3,4-dihydroxybenzohydroxamic acid and 3,4,5-trihydroxybenzamidoxime

3,4-dihydroxybenzohydroxamic acid has been researched along with 3,4,5-trihydroxybenzamidoxime in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (47.06)18.2507
2000's7 (41.18)29.6817
2010's2 (11.76)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Elford, HL; Novotny, L; Romanova, D; Szekeres, T; Vachalkova, A1
Macáková, K; Miadoková, E; Podstavková, S; Vlcek, D1
Birch, NJ; Elford, HL; Gallicchio, VS; Hughes, NK; Mayhew, C; Oakley, O; Phillips, J; Piper, J1
Chitambar, CR; Elford, HL; Myette, MS1
Birch, NJ; Elford, HL; Gallicchio, VS; Greenberg, RN; Mayhew, CN; Phillips, JD1
Adunyah, SE; Asakura, T; Elford, HL; Fasold, H; Horiuchi, K; Iyamu, WE; Turner, EA1
Smart, T1
Ahmed, MM; Chendil, D; Elford, HL; Gallicchio, VS; Greenberg, RN; Mampuru, LJ; Mayhew, CN; Phillips, JD1
Cibull, ML; Elford, HL; Gallicchio, VS; Mayhew, CN; Phillips, JD1
Chou, TC; Dong, HJ; Figul, M; Rainov, NG; Söling, A1
Duvall, W; Elford, HL; Gallicchio, VS; Hagan, E; Inayat, MS; Mayhew, CN; Sumpter, LR; Yost, EE1
Cibull, M; Elford, HL; Gallicchio, VS; Inayat, M; Mayhew, CN; Phillips, JD; Sumpter, R1
Belcher, J; Hebbel, RP; Kaul, DK; Kelm, RJ; Kollander, R; Liu, XD; Mahaseth, H; Solovey, A; Vercellotti, GM1
Bhave, S; Elford, H; McVoy, MA1

Other Studies

17 other study(ies) available for 3,4-dihydroxybenzohydroxamic acid and 3,4,5-trihydroxybenzamidoxime

ArticleYear
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
The new inhibitors of ribonucleotide reductase--comparison of some physico-chemical properties.
    Journal of pharmaceutical and biomedical analysis, 1997, Volume: 15, Issue:7

    Topics: Benzamidines; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Hydrogen-Ion Concentration; Hydroxamic Acids; Oximes; Polarography; Ribonucleotide Reductases; Spectrophotometry, Ultraviolet

1997
Genotoxic properties of the newly synthesized antineoplastic agents amidox, didox and trimidox.
    Die Pharmazie, 1997, Volume: 52, Issue:7

    Topics: Animals; Antineoplastic Agents; Benzamidines; Enzyme Inhibitors; Frameshift Mutation; Hydroxamic Acids; In Vitro Techniques; Mutagenicity Tests; Mutagens; Oximes; Rats; Ribonucleotide Reductases; Salmonella typhimurium; Subcellular Fractions

1997
Effective use of ribonucleotide reductase inhibitors (Didox and Trimidox) alone or in combination with didanosine (ddI) to suppress disease progression and increase survival in murine acquired immunodeficiency syndrome (MAIDS).
    Cellular and molecular biology (Noisy-le-Grand, France), 1997, Volume: 43, Issue:7

    Topics: Animals; Antiviral Agents; Benzamidines; Biomarkers; Didanosine; Disease Progression; Drug Therapy, Combination; Female; Hydroxamic Acids; Leukemia Virus, Murine; Mice; Mice, Inbred C57BL; Murine Acquired Immunodeficiency Syndrome; Ribonucleotide Reductases; Survival Rate

1997
Interaction of gallium nitrate with other inhibitors of ribonucleotide reductase: effects on the proliferation of human leukemic cells.
    Cancer letters, 1998, Jul-17, Volume: 129, Issue:2

    Topics: Antineoplastic Agents; Benzamidines; Cell Division; Deoxycytidine; Drug Synergism; Enzyme Inhibitors; Gallium; Gemcitabine; Humans; Hydroxamic Acids; Hydroxyurea; Oximes; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Ribonucleotide Reductases; Tumor Cells, Cultured

1998
Protease inhibitors and subtypes.
    AIDS patient care and STDs, 1999, Volume: 13, Issue:4

    Topics: Benzamidines; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Hydroxamic Acids; Serotyping; Treatment Outcome

1999
Drug targets cellular enzyme.
    AIDS patient care and STDs, 1999, Volume: 13, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Animals; Anti-HIV Agents; Benzamidines; Disease Models, Animal; Drug Resistance, Microbial; Humans; Hydroxamic Acids; Immunity, Cellular; Mice; Ribonucleotide Reductases; Sensitivity and Specificity

1999
In vivo and in vitro comparison of the short-term hematopoietic toxicity between hydroxyurea and trimidox or didox, novel ribonucleotide reductase inhibitors with potential anti-HIV-1 activity.
    Stem cells (Dayton, Ohio), 1999, Volume: 17, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Anemia; Animals; Anti-HIV Agents; Benzamidines; Cells, Cultured; Colony-Forming Units Assay; Enzyme Inhibitors; Female; Femur; Hematopoiesis; Hematopoietic Stem Cells; Humans; Hydroxamic Acids; Hydroxyurea; In Vitro Techniques; Lymphocytes; Macrophages; Mice; Mice, Inbred C57BL; Neutrophils; Organ Size; Ribonucleotide Reductases; Spleen

