Page last updated: 2024-09-03

3,4-dihydroxyphenylacetaldehyde and rotenone

3,4-dihydroxyphenylacetaldehyde has been researched along with rotenone in 3 studies

Compound Research Comparison

Studies
(3,4-dihydroxyphenylacetaldehyde)
Trials
(3,4-dihydroxyphenylacetaldehyde)
Recent Studies (post-2010)
(3,4-dihydroxyphenylacetaldehyde)
Studies
(rotenone)
Trials
(rotenone)
Recent Studies (post-2010) (rotenone)
990504,40761,648

Protein Interaction Comparison

ProteinTaxonomy3,4-dihydroxyphenylacetaldehyde (IC50)rotenone (IC50)
Bile salt export pumpHomo sapiens (human)8
NADH-ubiquinone oxidoreductase chain 1Bos taurus (cattle)0.015
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrialBos taurus (cattle)0.0051
Cytochrome P450 2C19Homo sapiens (human)3.6486
5-hydroxytryptamine receptor 6Homo sapiens (human)0.87
Acyl carrier protein, mitochondrialBos taurus (cattle)0.0051

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Eisenhofer, G; Harvey-White, J; Hayakawa, Y; Kirk, K; Kopin, IJ; Lamensdorf, I1
Eisenhofer, G; Harvey-White, J; Kirk, K; Kopin, IJ; Lamensdorf, I; Nechustan, A1
Brown, AM; Burke, WJ; Conway, AD; Jain, JC; Kristal, BS; Li, SW; Ulluci, PA1

Other Studies

3 other study(ies) available for 3,4-dihydroxyphenylacetaldehyde and rotenone

ArticleYear
Metabolic stress in PC12 cells induces the formation of the endogenous dopaminergic neurotoxin, 3,4-dihydroxyphenylacetaldehyde.
    Journal of neuroscience research, 2000, May-15, Volume: 60, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cell Differentiation; Cell Line; Cell Survival; Dopamine; Dose-Response Relationship, Drug; Electron Transport; Glucose; Homovanillic Acid; Humans; L-Lactate Dehydrogenase; Mitochondria; Nerve Growth Factor; Neurons; Neurotoxins; Oxidation-Reduction; PC12 Cells; Phenylethyl Alcohol; Rats; Rotenone; Stress, Physiological; Uncoupling Agents

2000
3,4-Dihydroxyphenylacetaldehyde potentiates the toxic effects of metabolic stress in PC12 cells.
    Brain research, 2000, Jun-23, Volume: 868, Issue:2

    Topics: 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Animals; Antioxidants; Dopamine; Energy Metabolism; Enzyme Inhibitors; Estrogens, Non-Steroidal; Fluorenes; Hydantoins; Isoflavones; Mitochondria; Neurons; Oxidation-Reduction; Oxidative Stress; Parkinson Disease; PC12 Cells; Phenylethyl Alcohol; Rats; Rotenone

2000
Selective dopaminergic vulnerability: 3,4-dihydroxyphenylacetaldehyde targets mitochondria.
    Free radical biology & medicine, 2001, Apr-15, Volume: 30, Issue:8

    Topics: 3,4-Dihydroxyphenylacetic Acid; 4-Aminobenzoic Acid; Aminobenzoates; Animals; Aristolochic Acids; Cell Death; Cell Differentiation; Cyclosporine; Dopamine; Dopamine Antagonists; Enzyme Inhibitors; Ion Channels; Male; Membrane Proteins; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Nerve Growth Factor; para-Aminobenzoates; Parkinson Disease; PC12 Cells; Phenanthrenes; Rats; Rats, Inbred F344; Respiration; Rotenone; Trifluoperazine; Uncoupling Agents

2001