Compounds > 3,4-dihydroxyphenylacetic acid

3,4-dihydroxyphenylacetic acid and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

3,4-dihydroxyphenylacetic acid has been researched along with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in 242 studies

Research

Studies (242)

Timeframe	Studies, this research(%)	All Research%
pre-1990	80 (33.06)	18.7374
1990's	67 (27.69)	18.2507
2000's	64 (26.45)	29.6817
2010's	31 (12.81)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Wesemann, W	1
DiStefano, L; Pope, A; Schneider, JS; Simpson, K; Smith, MG; Taggart, J	1
Del Río, J; Kupsch, A; Luquin, MR; Obeso, JA; Oertel, W; Oset, C; Pérez-Otaño, I; Trinidad Herrero, M	1
Hansen, S; Krieger, C; Perry, TL; Tabatabaei, A	1
Schneider, JS	2
Bagchi, SP	2
Dalia, A; Fitkin, JG; Hadjiconstantinou, M; Neff, NH	1
Johannessen, JN; Markey, SP; Sobotka, TJ; Weise, VK	1
Hallberg, A; Nilsson, K; Pileblad, E; Tunek, A	1
Bankiewicz, KS; Hsiao, J; Mefford, I; Skirboll, S; Wang, J	1
Mizutani, N; Nagatsu, T; Naoi, M; Ochi, N; Ohya, Y; Watanabe, K	1
Chan, WW; Rausch, WD; Riederer, P; Schallauer, E; Weiser, M	1
Gerlach, M; Mihatsch, W; Przuntek, H; Riederer, P; Russ, H	1
Bonuccelli, U; Fariello, R; Garant, D	1
Chong, PN; de Ceballos, ML; Jenner, P; Marsden, CD; Rose, S; Taylor, MD	1
De Ceballos, ML; Del Río, J; Herrero, MT; Luquin, MR; Obeso, JA; Oset, C; Pérez-Otaño, I	1
Barrio, JR; Hoffman, JM; Melega, WP; Phelps, ME; Schneider, JS	1
Blandina, P; Burns, RS; Green, JP; Khandelwal, JK; Morrishow, AM; Prell, GD	1
Otto, D; Unsicker, K	1
Date, I; Felten, DL; Felten, SY	1
DeLanney, LE; Di Monte, DA; Finnegan, KT; Forno, LS; Irwin, I; Langston, JW	1
Fuller, RW; Hemrick-Luecke, SK; Robertson, DW	3
Albert, ML; Davoudi, H; Durso, R; Fazzini, E; Szabo, GK	1
Bédard, PJ; Di Paolo, T; Rouillard, C	1
Goldstein, DS; Johannessen, JN; Markey, SP; Oliver, J	1
Carr, LA; Rowell, PP	1
Bruno, JP; Hadjiconstantinou, M; Neff, NH; Weihmuller, FB	1
Henning, K; Pindur, U; Przuntek, H; Russ, H	1
Bradbury, AJ; Costall, B; Domeney, AM; Jenner, PG; Marsden, CD; Naylor, RJ; Testa, B	1
Bradbury, AJ; Costall, B; Domeney, AM; Jenner, PJ; Marsden, CD; Naylor, RJ	1
Bédard, P; Boucher, R; Daigle, M; Di Paolo, T	1
Agid, Y; Benoliel, JT; Cesselin, F; Javoy-Agid, F; Jenner, P; Marsden, CD; Mauborgne, A; Rose, S; Taquet, H	1
DeMattei, M; Fariello, RG; Ferraro, TN; Golden, GT; Hare, TA	1
Bacon, JP; Hanselman, DS; Johannessen, JN; Markey, CJ; Markey, SP; Savitt, JM; Weisz, A	1
Bonuccelli, U; Corsini, GU; Kopin, IJ; Schinelli, S; Zuddas, A	1
Audsley, AR; Sirinathsinghji, DJ; Whittington, PE	1
Arai, Y; Kinemuchi, H; Kisara, K; Matsumura, T; Sakuma, I; Satoh, N; Tadano, T	1
Arora, PK; Blue, P; Harik, SI; Iacofano, LA; Sayre, LM; Schmidley, JW	1
Sheng, JG; Tang, QM; Xu, DL; Xu, XR; Yu, HZ	1
Agid, Y; Benoliel, JJ; Javoy-Agid, F; Jenner, P; Legrand, JC; Marsden, CD; Mauborgne, A; Nomoto, M; Rose, S; Taquet, H	1
Hashim, A; Lajtha, A; Sershen, H; Wiener, HL	1
Jenner, P; Kelly, E; Kilpatrick, G; Marsden, CD; Nomoto, M; Rose, S	1
Albanese, A; Chivers, JK; Chong, PN; Jenner, P; Marsden, CD; Rose, S; Ueki, A	1
Gibb, WR; Jackson, EA; Jenner, P; Marsden, CD; Nomoto, M; Rose, S	1
Bizière, K; Guillaumin, JM; Kan, JP; Renoux, G; Renoux, M; Steinberg, R	1
Hadjiconstantinou, M; Mariani, AP; Neff, NH	1
Bacon, JP; Burns, RS; Chiueh, CC; Garrick, NA; Johannessen, JN; Kopin, IJ; Markey, SP; Parisi, JE; Weise, VK	1
Fuller, RW; Hemrick-Luecke, SK	5
Deutch, AY; Roth, RH; Sladek, JR; Yurek, DM	1
Eckhardt, H; Henning, K; Przuntek, H; Russ, H	1
Collins, MA; Neafsey, EJ	1
Bruno, JP; Hadjiconstantinou, M; Weihmuller, FB	2
Foulks, JG; Ito, M; Jones, K; Kish, SJ; Perry, TL; Wall, RA; Wright, JM; Yong, VW	1
Heikkila, RE; Mayer, RA; Walters, AS	1
Gibb, JW; Hanson, GR; Matsuda, LA; Schmidt, CJ	1
Fujitake, J; Kuno, S; Mori, S; Sano, Y	1
Bédard, PJ; Di Paolo, T; Falardeau, P	1
Chiueh, CC; Corsini, GU; Kopin, IJ; Pintus, S; Weiss, JF	1
Duvoisin, RC; Heikkila, RE; Nicklas, WJ	1
Bixler, GB; Dunn, AJ; Eaker, EY; Mathias, JR; Moreshead, WV	1
Saitoh, T	1
Heavens, RP; McBride, CS; Sirinathsinghji, DJ	1
Fukuda, H; Fukuyama, H; Hara, K; Kameyama, M; Nakamura, S	1
Domino, EF; Greenberg, HS; Hood, TW	1
Bodis-Wollner, I; Chung, E; Dvorzniak, M; Ghilardi, MF; Glover, A; Onofrj, M	1
Bédard, PJ; Bouchard, S; Boucher, R; Di Paolo, T; Falardeau, P	1
Hadjiconstantinou, M; Neff, NH	1
Chiba, K; Ishizaki, T; Kato, Y; Kubota, E; Miyakawa, T	1
Ambrosio, S; Blesa, R; Gual, A; Mahy, N; Mintenig, GM; Palacios-Araus, L	1
Masaki, N; Nishikawa, S; Shimoda, K; Takahashi, K; Urakami, K	1
Chang, GD; Ramirez, VD	2
de Vries, J; Fries, DS; Hazelhoff, B; Horn, AS	1
Arora, PK; Harik, SI; Iacofano, LA; Sayre, LM	1
Jonsson, G; Scarnati, E; Schultz, W; Sundström, E; Tsutsumi, T	1
Cantrell, BE; Fuller, RW; Hemrick-Luecke, SK; Reel, JK; Zimmerman, DM	1
Brooks, BA; Eidelberg, E; Kokemoor, RH; Morgan, WW; Walden, JG	1
Hashim, A; Lajtha, A; Mason, MF; Reith, ME; Sershen, H	1
Heikkila, RE; Sonsalla, PK	2
Deutch, AY; Elsworth, JD; Redmond, DE; Roth, RH; Sladek, JR	2
Heikkila, RE; Sonsalla, PK; Youngster, SK	1
Mizuno, Y; Niijima, K; Saitoh, T	1
Cohen, G; Mytilineou, C	1
Cheng, BY; Christensen, MA; Collins, MA; Hurley-Gius, D; Hurley-Gius, K; Neafsey, EJ; Pronger, DA; Ung-Chhun, NA	1
Neumeyer, JL; Szabo, S	1
Hansen, S; Jones, K; Perry, TL	1
Hashim, A; Lajtha, A; Sershen, H	1
Clavier, RM; Foulks, JG; Jones, K; Perry, TL; Wall, RA; Wright, JM; Yong, VW	1
Freedman, R; Hoffer, B; Johnson, S; Jonsson, G; Mefford, I; Olson, L; Sundström, E	1
Heikkila, RE	1
Duvoisin, RC; Heikkila, RE; Hess, A	2
Bocchetta, A; Corsini, GU; Del Zompo, M; Piccardi, MP; Pintus, S	1
Carlsson, A; Nissbrandt, H; Pileblad, E	1
Burns, RS; Chiueh, CC; Johannessen, JN; Kopin, IJ; Markey, SP; Pert, A	1
Jenner, P; Kelly, E; Kilpatrick, G; Lees, A; Marsden, CD; Rose, S; Rupniak, NM	1
Boyce, S; Jenner, P; Kelly, E; Marsden, CD; Reavill, C	1
Cabbat, FS; Duvoisin, RC; Heikkila, RE; Manzino, L	1
Gupta, M; Wiener, HL	1
Distefano, L; Schneider, JS	2
Block, F; Clement, HW; Grote, C; Sontag, KH; Wesemann, W	1
Gerlach, M; Przuntek, H; Riederer, P; Russ, H; Stasch, JP; Traber, J; Winker, J; Witzmann, K	1
Boireau, A; Bordier, F; Doble, A; Dubédat, P; Durand, G; Meunier, M; Miquet, JM; Peny, C	1
Andersen, JK; Beal, MF; Breakefield, XO; Frim, DM; Isacson, O	1
Fukuda, T; Fukuzaki, K; Irifune, M; Nomoto, M	1
Ambrosio, S; Baron, S; Mahy, N; Perez, V; Unzeta, M	1
De Natale, G; Desole, MS; Enrico, P; Esposito, G; Fresu, L; Miele, E; Miele, M; Migheli, R	1
Berrian, J; DiStefano, L; Schneider, JS; Smith, MG	1
Giovanni, A; Heikkila, RE; Sieber, BA; Sonsalla, PK	1
Giovanni, A; Heikkila, RE; Sonsalla, PK	1
Del Río, J; Herrero, MT; Luquin, MR; Obeso, JA; Oset, C; Pérez-Otaño, I	1
Tai, MY; Tsai, HW; Tsai, YF	1
Albanese, A; Colosimo, C; Granata, R; Gregori, B; Piccardi, MP; Tonali, P	1
Hasegawa, E; Murai, Y; Oishi, T	1
Fuller, RW; Hemrick-Luecke, SK; Mitch, CH; Quimby, SJ	1
Cosi, C; Harvey-White, JD; Mitsuo, K; Schwartz, JP	1
Cass, WA; Gash, DM; Gerhardt, GA; Henson, M; Hoffer, BJ; Hudson, J; Ovadia, A; Zhang, Z	1
Dluzen, DE	1
Beal, MF; Brouillet, E; Dolan, R; Ferrante, R; Hantraye, P; Matthews, RT; Palfi, S	1
Canini, F; Lalonde, R; Messaoudi, M; Minn, A; Tricoire, A	1
Ali, SF; Cadet, JL; Freyaldenhoven, TE	1
Kitamura, Y; Kohno, Y; Nakazawa, M; Nomura, Y	1
Jiang, DH; Lan, J	1
Boireau, A; Bordier, F; Dubédat, P; Impérato, A; Pény, C	1
Ju, J; Xi, G; Zhu, W	1
Arnold, LA; Blanchet, PJ; Chase, TN; Hyland, K; Konitsiotis, S; Pettigrew, KD	1
Andreassen, OA; Beal, MF; Bonventre, JV; Chin, MR; Ferrante, RJ; Klivenyi, P; Wermer, M	1
Flint Beal, M; Klivenyi, P; Oberley, T; St Clair, D; Wermer, M; Yang, L; Yen, HC	1
Iurasov, VV; Kryzhanovskiĭ, GN; Kucherianu, VG; Kudrin, VS; Nikushkin, EV; Zhigal'tsev, IV	1
