine and tryptophan derivatives in pig lumbar cerebrospinal fluid. Effects of subchronic administration of dopa associated with benserazide.
Topics: 3,4-Dihydroxyphenylacetic Acid; Administration, Oral; Animals; Benserazide; Drug Interactions; Female; Homovanillic Acid; Hydroxyindoleacetic Acid; Kynurenine; Levodopa; Male; Methoxyhydroxyphenylglycol; Normetanephrine; Swine; Tryptamines; Tryptophan; Tyrosine | 1996 |
An in vivo comparison of the capacity of striatal versus extrastriatal brain regions to form dopamine from exogenously administered L-dopa.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biotransformation; Brain Chemistry; Cerebellum; Dopamine; Dopamine Agents; Extracellular Space; Hydroxyindoleacetic Acid; Levodopa; Male; Microdialysis; Neostriatum; Occipital Lobe; Rats; Rats, Sprague-Dawley; Tyrosine | 1996 |
The effects of central aromatic amino acid DOPA decarboxylase inhibition on the motor actions of L-DOPA and dopamine agonists in MPTP-treated primates.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Behavior, Animal; Callithrix; Dopamine; Dopamine Agonists; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Hydrazines; Levodopa; Male; Motor Activity; Quinolones; Quinpirole; Thiophenes; Tyrosine | 2000 |
The central aromatic amino acid DOPA decarboxylase inhibitor, NSD-1015, does not inhibit L-DOPA-induced circling in unilateral 6-OHDA-lesioned-rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Behavior, Animal; Biogenic Monoamines; Brain; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Dopamine Agents; Dopamine Antagonists; Drug Combinations; Enzyme Inhibitors; Haloperidol; Homovanillic Acid; Hydrazines; Levodopa; Male; Medial Forebrain Bundle; Oxidopamine; Rats; Rats, Wistar; Stereotyped Behavior; Tyrosine | 2001 |
BIA 3-202, a novel catechol-O-methyltransferase inhibitor, enhances the availability of L-DOPA to the brain and reduces its O-methylation.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acetophenones; Animals; Biological Availability; Brain; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Homovanillic Acid; Levodopa; Male; Methylation; Rats; Rats, Wistar; Time Factors; Tyrosine | 2001 |
COMT-inhibition increases serum levels of dihydroxyphenylacetic acid (DOPAC) in patients with advanced Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aged; Aged, 80 and over; Antiparkinson Agents; Benzophenones; Catechol O-Methyltransferase Inhibitors; Dihydroxyphenylalanine; Disease Progression; Dose-Response Relationship, Drug; Female; Homovanillic Acid; Humans; Levodopa; Male; Middle Aged; Nitrophenols; Parkinson Disease; Tolcapone; Tyrosine | 2002 |
Potentiation of parkinsonian symptoms by depletion of locus coeruleus noradrenaline in 6-hydroxydopamine-induced partial degeneration of substantia nigra in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Animals; Behavior, Animal; Benzylamines; Catalepsy; Disease Models, Animal; Dopamine; Dopamine Antagonists; Drug Interactions; Haloperidol; Hippocampus; Homovanillic Acid; Hypothalamus; Locus Coeruleus; Male; Medial Forebrain Bundle; Nerve Degeneration; Neurotoxins; Norepinephrine; Oxidopamine; Parkinsonian Disorders; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Reaction Time; Serotonin; Substantia Nigra; Thalamus; Tyrosine | 2003 |
Behavioral and neurochemical effects of noradrenergic depletions with N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine in 6-hydroxydopamine-induced rat model of Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Amphetamine; Analysis of Variance; Animals; Basal Ganglia; Behavior, Animal; Benzylamines; Brain Chemistry; Catalepsy; Disease Models, Animal; Dopamine; Dopamine Agents; Homovanillic Acid; Levodopa; Locus Coeruleus; Male; Motor Activity; Norepinephrine; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Serotonin; Statistics, Nonparametric; Tyrosine | 2004 |
Modified high-performance liquid chromatography with electrochemical detection method for plasma measurement of levodopa, 3-O-methyldopa, dopamine, carbidopa and 3,4-dihydroxyphenyl acetic acid.
Topics: 3,4-Dihydroxyphenylacetic Acid; Calibration; Carbidopa; Chromatography, High Pressure Liquid; Dopamine; Electrochemistry; Levodopa; Tyrosine | 2006 |