Compounds > 3,4-dihydro-5-methyl-1(2h)-isoquinolinone
Page last updated: 2024-09-04

3,4-dihydro-5-methyl-1(2h)-isoquinolinone and pj-34

3,4-dihydro-5-methyl-1(2h)-isoquinolinone has been researched along with pj-34 in 1 studies

Compound Research Comparison

Studies
(3,4-dihydro-5-methyl-1(2h)-isoquinolinone)		Trials
(3,4-dihydro-5-methyl-1(2h)-isoquinolinone)		Recent Studies (post-2010)
(3,4-dihydro-5-methyl-1(2h)-isoquinolinone)		Studies
(pj-34)		Trials
(pj-34)		Recent Studies (post-2010) (pj-34)
16021709

Protein Interaction Comparison

ProteinTaxonomy3,4-dihydro-5-methyl-1(2h)-isoquinolinone (IC50)pj-34 (IC50)
Poly [ADP-ribose] polymerase 2Mus musculus (house mouse)0.0405
Poly [ADP-ribose] polymerase tankyrase-1Homo sapiens (human)1.1077
Poly [ADP-ribose] polymerase 1Homo sapiens (human)0.1096
Protein mono-ADP-ribosyltransferase PARP15Homo sapiens (human)8.9563
Protein mono-ADP-ribosyltransferase PARP14Homo sapiens (human)4.1843
Protein mono-ADP-ribosyltransferase PARP10Homo sapiens (human)6.3123
Protein mono-ADP-ribosyltransferase PARP12Homo sapiens (human)0.2269
Poly [ADP-ribose] polymerase tankyrase-2Homo sapiens (human)1.2683
Poly [ADP-ribose] polymerase 2Homo sapiens (human)0.1687
Protein mono-ADP-ribosyltransferase PARP4Homo sapiens (human)0.7586
Protein mono-ADP-ribosyltransferase PARP3Homo sapiens (human)1.4377

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Beaton, G; Christenson, E; Demaggio, AJ; Eksterowicz, J; Goldman, P; Herendeen, D; Kesicki, EA; McElligott, DL; Moree, WJ1

Other Studies

1 other study(ies) available for 3,4-dihydro-5-methyl-1(2h)-isoquinolinone and pj-34

ArticleYear
Identification of ring-fused pyrazolo pyridin-2-ones as novel poly(ADP-ribose)polymerase-1 inhibitors.
    Bioorganic & medicinal chemistry letters, 2008, Sep-15, Volume: 18, Issue:18

    Topics: Animals; Chickens; Combinatorial Chemistry Techniques; Drug Design; Enzyme Inhibitors; Molecular Structure; Poly(ADP-ribose) Polymerase Inhibitors; Pyrazoles; Pyridones; Structure-Activity Relationship

2008