Guan, HJ; Ji, XQ; Wang, RG; Wu, WR; Zhu, XZ	1
Beauvillain, J; Benaissa, M; Dexter, D; Fillebeen, C; Mitchell, V; Pierce, A; Spik, G	1
Earl, CD; Ferger, B; Kuschinsky, K; Oertel, WH; Teismann, P	1
Donovan, DM; Kirstein, CL; Kostic, V; Miner, LL; Perry, MP; Philpot, RM; Przedborski, S; Revay, RS; Rothman, RB; Schindler, CW; Sharpe, LG; Uhl, GR	1
Castagnoli, K; Castagnoli, N; Palmer, S	1
Andersen, JK; Andreassen, OA; Beal, MF; Bogdanov, M; Dedeoglu, A; Ferrante, RJ; Jiang, D; Klivenyi, P; Lancelot, E; Mueller, G	1
Grünblatt, E; Mandel, S; Youdim, MB	1
Jackson, M; Jenner, P; Treseder, SA	1
Bing, G; Jhoo, W; Kim, H; Shin, E	1
Mohanakumar, KP; Muralikrishnan, D; Thomas, B	1
Andreassen, OA; Beal, MF; Ferrante, RJ; Klivenyi, P; Lancelot, E; Reif, D	1
Di Monte, DA; Langston, JW; Thiffault, C	2
Albers, DW; Andreassen, OA; Beal, MF; Carlson, EJ; Dedeoglu, A; Epstein, CJ; Ferrante, RJ; Klivenyi, P	1
Auburger, GW; Hofele, K; Huston, JP; Morgan, S; Schwarting, RK; Sedelis, M	1
Araki, T; Ido, T; Imai, Y; Itoyama, Y; Kumagai, T; Matsubara, M	1
Hadjiconstantinou, M; Neff, NH; Wemlinger, TA	1
Albers, DS; Andreassen, OA; Beal, MF; Dedeoglu, A; Ferrante, RJ; Klein, AM; Klivenyi, P; Kowall, NW	1
Beilstein, M; Castagnoli, K; Castagnoli, N; Chen, JF; Petzer, JP; Schwarzschild, MA; Sonsalla, PK; Staal, R; Xu, K; Xu, YH	1
Haass, C; Haid, S; Kahle, PJ; Neumann, M; Okochi, M; Ozmen, L; Rathke-Hartlieb, S; Schulz, JB	1
Abe, K; Miyatake, T; Ren, J; Sano, T; Shinohara, T; Taguchi, K; Utsunomiya, I; Wasai, T	1
Bezard, E; Bioulac, B; Brotchie, JM; Chalon, S; Crossman, AR; Dovero, S; Gross, CE; Guilloteau, D; Prunier, C; Ravenscroft, P	1
Araki, T; Imai, Y; Matsubara, M; Muramatsu, Y; Tanaka, K	1
Araki, T; Imai, Y; Itoyama, Y; Kato, H; Kumagai, T; Matsubara, M; Tanaka, K	1
Lau, YS; Mao, L; Petroske, E; Wang, JQ	1
Morgan, WW; Nelson, JF	1
Barja, G; Fabre, E; Gredilla, R; Leret, ML; San Millán, JA	1
Breidert, T; Callebert, J; Heneka, MT; Hirsch, EC; Landreth, G; Launay, JM	1
Araki, T; Imai, Y; Itoyama, Y; Kato, H; Kurosaki, R; Matsubara, M; Michimata, M; Mikami, T; Muramatsu, Y	1
Cho, MH; Choi, JY; Chung, WG; Jin, BK; Kim, DJ; Park, CS; Pie, JE	1
Araki, T; Imai, Y; Itoyama, Y; Kato, H; Kurosaki, R; Matsubara, M; Michimata, M; Muramatsu, Y	1
Callier, S; D'Astous, M; Di Paolo, T; Morissette, M; Tanguay, B	1
Geldenhuys, WJ; Malan, SF; Terre'Blanche, G; Van der Schyf, CJ	1
Andersen, JK; Beal, MF; Boonplueang, R; Bush, AI; Cherny, RA; DiMonte, D; Ellerby, L; Jacobs, R; Kaur, D; Kumar, J; Mo, JQ; Rajagopalan, S; Viswanath, V; Volitaskis, I; Yang, L; Yantiri, F	1
Bonuccelli, U; Corsini, GU; Maggio, R; Pardini, C; Vaglini, F	1
Battaglia, G; Busceti, CL; De Blasi, A; Fornai, F; Lembo, G; Nicoletti, F	1
Battaglia, G; Biagioni, F; Bruno, V; Busceti, CL; Fornai, F; Molinaro, G; Nicoletti, F; Storto, M	1
Behrouz, B; Drolet, RE; Goudreau, JL; Lookingland, KJ	1
Feldon, J; Ferger, B; Hengerer, B; Leng, A; Mura, A	1
Feldon, J; Ferger, B; Leng, A; Yee, BK	1
Bartoli, C; Corsini, GU; Dinucci, D; Pardini, C; Vaglini, F; Viaggi, C	1
Ali, SF; Cawthon, D; McCastlain, KA; Slikker, W; Xu, Z	1
Araki, T; Imai, Y; Itoyama, Y; Kato, H; Kurosaki, R; Muramatsu, Y; Watanabe, Y	1
Hebert, G; Li, KS; Lin, LY; Luo, YL; Moze, E; Neveu, PJ; Shen, YQ	1
Mitsumoto, Y; Mori, A; Moriizumi, T; Nakai, M; Ohashi, S	1
Selley, ML	1
Dawson, TM; Dawson, VL; Mandir, AS; Shimoji, M; Zhang, L	1
Hebert, G; Li, KS; Moze, E; Neveu, PJ; Shen, YQ; Su, Y	1
Lau, YS; Novikova, L; Roels, C	1
Beal, MF; Browne, SE; Calingasan, NY; Gardian, G; Klivenyi, P; Saydoff, J; von Borstel, R; Yang, L	1
Araki, T; Himeda, T; Kadoguchi, N; Kamiyama, Y; Kato, H; Maegawa, H	1
Miller, DB; O'Callaghan, JP; Sriram, K	1
Castellanos, FX; Gash, CR; Gerhardt, GA; Glaser, PE; Grondin, R; Palmer, M; Surgener, SP	1
Fujimoto, Y; Hara, H; Ito, Y; Kitaichi, K; Nagai, H; Nakayama, H; Oida, Y; Shimazawa, M	1
Bach, A; Bähr, M; Dietz, GP; Ferger, B; Göricke, B; Kobayashi, K; Krüger, C; Laage, R; Lingor, P; Meuer, K; Peters, K; Pitzer, C; Schäbitz, WR; Schlachetzki, JC; Schneider, A; Schulz, JB; Teismann, P; Weber, D; Weishaupt, JH	1
Ali, SF; Charlton, CG; Jiao, Y; Lamango, NS; Lee, ES; Oriaku, ET; Schmued, L; Shepherd, KR; Soliman, KF	1
Cavada, C; Close, RM; Cuadrado, A; de Sagarra, MR; Fernández-Ruiz, J; Jackson-Lewis, V; Montero, C; Rojo, AI; Salazar, M; Sánchez-González, MA	1
Jackson-Lewis, V; Przedborski, S	1
Hirata, Y; Hishida, R; Muramatsu, S; Nagatsu, T; Nakano, I; Ono, K; Sawada, H; Sawada, M; Suzuki, H	1
Cavada, C; Cuadrado, A; de Sagarra, MR; Rojo, AI	1
Aosaki, T; Fuwa, T; Honda, Y; Hua-Qin, W; Ikeda, T; Imai, Y; Inoue, H; Ito, S; Itohara, S; Kaneko, S; Kataoka, A; Kodama, T; Masuda, M; Matsumoto, S; Miura, M; Soda, M; Takahashi, R; Tsukita, K; Wakamatsu, K	1
Chen, WF; Liu, LX; Wong, MS; Xie, JX	1
Araki, T; Kato, H; Takagi, S; Watanabe, Y; Yokoyama, H	1
Rajeswari, A; Sabesan, M	1
Bi, J; Jiang, B; Zhang, H; Zhang, XL	1
Araki, T; Kadoguchi, N; Kato, H; Kimoto, H; Yano, R	1
Minematsu, M; Nakajima, K	1
Guo, Q; Li, S; Liang, Y; Su, B; Wen, C; Zhang, Y	1
Choudhury, ME; Kubo, M; Nagai, M; Nishikawa, N; Nomoto, M; Yabe, H	1
Andersen, ML; Barnabé, GF; Dombrowski, PA; Lima, MM; Reksidler, AB; Tufik, S; Vital, MA	1
Araki, T; Kato, H; Kimoto, H; Kuroiwa, H; Yokoyama, H	1
Borah, A; Mohanakumar, KP	1
Charlton, CG; King, J; Mackey, V; Muthian, G	1
Cantor, CR; Chou, VP; Langston, JW; Manning-Boğ, AB; Molinari, RJ; Pollock, E; Shchepinov, MS	1
Bousquet, M; Calon, F; Cicchetti, F; Drouin-Ouellet, J; Gibrat, C; Kriz, J	1
Bähr, M; Desel, H; Falkenburger, BH; Frank, T; Göricke, B; Klinker, F; Laage, R; Liebetanz, D; Lühder, F; Neurath, H; Schneider, A; Weishaupt, JH	1
Boussicault, L; Callebert, J; Cohen-Salmon, C; Friguet, B; Golmard, JL; Hild, A; Hirsch, EC; Launay, JM; Mariani, J; Petropoulos, I; Prigent, A; Rousselet, E; Schumm, S; Sebban, C	1
Choi, DK; Kim, IS; Kwon, SJ; Myung, SW; Park, JY; Yoon, SH	1
Beck, M; Botham, PA; Breckenridge, CB; Butt, M; Cook, AR; Mathews, JM; Minnema, D; Smith, LL; Sturgess, NC; Tisdel, MO; Travis, KZ; Wolf, JC; Zadory, D	1
Amini, M; Anisman, H; Callaghan, S; Kulczycki, J; Mao, Z; Mount, MP; Park, DS; Slack, RS; Zhang, Y	1
Nakayama, H; Sai, T; Uchida, K	1
Inmozhi Sivakamasundari, R; Rekha, KR; Santha, K; Selvakumar, GP	1
Bao, XQ; Sun, H; Wei, HL; Yu, LH; Zhang, D	1
Ferger, B; Lechel, A; Oeckl, P; Rudolph, KL; Scheffold, A	1
Klivényi, P; Plangár, I; Szalárdy, L; Vécsei, L; Zádori, D	1
Bao, Q; Feng, G; Jiang, J; Li, S; Zhang, Z; Zhou, L	1
Kolacheva, AA; Kozina, EA; Ugryumov, MV; Volina, EV	1
Di Paolo, T; Grégoire, L; Morin, N; Morissette, M	1
Kong, L; Li, M; Liu, Q; Lu, Z; Wang, J; Wei, D; Yang, M	1
Bentea, E; Churchill, MJ; Massie, A; Meshul, CK; Sato, H; Sconce, MD; Van Liefferinge, J	1
Pu, XP; Wang, YH; Zhai, SY; Zhang, HN; Zhou, JJ	1
Aguiar, AS; da Cunha, C; de Oliveira, G; Lopes, SC; Prediger, RD; Raisman-Vozari, R; Rial, D; Tristão, FS	1
Forrester, JV; Martin, HL; Mustafa, S; Riedel, G; Santoro, M; Teismann, P	1
Rai, SN; Singh, D; Singh, SP; Yadav, SK	1
Empl, L; Hain, EG; Iggena, D; Klein, C; Poshtiban, A; Rasińska, J; Rivalan, M; Sparenberg, M; Steiner, B; Winter, Y	1
Alam, G; Jones, BC; Lu, L; Miller, DB; O'Callaghan, JP; Williams, RW	1
Klivenyi, P; Molnar, MF; Salamon, A; Sumegi, E; Torok, R; Vecsei, L; Veres, G; Zadori, D	1
Aymerich, MS; Celorrio, M; Estella-Hermoso de Mendoza, A; Fernández-Suárez, D; Franco, R; Müller, CE; Oyarzábal, J; Ramírez, MJ; Rojo-Bustamante, E; Sáez, E	1
Guo, Y; Jiang, F; Lou, H; Qin, Y; Ren, M; Wei, X; Yan, S; Zhang, X	1
Aguilera, J; Gil, C; Herrando-Grabulosa, M; Limón, DI; Mendieta, L; Moreno-Galarza, N; Palafox-Sánchez, V	1
Joniec-Maciejak, I; Maciejak, P; Mirowska-Guzel, D; Płaźnik, A; Sobolewska, A; Szyndler, J; Turzyńska, D; Wawer, A	1