1999
Enhancement of hemoglobin and F-cell production by targeting growth inhibition and differentiation of K562 cells with ribonucleotide reductase inhibitors (didox and trimidox) in combination with streptozotocin.
    American journal of hematology, 2000, Volume: 63, Issue:4

    Topics: Antineoplastic Agents; Benzamidines; Cell Differentiation; Cell Division; Drug Therapy, Combination; Enzyme Inhibitors; Fetal Hemoglobin; Hemoglobin, Sickle; Humans; Hydroxamic Acids; K562 Cells; Ribonucleotide Reductases; Streptozocin

2000
Beyond hydroxyurea.
    GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1995, Volume: 9, Issue:9

    Topics: Animals; Antiviral Agents; Benzamidines; Dipyridamole; Disease Models, Animal; Floxuridine; Fluorouracil; Humans; Hydroxamic Acids; Hydroxyurea; Mice; Murine Acquired Immunodeficiency Syndrome; Ribonucleotide Reductases

1995
Suppression of retrovirus-induced immunodeficiency disease (murine AIDS) by trimidox and didox: novel ribonucleotide reductase inhibitors with less bone marrow toxicity than hydroxyurea.
    Antiviral research, 2002, Volume: 56, Issue:2

    Topics: Animals; Benzamidines; Bone Marrow Cells; DNA, Viral; Female; Femur; Free Radical Scavengers; Hematopoietic Stem Cells; Hydroxamic Acids; Hydroxyurea; Hypergammaglobulinemia; Leukemia Virus, Murine; Leukemia, Experimental; Mice; Mice, Inbred C57BL; Murine Acquired Immunodeficiency Syndrome; Proviruses; Retroviridae Infections; Ribonucleotide Reductases; Spleen; Splenomegaly; Tumor Virus Infections

2002
Short-term treatment with novel ribonucleotide reductase inhibitors Trimidox and Didox reverses late-stage murine retrovirus-induced lymphoproliferative disease with less bone marrow toxicity than hydroxyurea.
    Antiviral chemistry & chemotherapy, 2002, Volume: 13, Issue:5

    Topics: Animals; Antiviral Agents; Benzamidines; Blood Cell Count; Body Weight; Bone Marrow; Hydroxamic Acids; Hydroxyurea; Leukemia Virus, Murine; Lymphoproliferative Disorders; Mice; Spleen; Time Factors

2002
Combined effects of temozolomide and the ribonucleotide reductase inhibitors didox and trimidox in malignant brain tumor cells.
    Cancer chemotherapy and pharmacology, 2003, Volume: 52, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Benzamidines; Brain Neoplasms; Dacarbazine; Drug Synergism; Enzyme Inhibitors; Glioma; Humans; Hydroxamic Acids; Ribonucleotide Reductases; Temozolomide; Tumor Cells, Cultured

2003
In vivo examination of hydroxyurea and the novel ribonucleotide reductase inhibitors trimidox and didox in combination with the reverse transcriptase inhibitor abacavir: suppression of retrovirus-induced immunodeficiency disease.
    Antiviral research, 2004, Volume: 62, Issue:3

    Topics: Animals; Antiviral Agents; Benzamidines; Bone Marrow Cells; Dideoxynucleosides; Disease Models, Animal; Drug Therapy, Combination; Hematopoietic Stem Cells; Hydroxamic Acids; Hydroxyurea; Mice; Mice, Inbred C57BL; Murine Acquired Immunodeficiency Syndrome; Ribonucleotide Reductases; Spleen; Splenomegaly

2004
Combination of inhibitors of lymphocyte activation (hydroxyurea, trimidox, and didox) and reverse transcriptase (didanosine) suppresses development of murine retrovirus-induced lymphoproliferative disease.
    Antiviral research, 2005, Volume: 65, Issue:1

    Topics: Animals; Antiviral Agents; B-Lymphocytes; Benzamidines; Didanosine; Drug Therapy, Combination; Enzyme Inhibitors; Female; Hydroxamic Acids; Hydroxyurea; Leukemia Virus, Murine; Leukemia, Experimental; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Murine Acquired Immunodeficiency Syndrome; Retroviridae Infections; Reverse Transcriptase Inhibitors; Ribonucleotide Reductases; Treatment Outcome; Tumor Virus Infections

2005
Robust vascular protective effect of hydroxamic acid derivatives in a sickle mouse model of inflammation.
    Microcirculation (New York, N.Y. : 1994), 2006, Volume: 13, Issue:6

    Topics: Anemia, Sickle Cell; Animals; Benzamidines; Blood Coagulation; Cell Communication; Chronic Disease; Disease Models, Animal; Drug Evaluation, Preclinical; Endothelial Cells; Enzyme Inhibitors; Humans; Hydroxamic Acids; Inflammation; Leukocytes; Mice; Mice, Transgenic; Thromboplastin

2006
Ribonucleotide reductase inhibitors hydroxyurea, didox, and trimidox inhibit human cytomegalovirus replication in vitro and synergize with ganciclovir.
    Antiviral research, 2013, Volume: 100, Issue:1

    Topics: Antiviral Agents; Benzamidines; Cell Line; Cytomegalovirus; Cytomegalovirus Infections; Drug Synergism; Ganciclovir; Humans; Hydroxamic Acids; Hydroxyurea; Inhibitory Concentration 50; Ribonucleotide Reductases

2013