3,4-dihydro-5-methyl-1(2h)-isoquinolinone has been researched along with dacarbazine in 2 studies
| Studies (3,4-dihydro-5-methyl-1(2h)-isoquinolinone) | Trials (3,4-dihydro-5-methyl-1(2h)-isoquinolinone) | Recent Studies (post-2010) (3,4-dihydro-5-methyl-1(2h)-isoquinolinone) | Studies (dacarbazine) | Trials (dacarbazine) | Recent Studies (post-2010) (dacarbazine) |
|---|---|---|---|---|---|
| 16 | 0 | 2 | 7,556 | 1,463 | 3,429 |
| Protein | Taxonomy | 3,4-dihydro-5-methyl-1(2h)-isoquinolinone (IC50) | dacarbazine (IC50) |
|---|---|---|---|
| Matrix metalloproteinase-9 | Homo sapiens (human) | 0.556 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Boulton, S; Curtin, NJ; Durkacz, BW; Golding, BT; Griffin, RJ; Pemberton, LC; Porteous, JK | 1 |
| Chatterjee, S; Gerson, SL; Liu, L; Taverna, P; Whitacre, CM | 1 |
2 other study(ies) available for 3,4-dihydro-5-methyl-1(2h)-isoquinolinone and dacarbazine
| Article | Year |
|---|---|
Potentiation of temozolomide-induced cytotoxicity: a comparative study of the biological effects of poly(ADP-ribose) polymerase inhibitors.
Topics: Animals; Antineoplastic Agents; Cell Survival; Dacarbazine; DNA Damage; Drug Synergism; Enzyme Inhibitors; Isoquinolines; Mice; NAD; Poly(ADP-ribose) Polymerase Inhibitors; Temozolomide | 1995 |
Pharmacologic disruption of base excision repair sensitizes mismatch repair-deficient and -proficient colon cancer cells to methylating agents.
Topics: Antineoplastic Agents, Alkylating; Carmustine; Cell Cycle; Colonic Neoplasms; Dacarbazine; DNA Repair; Drug Synergism; Humans; Hydroxylamines; Isoquinolines; Poly(ADP-ribose) Polymerase Inhibitors; Temozolomide | 1999 |