Reviews

1 review(s) available for 3,4-dihydroxyphenylacetic acid and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

Article	Year
Desferrioxamine and vitamin E protect against iron and MPTP-induced neurodegeneration in mice. Journal of neural transmission (Vienna, Austria : 1996), 1997, Volume: 104, Issue:4-5 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Diseases; Corpus Striatum; Deferoxamine; Dopamine; Female; Glutathione; Glutathione Disulfide; Hydroxyl Radical; Iron; Lipid Peroxides; Male; Mice; Nerve Degeneration; Osmolar Concentration; Vitamin E	1997

Article

Year

Desferrioxamine and vitamin E protect against iron and MPTP-induced neurodegeneration in mice.

Journal of neural transmission (Vienna, Austria : 1996), 1997, Volume: 104, Issue:4-5

Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Diseases; Corpus Striatum; Deferoxamine; Dopamine; Female; Glutathione; Glutathione Disulfide; Hydroxyl Radical; Iron; Lipid Peroxides; Male; Mice; Nerve Degeneration; Osmolar Concentration; Vitamin E

1997

Other Studies

241 other study(ies) available for 3,4-dihydroxyphenylacetic acid and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

Article	Year
Therapy of Morbus Parkinson and radical-induced neurotoxicity in the rat--in vivo voltammetric studies. Journal of neural transmission. Supplementum, 1992, Volume: 38 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Antiparkinson Agents; Apomorphine; Corpus Striatum; Dopamine; Electrochemistry; Free Radicals; Haloperidol; Hydroxyindoleacetic Acid; Male; Memantine; Neurotoxins; Parkinson Disease; Rats; Rats, Wistar; Rotenone; Serotonin; Substantia Nigra	1992
Recovery from experimental parkinsonism in primates with GM1 ganglioside treatment. Science (New York, N.Y.), 1992, May-08, Volume: 256, Issue:5058 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; G(M1) Ganglioside; Homovanillic Acid; Immunohistochemistry; Macaca fascicularis; Motor Activity; Parkinson Disease, Secondary; Putamen; Reference Values; Saimiri; Tyrosine 3-Monooxygenase	1992
Neurotoxic effect of prenatal exposure to MPTP on the dopaminergic systems of the marmoset brain. European journal of pharmacology, 1992, Jul-07, Volume: 217, Issue:2-3 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Adolescent; Animals; Callithrix; Corpus Striatum; Dopamine; Female; Homovanillic Acid; Humans; Nucleus Accumbens; Pregnancy; Prenatal Exposure Delayed Effects	1992
Partial protective effect of MK-801 on MPTP-induced reduction of striatal dopamine in mice. Neuroscience letters, 1992, Jul-20, Volume: 141, Issue:2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Corpus Striatum; Dizocilpine Maleate; Dopamine; Female; Homovanillic Acid; Mice; Mice, Inbred C57BL; Monoamine Oxidase	1992
Effects of age on GM1 ganglioside-induced recovery of concentrations of dopamine in the striatum in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice. Neuropharmacology, 1992, Volume: 31, Issue:2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Corpus Striatum; Dopamine; G(M1) Ganglioside; Male; Mice; Mice, Inbred C57BL	1992
Trace dosages of the neurotoxins MPTP and MPP+ may affect brain dopamine in vivo. Life sciences, 1992, Volume: 51, Issue:5 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Dopamine; Male; Mice; Mice, Inbred C57BL; Reserpine	1992
Epidermal growth factor enhances striatal dopaminergic parameters in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mouse. Journal of neurochemistry, 1991, Volume: 57, Issue:2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Cells, Cultured; Cerebral Ventricles; Corpus Striatum; Dopamine; Embryo, Mammalian; Epidermal Growth Factor; Infusions, Parenteral; Male; Mesencephalon; Mice; Reference Values; Tyrosine 3-Monooxygenase	1991
Prolonged alterations in canine striatal dopamine metabolism following subtoxic doses of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and 4'-amino-MPTP are linked to the persistence of pyridinium metabolites. Journal of neurochemistry, 1991, Volume: 57, Issue:3 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dogs; Dopamine; Dose-Response Relationship, Drug; Homovanillic Acid; Male; Pyridinium Compounds; Tyrosine 3-Monooxygenase	1991
Investigation of the possible dopaminergic toxicity of 1-methyl-3-phenyl-1,2,3,6-tetrahydropyridine, an isomer to the neurotoxin MPTP. Pharmacology & toxicology, 1991, Volume: 69, Issue:1 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Catecholamines; Corpus Striatum; Dopamine; Dopamine Agents; Homovanillic Acid; In Vitro Techniques; Isomerism; Limbic System; Magnetic Resonance Spectroscopy; Male; Mice; Mitochondria, Liver; Monoamine Oxidase; MPTP Poisoning; Rats; Rats, Inbred Strains	1991
In vivo changes of catecholamines in hemiparkinsonian monkeys measured by microdialysis. Experimental neurology, 1990, Volume: 110, Issue:2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Catecholamines; Caudate Nucleus; Dialysis; Dopamine; Female; Homovanillic Acid; Hydroxyindoleacetic Acid; Macaca mulatta; Male; Parkinson Disease, Secondary; Putamen	1990
Transplacentally-transported 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) affects the catecholamine and indoleamine levels in the fetal mouse brain. Journal of neural transmission. Parkinson's disease and dementia section, 1990, Volume: 2, Issue:4 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Brain Chemistry; Dopamine; Female; Hydroxyindoleacetic Acid; Maternal-Fetal Exchange; Mice; Mice, Inbred C57BL; Pregnancy; Serotonin	1990
Effects of L-deprenyl and amantadine in an MPTP-model of parkinsonism. Journal of neural transmission. Supplementum, 1990, Volume: 32 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Amantadine; Animals; Caudate Nucleus; Corpus Striatum; Dopamine; Drug Interactions; Female; Gerbillinae; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Parkinson Disease, Secondary; Selegiline; Serotonin	1990
Neurochemical and behavioural features induced by chronic low dose treatment with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the common marmoset: implications for Parkinson's disease? Neuroscience letters, 1991, Feb-11, Volume: 123, Issue:1 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Amines; Brain; Callitrichinae; Corpus Striatum; Disease Models, Animal; Dopamine; Drug Administration Schedule; Female; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Motor Activity; MPTP Poisoning; Norepinephrine; Parkinson Disease; Posture; Serotonin; Substantia Nigra	1991
The acute convulsant effect of MPTP is dependent on intracerebral MPP+. Neuroscience letters, 1991, Mar-11, Volume: 124, Issue:1 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Convulsants; Corpus Striatum; Ditiocarb; Drug Interactions; Epilepsy; Hippocampus; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Mice; Mice, Inbred C57BL; Monoamine Oxidase Inhibitors; MPTP Poisoning; Status Epilepticus; Stereotyped Behavior	1991
Neuropeptide levels in the basal ganglia of aged common marmosets following prolonged treatment with MPTP. Journal of neural transmission. Parkinson's disease and dementia section, 1991, Volume: 3, Issue:2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Basal Ganglia; Biogenic Monoamines; Callithrix; Caudate Nucleus; Dopamine; Enkephalin, Leucine; Enkephalin, Methionine; Female; Globus Pallidus; Homovanillic Acid; Male; Neuropeptides; Neurotensin; Putamen; Reference Values; Sincalide; Substance P	1991
Extensive loss of brain dopamine and serotonin induced by chronic administration of MPTP in the marmoset. Brain research, 1991, Dec-13, Volume: 567, Issue:1 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Callithrix; Dopamine; Drug Administration Schedule; Female; Homovanillic Acid; Male; MPTP Poisoning; Organ Specificity; Reference Values; Serotonin	1991
6-[18F]fluoro-L-dopa metabolism in MPTP-treated monkeys: assessment of tracer methodologies for positron emission tomography. Brain research, 1991, Mar-15, Volume: 543, Issue:2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Dopamine; Female; Homovanillic Acid; Macaca nemestrina; Male; Tomography, Emission-Computed	1991
Levels of pros-methylimidazoleacetic acid: correlation with severity of Parkinson's disease in CSF of patients and with the depletion of striatal dopamine and its metabolites in MPTP-treated mice. Journal of neural transmission. Parkinson's disease and dementia section, 1991, Volume: 3, Issue:2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Aged; Animals; Cerebral Cortex; Corpus Striatum; Dopamine; Female; Homovanillic Acid; Humans; Imidazoles; Male; Mice; Mice, Inbred C57BL; Norepinephrine; Parkinson Disease; Reference Values	1991
Basic FGF reverses chemical and morphological deficits in the nigrostriatal system of MPTP-treated mice. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1990, Volume: 10, Issue:6 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Fibroblast Growth Factors; Immunoblotting; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Nerve Growth Factors; Nerve Tissue Proteins; Substantia Nigra; Tyrosine 3-Monooxygenase	1990
Long-term effect of MPTP in the mouse brain in relation to aging: neurochemical and immunocytochemical analysis. Brain research, 1990, Jun-11, Volume: 519, Issue:1-2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Brain; Disease Models, Animal; Dopamine; Histocytochemistry; Homovanillic Acid; Male; Mice; Mice, Inbred C57BL; Norepinephrine; Parkinson Disease; Reference Values; Serotonin; Tyrosine 3-Monooxygenase	1990
The evolution of nigrostriatal neurochemical changes in the MPTP-treated squirrel monkey. Brain research, 1990, Oct-29, Volume: 531, Issue:1-2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Caudate Nucleus; Dopamine; Homovanillic Acid; Male; Monoamine Oxidase; Motor Activity; Putamen; Reference Values; Saimiri; Substantia Nigra; Tyrosine 3-Monooxygenase	1990
Depletion of cardiac norepinephrine but not brain catecholamines by MPTP-N-oxide in mice. Life sciences, 1990, Volume: 47, Issue:9 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Catecholamines; Cyclic N-Oxides; Dopamine; Heart; Homovanillic Acid; Male; Mice; Mice, Inbred Strains; Myocardium; Norepinephrine; Organ Specificity; Reference Values	1990
GM1 gangliosides alter acute MPTP-induced behavioral and neurochemical toxicity in mice. Journal of the neurological sciences, 1990, Volume: 99, Issue:1 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Corpus Striatum; Dopamine; G(M1) Ganglioside; Homovanillic Acid; Male; Mice; Mice, Inbred Strains; Movement; Parkinson Disease; Parkinson Disease, Secondary	1990
Effects of chronic treatment of MPTP monkeys with bromocriptine alone or in combination with SKF 38393. European journal of pharmacology, 1990, Aug-28, Volume: 185, Issue:2-3 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 3,4-Dihydroxyphenylacetic Acid; Animals; Antiparkinson Agents; Brain; Brain Chemistry; Bromocriptine; Dopamine; Female; Homovanillic Acid; Kinetics; Levodopa; Macaca fascicularis; Motor Activity; MPTP Poisoning; Parkinson Disease, Secondary; Receptors, Dopamine; Spiperone	1990
Prolonged changes in plasma concentrations of catecholamine metabolites following a single infusion of an MPTP analog. Life sciences, 1990, Volume: 47, Issue:21 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Adrenal Glands; Animals; Catecholamines; Dogs; Female; Injections, Intravenous; Male; Methoxyhydroxyphenylglycol; Normetanephrine; Sympathetic Nervous System; Time Factors	1990
Attenuation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity by tobacco smoke. Neuropharmacology, 1990, Volume: 29, Issue:3 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Homovanillic Acid; Liver; Male; Mice; Mice, Inbred C57BL; Monoamine Oxidase; MPTP Poisoning; Nervous System Diseases; Smoking	1990
Dopamine receptor plasticity following MPTP-induced nigrostriatal lesions in the mouse. European journal of pharmacology, 1990, May-16, Volume: 180, Issue:2-3 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; In Vitro Techniques; Kinetics; Male; Mice; Receptors, Dopamine; Spiperone; Substantia Nigra; Up-Regulation	1990
The protective effect of 1-tert.butyl-4,4-diphenylpiperidine against the nigrostriatal neurodegeneration caused by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Life sciences, 1985, Sep-30, Volume: 37, Issue:13 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Dopamine; Drug Interactions; Female; Homovanillic Acid; Hydroxyindoleacetic Acid; Piperidines; Pyridines; Rats; Rats, Inbred Strains; Serotonin	1985
The toxic actions of MPTP and its metabolite MPP+ are not mimicked by analogues of MPTP lacking an N-methyl moiety. Neuroscience letters, 1985, Oct-24, Volume: 61, Issue:1-2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Diseases; Chemical Phenomena; Chemistry; Corpus Striatum; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Movement Disorders; Norepinephrine; Pyridines; Pyridinium Compounds; Rats; Serotonin; Substantia Nigra	1985
Comparison of 1-methyl-4-(p-chlorophenyl)-1,2,3,6-tetrahydropyridine, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and p-chloroamphetamine as monoamine depletors. Research communications in chemical pathology and pharmacology, 1985, Volume: 50, Issue:1 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Amphetamines; Animals; Biogenic Amines; Brain Chemistry; Corpus Striatum; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; p-Chloroamphetamine; Pyridines; Rats; Rats, Inbred Strains; Serotonin; Time Factors	1985
The neurotoxic actions of 6-hydroxydopamine infused into the rat substantia nigra. Neuroscience letters, 1986, Jun-18, Volume: 67, Issue:2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Homovanillic Acid; Hydroxydopamines; Hydroxyindoleacetic Acid; Male; Movement Disorders; Neurotransmitter Agents; Oxidopamine; Pyridines; Pyridinium Compounds; Rats; Rats, Inbred Strains; Substantia Nigra	1986
Long-term effects of MPTP on central and peripheral catecholamine and indoleamine concentrations in monkeys. Brain research, 1986, Aug-06, Volume: 379, Issue:2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Amines; Brain; Bromocriptine; Catecholamines; Chromatography, High Pressure Liquid; Female; Homovanillic Acid; Hydroxyindoleacetic Acid; Levodopa; Macaca fascicularis; Parkinson Disease, Secondary; Prolactin; Pyridines	1986
Lack of change in basal ganglia neuropeptide content following subacute 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine treatment of the common marmoset. Journal of neurochemistry, 1986, Volume: 47, Issue:5 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Basal Ganglia; Behavior, Animal; Callitrichinae; Caudate Nucleus; Enkephalin, Leucine; Enkephalin, Methionine; Female; Homovanillic Acid; Male; Neuropeptides; Putamen; Pyridines; Sincalide; Substance P	1986
Effect of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on levels of glutathione in the extrapyramidal system of the mouse. Neuropharmacology, 1986, Volume: 25, Issue:9 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Extrapyramidal Tracts; Glutathione; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Mice; Pyridines; Substantia Nigra	1986
The development of amine substituted analogues of MPTP as unique tools for the study of MPTP toxicity and Parkinson's disease. Life sciences, 1987, Feb-23, Volume: 40, Issue:8 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Amines; Animals; Brain Chemistry; Corpus Striatum; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Immunologic Techniques; Male; Mice; Pargyline; Parkinson Disease, Secondary; Pyridines; Serotonin; Structure-Activity Relationship	1987
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxicity in mice is enhanced by ethanol or acetaldehyde. Life sciences, 1987, Mar-02, Volume: 40, Issue:9 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Acetaldehyde; Animals; Brain; Dopamine; Drug Synergism; Ethanol; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Mice; Mice, Inbred C57BL; Neurotoxins; Pyridines; Serotonin	1987
Neurochemical changes in the substantiae nigrae and caudate nuclei following acute unilateral intranigral infusions of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Brain research, 1986, Dec-10, Volume: 399, Issue:2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Catecholamines; Caudate Nucleus; Dopamine; Female; Homovanillic Acid; Hydroxyindoleacetic Acid; Methoxyhydroxyphenylglycol; Motor Activity; Norepinephrine; Pyridines; Rats; Rats, Inbred Strains; Serotonin; Substantia Nigra	1986
Behavioral and biochemical changes following acute administration of MPTP and MPP+. Life sciences, 1987, Mar-30, Volume: 40, Issue:13 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Desipramine; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Mice; Motor Activity; Nomifensine; Pyridines; Pyridinium Compounds; Selegiline; Serotonin	1987
On the mechanisms underlying 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity: the effect of perinigral infusion of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, its metabolite and their analogs in the rat. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 241, Issue:2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Histocytochemistry; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Neurons; Pyridines; Pyridinium Compounds; Rats; Rats, Inbred Strains; Serotonin; Substantia Nigra	1987
Partial protection from the dopaminergic neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) by Pro-Leu-Gly-NH2(PLG; MIF-1). Life sciences, 1987, May-18, Volume: 40, Issue:20 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Basal Ganglia Diseases; Corpus Striatum; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Mice; Mice, Inbred C57BL; MSH Release-Inhibiting Hormone; Norepinephrine; Pyridines; Serotonin; Substantia Nigra	1987
Levels of Met-enkephalin, Leu-enkephalin, substance P and cholecystokinin in the brain of the common marmoset following long term 1-methyl-4-phenyl-1,2,3,6,-tetrahydropyridine treatment. Neuropeptides, 1988, Volume: 12, Issue:3 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Callitrichinae; Cholecystokinin; Dopamine; Enkephalin, Leucine; Enkephalin, Methionine; Female; Homovanillic Acid; Male; Organ Specificity; Pyridines; Reference Values; Substance P	1988
