Page last updated: 2024-09-03

3,4-dihydroxyphenylacetaldehyde and disulfiram

3,4-dihydroxyphenylacetaldehyde has been researched along with disulfiram in 5 studies

Compound Research Comparison

Studies
(3,4-dihydroxyphenylacetaldehyde)
Trials
(3,4-dihydroxyphenylacetaldehyde)
Recent Studies (post-2010)
(3,4-dihydroxyphenylacetaldehyde)
Studies
(disulfiram)
Trials
(disulfiram)
Recent Studies (post-2010) (disulfiram)
990503,776175723

Protein Interaction Comparison

ProteinTaxonomy3,4-dihydroxyphenylacetaldehyde (IC50)disulfiram (IC50)
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonasePlasmodium berghei10.1
Spike glycoproteinBetacoronavirus England 19.35
Replicase polyprotein 1abBetacoronavirus England 19.35
type-1 angiotensin II receptorHomo sapiens (human)6.637
perilipin-5Homo sapiens (human)1.622
perilipin-1Homo sapiens (human)6.959
apelin receptorHomo sapiens (human)2.63
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform aHomo sapiens (human)4.2905
bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferaseMycobacterium tuberculosis H37Rv85.03
Transmembrane protease serine 2Homo sapiens (human)9.35
Bile salt export pumpHomo sapiens (human)10
Carbamate kinaseGiardia intestinalis0.6
Retinal dehydrogenase 1Homo sapiens (human)0.13
Aldehyde dehydrogenase, mitochondrialHomo sapiens (human)3.4
Cytochrome P450 1A2Homo sapiens (human)4
Procathepsin LHomo sapiens (human)9.35
Alpha-2A adrenergic receptorHomo sapiens (human)4.904
Fructose-1,6-bisphosphatase 1Homo sapiens (human)1.3756
Replicase polyprotein 1aSevere acute respiratory syndrome-related coronavirus9.35
Replicase polyprotein 1abHuman coronavirus 229E9.35
Replicase polyprotein 1abSevere acute respiratory syndrome-related coronavirus9.35
Adenosine receptor A3Homo sapiens (human)0.356
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 26.9171
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)0.356
Alpha-2B adrenergic receptorHomo sapiens (human)3.218
D(1A) dopamine receptorHomo sapiens (human)2.158
D(4) dopamine receptorHomo sapiens (human)3.15
C-X-C chemokine receptor type 2Homo sapiens (human)6.013
Mitogen-activated protein kinase 3 Homo sapiens (human)1.51
Protein-lysine 6-oxidaseHomo sapiens (human)0.32
Lysine-specific demethylase 5AHomo sapiens (human)10
Caspase-1Homo sapiens (human)1.8
Mu-type opioid receptorHomo sapiens (human)3.511
D(3) dopamine receptorHomo sapiens (human)1.084
Kappa-type opioid receptorHomo sapiens (human)6.103
C-C chemokine receptor type 2Homo sapiens (human)2.468
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)0.356
C-C chemokine receptor type 4Homo sapiens (human)8.395
Gasdermin-DHomo sapiens (human)0.4
Lysyl oxidase homolog 3Homo sapiens (human)0.093
Spike glycoproteinSevere acute respiratory syndrome-related coronavirus9.35
Sodium-dependent dopamine transporter Homo sapiens (human)4.637
NACHT, LRR and PYD domains-containing protein 3 Mus musculus (house mouse)3
Lysyl oxidase homolog 4Homo sapiens (human)0.059
Histone-lysine N-methyltransferase EHMT2Homo sapiens (human)0.6
Monoglyceride lipaseHomo sapiens (human)0.8095
Angiotensin-converting enzyme 2 Homo sapiens (human)9.35
Gasdermin-DMus musculus (house mouse)0.4
Histone-lysine N-methyltransferase EHMT1Homo sapiens (human)1.6
Lysyl oxidase homolog 2Homo sapiens (human)0.15
large T antigenBetapolyomavirus macacae10.73

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19903 (60.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Helander, A; Tottmar, O2
Nilsson, GE1
Bonnet, JJ; Costentin, J; Dourmap, N; Janin, F; Legros, H1
Bonnet, JJ; Costentin, J; Dingeval, MG; Janin, F; Legros, H1

Other Studies

5 other study(ies) available for 3,4-dihydroxyphenylacetaldehyde and disulfiram

ArticleYear
Effects of ethanol, acetaldehyde and disulfiram on the metabolism of biogenic aldehydes in isolated human blood cells and platelets.
    Biochemical pharmacology, 1987, Nov-15, Volume: 36, Issue:22

    Topics: 3,4-Dihydroxyphenylacetic Acid; Acetaldehyde; Blood Platelets; Cells, Cultured; Disulfiram; Dopamine; Erythrocytes; Ethanol; Humans; Hydroxyindoleacetic Acid; Leukocytes; Phenylacetates; Phenylethyl Alcohol; Serotonin

1987
Metabolism of biogenic aldehydes in human blood: effects of ethanol, acetaldehyde and disulfiram.
    Alcohol and alcoholism (Oxford, Oxfordshire). Supplement, 1987, Volume: 1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Acetaldehyde; Aldehydes; Blood Platelets; Disulfiram; Erythrocytes; Ethanol; Humans; Hydroxyindoleacetic Acid; Leukocytes

1987
Aldehyde dehydrogenase activity in brain and liver of the rainbow trout (Salmo gairdneri Richardson).
    The Journal of experimental zoology, 1988, Volume: 247, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aldehyde Dehydrogenase; Animals; Brain; Cell Fractionation; Chromatography, High Pressure Liquid; Cytosol; Disulfiram; Glutamate Dehydrogenase; Hydrogen-Ion Concentration; Kinetics; L-Lactate Dehydrogenase; Liver; Magnesium; Male; Microsomes; Mitochondria; Rats; Rats, Inbred Strains; Salmonidae; Trout

1988
Semi-chronic increase in striatal level of 3,4-dihydroxyphenylacetaldehyde does not result in alteration of nigrostriatal dopaminergic neurones.
    Journal of neuroscience research, 2004, Feb-01, Volume: 75, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aldehyde Dehydrogenase; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Disulfiram; Dopamine; Dopamine Agents; Enzyme Inhibitors; Levodopa; Male; Neurons; Rats; Rats, Sprague-Dawley; Time Factors

2004
Toxicity of a treatment associating dopamine and disulfiram for catecholaminergic neuroblastoma SH-SY5Y cells: relationships with 3,4-dihydroxyphenylacetaldehyde formation.
    Neurotoxicology, 2004, Volume: 25, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Catecholamines; Cell Line, Tumor; Cell Survival; Disulfiram; Dopamine; Humans; Neuroblastoma

2004