Chronic L-deprenyl does not alter the restoration of striatal dopamine in MPTP-lesioned mice. Journal of neuroscience research, 1989, Volume: 23, Issue:3 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Male; Mice; Mice, Inbred BALB C; Parkinson Disease, Secondary; Phenethylamines; Pyridines; Selegiline; Time Factors	1989
Increased caudate dopamine turnover may contribute to the recovery of motor function in marmosets treated with the dopaminergic neurotoxin MPTP. Neuroscience letters, 1989, Jul-03, Volume: 101, Issue:3 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Callitrichinae; Caudate Nucleus; Dopamine; Homovanillic Acid; Male; Neurotoxins; Parkinson Disease, Secondary; Pyridines; Time Factors	1989
Further treatment with MPTP does not produce parkinsonism in marmosets showing behavioural recovery from motor deficits induced by an earlier exposure to the toxin. Neuropharmacology, 1989, Volume: 28, Issue:10 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Autoradiography; Brain; Brain Chemistry; Callitrichinae; Dopamine; Female; Homovanillic Acid; Male; Parkinson Disease, Secondary; Psychomotor Performance	1989
Treatment with a selective MAO B inhibitor prevents loss of dopamine in the nucleus accumbens of MPTP-treated common marmosets. Neuropharmacology, 1989, Volume: 28, Issue:11 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Allylamine; Animals; Behavior, Animal; Biogenic Amines; Callitrichinae; Caudate Nucleus; Dopamine; Female; Homovanillic Acid; Male; Monoamine Oxidase Inhibitors; Nucleus Accumbens; Parkinson Disease, Secondary; Putamen; Septal Nuclei	1989
Sodium diethyldithiocarbamate protects against the MPTP-induced inhibition of immune responses in mice. Life sciences, 1989, Volume: 44, Issue:12 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; B-Lymphocytes; Corpus Striatum; Designer Drugs; Ditiocarb; Dopamine; Homovanillic Acid; Immune System; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Male; Metallothionein 3; Mice; Mitogens; Pyridines; Selegiline; T-Lymphocytes	1989
GM1 ganglioside-induced recovery of nigrostriatal dopaminergic neurons after MPTP: an immunohistochemical study. Brain research, 1989, Apr-10, Volume: 484, Issue:1-2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; G(M1) Ganglioside; Immunohistochemistry; Male; Mice; Parkinson Disease, Secondary; Pyridines; Substantia Nigra; Tyrosine 3-Monooxygenase	1989
Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in the dog: effect of pargyline pretreatment. Journal of neurochemistry, 1989, Volume: 53, Issue:2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Brain; Dogs; Dopamine; Female; Male; Monoamine Oxidase; Norepinephrine; Pargyline; Pyridines; Tissue Distribution; Tyrosine 3-Monooxygenase	1989
A high dose of MPTP overcomes the protective effect of selegiline against dopaminergic neurotoxicity. The Journal of pharmacy and pharmacology, 1989, Volume: 41, Issue:7 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Homovanillic Acid; Male; Mice; Mice, Inbred Strains; Nervous System Diseases; Phenethylamines; Pyridines; Receptors, Dopamine; Selegiline	1989
Morphological, neurochemical, and behavioral characterizations associated with the combined treatment of diethyldithiocarbamate and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice. Brain research, 1989, Sep-18, Volume: 497, Issue:2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Brain; Circadian Rhythm; Ditiocarb; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Immunoenzyme Techniques; Male; Mice; Mice, Inbred C57BL; Motor Activity; Reference Values; Stereotyped Behavior; Tyrosine 3-Monooxygenase	1989
The influence of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine on the levels of dopamine, serotonin and their metabolites in the caudate nucleus of the rat. Arzneimittel-Forschung, 1985, Volume: 35, Issue:2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Caudate Nucleus; Disease Models, Animal; Dopamine; Female; Homovanillic Acid; Hydroxyindoleacetic Acid; Parkinson Disease, Secondary; Pyridines; Rats; Rats, Inbred Strains; Serotonin	1985
Beta-carboline analogues of N-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP): endogenous factors underlying idiopathic parkinsonism? Neuroscience letters, 1985, Apr-09, Volume: 55, Issue:2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Aotus trivirgatus; Carbolines; Caudate Nucleus; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Indoles; Parkinson Disease; Parkinson Disease, Secondary; Pyridines; Serotonin; Substantia Nigra	1985
Dissociation between biochemical and behavioral recovery in MPTP-treated mice. Pharmacology, biochemistry, and behavior, 1989, Volume: 34, Issue:1 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Benzazepines; Corpus Striatum; Dopamine; Dopamine Antagonists; Drug Interactions; Haloperidol; Male; Mice; Phenylacetates; Psychomotor Performance; Sulpiride; Time Factors	1989
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) does not destroy nigrostriatal neurons in the scorbutic guinea pig. Life sciences, 1985, Apr-01, Volume: 36, Issue:13 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Ascorbic Acid Deficiency; Brain; Choline O-Acetyltransferase; Corpus Striatum; Disease Models, Animal; Dopamine; Guinea Pigs; Homovanillic Acid; Male; Neurons; Pyridines; Tyrosine 3-Monooxygenase	1985
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) administration to C57-black mice leads to parallel decrements in neostriatal dopamine content and tyrosine hydroxylase activity. European journal of pharmacology, 1986, Jan-29, Volume: 120, Issue:3 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Homovanillic Acid; Male; Mice; Mice, Inbred C57BL; Pyridines; Tyrosine 3-Monooxygenase	1986
Effect of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on striatal tyrosine hydroxylase and tryptophan hydroxylase in rat. Neuropharmacology, 1986, Volume: 25, Issue:3 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Haloperidol; Homovanillic Acid; Kinetics; Male; Neurotoxins; Pyridines; Rats; Rats, Inbred Strains; Tryptophan Hydroxylase; Tyrosine 3-Monooxygenase	1986
Persistent depletion of striatal dopamine and its metabolites in mice by TMMP, an analogue of MPTP. The Journal of pharmacy and pharmacology, 1987, Volume: 39, Issue:8 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Homovanillic Acid; Male; Mice; Mice, Inbred Strains; Oxidation-Reduction; Pyridines	1987
Immunohistochemical evaluation of the neurotoxic effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on dopaminergic nigrostriatal neurons of young adult mice using dopamine and tyrosine hydroxylase antibodies. Neuroscience letters, 1988, Jul-19, Volume: 90, Issue:1-2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Nerve Regeneration; Neurotoxins; Pyridines; Substantia Nigra; Time Factors; Tyrosine 3-Monooxygenase	1988
Relation between brain dopamine loss and D2 dopamine receptor density in MPTP monkeys. Neuroscience letters, 1988, Mar-31, Volume: 86, Issue:2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Female; Homovanillic Acid; Kinetics; Macaca fascicularis; Nucleus Accumbens; Ovariectomy; Pyridines; Receptors, Dopamine; Receptors, Dopamine D2; Septal Nuclei; Spiperone	1988
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxicity in mice is enhanced by pretreatment with diethyldithiocarbamate. European journal of pharmacology, 1985, Dec-10, Volume: 119, Issue:1-2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Amines; Brain; Ditiocarb; Dopamine; Drug Synergism; Dyskinesia, Drug-Induced; Homovanillic Acid; Male; Mice; Mice, Inbred C57BL; Motor Activity; Nervous System Diseases; Posture; Pyridines; Thiocarbamates	1985
Studies on the mechanism of the dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Advances in neurology, 1987, Volume: 45 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Corpus Striatum; Dopamine; Homovanillic Acid; Male; Mice; Mice, Inbred Strains; Pyridines; Pyridinium Compounds; Receptors, Dopamine; Selegiline	1987
Dopamine and norepinephrine in the gastrointestinal tract of mice and the effects of neurotoxins. The Journal of pharmacology and experimental therapeutics, 1988, Volume: 244, Issue:2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Digestive System; Dopamine; Hydroxydopamines; Intestinal Mucosa; Male; Mice; Myenteric Plexus; Neurotoxins; Norepinephrine; Oxidopamine; Pyridines	1988
Suppression of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic neurotoxicity in mouse brain by piroheptine and trihexyphenidyl. Journal of the neurological sciences, 1988, Volume: 83, Issue:2-3 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Clomipramine; Corpus Striatum; Dibenzocycloheptenes; Dopamine; Drug Interactions; Male; Mice; Mice, Inbred C57BL; Parasympatholytics; Parkinson Disease, Secondary; Pyridines; Pyrrolidines; Trihexyphenidyl	1988
Dopamine-releasing action of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and 1-methyl-4-phenylpyridine (MPP+) in the neostriatum of the rat as demonstrated in vivo by the push-pull perfusion technique: dependence on sodium but not calcium ions. Brain research, 1988, Mar-08, Volume: 443, Issue:1-2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Animals; Benztropine; Calcium; Corpus Striatum; Dopamine; Kinetics; Male; Neurotoxins; Ouabain; Perfusion; Pyridines; Pyridinium Compounds; Rats; Rats, Inbred Strains; Reference Values; Sodium	1988
Acute stress or neuroleptics elicit sensorimotor deficits in MPTP-treated mice. Neuroscience letters, 1988, Feb-15, Volume: 85, Issue:1 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Cold Temperature; Corpus Striatum; Dopamine; Haloperidol; Injections, Intraperitoneal; Male; Mice; Psychomotor Disorders; Pyridines; Stress, Physiological	1988
Biochemical aspects of Parkinson-dementia complex. European neurology, 1988, Volume: 28 Suppl 1 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Dementia; Female; Humans; Levodopa; Male; Mice; Middle Aged; Oxygen; Parkinson Disease; Pyridines; Serotonin; Tryptophan Hydroxylase	1988
Possible treatment of Parkinson's disease with intrathecal medication in the MPTP model. Annals of the New York Academy of Sciences, 1988, Volume: 531 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Homovanillic Acid; Infusion Pumps; Injections, Spinal; Levodopa; Parkinson Disease, Secondary; Pyridines; Time Factors	1988
Systemic 1-methyl,4-phenyl,1-2-3-6-tetrahydropyridine (MPTP) administration decreases retinal dopamine content in primates. Life sciences, 1988, Volume: 43, Issue:3 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Chromatography, Liquid; Dopamine; Electroretinography; Evoked Potentials, Visual; Female; Macaca fascicularis; Parkinson Disease, Secondary; Pattern Recognition, Visual; Pyridines; Retina	1988
Behavioral and biochemical effect of chronic treatment with D-1 and/or D-2 dopamine agonists in MPTP monkeys. European journal of pharmacology, 1988, May-20, Volume: 150, Issue:1-2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Benzazepines; Brain Chemistry; Dopamine; Dyskinesia, Drug-Induced; Female; Homovanillic Acid; Macaca fascicularis; Motor Activity; Parkinson Disease, Secondary; Pyridines; Receptors, Dopamine; Spiperone	1988
Treatment with GM1 ganglioside restores striatal dopamine in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mouse. Journal of neurochemistry, 1988, Volume: 51, Issue:4 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; G(M1) Ganglioside; Male; Mice; Pyridines	1988
Characterization of hepatic microsomal metabolism as an in vivo detoxication pathway of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice. The Journal of pharmacology and experimental therapeutics, 1988, Volume: 246, Issue:3 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Cytochrome P-450 Enzyme System; Dopamine; Homovanillic Acid; Inactivation, Metabolic; Male; Methylcholanthrene; Mice; Mice, Inbred C57BL; Microsomes, Liver; Oxygenases; Phenobarbital; Pyridines	1988
Acute effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on catecholamines in heart, adrenal gland, retina and caudate nucleus of the cat. Toxicology letters, 1988, Volume: 44, Issue:1-2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Adrenal Glands; Animals; Catecholamines; Cats; Caudate Nucleus; Dopamine; Epinephrine; Female; Heart; Homovanillic Acid; Male; Myocardium; Norepinephrine; Pyridines; Retina	1988
Increase of striatal dopamine turnover by stress in MPTP-treated mice. Clinical neuropharmacology, 1988, Volume: 11, Issue:4 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Cerebral Cortex; Corpus Striatum; Dopamine; Homovanillic Acid; Male; Mice; Mice, Inbred C57BL; Motor Activity; Pyridines; Reference Values; Restraint, Physical; Stress, Psychological	1988
Effects on dopamine metabolism of MPTP and MPP+ infused through a push-pull cannula into the caudate nucleus of awake adult male rats. Brain research, 1987, Oct-20, Volume: 424, Issue:1 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Animals; Caudate Nucleus; Dopamine; Infusions, Parenteral; Kinetics; Male; Neurotoxins; Pyridines; Pyridinium Compounds; Rats; Rats, Inbred Strains; Stereotaxic Techniques	1987
Persistent depletion of striatal dopamine in mice by 1-methyl-4-(2-thienyl)-1,2,3,6-tetrahydropyridine (MTTP). Biochemical pharmacology, 1986, Jan-15, Volume: 35, Issue:2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Homovanillic Acid; Male; Mice; Neurotoxins; Pyridines; Structure-Activity Relationship	1986
Synthesis and toxicity toward nigrostriatal dopamine neurons of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) analogues. Journal of medicinal chemistry, 1986, Volume: 29, Issue:3 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Homovanillic Acid; Male; Mice; Neurons; Pyridines; Structure-Activity Relationship; Substantia Nigra	1986
The mechanism of action of MPTP and MPP+ on endogenous dopamine release from the rat corpus striatum superfused in vitro. Brain research, 1986, Mar-12, Volume: 368, Issue:1 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Drug Interactions; Male; Perfusion; Potassium; Pyridines; Pyridinium Compounds; Rats; Rats, Inbred Strains	1986
Comparative toxicity of MPTP, MPP+ and 3,3-dimethyl-MPDP+ to dopaminergic neurons of the rat substantia nigra. European journal of pharmacology, 1986, May-13, Volume: 124, Issue:1-2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Animals; Dopamine; Herbicides; Homovanillic Acid; Male; Neurons; Pyridines; Pyridinium Compounds; Rats; Rats, Inbred Strains; Receptors, Dopamine; Substantia Nigra	1986
The catecholamine uptake blocker nomifensine protects against MPTP-induced parkinsonism in monkeys. Experimental brain research, 1986, Volume: 63, Issue:1 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Basal Ganglia; Dopamine; Female; Macaca fascicularis; Male; Nomifensine; Parkinson Disease, Secondary; Pyridines; Substantia Nigra	1986
Characterization of the neurotoxic potential of m-methoxy-MPTP and the use of its N-ethyl analogue as a means of avoiding exposure to a possible Parkinsonism-causing agent. Journal of medicinal chemistry, 1986, Volume: 29, Issue:8 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Corpus Striatum; Dopamine; Homovanillic Acid; Mice; Parkinson Disease, Secondary; Pyridines; Structure-Activity Relationship	1986
Variability and functional recovery in the N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of parkinsonism in monkeys. Neuroscience, 1986, Volume: 18, Issue:4 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Disease Models, Animal; Dopamine; Female; Macaca fascicularis; Male; Monkey Diseases; Parkinson Disease, Secondary; Pyridines; Time Factors	1986
Effect of amphetamine on 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxicity in mice. Neuropharmacology, 1986, Volume: 25, Issue:8 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dextroamphetamine; Dopamine; Drug Interactions; Homovanillic Acid; Mice; Mice, Inbred BALB C; Pyridines	1986
The influence of dose and dosing interval on MPTP-induced dopaminergic neurotoxicity in mice. European journal of pharmacology, 1986, Oct-07, Volume: 129, Issue:3 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Homovanillic Acid; Male; Mice; Mice, Inbred Strains; Pyridines; Species Specificity; Substantia Nigra	1986
Differential responsiveness to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity in sub-regions of the primate substantia nigra and striatum. Life sciences, 1987, Jan-12, Volume: 40, Issue:2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Caudate Nucleus; Chlorocebus aethiops; Corpus Striatum; Dopamine; Homovanillic Acid; Male; Neurotoxins; Norepinephrine; Pyridines; Substantia Nigra	1987
Evaluation of the biological activity of several analogs of the dopaminergic neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Journal of neurochemistry, 1987, Volume: 48, Issue:3 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Corpus Striatum; Dopamine; Homovanillic Acid; Male; Mice; Mice, Inbred C57BL; Mitochondria; Monoamine Oxidase; Nervous System Diseases; Parkinson Disease; Pyridines; Substantia Nigra	1987
Long-term effect of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on striatal dopamine content in young and mature mice. Journal of the neurological sciences, 1987, Volume: 77, Issue:2-3 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Corpus Striatum; Dopamine; Male; Mice; Mice, Inbred C57BL; Pyridines	1987
Tissue culture model for studying MPTP toxicity to dopamine neurons. Advances in neurology, 1987, Volume: 45 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Culture Techniques; Dopamine; Homovanillic Acid; Mesencephalon; Neurons; Pyridines; Pyridinium Compounds; Rats; Receptors, Dopamine	1987
Endogenous analogs of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: indoleamine derived tetrahydro-beta-carbolines as potential causative factors in Parkinson's disease. Advances in neurology, 1987, Volume: 45 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Aotus trivirgatus; Brain; Carbolines; Dopamine; Homovanillic Acid; Mice; Mice, Inbred C57BL; Parkinson Disease, Secondary; Pyridines; Structure-Activity Relationship	1987
Evidence for the involvement of dopamine agonists and antagonists in duodenal ulcer disease. Klinische Wochenschrift, 1986, Volume: 64 Suppl 7 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Brain Chemistry; Cysteamine; Dopamine; Duodenal Ulcer; Gastric Juice; Monoamine Oxidase; Nitriles; Norepinephrine; Pancreatic Juice; Pyridines; Receptors, Dopamine; Secretory Rate; Serotonin; Structure-Activity Relationship	1986
Exposure to cigarette smoke does not decrease the neurotoxicity of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice. Neuroscience letters, 1987, Feb-24, Volume: 74, Issue:2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Disease Susceptibility; Dopamine; Homovanillic Acid; Male; Mice; Mice, Inbred C57BL; Nicotiana; Parkinson Disease, Secondary; Plants, Toxic; Pyridines; Smoke	1987
Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on catecholamines and metabolites in primate brain and CSF. Brain research, 1987, Jul-14, Volume: 415, Issue:2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Catecholamines; Chlorocebus aethiops; Corpus Striatum; Dopamine; Homovanillic Acid; Male; Methoxyhydroxyphenylglycol; Pyridines; Tegmentum Mesencephali	1987
The use of the MPTP-treated mouse as an animal model of parkinsonism. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 1987, Volume: 14, Issue:3 Suppl Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Disease Models, Animal; Dopamine; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Parkinson Disease, Secondary; Pyridines; Species Specificity; Substantia Nigra	1987
Behavioral and biochemical effects of nicotine in an MPTP-induced mouse model of Parkinson's disease. Pharmacology, biochemistry, and behavior, 1987, Volume: 28, Issue:2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Disease Models, Animal; Dopamine; Drug Tolerance; Female; Homovanillic Acid; Mice; Mice, Inbred BALB C; Motor Activity; Nicotine; Olfactory Bulb; Parkinson Disease; Pyridines	1987
Persistent depletion of striatal dopamine in mice by m-hydroxy-MPTP. Research communications in chemical pathology and pharmacology, 1986, Volume: 53, Issue:2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Cerebral Cortex; Corpus Striatum; Dopamine; Homovanillic Acid; Isomerism; Male; Mice; Mice, Inbred Strains; Norepinephrine; Pyridines; Structure-Activity Relationship	1986
Inhibition of types A and B monoamine oxidase by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. The Journal of pharmacology and experimental therapeutics, 1985, Volume: 232, Issue:3 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 2H-Benzo(a)quinolizin-2-ol, 2-Ethyl-1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-; 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Dextroamphetamine; Dogs; Dopamine; Homovanillic Acid; In Vitro Techniques; Kinetics; Liver; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Pargyline; Pyridines; Rats; Rats, Inbred Strains	1985
Influence of selective, reversible inhibitors of monoamine oxidase on the prolonged depletion of striatal dopamine by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice. Life sciences, 1985, Sep-23, Volume: 37, Issue:12 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Alkaloids; Animals; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Harmaline; Homovanillic Acid; Male; Mice; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones; Oxidation-Reduction; Pyridines	1985
Effects of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and its metabolite, N-methyl-4-phenylpyridinium ion, on dopaminergic nigrostriatal neurons in the mouse. Neuroscience letters, 1985, Aug-05, Volume: 58, Issue:3 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Homovanillic Acid; Male; Mice; Mice, Inbred C57BL; Pyridines; Pyridinium Compounds; Substantia Nigra	1985
Electrophysiological and neurochemical correlates of the neurotoxic effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on central catecholamine neurons in the mouse. Naunyn-Schmiedeberg's archives of pharmacology, 1985, Volume: 331, Issue:1 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Action Potentials; Animals; Brain Chemistry; Catecholamines; Dopamine; Male; Mice; Neurons; Norepinephrine; Phencyclidine; Pyridines; Spiperone; Time Factors	1985
Differential neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in Swiss-Webster mice from different sources. European journal of pharmacology, 1985, Oct-29, Volume: 117, Issue:1 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Corpus Striatum; Dopamine; Homovanillic Acid; Male; Mice; Nervous System Diseases; Pyridines; Species Specificity	1985
Dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP) in the mouse: relationships between monoamine oxidase, MPTP metabolism and neurotoxicity. Life sciences, 1985, Jan-21, Volume: 36, Issue:3 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Benzylamines; Clorgyline; Corpus Striatum; Dopamine; Homovanillic Acid; Male; Mice; Mice, Inbred C57BL; Monoamine Oxidase; Pyridines; Selegiline; Substantia Nigra; Synaptosomes; Tryptamines	1985
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine: correspondence of its binding sites to monoamine oxidase in rat brain, and inhibition of dopamine oxidative deamination in vivo and in vitro. Journal of neurochemistry, 1985, Volume: 45, Issue:3 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Binding Sites; Clorgyline; Corpus Striatum; Deamination; Dopamine; In Vitro Techniques; Male; Monoamine Oxidase; Oxidation-Reduction; Pargyline; Pyridines; Rats; Rats, Inbred Strains; Selegiline; Subcellular Fractions	1985
Biochemical and functional evidence for a marked dopamine releasing action of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (NMPTP) in mouse brain. Journal of neural transmission, 1984, Volume: 60, Issue:3-4 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Mice; Motor Activity; Pyridines; Serotonin	1984
Neurochemical and behavioral effects of systemic and intranigral administration of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in the rat. European journal of pharmacology, 1984, Apr-20, Volume: 100, Issue:2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Brain Chemistry; Caudate Nucleus; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Nucleus Accumbens; Pyridines; Raphe Nuclei; Rats; Rats, Inbred Strains; Serotonin; Substantia Nigra	1984
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism in the common marmoset. Neuroscience letters, 1984, Sep-07, Volume: 50, Issue:1-3 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Callitrichinae; Caudate Nucleus; Dopamine; Female; Homovanillic Acid; Levodopa; Parkinson Disease, Secondary; Putamen; Pyridines	1984
Dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine in mice. Science (New York, N.Y.), 1984, Jun-29, Volume: 224, Issue:4656 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Brain Chemistry; Dopamine; Homovanillic Acid; Humans; Male; Mice; Pyridines; Substantia Nigra; Synaptosomes	1984
Repeated administration of N-methyl-4-phenyl 1,2,5,6-tetrahydropyridine to rats is not toxic to striatal dopamine neurones. Biochemical pharmacology, 1984, Jun-01, Volume: 33, Issue:11 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Apomorphine; Corpus Striatum; Dopamine; Homovanillic Acid; Male; Motor Activity; Neurons; Pyridines; Rats; Rats, Inbred Strains	1984
Effects of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine on neostriatal dopamine in mice. Neuropharmacology, 1984, Volume: 23, Issue:6 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Homovanillic Acid; Male; Mice; Mice, Inbred Strains; Pyridines	1984
Effects of deprenyl on monoamine oxidase and neurotransmitters in the brains of MPTP-treated aging mice. Neurochemical research, 1995, Volume: 20, Issue:4 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Brain; Corpus Striatum; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Mice; Mice, Inbred C57BL; Monoamine Oxidase; Neurotransmitter Agents; Olfactory Pathways; Selegiline	1995
Response of the damaged dopamine system to GM1 and semisynthetic gangliosides: effects of dose and extent of lesion. Neuropharmacology, 1995, Volume: 34, Issue:5 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Antiparkinson Agents; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; G(M1) Ganglioside; Gangliosides; Mice; Mice, Inbred C57BL; Sphingosine	1995
Functional studies on monoaminergic transmitter release in parkinsonism. Progress in neuro-psychopharmacology & biological psychiatry, 1993, Volume: 17, Issue:3 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; 5-Hydroxytryptophan; Animals; Apomorphine; Biogenic Monoamines; Dopamine; Dopamine Agents; Dopamine Antagonists; Hydroxyindoleacetic Acid; Levodopa; Male; Monoamine Oxidase Inhibitors; Parkinson Disease, Secondary; Rats; Rats, Wistar; Stereotyped Behavior; Tryptophan	1993
Effects of nimodipine on the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced depletions in the biogenic amine levels in mice. Arzneimittel-Forschung, 1993, Volume: 43, Issue:4 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Amines; Caudate Nucleus; Dopamine; Dopamine Agents; Homovanillic Acid; Hydroxyindoleacetic Acid; Mice; Mice, Inbred C57BL; Nimodipine; Serotonin	1993
Riluzole and experimental parkinsonism: antagonism of MPTP-induced decrease in central dopamine levels in mice. Neuroreport, 1994, Dec-20, Volume: 5, Issue:18 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Dopamine; Homovanillic Acid; Male; Mice; Mice, Inbred C57BL; Monoamine Oxidase Inhibitors; Parkinson Disease, Secondary; Riluzole; Thiazoles	1994
Elevation of neuronal MAO-B activity in a transgenic mouse model does not increase sensitivity to the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Brain research, 1994, Sep-05, Volume: 656, Issue:1 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Animals; Dopamine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Monoamine Oxidase; Neostriatum; Neurons; Substantia Nigra; Tyrosine 3-Monooxygenase	1994
Effects of bifemelane on parkinsonism induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the common marmoset. Neuroscience letters, 1994, Aug-29, Volume: 178, Issue:1 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Antidepressive Agents; Benzhydryl Compounds; Callithrix; Caudate Nucleus; Dopamine; Female; Homovanillic Acid; Male; Microdialysis; Motor Activity; Parkinson Disease, Secondary; Reference Values	1994
Sex-related effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydro-pyridine treatment may be related to differences in monoamine oxidase B. Neuroscience letters, 1994, Aug-01, Volume: 176, Issue:2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Animals; Dopamine; Estrus; Female; Homovanillic Acid; Male; Mice; Mice, Inbred C57BL; Monoamine Oxidase; Neostriatum; Sex Characteristics	1994
Correlation between 1-methyl-4-phenylpyridinium ion (MPP+) levels, ascorbic acid oxidation and glutathione levels in the striatal synaptosomes of the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated rat. Neuroscience letters, 1993, Oct-29, Volume: 161, Issue:2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Ascorbic Acid; Behavior, Animal; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Dopamine Agents; Glutathione; Male; MPTP Poisoning; Nerve Endings; Oxidation-Reduction; Pyridinium Compounds; Rats; Rats, Wistar; Synaptosomes; Uric Acid	1993
GM1 ganglioside treatment partially reverses the nigrostriatal dopamine defect in the weaver mutant mouse. Brain research, 1994, Feb-14, Volume: 636, Issue:2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Dopamine; Dopamine Agents; Female; G(M1) Ganglioside; Heterozygote; Male; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Neurologic Mutants; Neostriatum; Neural Pathways; Neurons; Substantia Nigra; Tyrosine 3-Monooxygenase	1994
Studies on species sensitivity to the dopaminergic neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Part 1: Systemic administration. The Journal of pharmacology and experimental therapeutics, 1994, Volume: 270, Issue:3 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Animals; Cocaine; Dopamine; Guanethidine; Male; Mice; Microdialysis; Monoamine Oxidase; MPTP Poisoning; Neostriatum; Neurons; Premedication; Rats; Rats, Sprague-Dawley; Species Specificity; Synaptosomes	1994
Studies on species sensitivity to the dopaminergic neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Part 2: Central administration of 1-methyl-4-phenylpyridinium. The Journal of pharmacology and experimental therapeutics, 1994, Volume: 270, Issue:3 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Animals; Cocaine; Dopamine; Dose-Response Relationship, Drug; Guanethidine; Male; Mice; Monoamine Oxidase; MPTP Poisoning; Neostriatum; Premedication; Rats; Rats, Sprague-Dawley; Species Specificity	1994
MPTP-induced parkinsonism in primates: pattern of striatal dopamine loss following acute and chronic administration. Neuroscience letters, 1994, Jul-04, Volume: 175, Issue:1-2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Drug Administration Schedule; Female; Homovanillic Acid; Macaca fascicularis; Male; MPTP Poisoning; Neurons; Parkinson Disease, Secondary; Tyrosine 3-Monooxygenase	1994
Comparison of brain dopamine depletion induced by low-dose 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in young and aged rats. Neuroscience research, 1994, Volume: 20, Issue:1 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Brain; Dopamine; Homovanillic Acid; Male; Rats; Rats, Inbred Strains; Tissue Distribution	1994
Chronic administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine to monkeys: behavioural, morphological and biochemical correlates. Neuroscience, 1993, Volume: 55, Issue:3 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Callithrix; Disease Models, Animal; Dopamine; Eye Movements; Female; Homovanillic Acid; Male; Motor Activity; MPTP Poisoning; Neostriatum; Nerve Tissue Proteins; Neurons; Parkinson Disease, Secondary; Severity of Illness Index; Single-Blind Method; Substantia Nigra; Tyrosine 3-Monooxygenase; Vocalization, Animal	1993
Sulfhydryl drugs reduce neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the mouse. Journal of neural transmission. Parkinson's disease and dementia section, 1993, Volume: 6, Issue:1 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Cysteamine; Dimercaprol; Dopamine; Dopamine Agents; Glutathione; Homovanillic Acid; Male; Mice; Mice, Inbred C57BL; MPTP Poisoning; Nerve Degeneration; Nervous System Diseases; Pyridinium Compounds; Sulfhydryl Compounds	1993
Oral administration of semisynthetic sphingolipids promotes recovery of striatal dopamine concentrations in a murine model of parkinsonism. Neurology, 1994, Volume: 44, Issue:4 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Administration, Oral; Animals; Corpus Striatum; Dopamine; G(M1) Ganglioside; Homovanillic Acid; Male; Mice; Mice, Inbred C57BL; Osmolar Concentration; Parkinson Disease, Secondary; Sphingolipids; Sphingosine	1994
Effect of 4-(4-methoxy-1,2,5-thiadiazol-3-yl)-1-methyl-1,2,3,6-tetrahydropyridine , an analog of MPTP, on mouse heart norepinephrine and brain catecholamines. Neurochemistry international, 1993, Volume: 23, Issue:5 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Catecholamines; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Frontal Lobe; Heart; Homovanillic Acid; Male; Mice; Mice, Inbred Strains; Myocardium; Norepinephrine	1993
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) effects on enkephalinergic neurons in various regions of mouse brain. Neurochemistry international, 1993, Volume: 22, Issue:2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Corpus Striatum; Dopamine; Enkephalins; Frontal Lobe; Homovanillic Acid; Kinetics; Male; Mice; Mice, Inbred C57BL; Neurons; Norepinephrine; Olfactory Pathways; Protein Precursors; RNA, Messenger	1993
In vivo electrochemical studies of dopamine overflow and clearance in the striatum of normal and MPTP-treated rhesus monkeys. Journal of neurochemistry, 1996, Volume: 66, Issue:2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Caudate Nucleus; Chromatography, High Pressure Liquid; Dopamine; Dopamine Agents; Electrochemistry; Female; Homovanillic Acid; Macaca mulatta; Neostriatum; Potassium; Putamen; Reference Values; Substantia Nigra	1996
Effects of testosterone upon MPTP-induced neurotoxicity of the nigrostriatal dopaminergic system of C57/B1 mice. Brain research, 1996, Apr-09, Volume: 715, Issue:1-2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Catecholamines; Dopamine; Dopamine Agents; Female; Male; Mice; Mice, Inbred C57BL; MPTP Poisoning; Neostriatum; Nervous System Diseases; Olfactory Bulb; Orchiectomy; Substantia Nigra; Testosterone	1996
Inhibition of neuronal nitric oxide synthase prevents MPTP-induced parkinsonism in baboons. Nature medicine, 1996, Volume: 2, Issue:9 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Disease Models, Animal; Dopamine; Enzyme Inhibitors; Homovanillic Acid; Hypokinesia; Indazoles; Male; Motor Activity; Neurologic Examination; Neurons; Nitric Oxide Synthase; Papio; Parkinson Disease, Secondary; Substantia Nigra; Videotape Recording	1996
Effects of MPTP on lever-pressing for light extinction in rats. European journal of pharmacology, 1996, Mar-28, Volume: 299, Issue:1-3 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Corpus Striatum; Dopamine; Dopamine Agents; Learning; Male; Rats; Rats, Wistar; Substantia Nigra	1996
The dopamine-depleting effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in CD-1 mice are gender-dependent. Brain research, 1996, Oct-07, Volume: 735, Issue:2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Dopamine Agents; Female; Homovanillic Acid; Male; Mice; Mice, Inbred Strains; Sex Characteristics; Time Factors	1996
Preservation of autoreceptor-mediated increases in dopamine synthesis in aged mice with experimentally-induced parkinsonism. Neuroscience letters, 1997, Jan-31, Volume: 222, Issue:2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Autoreceptors; Dihydroxyphenylalanine; Dopamine; Dopamine Antagonists; Haloperidol; Male; Mice; Mice, Inbred C57BL; Neurons; Parkinson Disease, Secondary; Tyrosine 3-Monooxygenase	1997
Inhibitory effects of talipexole and pramipexole on MPTP-induced dopamine reduction in the striatum of C57BL/6N mice. Japanese journal of pharmacology, 1997, Volume: 74, Issue:1 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Animals; Azepines; Benzothiazoles; Bromocriptine; Dopamine; Dopamine Agents; Dopamine Agonists; Homovanillic Acid; In Vitro Techniques; Injections, Intraperitoneal; Male; Mice; Mice, Inbred C57BL; Neostriatum; Pramipexole; Synaptosomes; Thiazoles	1997
Thalidomide reduces MPTP-induced decrease in striatal dopamine levels in mice. Neuroscience letters, 1997, Oct-03, Volume: 234, Issue:2-3 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Anti-Inflammatory Agents; Corpus Striatum; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Homovanillic Acid; Hypnotics and Sedatives; Immunosuppressive Agents; Male; Mice; Mice, Inbred C57BL; Parkinson Disease; Thalidomide	1997
[Effect of acupuncture and Chinese medicine treatment on brain dopamine level of MPTP-lesioned C57BL mice]. Zhen ci yan jiu = Acupuncture research, 1996, Volume: 21, Issue:4 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Acupuncture Therapy; Animals; Brain; Combined Modality Therapy; Dopamine; Drugs, Chinese Herbal; Male; Mice; Mice, Inbred C57BL; Parkinson Disease, Secondary	1996
Striatal and urinary DOPAC/DA ratio may indicate a long-lasting DA release enhancement by MPP+ and MPTP. Neurochemical research, 1998, Volume: 23, Issue:2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Female; Mice; Mice, Inbred C57BL; Pyridinium Compounds; Reserpine; Synaptosomes	1998
Chronic exposure to MPTP as a primate model of progressive parkinsonism: a pilot study with a free radical scavenger. Experimental neurology, 1998, Volume: 153, Issue:2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Biomarkers; Biopterins; Disease Models, Animal; Female; Free Radical Scavengers; Homovanillic Acid; Indans; Macaca fascicularis; Male; Methoxyhydroxyphenylglycol; Motor Activity; Parkinson Disease, Secondary; Pilot Projects; Piperazines	1998
Mice deficient in group IV cytosolic phospholipase A2 are resistant to MPTP neurotoxicity. Journal of neurochemistry, 1998, Volume: 71, Issue:6 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Animals; Cell Count; Corpus Striatum; Cytosol; Dopamine Agents; Drug Resistance; Homovanillic Acid; Mice; Mice, Knockout; Neurotoxins; Phospholipases A; Phospholipases A2; Substantia Nigra; Tyrosine 3-Monooxygenase	1998
Manganese superoxide dismutase overexpression attenuates MPTP toxicity. Neurobiology of disease, 1998, Volume: 5, Issue:4 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Brain Diseases; Cerebral Cortex; Dopamine; Dopamine Agents; Gene Expression; Humans; Mice; Mice, Transgenic; Microscopy, Immunoelectron; Mitochondria; Neurons; Superoxide Dismutase; Transgenes	1998
[Effect of acidic fibroblast growth factor on experimental parkinsonism and levels of dopamine and its metabolites in the striatum of mice of various ages]. Biulleten' eksperimental'noi biologii i meditsiny, 1999, Volume: 127, Issue:5 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Administration, Intranasal; Aging; Animals; Corpus Striatum; Dopamine; Dopamine Agents; Fibroblast Growth Factor 1; Homovanillic Acid; Male; Mice; Mice, Inbred C57BL; Muscle Rigidity; Parkinson Disease, Secondary	1999
Neuroprotective rather than neurorescue or neurorestorative effect of selegiline against MPTP-induced dopaminergic toxicity. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1999, Volume: 20, Issue:2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Corpus Striatum; Dopamine; Female; Mice; Mice, Inbred C57BL; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neuroprotective Agents; Random Allocation; Selegiline; Time Factors	1999
Lactoferrin is synthesized by mouse brain tissue and its expression is enhanced after MPTP treatment. Brain research. Molecular brain research, 1999, Oct-01, Volume: 72, Issue:2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Catalase; Corpus Striatum; Dopamine; Dopamine Agonists; Enzyme Induction; Female; Gene Expression Regulation; Glutamate-Cysteine Ligase; Homovanillic Acid; Iron; Lactoferrin; Male; Mice; Mice, Inbred C57BL; MPTP Poisoning; Nerve Tissue Proteins; Neurotoxins; Organ Specificity; Parkinson Disease, Secondary; Reverse Transcriptase Polymerase Chain Reaction; Superoxide Dismutase	1999
Salicylate protects against MPTP-induced impairments in dopaminergic neurotransmission at the striatal and nigral level in mice. Naunyn-Schmiedeberg's archives of pharmacology, 1999, Volume: 360, Issue:3 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Count; Disease Models, Animal; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Free Radical Scavengers; Homovanillic Acid; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Neostriatum; Neurons; Parkinson Disease, Secondary; Protective Agents; Salicylates; Substantia Nigra; Synaptic Transmission; Tyrosine 3-Monooxygenase	1999
Cocaine reward and MPTP toxicity: alteration by regional variant dopamine transporter overexpression. Brain research. Molecular brain research, 1999, Nov-10, Volume: 73, Issue:1-2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Carrier Proteins; Chromatography, High Pressure Liquid; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Female; Gene Expression Regulation; Genetic Variation; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Inbred Strains; Mice, Transgenic; Motor Activity; MPTP Poisoning; Nerve Tissue Proteins; Promoter Regions, Genetic; Rats; Recombinant Fusion Proteins; Reward; Serotonin; Substantia Nigra; Transgenes; Tyrosine 3-Monooxygenase	1999
Neuroprotection by (R)-deprenyl and 7-nitroindazole in the MPTP C57BL/6 mouse model of neurotoxicity. Neurobiology (Budapest, Hungary), 1999, Volume: 7, Issue:2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Animals; Cattle; Corpus Striatum; Dopamine; Indazoles; Male; Mice; Mice, Inbred C57BL; Monoamine Oxidase; Neuroprotective Agents; Neurotoxins; Selegiline	1999
Mice deficient in cellular glutathione peroxidase show increased vulnerability to malonate, 3-nitropropionic acid, and 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2000, Jan-01, Volume: 20, Issue:1 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Catechols; Convulsants; Corpus Striatum; Disease Models, Animal; Dopamine Agents; Female; Free Radicals; Glutathione; Glutathione Peroxidase; Heterozygote; Homovanillic Acid; Homozygote; Huntington Disease; Male; Malonates; Mice; Mice, Inbred Strains; Mice, Knockout; MPTP Poisoning; Nitro Compounds; Oxidative Stress; Parkinson Disease, Secondary; Propionates; Tyrosine	2000
The pivotal role of iron in NF-kappa B activation and nigrostriatal dopaminergic neurodegeneration. Prospects for neuroprotection in Parkinson's disease with iron chelators. Annals of the New York Academy of Sciences, 1999, Volume: 890 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Animals; Antiparkinson Agents; Apomorphine; Corpus Striatum; Dopamine; Dopamine Agents; Ferritins; Iron; Lipid Peroxidation; Mice; Nerve Degeneration; NF-kappa B; Oxidopamine; Parkinsonian Disorders; PC12 Cells; Rats; Tyrosine 3-Monooxygenase	1999
The effects of central aromatic amino acid DOPA decarboxylase inhibition on the motor actions of L-DOPA and dopamine agonists in MPTP-treated primates. British journal of pharmacology, 2000, Volume: 129, Issue:7 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Behavior, Animal; Callithrix; Dopamine; Dopamine Agonists; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Hydrazines; Levodopa; Male; Motor Activity; Quinolones; Quinpirole; Thiophenes; Tyrosine	2000
Selenium deficiency potentiates methamphetamine-induced nigral neuronal loss; comparison with MPTP model. Brain research, 2000, Apr-17, Volume: 862, Issue:1-2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Antioxidants; Diet; Dopamine; Dopamine Agents; Homovanillic Acid; Male; Methamphetamine; Mice; Mice, Inbred C57BL; Nerve Degeneration; Neurons; Selenium; Substantia Nigra; Tyrosine 3-Monooxygenase	2000
Neuroprotection by sodium salicylate against 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine-induced neurotoxicity. Brain research, 2000, May-12, Volume: 864, Issue:2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Catalepsy; Cyclooxygenase Inhibitors; Dopamine; Dopamine Agents; Dyskinesia, Drug-Induced; Female; Free Radical Scavengers; Gentisates; Glutathione; Homovanillic Acid; Hydroxybenzoates; Hydroxyl Radical; Male; Mice; Mice, Inbred BALB C; Monoamine Oxidase; MPTP Poisoning; Neostriatum; Neuroprotective Agents; Sodium Salicylate; Substantia Nigra	2000
Inhibition of neuronal nitric oxide synthase protects against MPTP toxicity. Neuroreport, 2000, Apr-27, Volume: 11, Issue:6 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Isoquinolines; Male; Mice; MPTP Poisoning; Neurons; Neuroprotective Agents; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Substantia Nigra; Tetrahydroisoquinolines; Thiophenes; Tyrosine 3-Monooxygenase	2000
Increased striatal dopamine turnover following acute administration of rotenone to mice. Brain research, 2000, Dec-08, Volume: 885, Issue:2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Chelating Agents; Corpus Striatum; Ditiocarb; Dopamine; Dopamine Agents; Homovanillic Acid; Lactic Acid; Male; Mice; Mice, Inbred C57BL; Rotenone; Uncoupling Agents	2000
Mice with a partial deficiency of manganese superoxide dismutase show increased vulnerability to the mitochondrial toxins malonate, 3-nitropropionic acid, and MPTP. Experimental neurology, 2001, Volume: 167, Issue:1 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Carrier Proteins; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Female; Genetic Predisposition to Disease; Gentisates; Heterozygote; Homovanillic Acid; Hydroxybenzoates; Hydroxyl Radical; Male; Malonates; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Knockout; Mitochondria; Nerve Tissue Proteins; Neurodegenerative Diseases; Neurotoxins; Nitro Compounds; Propionates; Salicylic Acid; Superoxide Dismutase	2001
Evidence for a dissociation between MPTP toxicity and tyrosinase activity based on congenic mouse strain susceptibility. Experimental neurology, 2001, Volume: 168, Issue:1 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Brain; Corpus Striatum; Crosses, Genetic; Disease Models, Animal; Dopamine; Homovanillic Acid; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Neurologic Mutants; Monophenol Monooxygenase; Motor Activity; Neostriatum; Neurons; Norepinephrine; Parkinsonian Disorders; Serotonin; Species Specificity; Tyrosine 3-Monooxygenase	2001
Protective effect of riluzole on MPTP-induced depletion of dopamine and its metabolite content in mice. Metabolic brain disease, 2000, Volume: 15, Issue:3 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Corpus Striatum; Dizocilpine Maleate; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred C57BL; Neurons; Neuroprotective Agents; Pargyline; Receptors, N-Methyl-D-Aspartate; Riluzole; Sodium Channels; Time Factors	2000
SCH 23390 enhances exogenous L-DOPA decarboxylation in nigrostriatal neurons. Journal of neural transmission (Vienna, Austria : 1996), 2000, Volume: 107, Issue:4 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Aromatic-L-Amino-Acid Decarboxylases; Benzazepines; Corpus Striatum; Decarboxylation; Dihydroxyphenylalanine; Dopamine; Dopamine Agents; Dopamine Antagonists; Levodopa; Male; Mice; Substantia Nigra	2000
Transgenic ALS mice show increased vulnerability to the mitochondrial toxins MPTP and 3-nitropropionic acid. Experimental neurology, 2001, Volume: 168, Issue:2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Amyotrophic Lateral Sclerosis; Animals; Convulsants; Corpus Striatum; Dopamine; Dopamine Agents; Female; Hazardous Substances; Homovanillic Acid; Male; Mice; Mice, Transgenic; Mitochondria; Nitro Compounds; Propionates; Superoxide Dismutase	2001
Neuroprotection by caffeine and A(2A) adenosine receptor inactivation in a model of Parkinson's disease. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, May-15, Volume: 21, Issue:10 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Caffeine; Catechols; Corpus Striatum; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Immunity, Innate; Injections, Intraperitoneal; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neuroprotective Agents; Parkinsonian Disorders; Purinergic P1 Receptor Antagonists; Purines; Pyrimidines; Receptor, Adenosine A2A; Receptors, Purinergic P1; Theobromine; Triazoles; Xanthines	2001
Sensitivity to MPTP is not increased in Parkinson's disease-associated mutant alpha-synuclein transgenic mice. Journal of neurochemistry, 2001, Volume: 77, Issue:4 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; alpha-Synuclein; Amino Acid Substitution; Animals; Corpus Striatum; Dopamine; Homovanillic Acid; Humans; Mice; Mice, Transgenic; Nerve Tissue Proteins; Neurites; Neurons; Parkinson Disease; Parkinsonian Disorders; Promoter Regions, Genetic; Substantia Nigra; Synucleins; Thy-1 Antigens; Tyrosine 3-Monooxygenase	2001
Biochemical and pathological study of endogenous 1-benzyl-1,2,3,4-tetrahydroisoquinoline-induced parkinsonism in the mouse. Brain research, 2001, Jul-13, Volume: 907, Issue:1-2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Dopamine; Drug Administration Schedule; Homovanillic Acid; Hydroxyindoleacetic Acid; Isoquinolines; Male; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Parkinson Disease; Parkinson Disease, Secondary; Serotonin; Substantia Nigra; Tetrahydroisoquinolines; Tyrosine 3-Monooxygenase	2001
Relationship between the appearance of symptoms and the level of nigrostriatal degeneration in a progressive 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned macaque model of Parkinson's disease. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, Sep-01, Volume: 21, Issue:17 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Autoradiography; Behavior, Animal; Binding, Competitive; Carrier Proteins; Caudate Nucleus; Cell Count; Corpus Striatum; Disease Models, Animal; Disease Progression; Dopamine; Dopamine Plasma Membrane Transport Proteins; Drug Administration Schedule; Female; Homovanillic Acid; Macaca fascicularis; Membrane Glycoproteins; Membrane Transport Proteins; Motor Activity; Nerve Tissue Proteins; Neurons; Parkinson Disease, Secondary; Putamen; Receptors, Dopamine D2; Substantia Nigra; Tyrosine 3-Monooxygenase	2001
Riluzole (2-amino-6-trifluoromethoxy benzothiazole) attenuates MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) neurotoxicity in mice. Neuroscience letters, 2001, Oct-12, Volume: 312, Issue:1 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Astrocytes; Dopamine; Dose-Response Relationship, Drug; Down-Regulation; Drug Interactions; Excitatory Amino Acid Antagonists; Glial Fibrillary Acidic Protein; Glutamic Acid; Homovanillic Acid; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Microtubule-Associated Proteins; Neostriatum; Neurons; Neuroprotective Agents; Parkinsonian Disorders; Riluzole; Substantia Nigra; Tyrosine 3-Monooxygenase	2001
Neuroprotective effect of riluzole in MPTP-treated mice. Brain research, 2001, Nov-09, Volume: 918, Issue:1-2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Dizocilpine Maleate; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Glutamic Acid; Homovanillic Acid; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Neostriatum; Neurons; Neuroprotective Agents; Parkinsonian Disorders; Riluzole; Substantia Nigra; Synaptic Transmission; Tyrosine 3-Monooxygenase	2001
Profound astrogenesis in the striatum of adult mice following nigrostriatal dopaminergic lesion by repeated MPTP administration. Brain research. Developmental brain research, 2001, Nov-26, Volume: 131, Issue:1-2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Age Factors; Animals; Astrocytes; Bromodeoxyuridine; Cell Differentiation; Cell Division; Cell Survival; Dopamine; Dopamine Agents; Male; Mice; Mice, Inbred C57BL; MPTP Poisoning; Neostriatum; Stem Cells; Substantia Nigra; Tyrosine 3-Monooxygenase	2001
Chronic administration of pharmacological levels of melatonin does not ameliorate the MPTP-induced degeneration of the nigrostriatal pathway. Brain research, 2001, Dec-07, Volume: 921, Issue:1-2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Catecholamines; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Free Radical Scavengers; Male; Melatonin; Mice; Mice, Inbred C57BL; Neostriatum; Neural Pathways; Neurons; Neuroprotective Agents; Parkinsonian Disorders; Substantia Nigra; Tyrosine 3-Monooxygenase	2001
Deprenyl protects from MPTP-induced Parkinson-like syndrome and glutathione oxidation in rat striatum. Toxicology, 2002, Jan-25, Volume: 170, Issue:3 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Antiparkinson Agents; Behavior, Animal; Catecholamines; Dopamine; Dopamine Agents; Glutathione; Male; Neostriatum; Oxidation-Reduction; Parkinson Disease, Secondary; Rats; Rats, Wistar; Selegiline; Stereotaxic Techniques	2002
Protective action of the peroxisome proliferator-activated receptor-gamma agonist pioglitazone in a mouse model of Parkinson's disease. Journal of neurochemistry, 2002, Volume: 82, Issue:3 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Administration, Oral; Animals; Cell Count; Cell Survival; Corpus Striatum; Disease Models, Animal; Dopamine; Homovanillic Acid; Hypoglycemic Agents; Immunohistochemistry; Macrophage-1 Antigen; Male; Mice; Mice, Inbred C57BL; Neuroglia; Neurons; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Parkinsonian Disorders; Pioglitazone; Receptors, Cytoplasmic and Nuclear; Substantia Nigra; Thiazoles; Thiazolidinediones; Transcription Factors; Tyrosine 3-Monooxygenase	2002
Therapeutic effect of neuronal nitric oxide synthase inhibitor (7-nitroindazole) against MPTP neurotoxicity in mice. Metabolic brain disease, 2002, Volume: 17, Issue:3 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Arginine; Brain Chemistry; Dopamine; Dopamine Agents; Enzyme Inhibitors; Glial Fibrillary Acidic Protein; Immunohistochemistry; Indazoles; Male; Mice; Mice, Inbred C57BL; Monoamine Oxidase Inhibitors; Neostriatum; Neurotoxicity Syndromes; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Pargyline; Tyrosine 3-Monooxygenase	2002
Prevention of nitric oxide-mediated 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease in mice by tea phenolic epigallocatechin 3-gallate. Neurotoxicology, 2002, Volume: 23, Issue:3 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Blotting, Western; Catechin; Dopamine Agents; Homovanillic Acid; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Parkinson Disease, Secondary; RNA, Messenger; Substantia Nigra; Tea; Tyrosine 3-Monooxygenase	2002
Role of nitric oxide synthase against MPTP neurotoxicity in mice. Neurological research, 2002, Volume: 24, Issue:7 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Astrocytes; Calcium Channel Blockers; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glial Fibrillary Acidic Protein; Immunohistochemistry; Immunosuppressive Agents; Male; Mice; Mice, Inbred C57BL; Microtubule-Associated Proteins; Monoamine Oxidase Inhibitors; Neostriatum; Neurons; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Synthase; Parkinsonian Disorders; Substantia Nigra; Tyrosine 3-Monooxygenase	2002
Dehydroepiandrosterone (DHEA) such as 17beta-estradiol prevents MPTP-induced dopamine depletion in mice. Synapse (New York, N.Y.), 2003, Volume: 47, Issue:1 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Dehydroepiandrosterone; Dopamine; Dopamine Agents; Dopamine Plasma Membrane Transport Proteins; Estradiol; Homovanillic Acid; In Situ Hybridization; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Neuroprotective Agents; Substantia Nigra; Tyrosine 3-Monooxygenase	2003
Screening of novel pentacyclo-undecylamines for neuroprotective activity. European journal of pharmacology, 2003, Jan-01, Volume: 458, Issue:1-2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Amines; Animals; Corpus Striatum; Dizocilpine Maleate; Dopamine; Dopamine Agents; Drug Evaluation, Preclinical; Homovanillic Acid; Male; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Polycyclic Compounds	2003
Genetic or pharmacological iron chelation prevents MPTP-induced neurotoxicity in vivo: a novel therapy for Parkinson's disease. Neuron, 2003, Mar-27, Volume: 37, Issue:6 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Blotting, Western; Cell Death; Clioquinol; Dopamine; Ferritins; Gene Expression; Genetic Therapy; Homovanillic Acid; Humans; Immunohistochemistry; Iron; Iron Chelating Agents; Mice; Mice, Transgenic; Oxidative Stress; Parkinson Disease; Parkinson Disease, Secondary; Promoter Regions, Genetic; Rats; Substantia Nigra; Tyrosine 3-Monooxygenase	2003
Dextromethorphan prevents the diethyldithiocarbamate enhancement of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity in mice. Brain research, 2003, May-30, Volume: 973, Issue:2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Chelating Agents; Dextromethorphan; Ditiocarb; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Glutamic Acid; Homovanillic Acid; Male; Mesencephalon; Mice; Mice, Inbred C57BL; MPTP Poisoning; Neurons; Septal Nuclei; Serotonin; Substantia Nigra; Tyrosine 3-Monooxygenase	2003
Alpha-1B adrenergic receptor knockout mice are protected against methamphetamine toxicity. Journal of neurochemistry, 2003, Volume: 86, Issue:2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Body Temperature; Central Nervous System Stimulants; Corpus Striatum; Cytoprotection; Dopamine; Dopamine Plasma Membrane Transport Proteins; Gliosis; Homovanillic Acid; Male; Membrane Glycoproteins; Membrane Transport Proteins; Methamphetamine; Mice; Mice, Knockout; Microdialysis; Motor Activity; MPTP Poisoning; Nerve Tissue Proteins; Prazosin; Receptors, Adrenergic, alpha-1; Tyrosine 3-Monooxygenase	2003
Cerebrospinal fluid 3,4-dihydroxyphenylacetic acid level after tolcapone administration as an indicator of nigrostriatal degeneration. Experimental neurology, 2003, Volume: 183, Issue:1 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Antiparkinson Agents; Benzophenones; Biomarkers; Catechol O-Methyltransferase; Corpus Striatum; Disease Models, Animal; Dopamine; Enzyme Activation; Female; Homovanillic Acid; Male; Neurodegenerative Diseases; Nitrophenols; Parkinsonian Disorders; Predictive Value of Tests; Putamen; Saimiri; Substantia Nigra; Tolcapone	2003
Endogenous activation of mGlu5 metabotropic glutamate receptors contributes to the development of nigro-striatal damage induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004, Jan-28, Volume: 24, Issue:4 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Homovanillic Acid; Mice; Mice, Knockout; MPTP Poisoning; Neuroprotective Agents; Pyridines; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Substantia Nigra; Survival Rate; Synaptosomes	2004
Mice lacking alpha-synuclein have an attenuated loss of striatal dopamine following prolonged chronic MPTP administration. Neurotoxicology, 2004, Volume: 25, Issue:5 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; alpha-Synuclein; Animals; Blotting, Western; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Lactic Acid; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Neostriatum; Nerve Tissue Proteins; Neuropeptides; Substantia Nigra; Synucleins; Vesicular Biogenic Amine Transport Proteins; Vesicular Monoamine Transport Proteins	2004
Effects of blocking the dopamine biosynthesis and of neurotoxic dopamine depletion with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on voluntary wheel running in mice. Behavioural brain research, 2004, Oct-05, Volume: 154, Issue:2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; alpha-Methyltyrosine; Analysis of Variance; Animals; Behavior, Animal; Chromatography, High Pressure Liquid; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Drug Interactions; Homovanillic Acid; Immunohistochemistry; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Motor Activity; Nerve Tissue Proteins; Running; Time Factors; Tyrosine 3-Monooxygenase	2004
Acoustic startle response, prepulse inhibition, and spontaneous locomotor activity in MPTP-treated mice. Behavioural brain research, 2004, Oct-05, Volume: 154, Issue:2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Acoustic Stimulation; Analysis of Variance; Animals; Behavior, Animal; Brain Chemistry; Chromatography, High Pressure Liquid; Dopamine; Dopamine Agents; Drug Administration Schedule; Homovanillic Acid; Male; Mice; Mice, Inbred C57BL; Motor Activity; Neural Inhibition; Reaction Time; Reflex, Acoustic; Time Factors	2004
Involvement of cytochrome P450 2E1 in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced mouse model of Parkinson's disease. Journal of neurochemistry, 2004, Volume: 91, Issue:2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Allyl Compounds; Animals; Blotting, Western; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP2E1 Inhibitors; Disease Models, Animal; Ditiocarb; Dopamine; Drug Synergism; Enzyme Inhibitors; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microdialysis; Neostriatum; Parkinsonian Disorders; Reverse Transcriptase Polymerase Chain Reaction; Substantia Nigra; Sulfides; Tyrosine 3-Monooxygenase	2004
Selective alterations of gene expression in mice induced by MPTP. Synapse (New York, N.Y.), 2005, Volume: 55, Issue:1 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; alpha-Synuclein; Animals; beta-Synuclein; Brain Chemistry; Corpus Striatum; Dopamine; Dopamine Agents; Dopamine Plasma Membrane Transport Proteins; Gene Expression; Gene Expression Regulation; Homovanillic Acid; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Synucleins; Tyrosine 3-Monooxygenase; Vesicular Biogenic Amine Transport Proteins	2005
Effect of angiotensin-converting enzyme inhibitor perindopril on interneurons in MPTP-treated mice. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2005, Volume: 15, Issue:1 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Angiotensin-Converting Enzyme Inhibitors; Animals; Cell Count; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Drug Interactions; Electrochemistry; Homovanillic Acid; Immunohistochemistry; Interneurons; Male; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Parvalbumins; Perindopril; Time Factors; Tyrosine 3-Monooxygenase	2005
Interleukine-1beta and interleukine-6 levels in striatum and other brain structures after MPTP treatment: influence of behavioral lateralization. Journal of neuroimmunology, 2005, Volume: 158, Issue:1-2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Behavior, Animal; Brain Chemistry; Corpus Striatum; Dopamine; Dopamine Agents; Enzyme-Linked Immunosorbent Assay; Feeding Behavior; Functional Laterality; Interleukin-1; Interleukin-6; Male; Mice; Mice, Inbred C57BL; MPTP Poisoning	2005
Differential effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in the olfactory bulb and the striatum in mice. Neuroscience research, 2005, Volume: 51, Issue:1 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Blotting, Western; Corpus Striatum; Dopamine; Dopamine Agents; Dopamine Plasma Membrane Transport Proteins; Homovanillic Acid; Immunohistochemistry; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Olfactory Bulb; Sodium-Potassium-Exchanging ATPase; Tyrosine 3-Monooxygenase	2005
Simvastatin prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced striatal dopamine depletion and protein tyrosine nitration in mice. Brain research, 2005, Mar-10, Volume: 1037, Issue:1-2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Cholesterol; Dopamine; Dopamine Agents; Homovanillic Acid; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Mice; Mice, Inbred C57BL; Microglia; Neostriatum; Nitrates; Nitric Oxide; Oxidants; Simvastatin; Superoxides; Tumor Necrosis Factor-alpha; Tyrosine	2005
Absence of inclusion body formation in the MPTP mouse model of Parkinson's disease. Brain research. Molecular brain research, 2005, Mar-24, Volume: 134, Issue:1 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; alpha-Synuclein; Animals; Chromatography, High Pressure Liquid; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Drug Administration Schedule; Homovanillic Acid; Humans; Immunohistochemistry; Inclusion Bodies; Male; Mice; Mice, Inbred C57BL; MPTP Poisoning; Nerve Tissue Proteins; Neurons; Substantia Nigra; Synucleins; Tyrosine 3-Monooxygenase; Ubiquitin	2005
In mice, production of plasma IL-1 and IL-6 in response to MPTP is related to behavioral lateralization. Brain research, 2005, May-31, Volume: 1045, Issue:1-2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Corpus Striatum; Disease Models, Animal; Dopamine; Encephalitis; Forelimb; Functional Laterality; Interleukin-1; Interleukin-6; Male; Mice; Mice, Inbred C57BL; Movement; Parkinsonian Disorders	2005
MPTP treatment in mice does not transmit and cause Parkinsonian neurotoxicity in non-treated cagemates through close contact. Neuroscience research, 2005, Volume: 52, Issue:4 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Apoptosis; Blotting, Western; Chromatography, High Pressure Liquid; Disease Models, Animal; Dopamine; Immunohistochemistry; In Situ Nick-End Labeling; Male; Mice; Mice, Inbred C57BL; Parkinsonian Disorders; Statistics, Nonparametric; Substantia Nigra; Tyrosine 3-Monooxygenase	2005
Neuroprotective effects of oral administration of triacetyluridine against MPTP neurotoxicity. Neuromolecular medicine, 2004, Volume: 6, Issue:2-3 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Acetates; Animals; Dietary Supplements; Disease Models, Animal; Dopamine; Homovanillic Acid; Mice; MPTP Poisoning; Neuroprotective Agents; Neurotoxins; Uridine	2004
Neuroprotective effect of arundic acid, an astrocyte-modulating agent, in mouse brain against MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) neurotoxicity. Neuropharmacology, 2006, Volume: 50, Issue:3 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Brain; Brain Chemistry; Caprylates; Dopamine; Dopamine Plasma Membrane Transport Proteins; Drug Interactions; Homovanillic Acid; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Models, Biological; Motor Activity; Neuroprotective Agents; Neurotoxins; Nitric Oxide; Nitric Oxide Synthase; Superoxide Dismutase; Time Factors; Tyrosine 3-Monooxygenase	2006
Minocycline attenuates microglial activation but fails to mitigate striatal dopaminergic neurotoxicity: role of tumor necrosis factor-alpha. Journal of neurochemistry, 2006, Volume: 96, Issue:3 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Blotting, Western; Cell Count; Chemokine CCL2; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Drug Interactions; Glial Fibrillary Acidic Protein; Homovanillic Acid; Interleukin-6; Male; Methamphetamine; Mice; Mice, Mutant Strains; Microglia; Minocycline; Neurons; Receptors, Tumor Necrosis Factor; Reverse Transcriptase Polymerase Chain Reaction; Time Factors; Tyrosine 3-Monooxygenase	2006
Cerebellar neurotransmission in attention-deficit/hyperactivity disorder: does dopamine neurotransmission occur in the cerebellar vermis? Journal of neuroscience methods, 2006, Feb-15, Volume: 151, Issue:1 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Attention Deficit Disorder with Hyperactivity; Brain Chemistry; Cerebellum; Chromatography, High Pressure Liquid; Disease Models, Animal; Dopamine; Female; Homovanillic Acid; Macaca mulatta; Male; Microdialysis; Norepinephrine; Rats; Rats, Inbred F344; Time Factors	2006
Rifampicin attenuates the MPTP-induced neurotoxicity in mouse brain. Brain research, 2006, Apr-12, Volume: 1082, Issue:1 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Body Weight; Brain; Brain Chemistry; Cell Count; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Free Radicals; Homovanillic Acid; Immunohistochemistry; Lipid Peroxidation; Male; Mice; Mice, Inbred C57BL; Parkinsonian Disorders; Rifampin; Tyrosine 3-Monooxygenase	2006
Granulocyte-colony stimulating factor is neuroprotective in a model of Parkinson's disease. Journal of neurochemistry, 2006, Volume: 97, Issue:3 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Blotting, Northern; Brain; Cell Count; Cells, Cultured; Chromatography, High Pressure Liquid; Disease Models, Animal; Dopamine; Embryo, Mammalian; Gene Expression; Granulocyte Colony-Stimulating Factor; Green Fluorescent Proteins; Homovanillic Acid; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurons; Neuroprotective Agents; Parkinsonian Disorders; Rats; Rats, Wistar; Receptors, Granulocyte Colony-Stimulating Factor; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transfection; Tyrosine 3-Monooxygenase	2006
The potentiating effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on paraquat-induced neurochemical and behavioral changes in mice. Pharmacology, biochemistry, and behavior, 2006, Volume: 83, Issue:3 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Dopamine; Drug Synergism; Herbicides; Homovanillic Acid; Humans; Male; Methylation; Mice; Mice, Inbred C57BL; Motor Activity; MPTP Poisoning; Neurotoxins; Paraquat	2006
Persistent penetration of MPTP through the nasal route induces Parkinson's disease in mice. The European journal of neuroscience, 2006, Volume: 24, Issue:7 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Acetylcholinesterase; Administration, Intranasal; Animals; Behavior, Animal; Blotting, Western; Brain; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Drug Administration Routes; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Motor Activity; Nerve Tissue Proteins; Neurotoxins; Parkinson Disease; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Synucleins; Time Factors; Tyrosine 3-Monooxygenase	2006
Protocol for the MPTP mouse model of Parkinson's disease. Nature protocols, 2007, Volume: 2, Issue:1 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Disease Models, Animal; Dopamine; Mice; Parkinsonian Disorders; Substantia Nigra; Tyrosine 3-Monooxygenase	2007
Activated microglia affect the nigro-striatal dopamine neurons differently in neonatal and aged mice treated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Journal of neuroscience research, 2007, Volume: 85, Issue:8 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Animals, Newborn; Cell Count; Corpus Striatum; Cytokines; Dopamine; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Microglia; Nerve Degeneration; Nerve Growth Factors; Neurons; Parkinsonian Disorders; Substantia Nigra; Tyrosine 3-Monooxygenase	2007
Chronic inhalation of rotenone or paraquat does not induce Parkinson's disease symptoms in mice or rats. Experimental neurology, 2007, Volume: 208, Issue:1 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Administration, Inhalation; Administration, Intranasal; Animals; Corpus Striatum; Disease Models, Animal; Dopamine; Drug Administration Schedule; Herbicides; Insecticides; Male; Mice; Mice, Inbred C57BL; Motor Activity; Nerve Degeneration; Neurons; Paraquat; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Rotenone; Substantia Nigra	2007
Pael receptor is involved in dopamine metabolism in the nigrostriatal system. Neuroscience research, 2007, Volume: 59, Issue:4 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Drug Resistance; Genetic Predisposition to Disease; Humans; Male; Mice; Mice, Knockout; Mice, Transgenic; Neural Pathways; Neurotoxins; Oxidopamine; Parkinsonian Disorders; Receptors, G-Protein-Coupled; Substantia Nigra; Ubiquitin-Protein Ligases	2007
Neuroprotective effects of genistein on dopaminergic neurons in the mice model of Parkinson's disease. Neuroscience research, 2008, Volume: 60, Issue:2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Disease Models, Animal; Dopamine; Drug Interactions; Estradiol; Female; Gene Expression Regulation; Genistein; Homovanillic Acid; Mice; Mice, Inbred C57BL; Neurons; Neuroprotective Agents; Ovariectomy; Parkinsonian Disorders; Proto-Oncogene Proteins c-bcl-2; Substantia Nigra; Tyrosine 3-Monooxygenase	2008
Role of reactive nitrogen and reactive oxygen species against MPTP neurotoxicity in mice. Journal of neural transmission (Vienna, Austria : 1996), 2008, Volume: 115, Issue:6 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Cytoprotection; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Activators; Enzyme Inhibitors; Free Radical Scavengers; Glial Fibrillary Acidic Protein; Gliosis; Homovanillic Acid; Indazoles; Male; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Parkinsonian Disorders; Reactive Nitrogen Species; Reactive Oxygen Species; Tyrosine 3-Monooxygenase	2008
Inhibition of monoamine oxidase-B by the polyphenolic compound, curcumin and its metabolite tetrahydrocurcumin, in a model of Parkinson's disease induced by MPTP neurodegeneration in mice. Inflammopharmacology, 2008, Volume: 16, Issue:2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Curcumin; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Flavonoids; Male; Mice; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Nerve Degeneration; Neurons; Parkinson Disease; Phenols; Polyphenols	2008
Neuroprotective activities of catalpol on MPP+/MPTP-induced neurotoxicity. Neurological research, 2008, Volume: 30, Issue:6 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Brain; Cell Survival; Dopamine; Dose-Response Relationship, Drug; Glucosides; Iridoid Glucosides; Iridoids; Male; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Neurotoxicity Syndromes; Neurotoxins; PC12 Cells; Rats; Tetrazolium Salts; Thiazoles; Time Factors; Tyrosine 3-Monooxygenase	2008
Failure of acute administration with proteasome inhibitor to provide a model of Parkinson's disease in mice. Metabolic brain disease, 2008, Volume: 23, Issue:2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Cysteine Proteinase Inhibitors; Disease Models, Animal; Dopamine; Drug Administration Schedule; Homovanillic Acid; Male; Mice; Mice, Inbred C57BL; Nerve Degeneration; Neurons; Neurotoxins; Oligopeptides; Parkinsonian Disorders; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Reproducibility of Results; Time Factors; Tyrosine 3-Monooxygenase	2008
Significant effect of dimethylsulfoniopropionate on Parkinson's disease of senescence-accelerated mice induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Journal of nutritional science and vitaminology, 2008, Volume: 54, Issue:4 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Aging; Alzheimer Disease; Animals; Brain; Disease Models, Animal; Dopamine; Immobilization; Male; Mice; MPTP Poisoning; Neurotoxins; Norepinephrine; Sulfonium Compounds; Tremor	2008
Potential mechanisms of neuroprotection induced by low dose total-body gamma-irradiation in C57 mice administered with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Neuroscience letters, 2009, Jan-30, Volume: 450, Issue:2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Chromatography, High Pressure Liquid; Dopamine; Dose-Response Relationship, Radiation; Homovanillic Acid; Male; Mice; Mice, Inbred C57BL; Neurotoxicity Syndromes; Neurotoxins; Tyrosine 3-Monooxygenase; Whole-Body Irradiation	2009
Zonisamide increases dopamine turnover in the striatum of mice and common marmosets treated with MPTP. Journal of pharmacological sciences, 2009, Volume: 110, Issue:1 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Anticonvulsants; Biogenic Amines; Brain Chemistry; Callithrix; Dopamine; Dopamine Agents; Dyskinesia, Drug-Induced; Homovanillic Acid; Isoxazoles; Male; Mice; Mice, Inbred C57BL; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neostriatum; Neurons; Selegiline; Zonisamide	2009
Distinct effects of intranigral L-DOPA infusion in the MPTP rat model of Parkinson's disease. Journal of neural transmission. Supplementum, 2009, Issue:73 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Antiparkinson Agents; Cell Count; Disease Models, Animal; Dopamine; Drug Interactions; Gene Expression Regulation; Homovanillic Acid; Levodopa; Male; Movement; Neurons; Neurotoxins; Parkinsonian Disorders; Rats; Rats, Wistar; Reaction Time; Substantia Nigra; Tyrosine 3-Monooxygenase	2009
Biochemical alterations of the striatum in an MPTP-treated mouse model of Parkinson's disease. Metabolic brain disease, 2010, Volume: 25, Issue:2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Biomarkers; Corpus Striatum; Disease Models, Animal; Dopamine; Drug Administration Schedule; Glial Fibrillary Acidic Protein; Gliosis; Homovanillic Acid; Male; Mice; Mice, Inbred C57BL; Neurotoxins; Parkinsonian Disorders; Tyrosine 3-Monooxygenase	2010
Salicylic acid protects against chronic L-DOPA-induced 6-OHDA generation in experimental model of parkinsonism. Brain research, 2010, Jul-16, Volume: 1344 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Agents; Homovanillic Acid; Levodopa; Male; Medial Forebrain Bundle; Mice; Mice, Inbred BALB C; Neuroprotective Agents; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Salicylates	2010
Modeling a sensitization stage and a precipitation stage for Parkinson's disease using prenatal and postnatal 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine administration. Neuroscience, 2010, Sep-01, Volume: 169, Issue:3 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Birth Weight; Corpus Striatum; Disease Models, Animal; Dopamine; Female; Homovanillic Acid; Mice; Mice, Inbred C57BL; Motor Activity; Parkinson Disease; Pregnancy; Prenatal Exposure Delayed Effects; Tyrosine 3-Monooxygenase	2010
Isotopic reinforcement of essential polyunsaturated fatty acids diminishes nigrostriatal degeneration in a mouse model of Parkinson's disease. Toxicology letters, 2011, Nov-30, Volume: 207, Issue:2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; alpha-Linolenic Acid; Animals; Cell Death; Corpus Striatum; Deuterium; Disease Models, Animal; Fatty Acids, Unsaturated; Linoleic Acid; Mice; Mice, Inbred C57BL; Nerve Degeneration; Oleic Acid; Oxidative Stress; Parkinson Disease; Parkinsonian Disorders; Substantia Nigra	2011
The role of the MYD88-dependent pathway in MPTP-induced brain dopaminergic degeneration. Journal of neuroinflammation, 2011, Oct-11, Volume: 8 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Astrocytes; Autoradiography; Corpus Striatum; Dopamine; Dopaminergic Neurons; Glial Fibrillary Acidic Protein; Humans; Mice; Mice, Inbred C57BL; Mice, Knockout; MPTP Poisoning; Myeloid Differentiation Factor 88; Neurotoxins; Signal Transduction; Substantia Nigra; Toll-Like Receptors	2011
Pegylated granulocyte colony-stimulating factor conveys long-term neuroprotection and improves functional outcome in a model of Parkinson's disease. Brain : a journal of neurology, 2012, Volume: 135, Issue:Pt 6 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Chromatography, High Pressure Liquid; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Filgrastim; Granulocyte Colony-Stimulating Factor; Homovanillic Acid; Injections, Subcutaneous; Male; Mice; Mice, Inbred C57BL; Motor Activity; Neurons; Neuroprotective Agents; Parkinson Disease; Polyethylene Glycols; Rats; Rats, Wistar; Recombinant Proteins; Rotarod Performance Test; Time Factors; Tyrosine 3-Monooxygenase	2012
Aging of the dopaminergic system and motor behavior in mice intoxicated with the parkinsonian toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Journal of neurochemistry, 2012, Volume: 122, Issue:5 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Age Factors; Aging; Animals; Behavior, Animal; Brain; Disease Models, Animal; Dopamine; Gene Expression Regulation; Homovanillic Acid; Male; Mice; Mice, Inbred C57BL; Motor Activity; MPTP Poisoning; Neurotoxins; Rotarod Performance Test; Statistics as Topic; Tyrosine 3-Monooxygenase	2012
Simultaneous measurement of serotonin, dopamine and their metabolites in mouse brain extracts by high-performance liquid chromatography with mass spectrometry following derivatization with ethyl chloroformate. Biological & pharmaceutical bulletin, 2013, Volume: 36, Issue:2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Chromatography, High Pressure Liquid; Dopamine; Formic Acid Esters; Homovanillic Acid; Male; Mass Spectrometry; Mice; Mice, Inbred C57BL; Neurotoxins; Serotonin	2013
Pharmacokinetic, neurochemical, stereological and neuropathological studies on the potential effects of paraquat in the substantia nigra pars compacta and striatum of male C57BL/6J mice. Neurotoxicology, 2013, Volume: 37 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Astrocytes; Basal Ganglia; Cell Death; Dopamine; Dopaminergic Neurons; Dose-Response Relationship, Drug; Drug Administration Schedule; Half-Life; Herbicides; Homovanillic Acid; Injections, Intraperitoneal; Male; Metabolic Clearance Rate; Mice; Mice, Inbred C57BL; Microglia; MPTP Poisoning; Nerve Degeneration; Paraquat; Substantia Nigra; Tyrosine 3-Monooxygenase	2013
Perturbation of transcription factor Nur77 expression mediated by myocyte enhancer factor 2D (MEF2D) regulates dopaminergic neuron loss in response to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). The Journal of biological chemistry, 2013, May-17, Volume: 288, Issue:20 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Calpain; Cell Death; Cyclin-Dependent Kinase 5; Dopaminergic Neurons; Gene Expression Regulation; Male; MEF2 Transcription Factors; Mice; Mice, Knockout; Myogenic Regulatory Factors; Neurotoxins; Nuclear Receptor Subfamily 4, Group A, Member 1; RNA, Small Interfering; Substantia Nigra	2013
Biochemical evaluation of the neurotoxicity of MPTP and MPP⁺ in embryonic and newborn mice. The Journal of toxicological sciences, 2013, Volume: 38, Issue:3 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Animals; Animals, Newborn; Brain; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopaminergic Neurons; Female; Homovanillic Acid; Injections, Intraperitoneal; Male; Maternal-Fetal Exchange; Mice; Mice, Inbred C57BL; Monoamine Oxidase; MPTP Poisoning; Pregnancy; Tyrosine 3-Monooxygenase	2013
Geraniol attenuates α-synuclein expression and neuromuscular impairment through increase dopamine content in MPTP intoxicated mice by dose dependent manner. Biochemical and biophysical research communications, 2013, Nov-01, Volume: 440, Issue:4 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Acyclic Monoterpenes; alpha-Synuclein; Animals; Corpus Striatum; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Lewy Bodies; Male; Mice; Mice, Inbred C57BL; Monoamine Oxidase; MPTP Poisoning; Neuromuscular Diseases; Parkinson Disease, Secondary; Substantia Nigra; Terpenes	2013
[Therapeutic effect of a natural squamosamide derivative FLZ on Parkinson's disease model mice induced by LPS plus MPTP]. Yao xue xue bao = Acta pharmaceutica Sinica, 2013, Volume: 48, Issue:10 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Acrylamides; Animals; Caffeic Acids; Corpus Striatum; Dopamine; Homovanillic Acid; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Motor Activity; Neurons; Parkinson Disease, Secondary; Random Allocation; Tyrosine 3-Monooxygenase	2013
Substantial telomere shortening in the substantia nigra of telomerase-deficient mice does not increase susceptibility to MPTP-induced dopamine depletion. Neuroreport, 2014, Mar-26, Volume: 25, Issue:5 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Dopamine Agents; Homovanillic Acid; Male; Metallothionein 3; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Neurons; Parkinsonian Disorders; Substantia Nigra; Telomerase; Telomere Shortening; Tyrosine 3-Monooxygenase	2014
Assessment of the role of multidrug resistance-associated proteins in MPTP neurotoxicity in mice. Ideggyogyaszati szemle, 2013, Nov-30, Volume: 66, Issue:11-12 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Allopurinol; Animals; Brain; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Dopamine Agents; Drug Administration Schedule; Flavanones; Homovanillic Acid; Infusions, Parenteral; Male; Mice; Mice, Inbred C57BL; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neurotoxins; Oxidative Stress; Parkinson Disease; Silymarin; Sulfinpyrazone; Uric Acid	2013
Protective effect of chinonin in MPTP-induced C57BL/6 mouse model of Parkinson's disease. Biological & pharmaceutical bulletin, 2014, Volume: 37, Issue:8 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Disease Models, Animal; Dopamine; Gait; Glutathione; Homovanillic Acid; Male; Malondialdehyde; Mice, Inbred C57BL; Neurons; Neuroprotective Agents; Neurotoxins; Parkinson Disease; Substantia Nigra; Superoxide Dismutase; Xanthones	2014
Time course of degeneration of dopaminergic neurons and respective compensatory processes in the nigrostriatal system in mice. Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections, 2014, Volume: 456, Issue:1 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopaminergic Neurons; Mice; Mice, Inbred C57BL; Substantia Nigra; Time Factors; Tyrosine 3-Monooxygenase	2014
Effect of a chronic treatment with an mGlu5 receptor antagonist on brain serotonin markers in parkinsonian monkeys. Progress in neuro-psychopharmacology & biological psychiatry, 2015, Jan-02, Volume: 56 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Benserazide; Brain; Disease Models, Animal; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Drug Combinations; Dyskinesia, Drug-Induced; Excitatory Amino Acid Antagonists; Female; Homovanillic Acid; Levodopa; Macaca fascicularis; Ovariectomy; Parkinsonian Disorders; Protein Binding; Pyridines; Serotonin	2015
(1)H NMR-based metabolomics study on a goldfish model of Parkinson's disease induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Chemico-biological interactions, 2014, Nov-05, Volume: 223 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Brain; Disease Models, Animal; Dopamine; Goldfish; Humans; Lipid Metabolism; Magnetic Resonance Spectroscopy; Metabolomics; MPTP Poisoning; Parkinson Disease; Swimming	2014
MPTP-induced parkinsonism in mice alters striatal and nigral xCT expression but is unaffected by the genetic loss of xCT. Neuroscience letters, 2015, Apr-23, Volume: 593 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Amino Acid Transport System y+; Animals; Corpus Striatum; Dopamine; Forelimb; Male; Mice, Knockout; Neurons; Parkinsonian Disorders; Substantia Nigra; Tyrosine 3-Monooxygenase	2015
Neuroprotective effects of 3-O-demethylswertipunicoside against MPTP-induced Parkinson's disease in vivo and its antioxidant properties in vitro. Brain research, 2015, Oct-22, Volume: 1624 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Biphenyl Compounds; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Glucosides; Hippocampus; Hydroxyl Radical; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Motor Activity; MPTP Poisoning; Neuroprotective Agents; Picrates; Spine; Superoxides; Tyrosine 3-Monooxygenase; Xanthones	2015
Exercise Improves Cognitive Impairment and Dopamine Metabolism in MPTP-Treated Mice. Neurotoxicity research, 2016, Volume: 29, Issue:1 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Catalepsy; Cognition Disorders; Conditioning, Psychological; Dopamine; Exercise Test; Exploratory Behavior; Fear; Homovanillic Acid; Locomotion; Male; Maze Learning; Mice; Mice, Inbred C57BL; Neurotoxins; Tyrosine 3-Monooxygenase	2016
Evidence for a role of adaptive immune response in the disease pathogenesis of the MPTP mouse model of Parkinson's disease. Glia, 2016, Volume: 64, Issue:3 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Adaptive Immunity; Analysis of Variance; Animals; Calcium-Binding Proteins; Disease Models, Animal; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Histocompatibility Antigens Class II; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microfilament Proteins; MPTP Poisoning; RNA, Messenger; Time Factors; Tyrosine 3-Monooxygenase	2016
Ursolic acid attenuates oxidative stress in nigrostriatal tissue and improves neurobehavioral activity in MPTP-induced Parkinsonian mouse model. Journal of chemical neuroanatomy, 2016, Volume: 71 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Corpus Striatum; Dopamine; Dopaminergic Neurons; Dose-Response Relationship, Drug; Homovanillic Acid; Male; Mice; Neuroprotective Agents; Oxidative Stress; Parkinson Disease; Pars Compacta; Substantia Nigra; Triterpenes; Tyrosine 3-Monooxygenase; Ursolic Acid	2016
Physical exercise counteracts MPTP-induced changes in neural precursor cell proliferation in the hippocampus and restores spatial learning but not memory performance in the water maze. Behavioural brain research, 2016, 07-01, Volume: 307 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Bromodeoxyuridine; Cell Proliferation; Disease Models, Animal; Dopamine; Doublecortin Domain Proteins; Female; Hippocampus; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microtubule-Associated Proteins; MPTP Poisoning; Nestin; Neural Stem Cells; Neuropeptides; Physical Conditioning, Animal; Reaction Time; Spatial Learning	2016
MPTP neurotoxicity is highly concordant between the sexes among BXD recombinant inbred mouse strains. Neurotoxicology, 2016, Volume: 55 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Disease Models, Animal; Dopamine; Female; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Homovanillic Acid; Male; Mice; Mice, Inbred Strains; MPTP Poisoning; Serotonin; Sex Characteristics; Species Specificity; Tyrosine 3-Monooxygenase	2016
Effect of MPTP on mRNA expression of PGC-1α in mouse brain. Brain research, 2017, 04-01, Volume: 1660 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Dopamine; Dopamine Agents; Gene Expression; Homovanillic Acid; Male; Mice, Inbred C57BL; MPTP Poisoning; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Protein Isoforms; Random Allocation; RNA, Messenger; Time Factors	2017
GPR55: A therapeutic target for Parkinson's disease? Neuropharmacology, 2017, Volume: 125 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Antiparkinson Agents; Basal Ganglia; Calcium-Binding Proteins; Cannabidiol; Cannabinoid Receptor Agonists; Catalepsy; Corpus Striatum; Dopamine; Haloperidol; Homovanillic Acid; Male; Mice, Inbred C57BL; Microfilament Proteins; Neurons; Parkinsonian Disorders; Receptors, Cannabinoid; RNA, Messenger	2017
TREM2 overexpression attenuates neuroinflammation and protects dopaminergic neurons in experimental models of Parkinson's disease. Experimental neurology, 2018, Volume: 302 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Adenoviridae; Animals; Cyclooxygenase 2; Cytokines; Disease Models, Animal; Dopaminergic Neurons; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Inflammation; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; NF-kappa B; Parkinsonian Disorders; Receptors, Immunologic; Signal Transduction; Toll-Like Receptor 4; Tyrosine 3-Monooxygenase	2018
Peripheral Administration of Tetanus Toxin Hc Fragment Prevents MPP Neurotoxicity research, 2018, Volume: 34, Issue:1 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Administration Schedule; Functional Laterality; Homovanillic Acid; Male; Movement; MPTP Poisoning; Neuroprotective Agents; Peptide Fragments; Rats; Rats, Sprague-Dawley; Substantia Nigra; Synaptosomes; Tetanus Toxin; Time Factors; Tritium; Tyrosine 3-Monooxygenase	2018
Octanoic acid prevents reduction of striatal dopamine in the MPTP mouse model of Parkinson's disease. Pharmacological reports : PR, 2018, Volume: 70, Issue:5 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Caprylates; Corpus Striatum; Dopamine; Homovanillic Acid; Male; Mice; Neuroprotective Agents; Parkinson Disease; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Phosphoenolpyruvate Carboxykinase (GTP)	2018